CN110898137A - 一种治疗甲亢病的药丸及其制备方法和应用 - Google Patents
一种治疗甲亢病的药丸及其制备方法和应用 Download PDFInfo
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Abstract
本发明公开了一种治疗甲亢病的药丸及其制备方法和应用，涉及中药技术领域，所述的药丸包括如下重量份数的原料组分：龙胆草2‑4份、黄芩2‑4份、栀子1‑3份、泽泻3‑5份、当归1‑2份、金花0.005‑0.01份、生地黄2‑4份、黑茶8‑12份。本发明提供的药丸使用纯天然中草药，经过提取，降低了药渣对人体造成的不良作用，使用方便，用药剂量少，绿色环保，治疗甲亢病的疗效显著，总有效率100％，无副作用，无激素对身体不会造成再次伤害。
Description
技术领域
本发明涉及中药技术领域，具体涉及一种治疗甲亢病的药丸及其制备方法和应用。
背景技术
甲状腺功能亢进症,简称甲亢，病患的甲状腺分泌过多的甲状腺激素，导致糖、蛋白质和脂肪三大类物质的代谢增强,患者会出现怕热多汗、烦躁易怒、心慌、手抖等系列症状。
甲亢病的治疗方法有三种：药物治疗、手术治疗和碘131治疗。药物治疗只能控制甲状腺激素的合成，大多数患者服药时间较长一般都在一年到两年，且目前用于治疗甲亢的药物多为西药，长期服用有副作用；手术和碘131治疗只能在服药后病情得到缓解的条件下进行；而疗程长、治疗效果不明显会使患者产生不良情绪，导致病情加重。
对于甲亢的治疗效果中医更为显著，但普遍使用的是汤剂，患者需长时间大量服药，常无法坚持，服药断断续续，得不到有效治疗。
发明内容
针对现有技术中的缺陷，本发明提供一种治疗甲亢病的药丸，包括如下重量份数的原料组分：龙胆草2-4份、黄芩2-4份、栀子1-3份、泽泻3-5份、当归1-2份、金花0.005-0.01份、生地黄2-4份、黑茶8-12份。
优选地，包括如下重量份数的原料组分：龙胆草2-3份、黄芩2-3份、栀子1-2份、泽泻3-4份、当归1-1.5份、金花0.005-0.0075份、生地黄2-3份、黑茶8-10份。
进一步优选地，包括如下重量份数的原料组分：龙胆草3份、黄芩3份、栀子2份、泽泻4份、当归1.5份、金花0.0075份、生地黄3份、黑茶10份。
上述药丸的制备方法，步骤如下：S1.将原料组分洗净，晾干，制得晾干的中药；S2.将晾干的中药进行粉碎，再向其中加入提取剂，搅拌，加热提纯，离心，制得第一提取液和第一固体残渣；S3.将第一固体残渣中加入提取剂，搅拌，加热提纯，制得第二提取液和第二固体残渣；S4.将第一提取液和第二提取液进行混合，加热，减压浓缩，制得浓缩浸膏；S5.将浓缩浸膏制成丸状，烘干，制得药丸。
步骤S2中所述的加热提纯为加热至40-50℃提纯3h；步骤S3中所述的加热提纯为加热至40-60℃提纯3h。
步骤S2中所述的提取剂为甲醇；所述的提取剂与晾干的中药的重量份数比为1：2至1：10；步骤S3中所述的提取剂为甲醇；所述的提取剂与第一固体残渣的重量份数比为1：2至1：10。
步骤S4中所述的加热为加热至60℃；所述的减压浓缩为减压浓缩至浓缩浸膏与晾干的中药的重量份数比为1：20。
步骤S5中所述的烘干为置于55-75℃烘箱中烘干。
步骤S5中所述的药丸重量为0.8g。
本发明的另一个目的在于保护上述的制备方法制得的药丸作为治疗甲亢病药品的应用。
本发明各个中药成分的功效：
龙胆草：性味，味苦、性寒。归肝、胆经。作用：清热燥湿，泻肝定惊。用于湿热黄疸，小便淋痛，阴肿阴痒，湿热带下，肝胆实火之头胀头痛，目赤肿痛，耳聋耳肿，胁痛口苦，热病惊风抽搐。
黄芩：性味，味苦，性寒。归肺、胆、脾、大肠、小肠经。作用：清热燥湿，泻火解毒，止血，安胎。用于湿温、暑湿，胸闷呕恶，湿热痞满，泻痢，黄疸，肺热咳嗽，高热烦渴，血热吐衄，痈肿疮毒，胎动不安。
栀子：性味，味苦，性寒。归心、肺、三焦经。作用：泻火除烦，清热利湿，凉血解毒；外用消肿止痛。用于热病心烦，湿热黄疸，淋证涩痛，血热吐衄，目赤肿痛，火毒疮疡，外治扭挫伤痛。
泽泻：性味，味甘，性寒。归肾、膀胱经。作用：利水，渗湿，泄热。用于小便不利，水肿胀满，呕吐，泻痢，痰饮，脚气，淋病，尿血。
当归：性味，味甘，性温。归肝、心、脾经。作用：补血，活血，调经止痛，润燥滑肠。用于血虚诸证，月经不调，经闭，痛经，症瘕结聚，崩漏，虚寒腹痛，痿痹，肌肤麻木，肠燥便难，赤痢后重，痈疽疮疡，跌扑损伤。
金花：性味，味辛，性温。归肝经。作用：祛风除湿、活血止血。用于风湿痹痛、出血。
生地黄：性味，味甘，性寒。归心、肝、肾经。作用：清热凉血，养阴，生津。用于热病舌绛烦渴，阴虚内热，骨蒸劳热，内热消渴，吐血，衄血，发斑发疹。
黑茶:含有丰富的营养成分，其中最主要的是维生素和矿物质，还有蛋白质，氨基酸和糖类物质等。饮用黑茶具有解油，减脂，抗癌，抗氧化，降血压血糖，杀菌消炎，利尿解毒的功效。
本发明的另一个目的在于保护上述的制备方法制得的药丸作为治疗甲亢病药品的应用。
本发明的有益效果体现在：本发明提供的药丸使用纯天然中草药，经过提取，降低了药渣对人体造成的不良作用，使用方便，用药剂量少，绿色环保，治疗甲亢病的疗效显著，总有效率100％，无副作用，无激素对身体不会造成再次伤害。
具体实施方式
下面将对本发明技术方案的实施例进行详细的描述。以下实施例仅用于更加清楚地说明本发明的技术方案，因此只作为示例，而不能以此来限制本发明的保护范围。
需要注意的是，除非另有说明，本申请使用的技术术语或者科学术语应当为本发明所属领域技术人员所理解的通常意义。
实施例1
一种治疗甲亢病的药丸，包括如下重量份数的原料组分：龙胆草3份、黄芩3份、栀子2份、泽泻4份、当归1.5份、金花0.0075份、生地黄3份、黑茶10份。
上述药丸的制备方法，步骤如下：S1.将原料组分洗净，晾干，制得晾干的中药；S2.将晾干的中药进行粉碎，再向其中加入提取剂，搅拌加热提纯，离心，制得第一提取液和第一固体残渣；S3.将第一固体残渣中加入提取剂，搅拌加热提纯，制得第二提取液和第二固体残渣；S4.将第一提取液和第二提取液进行混合，加热，减压浓缩，制得浓缩浸膏；S5.将浓缩浸膏制成丸状，烘干，制得药丸。
步骤S2中所述的加热提纯为加热至45℃提取3h；步骤S3中所述的加热提纯为加热至50℃提取3h。
步骤S2中所述的提取剂为甲醇；所述的提取剂与晾干的中药的重量份数比为1：6；步骤S3中所述的提取剂为甲醇；所述的提取剂与第一固体残渣的重量份数比为1：6。
步骤S4中所述的加热为加热至60℃；所述的减压浓缩为减压浓缩至浓缩浸膏与晾干的中药的重量份数比为1：20。
步骤S5中所述的烘干为置于65℃烘箱中烘干。
步骤S5中所述的药丸重量为0.8g。
实施例2
一种治疗甲亢病的药丸，包括如下重量份数的原料组分：龙胆草2份、黄芩2份、栀子1份、泽泻5份、当归2份、金花0.01份、生地黄4份、黑茶12份。
上述药丸的制备方法，步骤如下：S1.将原料组分洗净，晾干，制得晾干的中药；S2.将晾干的中药进行粉碎，再向其中加入提取剂，搅拌加热提纯，离心，制得第一提取液和第一固体残渣；S3.将第一固体残渣中加入提取剂，搅拌加热提纯，制得第二提取液和第二固体残渣；S4.将第一提取液和第二提取液进行混合，加热，减压浓缩，制得浓缩浸膏；S5.将浓缩浸膏制成丸状，烘干，制得药丸。
步骤S2中所述的加热提纯为加热至45℃提取3h；步骤S3中所述的加热提纯为加热至50℃提取3h。
步骤S2中所述的提取剂为甲醇；所述的提取剂与晾干的中药的重量份数比为1：6；步骤S3中所述的提取剂为甲醇；所述的提取剂与第一固体残渣的重量份数比为1：6。
步骤S4中所述的加热为加热至60℃；所述的减压浓缩为减压浓缩至浓缩浸膏与晾干的中药的重量份数比为1：20。
步骤S5中所述的烘干为置于65℃烘箱中烘干。
步骤S5中所述的药丸重量为0.8g。
实施例3
一种治疗甲亢病的药丸，包括如下重量份数的原料组分：龙胆草4份、黄芩4份、栀子3份、泽泻3份、当归1份、金花0.005份、生地黄2份、黑茶8份。
上述药丸的制备方法，步骤如下：S1.将原料组分洗净，晾干，制得晾干的中药；S2.将晾干的中药进行粉碎，再向其中加入提取剂，搅拌加热提纯，离心，制得第一提取液和第一固体残渣；S3.将第一固体残渣中加入提取剂，搅拌加热提纯，制得第二提取液和第二固体残渣；S4.将第一提取液和第二提取液进行混合，加热，减压浓缩，制得浓缩浸膏；S5.将浓缩浸膏制成丸状，烘干，制得药丸。
步骤S2中所述的加热提纯为加热至45℃提取3h；步骤S3中所述的加热提纯为加热至50℃提取3h。
步骤S2中所述的提取剂为甲醇；所述的提取剂与晾干的中药的重量份数比为1：6；步骤S3中所述的提取剂为甲醇；所述的提取剂与第一固体残渣的重量份数比为1：6。
步骤S4中所述的加热为加热至60℃；所述的减压浓缩为减压浓缩至浓缩浸膏与晾干的中药的重量份数比为1：20。
步骤S5中所述的烘干为置于65℃烘箱中烘干。
步骤S5中所述的药丸重量为0.8g。
实施例：
本发明实施例1中制得的药丸使用效果分析：
使用方法：每日用温水送服，每日3次，每次1丸。
选取本地确诊甲亢病患者进行临床观察，结果如表1所示：
表1
案例1
熊先生，于一年前出现双侧颈前区块肿大，伴怕热、多汗、心悸、乏力、胸闷,多食易饥,并出现失眠,性情急躁,双手发抖等不适，确诊为甲亢病，服用本发明提供的药丸，3月治愈。
案例2
王女士，半年前开始眼球轻突，甲状腺中度肿大，就医确诊为甲亢病，服用本发明提供的药丸，3月治愈。
最后应说明的是：以上各实施例仅用以说明本发明的技术方案，而非对其限制；尽管参照前述各实施例对本发明进行了详细的说明，本领域的普通技术人员应当理解：其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分或者全部技术特征进行等同替换；而这些修改或者替换，并不使相应技术方案的本质脱离本发明各实施例技术方案的范围，其均应涵盖在本发明的权利要求和说明书的范围当中。
Claims (10)
1.一种治疗甲亢病的药丸，其特征在于：包括如下重量份数的原料组分：龙胆草2-4份、黄芩2-4份、栀子1-3份、泽泻3-5份、当归1-2份、金花0.005-0.01份、生地黄2-4份、黑茶8-12份。
2.根据权利要求1所述的药丸，其特征在于：包括如下重量份数的原料组分：龙胆草2-3份、黄芩2-3份、栀子1-2份、泽泻3-4份、当归1-1.5份、金花0.005-0.0075份、生地黄2-3份、黑茶8-10份。
3.根据权利要求2所述的药丸，其特征在于：包括如下重量份数的原料组分：龙胆草3份、黄芩3份、栀子2份、泽泻4份、当归1.5份、金花0.0075份、生地黄3份、黑茶10份。
4.权利要求1-3任一所述药丸的制备方法，其特征在于：所述的制备方法，步骤如下：S1.将原料组分洗净，晾干，制得晾干的中药；S2.将晾干的中药进行粉碎，再向其中加入提取剂，搅拌，加热提纯，离心，制得第一提取液和第一固体残渣；S3.将第一次固体残渣中加入提取剂，搅拌，加热提纯，制得第二提取液和第二固体残渣；S4.将第一提取液和第二提取液进行混合，加热，减压浓缩，制得浓缩浸膏；S5.将浓缩浸膏制成丸状，烘干，制得药丸。
5.根据权利要求4所述的制备方法，其特征在于：步骤S2中所述的加热提纯为加热至40-50℃提纯3h；步骤S3中所述的加热提纯为加热至40-60℃提纯3h。
6.根据权利要求4所述的制备方法，其特征在于：步骤S2中所述的提取剂为甲醇；所述的提取剂与晾干的中药的重量份数比为1：2至1：10；步骤S3中所述的提取剂为甲醇；所述的提取剂与第一固体残渣的重量份数比为1：2至1：10。
7.根据权利要求4所述的制备方法，其特征在于：步骤S4中所述的加热为加热至60℃；所述的减压浓缩为减压浓缩至浓缩浸膏与晾干的中药的重量份数比为1：20。
8.根据权利要求4所述的制备方法，其特征在于：步骤S5中所述的烘干为置于55-75℃烘箱中烘干。
9.根据权利要求4所述的制备方法，其特征在于：步骤S5中所述的药丸重量为0.8g。
10.权利要求4所述的制备方法制得的药丸作为治疗甲亢病药品的应用。
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