CN116350303A - Thrombectomy device - Google Patents

Abstract

The invention discloses a thrombus removal device, comprising: a suction catheter for sucking thrombus; a filter assembly, the filter assembly is arranged in the suction catheter and can move along the axial direction parallel to the suction catheter , the distal end of the filter assembly can protrude from the distal end of the suction catheter during the axial movement of the filter assembly; the filter assembly includes a delivery tube and a filter screen; the delivery tube is accommodated in the suction In the suction catheter and can move along the axial direction parallel to the suction catheter and the distal end of the delivery tube can protrude from the distal end of the suction catheter; the distal end of the delivery tube has a a contracted first state when inside and a second expanded state when positioned outside the suction catheter; the filter screen is connected to the distal end of the delivery tube such that the filter screen is The first state and the second state are tightened and unfolded. The present invention aims at at least solving the problem of escape of dislodged thrombus.

Description

Thrombectomy device

technical field

The invention belongs to the technical field of medical devices, and in particular relates to a thrombectomy device.

Background technique

A thrombus is a small block formed by blood flow on the surface of a peeled or repaired vascular intima in the cardiovascular system, consisting of insoluble fibrin, deposited platelets, accumulated white blood cells, and trapped red blood cells. At present, the methods for the treatment of thrombus mainly include drug antithrombotic therapy and artificial mechanical methods to physically restore the patency of blood vessels. It is metabolized and excreted in the human body. Therefore, the concentration of antithrombotic drugs in the blood vessels is relatively low. Antithrombotic drugs have the disadvantages of slow action and effect, and cannot be used to rescue acute myocardial infarction, cerebrovascular infarction, acute For acute thrombotic diseases such as deep vein thrombosis of the lower extremities, physical thrombectomy can only be used for such diseases.

There are already thrombus aspiration catheters on the market that can slow down a clot that blocks blood flow and restore blood supply. However, when the existing thrombus suction catheter sucks the thrombus, after the stable thrombus is loosened, the thrombus escapes, and escapes to the small blood vessel with the blood flow, causing the blockage of the downstream blood vessel and causing new thrombus to occur; Thrombus suction, large thrombus will block the suction port, resulting in the need to remove the thrombus suction catheter and send it back into the human body, prolonging the operation time and increasing the difficulty of the operation; for sub-thrombosis or old thrombus, tightly adsorb On the vessel wall, ordinary suction may not be able to aspirate, resulting in failure of the operation.

Contents of the invention

It is an object of the present invention to at least solve the problem of escape of dislodged thrombus. This purpose is achieved by:

The present invention proposes a thrombectomy device, comprising:

Suction catheter, used to aspirate blood clots;

a filter assembly, the filter assembly is arranged in the suction conduit and can move in an axial direction parallel to the suction conduit, and the distal end of the filter assembly can be extended during the axial movement of the filter assembly the distal end of the suction catheter;

The filter assembly includes a delivery tube and a filter screen; the delivery tube is accommodated in the suction catheter and can move along the axial direction parallel to the suction catheter, and the distal end of the delivery tube can extend out of the suction catheter. The distal end of the suction catheter; the distal end of the delivery tube has a first state contracted when located inside the suction catheter and a second state expanded when located outside the suction catheter; the filter mesh is connected to the and the distal end of the delivery tube such that the strainer tightens and expands with the first and second positions of the delivery tube.

In some embodiments of the present invention, the delivery pipe is provided with a spray channel and the distal end of the delivery tube is provided with a spray hole that communicates with the spray channel. In the second state, the spray hole is connected to the spray channel The suction ports of the suction catheters are opposite.

In some embodiments of the present invention, the distal end of the delivery pipe is provided with an annular portion, the inner ring of the annular portion is provided with part of the injection channel, and the annular portion is provided with a hole that communicates with the injection channel. the orifice.

In some embodiments of the present invention, the annular portion includes an annular pipe and at least one injection pipe, the proximal end of the filter screen is connected to the annular pipe, and the distal end of the filter screen is connected to the delivery pipe. The distal ends are arranged at intervals, the two ends of the injection pipe are respectively connected with the ring pipe, and the spray holes are arranged on the injection pipe and/or the ring pipe.

In some embodiments of the present invention, the filter assembly further includes a drawing wire, one end of the drawing wire is arranged inside the annular portion, and the other end of the drawing wire passes out to the outside of the suction catheter.

In some embodiments of the present invention, a part of the wire-drawing channel is arranged inside the annular part, and the part of the wire-drawing channel is arranged on the outside of the injection channel along the radial direction or the part of the wire-drawing channel is arranged along the axial direction. It is arranged at the far end side of the injection channel, and one end ring of the wire drawing is arranged inside the part of the wire drawing channel.

In some embodiments of the present invention, a suction cavity is provided inside the suction catheter along the axial direction, and the drawing wire and the conveying tube are jointly provided in the suction cavity and arranged side by side.

In some embodiments of the present invention, the inside of the suction catheter is provided with a suction cavity and a push cavity along the axial direction, the suction cavity and the push cavity are arranged side by side, and the drawing wire and the delivery tube jointly set in the pushing chamber.

In some embodiments of the present invention, the delivery tube further includes a tubular main body, the distal end of the tubular main body is connected to the annular portion, and the tubular main body includes an inner tube and a sleeve sleeved outside the inner tube. An outer tube, another part of the injection channel is formed inside the inner tube, and another part of the drawing channel is formed between the inner tube and the outer tube.

In some embodiments of the present invention, the distal end surface of the pushing chamber is flush with the distal end surface of the suction chamber, or the distal end surface of the pushing chamber is lower than the distal end surface of the suction chamber. Set close to the proximal end of the suction catheter, or the distal end surface of the push cavity is farther away from the proximal end of the suction catheter than the distal end surface of the suction cavity

In some embodiments of the present invention, the thrombectomy device further includes a suction catheter base, and a rotatable first adjustment knob and a second adjustment knob are arranged on the suction catheter base, and the first adjustment knob and the second adjustment knob are connected to each other. The delivery tube is connected to drive the delivery tube to move along the axial direction of the suction catheter, and the second adjustment knob is connected to the drawing wire and is used to drive the drawing wire to move along the axial direction of the suction catheter. Axial direction movement.

In some embodiments of the present invention, the suction port at the distal end of the suction catheter is in a wedge-shaped structure inclined relative to its axis, and the wedge-shaped structure has a wedge angle ranging from 10° to 40°.

In the thrombectomy device of the present invention, the filter assembly is contracted and can be moved on the side of the suction catheter. When in use, the filter assembly can extend out of the distal end of the suction catheter in parallel and expand, and the filter screen will expand with the expansion. It can effectively collect the fallen thrombus, prevent the thrombus from escaping, and improve the collection effect. Since the filter assembly is located at the side of the suction catheter, it will not occupy the effective suction section of the suction port and will not affect the suction of the inclined setting. The mouth is blocked, which can further ensure the suction effect. In addition, a spray channel is provided in the delivery tube, and the nozzle hole at the far end of the delivery tube in the expanded filter assembly is opposite to the suction port of the suction catheter, so that the liquid sprayed through the delivery tube can be used for the suction of the suction catheter. The nozzle is sprayed, so as to effectively crush the large thrombus blocked at the suction port, and prevent the large thrombus from blocking the suction port during the thrombus suction process, so that continuous suction can be realized. In addition, when the sprayed liquid is medicinal liquid, the ejected medicinal liquid can soften the thrombus firmly adsorbed on the blood vessel wall, which helps the thrombus to fall off from the blood vessel wall, further improving the suction and collection effect.

Description of drawings

Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiment. The drawings are only for the purpose of illustrating a preferred embodiment and are not to be considered as limiting the invention. Also throughout the drawings, the same reference numerals are used to denote the same parts. in:

Fig. 1 is a partial structural schematic diagram of the thrombectomy device when the distal end of the delivery tube is in the first state according to Embodiment 1 of the present application;

Fig. 2 is a partial structural schematic diagram when the distal end of the delivery tube in Fig. 1 is outside the suction catheter and is not expanded;

Fig. 3 is a partial structural schematic view when the distal end of the delivery tube in Fig. 2 is outside the suction catheter and expanded;

Fig. 4 is a schematic sectional structure diagram of section A-A in Fig. 3;

Fig. 5 is a schematic sectional structure diagram of section B-B in Fig. 3;

Fig. 6 is a schematic sectional structure diagram of section C-C in Fig. 3;

FIG. 7 is a schematic diagram of an enlarged structure of part D in FIG. 3;

Fig. 8 is a partial structural schematic view of the delivery tube according to Embodiment 2 of the present application when the distal end is outside the suction catheter and expanded;

Fig. 9 is a schematic cross-sectional structure diagram of section E-E in Fig. 8;

Fig. 10 is a partial structural schematic view of the third embodiment of the present application when the distal end of the delivery tube is outside the suction catheter and expanded;

Fig. 11 is a schematic cross-sectional structure diagram of section F-F in Fig. 10;

FIG. 12 is a schematic cross-sectional structure diagram of section G-G in FIG. 10 .

Each label in the accompanying drawing represents as follows:

1: Thrombectomy device;

10: suction catheter, 11: suction cavity, 12: push cavity, 13: guide wire cavity;

20: filter assembly, 21: conveying pipe, 211: annular part, 2111: ring pipe, 21111: injection channel, 21112: drawing channel, 2112: injection pipe, 21121: injection hole, 212: tubular main body, 2121: inner tube , 2122: outer tube, 22: filter screen, 23: wire drawing;

30: Suction Catheter Base, 31: Base Body, 32: First Adjustment Knob, 33: Second Adjustment Knob, 311: Suction Connector, 312: Injection Solution Connector, 313: Guide Wire Connector;

40: developing parts.

Detailed ways

Exemplary embodiments of the present invention will be described in more detail below with reference to the accompanying drawings. Although exemplary embodiments of the present invention are shown in the drawings, it should be understood that the invention may be embodied in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided for more thorough understanding of the present invention and to fully convey the scope of the present invention to those skilled in the art.

It should be understood that the terminology used herein is for the purpose of describing particular example embodiments only and is not intended to be limiting. As used herein, the singular forms "a", "an" and "the" may also be meant to include the plural forms unless the context clearly dictates otherwise. The terms "comprising", "comprising", "containing" and "having" are inclusive and thus indicate the presence of stated features, steps, operations, elements and/or parts but do not exclude the presence or addition of one or Various other features, steps, operations, elements, components, and/or combinations thereof. The method steps, processes, and operations described herein are not to be construed as necessarily requiring their performance in the particular order described or illustrated, unless an order of performance is specifically indicated. It should also be understood that additional or alternative steps may be used.

Although the terms first, second, third, etc. may be used herein to describe various elements, components, regions, layers and/or sections, these elements, components, regions, layers and/or sections should not be referred to as These terms are limited. These terms may be only used to distinguish one element, component, region, layer or section from another region, layer or section. Terms such as "first," "second," and other numerical terms when used herein do not imply a sequence or order unless clearly indicated by the context. Thus, a first element, component, region, layer or section discussed below could be termed a second element, component, region, layer or section without departing from the teachings of the example embodiments.

For the convenience of description, spatial relative terms may be used herein to describe the relationship of one element or feature as shown in the figures with respect to another element or feature, such as "inner", "outer", "inner". ", "Outside", "Below", "Below", "Above", "Above", etc. Such spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "below" or "beneath" other elements or features would then be oriented "above" or "beneath" the other elements or features. feature above". Thus, the example term "below" can encompass both an orientation of above and below. The device may be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

In order to describe the structure of the present application more clearly, the terms "proximal end" and "distal end" are defined here as commonly used terms in the field of interventional medicine. Specifically, "distal end" refers to the end away from the operator during the operation, "proximal" refers to the end close to the operator during the operation, "axial" refers to its length direction, and "radial" refers to the end perpendicular to the "Axial" direction.

The present invention provides a thrombus removal device, which includes a suction catheter and a filter assembly, wherein the suction catheter is used to suck thrombus, and the filter assembly is used to capture thrombus downstream of the suction port of the suction catheter. Specifically, the filter assembly is arranged in the suction conduit and can move along the axial direction parallel to the suction conduit, and the distal end of the filter assembly can extend out of the distal end of the suction conduit during the axial movement of the filter assembly; the filter assembly includes Delivery tube and filter screen; the delivery tube is accommodated in the suction catheter and can move along the axial direction parallel to the suction catheter and the distal end of the delivery tube can extend out of the distal end of the suction catheter; the distal end of the delivery tube has a The first state of contraction when inside the suction catheter and the second state of expansion when outside the suction catheter; the proximal end of the filter screen is connected to the far end of the delivery tube, and the distal end of the filter screen is spaced apart from the far end of the delivery tube, The filter screen is tightened and unfolded according to the first state and the second state of the delivery tube, and the filter screen captures the thrombus in the expanded state of the filter screen. The filter screen of the present invention is directly tightened or unfolded with the forward and backward movement of the self-expandable delivery tube, has a fast response speed, and does not require other additional supporting structures, and the overall structure is simple and easy to operate. In addition, the distance between the distal end of the filter screen and the delivery tube prevents the end of the delivery tube from entering the filter screen, effectively ensuring the collection space inside the filter screen, and at the same time ensuring the flexibility of the distal end of the thrombectomy device as much as possible. Implementation Mode 1

Based on the above thrombectomy device, this embodiment exemplarily provides a specific implementation manner of the thrombus retrieval device. As shown in FIG. 1 to FIG. 3 , the thrombus retrieval device 1 of this embodiment includes a suction catheter 10 and a filter assembly 20 . The suction catheter 10 is used to suck thrombus, and has a suction lumen inside, and a suction port at its distal end. The filter assembly 20 is arranged in the suction catheter 10 and can move along the axial direction parallel to the suction catheter 10. During the axial movement of the filter assembly 20, the distal end of the filter assembly 20 can protrude from the distal end of the suction catheter 10. . Wherein, the filter assembly 20 is located at the side of the catheter 10 to avoid the suction cavity as much as possible.

The filter assembly 20 includes a delivery tube and a filter screen; the delivery tube is housed in the side portion of the suction catheter and can move along the axial direction parallel to the suction catheter and the distal end of the delivery tube can extend out of the suction catheter distal end; the distal end of the tube has a first contracted state when positioned within the suction catheter and a second expanded state when positioned outside the suction catheter; The second state is tightened and unfolded. In the thrombectomy device of this embodiment, the filter assembly is contracted and movably placed inside the suction catheter. When in use, the filter assembly can stretch out parallel to the distal end of the suction catheter and expand, and the filter screen can be expanded as it expands. Effectively collect the fallen thrombus to prevent the thrombus from escaping and improve the collection effect. Since the filter assembly is located at the side of the suction catheter, it will not occupy the effective suction section of the suction port and will not interfere with the inclined suction port. Cause occlusion, can further ensure the suction effect.

The suction catheter 10 of the present embodiment is a composite pipe provided with a multi-layer structure, which is generally arranged as a three-layer structure. From the inside to the outside, there are PTFE (polytetrafluoroethylene) lining layer, S304 steel spring layer or braided layer, And Pebax (polyether block polyamide) or nylon layer, or from inside to outside sequentially PTFE tube, Pebax tube, nylon tube or TUP (thermoplastic polyurethane elastomer rubber) tube, or a tube mixed with multiple materials, the above types The composite tube has good support performance and flexibility, which facilitates the delivery and bending of the suction catheter 10 in the blood vessel.

3, 4 and 5, the suction catheter 10 of this embodiment is provided with a suction chamber 11, a push chamber 12 and a guide wire chamber 13 along the axial direction, the suction chamber 11, the push chamber 12 and the guide wire cavity 13 are arranged side by side. The distal end of the suction catheter 10 is provided with an extension end protruding from the distal end surface of the suction catheter 10, and the extension end can be used to guide the delivery of the catheter 10 in the blood vessel, and the distal ends of the guide wire lumen 13 and the push lumen 12 respectively penetrate The distal end face of the protruding end. The protruding end has a certain taper, made of TPU or Pebax material, with a hardness between 30D and 55D, and has a certain degree of flexibility to prevent the protruding end from causing damage to the vessel wall during movement. The guide wire can protrude to the outside of the aspiration catheter 10 through the distal end surface of the extension end, so as to guide the aspiration catheter 10 to move in the blood vessel. In this embodiment, the distal end surface of the push cavity 12 is flush with the distal end surface of the extension end, that is, it is set beyond the distal end surface of the suction cavity 11. In other embodiments of the present application, the extension end can also be cancelled. structure, so that the distal end surface of the push chamber 12 is flush with the distal end surface of the suction chamber 11.

1, FIG. 3 and FIG. 7, the filter assembly 20 of this embodiment includes a delivery tube 21 and a filter screen 22, the delivery tube 21 is accommodated in the suction catheter 10 and can be along the axial direction of the suction catheter 10 The direction moves and its distal end can protrude from the end of the suction catheter 10 . The distal end of the delivery tube 21 has a first contracted state when inside the aspiration catheter 10 and a second expanded state when outside the aspiration catheter 10 . The filter screen 22 is connected to the far end of the delivery pipe 21, so that the filter screen 22 is tightened with the first state of the delivery pipe 21, and unfolded with the second state. The distal end of the nozzle is provided with a nozzle hole 21121 that communicates with the nozzle channel 21111.

Specifically, the filter screen 22 of the present embodiment has a tapered structure as a whole when it is unfolded. One end of the filter screen 22 is connected to the distal end of the delivery tube 21 and has an opening. The opening is arranged toward the distal end of the suction catheter 10. The filter screen The radial dimension of the other end of 22 gradually decreases and finally forms a closed structure, thrombus in the blood vessel can enter into the conical structure of the filter screen 22 through the opening and be collected. Wherein, the filter screen 22 is located downstream, and expands with the expansion of the filter assembly. The expanded filter screen 22 can effectively collect the shed thrombus, prevent the thrombus from escaping, and improve the collection effect. Specifically, the filter screen 22 of this embodiment is a soft wire material, such as a braided wire made of nickel-titanium wire, PTFE wire, nylon or fiber wire. The delivery tube 21 of this embodiment includes a tubular body part 212 and an annular part 211 in a ring structure in the second state, and the annular part 211 is connected to the distal end of the tubular body part 212 . The annular part 211 includes a ring pipe 2111 and an injection pipe 2112 connected to the ring pipe 2111. The injection pipe 2112 is arranged in the ring structure surrounded by the ring pipe 2111, and its two ends are respectively connected with the injection channel 21111 inside the ring pipe 2111. Specifically, the injection pipe 2112 is one of PTFE pipe, PEbax pipe or TUP pipe, with a hardness of 30-50D. The injection pipe 2112 has too high hardness and is not easy to shrink, and if the hardness is too low, the injection hole 21121 will not be able to withstand the high pressure and rupture when the high-pressure liquid is injected. The ring pipe 2111 is one of PTFE pipe, PEbax pipe, or TUP pipe, with a hardness of 30-50D. If the hardness of the ring tube is too high, it is not easy to shrink; if the hardness is too low, the strength is not enough, and it may break during the release and retraction process. The delivery tube 212 is one or more mixtures of nylon, Pebax, and TUP materials. The hardness is 63-80D. The delivery tube 212 needs to be able to push and retract. The hardness is higher than that of the injection tube 2112, but too high will cause the entire The flexibility of the suction catheter 10 becomes poor, so that the resistance will be too large when pushing and cornering, which will affect the use

Specifically, the proximal end of the filter screen 22 is connected to the ring pipe 2111 , and the spray pipe 2112 is provided with a spray hole 21121 disposed toward the suction catheter 10 . When the distal end of the delivery tube 21 is in the expanded second state, the spray tube 2112 is opposite to the distal end of the suction catheter 10 , and the liquid is sprayed to the distal end of the suction catheter 10 through the spray hole 21121 . The thrombus located between the distal end of the suction catheter 10 and the annular portion 211 begins to decompose under the impact of the ejected liquid and break away from the blood vessel wall, and finally flows to the inside of the filter 22 along with the blood flow, and is collected by the filter 22 to prevent thrombus escape. At the same time, since the jetting direction of the dry nozzle hole 21121 in this embodiment is set toward the distal end of the suction catheter 10 instead of towards the blood vessel wall, it can effectively reduce the damage caused by the liquid to the blood vessel wall during the jetting process, Further reduce the damage to the patient. The injection direction of the nozzle hole 21121 can be at any angle with the distal end surface of the suction catheter 10. Preferably, the injection direction of the injection tube 2112 can be arranged perpendicular to the distal end surface of the suction catheter 10, thereby slowing down the pressure on the patient to the greatest extent. damage caused. Wherein, the liquid ejected from the middle injection tube 2112 of this embodiment may be a medicinal liquid capable of dissolving thrombus. After the medicinal liquid is sprayed out, it can directly impact the large thrombus at the suction port of the suction catheter to rupture the thrombus. It can also flow in the blood vessel to soften the sub-thrombus or old thrombus adsorbed on the blood vessel wall, which helps the thrombus to fall off from the blood vessel wall, and further improves the suction and collection effect.

In other embodiments of the present application, spray holes 21121 can also be provided on both the spray pipe 2112 and the ring pipe 2111, or the spray pipe 2112 and the spray holes 21121 on it can be canceled, and only the ring pipe 2111 is provided with a The nozzle hole 21121 on the distal end surface of the catheter 10.

As shown in FIG. 3 and FIG. 7 , the filter assembly 20 of this embodiment further includes a drawing wire 23 , one end of the drawing wire 23 is arranged inside the annular portion 211 , and the other end of the drawing wire 23 passes through to the proximal end of the suction catheter 10 external. By operating the drawing wire 23 at the proximal end, the tightening of the drawing wire 23 can drive the annular portion 211 to shrink and deform, thereby facilitating the installation of the annular portion 211 inside the suction catheter 10 for delivery. When the annular part 211 protrudes to the outside of the suction catheter 10, the drawing wire 23 is released, so that the drawing wire 23 is in a relaxed state, and the annular part 211 returns to the expanded state under the action of its own elastic deformation, and drives the filter screen 22 to expand, and the The filter screen 22 collects the dropped thrombus. Specifically, the drawing wire 23 of this embodiment is a memory alloy (TiNi, TiNiFe, TiNiCr, CuNi), and the distal end of the drawing wire 23 is welded or bonded to the joint between the annular part 211 and the tubular main part 212 .

Specifically, as shown in FIG. 7 , a part of the injection channel 21111 and a part of the wire drawing channel 21112 are arranged inside the ring pipe 2111 of this embodiment, and the part of the wire drawing channel 21112 is arranged outside the part of the injection channel 21111 along the radial direction. The distal ring of the wire 23 is arranged in the drawing channel 21112, and the proximal end of the drawing wire 23 passes out to the outside of the proximal end of the suction catheter 10, thereby facilitating operation. In this embodiment, in order to prevent the existence of the drawing wire 23 from blocking the flow of the liquid in the spraying channel 21111 , a part of the spraying channel 21111 and a part of the drawing channel 21112 are provided in the ring pipe 2111 . In other embodiments of the present application, the wire drawing channel 21112 can also be arranged on the distal side of the injection channel 21111 in the axial direction, which can also prevent the wire drawing 23 from blocking the flow of the liquid, and effectively prevent the wire drawing channel 21112 from being blocked by the liquid. Blockage in spray path. In other embodiments of the present application, the drawing wire 23 can also be arranged in the injection channel 21111 , that is, only the injection channel 21111 is provided in the ring pipe, and the distal ring of the drawing wire 23 is arranged in the injection channel 21111 .

Furthermore, as shown in FIG. 4 and FIG. 5 , in order to ensure the smooth delivery of the drawing wire 23 during the delivery process, especially to prevent the drawing wire 23 from twisting and deforming when it protrudes to the outside of the suction catheter 10 , the inside of the delivery tube 21 of this embodiment Another part of wire drawing channel 21112 is also provided. Specifically, the tubular main body 212 of this embodiment includes an inner tube 2121 and an outer tube 2122 sheathed on the outside of the inner tube 2121. Another part of the injection channel 21111 is formed inside the inner tube 2121. Between the inner tube 2121 and the outer tube 2122 Another part of the wire drawing channel 21112 is formed. When the distal end of the delivery tube 21 protrudes to the outside of the suction catheter 10, the drawing wire 23 is always in the drawing channel 21112 of the delivery tube 21, and will not be twisted and deformed in the blood vessel, thereby ensuring that the blood normal flow and effective collection of thrombus.

In this embodiment, only the part of the inner tube 2121 close to the distal end is sheathed with the outer tube 2122 , so as to prevent the drawing wire 23 from being twisted and deformed after extending out of the suction catheter 10 . In other embodiments of the present application, all the delivery tube 21 from the proximal end to the distal end can be configured as a combination of the inner tube 2121 and the outer tube 2122 , so as to further effectively ensure the running track of the drawing wire 23 .

Further, as shown in FIG. 1 and FIG. 6 , the thrombectomy device 1 of this embodiment also includes a suction catheter base 30 , and the suction catheter base 30 includes a base body 31 and a first An adjustment knob 32 and a second adjustment knob 33 . The first adjustment knob 32 is connected with the delivery tube 21, and the delivery tube 21 is driven to move along the axial direction of the suction catheter 10 by turning the first adjustment knob 32, so that the distal end of the delivery tube 21 is extended or retracted to the suction catheter 10 Inside. The second adjusting knob 33 is connected with the drawing wire 23, and by turning the second adjusting knob 33, it is used to drive the drawing wire 23 to move along the axial direction of the suction catheter 10, so as to tighten or expand the ring pipe 2111, and then filter the filter screen 22 Shrink and expand. The seat body 31 is also provided with a suction joint 311, an injection liquid joint 312 and a guide wire joint 313, wherein one end of the suction joint 311 communicates with the suction chamber 11, and the other end of the suction joint 311 can be connected to the negative pressure generator. The suction cavity 11 is kept in a negative pressure state through the negative pressure generator, and then the thrombus in the blood vessel is extracted. One end of the injection fluid connector 312 communicates with the injection channel 21111 of the delivery tube 21 , and the other end can be connected with an infusion pump, which provides high-pressure or low-pressure liquid into the injection channel 21111 .

Further, the distal end of the suction catheter 10 in this embodiment is also provided with a developing member 40, specifically a developing ring, which is made of a material containing platinum or tantalum that has a developing effect. Specifically, the developing ring in this embodiment is located close to the opening of the distal end of the suction catheter 10 , so as to facilitate confirmation of the distal end position of the suction catheter 10 .

Further, the distal end of the suction catheter 10 in this embodiment has a wedge-shaped structure, and the wedge angle of the wedge-shaped structure ranges from 10° to 40°. The suction force is equal to the product of the pressure and the area of the suction port. Compared with the circular port, the wedge-shaped port can provide greater suction force, and the wedge-shaped port does not exceed 40°, so that the thrombectomy device 1 has better suction force. The wedge angle is greater than 10°, which facilitates the preparation of the wedge-shaped structure at the distal end of the suction catheter 10 .

When the thrombectomy device 1 of this embodiment is used for intravascular thrombectomy, a guide wire is first used to establish a passage in the blood vessel, and the distal opening of the suction catheter 10 of the thrombectomy device 1 is moved along the guide wire in the state shown in Figure 1. Move to the upstream of the thrombus lesion position; then turn the first adjustment knob 32, so that the distal end of the delivery tube 21 stretches out to the outside of the suction catheter 10 and has a certain distance from the distal end of the suction catheter 10, so that the filter screen 22 is placed in the downstream of the thrombus; then turn the second adjustment knob 33 to make the drawing wire 23 in a relaxed state and automatically expand the ring pipe 2111, the filter screen 22 expands with the expansion of the ring pipe 2111, and the opening of the filter screen 22 is relatively drawn The distal end of the suction catheter 10 is provided. Then turn on the negative pressure generator to suck the thrombus in the blood vessel, and at the same time turn on the infusion pump to let the injection tube 2112 spray low-pressure medicinal liquid to soften the thrombus (mostly used for old or firmer thrombus), so that the thrombus can be separated from the blood vessel wall and Easy to pump. When a large thrombus blocks the suction cavity 11, by turning the first adjustment knob 32, the annular portion 211 is moved toward the direction of the suction catheter 10, so that the jet tube 2112 reaches the vicinity of the distal suction port of the suction catheter 10, Then the high-pressure liquid is sprayed through the injection tube 2112 to impact the large thrombus and fragment the large thrombus, so that the fragmented thrombus is sucked into the suction chamber 11 inside the suction catheter 10, and finally the suction is completed. Afterwards, the suction catheter 10 is withdrawn from the body. In the process of withdrawing from the body, first turn the second adjustment knob 33 to tighten the wire drawing 23 and drive the ring portion 211 to shrink and deform, and then turn the first adjustment knob 32 to shrink the ring portion 211 of the deformation port and the filter screen. 22 is retracted together with the delivery tube 21 into the push cavity 12, and finally the filter assembly 20 and the suction catheter 10 are withdrawn from the body together to prevent the filter assembly 20 outside the suction catheter 10 from damaging the blood vessel wall in the process of withdrawing from the body. cause scratches.

Implementation mode two

Based on the above-mentioned thrombectomy device, this embodiment exemplarily provides another specific implementation manner of the thrombectomy device. As shown in FIG. 8 and FIG. 9 , the thrombus removal device 1 in this embodiment is generally consistent with that in Embodiment 1, including a suction catheter 10 , a filter assembly 20 , a support seat 30 and a developing member 40 , and the filter assembly 20 The structure of the distal end is consistent with the structure of the distal end in Embodiment 1. Different from the suction catheter 10 in Embodiment 1 which has a three-lumen structure with a suction lumen 11, a push lumen 12 and a guide wire lumen 13, the suction catheter 10 in this embodiment has a suction lumen 11 and a guide wire lumen 13 double lumen structure. Wherein, the delivery tube 21 and the drawing wire 23 are both arranged in the suction chamber 11, and can move along the axial direction of the suction cavity 11, so that during the suction process of the thrombus, the filter screen 22 at the far end of the delivery tube 21 can be Withdrew into the suction chamber 11 of the suction catheter 10 in the unfolded state, and sprayed liquid on the large thrombus in the suction chamber 11 through the injection tube 2112, increasing the impact force on the thrombus, thereby effectively The thrombus in 11 is crushed and dissolved, thereby further ensuring the suction process of the thrombus, and further preventing the thrombus from escaping.

Implementation Mode Three

Based on the above thrombectomy device, this embodiment exemplarily provides another specific implementation manner of the thrombus retrieval device. As shown in FIG. 10 , FIG. 11 and FIG. 12 , the thrombectomy device 1 in this embodiment is generally consistent with that in Embodiment 1, including a suction catheter 10 , a filter assembly 20 , a support seat 30 and a developing member 40 , and The structure of the distal end of the filter assembly 20 is consistent with the structure of the distal end in the first embodiment. Different from the suction catheter 10 in Embodiment 1 which has a three-lumen structure of a suction lumen 11, a push lumen 12 and a guide wire lumen 13, the part of the suction catheter 10 in this embodiment near the proximal end has a suction lumen 11 1. The three-lumen structure of the push chamber 12 and the guide wire chamber 13, the part near the far end is a double-lumen structure with the suction chamber 11 and the guide wire chamber 13, that is, the distal end face of the push chamber 12 is larger than the suction chamber 11. The distal end face of the suction catheter 10 is disposed near the proximal end. The proximal ends of the delivery tube 21 and the drawing wire 23 are both arranged in the push cavity 12 and arranged side by side, so as to ensure the smooth delivery of the delivery tube 21 and the drawing wire 23 in the suction catheter 10 . The distal ends of the delivery tube 21 and the drawing wire 23 are both arranged in the suction chamber 11 and arranged side by side, so that during the aspiration process of the thrombus, the filter 22 at the distal end of the delivery tube 21 can be withdrawn to the suction chamber in an unfolded state. into the suction chamber 11 of the catheter 10, and spray liquid on the large thrombus in the suction chamber 11 through the spray tube 2112, increasing the impact on the thrombus, and effectively crushing and dissolving the thrombus in the suction chamber 11 , so as to further ensure the suction process of the thrombus, and further prevent the thrombus from escaping.

The above is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed in the present invention can easily think of changes or Replacement should be covered within the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.

Claims (12)

1. A thrombolytic device, comprising:

a suction catheter for sucking thrombus;

a filter assembly disposed within the aspiration catheter and movable in a direction parallel to the axial direction of the aspiration catheter, a distal end of the filter assembly extending beyond the distal end of the aspiration catheter during axial movement of the filter assembly;

the filter assembly comprises a conveying pipe and a filter screen; the delivery Guan Rong is disposed within the aspiration catheter and is movable in an axial direction parallel to the aspiration catheter and the delivery tube distal end is extendable beyond the aspiration catheter distal end; the distal end of the delivery tube having a first state that contracts when positioned within the aspiration catheter and a second state that expands when positioned outside the aspiration catheter; the screen is attached to the distal end of the delivery tube such that the screen tightens and deploys with the first and second conditions of the delivery tube.

2. The thrombectomy device of claim 1, wherein the delivery tube has an injection passage therein and a distal end of the delivery tube has an orifice therethrough, the orifice being opposite the aspiration port of the aspiration catheter in the second state.

3. The thrombus removal device of claim 2, wherein the distal end of the delivery tube is provided with an annular portion, a portion of the injection passage is provided in an inner annulus of the annular portion, and the annular portion is provided with the injection hole penetrating the injection passage.

4. A thrombus removal device as in claim 3 wherein the annular portion comprises a collar and at least one jet tube, the proximal end of the screen is connected to the collar, the distal end of the screen is spaced from the distal end of the delivery tube, the two ends of the jet tube are connected to the collar respectively, and the jet tube and/or the collar are provided with the jet holes.

5. The thrombectomy device of claim 3, wherein the filter assembly further comprises a wiredrawing having one end looped inside the annular portion and the other end of the wiredrawing extending outside the aspiration conduit.

6. The thrombectomy device of claim 5, wherein a portion of the wiredrawing channel is further disposed around the inside of the annular portion, the portion of the wiredrawing channel is disposed radially outside the injection channel or the portion of the wiredrawing channel is disposed axially on the distal side of the injection channel, and one end of the wiredrawing is disposed around the inside of the portion of the wiredrawing channel.

7. The thrombectomy device of claim 6, wherein the aspiration catheter has an aspiration lumen disposed therein in an axial direction, and wherein the wiredrawing and the delivery tube are disposed in a side-by-side relationship with the aspiration lumen.

8. The thrombectomy device of claim 6, wherein the suction catheter is internally provided with a suction lumen and a pushing lumen in an axial direction, the suction lumen and the pushing lumen are disposed side by side, and the wiredrawing and the delivery tube are disposed together in the pushing lumen.

9. The thrombectomy device of claim 8, wherein the delivery tube further comprises a tubular body portion, a distal end of the tubular body portion being connected to the annular portion, the tubular body portion comprising an inner tube and an outer tube disposed about the inner tube, the inner tube defining a further portion of the injection passage and a further portion of the wiredrawing passage therebetween.

10. The thrombectomy device of claim 8, wherein the distal end face of the push lumen is flush with the distal end face of the aspiration lumen, or the distal end face of the push lumen is disposed closer to the proximal end of the aspiration catheter than the distal end face of the aspiration lumen, or the distal end face of the push lumen is disposed farther from the proximal end of the aspiration catheter than the distal end face of the aspiration lumen.

11. The thrombectomy device of claim 5, further comprising a suction catheter hub having a rotatable first adjustment knob and a second adjustment knob disposed thereon, the first adjustment knob coupled to the delivery tube for driving the delivery tube in an axial direction of the suction catheter, the second adjustment knob coupled to the wiredrawing for driving the wiredrawing in an axial direction of the suction catheter.

12. The thrombectomy device of any one of claims 1-11, wherein the distal suction port of the aspiration catheter has a wedge-shaped configuration inclined relative to its axis, the wedge-shaped configuration having a wedge angle in the range of 10 ° to 40 °.

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