CN118986408A

CN118986408A - Transcranial ultrasound application device

Info

Publication number: CN118986408A
Application number: CN202310572635.8A
Authority: CN
Inventors: 李帅; 佘仲君; 郑永平
Original assignee: Hong Kong Polytechnic University HKPU
Current assignee: Hong Kong Polytechnic University HKPU
Priority date: 2023-05-19
Filing date: 2023-05-19
Publication date: 2024-11-22

Abstract

The present application relates to the technical field of medical devices, and discloses a transcranial ultrasound application device. The transcranial ultrasound application device includes a head frame body, a first mounting assembly, and a first detection assembly; the head frame body includes a fixing assembly and an annular guide rail, the fixing assembly is connected to the annular guide rail and is used to set the annular guide rail on the user's head; the first mounting assembly includes a first mounting frame and a first stage, the first mounting frame is slidably connected to the annular guide rail and is used to install the first stage, the first mounting frame can slide along the annular guide rail to drive the first stage to rotate around the user's head; the first detection assembly includes a depth camera and a first ultrasound probe arranged on the first stage, the depth camera is used to scan the outer contour of the user's head and determine the position of the skull acoustic window. The transcranial ultrasound application device provided in the present application can solve the technical problems of high difficulty and inaccurate positioning of the skull acoustic window in the related technology by designing the annular guide rail and the first detection assembly.

Description

Transcranial ultrasound application device

Technical Field

The application relates to the technical field of medical appliances, in particular to a transcranial ultrasonic application device.

Background

With the development of ultrasound technology, transcranial ultrasound applications have become an integral part of clinical diagnosis and treatment. Transcranial ultrasound (TRANSCRANIAL SONOGRAPHY, TCS), displaying brain internal structures using ultrasound gray scale images; transcranial doppler (TRANSCRANIAL DOPPLER, TCD) and transcranial color doppler (TRANSCRANIAL COLOR DOPPLER, TCCD) are one non-invasive method of cerebrovascular disease detection using the ultrasonic doppler effect to detect the hemodynamic and blood flow physiological parameters of the main intracranial artery. These techniques all use the lower frequency range of the emitted frequency (1-3.5 MHz) to allow the ultrasonic beam to penetrate the thinner parts of the skull. In contrast, pulse Doppler techniques are used to obtain the Doppler shift of blood flow in the intracranial artery to obtain the intracranial hemodynamic parameters to reflect the functional state of the cerebral blood vessel.

Imaging-related ultrasound applications typically utilize naturally weakened locations of the skull as detection acoustic windows, such as temporal windows, ocular windows, occipital windows, and the like. In the prior art, the position of the skull acoustic window is mostly judged by subjective experience of an operator, ultrasonic diagnosis and even stimulation are carried out by operating ultrasonic equipment after the judgment is finished, the process has higher requirements on the operator, and the problems of low diagnosis accuracy and low recurrence rate caused by inaccurate positioning of the skull acoustic window are easy to occur.

Disclosure of Invention

The application aims to provide a transcranial ultrasonic application device which is used for solving the technical problems of high difficulty in positioning and inaccurate positioning of a skull acoustic window in the related technology.

To solve the above problems, the present application provides a transcranial ultrasound application device, comprising:

The headstock body comprises a fixing assembly and an annular guide rail, wherein the fixing assembly is connected to the annular guide rail and used for erecting the annular guide rail on the head of a user;

The first installation assembly comprises a first installation frame and a first objective table, wherein the first installation frame is connected with the annular guide rail in a sliding manner and used for installing the first objective table, and the first installation frame can slide along the annular guide rail so as to drive the first objective table to rotate around the circumferential direction of the head of a user;

The first detection assembly comprises a depth camera and a first ultrasonic probe, wherein the depth camera and the first ultrasonic probe are arranged on the first objective table, and the depth camera is used for scanning the outer contour of the head of a user and determining the position of a skull sound window.

In one embodiment, the first mounting frame comprises a first bracket and a second bracket which are rotatably connected, an included angle between the first bracket and the second bracket is adjustable, the first bracket is connected with the annular guide rail, and the second bracket is connected with the first objective table.

In one embodiment, the second bracket is a telescopic rod and is adjustable in length.

In one embodiment, the first ultrasonic probe is a single-vibrating-element probe or a multi-vibrating-element probe, the frequency of ultrasonic waves emitted by the first ultrasonic probe is 0.5MHz-20MHz, and the intensity is 1mW/cm ²-3W/cm².

In one embodiment, the first detection assembly further comprises a pressure sensor disposed on the first stage for detecting a contact pressure between the first ultrasonic probe and the head of the user.

In one embodiment, the front end of the first ultrasonic probe is provided with a coupling pad, and ultrasonic waves emitted by the first ultrasonic probe can penetrate through the coupling pad.

In one embodiment, the headstock body further comprises a connecting rod, the connecting rod is erected on the annular guide rail, and two ends of the connecting rod are fixedly connected to the annular guide rail; the transcranial ultrasonic application device further comprises a second installation component and a second detection component, the second installation component comprises a second installation frame and a second objective table, the second installation frame is arranged on the connecting rod and used for installing the second objective table, and the second detection component is arranged on the second objective table and used for conducting ultrasonic stimulation on a target area of the cerebral cortex on the head of a user and acquiring brain electrical signals.

In one embodiment, the second mounting frame comprises a fixing seat and a third support, the fixing seat is arranged on the connecting rod, the third support is arranged on the fixing seat, and the third support is a telescopic rod and has an adjustable length.

In one embodiment, the second detection assembly includes an electrode pad and a second ultrasonic probe.

In one embodiment, the fixing assembly comprises a fixing bracket connected to an arbitrary position of the connecting rod and used for suspending the connecting rod and the annular guide rail.

In one embodiment, the fixing assembly comprises an annular head band and a plurality of support rods, the support rods are arranged at intervals along the circumferential direction of the annular head band, one end of each support rod is connected with the annular head band, the other end of each support rod is connected with the annular guide rail, and the annular head band is used for being worn on the head of a user and used for supporting the annular guide rail.

In one embodiment, the annular head band is of an open structure and has a first end with a first adjustment aperture disposed thereon and a second end with a second adjustment aperture disposed thereon, the first and second adjustment apertures being disposed opposite one another, and both the first and second adjustment apertures being configured with a rack structure;

the fixing assembly further comprises an adjusting knob, the adjusting knob is inserted into the first adjusting hole and the second adjusting hole, the adjusting knob is meshed with the rack structure, and the first end and the second end can be driven to move relatively through rotation of the adjusting knob.

In one embodiment, the inner side wall of the annular guide rail is provided with a plurality of clamping grooves, one end of the supporting rod is fixedly connected with the annular head hoop, the other end of the supporting rod is clamped in the clamping grooves, the number of the clamping grooves is larger than that of the supporting rod, and the installation position of the supporting rod is adjustable.

The scheme provided by the application comprises a headstock body, a first installation component and a first detection component, wherein the headstock body comprises a fixing component and an annular guide rail, the first installation component comprises a first installation frame and a first objective table, the detection component comprises a depth camera and a first ultrasonic probe, when the headstock is used, the annular guide rail can be erected on the head of a user by the fixing component, the depth camera and the first ultrasonic probe are driven by the first installation frame and the first objective table to slide along the annular guide rail, in the process, the depth camera and the first ultrasonic probe rotate around the circumference of the head of the user, three-dimensional reconstruction of the head of the user can be completed, the position of a skull acoustic window can be determined, and after the position of the skull acoustic window is determined, the first ultrasonic probe can be fixed at the position of the skull acoustic window for ultrasonic diagnosis. Therefore, by providing the transcranial ultrasonic application device with the skull acoustic window positioning function, the positioning difficulty of the skull acoustic window in brain ultrasonic operation can be reduced, and the positioning accuracy of the skull acoustic window can be improved.

Drawings

In order to more clearly illustrate the embodiments of the application or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic view of a user's head skull sound window;

FIG. 2 is a schematic diagram of a transcranial ultrasound application device according to a first embodiment of the present application;

FIG. 3 is a schematic view of the transcranial ultrasound application device of FIG. 2 in another state;

FIG. 4 is a schematic view of the transcranial ultrasound application device of FIG. 2 from another perspective;

FIG. 5 is a schematic view of another transcranial ultrasound application device according to a first embodiment of the present application;

FIG. 6 is a schematic diagram of a still further transcranial ultrasound application device according to a first embodiment of the present application;

FIG. 7 is a schematic view of a first mounting assembly of the transcranial ultrasound application device of FIG. 2;

FIG. 8 is a schematic diagram of a first carrier plate and a first detection assembly of the transcranial ultrasound application device of FIG. 2;

FIG. 9 is a schematic diagram of the first carrier plate and the first detection assembly of the transcranial ultrasound application device of FIG. 2 in another view;

fig. 10 is a schematic structural view of a transcranial ultrasound application device according to a second embodiment of the present application;

FIG. 11 is a schematic view of the transcranial ultrasound application device of FIG. 10 from another perspective;

Fig. 12 is a schematic structural view of another transcranial ultrasound application device according to a second embodiment of the present application.

100. Transcranial ultrasound application means;

1. A headstock body; 11. a fixing assembly; 111. an annular head band; 112. a support rod; 113. an adjustment knob; 114. a fixed bracket; 12. an annular guide rail; 13. a connecting rod;

2. A first mounting assembly; 21. a first mounting frame; 211. a first bracket; 212. a second bracket; 22. a first stage; 23. a universal shaft;

3. a first detection assembly; 31. a depth camera; 32. a first ultrasonic probe; 33. a pressure sensor;

41. A coupling pad; 42. a motor;

5. a second mounting assembly; 51. a second mounting frame; 511. a fixing seat; 512. a third bracket; 52. a second stage;

6. and a second detection assembly.

Detailed Description

The present application will be described in further detail with reference to the drawings and examples, in order to make the objects, technical solutions and advantages of the present application more apparent. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the application.

It will be understood that when an element is referred to as being "mounted" or "disposed" on another element, it can be directly or indirectly disposed on the other element. When an element is referred to as being "connected to" another element, it can be directly or indirectly connected to the other element. The terms "upper," "lower," "left," "right," and the like are used for convenience of description based on the orientation or positional relationship shown in the drawings, and do not denote or imply that the devices or elements in question must have a particular orientation, be constructed and operated in a particular orientation, and are therefore not to be construed as limiting of the patent. The terms "first," "second," and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features. The meaning of "a plurality of" is two or more, unless specifically defined otherwise.

Reference in the specification to "one embodiment," "some embodiments," or "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment is included in one or more embodiments of the application. Thus, appearances of the phrases "in one embodiment," "in some embodiments," "in other embodiments," and the like in the specification are not necessarily all referring to the same embodiment, but mean "one or more but not all embodiments" unless expressly specified otherwise. Furthermore, the particular features, structures, or characteristics may be combined in any suitable manner in one or more embodiments.

Embodiment one:

the application provides a transcranial ultrasonic application device which is applied to the field of brain ultrasound and is mainly used for ultrasonic diagnosis.

Referring to fig. 2,3 and 4, a transcranial ultrasound application device 100 includes a headgear body 1, a first mounting assembly 2 and a first detection assembly 3. The headgear body 1 includes a securing assembly 11 and a circular rail 12, the securing assembly 11 being connected to the circular rail 12 and adapted to mount the circular rail 12 to a user's head. The first mounting assembly 2 includes a first mounting frame 21 and a first stage 22, the first mounting frame 21 is slidably connected to the annular rail 12 and is configured to mount the first stage 22, and the first mounting frame 21 is capable of sliding along the annular rail 12 to drive the first stage 22 to rotate circumferentially around the user's head. As shown in fig. 2, 8 and 9, the first detection assembly 3 includes a depth camera 31 and a first ultrasound probe 32 provided on the first stage 22, the depth camera 31 being used to scan the outer contour of the user's head and determine the skull sound window position.

The fixing assembly 11 is worn on the head of a user, and the annular guide rail 12 connected to the fixing assembly 11 can be erected on the head of the user.

The annular guide 12 may be annular, but is not limited thereto, and for example, the annular guide 12 may be an elliptical ring, a square ring, or the like. The annular rail 12 has an inner diameter that is greater than the head circumference of the user so that the annular rail 12 can be mounted on the user's head and spaced therefrom.

The first mounting rack 21 is used for mounting the first objective table 22 and the first detection component 3, and the first mounting rack 21 can slide along the annular guide rail 12, so that the first detection component 3 on the first objective table 22 can be driven to move around the head of a user.

The depth camera 31 is used for 360 ° scanning detection of the user's head to acquire three-dimensional information of the user's head contour and determine the skull sound window position. Specifically, the depth camera 31 includes a light source emitting part for emitting light into a space, and a receiving part for receiving reflected light of a user's head and acquiring image information of the user's head according to the reflected light, and the depth camera 31 can acquire surface details of the user's head and complete three-dimensional reconstruction of the user's head by capturing the image information of the user's head, and determine the position of a skull sound window after the three-dimensional reconstruction is completed. Wherein the cranial sound window includes at least one of a temporal window (as shown in fig. 1 a), an ocular window (as shown in fig. 1 b), and a occipital window (as shown in fig. 1 c).

The first ultrasound probe 32 is used to emit ultrasound waves at the skull sound window for ultrasound stimulation or to acquire ultrasound brain images. In particular, the first ultrasound probe 32 can be used to achieve ultrasound neuromodulation, two-dimensional imaging, or three-dimensional imaging, among others.

The first ultrasound probe 32 also has a positioning effect. Specifically, the first ultrasonic probe 32 emits ultrasonic waves toward the head of the user, and by comparing the attenuation of the emission and reception limit signals, the sound window position can be automatically analyzed and judged. In some cases, to improve the accuracy of the skull window positioning, the window position may be initially determined using the depth camera 31 and then further positioned using the first ultrasound probe 32.

The scheme provided by the application comprises a headstock body 1, a first mounting assembly 2 and a first detection assembly 3, wherein the headstock body 1 comprises a fixing assembly 11 and an annular guide rail 12, the first mounting assembly 2 comprises a first mounting frame 21 and a first objective table 22, the first detection assembly 3 comprises a depth camera 31 and a first ultrasonic probe 32, when in use, the annular guide rail 12 can be erected on a user head by the fixing assembly 11, the depth camera 31 and the first ultrasonic probe 32 can be driven to slide along the annular guide rail 12 by the first mounting frame 21 and the first objective table 22, in the process, the depth camera 31 and the first ultrasonic probe 32 rotate around the circumference of the user head, three-dimensional reconstruction of the user head can be completed, the position of a skull acoustic window can be determined, and after the position of the skull acoustic window is determined, the first ultrasonic probe 32 can be fixed at the position of the skull acoustic window for ultrasonic diagnosis. Thus, by providing the transcranial ultrasound application apparatus 100 with the function of positioning the skull acoustic window, the positioning difficulty of the skull acoustic window in the brain ultrasound operation can be reduced and the positioning accuracy of the skull acoustic window can be improved.

In the solution provided in this embodiment, as shown in fig. 2, 3 and 7, the first mounting frame 21 includes a first bracket 211 and a second bracket 212 rotatably connected, an included angle between the first bracket 211 and the second bracket 212 is adjustable, the first bracket 211 is connected to the annular rail 12, and the second bracket 212 is connected to the first stage 22.

For example, the first bracket 211 is rotatably connected to the second bracket 212 through a fixed shaft, and the second bracket 212 can rotate relative to the first bracket 211 and drive the first stage 22 disposed at an end portion thereof to move.

By adopting the design, the flexibility of the first objective table 22 can be improved and the movable range of the first objective table can be widened by improving the structure of the first installation frame 21, so that the position of the first detection component 3 can be conveniently adjusted in the use process, and the detection precision of the first detection component 3 can be improved.

It will be appreciated that, in some embodiments, the first mounting frame 21 includes only the first bracket 211, where the first bracket 211 is rotatably connected to the annular rail 12, and the first bracket 211 can slide along the annular rail 12 circumferentially and also rotate in a vertical plane relative to the annular rail 12, so as to implement the position adjustment of the first detection assembly 3, which may be specifically designed according to practical situations, and is not limited herein.

In the solution provided in the present embodiment, the second bracket 212 is a telescopic rod and has an adjustable length.

By adopting the design, the movable range of the first objective table 22 is further widened by improving the structure of the second bracket 212, and the first detection component 3 can be close to or far away from the head of a user by adjusting the telescopic length of the second bracket 212 in the use process, so that the detection precision of the first detection component 3 can be further improved, and the applicability of the transcranial ultrasonic application device 100 is improved.

Further, the telescopic structure of the second bracket 212 is not unique. Alternatively, in some embodiments, second support 212 comprises a sleeved upper rod rotatably coupled to first support 211 and a lower rod slidably coupled to upper rod and coupled at one end to first stage 22; alternatively, in some embodiments, the second bracket 212 may be configured as a scissor-type telescopic bracket, which may be specifically configured according to practical situations, and is not limited herein.

In the solution provided in this embodiment, as shown in fig. 7, the first stage 22 is connected to the second bracket 212 through a universal shaft 23, and the first stage 22 can rotate relative to the second bracket 212.

By improving the connection structure between the first stage 22 and the second support 212, the angle adjustment of the first stage 22 can be realized, and the positional relationship between the first detection component 3 and the head of the user can be conveniently adjusted.

In the embodiment provided by the application, the annular guide rail 12 is provided with a sliding block, one end of the first bracket 211 is connected to the sliding block, and the other end is hinged with the second bracket 212. The first bracket 211 may be fixedly connected or rotationally connected with the slider, and may be specifically designed according to practical situations.

In the solution provided in this embodiment, the first ultrasonic probe 32 is a single-vibrating-element probe or a multi-vibrating-element probe, and the frequency of the ultrasonic wave emitted by the first ultrasonic probe 32 is 0.5MHz-20MHz, and the intensity is 1mW/cm ²-3W/cm². For example, the first ultrasound probe 32 may be selected from the Olympus model A303S-SU Shan Zhenyuan probe.

Wherein, the single-vibrator probe can be applied to ultrasonic nerve regulation (stimulation) and transcranial Doppler; the multi-vibrating element probe can be applied to ultrasonic brain imaging, including transcranial B ultrasound and color ultrasound of gray level images.

In the solution provided in this embodiment, as shown in fig. 7, the first detecting assembly 3 further includes a pressure sensor 33, where the pressure sensor 33 is disposed on the first stage 22 and is used for detecting the contact pressure between the first ultrasonic probe 32 and the head of the user.

The pressure sensor 33 is disposed at the front end of the first ultrasonic probe 32 or between the first ultrasonic probe 32 and the first stage 22, and specifically may be designed according to the mounting manner of the first ultrasonic probe 32, which is not limited only herein.

When the first ultrasonic probe 32 is used, it is required to be in contact with the skin at the site to be measured by the user, and contact pressure between the first ultrasonic probe 32 and the skin of the user can reflect the contact effect. By providing the pressure sensor 33 on the first stage 22, pressure data can be acquired in real time, and the position of the first ultrasonic probe 32 can be adjusted according to the acquired pressure data information, so as to improve the accuracy of positioning the acoustic window and the ultrasonic diagnostic effect.

In the solution provided in this embodiment, as shown in fig. 8, the front end of the first ultrasonic probe 32 is provided with a coupling pad 41, and the ultrasonic waves emitted by the first ultrasonic probe 32 can penetrate the coupling pad 41.

The coupling pad 41 has a transitional function, and the coupling pad 41 is designed between the first ultrasonic probe 32 and the skin of the user, so that the acoustic impedance difference between the first ultrasonic probe 32 and the skin of the user is reduced, the incidence path and the reflection path of ultrasonic waves are smoother, a clearer ultrasonic pattern can be obtained, and the positioning accuracy of an acoustic window and the ultrasonic diagnosis effect are improved.

The depth camera 31 and the first ultrasonic probe 32 are both disposed on the first stage 22, and the coupling pad 41 covers the front end of the first ultrasonic probe 32 and does not block the depth camera 31.

In the solution provided in this embodiment, as shown in fig. 7 and 8, the first ultrasonic probe 32 is rotatably disposed on the first stage 22 through a rotation shaft, and the first stage 22 is further provided with a motor 42, where the motor 42 is connected to the first ultrasonic probe 32 and is used for driving the first ultrasonic probe 32 to rotate.

The motor 42 may rotate clockwise or counterclockwise and drive the first ultrasound probe 32 to rotate in different directions in a plane parallel to the first stage 22 to adjust the first ultrasound probe 32 to an optimal angle of incidence or scan plane for high precision three-dimensional ultrasound imaging.

With the above design, the flexibility of the first ultrasonic probe 32 can be improved, thereby being beneficial to further improving the positioning accuracy of the acoustic window and the ultrasonic diagnosis effect.

In the solution provided in this embodiment, the front end of the first ultrasonic probe 32 may also be provided with an infrared imaging sensor. The infrared imaging sensor can be used to detect brain activity of the user and to determine if the coupling pad 41 or the couplant is satisfactory.

In addition, at least one of an accelerometer, a gyroscope, and a magnetic sensor may be further disposed on first stage 22, and may be specifically designed according to the use requirements of transcranial ultrasound application device 100.

In the solution provided in this embodiment, one or more sets of the first mounting assembly 2 and the first detecting assembly 3 may be provided. Optionally, in an embodiment, as shown in fig. 2, to improve the convenience and reliability of using the transcranial ultrasound application device 100, two sets of first mounting assemblies 2 and two sets of first detecting assemblies 3 are disposed on the headstock body 1, and the two sets of first detecting assemblies 3 are cooperatively used to jointly position the skull acoustic window.

The transcranial ultrasound application device 100 provided by the present application is also provided with a control module that can be used to control the position and movement of the first mounting frame 21 and the first stage 22, as well as to control the operation of the first detection assembly 3, but is not limited thereto.

It will be appreciated that the angle and length adjustment of the first mounting bracket 21 may be automatically adjusted by means of a control module or may also be manually adjusted.

The control module may be disposed on the annular rail 12, and the specific manner and location of the control module may be designed according to practical situations, which is not limited herein.

In the solution provided in this embodiment, as shown in fig. 5, the head frame body 1 further includes a connecting rod 13, the connecting rod 13 is erected on the annular guide rail 12, and two ends of the connecting rod 13 are fixedly connected to the annular guide rail 12. The transcranial ultrasound application device 100 further comprises a second mounting assembly 5 and a second detection assembly 6, the second mounting assembly 5 comprises a second mounting frame 51 and a second objective table 52, the second mounting frame 51 is arranged on the connecting rod 13 and is used for mounting the second objective table 52, and the second detection assembly 6 is arranged on the second objective table 52 and is used for conducting ultrasonic stimulation on a target area of the cerebral cortex on the head of a user and acquiring brain electrical signals.

Specifically, the connecting rod 13 is an arc-shaped rod, and when the transcranial ultrasound application device 100 is in use, the connecting rod 13 and the second detection assembly 6 are mounted on the top of the head of the user, and the second detection assembly 6 faces the head of the user.

The second mounting assembly 5 and the second detection assembly 6 may be mounted above or below the connecting rod 13, which is not limited only herein.

In the aspect of ultrasonic application, ultrasonic nerve regulation (Ultrasound Neuromodulation) has been proved to have remarkable treatment effects on diseases such as epilepsy, depression, parkinsonism, drug addiction, sleep dysfunction and the like, but the accurate positioning of a stimulation area is difficult due to the influence of skull. In this scheme, through erect connecting rod 13 structure on annular guide rail 12 to set up second detection component 6 on connecting rod 13, can fix a position the target stimulation region of cerebral cortex on the user's head, and acquire the brain electrical signal, carry out ultrasonic diagnosis etc. has promoted the practicality of transcranial ultrasonic application device 100, has still solved the problem that the target stimulation region of cerebral cortex is inaccurate in the relevant product location, ultrasonic diagnosis difficulty.

Furthermore, the connecting rod 13 also serves to increase the strength of the headstock body 1 to further reduce the risk of deformation of the circular guide 12.

The first detecting unit 3 and the second detecting unit 6 are independent of each other, and can be used simultaneously or individually.

In the solution provided in this embodiment, the second mounting frame 51 includes a fixing seat 511 and a third bracket 512, the fixing seat 511 is disposed on the connecting rod 13, the third bracket 512 is mounted on the fixing seat 511, and the third bracket 512 is a telescopic rod and has an adjustable length.

Depending on the structure of the fixing base 511, the fixing base 511 may be clamped on the connecting rod 13, or may be mounted on the connecting rod 13 by a fastening member such as a bolt, or may be clamped on the connecting rod 13 by a fastening structure such as a buckle, which is specifically designed according to the actual situation, and is not limited only herein.

The third bracket 512 is rotatably disposed on the fixing base 511 through a structure such as a rotating shaft. In use, the positional relationship of the second detection assembly 6 and the user's head can be adjusted by adjusting the angle and length of the third bracket 512.

By adopting the design, the second installation component 5 has reasonable structure and high flexibility.

It will be appreciated that the angle and length adjustment of the second mount 51 may be automatically adjusted by means of a control module or may also be manually adjusted.

In other embodiments, as shown in fig. 6, the second mounting frame 51 may further include a plurality of third brackets 512 connected in a hinged manner, and the specific structure of the second mounting frame 51 may be adjusted according to actual requirements.

In the solution provided in this embodiment, the second detection assembly 6 comprises an electrode pad and a second ultrasound probe.

The electrode slice is attached to the head of the user and used for acquiring the brain electrical signals of the head of the user.

The second ultrasonic probe is used for transmitting ultrasonic waves to the head of the user for ultrasonic stimulation or acquiring ultrasonic brain images. The second ultrasonic probe is a single-vibration element probe or a multi-vibration element probe, the frequency of ultrasonic waves emitted by the second ultrasonic probe is 0.5MHz-20MHz, and the intensity is 1mW/cm ²-3W/cm². For example, the second ultrasound probe may be selected from Olinbas, type A303S-SU Shan Zhenyuan.

The number and shape of the connecting rods 13, and the number and arrangement positions of the second detecting assemblies 6 may be designed according to practical situations, and are not limited only herein.

Furthermore, in some embodiments, at least one of a pressure sensor, a coupling pad, an accelerometer, a gyroscope, a magnetic sensor, an infrared sensor is also disposed on the second stage 52.

In the solution provided in this embodiment, as shown in fig. 2 and 3, the fixing assembly 11 includes an annular head band 111 and a plurality of support rods 112, the plurality of support rods 112 are disposed at intervals along the circumferential direction of the annular head band 111, and one end of each support rod 112 is connected to the annular head band 111, and the other end is connected to the annular rail 12, and the annular head band 111 is used to be worn on the head of a user and used to support the annular rail 12.

Specifically, the annular headband 111 is fastened to the forehead of the user, and the annular rail 12 is installed at a position spaced from the head of the user by the support bar 112.

By adopting the design, the fixing component 11 has reasonable structure, good fixing and supporting effects and easy wearing.

In the solution provided in this embodiment, the annular head band 111 and the support rod 112 are made of a rigid material that is not deformable in order to ensure the supporting effect. Alternatively, in an embodiment, the annular head band 111 and the support rod 112 are both made of plastic, and the annular head band 111 and the support rod 112 are integrally injection molded through an injection molding process.

In the solution provided in this embodiment, the annular head band 111 has an open structure and has a first end and a second end, where the first end is configured with a first adjusting hole, the second end is configured with a second adjusting hole, the first adjusting hole and the second adjusting hole are disposed opposite to each other, and the first adjusting hole and the second adjusting hole are both configured with a rack structure. The fixing assembly 11 further comprises an adjusting knob 113, the adjusting knob 113 is inserted into the first adjusting hole and the second adjusting hole, the adjusting knob 113 is meshed with the rack structure, and the first end and the second end can be driven to move relatively by rotating the adjusting knob 113.

Specifically, the upper wall of the first adjustment hole has a rack structure, and the lower wall of the second adjustment hole has a rack structure. The adjusting knob 113 comprises a connecting portion and a rotating portion which are connected, the connecting portion is also provided with a rack structure, the connecting portion stretches into the first adjusting hole and the second adjusting hole, the rack structure on the connecting portion is meshed with the rack structure in the first adjusting hole and the rack structure in the second adjusting hole, the rotating portion is arranged outside the first adjusting hole and the second adjusting hole, the rotating portion is twisted, the first end and the second end can be driven to move towards different directions, and accordingly tightness adjustment of the annular head band 111 is achieved.

With the above design, by designing the annular head band 111 to be of a tightness-adjustable structure, the applicability of the annular head band 111 can be improved, and the fixing effect thereof can be improved; and the tightness adjustment structure is simple, the adjustment is convenient, and the wearing difficulty of the fixed headstock is reduced.

It should be understood that the structure of the annular head band 111 is not unique, and in some embodiments, a supporting tightness adjusting structure may be further provided on the annular head band 111, or a plurality of adjustable fastening structures may be provided on the annular head band 111, which may be specifically designed according to practical situations, and is not limited herein.

In the solution provided in this embodiment, to avoid interference between the first mounting frame 21 and the fixing component 11, the first mounting frame 21 is connected to an outer sidewall of the annular rail 12, and the supporting rod 112 is connected to an inner sidewall of the annular rail 12.

In the solution provided in this embodiment, a plurality of clamping grooves are provided on the inner side wall of the annular guide rail 12, one end of the supporting rod 112 is fixedly connected with the annular head hoop 111, the other end is clamped in the clamping grooves, the number of the clamping grooves is greater than that of the supporting rod 112, and the installation position of the supporting rod 112 is adjustable.

The tightness of the annular head band 111 is adjustable, and the alignment of the support rod 112 with the annular rail 12 is changed at different tightness, i.e., different sizes. By arranging the plurality of clamping grooves on the annular guide rail 12, the support rod 112 is provided with a plurality of mounting positions on the annular guide rail 12, which is beneficial to improving the alignment and connection effects of the support rod 112 and the annular guide rail 12 and reducing the deformation risk of the annular guide rail 12.

Further, the end of the support rod 112 connected to the annular guide rail 12 may be designed as a snap structure that mates with a clamping groove, or an interference insertion structure, which may be specifically designed according to practical situations, and is not limited herein.

It will be appreciated that in some embodiments, the support rod 112 may be connected to the bottom wall of the annular rail 12 without interference between the first mounting frame 21 and the support rod 112, as is desirable in the design of the annular rail 12; and, the support frame can also be designed into a telescopic rod structure, and can be specifically designed according to actual conditions, and the design is not limited herein.

In the solution provided in the present embodiment, the cross-sectional shape of the annular rail 12 may be T-shaped or L-shaped, but is not limited thereto.

In the solution provided in the present embodiment, the annular guide rail 12 may be made of aluminum alloy, stainless steel or titanium alloy, but is not limited thereto.

In summary, according to the transcranial ultrasound application apparatus 100 provided by the present application, by providing a circular guide rail 12 capable of being mounted on the head of a user, and arranging the first detection component 3 on the circular guide rail 12, the positioning difficulty of the skull acoustic window in brain ultrasound surgery can be reduced, and the positioning accuracy of the skull acoustic window can be improved; and, through setting up connecting rod 13 on annular guide rail 12 to set up second detection component 6 on connecting rod 13, can reduce the location degree of difficulty of target stimulation region and improve the location precision of target stimulation region in the regulation and control of ultrasonic nerve, thereby effectively promoted the use convenience of transcranial ultrasonic application device 100 and the accuracy of ultrasonic diagnosis result.

Embodiment two:

as shown in fig. 10 and 11, the transcranial ultrasound application device 100 provided by the present embodiment includes a headgear body 1, a first mounting assembly 2, and a first detection assembly 3. The headgear body 1 includes a securing assembly 11 and a circular rail 12, the securing assembly 11 being connected to the circular rail 12 and adapted to mount the circular rail 12 to a user's head. The first mounting assembly 2 includes a first mounting frame 21 and a first stage 22, the first mounting frame 21 is slidably connected to the annular rail 12 and is configured to mount the first stage 22, and the first mounting frame 21 is capable of sliding along the annular rail 12 to drive the first stage 22 to rotate circumferentially around the user's head. As shown in fig. 2, 6 and 7, the first detection assembly 3 includes a depth camera 31 and a first ultrasound probe 32 provided on the first stage 22, the depth camera 31 being used to scan the outer contour of the user's head and determine the skull sound window position.

In the solution provided in this embodiment, as shown in fig. 12, the head frame body 1 further includes a connecting rod 13, the connecting rod 13 is erected on the annular guide rail 12, and two ends of the connecting rod 13 are fixedly connected to the annular guide rail 12. The transcranial ultrasound application device 100 further comprises a second mounting assembly 5 and a second detection assembly 6, the second mounting assembly 5 comprises a second mounting frame 51 and a second objective table 52, the second mounting frame 51 is arranged on the connecting rod 13 and is used for mounting the second objective table 52, and the second detection assembly 6 is arranged on the second objective table 52 and is used for acquiring brain electrical signals and performing ultrasonic stimulation on a target area of a cerebral cortex on the head of a user.

In the solution provided in this embodiment, as shown in fig. 10 and 12, the fixing assembly 11 includes a fixing bracket 114, and the fixing bracket 114 is connected to an arbitrary position of the connecting rod 13 and is used for suspending the connecting rod 13 and the circular guide rail 12.

The fixation bracket 114 includes a fixation structure that can be fixedly positioned on a bed frame, a table, a chair, a wall, or the like to achieve a fixation of the position of the transcranial ultrasound application device 100.

The scheme provided by the embodiment enables the fixing head frame to be fixed in external facilities by improving the structure of the fixing assembly 11, and can also effectively improve the use convenience of the fixing head frame.

Embodiment III:

the application provides a using method of a transcranial ultrasonic application device.

The specific structure of the transcranial ultrasound application device 100 is described in the first and second embodiments, and will not be described in detail herein. The using method comprises the following steps:

s1, wearing the transcranial ultrasound application device 100 on the head of a user.

When the diagnosis device is worn, the annular guide rail 12 of the head frame body 1 is erected on the head of a user.

S2, the first detection component 3 is utilized to scan the outer contour of the head of the user and determine the position of the skull sound window.

During the detection, the first detection assembly 3 should be aligned with the user's head to ensure the positioning accuracy of the skull sound window.

S3, adjusting the first mounting frame 21 to enable the first ultrasonic probe 32 to be attached to the head of the user and opposite to the preset skull sound window.

The first mount 21 is adjusted so that the first ultrasonic probe 32 is closely adhered to the skin of the user and the contact pressure is not excessively high to ensure that the ultrasonic diagnosis can be performed normally.

And S4, controlling the first ultrasonic probe 32 to emit ultrasonic signals so as to perform ultrasonic diagnosis.

The first ultrasonic probe 32 can emit ultrasonic waves to the skull sound window for ultrasonic stimulation or ultrasonic brain image acquisition, and by improving the emission intensity of the first ultrasonic probe 32, the requirements of different ultrasonic stimulation or ultrasonic imaging can be met.

In some embodiments, the pressure sensor 33 and the motor 42 are disposed on the transcranial ultrasound application device 100, and in brain ultrasound surgery, the position of the first ultrasound probe 32 can be adjusted according to the real-time monitoring result of the structures such as the pressure sensor 33, so that the first ultrasound probe 32 is configured to be at an optimal incident angle or scanning plane, and high-precision three-dimensional ultrasound imaging is achieved.

The above embodiments are only for illustrating the technical solution of the present application, and not for limiting the same; although the application has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present application, and are intended to be included in the scope of the present application.

Claims

1. A transcranial ultrasound application device, comprising:

2. The transcranial ultrasound application device of claim 1, wherein the first mount comprises a first bracket and a second bracket rotatably coupled, an included angle between the first bracket and the second bracket being adjustable, the first bracket coupled to the annular rail, and the second bracket coupled to the first stage.

3. The transcranial ultrasound application device of claim 2, wherein the second stent is a telescoping rod and is adjustable in length.

4. The transcranial ultrasound application device of claim 1, wherein the first ultrasound probe is a single-element probe or a multi-element probe, and the frequency of the ultrasound waves emitted by the first ultrasound probe is 0.5MHz-20MHz, and the intensity is 1mW/cm ²-3W/cm².

5. The transcranial ultrasound application device of claim 1, wherein the first detection assembly further comprises a pressure sensor disposed on the first stage for detecting a contact pressure between the first ultrasound probe and a user's head.

6. The transcranial ultrasound application device of claim 1, wherein a front end of the first ultrasound probe is provided with a coupling pad through which ultrasound waves emitted by the first ultrasound probe can penetrate.

7. The transcranial ultrasound application device of any one of claims 1-6, wherein the headgear body further comprises a connecting rod that is strung on the annular rail, and both ends of the connecting rod are fixedly connected to the annular rail;

the transcranial ultrasonic application device further comprises a second installation component and a second detection component, the second installation component comprises a second installation frame and a second objective table, the second installation frame is arranged on the connecting rod and used for installing the second objective table, and the second detection component is arranged on the second objective table and used for conducting ultrasonic stimulation on a target area of the cerebral cortex on the head of a user and acquiring brain electrical signals.

8. The transcranial ultrasound application device of claim 7, wherein the second mounting bracket includes a fixed seat and a third bracket, the fixed seat is disposed on the connecting rod, the third bracket is mounted on the fixed seat, and the third bracket is a telescopic rod and has an adjustable length.

9. The transcranial ultrasound application device of claim 7, wherein the second detection assembly comprises an electrode pad and a second ultrasound probe.

10. The transcranial ultrasound application device of claim 7, wherein the fixation assembly comprises a fixation bracket connected to any location of the connecting rod and for suspending the connecting rod and the annular rail.

11. The transcranial ultrasound application device of any one of claims 1-6, wherein the fixation assembly comprises an annular headband and a plurality of support rods spaced circumferentially about the annular headband, and wherein one end of the support rods is connected to the annular headband and the other end is connected to the annular rail, the annular headband being for wearing on a user's head and for supporting the annular rail.

12. The transcranial ultrasound application device of claim 11, wherein the annular headband is an open structure and has a first end with a first adjustment aperture disposed thereon and a second end with a second adjustment aperture disposed thereon, the first and second adjustment apertures being disposed opposite one another, and wherein the first and second adjustment apertures are each configured with a rack structure;

13. The transcranial ultrasound application device according to claim 11, wherein a plurality of clamping grooves are formed in the inner side wall of the annular guide rail, one end of the supporting rod is fixedly connected with the annular head hoop, the other end of the supporting rod is clamped in the clamping grooves, the number of the clamping grooves is larger than that of the supporting rod, and the installation position of the supporting rod is adjustable.