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CN1158658A - 使用表面质粒基因组共振现象检测生物分子间的相互作用的方法 - Google Patents

使用表面质粒基因组共振现象检测生物分子间的相互作用的方法 Download PDF

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Publication number
CN1158658A
CN1158658A CN95195182A CN95195182A CN1158658A CN 1158658 A CN1158658 A CN 1158658A CN 95195182 A CN95195182 A CN 95195182A CN 95195182 A CN95195182 A CN 95195182A CN 1158658 A CN1158658 A CN 1158658A
Authority
CN
China
Prior art keywords
chelating agent
group
peptide
biosensor unit
poly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN95195182A
Other languages
English (en)
Chinese (zh)
Inventor
彼得·斯坦莱恩
沃尔夫冈·佐纳
比安卡·哈伯曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Publication of CN1158658A publication Critical patent/CN1158658A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN95195182A 1994-09-23 1995-09-21 使用表面质粒基因组共振现象检测生物分子间的相互作用的方法 Pending CN1158658A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4433980A DE4433980C2 (de) 1994-09-23 1994-09-23 Verfahren und Biosensorhit zur Untersuchung der Wechselwirkung von Biomolekülen mittels Oberflächen-Plasma-Resonanz
DEP4433980.1 1994-09-23

Publications (1)

Publication Number Publication Date
CN1158658A true CN1158658A (zh) 1997-09-03

Family

ID=6528988

Family Applications (1)

Application Number Title Priority Date Filing Date
CN95195182A Pending CN1158658A (zh) 1994-09-23 1995-09-21 使用表面质粒基因组共振现象检测生物分子间的相互作用的方法

Country Status (12)

Country Link
EP (1) EP0784792A2 (pt)
JP (1) JPH10505910A (pt)
KR (1) KR970706494A (pt)
CN (1) CN1158658A (pt)
AU (1) AU3608995A (pt)
BR (1) BR9509077A (pt)
CA (1) CA2198615A1 (pt)
CO (1) CO4410395A1 (pt)
DE (1) DE4433980C2 (pt)
PL (1) PL319354A1 (pt)
WO (1) WO1996009547A2 (pt)
ZA (1) ZA958024B (pt)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101261226B (zh) * 2007-03-08 2010-12-08 北京宏荣博曼生物科技有限责任公司 一种基于聚乙二醇的表面等离子共振仪芯片
CN114797804A (zh) * 2022-03-29 2022-07-29 翌圣生物科技(上海)股份有限公司 一种具有长连接臂的nta色谱介质及其制备方法

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6130037A (en) * 1996-04-25 2000-10-10 Pence And Mcgill University Biosensor device and method
US6107080A (en) * 1996-04-25 2000-08-22 Mcgill University Biosensor device and method
US6165335A (en) 1996-04-25 2000-12-26 Pence And Mcgill University Biosensor device and method
US5955379A (en) * 1996-04-25 1999-09-21 Mcgill University Biosensor device and method
JP2002507276A (ja) * 1997-04-24 2002-03-05 アメリカン・ホーム・プロダクツ・コーポレーシヨン 核内受容体リガンドの同定及び特性化のための方法
IL141759A0 (en) * 1998-09-03 2002-03-10 Trellis Bioinformatics Inc Multihued labels
AUPP856399A0 (en) * 1999-02-08 1999-03-04 Australian Membrane And Biotechnology Research Institute Improved compounds for protein binding
US6787368B1 (en) 1999-03-02 2004-09-07 Helix Biopharma Corporation Biosensor method for detecting analytes in a liquid
WO2005038442A1 (ja) * 2003-10-16 2005-04-28 Kabushiki Kaisha Nard Kenkyusho 表面プラズモン共鳴の測定方法および該方法に使用される貴金属化合物
US7804592B2 (en) 2003-10-16 2010-09-28 Nard Institute, Ltd. Method for measuring a surface plasmon resonance and noble metal compound used for the same
JP2010197046A (ja) * 2007-05-28 2010-09-09 Tanaka Holdings Kk バイオセンサー
EP2015071A1 (en) 2007-07-13 2009-01-14 FUJIFILM Corporation Carrier, process for producing same, bioreactor, and chip for surface plasmon resonance analysis
KR100953558B1 (ko) 2007-12-12 2010-04-21 한국전자통신연구원 표면 플라즈몬 공명을 이용한 ｐｓ-ｓｐｃｌ 탐색 장치 및방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4569794A (en) * 1984-12-05 1986-02-11 Eli Lilly And Company Process for purifying proteins and compounds useful in such process
CA1304886C (en) * 1986-07-10 1992-07-07 Heinz Dobeli Metal chelate resins
IL85137A (en) * 1987-01-21 1992-02-16 Ares Serono Res & Dev Ltd Method of assaying for a ligand using surface plasmon resonance effect
CA1340522C (en) * 1987-03-10 1999-05-04 Heinz Dobeli Fusion proteins containing neighbouring histidines for improved purification
DE58905660D1 (de) * 1988-04-25 1993-10-28 Hoffmann La Roche Diagnose-Hilfsmittel.
SE462454B (sv) * 1988-11-10 1990-06-25 Pharmacia Ab Maetyta foer anvaendning i biosensorer
US5169936A (en) * 1989-04-14 1992-12-08 Biogen, Inc. Protein purification on immobilized metal affinity resins effected by elution using a weak ligand
EP0485874B1 (de) * 1990-11-14 1995-09-20 F. Hoffmann-La Roche Ag Immunsensorischer Wandler und Verfahren zu seiner Herstellung

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101261226B (zh) * 2007-03-08 2010-12-08 北京宏荣博曼生物科技有限责任公司 一种基于聚乙二醇的表面等离子共振仪芯片
CN114797804A (zh) * 2022-03-29 2022-07-29 翌圣生物科技(上海)股份有限公司 一种具有长连接臂的nta色谱介质及其制备方法
CN114797804B (zh) * 2022-03-29 2023-08-04 翌圣生物科技(上海)股份有限公司 一种具有长连接臂的nta色谱介质及其制备方法

Also Published As

Publication number Publication date
AU3608995A (en) 1996-04-09
CA2198615A1 (en) 1996-03-28
DE4433980C2 (de) 1996-08-22
DE4433980A1 (de) 1996-03-28
JPH10505910A (ja) 1998-06-09
EP0784792A2 (de) 1997-07-23
WO1996009547A3 (de) 1996-05-30
PL319354A1 (en) 1997-08-04
CO4410395A1 (es) 1997-01-09
BR9509077A (pt) 1997-11-25
ZA958024B (en) 1996-03-25
KR970706494A (ko) 1997-11-03
WO1996009547A2 (de) 1996-03-28

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