CN118986818A - Three-in-one traditional Chinese medicine active toothpaste capable of removing tartar, whitening and deodorizing and preparation method thereof - Google Patents
Three-in-one traditional Chinese medicine active toothpaste capable of removing tartar, whitening and deodorizing and preparation method thereof Download PDFInfo
- Publication number
- CN118986818A CN118986818A CN202411404269.6A CN202411404269A CN118986818A CN 118986818 A CN118986818 A CN 118986818A CN 202411404269 A CN202411404269 A CN 202411404269A CN 118986818 A CN118986818 A CN 118986818A
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- China
- Prior art keywords
- traditional chinese
- chinese medicine
- whitening
- montmorillonite
- toothpaste
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Abstract
The invention provides three-in-one traditional Chinese medicine active toothpaste with the functions of removing dental calculus, whitening and deodorizing and a preparation method thereof. The traditional Chinese medicine active toothpaste comprises the following raw material components: the traditional Chinese medicine composition comprises a traditional Chinese medicine extract, fluorinated montmorillonite powder, a friction agent, a humectant, an adhesive, a sweetener, a flavoring agent, a whitening agent and deionized water. The composition is optimized, the traditional Chinese medicine extract is extracted by distillation to be compounded into the traditional Chinese medicine active toothpaste with good taste, the traditional Chinese medicine extract has the effects of inhibiting bacteria, removing scales and whitening, and the traditional Chinese medicine active toothpaste can remove dental plaque and tartar and freshen breath by compounding the components of the fluorinated montmorillonite powder, the traditional Chinese medicine extract and the like under the effective synergistic effect, so that the three-in-one traditional Chinese medicine active toothpaste with the functions of removing the tartar, whitening and deodorizing is prepared.
Description
Technical Field
The invention relates to the field of toothpaste, in particular to three-in-one traditional Chinese medicine active toothpaste capable of removing tartar, whitening and deodorizing and a preparation method thereof.
Background
In daily life, if the oral hygiene is bad, there are many bacteria in the oral cavity, which are mixed with proteins in the food and by-products generated during the decomposition process to form an adhesive film called plaque, which adheres to the teeth and the filling material, and if the plaque stays on the teeth and is not removed in time, it is gradually deposited to become calcified into dental calculus. Natural and healthy advocates in the society, and the safety and efficacy of products are greatly concerned. The oral care products are also the same, and the herbal medicines have the advantages of small side effects and high use safety, and become the main stream of market consumption. Most of the components of the toothpaste are friction agents, and the toothpaste mainly acts as an intermediary and acts between the toothbrush and teeth, so that the friction force between the toothbrush and the teeth is enhanced, and the toothbrush is promoted to clean the teeth.
"Book of Rites" carries "chicken singing, salty gargling", which indicates that people have a gargling habit in the Han dynasty. They often put green salt, vinegar and concentrated tea into water to rinse the teeth, and on the one hand, they can also sterilize and disinfect. Modern researches have shown that tea leaves contain chemical substances such as tea polyphenols, tea polysaccharide, theanine, saponin and the like, have the effects of resisting inflammation and sterilizing, contain mineral substances such as fluorine and the like, and have the effects of cleaning teeth and preventing decayed teeth. In Song dynasty, dentifrice appears, and Chinese herbal medicines are mixed in the dentifrice, so that the dentifrice not only can clean teeth and prevent and treat decayed teeth, but also has better curative effect on gingival bleeding. The montmorillonite has the advantages of porous interior, large specific surface area, high surface activity, excellent adsorption capacity and good carrier, and can be quickly combined with dental stains, dental plaque and tartar on the surface of teeth in the application of toothpaste and then discharged together through rinsing.
At present, the toothpaste containing the traditional Chinese medicine composition has single formula, incomplete functionality and insignificant curative effect. The patent with the patent publication number of CN106943327A is a bletilla striata toothpaste and a preparation method thereof, wherein the traditional Chinese medicine composition comprises the following components: the bletilla striata, the dwarf lilyturf tuber, the bamboo leaves, the mint, the chrysanthemum, the pseudo-ginseng, the rangooncreeper fruit and the purslane can play roles of whitening, deodorizing and sterilizing; a patent with publication number of 106619389A is a hyacinth bletilla toothpaste and a preparation process thereof, wherein the traditional Chinese medicine composition comprises the following components: bletilla striata, madder root and borneol. Has halitosis eliminating, hemostatic and antiinflammatory effects; the toothpaste has the problems that the traditional Chinese medicine is thick, difficult to enter, can not remove dental calculus in oral cavity, and has poor effect of improving dental yellow spots. Aiming at the problems existing in the prior art, the toothpaste provided by the application aims to solve the problems that the prior toothpaste can not refresh breath and can not effectively mask halitosis; the whitening effect is not ideal, and the whitening agent has no obvious improvement effect on dental calculus and dental yellow spots.
Disclosure of Invention
The invention aims to: the invention aims to provide three-in-one traditional Chinese medicine active toothpaste capable of removing dental calculus, whitening and deodorizing and a preparation method thereof, which solve the problems that the existing toothpaste can not make breath fresh and can not effectively mask halitosis; the whitening effect is not ideal, and the whitening agent has no obvious improvement effect on dental calculus and dental yellow spots.
The technical scheme of the invention is as follows:
The three-in-one traditional Chinese medicine active toothpaste capable of removing tartar, whitening and deodorizing is characterized by comprising the following components in parts by weight: 15-30 parts of traditional Chinese medicine extract, 1-5 parts of fluorinated montmorillonite powder, 20-35 parts of friction agent, 10-20 parts of humectant, 5-10 parts of adhesive, 2-5 parts of sweetener, 2-8 parts of aromatic, 2-10 parts of whitening agent and 20-50 parts of deionized water.
Further, the mass ratio of the traditional Chinese medicine extract to the fluorinated montmorillonite powder is 3-15: 1.
Further, the raw materials of the traditional Chinese medicine extract comprise: radix Angelicae Dahuricae, poria, glycyrrhrizae radix, flos Gardeniae, coptidis rhizoma, scutellariae radix, fructus Siraitiae Grosvenorii and Carthami flos.
The preparation of the traditional Chinese medicine extract comprises the following steps:
(1) Fully drying dahurian angelica root, white poria, liquorice, gardenia, coptis root, baical skullcap root, grosvenor momordica fruit and safflower, mechanically crushing, weighing dahurian angelica root, white poria, liquorice, gardenia, coptis root, baical skullcap root, grosvenor momordica fruit and safflower, adding a proper amount of ammonia water for soaking for 0.5-1 hour, adding an ethanol solution with the volume fraction of 50-70%, reflux-extracting for 6-8 hours, cooling to room temperature, and filtering to obtain a liquid medicine A and dregs;
(2) Adding water which is 5-10 times of the total mass of the residues in the step (1), stirring and boiling until the solid-liquid volume ratio in the container is 1: 2-5, cooling and filtering to obtain liquid medicine B;
(3) Mixing the liquid medicine A and the liquid medicine B, decocting, and drying to obtain the traditional Chinese medicine extract.
Furthermore, the fluoridized montmorillonite powder takes montmorillonite as a carrier to carry sodium fluoride.
The preparation method of the fluorinated montmorillonite powder comprises the following steps:
(1) Weighing montmorillonite, adding deionized water and ethanol, stirring uniformly, adding ammonia water, and stirring uniformly to obtain montmorillonite aqueous solution;
(2) Adding sodium carbonate into the montmorillonite aqueous solution prepared in the step (1), uniformly stirring, heating, fully reacting, and standing for a period of time to prepare montmorillonite dispersion liquid;
(3) Adding sodium fluoride into the montmorillonite dispersion liquid prepared in the step (2), fully stirring, and drying to obtain the fluorinated montmorillonite powder.
Further, the weight of the sodium carbonate is 10-25% of that of montmorillonite; the temperature rise in the step (2) is 40-50 ℃; the stirring temperature in the step (3) is 0-10 ℃.
Further, the mass ratio of montmorillonite to sodium fluoride is 50-100: 1.
Further, the friction agent is one or a mixture of more of calcium carbonate, calcium hydrophosphate, silicon dioxide and aluminum hydroxide.
Further, the adhesive is one or more of sodium carboxymethyl cellulose, gum arabic and xanthan gum.
Further, the humectant is one or more of glycerin, propylene glycol, castor oil and sorbitol.
Further, the sweetener is one or more of xylitol, aspartame, maltitol and sorbitol.
Further, the aromatic is one or more of peppermint, cyclodextrin and eugenol.
Further, the whitening agent is one or a mixture of more of sodium phytate, sodium hexametaphosphate, sodium tripolyphosphate and titanium dioxide.
The application also discloses a preparation method of the traditional Chinese medicine active toothpaste, which is characterized by comprising the following steps:
Step one: mixing the traditional Chinese medicine extract with the fluorinated montmorillonite powder to obtain a mixture A;
step two: adding the humectant into the mixture A, and uniformly stirring to obtain a mixture B;
step three: adding the friction agent, the adhesive, the whitening agent and the deionized water into the mixture B, and uniformly stirring to obtain a mixture C;
Step four: adding sweetener and aromatic into the mixture C, stirring, and vacuum concentrating to obtain the final product.
In the application, the mechanism of caries prevention of Chinese herbal medicines mainly depends on inhibiting the acid production of streptococcus mutans and the activity of glycosyltransferase so as to achieve the effect of caries prevention, and the antibacterial effect of angelica dahurica, white poria cocos, liquorice, gardenia, coptis chinensis, scutellaria baicalensis, fructus momordicae, safflower and the like on main cariogenic bacteria is remarkable. The application in toothpaste, the montmorillonite is porous, large in specific surface area and high in surface activity, has excellent adsorption performance, can improve the acid-resistant capability of dental tissues in dental treatment, can inhibit acid dissolution of dentin so as to prevent more dentin tubules from opening and promote remineralization of the dentin tubules, and can enhance the adsorption capability of montmorillonite by fixedly carrying sodium fluoride in the montmorillonite, can be quickly combined with dental stains, dental plaque and tartar on the tooth surfaces in the tooth brushing process, and is discharged through rinsing, so that the fluoride attached in the oral cavity is reduced, and the harm to human bodies is reduced; the aromatic cyclodextrin has the effects of eliminating and covering specific odor, can obviously improve the effect of eliminating the oral odor when being applied to toothpaste, and can also relieve bitter taste and improve the taste of the toothpaste; the whitening agent sodium phytate is complexed with tartar components, so that the generation of dental calculus can be avoided or reduced, the tartar can be separated from the surface of teeth, the sodium tripolyphosphate and the sodium hexametaphosphate have the function of adsorbing pigment, the regeneration of the dental calculus is relieved, the components are synergistically enhanced, and the three-in-one traditional Chinese medicine active toothpaste capable of removing the tartar, whitening the teeth, freshening breath is prepared.
The beneficial effects are that:
the invention provides the three-in-one traditional Chinese medicine active toothpaste with the functions of removing dental calculus, whitening and deodorizing, which can refresh breath and effectively mask halitosis; has good tooth whitening effect and can obviously improve dental calculus and dental yellow spot.
Detailed Description
The invention will be described below in connection with specific embodiments. The following examples are illustrative of the present invention and are not intended to limit the present invention. Other combinations and various modifications within the spirit of the invention may be made without departing from the spirit or scope of the invention.
Sodium fluoride is purchased from the chemical industry Co.Ltd, and montmorillonite is purchased from the new material science Co.Ltd; the chemical reagents used in the invention are all common commercial analytical pure unless specified.
Extract of traditional Chinese medicine:
(1) Fully drying and mechanically crushing dahurian angelica root, white poria, liquorice, gardenia, coptis, baical skullcap root, grosvenor momordica fruit and safflower, weighing 20g of each of the dahurian angelica root, the white poria, the liquorice, the gardenia, the coptis, the baical skullcap root, the grosvenor momordica fruit and the safflower, adding 10ml of 20% ammonia water for soaking for 1 hour, adding 500ml of 70% ethanol solution, carrying out reflux extraction for 6 hours, cooling to room temperature, and filtering to obtain liquid medicine A and dregs;
(2) Adding 500ml of water into 160g of the dregs in the step (1), stirring and boiling until the solid-liquid volume ratio in the container is 1:2, filtering after cooling to obtain liquid medicine B;
(3) Mixing 100g of medicine liquid A and 100g of medicine liquid B, decocting at 50 ℃ for 1h, and vacuum drying to obtain the traditional Chinese medicine extract. Preparation of fluorinated montmorillonite powder A:
(1) Weighing 500g of montmorillonite, adding 500ml of deionized water and 500ml of ethanol, uniformly stirring, adding 5ml of ammonia water with the mass concentration of 25%, and uniformly stirring to obtain a montmorillonite aqueous solution;
(2) Adding 125g of sodium carbonate into the montmorillonite aqueous solution prepared in the step (1), uniformly stirring, heating to 50 ℃, and fully reacting for 2 hours to prepare a montmorillonite dispersion liquid;
(3) 10g of sodium fluoride is added into the montmorillonite dispersion liquid prepared in the step (2), the mixture is stirred for 1h at 10 ℃, and the mixture is dried in vacuum at 20 ℃ to prepare the fluorinated montmorillonite powder A.
Preparation of fluorinated montmorillonite powder B:
(1) Weighing 1200g of montmorillonite, adding 1200ml of deionized water and 1200ml of ethanol, uniformly stirring, adding 12ml of ammonia water with the mass concentration of 25%, and uniformly stirring to obtain a montmorillonite aqueous solution;
(2) Adding 125g of sodium carbonate into the montmorillonite aqueous solution prepared in the step (1), uniformly stirring, heating to 50 ℃, and fully reacting for 2 hours to prepare a montmorillonite dispersion liquid;
(3) 10g of sodium fluoride is added into the montmorillonite dispersion liquid prepared in the step (2), the mixture is stirred for 1h at 10 ℃, and the mixture is dried in vacuum at 20 ℃ to prepare the fluorinated montmorillonite powder B.
Preparation of fluorinated montmorillonite powder C:
(1) Weighing 250g of montmorillonite, adding 250ml of deionized water and 250ml of ethanol, uniformly stirring, adding 2.5ml of ammonia water with the mass concentration of 25%, and uniformly stirring to obtain a montmorillonite aqueous solution;
(2) Adding 62.5g of sodium carbonate into the montmorillonite aqueous solution prepared in the step (1), uniformly stirring, heating to 50 ℃, and fully reacting for 2 hours to prepare a montmorillonite dispersion liquid;
(3) 10g of sodium fluoride is added into the montmorillonite dispersion liquid prepared in the step (2), the mixture is stirred for 1h at 10 ℃, and the mixture is dried in vacuum at 20 ℃ to prepare the fluorinated montmorillonite powder C.
Preparation of fluorinated montmorillonite powder D:
weighing 500g of montmorillonite and 10g of sodium fluoride, adding 500ml of deionized water and 500ml of ethanol, stirring uniformly, and vacuum drying to obtain fluorinated montmorillonite powder D.
The preparation method of the traditional Chinese medicine active toothpaste comprises the following steps:
Step one: mixing the traditional Chinese medicine extract with the fluorinated montmorillonite powder to obtain a mixture A;
step two: adding the humectant into the mixture A, and uniformly stirring to obtain a mixture B;
step three: adding the friction agent, the adhesive, the whitening agent and the deionized water into the mixture B, and uniformly stirring to obtain a mixture C;
Step four: adding sweetener and aromatic into the mixture C, stirring, and vacuum concentrating to obtain the final product.
Examples 1 to 6
According to the preparation method of the traditional Chinese medicine active toothpaste, table 1 is the ingredient table of the traditional Chinese medicine active toothpaste of examples 1-6.
TABLE 1
Comparative examples 1 to 7
According to the preparation method of the traditional Chinese medicine active toothpaste, table 2 is the ingredient table of the traditional Chinese medicine active toothpaste of comparative examples 1-7.
TABLE 2
Performance test:
test 1: the sterilization effect test method comprises the following steps:
Preparation of bacterial suspension: culturing the staphylococcus strain and the streptococcus mutans strain for 4 hours, and preparing bacterial suspension with the concentration of 1 multiplied by 10 to 5CFU/ml by using sterile physiological saline;
and (3) grouping setting: a control group (without toothpaste) and an experimental group (with the addition of the traditional Chinese medicine active toothpastes of examples 1 to 6 and comparative examples 1 to 7) were set;
Treatment experimental group: to the experimental group, 0.1 toothpaste and 10mL bacterial suspension were added, mixed well and allowed to act at 25 ℃ for 1 hour.
Dilution and coating: after the action time is over, respectively diluting an experimental group and a control group by 10 times, and then coating diluted bacterial liquid on a solid culture medium plate;
culturing: the plate was placed in an incubator at 37℃with 60% relative air humidity for 24 hours;
counting: after incubation, colonies on the plates were counted;
Data analysis: the bacterial colony numbers of the experimental group and the control group were compared, and the antibacterial rate (%) of the toothpaste against bacteria was calculated, thereby evaluating the antibacterial effect of the toothpaste.
Test 2: sensory test method: selecting 60 patients frequently suffering from dental calculus and various oral problems as trial objects, randomly dividing the patients into 12 groups, using the traditional Chinese medicine active toothpastes of examples 1-6 and comparative examples 1-7 respectively for 5 persons in each group, wherein the using times are once in the morning, the evening and the using period are 2 weeks, and then scoring the used traditional Chinese medicine active toothpastes, wherein the scoring items are as follows: the product has good taste, tartar removing effect, and breath freshening effect; the scoring values were 0-5, where 0 indicates substantial inefficiency/very dissatisfaction and 5 indicates significant/very satisfactory results, as shown in table 3.
Table 3: test results table
From the data, the traditional Chinese medicine active toothpaste with the functions of removing dental calculus, whitening and deodorizing prepared by the invention contains the traditional Chinese medicine extract and the fluorinated montmorillonite powder, and the effects of removing dental calculus, whitening and deodorizing of the toothpaste are mutually and synergistically enhanced, and the specific characteristics are that the proportion of the traditional Chinese medicine extract to the fluorinated montmorillonite powder is unreasonable, compared with the examples 1-3, so that the degerming rate of the prepared traditional Chinese medicine active toothpaste is reduced, and the using effect is weakened; as can be seen from comparison of example 5 with example 2, when the content of montmorillonite and sodium fluoride in the used fluorinated montmorillonite powder is not reasonable, the tartar removal effect of the prepared traditional Chinese medicine active toothpaste is reduced; comparison of example 6 with example 2 shows that when the content ratio of montmorillonite to sodium fluoride in the used fluorinated montmorillonite powder is too small, the tartar removal effect of the prepared traditional Chinese medicine active toothpaste is reduced; comparison of comparative example 1 with example 1 shows that the degerming rate of the traditional Chinese medicine active toothpaste prepared by changing the montmorillonite powder into sodium fluoride is poor, and the use taste is poor; comparison of comparative example 2 with example 2 shows that changing the powder of the fluoridated montmorillonite into montmorillonite can result in poor degerming effect and weakened tartar removing effect of the prepared traditional Chinese medicine active toothpaste, and the expected effect can not be achieved; as can be seen from comparison of comparative example 3 and example 3, the traditional Chinese medicine active toothpaste prepared without adding the fluorinated montmorillonite powder has poor use effect, scale removal capability and poor whitening effect; comparative example 4 and example 3 show that the same components are adopted, and the traditional Chinese medicine active toothpaste prepared without adding the traditional Chinese medicine extract has poor bacteria removing effect and poor tartar removing capability; comparison of comparative example 5 and example 3 shows that the whitening effect and the tartar removing capability of the traditional Chinese medicine active toothpaste prepared by adding small amount of the fluorinated montmorillonite powder can not reach the expected effect; as is clear from the comparison between comparative example 6 and example 2, the addition of too much fluorinated montmorillonite powder resulted in poor taste and no desired effect. Comparison of comparative example 7 with example 1 shows that the preparation of the fluorinated montmorillonite powder without sodium carbonate results in poor descaling effect with no expected effect.
The present invention is capable of other and further embodiments and its several details are capable of modification and variation in light of the present invention, as will be apparent to those skilled in the art, without departing from the spirit and scope of the invention as defined in the appended claims.
Claims (10)
1. The three-in-one traditional Chinese medicine active toothpaste capable of removing tartar, whitening and deodorizing is characterized by comprising the following components in parts by weight: 15-30 parts of traditional Chinese medicine extract, 1-5 parts of fluorinated montmorillonite powder, 20-35 parts of friction agent, 10-20 parts of humectant, 5-10 parts of adhesive, 2-5 parts of sweetener, 2-8 parts of aromatic, 2-10 parts of whitening agent and 20-50 parts of deionized water.
2. The three-in-one traditional Chinese medicine active toothpaste with the functions of removing dental calculus, whitening and deodorizing according to claim 1, wherein the mass ratio of the traditional Chinese medicine extract to the fluorinated montmorillonite powder is 3-15: 1.
3. The three-in-one traditional Chinese medicine active toothpaste with the functions of removing tartar, whitening and deodorizing according to claim 1 or 2, wherein the raw materials of the traditional Chinese medicine plant comprise: radix Angelicae Dahuricae, poria, glycyrrhrizae radix, flos Gardeniae, coptidis rhizoma, scutellariae radix, fructus Siraitiae Grosvenorii and Carthami flos.
4. The three-in-one traditional Chinese medicine active toothpaste with the functions of removing dental calculus, whitening and deodorizing according to claim 1, wherein the preparation of the traditional Chinese medicine extract comprises the following steps:
(1) Fully drying dahurian angelica root, white poria, liquorice, gardenia, coptis root, baical skullcap root, grosvenor momordica fruit and safflower, mechanically crushing, weighing dahurian angelica root, white poria, liquorice, gardenia, coptis root, baical skullcap root, grosvenor momordica fruit and safflower, adding a proper amount of ammonia water for soaking for 0.5-1 hour, adding an ethanol solution with the volume fraction of 50-70%, reflux-extracting for 6-8 hours, cooling to room temperature, and filtering to obtain a liquid medicine A and dregs;
(2) Adding water which is 5-10 times of the total mass of the residues in the step (1), stirring and boiling until the solid-liquid volume ratio in the container is 1: 2-5, cooling and filtering to obtain liquid medicine B;
(3) Mixing the liquid medicine A and the liquid medicine B, decocting, and drying to obtain the traditional Chinese medicine extract.
5. The three-in-one traditional Chinese medicine active toothpaste with the functions of removing tartar, whitening and deodorizing according to claim 1 or 2, wherein the fluoridized montmorillonite powder takes montmorillonite as a carrier to carry sodium fluoride.
6. The three-in-one traditional Chinese medicine active toothpaste with the functions of removing dental calculus, whitening and deodorizing according to claim 5, wherein the preparation of the fluorinated montmorillonite powder comprises the following steps:
(1) Weighing montmorillonite, adding deionized water and ethanol, stirring uniformly, adding ammonia water, and stirring uniformly to obtain montmorillonite aqueous solution;
(2) Adding sodium carbonate into the montmorillonite aqueous solution prepared in the step (1), uniformly stirring, heating, fully reacting, and standing for a period of time to prepare montmorillonite dispersion liquid;
(3) Adding sodium fluoride into the montmorillonite dispersion liquid prepared in the step (2), fully stirring, and drying to obtain the fluorinated montmorillonite powder.
7. The three-in-one traditional Chinese medicine active toothpaste with the functions of removing tartar, whitening and deodorizing according to claim 6, wherein the weight of the sodium carbonate is 10-25% of that of montmorillonite; the temperature rise in the step (2) is 40-50 ℃; the stirring temperature in the step (3) is 0-10 ℃.
8. The three-in-one traditional Chinese medicine active toothpaste with the functions of removing dental calculus, whitening and deodorizing according to claim 6, wherein the mass ratio of montmorillonite to sodium fluoride is 50-100: 1.
9. The three-in-one traditional Chinese medicine active toothpaste with the functions of removing dental calculus, whitening and deodorizing according to claim 1, which is characterized in that,
The friction agent is one or more of calcium carbonate, calcium hydrophosphate, silicon dioxide and aluminum hydroxide;
the adhesive is one or more of sodium carboxymethyl cellulose, gum arabic and xanthan gum;
the humectant is one or more of glycerol, propylene glycol, castor oil and sorbitol;
The sweetener is one or more of xylitol, aspartame, maltitol and sorbitol;
The aromatic is one or more of peppermint, cyclodextrin and eugenol;
the whitening agent is one or more of sodium phytate, sodium hexametaphosphate, sodium tripolyphosphate and titanium dioxide.
10. The preparation method of the three-in-one traditional Chinese medicine active toothpaste with the functions of removing tartar, whitening and deodorizing as claimed in any one of claims 1 to 9, which is characterized by comprising the following steps:
Step one: mixing the traditional Chinese medicine extract with the fluorinated montmorillonite powder to obtain a mixture A;
step two: adding the humectant into the mixture A, and uniformly stirring to obtain a mixture B;
step three: adding the friction agent, the adhesive, the whitening agent and the deionized water into the mixture B, and uniformly stirring to obtain a mixture C;
Step four: adding sweetener and aromatic into the mixture C, stirring, and vacuum concentrating to obtain the final product.
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| CN202411404269.6A CN118986818A (en) | 2024-10-09 | 2024-10-09 | Three-in-one traditional Chinese medicine active toothpaste capable of removing tartar, whitening and deodorizing and preparation method thereof |
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