CN110559314A - Composition for protecting eyesight - Google Patents

Abstract

The invention relates to a composition for protecting eyesight, which can be used for protecting eyesight and assisting treatment of fundus diseases. The composition consists of chromium, selenium, docosahexaenoic acid, zinc, lutein and carotene. Its composition by mass is: chromium 25×10 ^‑3 ‑35×10 ^‑3 parts, selenium 40×10 ^‑3 ‑60×10 ^‑3 parts, docosahexaenoic acid (DHA) 250‑350 parts, zinc 20‑50 parts, 8‑20 parts of lutein, 3‑5 parts of carotene. The composition can be applied to the preparation of drugs and health products for preventing myopia, preventing and treating lens and retinopathy, improving eyesight, relieving visual fatigue or invigorating the brain, has the function of protecting visual cells to protect eyesight, and can prevent visual fatigue, Myopia and the treatment of lens and retinopathy, as well as the effect of nourishing the brain and strengthening the brain, is also a health product for pregnant women; it is of great significance to the health care of the eyes and brain and the maintenance, stability and recovery of the lens and retinal functions.

Description

A composition for protecting eyesight

technical field

The invention relates to a composition for protecting eyesight, which is used for protecting eyesight and assisting the treatment of fundus diseases. Play an important role.

Background technique

In the modern information environment, everyone cannot live without mobile phones, computers and TVs. Screen damage to the human eye causes dry eye disease to exceed 90%, visual fatigue to exceed 93%, the incidence of primary myopia to be 48%, and the incidence of junior high school myopia to be over 90%. The incidence rate of myopia is 74.36%, the incidence rate of myopia in high school is 83.28%, and the incidence rate of myopia in college is 86.36%, and the degree of myopia is also deepening. Age-related macular degeneration, which originally occurred in the sixties and seventies, is gradually advancing. However, due to the excessively refined and unscientific eating habits, some of the trace elements necessary for our human body are lacking. However, due to the damage of the screen and light pollution, the consumption and consumption of trace elements in our body and eyes have increased significantly, resulting in the occurrence of the above eye diseases. The incidence rate increased significantly.

The eyes are the windows to the soul. The visual organs of the fetus begin to form in the fourth week of pregnancy, and the optic nerve, blood vessels, lens and retina begin to develop in 4-5 months. During this period, the scientific nutrition of the mother is extremely important. The peak period of eye development is from birth to 3 years old. From the time of birth, the vision is only the front index, and the vision develops rapidly under normal light stimulation. At the age of 1, the vision develops to about 0.2, and at the age of 3, the vision develops to about 0.2. 0.6, and vision development gradually matures at the age of 4 to 6, reaching about 1.0. Therefore, in the peak period of development, targeted collocation of nutritional science is very important.

Contents of the invention

The present invention aims at the current situation of common vision problems in the information age, and combines years of clinical research and development with a high safety and scientific proportion, which is suitable for teenagers and adults, can prevent visual fatigue and dry eye, and has the function of protecting eyesight. It is a supplement that prevents and treats lens and retinopathy, and has the effect of nourishing and strengthening the brain.

A vision-protecting composition consisting essentially of chromium, selenium, docosahexaenoic acid (DHA), zinc, lutein and carotene.

The composition is composed in parts by mass: 25×10 ^-3 -35×10 ^-3 parts of chromium, 40×10 ^-3 -60×10 ^-3 parts of selenium, 250-350 parts of docosahexaenoic acid (DHA) 20-50 parts of zinc, 8-20 parts of lutein, and 3-5 parts of carotene.

The composition in parts by mass is preferably: 30×10 ^-3 parts of chromium, 50×10 ^-3 parts of selenium, 300 parts of docosahexaenoic acid (DHA), 30 parts of zinc, 10 parts of lutein, carrot Vegetable 3 servings.

The composition preferably comprises: 25-35 μg of chromium, 40-60 μg of selenium, 250-350 mg of docosahexaenoic acid (DHA), 20-50 mg of zinc, 8-20 mg of lutein and 3-5 mg of carotene.

The composition of the composition is more preferably: 30 μg of chromium, 50 μg of selenium, 300 mg of docosahexaenoic acid (DHA), 30 mg of zinc, 10 mg of lutein, and 3 mg of carotene.

The composition of the present invention mainly comprises the following six components.

a) Chromium:

Chromium is an essential trace element for the human body. Chromium is an indispensable auxiliary component of insulin. By participating in the metabolism of sugar, it promotes the synthesis of fat and protein, thereby promoting growth and development. People with diabetes have low levels of chromium in their blood and hair, and cardiovascular disease is also associated with low levels of chromium in the body. The chromium element is related to the hardness of the eyeball wall. When the chromium element is deficient, the eyeball wall becomes soft, and the top of the cornea is the thinnest part of the entire eyeball. Under the same intraocular pressure, the thinnest part is easy to protrude, causing changes in the eye axis. Myopia or increased myopia. In the event of hyperglycemia, diabetes, and arteriosclerosis, the increase in blood sugar will cause a decrease in osmotic pressure, resulting in changes in the osmotic pressure of the lens and aqueous humor of the eye, which can also cause the lens to become convex, increase the diopter, and form myopia. Therefore, chromium deficiency is closely related to myopia. Generally speaking, the chromium content in the body of children under the age of 10 is high, but the chromium in the body will suddenly decrease from 10 to 30 years old, so myopia is most likely to occur at this stage. In the total daily dose, chromium is usually 25-35 μg, preferably 30 μg in the composition of the invention.

b) Selenium:

Selenium deficiency is an important cause of vision loss in adolescents. Selenium is an important trace element to maintain healthy vision. Selenium deficiency can lead to amblyopia, and it is also one of the important factors for children aged 0-7 to suffer from respiratory and digestive tract diseases repeatedly. Because the human body has very little requirement for selenium, such as the revised standard of Chinese nutrition in 1998, it is proposed that the daily dietary supply of selenium is: 20 micrograms for 1 to 3 years old. 40 micrograms for 4 to 6 years old, 50 micrograms for those over 7 years old. Selenium supplementation is very important for the normal development of children's eyes, especially those children who love reading, surfing the Internet, reading music and practicing the piano, and generally have the problem of excessive eye use. Selenium supplementation is especially important for them. The formation of eye diseases such as myopia and amblyopia is mainly caused by the free radicals in the eye attacking the lens, causing the protein to coagulate, and the protein accumulates and precipitates in the lens, which eventually leads to the clouding of the lens and various eye diseases. Selenium is an "antioxidant nutrient", which can remove free radicals in the lens and keep the lens transparent. In addition, low blood selenium index may also cause children to be repeatedly infected with respiratory or digestive tract diseases, indicating that selenium supplementation can greatly improve children's immunity. In the total daily dose, selenium is usually 40-60 μg, preferably 50 μg in the composition of the invention.

c) Docosahexaenoic acid (DHA):

Docosahexaenoic acid (DHA) is one of the most basic components of the human brain nerve and retinal visual cell system. The content in brain tissue is about 20%, and 60% in retinal visual cells and surrounding tissues are DHA phospholipid molecules. DHA is an important component of the cerebral cortex and retina, and is closely related to the functions of nerves and vision. Sufficient DHA can promote the development of optic nerve and improve visual acuity, and its combination with lutein can synergize.

There are approximately 101.1 billion neurons in the human brain, which is the basis for the complex functions and intelligence of the brain. The development of the brain goes through complex processes such as cell proliferation, differentiation, migration, death, and synapse formation and modification. Nutrients and energy are the material basis for brain development. 0-6 years old is a critical period for human brain development. DHA is an essential micronutrient for fetal and children's brain development. DHA can promote the formation of neural networks, speed up the release of neurotransmitters and the speed of information transmission, and can significantly repair the injured brain cells. In the last three months of pregnancy, the DHA in the fetal brain will increase by 3 to 5 times, which plays an important role in the development and function of the brain of the child.

More than 60% of the information obtained by the human brain comes from vision. Therefore, the function of vision directly affects children's response ability, spatial perception and perception speed. DHA is an important component of the retina. When DHA is deficient, the visual function is impaired, which manifests as delayed development of visual acuity and prolonged fixation time for light signal stimulation, thus affecting the baby's ability to respond and observe.

Children's intelligence includes observation, memory, thinking ability, imagination and creativity. 0-6 years old is a critical period for children's intellectual development. Studies have shown that children supplemented with DHA during this period have significantly improved cognitive, language, and motor abilities compared with other children. When DHA is lacking, the division and proliferation of fetal brain cells will be hindered, and when it is seriously lacking, it will cause brain cell development retardation and low intelligence level. Pregnant women with severe insufficient intake of DHA can give birth to very low birth weight infants, manifested as mental retardation, thinking flexibility, language expression ability, comprehension ability and fine movement are lower than normal infants.

In recent years, the incidence of asthma in children and adolescents has been increasing year by year, seriously affecting the physical and mental health and academic performance of children and adolescents. Clinical studies have found that arachidonic acid (ARA) can synthesize substances that cause inflammation and allergies in the body. If a reasonable amount of DHA is taken in, it can avoid the formation of excessive ARA, reduce excessive inflammatory reactions and allergies, and enhance immunity. . In the total daily dose, DHA is usually 250-350 mg, preferably 300 mg in the composition of the present invention.

d) Zinc:

Zinc is closely related to the eye. Zinc plays an important role in the health of retinal visual cells. The content of zinc enzyme in the eye is relatively high and its activity is strong. It is a component of retinal enzyme in the retina. With the presence of this enzyme, it can promote the absorption of vitamin A. Vitamin A is usually stored in the liver. When the human body needs it, vitamin A is delivered to the blood. This process relies on zinc to complete the "mobilization". Finally, vitamin A can form rhodopsin on the retina. At the same time, zinc also has the effect of improving anorexia and partial eclipse. The composition of the invention contains 30 mg zinc. Preferably in the form of zinc oxide, zinc gluconate, zinc chloride, zinc lactate or zinc acetate may also be used, most preferably zinc gluconate. In the total daily dose, zinc is usually 25-50 mg, preferably 30 mg in the composition of the invention.

e) Lutein

Lutein is a carotenoid. Lutein is an antioxidant found in the retina of a healthy eye, the pigment found in the retina. It is mainly in the macular area, plays a role in filtering blue light and has an antioxidant effect. This element cannot be synthesized in the body, so it needs to be supplemented externally. In the total daily dose, lutein is usually 8-20 mg, preferably 10 mg in the composition of the present invention.

f) carotene

After carotene is absorbed by the body, it is converted into vitamin A that can nourish the retina. In the retina, there is a cell "rhodopsin" that regulates the brightness of the retina. Its important component is vitamin A, and carotene just contains the vitamin A that our body needs, which can supplement the needs of rhodopsin cells. . Antioxidation is to resist the damage of free radicals to proteins, lipids and nucleic acids in the body. Carotene has significant anti-oxidation function, and its molecular deconstruction contains multiple conjugated double bonds, which can effectively inhibit the activity of free radicals, thereby reducing its damage to cell genetic material and cell membranes. In the total daily dose, carotene is usually 3-5 mg, preferably 3 mg in the composition of the present invention.

The composition of the invention is used in the preparation of medicines and health products for preventing myopia, preventing and treating lens and retinopathy, improving eyesight, relieving asthenopia, dry eye syndrome or nourishing and strengthening the brain. This product achieves the functions of preventing myopia, improving eyesight and relieving visual fatigue through scientifically and rationally supplementing the necessary trace elements in the body. It can be widely applied to all groups of people, especially the following groups:

a) People with poor eyesight, such as pseudomyopia, myopia, hyperopia, astigmatism, amblyopia, etc.;

b) Computer operators, such as accountants, designers, scientific researchers, secretaries, teachers and other long-term, close-up eye workers; visual fatigue, dry eye patients

c) the elderly.

Advantages of the present invention:

The composition of the invention has the function of protecting visual cells to protect eyesight, can prevent visual fatigue, myopia and treat lens and retinopathy, can be used as a supplement with the effect of invigorating the brain, and is also a health care product for pregnant women. The composition can play an important role in the prevention and treatment of poor vision, myopia, and the rehabilitation and prevention of retinopathy.

The composition of the invention is a scientific and targeted supplement, which has obvious health care functions for eyes and brain, and is of great significance for maintaining, stabilizing and recovering lens and retinal functions.

Detailed ways

In the total daily dose, the composition of the present invention preferably consists of:

Example 1

The composition for protecting eyesight comprises: 30 μg of chromium, 50 μg of selenium, 300 mg of docosahexaenoic acid (DHA), 30 mg of zinc, 10 mg of lutein, and 3 mg of carotene.

Example 2

The composition for protecting eyesight comprises: 25 μg of chromium, 60 μg of selenium, 250 mg of docosahexaenoic acid (DHA), 40 mg of zinc, 8 mg of lutein, and 5 mg of carotene.

Example 3

The composition for protecting eyesight is composed of 35 μg of chromium, 40 μg of selenium, 320 mg of docosahexaenoic acid (DHA), 20 mg of zinc, 15 g of lutein and 3 mg of carotene.

Example 4

The composition for protecting eyesight is composed of 25 μg of chromium, 55 μg of selenium, 350 mg of docosahexaenoic acid (DHA), 50 mg of zinc, 20 mg of lutein and 4 mg of carotene.

Example 5

The composition for protecting eyesight comprises: 32 μg of chromium, 45 μg of selenium, 280 mg of docosahexaenoic acid (DHA), 35 mg of zinc, 12 mg of lutein, and 5 mg of carotene.

According to the constitution of composition among the embodiment 1-5, make soft capsule respectively.

Divide the experimental population into 5 groups, 20-30 people in each group. The experimental population includes people with poor eyesight, such as pseudomyopia, myopia, hyperopia, astigmatism, etc.; computer operators, such as accountants, designers, scientific researchers, secretaries, teachers Etc. long-term, short-distance eye workers; and the elderly, respectively take the medicines of the composition components of Embodiment 1-5, one soft capsule per day, and take 30 days as a course of treatment. The experimental results are shown in Table 1-3.

The results of the treatment of more than 100 experimental populations show that the composition of the present invention can prevent myopia, prevent and treat lens and retinopathy, improve visual acuity significantly, and the effective rate is 95%, and the total effective rate for alleviating visual fatigue and dry eye 100% (recovery and improvement of vision).

It can be seen that the medicine and health products prepared by using the composition of the present invention have obvious effects in preventing myopia, preventing and treating lens and retinopathy, improving eyesight, relieving asthenopia, dry eye, or nourishing and strengthening the brain. efficient.

Table 1 Improvement of myopic vision

Table 2 hypermetropia visual acuity improvement

Table 3 Improvement of other symptoms

Number of experimenters Symptoms before treatment Condition after treatment Efficient 20 people visual fatigue, tears Eye fatigue relief 95% 20 people blurred vision Improved eyesight and gradually clearer vision 95% 20 people dry eye syndrome Symptoms of dry eyes relieved or disappeared 95%

Claims (6)

1. A composition for protecting eyesight, characterized in that: it is made up of chromium, selenium, docosahexaenoic acid, zinc, lutein and carotene. 2. The composition for protecting eyesight according to claim 1, characterized in that: the composition by mass consists of: 25×10 ^-3 -35×10 ^{-3 parts of chromium, 40×10 -3 parts} of selenium 60×10 ^-3 parts, 250-350 parts of docosahexaenoic acid (DHA), 20-50 parts of zinc, 8-20 parts of lutein, 3-5 parts of carotene. 3. The composition for protecting eyesight according to claim 2, characterized in that: the composition in parts by mass is preferably: 30×10 ^-3 parts of chromium, 50×10 ^-3 parts of selenium, docosahexa Dienoic acid (DHA) 300 parts, zinc 30 parts, lutein 10 parts, carotene 3 parts. 4. The composition for protecting eyesight according to claim 2, characterized in that: the composition of the composition is preferably: chromium 25-35 μg, selenium 40-60 μg, docosahexaenoic acid (DHA) 250-350mg , Zinc 20-50mg, Lutein 8-20mg, Carotene 3-5mg. 5. The composition for protecting eyesight according to claim 4, characterized in that: the composition of the composition is more preferably: 30 μg of chromium, 50 μg of selenium, 300 mg of docosahexaenoic acid (DHA), 30 mg of zinc, leaf Flavin 10mg, carotene 3mg. 6. according to the composition of protecting eyesight described in any one in claim 1-5, in preparation prevention myopia, prevention and treatment lens, retinopathy, improve eyesight, alleviate asthenopia or in the medicine and the health product of invigorating the brain Applications.