CN116125679A - Personalized defocus parameter determining method, lens matching method and effect evaluation equipment - Google Patents

Abstract

An embodiment of the present invention provides a method for determining a personalized defocus parameter, a method for dispensing glasses, and an effect evaluation device. The method for determining a personalized defocus parameter includes: obtaining a baseline parameter of a myopia patient; determining the myopia patient according to the baseline parameter Corresponding personalized defocus parameters, the personalized defocus parameters include: personalized lens rear surface optical zone BOZD and/or personalized relative corneal refractive power RCRP. This method can provide personalized defocus design for different groups of people to obtain better myopia control effect.

Description

A method for determining individualized defocus parameters, a method for dispensing glasses, and an effect evaluation device

technical field

The invention relates to the field of optical myopia prevention and control, in particular to a method for determining a personalized defocus parameter, a method for distributing glasses and an effect evaluation device.

Background technique

Myopia is one of the most common eye diseases worldwide, mostly affecting children and adolescents. It is estimated that by 2050, the prevalence of myopia will increase to 49.8% of the global population. Myopia is due to the interaction of genetic and environmental factors, resulting in excessive axial growth of the eye. Premature occurrence and rapid growth of myopia can lead to a sharp increase in the number of patients with high myopia, which eventually increases the risk of complications such as myopic macular degeneration, retinal detachment and glaucoma, and even blindness in severe cases. Prevention and control of myopia is urgent.

The mechanism of the development of myopia is still unclear, and the commonly used clinical methods for the prevention and control of myopia include different concentrations of drugs and different optical defocus design lenses. The peripheral defocus theory proposed by Professor Smith of the School of Optometry at the University of Houston in the United States at the end of the last century is currently generally accepted as the cause of myopia. Peripheral defocus theory holds that this hyperopic defocus around the retina is the main reason for the continuous increase in the degree of myopia. The myopic defocus around the retina can slow down the growth of the eye axis and have the effect of inhibiting the development of myopia. Compared with traditional glasses treatment, various types of myopia defocused lenses can delay the growth of eye axis by 32%-63%.

Although the underlying mechanism by which myopic defocus delays myopia progression is not fully understood, changes in the relative peripheral defocus (relative peripheral defocus) and higher order aberrations (HOA, high order aberration) in the defocus design are thought to affect myopia control. main factor of the effect. Relative corneal refractive power (RCRP) can be used to indicate the degree of myopic defocus caused on the peripheral retina. Recent studies have shown that the amount or distribution of RCRP is closely related to delaying the development of myopia. The amount and distribution of RCRP also affect higher-order aberrations, including total higher-order aberration HOA, spherical aberration (SA) and coma (COMA). It has been confirmed that the increase of total HOA is significantly related to the delay of eye axis and the control of myopia.

In the process of realizing the present invention, the inventors found that there are at least the following problems in the prior art: the myopia defocus design of the existing products on the market is mostly a standardized design, which is not conducive to the personalized prevention and control of myopia patients.

Contents of the invention

In view of this, the purpose of the embodiments of the present invention is to provide a method for determining a personalized defocus parameter, a method for distributing glasses, and an effect evaluation device, so as to facilitate the personalized prevention and control of myopia patients.

In order to achieve the above purpose, in the first aspect, an embodiment of the present invention provides a method for determining a personalized defocus parameter, which includes:

Obtain baseline parameters of myopia patients;

The personalized defocus parameters corresponding to the myopia patient are determined according to the baseline parameters, and the personalized defocus parameters include: personalized lens rear surface optical zone BOZD and/or personalized relative corneal refractive power RCRP.

In some possible implementation manners, the baseline parameters include one or more of the following: age, degree of myopia, pupil radius, and axial length of the eye.

In some possible implementation manners, determining the personalized RCRP corresponding to the myopia patient according to the baseline parameters specifically includes:

According to the baseline parameters and the preset defocus curve equation, determine the personalized RCRP corresponding to the myopia patient; wherein, the preset defocus curve equation represents the relationship between the average amount of RCRP and the baseline parameter Functional relationship.

In some possible implementations, the preset defocus curve equation includes a multi-order curve equation indicating the functional relationship between the average energy of RCRP and the pupil radius.

In some possible implementation manners, the multi-order curve equation includes a fourth-order curve equation.

In some possible implementations, the fourth-order curve equation is as follows:

Y＝(N*(A*X ⁴ -B*X ³ +C*X ² -D*X))+M;

Among them, A, B, C, D, M, and N are constants, Y is the average energy of RCRP, and X is the pupil radius.

In some possible implementation manners, the method also includes:

A plurality of the constants are determined according to the age and axial length of the myopic patient.

In some possible implementation manners, determining the personalized BOZD corresponding to the myopia patient according to the baseline parameters specifically includes:

According to the pupil radius of the myopia patient and the correspondence between the preset pupil radius and BOZD, the personalized BOZD corresponding to the myopia patient is determined.

In some possible implementations, the determination of the personalized BOZD corresponding to the myopia patient according to the pupil radius of the myopia patient and the preset correspondence between the pupil radius and BOZD includes:

When the pupil radius is greater than 2.5mm, it is determined that the personalized BOZD corresponding to the myopia patient is in (3.1, 3.2mm];

When the pupil radius is at (2.3, 2.5] mm, it is determined that the personalized BOZD corresponding to the myopia patient is at (2.9, 3.1] mm;

When the pupil radius is at (2, 2.3] mm, it is determined that the personalized BOZD corresponding to the myopia patient is at (2.8, 2.9] mm;

When the pupil radius is less than 2 mm, it is determined that the personalized BOZD corresponding to the myopia patient is at [2.6, 2.8] mm.

In some possible implementation manners, obtaining the pupil radius of the myopia patient specifically includes:

Obtain the pupil radius of the myopia patient from a special pupillometer or an ophthalmic detector with pupillometer function.

In a second aspect, a method for dispensing glasses is provided, the method comprising:

Determining the individualized defocus parameters of the myopia according to any one of the methods described in the first aspect;

Configuring glasses for the myopia patient according to the personalized defocus parameter.

In some possible implementation manners, the glasses include any one or more of the following: defocused soft lenses, defocused frame glasses, defocused scleral lenses, defocused RGP, and orthokeratology lenses.

In a third aspect, a myopia control effect evaluation device is provided, including a memory, a processor, and a computer program stored on the memory and operable on the processor, and the processor implements the following when executing the computer program deal with:

According to any one of the individualized defocus parameter determination methods described in the first aspect, determine the individualized defocus parameter of the myopia patient;

Obtaining the axial growth of the myopia patient after wearing glasses based on the personalized defocus parameter for a preset period of time;

The myopia control effect of the glasses on the myopia patient is determined according to the eye axial growth amount.

In some possible implementation manners, the determining the myopia control effect of the glasses on the myopia patient according to the eye axis growth amount specifically includes:

When the axial growth of the eye is less than 0.2 mm, it is determined that the myopia control effect is good;

When the axial growth of the eye is in the range of 0.2mm-0.3mm, it is determined to achieve the average myopia control effect;

When the axial growth of the eye is greater than 0.3 mm, it is determined that the myopia control effect is poor.

In a fourth aspect, a computer-readable storage medium is provided, on which a computer program is stored, and when the computer program is executed by a processor, any one of the methods described in the first aspect and the second aspect is implemented.

In a fifth aspect, a computer device is provided, which includes:

one or more processors;

storage means for storing one or more programs;

When the one or more programs are executed by the one or more processors, the one or more processors are made to implement any one of the methods described in the first aspect and the second aspect.

The above technical scheme has the following beneficial effects:

In the embodiment of the present invention, the baseline parameters of the myopia are obtained; according to the baseline parameters, the personalized defocus parameters corresponding to the myopia are determined, and the personalized defocus parameters include: personalized lens rear surface optical zone BOZD and/or Personalized relative corneal refractive power RCRP; thus, the personalized design of defocus distribution in the embodiment of the present invention can improve the effective rate of clinical myopia prevention and control.

Description of drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. Obviously, the accompanying drawings in the following description are only These are some embodiments of the present invention. Those skilled in the art can also obtain other drawings based on these drawings without creative work.

FIG. 1 is an overall flowchart of a method for determining a personalized defocus parameter according to an embodiment of the present invention;

FIG. 2A is a specific flowchart of a method for determining a personalized defocus parameter according to an embodiment of the present invention;

FIG. 2B is a graph corresponding to adjusting different constants M and N according to an embodiment of the present invention;

Fig. 3A is a comparison diagram of the treatment area radii of two groups of BOZD plastic mirrors according to the embodiment of the present invention;

Fig. 3B is a comparison chart of eccentricity values of two groups of BOZD shaping mirrors according to the embodiment of the present invention;

Fig. 4 is a schematic diagram of the relationship between the growth of the eye axis and the follow-up time of the two groups of BOZD plastic lenses according to the embodiment of the present invention;

Fig. 5A is a schematic diagram of the effect comparison of the total defocus and shape difference within the range of the average pupil radius of 4.8 mm of the two groups of BOZD shaping mirrors in the embodiment of the present invention;

Fig. 5B is a schematic diagram of the effect comparison of the total amount and shape difference of RCRP produced by the relative corneal refractive power Y of the two groups of BOZD shaping lenses in the embodiment of the present invention;

Figure 5C is a schematic diagram of the effect comparison of the distance X from the pupil center point and the shape difference of the two groups of BOZD shaping mirrors in the embodiment of the present invention;

Fig. 6 is a schematic diagram of the relationship curve comparison between the value x and the average RCRP of the distance from the center of the cornea of two groups of BOZD shaping lenses according to the embodiment of the present invention;

Fig. 7 is a schematic flow chart of a method for dispensing glasses according to an embodiment of the present invention;

FIG. 8 is a functional block diagram of a computer-readable storage medium according to an embodiment of the present invention;

FIG. 9 is a functional block diagram of a computer device according to an embodiment of the present invention.

Detailed ways

The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

Existing optical myopia prevention and control products (such as defocusing soft lenses, defocusing frame glasses, orthokeratology lenses, etc.) do not take into account the differences in individual baseline parameters (baseline Parameters such as age, degree of myopia, pupil size, axial length of the eye, etc.), did not take into account the different defocus size and defocus position design may achieve the myopia prevention and control effect is very different. In short, the myopia defocus design of the existing products on the market is mostly a standardized design, which is not conducive to the personalized prevention and control of myopia patients. The personalized defocus distribution design of the embodiment of the present invention can improve the effective rate of clinical myopia prevention and control.

Therefore, an object of the embodiments of the present invention is to provide personalized defocus design for different groups of people, so as to obtain better myopia control effect. In this embodiment, the personalization of the defocus lens parameters for myopia prevention and control is aimed at changing RCRP or HOA in combination with pupil parameters, so that myopia patients can achieve better myopia prevention and control. Specifically, the purpose of the embodiments of the present invention is to solve the clinically unrealized myopia prevention and control personalized defocus design, and design the defocus amount according to the patient's age, degree of myopia, axial length and pupil size.

In an embodiment of the present invention, the measurements of RCRP and HOA varied with pupil size. Larger pupils allow more myopia defocus to fall within the pupil rim, producing more relative peripheral myopia defocus and HOA, resulting in better myopia control. Narrowing the back optic zone (BOZD, Back optic zone diameter) of the lens can improve the effect of myopia control, but the effect of changing BOZD on RCRP and corneal HOA has rarely been studied, and the results of evaluating the distribution of RCRP within the pupil radius will be beneficial to myopia Evaluation of the correlation between the defocus distribution of prevention and control and the improvement of myopia prevention and control efficiency.

The technical solution of the embodiment of the present invention is applicable to all myopia prevention and control products based on defocus design, including but not limited to orthokeratology lens, defocus (Rigid Gas Permeable Contact Lens, RGP), defocus soft lens, defocus scleral lens wait.

Fig. 1 is an overall flowchart of a method for determining a personalized defocus parameter according to an embodiment of the present invention. As shown in Fig. 1, the method includes the following steps:

S110: Obtain baseline parameters of myopia patients.

In some embodiments, the baseline parameters include one or more of: age, degree of myopia, pupil radius, current or initial axial length of the eye.

S120: Determine personalized defocus parameters corresponding to the myopia patient according to the baseline parameters, where the personalized defocus parameters include: personalized lens rear surface optical zone BOZD and/or personalized relative corneal refractive power RCRP.

Fig. 2A is a specific flowchart of a method for determining a personalized defocus parameter according to an embodiment of the present invention. As shown in Fig. 2A, in some embodiments, the personalized RCRP corresponding to the myopia patient is determined according to the baseline parameters, specifically including:

S122: Determine the personalized RCRP corresponding to the myopia patient according to the baseline parameter and the preset defocus curve equation; wherein, the preset defocus curve equation represents a functional relationship between the average energy of RCRP and the baseline parameter.

In some embodiments, the preset defocus curve equation includes a multi-order curve equation indicating the functional relationship between the average energy of RCRP and the pupil radius.

In some embodiments, the multi-order curvilinear equations include fourth-order curvilinear equations. In one example, the fourth-order curve equation can be as follows:

Y＝(N*(A*X ⁴ -B*X ³ +C*X ² -D*X))+M;

Among them, A, B, C, D, M, and N are constants, Y is the average energy of RCRP, and X is the pupil radius.

In some embodiments, the method also includes:

The constant M is determined according to the age and/or the axial length of the myopia; the constant N is determined according to the pupil radius of the myopia.

Specifically, if the pupil of the myopic patient is very large, that is, when it is larger than the standard pupil value, this implementation will appropriately move the curve corresponding to the fourth-order curve equation outward (to the right), which is achieved by adjusting the value of N. When the pupil of the myopic patient is small, that is, smaller than the standard pupil value, this embodiment will appropriately move the curve corresponding to the fourth-order curve equation inward (to the left), which is achieved by adjusting the value of N. By changing the value of N, the curve corresponding to the fourth-order curve equation can be translated left and right. That is, when the pupil of a myopic patient is smaller than the standard pupil value, the curve is translated to the left, so that the curve is as close as possible to the center of the pupil; when the pupil of the myopic patient is larger than the standard pupil value, the curve is translated to the right.

Specifically, the up and down stretching of the curve corresponding to the fourth-order curve equation can be realized by adjusting the M value. For example, for young myopic patients, a larger defocus amount is required, so that the M value is increased a little. Although the shape of the curve remains the same, the position of the curve will be higher.

Age is the most significant factor affecting the development of myopia. Usually, the younger the age, the faster the degree increases. Clinical observation found that when the age is ≤11 years old, the diopter increase is significantly related to the initial axial length of the eye. The growth rate is still very fast, and this group of people needs to improve the design of defocus to achieve better myopia control effect. Pupil size affects the amount of myopia defocus perceived by the human eye. The larger the pupil, the more myopia defocus can be obtained by the fundus. The greater the myopia defocus amount, the slower the degree of increase. In this embodiment, combining pupil size, age and axial length, an innovative personalized RCRP design is proposed to achieve better myopia prevention and control effects.

As shown in FIG. 2B , the value ranges of M and N may be in [0, 2]. In Fig. 2B, M and N corresponding to curve 21 are equal to 0; N corresponding to curve 22 in Fig. 2B is equal to 2, and M is equal to 0; M corresponding to curve 23 is equal to 2, and N is equal to 2. At this time, pupil radius r=1.5 When mm～2mm, RCRP has reached 5D～6D. In the embodiment of the present invention, M and N can be adjusted according to the pupil size, so that people with pupils of different sizes can feel as much defocus as possible.

As shown in Figure 2A, in some embodiments, the personalized BOZD corresponding to the myopia patient is determined according to the baseline parameters, specifically including:

S124: According to the pupil radius of the myopia patient and the correspondence between the preset pupil radius and the BOZD, determine the personalized BOZD corresponding to the myopia patient.

In some embodiments, according to the pupil radius of the myopia patient and the correspondence between the preset pupil radius and BOZD, the personalized BOZD corresponding to the myopia patient is determined, specifically including:

When the pupil radius is greater than 2.5mm, determine that the personalized BOZD corresponding to the myopia patient is in (3.1, 3.2]mm;

When the pupil radius is at [2.3, 2.5] mm, determine that the personalized BOZD corresponding to the myopia patient is at (2.9, 3.1] mm;

When the pupil radius is at [2, 2.3] mm, determine that the personalized BOZD corresponding to the myopia patient is at (2.8, 2.9) mm;

When the pupil radius is less than 2 mm, it is determined that the personalized BOZD corresponding to the myopia patient is at (2.6, 2.8] mm.

In some embodiments, acquiring the pupil radius of the myopia patient specifically includes: acquiring the pupil radius of the myopia patient from a dedicated pupillometer or an ophthalmic detector with a pupillometer function.

Following is the research process of the embodiment of the present invention:

The embodiment of the present invention adopts two kinds of shaping mirrors with BOZD (5mm and 6.2mm) on the rear surface of the lens to study the difference in myopia control between two groups of myopic children with the same baseline, and the relationship between the difference in myopia control and RCRP and HOA. , and analyze the correlation between the RCRP difference (including shape difference and volume energy difference) and myopia control effect within the pupil range of each individual, so as to obtain the best defocus distribution curve equation within the pupil range.

Fig. 3A is a comparison diagram of the treatment area radii of two groups of BOZD plastic mirrors according to the embodiment of the present invention. In FIG. 3A , the vertical axis represents the radius of the treatment area in mm, and the horizontal axis represents the groups, including group A and group B. As shown in Figure 3A, according to the data of myopia patients wearing for one year, the size of the treatment area of the 5mm BOZD in group A is 2.12mm in radius; while the size of the treatment area of the 6.2mm BOZD in group B is 2.62mm; there is a significant difference between the two. Fig. 3B is a comparison chart of eccentricity values of two groups of BOZD shaping mirrors according to the embodiment of the present invention. In Figure 3B, the vertical axis represents the eccentricity value in mm, and the horizontal axis represents the group, including group A and group B. There is no difference in the degree of eccentricity or eccentricity of the lens after wearing the two lenses, which are 0.20 and 0.24, respectively.

Fig. 4 is a schematic diagram of the relationship between the axial growth of the eye and the follow-up time of the two groups of BOZD plastic lenses according to the embodiment of the present invention. In Figure 4, the vertical axis represents the amount of axial growth in millimeters, and the horizontal axis represents the follow-up time in months. As shown in Figure 4, the axial growth of 0.13mm in the 5mm BOZD group was significantly smaller than that in the 6.2mm BOZD group of 0.28mm after wearing for 1 year; it can be seen that the small BOZD is more beneficial to myopia control.

The following is a detailed analysis of the difference in the total amount and morphology of RCRP produced by 5mm BOZD and 6.2mm BOZD.

Figures 5A to 5C are schematic diagrams of the comparison of the total amount and shape of RCRP produced by the distance X from the center of the pupil or the relative corneal refractive power Y of the two groups of BOZD shaping lenses in the embodiment of the present invention. In Figure 5A to Figure 5C, the vertical axis is the sample percentage, and the horizontal axis is the distance X from the center of the pupil or the relative corneal refractive power Y; sum4.8 is the total amount of RCRP within 4.8 mm.

As shown in Figure 5A, analyzing the total amount of defocus within the range of the average pupil radius of 4.8mm, the amount of defocus produced by the 5mm BOZD indicated by the label 51 is significantly greater than the 6.2mm BOZD indicated by the label 52, which shows that within the same pupil range The total amount of defocus RCRP is relatively large, and when it reaches 15.71D*mm ² energy, the control effect will be better than 10.68D*mm ² energy.

As shown in Figure 5B, comparing the difference in X (distance from the pupil center) between the two groups of BOZD at the same Y value (relative corneal refractive power RCRP), it is found that the effect is better when X is smaller. Figure 5B reflects that when the value of Y is the same, the smaller X is, the steeper the curve is, and the better the control effect is.

As shown in Figure 5C, the value of the distance X from the center of the pupil when the same amount of defocus energy is achieved within the pupil range, the 5mm BOZD group is significantly smaller than the 6.2mm BOZD. It can be seen that the steeper distribution of the RCRP defocus curve is more beneficial to delay The development of myopia.

Fig. 6 is a schematic diagram of the relationship curve comparison between the value x from the center of the cornea and the average RCRP of two groups of BOZD shaping lenses according to the embodiment of the present invention. In Figure 6, x represents the value from the center of the cornea, and the larger the x, the farther the distance from the center; the ordinate is the Y value, which represents the average RCRP. As shown in Figure 6, the defocus curve within the pupil range, 5mm BOZD is a curve marked with a dot, starting from the center of the pupil (0 point), the curve marked with a dot reaches around 1mm, and the curve marked with a dot The slope is significantly larger than the 6.2mm BOZD curve marked with a triangle. It can be seen that within the pupil range, the distribution radius of RCRP within the range of 1.2-2.4mm (10°-20° range of the retina) tends to be a curve distribution marked with dots, and the steeper slope is more conducive to myopia control. This curve satisfies the fourth-order curve equation:

Y＝(N*(A*X ⁴ -B*X ³ +C*X ² -D*X))+M;

Among them, A, B, C, D, M, and N are constants, Y is the average energy of RCRP, and X is the pupil radius.

In this embodiment, changing N and M can adjust the shape and position of the RCRP curve according to the size of the pupil, and control the RCRP energy of the entrance pupil.

The value of BOZD is determined according to the type of application. Taking this method applied to the defocused soft mirror as an example, the BOZD and RCRP values are determined according to the pupil size and the preset correspondence (based on some pre-clinical test results):

If the pupil radius X∈[2.3,2.5]mm is measured when the indoor light is 300lx lux, BOZD=(2.9,3.1]mm;

If pupil radius X∈[2,2.3]mm, BOZD∈(2.8,2.9]mm;

If pupil radius X<2mm, BOZD∈(2.6,2.8]mm;

If pupil radius X>2.5mm, BOZD∈(3.1,3.2]mm;

RCRP＝(N*(A*X ⁴ -B*X ³ +C*X ² -D*X))+M;

X is pupil radius; A, B, C, D, M, N are constant coefficients;

Among them, the RCRP value can be adjusted according to the initial age (≤11 years old or >11 years old) and the initial axial length of the eye (≤24.5mm or >24.5mm), the axial length of the eye is less than or equal to 24.5mm, or the age is less than or equal to 11 Older people tend to increase their degrees, so they need to increase the amount of RCRP or reduce BOZD. The amount of RCRP can be changed by changing the coefficients of A, B, C, D, M, and N to make the RCRP curve steeper. Change the values of A, B, C, D, M, and N to achieve the RCRP value in the range of 2.5D to 4.5D. The following examples illustrate:

The patient is 8 years old, the initial axial length is 24.4mm, the degree of myopia is -1.00D, and the pupil radius is 2.6mm. For this patient, the personalized or customized BOZD and RCRP values are determined according to the previous method as follows:

When the pupil radius is greater than 2.5mm, it is determined that the personalized BOZD corresponding to the myopia patient is in (3.1, 3.2]mm; at this time, RCRP=(N*(A*X ⁴ -B*X ³ +C*X ² -D* X))+M; adjust A, B, C, D, M, and N as constants, so that RCRP is in the range of 2.5D-4D.

In a preferred embodiment, the fourth-order curve equation can be:

Y=0.7198*X ⁴ −4.213*X ³ +7.8714*X ² −3.6012*X.

In this embodiment, changing M and N can allow the curve to personalize the RCRP of the entrance pupil according to different pupil sizes, different ages and initial eye axes.

In this example, the changes in the total aberration and third-order aberrations of the 5mm BOZD group and the 6.2mm BOZD group are significantly different. From the perspective of aberration, it can be seen that the 5mm BOZD group has a better myopia control effect.

Fig. 7 is a schematic flowchart of a method for dispensing glasses according to an embodiment of the present invention. As shown in Figure 7, the method of dispensing glasses includes:

S210: Obtain baseline parameters of myopia patients;

S220: Determine the personalized defocus parameters corresponding to the myopia patient according to the baseline parameters, the personalized defocus parameters include: personalized lens rear surface optical zone BOZD and/or personalized relative corneal refractive power RCRP

S230: Configure glasses for the myopia patient according to the personalized defocus parameter.

The shape and distribution of RCRP in this personality mainly considers that people with young age, short eye axis, and small pupils are more likely to develop myopia. The shape of RCRP can be changed to make the RCRP curve closer to the pupil area, so that the pupil can feel more RCRP to achieve Better myopia control effect.

The glasses include any one or more of the following: defocused soft lenses, defocused frame glasses, defocused scleral lenses, defocused RGP, orthokeratology lenses.

The embodiment of the present invention also provides a myopia control effect evaluation device, which, as a computer device for evaluating the myopia control effect, includes a memory, a processor, and a computer program stored on the memory and operable on the processor. When the processor executes the computer program, the following processes are implemented:

Determining the individualized defocus parameter of the myopia patient according to any one of the aforementioned methods for determining the individualized defocus parameter;

Obtaining the axial growth of the myopia patient after wearing glasses based on the personalized defocus parameter for a preset period of time;

The myopia control effect of the glasses on the myopia patient is determined according to the eye axial growth amount.

In some embodiments, the determining the myopia control effect of the glasses on the myopia patient according to the eye axis growth amount specifically includes:

When the axial growth of the eye is less than 0.2 mm, it is determined that the myopia control effect is good;

When the axial growth of the eye is in the range of 0.2mm-0.3mm, it is determined to achieve the average myopia control effect;

When the axial growth of the eye is greater than 0.3 mm, it is determined that the myopia control effect is poor.

Among them, the diameter of the pupil is collected by a special pupil measuring instrument, or some ophthalmic inspection instruments have their own pupil data measurement results, which can be used directly.

Eye axis parameters Ophthalmology usually uses "lenstar or IOLmaster". After wearing glasses, the growth of the eye axis is less than 0.2mm per year, which is determined to be a good control effect. The growth of the eye axis is determined to be 0.2-0.3mm per year. It is determined to be an average control effect. Greater than 0.3mm is determined to be poor control effect.

The image eccentricity is obtained by collecting data through a corneal topography instrument (medmont, tomey, or pentacam), and using the collected data to calculate it using matlab. Matlab is a calculation program based on mathematical calculation formulas.

The value of the aberration is obtained directly by the corneal topography instrument (medmont, tomey, or pentacam), and the instrument will give the value of the parameter.

The main indicator for evaluating the effectiveness of myopia prevention and control is the annual growth of the eye axis, which is collected by the instrument. Clinically, eccentricity or aberrations increase after wearing glasses, which is conducive to the prevention and control of myopia and to delay the growth of eye axis. The embodiment of the present invention regards the pupil as a breakthrough point, redesigns the distribution of lens RCRP, so that people with different pupils can perceive more RCRP, and more RCRP may bring greater aberrations, which can improve the prevention and control of myopia Effect.

In some embodiments, the determining the myopia control effect of the glasses on the myopia patient according to the target parameters specifically includes:

Obtain the initial myopia control rate of the myopia patient;

determining the current myopia control rate of the glasses for the myopia patient according to the target parameters;

According to the current myopia control rate and the initial myopia control rate, a myopia control effect is determined.

For example, the initial myopia control rate is 40%-50% (relative to no control, the amount of eye axis growth can be reduced), and the myopia control rate after improving parameters can be increased to 60%-80%. The interval range is affected by age and initial eye axis. Influenced by length, in myopia prevention and control products, a 60% myopia control rate is already a very good control effect.

The beneficial technical effects of the embodiments of the present invention are:

According to the embodiment of the present invention, one or more of the individual's age, initial eye axis length, and individual pupil size can be personalized to design the shape and energy of the RCRP curve, which is of great significance for the prevention and control of personalized myopia.

In the embodiment of the present invention, a good defocus distribution can be designed according to the size of the pupil and the defocus curve equation of the pupil;

In the embodiment of the present invention, it is possible to judge whether a certain defocus curve design is reasonable and whether it is necessary to improve the defocus distribution to achieve better myopia control according to the defocus curve equation;

The embodiment of the present invention provides an effective way of giving personalized defocus distribution to RCRP, and designs an effective total defocus energy and defocus curve shape according to the pupil, so as to achieve better myopia prevention and control effect.

Those skilled in the art can clearly understand that for the convenience and brevity of description, only the division of the above-mentioned functional units and modules is used for illustration. In practical applications, the above-mentioned functions can be assigned to different functional units, Completion of modules means that the internal structure of the device is divided into different functional units or modules to complete all or part of the functions described above. Each functional unit and module in the embodiment may be integrated into one processing unit, or each unit may exist separately physically, or two or more units may be integrated into one unit, and the above-mentioned integrated units may adopt hardware It can also be implemented in the form of software functional units. In addition, the specific names of the functional units and modules are only for the convenience of distinguishing each other, and are not used to limit the protection scope of the present application. For the specific working processes of the units and modules in the above system, reference may be made to the corresponding processes in the aforementioned method embodiments, and details will not be repeated here.

Fig. 8 is a functional block diagram of a computer-readable storage medium according to an embodiment of the present invention. As shown in Fig. 8, an embodiment of the present invention also provides a computer-readable storage medium, and a computer program is stored in the computer-readable storage medium , when the computer program is executed by the processor, each step of the above-mentioned method for determining the personalized defocus parameter or the method for dispensing glasses is realized.

For example, when the computer program is executed by the processor, the following steps of the method for determining the individualized defocus parameters are realized:

Obtain baseline parameters of myopia patients;

The personalized defocus parameters corresponding to the myopia patient are determined according to the baseline parameters, and the personalized defocus parameters include: personalized lens rear surface optical zone BOZD and/or personalized relative corneal refractive power RCRP.

For example, when the computer program is executed by the processor, the following steps of the method for determining the individualized defocus parameters are realized:

Obtain baseline parameters of myopia patients;

Determine the personalized defocus parameters corresponding to the myopia patient according to the baseline parameters, the personalized defocus parameters include: personalized lens rear surface optical zone BOZD and/or personalized relative corneal refractive power RCRP;

Configuring glasses for the myopia patient according to the personalized defocus parameter.

If the integrated module/unit is realized in the form of a software function unit and sold or used as an independent product, it can be stored in a computer-readable storage medium. Based on this understanding, the present invention realizes all or part of the processes in the methods of the above embodiments, and can also be completed by instructing related hardware through a computer program. The computer program can be stored in a computer-readable storage medium, and the computer When the program is executed by the processor, the steps in the above-mentioned various method embodiments can be realized. Wherein, the computer program includes computer program code, and the computer program code may be in the form of source code, object code, executable file or some intermediate form. The computer-readable medium may include: any entity or device capable of carrying the computer program code, a recording medium, a USB flash drive, a removable hard disk, a magnetic disk, an optical disk, a computer memory, and a read-only memory (ROM, Read-Only Memory) , Random Access Memory (RAM, Random Access Memory), electrical carrier signal, telecommunication signal and software distribution medium, etc. Of course, there are other readable storage media, such as quantum memory, graphene memory and so on. It should be noted that the content contained in the computer-readable medium may be appropriately increased or decreased according to the requirements of legislation and patent practice in the jurisdiction. For example, in some jurisdictions, computer-readable media Excludes electrical carrier signals and telecommunication signals.

FIG. 9 is a functional block diagram of a computer device according to an embodiment of the present invention. The embodiment of the present invention also provides a computer device, as shown in FIG. The mutual communication is accomplished through the communication bus 304 .

Memory 303, for storing computer programs;

The processor 301 is configured to implement each step of the above-mentioned method for determining the personalized defocus parameter or the method for dispensing glasses when executing the program stored in the memory 303 .

The processor 301 can be a general-purpose processor, including a central processing unit (Central Processing Unit, CPU), a network processor (Network Processor, NP), etc.; it can also be a digital signal processor (Digital Signal Processing, DSP), an application-specific integrated circuit ( Application Specific Integrated Circuit, ASIC), Field-Programmable Gate Array (Field-Programmable Gate Array, FPGA) or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components.

Memory 303 may include mass storage for data or instructions. By way of example and not limitation, the memory 303 may include a hard disk drive (Hard Disk Drive, HDD), a floppy disk drive, a flash memory, an optical disk, a magneto-optical disk, a magnetic tape, or a Universal Serial Bus (Universal Serial Bus, USB) drive or two or more Combinations of multiple of the above. Storage 303 may include removable or non-removable (or fixed) media, where appropriate. In a particular embodiment, memory 303 is a non-volatile solid-state memory. In particular embodiments, memory 303 includes read-only memory (ROM). Where appropriate, the ROM may be mask programmed ROM, programmable ROM (PROM), erasable PROM (EPROM), electrically erasable PROM (EEPROM), electrically rewritable ROM (EAROM), or flash memory or A combination of two or more of the above.

The communication bus 304 includes hardware, software, or both, for coupling the aforementioned components to each other. For example, a bus may include Accelerated Graphics Port (AGP) or other graphics bus, Enhanced Industry Standard Architecture (EISA) bus, Front Side Bus (FSB), HyperTransport (HT) interconnect, Industry Standard Architecture (ISA) bus, Infinity Wideband Interconnect, Low Pin Count (LPC) Bus, Memory Bus, Micro Channel Architecture (MCA) Bus, Peripheral Component Interconnect (PCI) Bus, PCI-Express (PCI-X) Bus, Serial Advanced Technology Attachment (SATA ) bus, Video Electronics Standards Association local (VLB) bus or other suitable bus or a combination of two or more of these. A bus may comprise one or more buses, where appropriate. Although embodiments of the invention describe and illustrate a particular bus, the invention contemplates any suitable bus or interconnect.

The foregoing describes specific embodiments of this specification. Other implementations are within the scope of the following claims. In some cases, the actions or steps recited in the claims can be performed in an order different from that in the embodiments and still achieve desirable results. In addition, the processes depicted in the accompanying figures do not necessarily require the particular order shown, or sequential order, to achieve desirable results. Multitasking and parallel processing are also possible or may be advantageous in certain embodiments.

Although the present application provides method operation steps such as embodiments or flowcharts, more or less operation steps may be included based on routine or non-inventive efforts. The sequence of steps enumerated in the embodiments is only one of the execution sequences of many steps, and does not represent the only execution sequence. When executed by an actual device or client product, the methods shown in the embodiments or drawings may be executed sequentially or in parallel (for example, in a parallel processor or multi-thread processing environment).

The present invention is described with reference to flowchart illustrations and/or block diagrams of methods, apparatus (systems), and computer program products according to embodiments of the invention. It should be understood that each procedure and/or block in the flowchart and/or block diagram, and a combination of procedures and/or blocks in the flowchart and/or block diagram can be realized by computer program instructions. These computer program instructions may be provided to a general purpose computer, special purpose computer, embedded processor, or processor of other programmable data processing equipment to produce a machine such that the instructions executed by the processor of the computer or other programmable data processing equipment produce a An apparatus for realizing the functions specified in one or more procedures of the flowchart and/or one or more blocks of the block diagram.

These computer program instructions may also be stored in a computer-readable memory capable of directing a computer or other programmable data processing apparatus to operate in a specific manner, such that the instructions stored in the computer-readable memory produce an article of manufacture comprising instruction means, the instructions The device realizes the function specified in one or more procedures of the flowchart and/or one or more blocks of the block diagram.

These computer program instructions can also be loaded onto a computer or other programmable data processing device, causing a series of operational steps to be performed on the computer or other programmable device to produce a computer-implemented process, thereby The instructions provide steps for implementing the functions specified in the flow chart or blocks of the flowchart and/or the block or blocks of the block diagrams.

In the present invention, specific examples have been applied to explain the principles and implementation methods of the present invention, and the descriptions of the above examples are only used to help understand the method of the present invention and its core idea; meanwhile, for those of ordinary skill in the art, according to this The idea of the invention will have changes in the specific implementation and scope of application. To sum up, the contents of this specification should not be construed as limiting the present invention.

Claims (16)

1. A method for determining a personalized defocus parameter, comprising:

acquiring baseline parameters of a myopic patient;

determining a personalized defocus parameter corresponding to the myopic patient according to the baseline parameter, wherein the personalized defocus parameter comprises: the posterior optic surface zone BOZD and/or the relative corneal refractive power RCRP are personalized.

2. The method of claim 1, wherein the baseline parameters include one or more of: age, myopic degree, pupil radius, eye axis length.

3. The method according to claim 2, wherein determining the personalized RCRP for the myope based on the baseline parameters, in particular comprises:

determining the personalized RCRP corresponding to the myopic patient according to the baseline parameter and a preset defocus curve equation; wherein the preset defocus equation represents a functional relationship between the average amount of RCRP and the baseline parameter.

4. A method according to claim 3, wherein the predetermined defocus curve equation comprises a multi-order curve equation indicating the function between the average power of RCRP and pupil radius.

5. The method of claim 4, wherein the multi-order curve equation comprises a fourth-order curve equation.

6. The method of claim 5, wherein the fourth-order curve equation is as follows:

Y＝(N*(A*X ⁴ -B*X ³ +C*X ² -D*X))+M；

wherein A, B, C, D, M, N are constants, Y is the average energy of RCRP, and X is the pupil radius.

7. The method as recited in claim 6, further comprising:

determining a constant M according to the age and/or the ocular axis length of the myopic patient;

a constant N is determined based on the pupil radius of the myope.

8. The method according to claim 2, wherein determining the personalized BOZD corresponding to the myope based on the baseline parameter, comprises:

and determining the personalized BOZD corresponding to the myopic patient according to the pupil radius of the myopic patient and the corresponding relation between the preset pupil radius and the BOZD.

9. The method according to claim 8, wherein the determining the personalized BOZD corresponding to the myopic patient according to the pupil radius of the myopic patient and the corresponding relation between the preset pupil radius and the BOZD specifically comprises:

when the pupil radius is larger than 2.5mm, determining that the personalized BOZD corresponding to the myopic patient is at (3.1, 3.2) mm;

when the pupil radius is 2.3,2.5 mm, determining that the personalized BOZD corresponding to the myopic patient is 2.9,3.1 mm;

when the pupil radius is 2,2.3 mm, determining that the personalized BOZD corresponding to the myopic patient is 2.8,2.9 mm;

and when the pupil radius is smaller than 2mm, determining that the personalized BOZD corresponding to the myopic patient is 2.6,2.8 mm.

10. The method according to claim 2, wherein obtaining the pupil radius of the myope, in particular comprises:

pupil radius of myopes is obtained from a dedicated pupil measuring instrument or an ophthalmic detector with pupil measuring function.

11. A method of dispensing lenses, the method comprising:

determining a personalized defocus parameter for a myope according to the method of any one of claims 1-6;

and configuring glasses for the myopic patients according to the personalized defocus parameters.

12. The method of claim 11, wherein the eyewear comprises any one or more of: defocus soft lens, defocus frame lens, defocus scleral lens, defocus RGP, cornea shaping lens.

13. A myopia control effect evaluation apparatus comprising a memory, a processor and a computer program stored on the memory and executable on the processor, characterized in that the processor implements the following processes when executing the computer program:

determining a personalized defocus parameter for a myope according to the method of any one of claims 1-10;

acquiring the eye axis increment of the myopic patient after wearing glasses based on the personalized defocus parameters for a preset time period;

and determining the myopia control effect of the glasses on the myopic patient according to the eye axis increment.

14. The apparatus of claim 13, wherein said determining a myopia control effect of said glasses on said myope based on said eye axis growth comprises:

when the eye axis increment is smaller than 0.2mm, the myopia control effect is good;

determining that an average myopia control effect is achieved when the eye axis growth is between 0.2mm and 0.3 mm;

when the eye axis growth amount is greater than 0.3mm, it is determined that the myopia control effect is poor.

15. A computer readable storage medium, on which a computer program is stored, which computer program, when being executed by a processor, implements the method according to any of claims 1-10.

16. A computer device, comprising:

one or more processors;

a storage means for storing one or more programs;

the one or more programs, when executed by the one or more processors, cause the one or more processors to implement the method of any of claims 1-10.

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