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CN119819388A - Urine collection device for laboratory mice - Google Patents

Urine collection device for laboratory mice Download PDF

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Publication number
CN119819388A
CN119819388A CN202510030368.0A CN202510030368A CN119819388A CN 119819388 A CN119819388 A CN 119819388A CN 202510030368 A CN202510030368 A CN 202510030368A CN 119819388 A CN119819388 A CN 119819388A
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CN
China
Prior art keywords
filter cartridge
primary filter
top cover
secondary filter
filter cylinder
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Pending
Application number
CN202510030368.0A
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Chinese (zh)
Inventor
杨双竹
王彦君
陈琰
康静
张丰恺
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Jilin University
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Jilin University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jilin University filed Critical Jilin University
Priority to CN202510030368.0A priority Critical patent/CN119819388A/en
Publication of CN119819388A publication Critical patent/CN119819388A/en
Pending legal-status Critical Current

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Abstract

The application provides an experimental mouse urine collecting device which comprises a top cover, a primary filter cylinder, a secondary filter cylinder and a connecting cylinder, wherein the secondary filter cylinder is placed in the connecting cylinder, the primary filter cylinder is placed in the secondary filter cylinder, the top cover covers the top of the primary filter cylinder, the top cover comprises a top cover bottom and a top cover side wall, the top cover side wall and the top cover bottom are integrally formed into a hollow cylinder structure, the primary filter cylinder comprises a primary filter cylinder side wall and a primary filter cylinder bottom screen, the primary filter cylinder bottom screen is installed at the bottom end of the primary filter cylinder, and the aperture of the primary filter cylinder bottom screen is 2mm. The application has simple structure and low cost, can repeatedly perform high temperature and high pressure, can replace each part independently or perform subtraction according to the experimental requirement, can improve the urine collection efficiency of the experimental mice and reduce the experimental cost.

Description

Urine collection device for laboratory mice
Technical Field
The application relates to the technical field of experimental tools, in particular to an experimental mouse urine collecting device.
Background
White rats are the most common experimental animals, accounting for more than 90% of the experimental animals. It has very wide application. Medicine, vaccine and biological medicine production, surgical operation practice exercise, quality inspection and safety evaluation of new medicine and food and medicine, research of life science and the like are all independent of the contribution of the experimental white mouse, so that the white mouse is a difficult person for human beings, a living reagent for scientific research, and the application of the experimental white mouse is very wide. Medicine, vaccine and biological medicine production, surgical practice exercise, quality inspection and safety evaluation of new medicines, foods and medicines, life science research and the like are all free from the contribution of experimental white rats.
In the experimental process, the urine of the experimental mouse needs to be collected, and the main function of the urine collector of the experimental mouse is to effectively collect urine samples discharged by the experimental mouse. The urine sample is important for subsequent biochemical analysis, drug metabolism research and other experimental analysis, and according to analysis of the collected urine sample, physiological indexes of the experimental mice, such as renal function, electrolyte balance, metabolism condition and the like, can be monitored
The current laboratory mouse urine collector structure is complicated, can't carry out multistage filtration to urine after collecting, influences subsequent experimental effect, consequently, need improve.
Disclosure of Invention
The application provides a urine collection device for an experimental mouse, which solves the problems of single structure and high experimental cost of the device in the prior art, realizes repeated high temperature and high pressure, can realize independent replacement of each part or reduce the arrangement according to experimental needs, can improve the urine collection efficiency of the experimental mouse, and reduces the experimental cost.
The application provides an experimental mouse urine collecting device, which comprises a top cover, a primary filter cylinder, a secondary filter cylinder and a connecting cylinder, wherein the top cover is arranged on the top cover;
The secondary filter cartridge is placed in the connecting cartridge;
The primary filter cartridge is placed in a secondary filter cartridge;
the top cover covers the top of the primary filter cartridge.
Preferably, the top cover comprises a top cover bottom and a top cover side wall, and the top cover side wall and the top cover bottom are integrally formed into a hollow cylinder structure.
Preferably, the primary filter cartridge comprises a primary filter cartridge sidewall and a primary filter cartridge bottom screen mounted to the primary filter cartridge bottom end, the primary filter cartridge bottom screen having a pore size of 2mm.
Preferably, the secondary filter cartridge comprises a secondary filter cartridge sidewall and a secondary filter cartridge bottom screen mounted to the secondary filter cartridge bottom end, the secondary filter cartridge bottom screen aperture being 2mm.
Preferably, the diameters of the primary filter cartridge, the secondary filter cartridge and the engagement cartridge are sequentially increased.
Preferably, the top cover, the primary filter cartridge, the secondary filter cartridge and the connecting cartridge are all integrally formed thickened high-temperature and high-pressure resistant borosilicate glass.
Preferably, the high borosilicate glass component comprises 3%-6%Al2O3、10%-12%B2O3、4%-7%Na2O、1%-3%K2O、1%-2%Li2O、0.1%-1%CaO、0.2%-1.5%BaO、0.1%-0.6%ZnO, percent of SiO by weight 2.
Preferably, a method of using a laboratory mouse urine collection device comprises the steps of:
A. the collected urine of the laboratory mice flows into a primary filter cylinder, is preliminarily filtered by a screen mesh at the bottom of the primary filter cylinder and flows into a secondary filter cylinder below;
B. The urine after primary filtration is filtered again through the screen mesh at the bottom of the secondary filter cartridge;
C. the urine after secondary filtration flows into the connecting cylinder below, so that the urine of the laboratory mouse is collected after filtration.
The beneficial effects are that:
(1) The invention has simple structure and low cost, can repeatedly perform high temperature and high pressure, can replace each part independently or perform subtraction according to the experimental requirement, can improve the urine collection efficiency of the experimental mice and reduce the experimental cost.
(2) In the invention, the top cover, the primary filter cartridge, the secondary filter cartridge and the connecting cartridge are all integrally formed thickened high-temperature and high-pressure resistant high borosilicate glass, and all parts are connected by gravity, so that the experiment convenience is improved.
(3) The high borosilicate glass adopted in the invention has good chemical durability and hydrolytic resistance, high overall hardness and high strength, is not easy to crack, and prolongs the service life of the device.
The foregoing description is only an overview of the technical solutions of the embodiments of the present application, and may be implemented according to the content of the specification, so that the technical means of the embodiments of the present application can be more clearly understood, and the following specific embodiments of the present application are given for clarity and understanding.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present application, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of the structure of the present invention;
FIG. 2 is a schematic view of the top cover structure of the present invention;
FIG. 3 is a schematic view of a primary filter cartridge of the present invention;
FIG. 4 is a schematic view of a secondary filter cartridge according to the present invention;
FIG. 5 is a schematic view of a connecting cylinder according to the present invention;
Reference numerals illustrate the top cover side wall 101, top cover bottom 102, primary filter cartridge side wall 201, primary filter cartridge bottom screen 202, secondary filter cartridge side wall 301, secondary filter cartridge bottom screen 302, and engagement cartridge 401.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present application more apparent, the technical solutions of the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present application, and it is apparent that the described embodiments are some embodiments of the present application, but not all embodiments of the present application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs, the terms used in the description of this application are for the purpose of describing particular embodiments only and are not intended to be limiting of the application, and the terms "comprising" and "having" and any variations thereof in the description of this application and the claims and drawings are intended to cover non-exclusive inclusions.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the application. The appearances of the phrase "an embodiment" in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those of skill in the art will explicitly and implicitly appreciate that the embodiments described herein may be combined with other embodiments.
The directional terms appearing in the following description are those directions shown in the drawings and do not limit the specific structure of the application. For example, in the description of the present application, the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present application and simplifying the description, and do not indicate or imply that the device or element being referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the present application.
Further, expressions of directions indicated for explaining the operation and constitution of the respective members of the present embodiment, such as the X direction, the Y direction, and the Z direction, are not absolute but relative, and although these indications are appropriate when the respective members are in the positions shown in the drawings, when these positions are changed, these directions should be interpreted differently to be changed correspondingly.
Furthermore, the terms first, second and the like in the description and in the claims or in the above-described figures, are used for distinguishing between different objects and not for describing a particular sequential order, and may be used to improve one or more of these features either explicitly or implicitly.
In the description of the present application, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and for example, the terms "connected" or "connected" of a mechanical structure may refer to a physical connection, for example, a physical connection may be a fixed connection, for example, a fixed connection by a fixing element, for example, a screw, a bolt, or other fixing element, a physical connection may be a removable connection, for example, a mutually snap-fit or snap-fit connection, and a physical connection may be an integral connection, for example, a welded, bonded, or integrally formed connection. The specific meaning of the above terms in the present application will be understood in specific cases by those of ordinary skill in the art.
In order to make the person skilled in the art better understand the solution of the present application, the technical solution of the embodiment of the present application will be clearly and completely described below with reference to the accompanying drawings.
Referring to fig. 1-5, the application discloses a laboratory mouse urine collection device, which comprises a top cover, a primary filter cartridge, a secondary filter cartridge and a connecting cartridge 401;
the secondary filter cartridge is placed in the adapter cartridge 401;
The primary filter cartridge is placed in a secondary filter cartridge;
the top cover covers the top of the primary filter cartridge.
The top cover comprises a top cover bottom 102 and a top cover side wall 101, and the top cover side wall 101 and the top cover bottom 102 are integrally formed to form a hollow cylinder structure.
The primary filter cartridge comprises a primary filter cartridge sidewall 201 and a primary filter cartridge bottom screen 202, the primary filter cartridge bottom screen 202 is mounted at the bottom end of the primary filter cartridge, and the primary filter cartridge bottom screen 202 has a pore size of 2mm. The screen cloth of primary cartridge filter bottom carries out preliminary filtration to urine, gets rid of partial impurity in the urine.
The secondary filter cartridge comprises a secondary filter cartridge sidewall 301 and a secondary filter cartridge bottom screen 302, the secondary filter cartridge bottom screen 302 being mounted to the secondary filter cartridge bottom end, the secondary filter cartridge bottom screen 302 having a pore size of 2mm. The screen cloth at the bottom of the secondary filter cylinder filters urine again to further remove impurity components in the urine.
In the invention, the diameters of the primary filter cylinder, the secondary filter cylinder and the connecting cylinder are sequentially increased, and the top cover, the primary filter cylinder, the secondary filter cylinder and the connecting cylinder are all integrally formed thickened high-temperature and high-pressure resistant high borosilicate glass, and all parts are connected by gravity, so that the experiment convenience is improved.
In addition, in the invention, the high borosilicate glass comprises 3%-6%Al2O3、10%-12%B2O3、4%-7%Na2O、1%-3%K2O、1%-2%Li2O、0.1%-1%CaO、0.2%-1.5%BaO、0.1%-0.6%ZnO, parts of SiO 2. as the rest in weight proportion, and the adopted high borosilicate glass has good chemical durability and hydrolytic resistance, has high overall hardness and high strength, is not easy to crack, and prolongs the service life of the device.
The application method of the invention comprises the following steps:
A. the collected urine of the laboratory mice flows into a primary filter cylinder, is preliminarily filtered by a screen mesh at the bottom of the primary filter cylinder and flows into a secondary filter cylinder below;
B. The urine after primary filtration is filtered again through the screen mesh at the bottom of the secondary filter cartridge;
C. the urine after secondary filtration flows into the connecting cylinder below, so that the urine of the laboratory mouse is collected after filtration.
In conclusion, the invention has simple structure and low cost, can repeatedly perform high temperature and high pressure, can replace each part independently or perform subtraction according to experimental needs, can improve the urine collection efficiency of the experimental mice, and reduces the experimental cost.
While the application has been described in detail with reference to the foregoing embodiments, it will be understood by those skilled in the art that the foregoing embodiments may be modified or equivalents may be substituted for some of the features thereof, and that the modifications or substitutions do not depart from the spirit and scope of the embodiments of the application.

Claims (8)

1.一种实验鼠尿液收集装置,其特征在于,包括顶盖、初级过滤筒、次级过滤筒和衔接筒(401);1. A urine collection device for experimental mice, characterized in that it comprises a top cover, a primary filter cartridge, a secondary filter cartridge and a connection cartridge (401); 所述次级过滤筒放入衔接筒(401)内;The secondary filter cartridge is placed in the connecting cartridge (401); 所述初级过滤筒放入次级过滤筒内;The primary filter cartridge is placed in the secondary filter cartridge; 所述顶盖盖于初级过滤筒顶部。The top cover is placed on the top of the primary filter cartridge. 2.根据权利要求1所述的一种实验鼠尿液收集装置,其特征在于,所述顶盖包括顶盖底(102)和顶盖侧壁(101),所述顶盖侧壁(101)与顶盖底(102)一体成型呈中空圆柱体结构。2. An experimental mouse urine collection device according to claim 1, characterized in that the top cover includes a top cover bottom (102) and a top cover side wall (101), and the top cover side wall (101) and the top cover bottom (102) are integrally formed into a hollow cylindrical structure. 3.根据权利要求1所述的一种实验鼠尿液收集装置,其特征在于,所述初级过滤筒包括初级过滤筒侧壁(201)和初级过滤筒底部筛网(202),所述初级过滤筒底部筛网(202)安装于初级过滤筒底端,所述初级过滤筒底部筛网(202)孔径为2mm。3. An experimental mouse urine collection device according to claim 1, characterized in that the primary filter cartridge comprises a primary filter cartridge side wall (201) and a primary filter cartridge bottom screen (202), the primary filter cartridge bottom screen (202) is installed at the bottom end of the primary filter cartridge, and the aperture of the primary filter cartridge bottom screen (202) is 2 mm. 4.根据权利要求1所述的一种实验鼠尿液收集装置,其特征在于,所述次级过滤筒包括次级过滤筒侧壁(301)和次级过滤筒底部筛网(302),所述次级过滤筒底部筛网(302)安装于次级过滤筒底端,所述次级过滤筒底部筛网(302)孔径为2mm。4. An experimental mouse urine collection device according to claim 1, characterized in that the secondary filter cartridge comprises a secondary filter cartridge side wall (301) and a secondary filter cartridge bottom screen (302), the secondary filter cartridge bottom screen (302) is installed at the bottom end of the secondary filter cartridge, and the aperture of the secondary filter cartridge bottom screen (302) is 2 mm. 5.根据权利要求1所述的一种实验鼠尿液收集装置,其特征在于,所述初级过滤筒、次级过滤筒和衔接筒的直径依次增大。5. The experimental mouse urine collection device according to claim 1 is characterized in that the diameters of the primary filter cylinder, the secondary filter cylinder and the connecting cylinder increase sequentially. 6.根据权利要求1所述的一种实验鼠尿液收集装置,其特征在于,所述顶盖、初级过滤筒、次级过滤筒和衔接筒均为一体成型的加厚耐高温高压的高硼硅玻璃。6. The experimental mouse urine collection device according to claim 1 is characterized in that the top cover, primary filter cartridge, secondary filter cartridge and connecting cartridge are all integrally formed thickened high-temperature and high-pressure resistant high borosilicate glass. 7.根据权利要求6所述的一种实验鼠尿液收集装置,其特征在于,所述高硼硅玻璃组分按重量比例包括3%-6%Al2O3、10%-12%B2O3、4%-7%Na2O、1%-3%K2O、1%-2%Li2O、0.1%-1%CaO、0.2%-1.5%BaO、0.1%-0.6%ZnO,余量为SiO27. A laboratory mouse urine collection device according to claim 6, characterized in that the high borosilicate glass component comprises, by weight, 3%-6% Al2O3 , 10 %-12% B2O3 , 4 %-7% Na2O , 1%-3% K2O , 1%-2% Li2O , 0.1%-1% CaO, 0.2%-1.5% BaO, 0.1%-0.6% ZnO, and the balance is SiO2 . 8.实现权利要求1所述的一种实验鼠尿液收集装置的使用方法,其特征在于,其使用方法包括以下步骤:8. A method for using the experimental mouse urine collection device according to claim 1, characterized in that the method comprises the following steps: A、收集的实验鼠尿液流入初级过滤筒内,经过初级过滤筒底部筛网初步过滤后流入下方的次级过滤筒内;A. The collected urine of experimental mice flows into the primary filter cylinder, and then flows into the secondary filter cylinder below after being initially filtered by the screen at the bottom of the primary filter cylinder; B、初级过滤后的尿液经过次级过滤筒底部筛网再次过滤;B. The urine after primary filtration is filtered again through the screen at the bottom of the secondary filter cartridge; C、次级过滤后的尿液流入下方的衔接筒内,实现对实验鼠尿液过滤后收集。C. The urine after secondary filtration flows into the connecting tube below, realizing the collection of urine after filtration of experimental mice.
CN202510030368.0A 2025-01-08 2025-01-08 Urine collection device for laboratory mice Pending CN119819388A (en)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101050057A (en) * 2007-05-09 2007-10-10 盐城市华鸥实业有限公司 Borosillicate glass apparatus
CN202364655U (en) * 2011-12-26 2012-08-08 佳木斯大学 Metabolism cage for rats
CN204219870U (en) * 2014-10-27 2015-03-25 宿迁太合生态园林发展有限公司 A kind of natural pond liquid filter vat
US20170128863A1 (en) * 2015-11-06 2017-05-11 James Hull Water filtration device for purifying water
GB2549732A (en) * 2016-04-26 2017-11-01 Apacor Ltd Filter apparatus and filter device for biological samples
EP3709023A1 (en) * 2019-03-15 2020-09-16 Kuen-Der Yang Devices and methods for isolating matters of interest
CN213266095U (en) * 2020-09-01 2021-05-25 浙江创韵环境科技有限公司 Water quality purification treatment equipment
CN213555588U (en) * 2020-08-31 2021-06-29 徐州医科大学 Urine collection device of db/db mouse

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101050057A (en) * 2007-05-09 2007-10-10 盐城市华鸥实业有限公司 Borosillicate glass apparatus
CN202364655U (en) * 2011-12-26 2012-08-08 佳木斯大学 Metabolism cage for rats
CN204219870U (en) * 2014-10-27 2015-03-25 宿迁太合生态园林发展有限公司 A kind of natural pond liquid filter vat
US20170128863A1 (en) * 2015-11-06 2017-05-11 James Hull Water filtration device for purifying water
GB2549732A (en) * 2016-04-26 2017-11-01 Apacor Ltd Filter apparatus and filter device for biological samples
EP3709023A1 (en) * 2019-03-15 2020-09-16 Kuen-Der Yang Devices and methods for isolating matters of interest
TW202102855A (en) * 2019-03-15 2021-01-16 楊崑德 Devices and methods for isolating matters of interest
CN213555588U (en) * 2020-08-31 2021-06-29 徐州医科大学 Urine collection device of db/db mouse
CN213266095U (en) * 2020-09-01 2021-05-25 浙江创韵环境科技有限公司 Water quality purification treatment equipment

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