CN1163768A - Pure Chinese medicine preparation for treating vitiligines - Google Patents
Pure Chinese medicine preparation for treating vitiligines Download PDFInfo
- Publication number
- CN1163768A CN1163768A CN 96118133 CN96118133A CN1163768A CN 1163768 A CN1163768 A CN 1163768A CN 96118133 CN96118133 CN 96118133 CN 96118133 A CN96118133 A CN 96118133A CN 1163768 A CN1163768 A CN 1163768A
- Authority
- CN
- China
- Prior art keywords
- grams
- radix
- pure chinese
- treating
- vitiligines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 7
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- 239000000843 powder Substances 0.000 claims abstract description 9
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims description 7
- 210000002826 placenta Anatomy 0.000 claims description 7
- 241000628997 Flos Species 0.000 claims description 5
- 210000000582 semen Anatomy 0.000 claims description 5
- 244000207740 Lemna minor Species 0.000 claims description 4
- 235000006439 Lemna minor Nutrition 0.000 claims description 4
- 235000001855 Portulaca oleracea Nutrition 0.000 claims description 4
- 241000209501 Spirodela Species 0.000 claims description 4
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 241000130781 Arnebia Species 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 235000014375 Curcuma Nutrition 0.000 abstract 1
- 244000164480 Curcuma aromatica Species 0.000 abstract 1
- 206010024380 Leukoderma Diseases 0.000 abstract 1
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 235000002020 sage Nutrition 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 9
- 210000004369 blood Anatomy 0.000 description 9
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 5
- 229910052802 copper Inorganic materials 0.000 description 5
- 239000010949 copper Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 4
- 230000001105 regulatory effect Effects 0.000 description 4
- 231100000957 no side effect Toxicity 0.000 description 3
- 229940098465 tincture Drugs 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 206010025421 Macule Diseases 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 206010047642 Vitiligo Diseases 0.000 description 2
- 238000011026 diafiltration Methods 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 230000004089 microcirculation Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 150000003254 radicals Chemical class 0.000 description 2
- 210000003491 skin Anatomy 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 description 1
- 206010048768 Dermatosis Diseases 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 241001446509 Psoralea Species 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000035614 depigmentation Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 230000002489 hematologic effect Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000001506 immunosuppresive effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 210000002752 melanocyte Anatomy 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000005325 percolation Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- -1 tabletting Substances 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A Chinese patent medicine for internal-use and external-use preparations for treating leukoderma with high cure rate and total effective rate and no toxic by-effect is prepared from 13 kinds of Chinese-medicinal materials such as violet sage root, safflower, curcuma root, human placeenta powder, arnebia lithosperm root, etc.
Description
The present invention relates to the leukodermic pure Chinese medicinal preparation of a kind of treatment.
Vitiligo is a kind of refractory dermatosis of depigmentation, and existing medicine majority is to control table not effect a permanent cure, so curative effect is undesirable, and majority has side effect, and not seeing at present has pure Chinese medicinal preparation.
The object of the present invention is to provide a kind of therapeutic effect good, no side effects, can side's dual-purpose the pure Chinese medicinal preparation of (for oral administration, as to put on the skin outward).
The object of the present invention is achieved like this: exist some immunologic function disorder and local organization blood microcirculation to change according to patients with vitiligo, primary disease is proposed except that the mechanism that QI and blood is become estranged, sick for a long time with deficiency of the liver and kindey and prolonged illness must the stasis of blood principle, on prescription, strive vigorously to advocate and start with, hold concurrently to grow the Therapeutic Principle of liver and kidney tonifying from QI and blood regulating.
Comprise in the medicine of the present invention (weight portion): Radix Salviae Miltiorrhizae 2-4, duckweed spirodela 1-3, Bornitum 0.4-0.8, Flos Carthami 1-3, Radix Curcumae 1-3, Placenta Hominis powder 1-3, Radix Arnebiae (Radix Lithospermi) 1-3, Herba Siegesbeckiae 1-3, Fructus Tribuli 2-4, Semen Juglandis 1-3, Caulis Spatholobi 2-4, rust 0.1-0.3, Fructus Jujubae 0.5-1.5.
Chinese medicine of the present invention adopts two doses of sides, dosage form promptly for oral administration and exterior-applied formulation, and dosage form for oral administration can adopt tablet, pill, capsule etc., and exterior-applied formulation can adopt tincture, to realize that internal and external treatment combines.
In this prescription, Radix Salviae Miltiorrhizae has the expansion peripheral vessels, promotes tissue regeneration, improves SOD activity in the blood; Herba Spirodelae, red copper have that QI and blood regulating is moved, invigorated blood circulation, the blood stasis dispelling function; Herba Siegesbeckiae has immunosuppressive activity; Flos Carthami, Radix Curcumae, Caulis Spatholobi, Fructus Tribuli, Radix Arnebiae (Radix Lithospermi), rust etc. can QI and blood regulating; Semen Juglandis, Placenta Hominis can nourishing the liver and kidney.By liver and kidney tonifying, improve body free radical resisting function, stoped the melanocytic destruction of radical pair effectively, thereby white macula position melanocyte and melanin granule are recovered; By QI and blood regulating, with the microcirculation improvement obstacle, make local blood supply abundance, for melanocytic reparation and functional activity provide necessary nutrition, make white macula be gone back the skin true qualities.
The present invention is through clinical trial, and contrasts with existing consistent 8-methoxyl group Fructus Psoraleae sheet and psoralea tincture of generally acknowledging, no matter the aspect all has clear superiority improving clinical cure rate and total effective rate and have no side effect etc.
The clinical comparison result of the test
| The example number | Total effective rate | Cure rate | Toxic and side effects | |
| The present invention | ??197 | ??93.4％ | ??23.3％ | Have no side effect |
| Matched group | ??131 | ??64.1％ | ??5.3％ | The heart, liver, kidney and hematological function infringement |
Embodiment 1: red copper disappears white
Radix Salviae Miltiorrhizae 150 grams, duckweed spirodela 100 grams, Bornitum 20 grams, Flos Carthami 100 grams, Radix Curcumae 100 grams, Placenta Hominis powder 100 grams, Radix Arnebiae (Radix Lithospermi) 100 grams, Herba Siegesbeckiae 100 grams, Fructus Tribuli 150 grams, Semen Juglandis 100 grams, Caulis Spatholobi 150 grams, rust 10 grams, Fructus Jujubae 50 grams.The red copper, Placenta Hominis powder, the rust that make are ground into fine powder, and the medicinal decocting of all the other 10 flavors boils twice, and each 1.5 hours, collecting decoction, filter, be condensed into thick paste, adding red copper, Placenta Hominis powder, iron rust and dextrin are an amount of, mixing, granulate, tabletting, coating gets 500 in tablet.Embodiment 2: the red copper white tincture that disappears
Radix Salviae Miltiorrhizae 150 grams, duckweed spirodela 100 grams, Bornitum 20 grams, Flos Carthami 100 grams, Radix Curcumae 100 grams, Placenta Hominis powder 100 grams, Radix Arnebiae (Radix Lithospermi) 100 grams, Herba Siegesbeckiae 100 grams, Fructus Tribuli 150 grams, Semen Juglandis 100 grams, Caulis Spatholobi 150 grams, rust 10 grams, Fructus Jujubae 50 grams.Above medicine is ground into coarse powder, put in the diafiltration tube, make solvent with 65% ethanol of triplication by percolation, flood after 24 hours, with the slowly diafiltration of speed of per minute 5-8ml, collect percolate, residue is put in the centrifuge and is dried, merge percolate and centrifugal liquid, add 60% ethanol, azone is to 500ml, cold preservation 48 hours, filter, packing gets final product.
Claims (1)
1. the leukodermic pure Chinese medicinal preparation of treatment is characterized in that:
Comprise (weight portion) in the medicine: Radix Salviae Miltiorrhizae 2-4, duckweed spirodela 1-3, Bornitum 0.4-0.8, Flos Carthami 1-3, Radix Curcumae 1-3, Placenta Hominis powder 1-3, Radix Arnebiae (Radix Lithospermi) 1-3, Herba Siegesbeckiae 1-3, Fructus Tribuli 2-4, Semen Juglandis 1-3, Caulis Spatholobi 2-4, rust 0.1-0.3, Fructus Jujubae 0.5-1.5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96118133 CN1163768A (en) | 1996-04-30 | 1996-04-30 | Pure Chinese medicine preparation for treating vitiligines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96118133 CN1163768A (en) | 1996-04-30 | 1996-04-30 | Pure Chinese medicine preparation for treating vitiligines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1163768A true CN1163768A (en) | 1997-11-05 |
Family
ID=5124821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 96118133 Pending CN1163768A (en) | 1996-04-30 | 1996-04-30 | Pure Chinese medicine preparation for treating vitiligines |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1163768A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103189767A (en) * | 2011-08-26 | 2013-07-03 | 株式会社藤仓 | Optical fiber, optical transmission path, and optical fiber manufacturing method |
-
1996
- 1996-04-30 CN CN 96118133 patent/CN1163768A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103189767A (en) * | 2011-08-26 | 2013-07-03 | 株式会社藤仓 | Optical fiber, optical transmission path, and optical fiber manufacturing method |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |