CN116669687A - antimicrobial composition - Google Patents

Abstract

The present invention relates to an antimicrobial composition, a process for its preparation and its use. The antimicrobial composition comprises at least one silver compound, at least one amino acid, at least one fatty acid and water, describes the use of the antimicrobial composition in personal care and home care compositions.

Description

Antimicrobial compositions

Field of the Invention

The present invention relates to an antimicrobial composition comprising a silver compound. More particularly, the present invention relates to an antimicrobial composition comprising a silver compound, which antimicrobial composition can be used in a personal care or home care composition.

Background of the Invention

Microorganisms and infection risks are a major concern worldwide. According to studies, about 80% of infections begin with surface contact. Bacteria and fungi are everywhere around us and can multiply as long as conditions are favorable. This leads to contamination and the spread of infectious diseases, which is a major public health issue.

Silver has long been considered antimicrobial. For example, silver nitrate was routinely used to wipe newborns to prevent blinding eye infections until the past decade, when it was thought that nitrates would cause other problems. Silver is a broad-range antimicrobial agent that has been shown to be effective against most harmful microorganisms present in daily life, such as Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Propionibacterium acnes, Aspergillus, Candida albicans, Malassezia furfur. Silver sulfadiazine is commonly used as an antibiotic burn dressing in the form of a topical cream containing 1% silver sulfadiazine in micronized form. It has antimicrobial activity and is bactericidal against both Gram-negative and Gram-positive bacteria.

US5688981 discloses novel silver chelators and surfactants that exhibit photosensitivity and antimicrobial activity. Silver is chelated with ethylenediaminetriacetic acid (ED3A) or with N-acyl ED3A. Antimicrobial activity is exhibited even at very low silver levels.

EP2986698 discloses soap bars, particularly high pH soap bars, which provide improved biocidal activity against both Gram-positive and Gram-negative bacteria at the relatively short contact times typical of soap bar use.

EP3099773 discloses a cleaning composition comprising a surfactant, an oligodynamic metal, a chelating agent and a polymer having a group comprising a site having one or more lone pairs of electrons. The disclosed composition provides improved killing activity against Gram-positive and Gram-negative bacteria at relatively short contact times.

EP3099772 discloses an aqueous composition comprising a microdynamic metal or ion thereof, a chelating agent and less than 1 wt% of free base.

JP5377003 discloses silver oxide mixed with phytic acid and a chelating agent such as ethylenediaminetetraacetic acid to improve the stability of the formulation and avoid discoloration due to UV radiation.

Phytic acid, also known as inositol polyphosphate, produces phytate anions at physiological pH. Both phytic acid and phytate ions have a strong ability to bind to dietary minerals such as zinc, calcium, and iron, thereby inhibiting their absorption and leading to the formation of precipitates.

There is a continuing need to provide compositions having silver compounds that have good stability and provide high antimicrobial efficacy, are low cost and non-toxic.

Thus, in one aspect of the present invention, there is provided an antimicrobial composition comprising at least one silver compound, at least one amino acid, at least one fatty acid and water.

In another aspect the present invention provides the use of an antimicrobial composition as described herein in a personal care or home care composition, preferably as an antimicrobial agent.

In another aspect the present invention provides a personal care or home care composition comprising the antimicrobial composition described herein.

In yet another aspect the present invention provides a process for preparing the antimicrobial composition described herein, wherein the composition is prepared by mixing at least one silver compound, at least one amino acid, at least one fatty acid and water.

DETAILED DESCRIPTION OF THE INVENTION

Silver, zinc, copper and other metals are widely used in antimicrobial cleaning/cleaning compositions. However, their oxides and some salts, especially those of silver, are sensitive to pH, heat and light. Under these conditions, the active metals often fade to form brown, gray or black particles. The particles tend to settle and/or agglomerate. Further, most silver oxides and salts are poorly soluble in water. Silver-based antimicrobial agents have very high antimicrobial effects. However, their efficacy tends to gradually diminish over time, especially in the alkaline environment of cleaning/cleaning compositions.

It was surprisingly found that combining silver compounds with fatty acids and amino acids prevented discoloration of the composition due to UV radiation and/or pH changes and improved stability. Even after extended storage, there was no agglomeration or precipitation in the composition. The present invention therefore provides stable, non-toxic antimicrobial compositions and processes for preparing antimicrobial compositions that are low in cost and can be scaled up for commercial production.

In the present application, including all embodiments of all aspects of the invention, the following definitions apply unless otherwise specifically stated. Unless otherwise stated, all percentages are by weight (w/w) of the respective component or total composition, respectively. "Weight %" means weight percentage; "volume %" means volume percentage; "mole %" means mole percentage. Unless otherwise stated, all ratios are weight ratios (weight/weight). Preferably, reference to "parts", such as a mixture of 1 part X and 3 parts Y, is a ratio by weight. +/- indicates standard deviation. All ranges are inclusive and combinable. Unless otherwise stated, all measurements should be understood to be made at 23°C and under ambient conditions, where "ambient conditions" means at a pressure of about 1 atmosphere (atm) and at about 50% relative humidity. "Relative humidity" refers to the ratio (expressed as a percentage) of the moisture content in the air to the saturated moisture level at the same temperature and pressure. Relative humidity can be measured with a hygrometer, in particular with a hygrometer from International's probe hygrometer. "Minute (min)" herein means "minute (minute)" or "minutes (minutes)". "Mole (mol)" herein means mole (mole). "Gram (g)" after a number herein means "gram (gram)" or "grams (grams)". "Ex. (Ex.)" means "example (example)". "Qs" and "QS" herein mean quantumsates, therefore, as much as required. In the context of content, this refers to obtaining 100% by weight as the total amount. For example, fill up with water to obtain a total of 100% by weight of all ingredients. In the context of pH, "qs" means using the amount of acid and base required to obtain the desired pH.

As used herein, the term "comprising" is not meant to be limited to any subsequently stated elements, but rather to include unspecified elements of primary or secondary functional importance. In other words, the steps, elements, or selections listed need not be exhaustive. Whenever the words "comprising" or "having" are used, these terms are meant to be equivalent to "comprising" as defined above. Where the compositions of the present invention are described as "comprising" or "including" particular components or materials, narrower embodiments in which the compositions may be "essentially composed of" or "consisting of" the described components or materials may also be contemplated.

"Derivatives" include, but are not limited to, amide, ether, ester, amino, carboxyl, acetyl, acid, salt and/or alcohol derivatives of a given compound. In at least one embodiment, "derivatives thereof" means amide, ether, ester, amino, carboxyl, acetyl, acid, salt and alcohol derivatives.

As used herein, an "antimicrobial agent" is a substance that kills or inhibits the growth of microorganisms such as bacteria, fungi, or viruses.Antimicrobial substances can kill microorganisms (microbicidal) or prevent the growth of microorganisms (microbial static).

As used herein, the term "parts per million (ppm)" or "parts per million" is a measure of the concentration of a solution. 1 ppm is one part by weight or volume of a solute in 1 million parts by weight or volume of a solution.

"Cosmetically acceptable" is to be understood in the broadest sense, describing compositions or components suitable for use in contact with human keratinous tissue without undue toxicity, incompatibility, instability, allergic response, etc. All compositions described herein that have the purpose of being applied directly to keratinous tissue are cosmetically acceptable.

The present invention provides an antimicrobial composition comprising at least one silver compound, at least one amino acid, at least one fatty acid and water.

Silver compounds

Antimicrobial composition of the present invention comprises at least one silver compound.Suitable silver compound that can be used includes but is not limited to silver oxide, silver halide such as silver chloride, silver iodide, silver bromide, silver fluoride, silver citrate, silver acetate, silver nitrate, silver carbonate, silver sulfate, silver sulfide, silver phosphate, silver benzoate, silver salicylate and mixtures thereof.In a preferred embodiment, the silver compound used can be silver oxide.

The silver compound may be present at 0.01 to 0.3 wt %, preferably 0.09 to 0.11 wt %, more preferably 0.095 to 0.105 wt %, and most preferably 0.099 to 0.101 wt %, based on the total weight of the antimicrobial composition.

Amino Acids

Antimicrobial compositions of the present invention comprise at least one amino acid. Any kind of amino acid and their derivatives can be used. Suitable amino acids can be α-, β-, γ- or δ-amino acids with aliphatic, non-cyclic or aromatic side chains, and/or containing hydroxyl or sulfhydryl groups. Suitable amino acid examples include but are not limited to alanine, arginine, asparagine, aspartic acid, lysine, leucine, isoleucine, glycine, glutamic acid, serine, threonine, glutamine, histidine, methionine, proline, tyrosine, cysteine, phenylalanine, tryptophan, valine and mixtures thereof. Other examples are non-protein amino acids such as hydroxyproline, citrulline, ornithine, selenomethionine, selenocysteine and mixtures thereof. Most preferably, the amino acid used is arginine.

Preferably, the amino acid is present at 0.2 to 6 wt%, more preferably 1.0 to 3.0 wt%, and most preferably 1.5 to 2.5 wt%, based on the total weight of the antimicrobial composition.

fatty acid

Antimicrobial composition of the present invention comprises at least one fatty acid.Suitable fatty acid comprises saturated and undersaturated fatty acid, linear or branched type, has C ₆ to C ₂₂ carbon chain length.In a preferred embodiment, fatty acid is the aliphatic acid with C ₆ to C ₂₂ carbon chain length.Fatty acid can be saturated or undersaturated fatty acid.For example, undersaturated fatty acid can be mono-unsaturated, di-unsaturated, tri-unsaturated, tetra-unsaturated, penta-unsaturated or hexa-unsaturated. Examples of suitable fatty acids include, but are not limited to, caproic acid, heptanoic acid, octanoic acid, nonanoic acid, decanoic acid, undecanoic acid, dodecaned acid, tridecaned acid, tetradecaned acid, pentadecanoic acid, hexadecanoic acid, heptadecaned acid, behenic acid, octadecanoic acid, nonadecaned acid, eicosanoic acid, heneicosanoic acid, myristoleic acid, palmitoleic acid, sapienic acid, elaidic acid, vaccenic acid, oleic acid, gadoleic acid, eicosenoic acid, paullinic acid, erucic acid, linoleic acid, eicosadienoic acid, eicosadienoic acid, docosadienoic acid, α- and γ-linolenic acid, pinoleic acid, α- and β-eleostearic acid, meadoleic acid, 5,8,11-trienoic acid, and 13-14-oleic acid. The fatty acid is octanoic acid, dihomo-γ-linolenic acid, eicosa-11,14,17-trienoic acid, linolenic acid, arachidonic acid, eicosatetraenoic acid, adrenic acid, bosseopentaenoic acid, eicosa-5,8,10,12,14-pentaenoic acid, ozubondo acid, eurycoma acid, docosahexaenoic acid, and mixtures thereof. In a preferred embodiment, the fatty acid is octanoic acid.

Preferably, the fatty acid is present at 0.025 to 0.75 wt%, more preferably 0.1 to 0.5 wt%, and most preferably 0.2 to 0.3 wt%, based on the total weight of the antimicrobial composition.

In a preferred embodiment,

The silver compound (particularly preferably silver oxide) is present in an amount of 0.01 to 0.3 wt %, based on the total weight of the antimicrobial composition;

The amino acid (particularly preferably arginine) is present in an amount of 0.2 to 6 wt %, based on the total weight of the antimicrobial composition; and

The fatty acid, particularly preferably caprylic acid, is present at 0.025 to 0.75 weight percent, based on the total weight of the antimicrobial composition.

In a preferred embodiment,

The silver compound (particularly preferably silver oxide) is present in an amount of 0.09 to 0.11 wt %, based on the total weight of the antimicrobial composition;

The amino acid (particularly preferably arginine) is present in an amount of 1.0 to 3.0 wt %, based on the total weight of the antimicrobial composition; and

The fatty acid, particularly preferably caprylic acid, is present at 0.1 to 0.5 wt %, based on the total weight of the antimicrobial composition.

In a preferred embodiment,

The silver compound (particularly preferably silver oxide) is present in an amount of 0.095 to 0.105 wt %, based on the total weight of the antimicrobial composition;

The amino acid (particularly preferably arginine) is present in an amount of 1.5 to 2.5 wt %, based on the total weight of the antimicrobial composition; and

The fatty acid, particularly preferably caprylic acid, is present at 0.2 to 0.3 wt %, based on the total weight of the antimicrobial composition.

In a particularly preferred embodiment, the antimicrobial composition of the present invention comprises

0.01 to 0.3 weight percent silver oxide, based on the total weight of the antimicrobial composition;

0.2 to 6 weight percent arginine, based on the total weight of the antimicrobial composition; and

0.025 to 0.75 weight percent of caprylic acid, based on the total weight of the antimicrobial composition.

water

The antimicrobial composition of the present invention comprises water. Water is useful for economic and ecological reasons. As used herein, water can be softened water, deionized water, distilled water, mineral water or tap water, preferably softened water.

In at least one preferred embodiment, the antimicrobial composition of the present invention comprises 10 to 99.9 wt. %, or 10 to 98.5 wt. %, or 10 to 98 wt. %, or 10 to 97.8 wt. %, or 10 to 97.5 wt. %, or 10 to 97 wt. %, or 10 to 95 wt. %, or 20 to 94 wt. %, or 30 to 93 wt. %, or 40 to 92 wt. %, or 50 to 91 wt. %, or 60 to 90 wt. %, or 70 to 90 wt. % of water, based on the total weight of the antimicrobial composition.

The antimicrobial composition of the present invention may include additional solvents. Advantageously, the solvent is cosmetically acceptable. Optionally, the composition includes a water-miscible or water-soluble solvent such as a lower alkyl alcohol. In at least one embodiment, the composition includes a C1-C5 alkyl monoalcohol, preferably a C2-C3 alkyl monoalcohol. The alcohol that may be present is particularly a lower monohydric or polyhydric alcohol having 1 to 4 carbon atoms, such as preferably ethanol or isopropanol.

Optionally, the composition comprises a water-soluble polyol. In at least one embodiment, the water-soluble polyol is a polyol having two or more hydroxyl groups in the molecule. In at least one embodiment, the water-soluble polyol is selected from the following group: diols such as ethylene glycol, propylene glycol, trimethylene glycol, 1,2-butanediol, 1,3-butanediol, 1,4-butanediol, butylene glycol, 2,3-butanediol, pentanediol, 2-butene-1,4-diol, hexanediol, octanediol; triols such as glycerol, trimethylolpropane, 1,2,6-hexanetriol, etc.; tetraols such as pentaerythritol; pentaols such as Such as xylitol (xylytol) and the like; hexahydric alcohols such as sorbitol and mannitol; polyol polymers such as diethylene glycol, dipropylene glycol, polyethylene glycol, polypropylene glycol, tetraethylene glycol, dipropylene glycol, polyethylene glycol, tripropylene glycol, tetrapropylene glycol, polypropylene glycol; glycol alkyl ethers such as ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, ethylene glycol monophenyl ether, ethylene glycol monohexyl ether, ethylene glycol mono-2-methylhexyl ether, ethylene glycol isopentyl ether, ethylene glycol benzyl ether, Ethylene glycol isopropyl ether, ethylene glycol dimethyl ether, ethylene glycol diethyl ether, ethylene glycol dibutyl ether; glycol alkyl ethers such as diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol monobutyl ether, diethylene glycol dimethyl ether, diethylene glycol diethyl ether, diethylene glycol butyl ether, diethylene glycol methyl ethyl ether, triethylene glycol monomethyl ether, triethylene glycol monoethyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene glycol monobutyl ether, propylene glycol isopropyl ether, dipropylene glycol methyl ether, dipropylene glycol ethyl ether, dipropylene glycol butyl ether; polyol ether esters such as ethylene glycol monomethyl ether acetate, ethylene glycol monoethyl ether acetate, ethylene glycol monobutyl ether acetate, ethylene glycol monophenyl ether acetate, ethylene glycol hydrogen adipate, ethylene glycol hydrogen succinate, diethylene glycol monoethyl ether acetate, diethylene glycol monobutyl ether acetate, propylene glycol monomethyl ether acetate, propylene glycol monoethyl ether acetate, propylene glycol monopropyl ether acetate, propylene glycol monophenyl ether acetate; glycerol monoalkyl ethers such as xyl alcohol alcohol), squalane alcohol, batyl alcohol; sugar alcohols such as sorbitol, maltitol, maltotriose, mannitol, sucrose, erythritol, glucose, fructose, starch sugar, maltose, xylytose, starch sugar reducing alcohol, glysolid, tetrahydrofurfuryl alcohol, POE tetrahydrofurfuryl alcohol, POP butyl ether, POP POE butyl ether, tripolyoxypropylene glycerol ether, POP glycerol ether, POP glycerol ether phosphoric acid, POP POE pentaerythritol ether and mixtures thereof. Natural solvents can also be used. In at least one embodiment, the composition comprises a solvent selected from the following groups: vegetable oil, honey, plant-derived sugar compositions and mixtures thereof.

In a preferred embodiment, the antimicrobial composition is stable to light and heat for one month, preferably three months, more preferably six months under accelerated stability conditions. In a preferred embodiment, the antimicrobial composition is stable to light and heat for at least one month, preferably at least three months, more preferably at least six months under accelerated stability conditions. Unless otherwise indicated, the term accelerated stability conditions refers to 40 ± 2 ℃ and 75 ± 5% humidity. The antimicrobial composition of the present invention can be prepared by methods known in the art. In a preferred embodiment, the antimicrobial composition is prepared by a process of the present invention.

The present invention provides a process for preparing an antimicrobial composition as described herein, wherein the composition is prepared by mixing at least one silver compound, at least one amino acid, at least one fatty acid and water.

In a preferred embodiment, the antimicrobial composition of the present invention is prepared by a process comprising the following steps:

a. mixing water and at least one amino acid at room temperature and heating the reaction mixture;

b. adding at least one amino acid to the reaction mixture and maintaining for at least 2 hours;

c. adding water to the reaction mixture;

d. Add at least one fatty acid and maintain the reaction mixture under stirring for 1-2 hours.

e. filtering the reaction mixture to obtain an antimicrobial composition;

f. Optionally, add water to the antimicrobial composition to adjust the silver concentration at the desired level.

"Reaction blend" is understood to be a mixture of the starting materials and optionally any solvent or other materials used or useful in the reaction.

In at least one embodiment, the heating in step (a) occurs by heating the reaction blend to at least 35°C, more preferably at least 40°C, even more preferably at least 45°C, most preferably 40°C to 50°C.

In at least one embodiment, the maintaining in step (b) occurs for at least 3 hours, more preferably at least 4-6 hours, and most preferably at least 4 hours.

In at least one embodiment step (c) occurs at at least 25°C, more preferably at least 30°C, even more preferably at least 35°C, most preferably at 30°C to 35°C.

In at least one embodiment, the filtration in step (e) occurs at room temperature using a hyflowbed.

Preferably, the antimicrobial composition of the present invention is incorporated into a personal care composition or a home care composition. In a preferred embodiment, the antimicrobial composition of the present invention is incorporated into a personal care composition. In another preferred embodiment, the antimicrobial composition of the present invention is incorporated into a home care composition.

In a preferred embodiment, the antimicrobial composition of the present invention is incorporated into a personal care composition or a home care composition to provide an antimicrobial effect.

Preferably, the antimicrobial composition of the present invention is used as an antimicrobial agent.

The present invention provides the use of an antimicrobial composition as described herein in a personal care or home care composition, preferably as an antimicrobial agent. Preferably, the present invention provides the use of an antimicrobial composition as described herein in a personal care or home care composition as an antimicrobial agent. In a preferred embodiment, the present invention provides the use of an antimicrobial composition as described herein in a personal care composition. In another preferred embodiment, the present invention provides the use of an antimicrobial composition as described herein in a home care composition. In a preferred embodiment, the present invention provides the use of an antimicrobial composition as described herein in a personal care composition as an antimicrobial agent. In another preferred embodiment, the present invention provides the use of an antimicrobial composition as described herein in a home care composition as an antimicrobial agent.

The present invention provides personal care or home care compositions comprising an antimicrobial composition as described herein. In a preferred embodiment, the present invention provides a personal care composition comprising an antimicrobial composition as described herein. In another preferred embodiment, the present invention provides a home care composition comprising an antimicrobial composition as described herein.

Preferably, the personal care composition is selected from the following group: shampoo, hair and/or skin conditioner, shower gel, hand soap, facial cleanser, facial mask, foam bath, intimate wash, bath oil, cleansing milk, micellar water, makeup remover, cleansing wipes, hair mask, perfume, liquid soap, shaving soap, shaving foam, cleansing foam, day cream, anti-aging cream, body milk, body lotion, body mousse, facial serum, eye cream, sunscreen lotion, sunscreen, face cream, after shave lotion, pre-shave cream, hair removal cream, skin whitening gel, self-tanning cream, acne gel, mascara, foundation, makeup Primer, concealer, blush, blush bronzer, blemish corrector (bb) cream, eyeliner, night cream, eyebrow gel, highlighter, lip gloss, hand sanitizer, hair oil, nail polish remover, hairspray, hair styling cream, anti-frizz hair serum, scalp treatment, hair dye, hair tail repair nourishing gel, deodorant, antiperspirant, baby cream, insect repellent, hand cream, sunscreen gel, foot cream, scrub, body scrub, cellulite treatment, bar soap, cuticle lubricant, lip balm, hair treatment, eyeshadow, bath additive, moisturizing body spray, eau de toilette, lubricating gel, moisturizer, serum, toner, body lotion (aqua sorbet), milk gel, styling mousse, dry shampoo, lipstick, lip gloss, body oil, shower gel, skin lightener, lip pencil, hair spray, conditioner, sunscreen cream, ointment and lipstick.

In a preferred embodiment, the personal care composition is a hand wash, body wash, deodorant, or antiperspirant.

In at least one preferred embodiment, the personal care composition is for use on the skin.

In at least one preferred embodiment, the personal care composition is for use on the body.

In at least one preferred embodiment, the personal care composition is for use on the hands.

In particular embodiments, the personal care composition is a body wash.

In particular embodiments, the personal care composition is a hand wash.

In particular embodiments, the personal care composition is a deodorant or an antiperspirant.

In at least one preferred embodiment, the composition is an emulsion or a gel, preferably an oil-in-water (o/w) emulsion, a cream gel or a hydrogel.

Preferably, the home care composition is selected from the group consisting of laundry detergents, fabric softeners, multi-purpose cleaners, household cleaners, hard surface cleaners such as floor cleaners, toilet cleaners, bathroom cleaners, kitchen cleaners. Also preferably, the home care composition may be a hand dishwashing composition. In a preferred embodiment, the home care composition is a laundry detergent, a fabric softener or a multi-purpose cleaner.

In at least one preferred embodiment, the home care composition is used on fabrics.

In at least one preferred embodiment, the home care composition is used on hard surfaces.

In a particular embodiment, the home care composition is a laundry detergent. The laundry detergent may be, for example, in liquid form or in powder form.

In a particular embodiment, the home care composition is a fabric softener.

In a particular embodiment, the home care composition is a multi-purpose cleaner.

In a particular embodiment, the home care composition is a hard surface cleaner.

All-purpose cleaners or hard surface cleaners can, for example, be used to clean earthenware surfaces, stone surfaces, ceramic surfaces, glass surfaces, stainless steel surfaces, metal surfaces, plastic surfaces, linoleum surfaces, wood surfaces.

In a preferred embodiment, the all-purpose cleaner or hard surface cleaner can be used to:

- achieve a cleaning effect on a surface that has been treated with a cleaning agent, or

- render the surface to which the cleaning agent has been applied hydrophilic, or

- produces a shine on surfaces where the cleaning agent has been used, or

- Improve the drying speed of surfaces after cleaning, or

- to obtain permanent properties, preferably "anti-stain", "anti-mark" or "anti-streaking" properties, on the surface to which the cleaning agent has been applied, or

- reduce re-contamination of surfaces where cleaning agents have been used, or

- helps to repeat the cleaning of surfaces after the cleaning agent has been used, or

- To achieve a repair effect on surfaces that have been treated with cleaning agents, or

- remove greasy residues or lime soap residues from surfaces where cleaning agents have been used, or

- remove dirt from surfaces on which the cleaning agent has been applied or reduce newly deposited dirt on surfaces on which the cleaning agent has been applied, or

- minimize or prevent the formation of biofilm on surfaces where the cleaning agent has been used, or

-Easy to clean surfaces after using detergent.

In one embodiment, the all-purpose cleaner or hard surface cleaner remains on the surface after application (a "leave-on" application).

In another embodiment, the all-purpose cleaner or hard surface cleaner is removed from the surface after application and preferably rinsed with water (a "rinse-off" application).

Typically, the personal care or home care composition comprises 0.0001 to 10 wt. %, preferably 0.0005 to 10 wt. %, more preferably 0.001 to 10 wt. %, particularly preferably 0.01 to 5 wt. % of the antimicrobial composition, based on the total weight of the personal care or home care composition.

Typically, the amount of at least one silver compound in the personal care or home care composition of the present invention is from greater than 0 to 10%, preferably 0.0001% to 10% by weight, more preferably 0.0005% to 5% by weight, and particularly preferably 0.0005% to 1% by weight, based on the total weight of the personal care or home care composition of the present invention. Preferably, at least one silver compound is present in the personal care or home care composition of the present invention at 1 ppm to 10000 ppm, more preferably 5 ppm to 1000 ppm, and most preferably 5 ppm to 100 ppm.

The personal care or home care composition of the present invention may comprise one or more additional components, the amount of which may be at least 0.01 wt %, preferably at least 0.05 wt %, more preferably at least 0.1 wt %, even more preferably at least 0.5 wt %, particularly preferably at least 1 wt % of the personal care or home care composition.

Preferably, the additional components are selected from the following groups: acidity regulators, colorants, regulators, emulsifiers, film formers, fragrances, glossing agents, humectants, lubricants, moisturizers, pigments, preservatives, skin penetration enhancers, stabilizers, surfactants, thickeners and viscosity regulators. More preferably, the additional components are selected from the following groups: acidity regulators, glossing agents, lubricants and surfactants.

Suitable lubricants are, for example, fatty alcohol components having 6 to 8 carbon atoms. Surfactants may, for example, be selected from non-polymeric cationic quaternary ammonium compounds, in particular cetyltrimethylammonium chloride (CTAC).

The personal care or home care composition of the present invention may optionally contain anionic surfactants, for example, alkylbenzene sulfonates, alkyl sulfates, alkyl ether sulfates, alkyl sulfonates, alkyl ether carboxylates, sulfosuccinates, isethionates, taurates, glycinates, and/or acylglutamates. The alkyl chains of the mentioned surfactants may be of synthetic or natural origin and consist of 8 to 30, preferably 8 to 18 and more preferably 12 to 14 carbon atoms arranged in a linear or branched manner. In one embodiment, the anionic surfactant is selected from alkylbenzene sulfonates and alkyl ether sulfates. Preferred alkylbenzene sulfonates are linear alkylbenzene sulfonates having an alkyl chain length of _C8 - _C15 , preferably _C12 - _C14 .

Anionic surfactants for use according to the invention are preferably fatty sulfates such as fatty alcohol sulfates, fatty alcohol ether sulfates, dialkyl ether sulfates, monoglyceride sulfates, and fatty sulfonates such as alkylsulfonates, olefinsulfonates, ethersulfonates, n-alkylethersulfonates, estersulfonates and ligninsulfonates. Also useful in the context of the present invention are alkylbenzenesulfonates, fatty acid cyanamides, sulfosuccinates (sulfosuccinates), sulfosuccinamates, sulfosuccinamides, fatty acid isethionates, amidoalkylsulfonates (fatty acid taurine), fatty acid sarcosinates, ethercarboxylates and alkyl (ether) phosphates, and also alkyl ethers of α-sulfofatty acid salts, acylglutamates, monoglyceride hydrogensulfates and glycerol hydrogensulfate.

Among them, fatty alcohol sulfates and/or fatty alcohol ether sulfates, in particular fatty alcohol sulfates, are preferred. Fatty alcohol sulfates are the products of the sulfation reaction of the corresponding alcohols, while fatty alcohol ether sulfates are the products of the sulfation reaction of alkoxylated alcohols. Those skilled in the art generally understand that alkoxylated alcohols mean the reaction products of alkylene oxides, preferably ethylene oxide, and alcohols (preferably with long-chain alcohols in the context of the present invention). Typically, depending on the reaction conditions, n moles of ethylene oxide and 1 mole of alcohol produce a complex mixture of addition products with different degrees of ethoxylation. A further embodiment of the alkoxylation involves the use of an alkylene oxide mixture, preferably a mixture of ethylene oxide and propylene oxide. Preferred fatty alcohol ether sulfates are sulfates of fatty alcohols having 1 to 4 ethylene oxide units (EO), in particular 1 to 2 EO, for example a low ethoxylation level of 1.3EO.

Anionic surfactants are typically used in salt form, but are also used in acid form. Preferred salts are alkali metal salts, alkaline earth metal salts, ammonium salts and mono-, di- or trialkanol ammonium salts, such as mono-, di- or triethanolammonium salts, in particular lithium, sodium, potassium or ammonium salts, more preferably sodium or potassium salts, particularly preferably sodium salts.

In at least one embodiment, the anionic surfactant is an acyl glycinate surfactant. Preferably, the acyl glycinate surfactant conforms to formula (Y):

in

R ^1a is a linear or branched saturated alkyl group having 6 to 30, preferably 8 to 22, particularly preferably 8 to 18 carbon atoms or a linear or branched mono- or polyunsaturated alkenyl group having 6 to 30, preferably 8 to 22, and particularly preferably 12 to 18 carbon atoms, and Q _a ⁺ is a cation. In at least one preferred embodiment, Q _a ⁺ is selected from the following group: Li ⁺ , Na ⁺ , K ⁺ , Mg ⁺⁺ , Ca ⁺⁺ , Al ⁺⁺⁺ , NH ₄ ⁺ , monoalkylammonium ions, dialkylammonium ions, trialkylammonium ions and tetraalkylammonium ions or combinations thereof. Optionally, R ^1a is a (C ₁ -C ₂₂ )-alkyl group or a (C ₂ -C ₁₀ )-hydroxyalkyl group. In at least one preferred embodiment, the acyl glycinate surfactant is selected from sodium cocoyl glycinate and potassium cocoyl glycinate. In at least one preferred embodiment, the acyl glycinate surfactant is selected from those that conform to formula (Y), wherein R ^1a is C ₁₁ -alkyl, C ₁₂ -alkyl, C ₁₃ -alkyl or C ₁₄ -alkyl, particularly preferably C ₁₁ -alkyl or C ₁₃ -alkyl. In at least one preferred embodiment, the acyl glycinate surfactant is selected from those that conform to formula (Y), wherein R ^1a is C ₁₅ -alkyl, C ₁₆ -alkyl, C ₁₇ -alkyl or C ₁₈ -alkyl, particularly preferably C ₁₅ -alkyl or C ₁₇ -alkyl.

In at least one preferred embodiment, the anionic surfactant is a glutamate surfactant. Preferably, the anionic surfactant is a glutamate surfactant conforming to formula (Z) or a salt thereof.

in

R ^' is HOOC-CH ₂ -CH ₂ - or M ⁺ -OOC-CH ₂ -CH ₂ -, wherein M ⁺ is a cation; and wherein R is a linear or branched saturated alkyl group having 6 to 30, preferably 8 to 22, more preferably 8 to 18 carbon atoms, or a linear or branched mono- or polyunsaturated olefin group having 6 to 30, preferably 8 to 22, more preferably 12 to 18 carbon atoms. In at least one preferred embodiment, M ⁺ is a metal cation. In at least one preferred embodiment, M ⁺ is selected from the group consisting of Li ⁺ , Na ⁺ , K ⁺ , Mg ⁺⁺ , Ca ⁺⁺ , Al ⁺⁺⁺ , NH ₄ ⁺ , monoalkylammonium ions, dialkylammonium ions, trialkylammonium ions and tetraalkylammonium ions or combinations thereof. In at least one preferred embodiment, the glutamate surfactant is selected from sodium cocoyl glutamate and potassium cocoyl glutamate. In at least one preferred embodiment, the glutamate surfactant is selected from those that conform to formula (Z), wherein R is C ₁₁ -alkyl, C ₁₂ -alkyl, C ₁₃ -alkyl or C ₁₄ -alkyl, particularly preferably C ₁₁ -alkyl or C ₁₃ -alkyl. In at least one preferred embodiment, the glutamate surfactant is selected from those that conform to formula (Z), wherein R is C ₁₅ -alkyl, C ₁₆ -alkyl, C ₁₇ -alkyl or C ₁₈ -alkyl, particularly preferably C ₁₅ -alkyl or C ₁₇ -alkyl. In at least one preferred embodiment, the composition comprises 0.01 wt % to 30 wt %, preferably 1 wt % to 25 wt %, more preferably 5 wt % to 20 wt %, even more preferably 12 wt % to 18 wt % of glutamate surfactant.

The personal care or home care composition may comprise, for example, 0.5 wt% to 45 wt%, preferably 1 wt% to 30 wt%, more preferably 2 wt% to 25 wt%, more preferably 5 wt% to 20 wt%, more preferably 12 wt% to 18 wt% of anionic surfactant.

The additional surfactants may be nonionic, amphoteric and/or cationic surfactants, for example betaines, amidobetaines, amine oxides, amidoamine oxides, fatty alcohol polyglycol ethers, alkyl polyglycosides or quaternary ammonium compounds.

Other nonionic surfactants may be, for example, alkoxylates, such as polyglycol ethers, fatty alcohol polyglycol ethers (fatty alcohol alkoxylates), alkylphenol polyglycol ethers, end-capped polyglycol ethers, mixed ethers and hydroxy mixed ethers and fatty acid polyglycol esters. Similarly, ethylene oxide-propylene oxide block copolymers and fatty acid alkanolamides and fatty acid polyglycol ethers may be used. Another important class of nonionic surfactants that can be used according to the invention is polyol surfactants and in particular carbohydrate surfactants, such as alkyl polyglycosides, in particular alkyl polyglucosides.

Suitable fatty alcohol polyglycol ethers are ethylene oxide (EO)- and/or propylene oxide (PO)-alkoxylated unbranched or branched, saturated or unsaturated _C8 - _C22 alcohols having an alkoxylation level of up to 30, preferably ethoxylated _C10 - _C18 fatty alcohols having an ethoxylation level of less than 30, more preferably 1 to 20, particularly preferably 1 to 12 and very preferably 1 to 8, for example _C12 - _C14 fatty alcohol ethoxylates with 8 EO.

Alkyl polyglycosides are surfactants which can be obtained by the relevant processes of preparative organic chemistry by reaction of sugars and alcohols which give mixtures of monoalkylated, oligomeric or polymeric sugars. Preferred alkyl polyglycosides are alkyl polyglucosides, wherein the alcohol is more preferably a long-chain fatty alcohol or a mixture of long-chain fatty alcohols with branched or unbranched _C8- to _C18 -alkyl chains, and the oligomerization level (DP) of the sugar is 1 to 10, preferably 1 to 6, more preferably 1.1 to 3 and particularly preferably 1.1 to 1.7, for example _C8 - _C10 -alkyl-1,5-glycosides (DP is 1.5).

In at least one embodiment, the nonionic surfactant is selected from N-methyl-N-acylglucosamines, preferably N-methyl-N-acylglucosamines of formula (X):

Wherein ^Ra is selected from saturated or unsaturated hydrocarbon chains having 5 to 23 carbon atoms. Preferably, ^Ra in formula (X) is selected from saturated or unsaturated hydrocarbon chains having 7 to 17 carbon atoms. In a preferred embodiment, ^Ra in formula (X) is selected from saturated hydrocarbon chains having 7 to 17 carbon atoms. In a preferred embodiment, ^Ra in formula (X) is selected from unsaturated hydrocarbon chains having 7 to 17 carbon atoms.

Preferably, the Ra ^- C=O residue in formula (X) is derived from caprylic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, oleic acid, linoleic acid, linolenic acid or a mixture thereof. Preferably, the Ra ^- C=O residue in formula (X) is derived from coconut oil. Preferably, the Ra ^- C=O residue in formula (X) is derived from 9-decenoic acid, 9-dodecenoic acid or a mixture thereof.

The personal care or home care composition may for example comprise from 0.5 to 20 wt%, preferably from 1 to 10 wt%, more preferably from 2 to 5 wt% of a nonionic surfactant.

Amphoteric surfactants (zwitterionic surfactants) useful according to the present invention include betaines, amine oxides, alkylamidealkylamines, alkyl-substituted amino acids, acylated amino acids and biosurfactants.

Suitable betaines are alkyl betaines, alkyl amido betaines, imidazoline betaines, sulfobetaines (INCI sulfobetaines) and amidosulfobetaines and also phosphobetaines. Examples of suitable betaines and sulfobetaines are the following compounds named according to INCI: almond amidopropyl betaine, apricot amidopropyl betaine, avocado amidopropyl betaine, babassu amidopropyl betaine, behenamidopropyl betaine, behenyl betaine, betaine, canola amidopropyl betaine, capryloyl/caprylamidopropyl betaine, carnitine, cetyl betaine, cocamidoethyl betaine, cocamidopropyl Betaine, Cocamidopropyl Hydroxysultaine, Coco Betaine, Coco Hydroxysultaine, Coco/Oleamidopropyl Betaine, Coco-Sultaine, Decyl Betaine, Dihydroxyethyl Oleyl Glycinate, Dihydroxyethyl Soy Glycinate, Dihydroxyethyl Stearyl Glycinate, Dihydroxyethyl Tallow Glycinate, Dimethicone Propyl PG-Betaine, Erucamidopropyl Hydroxysultaine, Hydrogenated Tallow Betaine , Isostearamidopropyl Betaine, Lauramidopropyl Betaine, Lauryl Betaine, Lauryl Hydroxysulfobetaine, Lauryl Sulfobetaine, Milk Amidopropyl Betaine, Mink Oil Amidopropyl Betaine, Myristamidopropyl Betaine, Myristyl Betaine, Oleamidopropyl Betaine, Oleamidopropyl Hydroxysulfobetaine, Oleyl Betaine, Olive Amidopropyl Betaine, Palm Amidopropyl Betaine, Palmitic Acid Amidopropyl Betaine , palmitoyl carnitine, palm kernel amidopropyl betaine, PTFE acetoxypropyl betaine, ricinoleic acid amidopropyl betaine, sesame amidopropyl betaine, soya amidopropyl betaine, stearamidopropyl betaine, stearyl betaine, tallowamidopropyl betaine, tallowamidopropyl hydroxysultaine, tallow betaine, tallow dihydroxyethyl betaine, undecylenamidopropyl betaine and wheat germ amidopropyl betaine.

Suitable amine oxides according to the invention include the alkyl amine oxides, in particular the alkyl dimethyl amine oxides, the alkyl amido amine oxides and the alkoxy alkyl amine oxides.

Examples of suitable amine oxides are the following compounds named according to INCI: almond amidopropylamine oxide, babassu amidopropylamine oxide, behenamine oxide, cocamidopropylamine oxide, cocamide DEA oxide, cocoamine oxide, cocomorpholine oxide, decylamine oxide, decyltetradecylamine oxide, diaminopyrimidine oxide, dihydroxyethyl _C8 - _C10 alkoxypropylamine oxide, dihydroxyethyl _C9 - _C11 alkoxypropylamine oxide, dihydroxyethyl C12- _C15 alkoxypropylamine oxide, dihydroxyethyl cocoamine oxide, dihydroxyethyl laurylamine oxide, dihydroxyethyl stearamine oxide, dihydroxyethyl tallowamine oxide, hydrogenated palm kernel oil amine oxide, hydrogenated tallowamine oxide, hydroxyethyl hydroxypropyl _C12 - _{C15 15} Alkoxypropylamine Oxide, Isostearamidopropylamine Oxide, Isostearamidopropyl Morpholine Oxide, Lauramidopropylamine Oxide, Lauramine Oxide, Methylmorpholine Oxide, Milkamidopropylamine Oxide, Minkamidopropylamine Oxide, Myristamidopropylamine Oxide, Myristamine Oxide, Myristyl/Cetylamine Oxide, Oleamidopropylamine Oxide, Oleamine Oxide, Oliveamidopropylamine Oxide, Palmamidopropylamine Oxide, Palmitoylamine Oxide, PEG-3 Lauramine Oxide, Dihydroxyethyl Cocoamine Oxide Potassium Phosphate, Potassium Trisphosphonomethylamine Oxide, Sesame Amidopropylamine Oxide, Soybean Amidopropylamine Oxide, Stearamidopropylamine Oxide, Stearamine Oxide, Tallowamidopropylamine Oxide, Tallowamine Oxide, Undecylenamidopropylamine Oxide, and Wheatgerm Amidopropylamine Oxide.

Illustrative alkylamidoalkylamines are the following compounds according to the INCI nomenclature: Cocoamphodipropionic acid, cocobetainamidoamphopropionate, DEA cocoamphodipropionate, disodium capryloamphodiacetate, disodium capryloamphodipropionate, disodium capryloamphodiacetate, disodium capryloamphodipropionate, disodium cocoamphocarboxyethyl hydroxypropyl sulfonate, disodium cocoamphodiacetate, disodium cocoamphodipropionate, disodium isostearylamphodiacetate, disodium isostearylamphodiacetate. Disodium Laureth-5 Carboxyamphodiacetate Disodium Lauroamphodiacetate Disodium Lauroamphodiacetate Disodium Lauroamphodiacetate Disodium Oleoamphodiacetate Disodium PPG-2-Isodeceth-7 Carboxyamphodiacetate Disodium Stearoylamphodiacetate Disodium Tallowamphodiacetate Disodium Wheatgerm Oleoamphodiacetate Disodium Lauroamphodiacetate Quaternium-85 Capryloylamphodiacetate Sodium Acetate, Sodium Capryloamphohydroxypropyl Sulfonate, Sodium Capryloamphohydroxypropyl Sulfonate, Sodium Capryloamphohydroxypropyl Sulfonate, Sodium Capryloamphopropionate, Sodium Cocoamphoacetate, Sodium Cocoamphohydroxypropyl Sulfonate, Sodium Cocoamphopropionate, Sodium Cornamphopropionate, Sodium Isostearylamphoacetate, Sodium Isostearylamphopropionate, Sodium Lauroamphoacetate, Sodium Lauroamphohydroxypropyl Sulfonate, Sodium Lauroampho PG-Acetate Phosphate, Lauroamphopropyl The ingredients include sodium myristoamphoacetate, sodium oleoamphoacetate, sodium oleoamphohydroxypropyl sulfonate, sodium oleoamphopropionate, sodium ricinoleic acid amphoacetate, sodium stearoamphoacetate, sodium stearoamphohydroxypropyl sulfonate, sodium stearoamphopropionate, sodium tallowamphoacetate, sodium undecylenophoacetate, sodium undecylenophopropionate, sodium wheatgerm oleoamphoacetate, and sodium tri(lauroampho PG-acetate chloride) phosphate.

Illustrative alkyl-substituted amino acids are the following compounds named according to INCI: aminopropyl lauryl glutamine, cocoaminobutyric acid, cocoaminopropionic acid, DEA laurylaminopropionate, disodium cocoaminopropyliminodiacetate, disodium dicarboxyethyl cocopropylenediamine, disodium lauriiminodipropionate, disodium stearimidodipropionate, disodium tallowimidodipropionate, laurylaminopropionic acid, laurylaminopropyl glycine, lauryl diethylenediaminoglycine, myristic aminopropionic acid, sodium _C12 - _C15 alkoxypropyliminodipropionate, sodium cocoaminopropionate, sodium laurylaminopropionate, sodium laurimidodipropionate, sodium lauroylmethylaminopropionate, TEA laurylaminopropionate, and TEA myristic aminopropionate.

The personal care or home care composition may for example comprise from 0.5 wt% to 20 wt%, preferably from 1 wt% to 10 wt%, more preferably from 2 wt% to 5 wt% of amphoteric or zwitterionic surfactant.

In at least one embodiment, the personal care and home care compositions of the present invention comprise a total amount of surfactants from 0.01 wt% to 70 wt%, preferably from 0.1 wt% to 40 wt%, more preferably from 1 wt% to 30 wt%, particularly preferably from 2 wt% to 20 wt%.

The personal care or home care composition of the present invention may also include a glossing agent. Examples of suitable glossing agents include silicones. Examples of silicones are volatile or non-volatile nonionic silicone fluids, silicone resins, and silicone semi-solids or solids. Volatile silicones are linear or cyclic silicones with a measurable vapor pressure, which is defined as a vapor pressure of at least 2 mmHg at 20°C. Also suitable silicones are non-water-soluble, non-volatile silicone fluids, including polyalkylsiloxanes, polyarylsiloxanes, polyalkylarylsiloxanes, polyethersiloxane copolymers, amine-functional silicones, or mixtures thereof.

The personal care and home care compositions of the present invention may contain 0.05 to 5%, preferably 0.5 to 5% by weight of at least one oil component. Typical oils are organic oils, which are often esters. The oil component may contain glycerides or triglycerides of fatty acids, coconut oil, almond oil, apricot kernel oil, avocado oil, babassu oil, evening primrose oil, camelina seed oil, grape seed oil, macadamia seed oil, corn oil, meadowfoam seed oil, mink oil, olive oil, palm kernel oil, safflower oil, sesame oil, soybean oil, sunflower oil, wheat germ oil and camellia seed oil. Sorbitol esters are also suitable as oil components.

The personal care or home care composition of the present invention may contain 0.1 to 10 wt %, preferably 0.2 to 5 wt %, more preferably 0.2 to 3 wt %, still more preferably 0.5 to 5 wt % of at least one rheology modifier, in particular a gelling and thickening agent. Examples are cellulosic thickeners, for example, hydroxyethylcellulose, hydroxypropylcellulose and carboxymethylcellulose, guar gums such as hydroxypropyl guar, microbial derived gums such as xanthan gum and scleroglucan gum, and synthetic thickeners such as crosslinked homo- or copolymers of acrylic acid and/or acrylamidopropanesulfonic acid. Other rheology modifiers include fatty acid amides, for example coconut oil diethanolamide and monoethanolamide, and oxyethylated monoethanolamides of carboxylic acid alkyl ethers.

Rheology modifiers are also known as structural materials. Common structural materials include polymeric materials known as "carbomers," including, for example, those available from Lubrizol Corporation under the trade name Another class of (meth)acrylic acid polymers are alkali swellable emulsion (ASE) polymers. ASE polymers include, for example, 38 copolymers and ASE polymers belong to a class of materials known as hydrodynamic thickeners. These hydrodynamic thickeners include acid groups in their polymer structure, which, when deprotonated, form mutually repelling anionic charges, causing polymer chain swelling and entanglement. Swelling and chain entanglement can cause the thickening and suspension effects provided by the deprotonated polymers. The properties of these hydrodynamic thickeners are affected by their molecular weight, acid group content, degree of crosslinking, and degree of swelling. These thickeners are also known as "space filling" or "volume exclusion" and tend to increase both viscosity and yield point as their concentration increases. When used, hydrodynamic polymers generally produce compositions that exhibit shear thinning or non-Newtonian behavior. Another class of (meth)acrylic acid-based rheology modifiers are hydrophobically modified alkali swellable (HASE) polymers. Similar to ASE polymers, HASE polymers include acid groups, deprotonation of which causes the polymer to swell. Additionally, HASE polymers include hydrophobic side groups, chains or blocks that create bonding interactions with each other and with the hydrophobic groups of other hydrophobic materials used, such as surfactants, fatty acids and other thickeners, etc., present in the composition. The bonding creates hydrophobic regions distributed throughout the polymer chain network. This can also help enhance the material's properties as a solubilizing agent. 22 and 28 copolymer and Aqua SF from Lubrizol Copolymers are commonly used HASE materials. U.S. Pat. No. 4,529,773 (Witiak et al.) reports alkali-soluble emulsion polymers activated by neutralization to a pH above 6.5 and subsequently acidified in the presence of a surfactant. These are described as useful thickeners in acidic compositions. The polymers are formed by copolymerization of a monomer system comprising: (1) methacrylic acid or acrylic acid, (2) a C8-C30 alkyl methacrylate or acrylate, or, more particularly, a hydrocarbyl monoether of a polyethylene glycol, (3) a C1-C4 alkyl acrylate or methacrylate, and optionally (4) a small amount of a polyethylenically unsaturated monomer.

In at least one embodiment, the amount of rheology modifier, if not 0%, is preferably up to 5% by weight, more preferably 0.1% to 3% by weight, particularly preferably 0.5% to 2.5% by weight and very preferably 1% to 2% by weight, based on the total weight of the personal care or home care composition. In at least one embodiment, the amount of rheology modifier, if not 0%, is preferably up to 0.5% by weight, more preferably 0.001% to 0.3% by weight, particularly preferably 0.01% to 0.2% by weight and very preferably 0.01% to 0.15% by weight, based on the total weight of the personal care or home care composition. In at least one embodiment, the composition has a viscosity of 0 cPs to 20,000 cPs. In at least one embodiment, the composition has a viscosity of 0.1 cPs to 10,000 cPs, or 1 cPs to 5,000 cPs, or 5 cPs to 3,500 cPs.

It should be understood that the disclosed compositions may belong to more than one classification in some cases, for example, some fatty alcohol derivatives may also be classified as fatty acid derivatives. However, the given classification is not intended to limit a particular compound, but for ease of classification and naming. Non-limiting examples are shown in International Cosmetic Ingredient Dictionary and Handbook, Fourteenth Edition (2014) and CTFA Cosmetic Ingredient Handbook, Second Edition, 1992. Preferably, the fatty alcohol has 14 to 30 or 16 to 22 carbon atoms. These fatty alcohols are saturated and can be linear or branched. Examples of fatty alcohols are cetyl alcohol, stearyl alcohol, behenyl alcohol and mixtures thereof. Preferably, fatty acids have 10 to 30 or 12 to 22 carbon atoms. These fatty acids can be saturated and can be linear or branched. Salts of these fatty acids are also included herein. Examples of fatty acids are lauric acid, palmitic acid, stearic acid, behenic acid, sebacic acid or mixtures thereof.

In a preferred embodiment, the personal care or home care composition comprises a solvent selected from the group consisting of water, glycols, ethanol, and combinations thereof.

In a preferred embodiment, the personal care or home care composition comprises water, alcohol or a water-alcohol solvent, wherein the water, alcohol or water-alcohol solvent comprises water, ethanol, propanol, isopropanol, 1,2-propylene glycol, 1,3-propylene glycol, isobutanol, butanol, butanediol, butyldiglycol, glycerol or a mixture thereof; preferably wherein the water, alcohol or water-alcohol solvent comprises water, ethanol, propanol, isopropanol, 1,2-propylene glycol, 1,3-propylene glycol, glycerol or a mixture thereof; more preferably wherein the water, alcohol or water-alcohol solvent comprises water, isopropanol, 1,2-propylene glycol, 1,3-propylene glycol or a mixture thereof. Even more preferably wherein the water, alcohol or water-alcohol solvent consists of water or consists of a mixture of water and an alcohol, wherein the alcohol is selected from the group consisting of isopropanol, 1,2-propylene glycol and 1,3-propylene glycol.

Neutral solvents may also be used.In at least one embodiment, the personal care or home care composition comprises a solvent selected from the group consisting of vegetable oils, honey, plant-derived sugar compositions, and mixtures thereof.

In at least one preferred embodiment, the personal care or home care composition comprises at least one additive commonly found in the cosmetic, pharmaceutical and dermatological fields, hereinafter referred to as an adjuvant. In at least one preferred embodiment, the composition comprises an adjuvant. In at least one preferred embodiment, the adjuvant is cosmetically acceptable. In at least one preferred embodiment, the auxiliary agent is selected from the group consisting of waxes, surfactants, cationic polymers, film formers, superfatting agents, refatting agents, foam stabilizers, stabilizers, active biological substances, preservatives, preservative-promoting ingredients, antifungal substances, antidandruff agents, dyes or pigments, particulate matter, opacifiers, abrasives, absorbents, anti-caking agents, fillers, pearlescent agents, direct dyes, fragrances or aromas, carriers, solvents or diluents, propellants, functional acids, active ingredients, skin lighteners, self-tanning agents, exfoliants, enzymes, anti-acne agents, deodorants and antiperspirants, viscosity modifiers, thickeners and gelling agents, pH adjusters, buffers, antioxidants, chelating agents, astringents, sunscreens, sunscreens, UV filters, conditioning agents (e.g., hair conditioners or skin conditioners), emollients, moisturizers, occlusive agents, agents), anti-lice agents, defoaming agents, flavoring agents, electrolytes, oxidizing agents and reducing agents.

In at least one embodiment, the personal care or home care composition comprises water-soluble vitamins and their derivatives, water-soluble amino acids and their salts and/or derivatives, viscosity modifiers, dyes, non-volatile solvents or diluents (water-soluble and non-water-soluble), pearlescent aids, thickeners, foam boosters, additional surfactants or non-ionic co-surfactants, anti-lice agents, pH adjusters, fragrances, preservatives, chelating agents, proteins, skin active agents, sunscreens, UV absorbers, vitamins, niacinamide, caffeine, minoxidil, and combinations thereof. In at least one embodiment, the personal care composition comprises 0 wt % to 5 wt % vitamins and amino acids, based on the total weight of the composition. The personal care or home care composition may also comprise pigment materials such as inorganic, nitroso, monoazo, azine, carotenoids, triphenylmethane, triarylmethane, xanthene, quinoline, The personal care or home care composition may contain from 0 wt%, preferably from 0.0001 wt% to 5 wt% of pigment material.

In at least one embodiment, the personal care or home care composition comprises an oily substance, which is any fatty substance that is liquid at room temperature (25°C). In at least one embodiment, the personal care or home care composition comprises an oily substance selected from the following group: silicone oil, volatile or non-volatile, linear, branched or cyclic, optionally with an organic modifier; phenyl silicone; silicone resins and silicone gels; mineral oils such as paraffin oil or petrolatum; animal origin oils such as squalane, lanolin; vegetable origin oils such as liquid triglycerides, such as sunflower oil, corn oil, soybean oil, rice oil, jojoba oil, babassu oil (babusscu oil), pumpkin oil, grapeseed oil, sesame oil, walnut oil, apricot oil, macadamia oil, avocado oil, sweet almond oil, sorrel oil, castor oil, caprylic/capric triglycerides, olive oil, peanut oil, rapeseed oil, argan oil, camellia oil and coconut oil; synthetic oils such as pyogenic gland oil, isoparaffins, linear and/or branched fatty alcohols and fatty acid esters, preferably guerbet alcohols having 6 to 18, preferably 8 to 10, carbon atoms; esters of linear (C ₆ -C ₁₃ ) fatty acids with linear (C ₆ -C ₂₀ ) fatty alcohols; esters of branched (C ₆ -C ₁₃ ) carboxylic acids with linear (C ₆ -C ₂₀ ) fatty alcohols, linear (C ₆ -C ₁₈ ) fatty acids with branched alcohols, in particular 2-ethylhexanol; esters of linear and/or branched fatty acids with polyols (e.g. dimer glycol or trimer glycol) and/or Gibco alcohol; triglycerides based on (C ₆ -C ₁₀ ) fatty acids; esters such as dioctyl adipate, diisopropyl dimer linoleate; propylene glycol/dicaprylate or waxes such as beeswax, paraffin or microcrystalline wax, alone or in combination with a hydrophilic wax such as cetearyl alcohol; fluorinated or perfluorinated oils; fluorinated silicone oils; mixtures of the above-mentioned compounds.

In at least one embodiment, the personal care or home care composition comprises a nonionic coemulsifier. In at least one embodiment, the nonionic coemulsifier is selected from adducts of 0 to 30 mol of ethylene oxide and/or 0 to 5 mol of propylene oxide with linear fatty alcohols having 8 to 22 carbon atoms, with fatty acids having 12 to 22 carbon atoms, with alkylphenols having 8 to 15 carbon atoms in the alkyl group, and with sorbitol or sorbitol esters; (C ₁₂ -C ₁₈ ) fatty acid monoesters and diesters of adducts formed from 0 to 30 mol of ethylene oxide with glycerol; glycerol monoesters and diesters and sorbitol monoesters and diesters of saturated or unsaturated fatty acids having 6 to 22 carbon atoms and, where appropriate, their ethylene oxide adducts. Adducts of 15 to 60 mol of ethylene oxide with castor oil and/or hydrogenated castor oil; polyol esters and in particular polyglycerol esters, such as polyglycerol polyricinoleate and polyglycerol poly-12-hydroxystearate, for example. Likewise, mixtures of compounds from one or more of these classes of substances are suitable. Examples of suitable ionic coemulsifiers include anionic emulsifiers, such as mono-, di- or tri-phosphates, but also cationic emulsifiers such as mono-, di- or tri-alkyl quaternary ammonium salts (quats) and their polymer derivatives.

In at least one embodiment, the personal care or home care composition comprises a cationic polymer. Suitable cationic polymers include those known under the INCI name "polyquaternium", particularly polyquaternium-31, polyquaternium-16, polyquaternium-24, polyquaternium-7, polyquaternium-22, polyquaternium-39, polyquaternium-28, polyquaternium-2, polyquaternium-10, polyquaternium-11, and also include polyquaternium-37 & mineral oil & PPG tridecyl alcohol polyether (Salcare SC95), PVP-dimethylaminoethyl methacrylate copolymer, guar-hydroxypropyltrimonium chloride, and also include calcium alginate and ammonium alginate. It is also possible to use cationic cellulose derivatives; cationic starch; copolymers of diallyl ammonium salts and acrylamide; quaternized vinylpyrrolidone/vinylimidazole polymers; condensation products of polyglycols and amines; quaternized collagen polypeptides; quaternized wheat polypeptides; polyethyleneimine; cationic silicone polymers, such as amidomethicone; copolymers of adipic acid and dimethylaminohydroxypropyldiethylenetriamine; polyaminopolyamides and cationic chitin derivatives such as chitosan.

In at least one embodiment, the personal care or home care composition comprises a superfatting agent. As superfatting agents, substances such as polyethoxylated lanolin derivatives, lecithin derivatives, polyol fatty acid esters, monoglycerides and fatty acid alkanolamides may be used, the latter also serving as foam stabilizers. Useful humectants include, for example, isopropyl palmitate, glycerol and/or sorbitol.

In at least one embodiment, the personal care or home care composition comprises a care additive. The personal care or home care composition can be mixed with conventional ceramides, ceramide-like substances, fatty acid N-alkyl polyhydroxyalkylamides, cholesterol, cholesterol fatty acid esters, fatty acids, triglycerides, cerebrosides, phospholipids, panthenol and similar substances as care additives.

Functional acids are acidic substances used to impart clinical functions to the skin or hair when applied. Suitable functional acids include alpha-hydroxy acids, beta-hydroxy acids, lactic acid, retinoic acid and similar substances.

In at least one embodiment, the personal care or home care composition comprises an astringent. In at least one embodiment, the astringent is selected from the group consisting of magnesium oxide, aluminum oxide, titanium dioxide, zirconium dioxide, zinc oxide, oxide hydrates, aluminum oxide hydrates (boehmite) and hydroxides, chlorohydrates of calcium, magnesium, aluminum, titanium, zirconium or zinc. In at least one embodiment, the personal care or home care composition comprises 0.001 wt % to 10 wt %, or 0.01 wt % to 9 wt %, or 0.05 wt % to 8 wt %, or 0.1 wt % to 5 wt % of an astringent.

In at least one embodiment, the personal care composition comprises a deodorant. In at least one embodiment, the deodorant is selected from the group consisting of allantoin, bisabolol, and combinations thereof. In at least one embodiment, the personal care composition comprises 0.001 wt % to 10 wt %, or 0.01 wt % to 9 wt %, or 0.05 wt % to 8 wt %, or 0.1 wt % to 5 wt % of a deodorant.

In at least one embodiment, the personal care composition comprises a sunscreen and/or UV filter. Suitable sunscreens and/or UV filters are disclosed in WO-2013/017262A1, from page 32, line 11 to the end of page 33. In at least one embodiment, the sunscreen and/or UV filter is selected from the following group: 4-aminobenzoic acid, 3-(4'-trimethylammonium)-benzylidene-boran-2-one-methylsulfate, camphor benzalkonium methylsulfate, 3,3,5-trimethyl-salicylic acid cyclohexyl ester, 2-hydroxy-4-methoxybenzophenone, 2-phenylbenzimidazole-5-sulfonic acid and its potassium-, sodium- and triethanolamine salts, 3,3'-(1,4-phenylene disulfonic acid)-1,1-diol-2-one-methylsulfate, ... methyl)-bis-(7,7-dimethyl-2-oxobicyclo[2.2.1]-heptane-1-methylsulfonic acid) and its salts, 1-(4-tert-butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione, 3-(4'-sulfo)-benzylidene-bornane-2-one and its salts, 2-cyano-3,3-diphenyl-acrylate-(2-ethylhexyl) ester, polyacrylamide methylbenzylidene camphor (polymers of N-[2(and4)-(2-oxoborn-3-ylidenmethyl)benzyl]-acrylamide), 4-methoxy-cinnamic acid-2-ethyl-hexyl ester, ethoxylated ethyl-4-amino-benzoate, 4-methoxy-cinnamic acid-isoamyl ester, 2,4,6-tris-[p-(2-ethylhexyloxycarbonyl)anilino]-1,3,5-triazine, 2-(2H-benzotriazol-2-yl)-4-methyl-6-(2-methyl-3-(1,3,3,3-tetramethyl-1-(trimethylsilyloxy)-disilyl) -propyl)phenol, 4,4'-[(6-[4-((1,1-dimethylethyl)-amino-carbonyl)phenylamino]-1,3,5-triazine-2,4-yl)diimino]bis-(benzoic acid-2-ethylhexyl ester), 3-benzophenone, 4-benzophenone (acic), 3(4'-methylbenzylidene)-D,L-camphor, 3-benzylidene-camphor, salicylic acid-2-ethylhexyl ester, 4-dimethylaminobenzoic acid-2-ethylhexyl ester, hydroxy-4-methoxy-benzophenone-5-sulfonic acid and its sodium salt, 4-isopropylbenzyl alcohol salicylate, N,N,N-trimethyl-4-(2-o xoborn-3-methylenemethyl) anilium methylsulfate, homosalate (INN), oxybenzone (INN), 2-phenylbenzimidazole-5-sulfonic acid and its sodium, potassium and triethanolamine salts, octyl methoxycinnamic acid, isopentyl-4-methoxycinnamic acid, isopentyl-p-methoxycinnamic acid, 2,4,6-trianilino-(p-carbonyl (carbo)-2'-ethylhexyl-1'-oxy)-1,3,5-triazine (octyl triazine) phenol, 2,2 (2H-benzotriazol-2-yl)-4-methyl-6-(2-methyl-3-(1,3,3,3-tetramethyl 1-(trimethylsilyl)oxy)-dimethoxysilyl)propyl(drometrizole trisiloxane)benzoic acid, 4,4-((6-(((1,1-dimethylethyl)amino)carbonyl)phenyl)amino)-1,3,5-triazine-2,4-diyl)diimino)bis,bis(2-ethylhexyl)benzoate), 4,4-((6-(((1,1-dimethylethyl)amino)carbonyl)phenyl)amino)-1,3,5-triazine-2,4-diyl)diimino)bis,bis(2-ethylhexyl)benzoate), 3-(4'-tolylmethyl)-D,L-camphor(4-tolylmethyl) camphor), phenylmethylene-camphor-sulfonic acid, octocrylene, polyacrylamide methyl-benzylidene-camphor, 2-ethylhexyl salicylate (octyl salicylate), 4-dimethyl-aminobenzoic acid ethyl-2-hexyl ester (octyl dimethyl PABA), PEG-25 PABA, 2-hydroxy-4-methoxybenzo-phenone (phenone)-5-sulfonic acid (5-dibenzophenone) and its sodium salt, 2,2'-methylene-bis-6-(2H-benzotriazol-2-yl)-4-(tetramethyl-butyl)-1,1,3,3-phenol, 2-2'-bis-(1,4-phenylene) 1H-benzimidazole -4,6-disulfonic acid sodium salt, (1,3,5)-triazine-2,4-bis((4-(2-ethyl-hexyloxy)-2-hydroxy)-phenyl)-6-(4-methoxyphenyl), 2-ethylhexyl-2-cyano-3,3-diphenyl-2-acrylate, glyceryl caprylate, di-p-methoxycinnamic acid, p-amino-benzoic acid and its esters, 4-tert-butyl-4'-methoxydibenzoylmethane, 4-(2-β-pyranosyloxy)propoxy-2-hydroxybenzophenone, octyl salicylate, methyl-2,5-diisopropylcinnamic acid, cinoxate, dihydroxy-dimethoxybenzophenone ,2,2'-dihydroxy-4,4'-dimethoxy-5,5'-sulfonic acid benzophenone disodium salt, dihydroxybenzophenone, 1,3,4-dimethoxyphenyl-4,4-dimethyl-1,3-pentanedione, 2-ethylhexyl-dimethoxybenzylidene-dioxoimidazolinyl propionate, methylene-bis-benzotriazolyl tetramethylbutylphenol, phenyl dibenzimidazole tetrasulfonate, bis-ethylhexyloxyphenol-methoxyphenol-triazine, tetrahydroxybenzophenone, terephthalylidene dicamphor-sulfonic acid, 2,4,6-tri[4,2-ethylhexyl] [oxycarbonyl)anilino]-1,3,5-triazine, methyl-bis(trimethylsilyloxy)silyl-isoamyltrimethoxycinnamic acid, amyl-p-dimethylaminobenzoate, amyl-p-dimethylaminobenzoate, 2-ethylhexyl-p-dimethylaminobenzoate, isopropyl-p-methoxycinnamic acid/diisopropylcinnamic acid ester, 2-ethylhexyl-p-methoxycinnamic acid, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid and trihydrate, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid sodium salt, phenyl-benzimidazole sulfonic acid and combinations thereof. In at least one embodiment, the personal care composition comprises 0.001 wt % to 10 wt %, preferably 0.05 wt % to 5 wt %, even more preferably 0.1 wt % to 3 wt %, most preferably 0.05 wt % to 1 wt % of sunscreen and/or UV filter. In at least one embodiment, the personal care composition comprises an amount of light protection material of 0.01 to 10 wt %, or 0.1 to 5 wt %, more preferably 0.2 to 2 wt %. Suitable light protection materials include, in particular, all light protection materials specified in EP1084696A1 (L'OREAL), which is incorporated herein by reference. In a preferred embodiment, the light protection material is selected from the following group: 2-ethylhexyl 4-methoxycinnamate, methyl methoxycinnamate, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, polyethoxylated p-aminobenzoic acid esters and combinations thereof.

In at least one embodiment, the personal care or home care composition comprises an antioxidant. In at least one embodiment, the antioxidant is selected from the group consisting of amino acids, peptides, sugars, imidazoles, carotenoids, carotene, chlorogenic acid, lipoic acid, thiols, thioglycols, thioN-acetyl esters, thiomethyl esters, thioethyl esters, thiopropyl esters, thiopentyl esters, thiobutyl esters, thiolauryl esters, thiopalmitoyl esters, thiooleyl esters, thiolinoleyl esters, thiocholesterol esters, thioglycerides, dilauryl thiodipropionate, distearate thiodipropionate, thiodipropionic acid, metal chelates, hydroxy acids, fatty acids, folic acid, vitamin C, tocopherol, vitamin A, stilbenes, derivatives, and combinations thereof. In at least one embodiment, the antioxidant is selected from the group consisting of glycine, histidine, tyrosine, tryptophan, uric acid, D,L-carnosine, D-carnosine, L-carnosine, beta-carotene, alpha-carotene, lycopene, dihydrolipoic acid, gold thioglucose, propylthiouracil, thioredoxine, glutathione, cysteine, cystine, cystamine, buthioninsulfoximine, homocysteine sulfoximine, buthioninsulfoximine, amyl-, hexyl-, heptylthioninsulfoximine, hydroxy fatty acids, palmitic acid Acid, alginic acid, lactoferrin, citric acid, lactic acid, malic acid, humic acid, bile acid, bilirubin, biliverdin, EDTA, EGTA, linoleic acid, linolenic acid, oleic acid, butylhydroxyanisol, trihydroxybutyrophenone, ubichinon, ubichinol, ascorbyl palmitate, magnesium ascorbyl phosphate, ascorbyl acetate, vitamin E acetate, vitamin A palmitate, carnosine, mannose, ZnO, ZnSO4, methionine selenium, stilbenes, superoxide dismutase and combinations thereof. In at least one embodiment, the antioxidant is selected from the group consisting of vitamin A, vitamin A derivatives, vitamin E, vitamin E derivatives and combinations thereof. In at least one embodiment, the personal care composition comprises 0.001% to 10% by weight, preferably 0.05% to 5% by weight, even more preferably 0.1% to 3% by weight, and most preferably 0.05% to 1% by weight of an antioxidant.

In at least one embodiment, the personal care or home care composition comprises 0.01% to 10% by weight, preferably 0.05% to 5% by weight, of at least one particulate material. Suitable materials are, for example, materials that are solid and in particulate form at room temperature (25° C.). In at least one embodiment, the particulate material is selected from the following group: silica, silicates, aluminates, clays, mica, insoluble salts, in particular insoluble inorganic metal salts, metal oxides such as titanium dioxide, minerals and insoluble polymer particles are suitable. The particles can be present in the personal care or home care composition in an undissolved form, preferably in a stably dispersed form, and after application to a keratin matrix and evaporation of the solvent, can be deposited on the matrix in solid form. Stable dispersion is achieved by providing a personal care or home care composition with a yield point that is large enough to prevent the solid particles from sinking. A sufficient yield point can be established using a suitable amount of a suitable gel former. In at least one embodiment, the particulate material is selected from the following group: silicon oxide (silica gel, silicon dioxide) and metal salts, in particular inorganic metal salts, with silicon oxide being particularly preferred. The metal salt is, for example, an alkali metal or alkaline earth metal halide, such as sodium chloride or potassium chloride; an alkali metal or alkaline earth metal sulfate, such as sodium sulfate or magnesium sulfate.

Optionally, suitable additional disinfectants and/or preservatives according to the invention are, for example, active antimicrobial ingredients from the group consisting of alcohols, aldehydes, antimicrobial acids and their salts, carboxylates, amides, phenol, phenol derivatives, diphenyls, diphenylalkanes, urea derivatives, oxygen and nitrogen acetals and formaldehydes, benzamidine, isothiazoles and their derivatives such as isothiazolinones and isothiazolinones, phthalimide derivatives, pyridine derivatives, antimicrobial surface-active compounds, guanidines, antimicrobial amphoteric compounds, quinolines, 1,2-dibromo-2,4-dicyanobutane, iodo-2-propynylbutylcarbamate, iodine, iodophors and peroxides. Preferred active antimicrobial ingredients are preferably selected from the following group: ethanol, n-propanol, isopropanol, 1,3-butylene glycol, phenoxyethanol, 1,2-propylene glycol, glycerol, undecylenoic acid, citric acid, lactic acid, benzoic acid, salicylic acid, thymol, 2-benzyl-4-chlorophenol, 2,2'-methylenebis(6-bromo-4-chlorophenol), 2,4,4'-trichloro-2'-hydroxydiphenyl ether, N-(4-chlorophenyl)-N-(3,4-dichlorophenyl)urea, octenidine hydrochloride, chlorhexidine hydrochloride, antimicrobial quaternary surface active compounds, guanidine. Preferred antimicrobial surface active quaternary compounds contain ammonium, sulfonium, phosphinium, iodine or Groups, such as KH Described in "Praxis der Sterilization, Desinfektion-Konservierung: Keimidentifizierung-Betriebshygiene" [Practical Sterilization, Disinfection-Preservation: MicrobeIdentification-Commercial Hygiene] (5th ed. - Stuttgart; New York: Thieme, 1995).

In at least one embodiment, the personal care or home care composition comprises a conditioning agent. In at least one embodiment, the conditioning agent is a water-insoluble, water-dispersible, non-volatile liquid that forms emulsified liquid particles. In at least one embodiment, the conditioning agent is a silicone (e.g., silicone oil, cationic silicone, silicone rubber, high refractive index silicone and silicone resin), an organic conditioning oil (e.g., hydrocarbon oil, polyolefin and fatty ester), a cationic conditioning surfactant, a high melting point fatty compound or a combination thereof.

In at least one embodiment, the conditioning agent is a silicone. Preferably, the personal care or home care composition comprises 0.01% to 10%, or 0.1% to 5%, of a silicone conditioning agent based on the total weight of the composition. Suitable silicone conditioning agents and optional suspending agents for silicone are described in US-5104646. In at least one embodiment, the composition comprises a silicone rubber selected from the group consisting of polydimethylsiloxane, (polydimethylsiloxane) (methylvinylsiloxane) copolymer, poly(dimethylsiloxane) (diphenylsiloxane) (methylvinylsiloxane) copolymer, and mixtures thereof.

In at least one embodiment, the personal care or home care composition comprises a terminal amino silicone. "Terminal amino silicone" as defined herein means that the silicone comprises one or more amino groups at one or both ends of the silicone backbone. In at least one embodiment, the personal care or home care composition is substantially free of any organosilicon compound comprising a pendant amino group. In an embodiment, the personal care or home care composition is substantially free of any organosilicon compound other than terminal amino silicones. In at least one embodiment, the amino group at at least one end of the silicone backbone of the terminal amino silicone is selected from the group consisting of a primary amine, a secondary amine, and a tertiary amine. In at least one embodiment, the personal care or home care composition comprises a terminal amino silicone conforming to formula (S):

(R ^F ) _a G _3-a -Si-(OSiG ₂ ) _n -O-SiG _3-a (R ^F ) _a (S)

in

G is hydrogen, phenyl, hydroxy or C ₁ -C ₈ alkyl, preferably methyl;

a is an integer with a value from 1 to 3, preferably 1;

b is 0, 1 or 2, preferably 1

n is a number from 0 to 1999;

^RF is a monovalent group conforming _{to the general formula CqH2qL ,} wherein q is an integer with a value from 2 to 8 and L is selected from the following group: -N( ^RT ) _CH2 - _CH2 -N( ^RT ) ₂ ; -N( ^RT ) ₂ ; -N( ^RT ) _3A- ^; -N( ^RT ) _CH2 - _{CH2 -NRTH2A-} ^; wherein ^RT is hydrogen, phenyl, benzyl or a saturated hydrocarbon ^group , preferably an alkyl group having 1 to 20 carbon atoms; ^A- is a halide ion.

In at least one embodiment, the terminal amino silicone conforming to formula (S) has a=1, q=3, G=methyl, n is 1000 to 2500, or 1500 to 1700; and L is -N(CH ₃ ) ₂ . Suitable terminal amino silicone conforming to formula (S) has a=0, G=methyl, n is 100 to 1500, or 200 to 800, and L is selected from the following group: -N( ^RT )CH ₂ -CH ₂ -N( ^RT ) ₂ ; -N( ^RT ) ₂ ; -N( ^RT ) _3A ^- ; _-N ( ^RT )CH ₂ -CH ₂ ^{-NRTH2A -} ; wherein ^RT is hydrogen, phenyl, benzyl or a saturated hydrocarbon group, preferably an alkyl group having 1 to 20 carbon atoms; A ^- is a halide ion, or L is -NH ₂ . In at least one embodiment, the terminal amino silicone is selected from the group consisting of bis-aminomethyl dimethyl siloxane, bis-aminoethyl dimethyl siloxane, bis-aminopropyl dimethyl siloxane, bis-aminobutyl dimethyl siloxane, and mixtures thereof. In one embodiment, the viscosity of the terminal amino silicone measured at 25° C. is 1,000 to 30,000 cPs, or 5,000 to 20,000 cPs.

In at least one embodiment, the personal care or home care composition comprises from 0.1% to 20%, or from 0.5% to 10%, or from 1% to 6%, of amino-terminated silicone, based on the total weight of the composition.

In at least one embodiment, the personal care or home care composition comprises a high melting point fatty compound. The high melting point fatty compound has a melting point of 25°C or higher. In at least one embodiment, the high melting point fatty compound is selected from the following group: fatty alcohols, fatty acids, fatty alcohol derivatives, fatty acid derivatives and mixtures thereof. Non-limiting examples of high melting point compounds can be found in International Cosmetic Ingredient Dictionary (5th Edition, 1993) and CTFA Cosmetic Ingredient Handbook (2nd Edition, 1992). The composition may comprise 0.1% to 40%, or 1% to 30%, or 1.5% to 16%, or 1.5% to 8% of a high melting point fatty compound by weight of the total composition. This is advantageous from the perspective of providing an improved conditioning effect (e.g., a smooth feel during application to wet hair and a soft and moisturizing feel on dry hair). In at least one embodiment, the fatty alcohol is selected from the following group: cetyl alcohol, stearyl alcohol, behenyl alcohol and mixtures thereof. In at least one embodiment, the personal care or home care composition comprises a linear fatty alcohol, wherein the linear fatty alcohol is contained in a lamellar gel matrix. The lamellar gel matrix is suitable for providing various conditioning effects such as a smooth feel during application to wet hair and a soft and moisturizing feel on dry hair. The linear fatty alcohol may contain 8 to 24 carbon atoms. In one embodiment, the linear fatty alcohol is selected from the group consisting of cetyl alcohol, stearyl alcohol, and mixtures thereof. In one embodiment, the weight ratio of the linear fatty alcohol to the terminal amino silicone is 0.5:1 to 10:1, or 1:1 to 5:1, or 2.4:1 to 2.7:1. In at least one embodiment, the lamellar gel matrix comprises a cationic conditioning surfactant and a high melting point fatty compound. From the perspective of providing a lamellar gel matrix, the level of the cationic conditioning surfactant and the high melting point fatty compound included is a weight ratio of the cationic conditioning surfactant to the high melting point fatty compound in the range of 1:1 to 1:10 or 1:1 to 1:6.

In at least one embodiment, the personal care or home care composition comprises a cationic conditioning surfactant. In at least one embodiment, the personal care or home care composition comprises from 0.05% to 3.0%, or from 0.075% to 2.0%, or from 0.1% to 1.0% of a cationic conditioning surfactant, based on the total weight of the composition. In at least one embodiment, the cationic conditioning surfactant is contained in a lamellar gel matrix. In other words, the personal care or home care composition comprises a lamellar gel matrix and the lamellar gel matrix comprises a cationic conditioning surfactant.

In at least one embodiment, the cationic conditioning surfactant is according to formula (C):

wherein at least one of R ⁷¹ , R ⁷² , R ⁷³ and R ⁷⁴ is selected from an aliphatic group having 8 to 30 carbon atoms, an aromatic hydrocarbon, an alkoxy group, a polyoxyalkylene group, an alkylamino group, a hydroxyalkyl group, an aryl group, or an alkylaryl group having up to 22 carbon atoms; the remainder of R ⁷¹ , R ⁷² , R ⁷³ and R ⁷⁴ are each selected from the following groups: an aliphatic group having 1 to 22 carbon atoms, and an aromatic hydrocarbon, an alkoxy group, a polyoxyalkylene group, an alkylamino group, a hydroxyalkyl group, an aryl group, or an alkylaryl group having up to 22 carbon atoms; and X is selected from the following groups: halogen, acetate, citrate, lactate, glycolate, phosphate, nitrate, sulfonate, sulfate, alkyl sulfate, alkyl sulfonate and combinations thereof.

In at least one embodiment, the cationic conditioning surfactant is selected from the group consisting of behenyltrimethylammonium chloride, methyl sulfate or ethyl sulfate, and stearyltrimethylammonium chloride, methyl sulfate or ethyl sulfate. It is believed that the longer hydrocarbon groups provide improved smoothness and suppleness on wet or dry hair compared to cationic surfactants having short hydrocarbon groups. It is also believed that such cationic surfactants may provide reduced irritation compared to those cationic surfactants having short hydrocarbon groups.

In at least one embodiment, the cationic surfactant is a di-long alkyl quaternary ammonium salt selected from the following group: dialkyl (C14-C18) dimethyl ammonium chloride, ditallow alkyl dimethyl ammonium chloride, dihydrogenated tallow alkyl dimethyl ammonium chloride, distearyl dimethyl ammonium chloride, dicetyl dimethyl ammonium chloride and mixtures thereof.

In at least one embodiment, the cationic surfactant is a tertiary amidoamine having a hydrocarbon group of 12 to 22 carbon atoms, and the tertiary amidoamine can be selected from the following group: stearamidopropyl dimethyl-, stearamidopropyl diethyl-, stearamidoethyl diethyl-, stearamidoethyl dimethyl-, palmitamidopropyl dimethyl-, palmitamidopropyl diethyl-, palmitamidoethyl diethyl-, palmitamidoethyl dimethyl-, behenamidopropyl dimethyl-, behenamidopropyl diethyl-, behenamidoethyl diethyl-, behenamidoethyl dimethyl-, peanut amidopropyl dimethyl-, peanut amidopropyl diethyl-, peanut amidoethyl diethyl-, and peanut amidoethyl dimethyl-amine, and diethylamidoethyl stearylamine and mixtures thereof. The tertiary amidoamine can be used in combination with an acid. Typically the acid is used as a salt forming ion. In an embodiment, the acid is selected from the following group: lactic acid, malic acid, hydrochloric acid, 1-glutamic acid, acetic acid, citric acid and mixtures thereof.

In at least one embodiment, the cationic surfactant is selected from the group consisting of cetyltrimethylammonium chloride (CTAC), stearyltrimethylammonium chloride (STAC), behentrimonium methylsulfate, stearylamidopropyldimethylamine (SAPDMA), distearyldimethylammonium chloride, and mixtures thereof.

Optionally, the home care composition according to the invention may comprise one or more corrosion inhibitors. Suitable corrosion inhibitors (INCI corrosion inhibitors) are, for example, the following substances named according to INCI: cyclohexylamine, diammonium hydrogen phosphate, dilithium oxalate, dimethylaminomethyl propanol, dipotassium oxalate, dipotassium hydrogen phosphate, disodium hydrogen phosphate, disodium pyrophosphate, disodium tetrapropylene succinate, hexyloxyethyl diethyl ammonium, phosphates, nitromethane, potassium silicate, sodium aluminate, sodium hexametaphosphate, sodium metasilicate, sodium molybdate, sodium nitrite, sodium oxalate, sodium silicate, stearamidopropyl dimethicone, tetrapotassium pyrophosphate, tetrasodium pyrophosphate and triisopropanolamine.

The personal care and home care compositions of the present invention may further comprise fragrances. Useful fragrances are individual odorous compounds, such as synthetic products of esters, ethers, aldehydes, ketones, alcohols and hydrocarbons. The odorous compounds of the ester class are, for example, benzyl acetate, phenoxyethyl isobutyrate, p-tert-butylcyclohexyl acetate, linalyl acetate, dimethylbenzyl acetate, phenylethyl acetate, linalyl benzoate, benzyl formate, ethylmethylphenylglycinate, allyl cyclohexylpropionate, styryl propionate and benzyl salicylate. Ethers include, for example, benzyl ethyl ether, aldehydes include, for example, linear alkanals having 8 to 18 carbon atoms, citral, citronellal, citronellyl acetaldehyde, hydroxycitronellal, lily aldehyde and pogihon aldehyde, ketones include, for example, ionone, α-isomethyl ionone and methyl cedryl ketone, alcohols include anisol, citronellol, eugenol, geraniol, linalool, phenylethyl alcohol and terpineol; and hydrocarbons include mainly terpenes and balsams. It is preferred to use a mixture of different odorants that together give off a pleasant aroma. The fragrance used can also be a natural odor mixture, such as obtained from vegetable or animal sources, such as pine oil, citrus oil, jasmine oil, lily oil, rose oil or ylang-ylang oil. Essential oils with relatively low volatility, which are often used as fragrance ingredients, are also suitable for use as perfume oils, such as sage oil, chamomile oil, clove oil, melissa oil, peppermint oil, cinnamon leaf oil, linden flower oil, juniper berry oil, vetiver oil, frankincense oil, gabung oil and labdanum oil. The amount of the fragrance in the personal care or home care composition of the present invention, if not 0%, is preferably 0.001 wt% to 2 wt% and more preferably 0.01 wt% to 2 wt%, based on the total weight of the personal care or home care composition.

Any dyes and pigments are optionally present in the personal care or home care composition of the present invention, organic or inorganic dyes can be selected from the corresponding positive list of the Cosmetics Directive or the list of EU cosmetic colorants. Pearlescent pigments are also advantageously used, such as pearl essence (mixed guanine/hypoxanthine crystals from fish scales) and mother of pearl (ground sea shells), single-crystalline pearlescent pigments such as bismuth oxychloride (BiOCl), layer matrix pigments such as mica/metal _{oxides, silvery white pearlescent pigments composed of TiO2, interference pigments (TiO2, different layer thicknesses), color luster pigments (Fe2O3) and combination pigments (TiO2/Fe2O3 , TiO2 / Prussian blue , TiO2} /carmine). The amount of dyes and pigments in the personal care or home care composition of the present invention, if not 0%, is preferably _0.01 % to 1.0% by weight, based on the total weight of the personal care or home care composition.

In at least one embodiment, the personal care or home care composition comprises an alkalizing agent or pH adjusting agent. In at least one embodiment, ammonia or caustic soda is suitable, but water-soluble, physiologically tolerable salts of organic and inorganic bases are also contemplated. Optionally, the pH adjusting agent is selected from ammonium bicarbonate, ammonia, monoethanolamine, ammonium carbonate. In at least one embodiment, the alkalizing agent is selected from the group consisting of 2-amino-2-methyl-1-propanol, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-ethyl-1,3-propanediol, tris(hydroxy-methyl)-aminomethane, 2-amino-1-butanol, tris-(2-hydroxypropyl)-amine, 2,2-iminodiethanol, lysine, imine urea (guanidine carbonate), tetrahydro-1,4- Oxazine, 2-amino-5-guanidine-pentanoic acid, 2-aminoethanesulfonic acid, diethanolamine, triethanolamine, N-methylethanolamine, isopropanolamine, diisopropanolamine, triisopropanolamine, glucosamine, sodium hydroxide, potassium hydroxide, lithium hydroxide and magnesium oxide and mixtures thereof.

To establish an acidic pH, an acid may be included. In at least one embodiment, the personal care or home care composition comprises an acid selected from the group consisting of hydrochloric acid, phosphoric acid, acetic acid, formic acid, sulfuric acid, hydrochloric acid, citric acid, and mixtures thereof. Citric acid is most preferred due to its high consumer acceptance. In at least one embodiment, a buffer such as a phosphate buffer, a TRIS buffer, or a citric acid buffer is used to adjust the acidic pH. The buffer may be used alone or in combination with an acid.

The home care compositions of the present invention may optionally include conventional ingredients commonly used in detergent compositions, especially laundry detergent compositions. Examples of optional ingredients include, but are not limited to, builders, bleaching agents, bleach-active compounds, bleach activators, bleach catalysts, photobleaches, dye transfer inhibitors, color protectants, anti-redeposition agents, dispersants, fabric softeners, antistatic agents, fluorescent brighteners, enzymes, enzyme stabilizers, foam regulators, defoamers, deodorants, preservatives, disinfectants, hydrotropes, fiber lubricants, anti-shrinkage agents, buffers, fragrances, processing aids, colorants, dyes, pigments, corrosion inhibitors, fillers or stabilizers.

For improving detergency, it may be advantageous to use polymers in household care cleaning compositions, particularly in liquid laundry detergent compositions. The polymer is preferably a _{polyalkoxylated} polyethyleneimine (EPEI). Polyethyleneimine is a material consisting of ethyleneimine units _-CH2CH2NH- , and in the case of branches, the hydrogen on the nitrogen is replaced by another ethyleneimine unit chain. For example, these polyethylimines can be prepared by polymerizing ethylimine in the presence of a catalyst such as carbon dioxide, sodium bisulfite, sulfuric acid, hydrogen peroxide, hydrochloric acid, acetic acid, etc. Specific methods for preparing these polyamine backbones are disclosed in US 2,182,306, US 3,033,746, US 2,208,095, US 2,806,839 and US 2,553,696.

Home care cleaning compositions, especially liquid laundry detergent compositions may contain other polymeric materials, such as dye transfer inhibiting polymers, anti-redeposition polymers and cotton soil release polymers, especially those based on modified cellulose materials. In particular, in the absence of EPEI, the formulation may further contain a polymer of polyethylene glycol and vinyl acetate, such as the light graft copolymers described in WO 2007/138054. Such amphiphilic graft copolymers, based on water-soluble polyalkylene oxides as graft bases and side chains formed by polymerization of vinyl ester components, have the ability to reduce surfactant levels while maintaining high levels of oily soil removal.

In at least one embodiment, the personal care or home care composition comprises a hydrotrope. As used herein, a "hydrotrope" is a solvent that is neither water nor a conventional surfactant, and that can aid in the dissolution of the surfactant or other components, especially any polymers and/or chelating agents in the liquid, making them isotropic. Hydrotropes are particularly useful in home care cleaning compositions. Among suitable hydrotropes, the following are noteworthy: monopropylene glycol (MPG), glycerol, sodium cumene sulfonate, ethanol, other glycols such as dipropylene glycol, diethers, and ureas. MPG and glycerol are preferred hydrotropes.

In at least one embodiment, the composition includes a chelating agent, particularly a home care cleaning composition. Preferred chelating agents include organic phosphates, alkylhydroxyphosphates and carboxylates, such as are available from Thermphos under the DEQUEST trademark. Preferred chelating agent levels are less than 10 wt % and more preferably less than 5 wt %, based on the total weight of the composition. A particularly preferred chelating agent is HEDP (1-hydroxyethylidene-1,1-diphosphonic acid). For example, it is sold as Dequest 2010. 2066 (diethylenetriamine penta (methylenephosphonic acid or Heptasodium DTPMP) is also suitable. Complexing agents (INCI chelating agents), also known as sequestrants, are ingredients that are able to complex metal ions and inactivate them to prevent them from adversely affecting the stability or appearance of the composition (e.g. turbidity). Firstly, they are important for complexing calcium and magnesium ions of water hardness, which are incompatible with many ingredients. Then, complexing heavy metals such as ions of iron or copper delays the oxidative decomposition of the finished composition. In addition, complexing agents promote the action of detergents.

Suitable examples are the following complexing agents named according to INCI: aminotrimethylene, phosphonic acid, beta-alanine diacetate, calcium disodium EDTA, citric acid, cyclodextrin, cyclohexanediaminetetraacetic acid, diammonium citrate, diammonium EDTA, diethylenetriaminepentamethylenephosphonic acid, dipotassium EDTA, disodium azacycloheptane diphosphate, disodium EDTA, disodium pyrophosphate, EDTA, etidronic acid, galactaric acid, gluconic acid, glucuronic acid, HEDTA, hydroxypropyl cyclodextrin, methyl cyclodextrin, pentapotassium triphosphate, pentasodium aminotrimethylenephosphonate, pentasodium ethylenediaminetetramethylenephosphonate, pentasodium pentetate, pentasodium triphosphate, triaminepentaacetic acid, phytic acid, potassium citrate, potassium EDTMP, potassium gluconate, potassium polyphosphate, nitroglycerin, Potassium tri(methylene)triphosphonate N-oxide, ribonic acid, sodium chitosan methylenephosphonate, sodium citrate, sodium diethylenetriamine pentamethylenephosphonate, sodium dihydroxyethylglycinate, sodium EDTMP, sodium glucoheptonate, sodium gluconate, sodium glyceryl polyether-1 polyphosphate, sodium hexametaphosphate, sodium metaphosphate, sodium metasilicate, sodium phytate, sodium polydimethylglycinylphenolsulfonate, sodium trimetaphosphate, TEA-EDTA, TEA-polyphosphate, tetrahydroxyethylethylenediamine, tetrahydroxypropylethylenediamine, tetrapotassium etidronate, tetrapotassium pyrophosphate, tetrasodium EDTA, tetrasodium etidronate, tetrasodium pyrophosphate, tripotassium EDTA, trisodium dicarboxymethylalanine, trisodium EDTA, trisodium HEDTA, trisodium NTA and trisodium phosphate.

Optionally, bleaching agents may also be added to the home care composition. Suitable bleaching agents include peroxides, peracids and/or perborates, with H ₂ O ₂ being particularly preferred.

The home care composition of the present invention may also include enzymes, preferably proteases, lipases, amylases, hydrolases and/or cellulases. They may be added to home care compositions, particularly detergent compositions, in any form determined in the prior art. In the case where the detergent composition is in liquid or gel form, these particularly comprise enzyme solutions, advantageously at maximum concentration, with low water content and/or with added stabilizers. Alternatively, the enzyme may be encapsulated, for example by spray drying or extruding the enzyme solution together with a preferred natural polymer or in the form of capsules, for example, in the form of enzymes surrounded by a solidified gel or in the form of core-shell types, wherein the core containing the enzyme is coated with a water-, air- and/or chemical-impermeable protective layer. In the coating, further active ingredients may also be used, such as stabilizers, emulsifiers, pigments, bleaching agents or dyes. Such capsules are applied by known methods, for example, by stirring or drum granulation or fluidized bed processes. Advantageously, such pellets have low dust levels, for example, by using a polymeric film-forming agent, and the pellets are storage-stable due to coating.

Furthermore, in order to protect any enzymes present in the home care composition from damage, for example inactivation, denaturation or decomposition due to physical action, oxidation or cleavage of soluble proteins, enzyme stabilizers may be present in the enzyme-containing home care composition. Depending on the enzyme used in each case, suitable enzyme stabilizers are in particular: benzamidine hydrochloride, borax, boric acid, boric acid or its salts or esters, in particular derivatives with aromatic groups, such as substituted phenylboronic acid or its salts or esters; peptide aldehydes (oligomeric peptides with reduced carbon ends), amino alcohols such as mono-, di-, triethanol and -propanolamine and mixtures thereof, aliphatic carboxylic acids up to C ₁₂ such as succinic acid, other dicarboxylic acids or salts of the acids mentioned; terminally capped fatty acid amide alkoxylates; lower aliphatic alcohols, in particular polyols, such as glycerol, ethylene glycol, propylene glycol or sorbitol; and reducing agents and antioxidants such as sodium sulfite and reducing sugars. Further suitable stabilizers are known in the prior art. Preference is given to using combinations of stabilizers, for example combinations of polyols, boric acid and/or borax, combinations of boric acid or borates, reducing salts and succinic acid or other dicarboxylic acids, or combinations of boric acid or borates with polyols or polyamino compounds and reducing salts.

In at least one embodiment, personal or household care compositions, particularly liquid laundry detergent compositions, comprise buffering agents.Except optionally including reagents for the generation of anionic surfactants, the presence of a preferred buffering agent is used to control pH.Possible buffering agents are one or more ethanolamines, such as monoethanolamine (MEA) or triethanolamine (TEA).Preferably, the level at which they are used in the composition is 1.0 to 15 weight %.Other suitable amino alcohol buffering agents may be selected from the following group: compounds having a molecular weight greater than 61 g/mol, the compound comprising MEA.Except for the materials already mentioned, suitable materials also include: monoisopropanolamine, diisopropanolamine, triisopropanolamine, monoaminohexanol, 2-[(2-methoxyethyl) methylamino]-ethanol, propanolamine, N-methylethanolamine, diethanolamine, monobutanolamine, isobutanolamine, monoamylamine, 1-amino-3-(2-methoxyethoxy)-2-propanol, 2-methyl-4-(methylamino)-2-butanol and mixtures thereof. Potential alternatives to aminoethanol buffers are alkali metal hydroxides, such as sodium hydroxide or potassium hydroxide.

In at least one embodiment, the household care composition is a hand dishwashing composition. In at least one embodiment, the hand dishwashing composition comprises an anionic surfactant. In at least one embodiment, the hand dishwashing composition comprises 5% to 25% by weight of anionic surfactant. In at least one embodiment, the hand dishwashing composition comprises a surfactant system comprising at least one anionic surfactant and another surfactant selected from a nonionic surfactant, an amphoteric surfactant or a zwitterionic surfactant. Preferably, the hand dishwashing composition comprises cocamidopropyl betaine or an amine oxide. Preferred amine oxides are lauryl amine oxide, coconut oil base amine oxide or a combination thereof. In at least one embodiment, the pH value of the hand dishwashing composition is between pH 5.0 and pH 10, preferably pH 5.5 to 9.0. In the case where the hand dishwashing composition comprises an amine oxide, preferably the hand dishwashing composition has a pH between pH 7.5 and pH 9.5, most preferably pH 8.0 to pH 9.0.

In at least one embodiment, the home care composition is a hard surface cleaner. In at least one embodiment, the hard surface cleaner comprises an anionic surfactant. In at least one embodiment, the hard surface cleaner comprises 1 wt % to 10 wt % of anionic surfactant. In at least one embodiment, the hard surface cleaner comprises a nonionic surfactant. In at least one embodiment, the hard surface cleaner comprises 1 wt % to 10 wt % of a nonionic surfactant. In at least one embodiment, the hard surface cleaner comprises a surfactant system comprising at least one anionic surfactant and an additional surfactant selected from a nonionic surfactant, an amphoteric surfactant, a zwitterionic surfactant or a combination thereof. Preferably, the hard surface cleaner comprises a linear alkylbenzene sulfonate and a fatty alcohol ethoxylate. In at least one embodiment, the pH value of the hard surface cleaner is between pH 5.0 and pH 11, preferably pH 6.0 to pH 9.0.

In at least one embodiment, the home care composition is a liquid laundry detergent composition comprising one or more surfactants. Preferably, the one or more surfactants of the liquid laundry detergent composition are selected from the group consisting of anionic, nonionic, cationic and zwitterionic surfactants, and more preferably selected from the group consisting of anionic, nonionic and zwitterionic surfactants. Preferably, the one or more surfactants in the liquid laundry detergent composition are present in an amount of at least 5 wt%, more preferably from 5 wt% to 65 wt%, even more preferably from 6 to 60 wt%, and very preferably from 7 wt% to 55 wt%, based on the total weight of the liquid laundry detergent composition.

In at least one embodiment, the personal care or home care composition is in liquid form. In alternative embodiments, the personal care or home care composition is in solid form. Optionally, the personal care or home care composition is in powdered or granulated form. This is advantageous because there is no need to transport liquid (typically the liquid is very heavy when transported over long distances), so there is economic and environmental benefit. Solid form can be obtained by spray drying the composition or using a rotary evaporator. The personal care or home care composition can be converted into liquid form after it is transported, for example by adding water.

Exemplary personal care formulations comprising the antimicrobial composition are shown in Table 1 below.

Table 1: Personal care formulations containing antimicrobial compositions

Exemplary home care formulations comprising the antimicrobial composition are shown in Tables 2, 3 and 4 below.

Table 2: Hand dishwashing compositions containing antimicrobial compositions

Table 3: Hard surface cleaners containing antimicrobial compositions

Table 4: Laundry detergent compositions comprising antimicrobial compositions

The following examples are intended to illustrate the present invention without limiting the present invention thereby.

Example

Example 1 - Preparation of antimicrobial composition

At 25°C, 60 ml of DM water was added to the RBF and 20 g of L-arginine was added thereto. The mass was heated to 40°C and the reaction mixture was kept for 10 minutes or until a clear solution was obtained. 1.04 g of silver oxide was added to the above reaction mixture at 40-45°C and the mixture was kept at 40-45°C for 4 hours. The mass was cooled to 35°C and 700 ml of water was added thereto. Stirring was maintained at 30-35°C for 30 minutes. 2.5 g of octanoic acid was added at 30-35°C and stirring was maintained at the same temperature for 1 hour. The reaction mass was filtered using a hyflowbed at room temperature. RBF was washed with 90 ml of water and the solution was filtered through a hyflowbed. The silver content of the filtrate was determined and the final concentration of silver (0.09–0.11%) was adjusted by adding water.

The various amounts of silver oxide, arginine, caprylic acid and water are shown in Table 5 below.

Table 5

Example 7 - Determination of Silver Oxide Content

About 10.0 g of accurately weighed liquid sample of the antimicrobial composition of Examples E1-E6 was added to a 100-ml titration vessel with a mixture of 10 ml water and 5 ml concentrated nitric acid. The mixture was sonicated for 2.0 minutes and titrated using 0.05 N potassium thiocyanate by an automatic titrator (Metrohm 916 Ti Touch).

The silver oxide content in the sample was calculated using the following formula:

in,

V = volume of 0.05N potassium thiocyanate used for sample, ml

F = factor of 0.05N potassium thiocyanate used

W = weight of sample, g

The silver oxide content of antimicrobial compositions E1-E6 was determined and the results are shown in Table 6 below.

Table 6 - Silver oxide content of antimicrobial compositions

Example 8 - Testing the activity of antimicrobial compositions

For antimicrobial composition activity, the value determined is the minimum inhibitory concentration (MIC) of the antimicrobial agent necessary to reduce a known number of bacteria to zero after a specified contact time. Depending on the plating out method used, the percentage lethality for each individual organism or a group of organisms can also be determined (if necessary). Antimicrobial activity is tested according to BS EN1040.

in principle

Aliquots of known preservatives are dosed into weak nutrient solutions and cultured with known concentrations of microbial species. The microbial species can be a mixture of bacteria, yeasts or fungi or a single species. After a defined time interval, aliquots of the sample are plated and then the number of surviving species is determined using a smear plate method. By using a control that is not treated with a preservative, it can be determined that the preservative provides a level of zero growth.

Preparation of bacterial exposure inoculum

A loopful of bacteria was taken from an agar slants stored at 4°C, homogenized in 10 ml of tryptone soy broth, and incubated at 30°C ± 2.5°C (shaking at 150 rpm) for 16 hours. After this period, the solution was adjusted using the maximum recovery dilution to contain approximately 5×10 ⁵ viable cells/ml (overnight cultures contain approximately 1×10 9 cfu/ml, so this was used as a basis for calculating the dilutions required to produce the above inoculum levels). The actual number in the exposure inoculum was determined using standard spread plate count techniques.

Preparation of yeast and fungal cultures

Take a loopful of culture from a malt extract agar slants stored at 4°C and homogenize it in 10 ml of maximum recovery dilution. Vortex it for 30 seconds and adjust the suspension using maximum recovery dilution so that the solution contains approximately 5×10 ⁵ viable cells/ml. Use standard spread plate count techniques to determine the actual number in the inoculum.

The fungus was prepared by adding 10 ml of a 2% Tween solution to a malt extract slants stock culture and vortexing it for 30 seconds. The suspension was adjusted using the maximum recovery dilution so that the solution contained approximately 5 x 10 ⁵ viable spores/ml. The actual number in the inoculum was determined using a standard spread plate count technique.

Detailed setting method of MIC

Prepare a fresh preservative stock solution containing sterile phosphate slow release solution or other suitable diluent. Aseptically add sterile phosphate buffer and preservative solution to a sterile test tube according to Table 7. Incubate the test tube at a temperature appropriate for the test organism. At regular intervals, usually 1, 3, and 7 days, remove 0.1 ml aliquots from the test solution and plate them using the spread plate method. If necessary, a series of dilutions can be performed to more accurately determine the efficacy of the preservative.

Table 7 - Test tube compositions used to determine the minimum inhibitory concentrations of the named preservatives

*The above preservative concentrations assume a 10% preservative solution

The suitable temperature for in vitro culture is as follows:

30°C ± 2.5°C for bacterial cultures and 25°C ± 2.5°C for yeast/fungus cultures.

The fatality rate is calculated as follows:

Fatality rate: aging

General rules for log lethality:

1Log reduction = 90%

2Log reduction = 99%

3Log reduction = 99.9%

4Log reduction = 99.99%

5Log reduction = 99.999%

The MIC data of the antimicrobial compositions are shown in Table 8 below.

Table 8 - Minimum Inhibitory Concentration of Antimicrobial Compositions

Tested microorganisms E3(%) E4(%) Pseudomonas aeruginosa ATCC 9027 0.005 0.01 Staphylococcus aureus ATCC 6538 0.005 0.01 Escherichia coli ATCC 8 0.005 0.01 Candida albicans ATCC 1023 0.050 >0.10 Aspergillus niger ATCC 164 0.300 >0.20

Example 9 - Personal Care Compositions Containing Antimicrobial Compositions

The personal care compositions of the present invention comprising the antimicrobial composition were prepared according to Tables 9 and 10 below.

Table 9 - Hand/body wash containing antimicrobial compositions

Table 10 - Deodorants/antiperspirants containing antimicrobial compositions

Example 18 - Home Care Compositions Containing Antimicrobial Compositions

Home care compositions of the present invention comprising an antimicrobial composition were prepared according to Tables 11, 12 and 13 below.

Table 11 - Multi-Purpose Cleaners Containing Antimicrobial Compositions

Table 12 - Laundry detergent liquid compositions containing antimicrobial compositions

Table 13 - Fabric softeners containing antimicrobial compositions

*Based mainly on C16/18 saturated and unsaturated fatty acids of vegetable origin

Example 30 - Antimicrobial Efficacy of Personal or Home Care Compositions Containing Antimicrobial Compositions

The antimicrobial efficacy of the personal care and home care compositions of Examples 9-29 was determined using the method outlined above in Example 8. The results are shown in Table 14 below.

Table 14 - Antimicrobial Efficacy Data

in conclusion:

The data show that the antimicrobial composition has good efficacy against bacteria, yeasts and fungi. The composition is also stable over a wide pH range of 2.6 to 9.0 and is compatible in a variety of formulations.

Example 31 - Antimicrobial Composition Stability Study

The antimicrobial composition of E3 was used to study accelerated stability. Three 50 g samples were extracted from E3 and kept at a temperature of 40 ± 2 ° C and a humidity of 75 ± 5%. The stability was tested at time intervals of 0, 1, 3 and 6 months. The results are shown in Table 15 below.

Table 15

The personal care and home care compositions of the present invention comprising the antimicrobial composition remain stable for three months at room temperature and under accelerated stability conditions (as per Example 31) with no change in appearance, viscosity or pH.

Claims (14)

CLAIMS 1. An antimicrobial composition comprising at least one silver compound, at least one amino acid, at least one fatty acid and water. 2. The antimicrobial composition according to claim 1, wherein the silver compound is selected from the group consisting of silver oxide, silver halide, silver citrate, silver acetate, silver nitrate, silver carbonate, silver sulfate, silver sulfide, silver phosphate, benzene Silver formate, silver salicylate and mixtures thereof, preferably the silver compound is silver oxide. 3. The antimicrobial composition according to claim 1 or 2, wherein the silver compound is present at 0.01 to 0.3% by weight, based on the total weight of the antimicrobial composition. 4. The antimicrobial composition according to any one of claims 1 to 3, wherein the amino acid is selected from the group consisting of alanine, arginine, asparagine, aspartic acid, lysine, leucine, Isoleucine, Glycine, Glutamate, Serine, Threonine, Glutamine, Histidine, Methionine, Proline, Tyrosine, Cysteine, Phenylalanine, Tryptophan, Valine amino acids and mixtures thereof, preferably the amino acid is arginine. 5. The antimicrobial composition according to any one of claims 1 to 4, wherein the amino acid is present in an amount of 0.2 to 6% by weight, based on the total weight of the antimicrobial composition. 6. The antimicrobial composition according to any one of claims 1 to 5, wherein the fatty acid is an aliphatic acid with a carbon chain length of _C6 to _C22 . 7. The antimicrobial composition according to any one of claims 1 to 6, wherein the fatty acid is selected from caproic acid, heptanoic acid, octanoic acid, nonanoic acid, capric acid, undecanoic acid, dodecanoic acid, tridecanoic acid, Myristic acid, pentadecanoic acid, palmitic acid, heptadecanoic acid, behenic acid, octadecanoic acid, nonadecanoic acid, eicosic acid, behenic acid, myristoleic acid, palmitoleic acid, cis-6 -Hexadecenoic acid, elaidic acid, vaccenic acid, oleic acid, codoleic acid, eicosenoic acid, cis-13-eicosenoic acid, erucic acid, linoleic acid, eicosadiene acid, elaidic acid, docosadienoic acid, alpha- and gamma-linolenic acid, pinoleic acid, alpha- and beta-linoleic acid, eicosa-5,8,11-trienoic acid, bis Homo-gamma-linolenic acid, eicosa-11,14,17-trienoic acid, linolenic acid, arachidonic acid, eicosatetraenoic acid, adrenic acid, eicosa-5,8,10, 12,14-pentaenoic acid, eicosa-5,8,11,14,17-pentaenoic acid, docosapentaenoic acid, choic acid, docosahexaenoic acid and mixtures thereof, preferably The fatty acid is caprylic acid. 8. The antimicrobial composition according to any one of claims 1 to 7, wherein the fatty acid is present at 0.025 to 0.75% by weight, based on the total weight of the antimicrobial composition. 9. Use of an antimicrobial composition according to any one of claims 1 to 8 in a personal care or home care composition, preferably as an antimicrobial agent. 10. Use according to claim 9, wherein the personal care composition is a hand wash, body wash, deodorant or antiperspirant, and wherein the household care composition is a laundry detergent, fabric softener or All purpose cleaner. 11. A personal care or home care composition comprising the antimicrobial composition of any one of claims 1 to 8. 12. The personal care or home care composition according to claim 11, wherein said personal care or home care composition comprises 0.0001 to 10% by weight of said antimicrobial composition, based on said personal care or home care composition total weight of the object. 13. A personal care or home care composition according to claim 11 or 12, wherein said personal care composition is a hand wash, body wash, deodorant or antiperspirant, and wherein said home care composition is Laundry detergent, fabric softener or all-purpose cleaner. 14. A process for preparing the antimicrobial composition of any one of claims 1 to 8, wherein the composition is prepared by mixing at least one silver compound, at least one amino acid, at least one fatty acid and water .