CN115153810A - A bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation - Google Patents

Abstract

The invention provides a bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation, and relates to the technical field of ablation forceps, comprising: a main body; an outer sleeve, which is arranged at the bottom of the main body; An inner cannula for clamping and ablating tissue in cooperation with an outer cannula; and a clamping component, wherein the clamping component is arranged at the ends of the outer cannula and the inner cannula, and is used for stable clamping of tissues of various sizes. Push the proximal clamp to approach the distal clamp on the outer sleeve through the inner sleeve, and use the clamping component to clamp the tissue that needs to be ablated, so as to improve the stability and uniformity of the ablation treatment. Secondly, The inner sleeve is limited by the limiting assembly to prevent it from shaking and loosening. An electrode is set at the vertex of the inner and outer sleeve clamping assemblies. Punctate ablation.

Description

A bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation

technical field

The invention relates to the technical field of ablation forceps, in particular to a bipolar pulse electric field ablation isolation forceps capable of linear and point ablation.

Background technique

Ablation therapy is currently the main way to treat tachyarrhythmias in clinical practice. The current clinical ablation and damage methods mainly include: radiofrequency ablation, cryoablation, microwave ablation, ultrasound ablation, laser ablation, etc. The most mature and widely used technology is only radiofrequency ablation and cryoablation. However, both radiofrequency and cryotherapy damage tissue by means of "heat energy", which is not selective. Therefore, in order to avoid damage to blood vessels when ablating adjacent large blood vessels, the ablation is often incomplete, which reduces the success rate of treatment. In addition, due to anatomical reasons, the current surgical ablation of atrial fibrillation is usually based on bipolar radiofrequency ablation, supplemented by monopolar ablation or cryoablation. It is completed by monopolar ablation or cryoablation. Therefore, multiple devices and tools are often used at the same time, which increases the operation and cost.

Pulsed electric field ablation is a non-"thermal" method that causes irreversible electroporation of the cell membrane to specifically damage the target cells, and has the characteristics of not damaging the extracellular matrix. At the same time, because different cells have different thresholds for irreversible electroporation, this difference can be used to achieve the selectivity of cell damage types. Studies have shown that the threshold for irreversible electroporation of cardiomyocytes is low, and pulsed electric field ablation can achieve selective cardiomyocyte injury without involving blood vessels. Therefore, the use of pulsed electric field ablation can overcome the shortage of "thermal energy" such as radio frequency and freezing, and improve the safety of ablation in the adjacent blood vessel area.

In addition, most of the common ablation forceps on the market currently use a fixed forceps body, that is, the distal and proximal forceps are parallel to each other. Uneven force affects the homogeneous effectiveness of ablation, some excessive ablation occurs, increasing the chance of complications, and some damage is insufficient, which affects the treatment effect.

SUMMARY OF THE INVENTION

The present invention aims to solve the shortcomings existing in the background technology, and provides a bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation. The pulsed electric field is used as the ablation method to selectively damage myocardial cells without affecting the blood vessels. Features, improve the safety of ablation in the area adjacent to the blood vessel. The proximal and distal ablation clamps are provided with clamping grooves, and a clamping spring is arranged between them, which overcomes the uneven adherence force of the rigid clamps due to different myocardial thicknesses, and ensures that the ablation clamps are evenly attached to the tissue. At the top of the proximal and distal ablation clamps, there are point electrodes, respectively, which are used as one pole of pulse ablation to perform point ablation where it is inconvenient for the clamp to ablate linearly.

In order to achieve the above object, the present invention provides the following technical solutions, a bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation, comprising: a main body; an outer sleeve, the outer sleeve is arranged at the bottom of the main body; wherein, The outer sleeve is internally slidably connected with an inner sleeve for cooperating with the outer sleeve to clamp and ablate the tissue; and a clamping assembly, the clamping assembly is provided at the ends of the outer sleeve and the inner sleeve, For stable clamping of tissues of various sizes.

Further, the clamping assembly includes: a distal clamp disposed at the end of the outer sleeve, a proximal clamp disposed at the end of the inner sleeve; respectively opened at the bottom of the proximal clamp and the Several clamping grooves on the top of the distal clamp; slidingly connected to clamping blocks inside the clamping grooves, and clamping springs are arranged at the bottom of the clamping blocks between the inner walls of the clamping grooves.

Further, the main body is provided with a limiting component for limiting and fixing the inner sleeve, and the limiting component includes: an adjustment groove opened on one side of the bottom of the main body, and the adjustment groove slides inside. A sliding block is connected, and a positioning block is arranged on one side of the sliding block; a plurality of positioning grooves are opened on one side of the inner sleeve, and the positioning grooves are matched with the positioning block; set on the outer sleeve and the return spring between the inner sleeve.

Further, a linear electrode is provided at one end of the clamping block away from the clamping spring for linear ablation, a point electrode for pulse ablation is provided at the top of the distal clamp, and the proximal clamp is provided with a point electrode for pulse ablation. There is also a point electrode for pulse ablation at the top of the device, and the two point electrodes can be adapted to perform point pulse ablation.

Further, the main body is divided into a front half and a rear half, the front half of the main body is provided with a mounting block, and the rear half of the main body is provided with a mounting groove matching the mounting block.

Further, limit slots are provided on the inner walls of both sides of the outer sleeve, limit blocks are provided on both sides of the inner sleeve, and the limit blocks are slidably connected with the limit slots.

Further, the top of the inner sleeve is provided with a push plate, and the top of the push plate is provided with several anti-skid lines.

The invention provides a bipolar pulse electric field ablation isolation forceps capable of linear and point ablation, which has the following beneficial effects:

The advantage of the present invention lies in that, the proximal clamp is pushed toward the direction of the distal clamp on the outer sleeve through the inner cannula, and the tissue that needs to be ablated is clamped by the clamping component, so as to improve the homogeneity of the ablation treatment , and secondly, the inner sleeve is limited by the limit component to prevent it from shaking and loosening.

Description of drawings

FIG. 1 is a schematic diagram of the overall structure of the present invention.

FIG. 2 is a cross-sectional view of the overall structure of the present invention.

FIG. 3 is a side sectional view of the overall structure of the present invention.

FIG. 4 is an enlarged schematic view of the position A in FIG. 2 of the present invention.

FIG. 5 is an enlarged schematic diagram of the position B in FIG. 3 of the present invention.

FIG. 6 is a schematic diagram of the disassembly of the main structure of the present invention.

In Figure 1-6: 1. Main body; 101, Outer casing; 102, Distal clamp; 103, Limit groove; 104, Mounting block; 2, Inner casing; 201, Push plate; 202, Return spring; 203 , proximal clamp; 204, limit block; 205, positioning slot; 3, adjustment slot; 301, slider; 302, positioning block; 4, clamping slot; 401, clamping block; 402, clamping spring; 5 , Point electrodes; 501, Line electrodes.

Detailed ways

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, but not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work fall within the protection scope of the present application.

In the description of this application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", " rear, left, right, vertical, horizontal, top, bottom, inside, outside, clockwise, counterclockwise, etc., or The positional relationship is based on the orientation or positional relationship shown in the accompanying drawings, which is only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, Therefore, it should not be construed as a limitation on this application. In addition, the terms "first" and "second" are only used for descriptive purposes, and should not be construed as indicating or implying relative importance or implying the number of indicated technical features. Thus, features defined as "first", "second" may expressly or implicitly include one or more of said features. In the description of the present application, "plurality" means two or more, unless otherwise expressly and specifically defined.

In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "installed", "connected" and "connected" should be understood in a broad sense, for example, it may be a fixed connection or a detachable connection Connection, or integral connection; it can be mechanical connection, electrical connection or can communicate with each other; it can be directly connected or indirectly connected through an intermediate medium, it can be the internal communication of two elements or the interaction of two elements relation. For those of ordinary skill in the art, the specific meanings of the above terms in this application can be understood according to specific situations.

In this application, unless otherwise expressly specified and defined, a first feature "on" or "under" a second feature may include direct contact between the first and second features, or may include the first and second features Not directly but through additional features between them. Also, the first feature being "above", "over" and "above" the second feature includes the first feature being directly above and obliquely above the second feature, or simply means that the first feature is level higher than the second feature. The first feature is "below", "below" and "below" the second feature includes the first feature being directly below and diagonally below the second feature, or simply means that the first feature has a lower level than the second feature.

The following disclosure provides many different embodiments or examples for implementing different structures of the present application. To simplify the disclosure of the present application, the components and arrangements of specific examples are described below. Of course, they are only examples and are not intended to limit the application. Furthermore, this application may repeat reference numerals and/or reference letters in different instances for the purpose of simplicity and clarity, and does not in itself indicate a relationship between the various embodiments and/or arrangements discussed. In addition, this application provides examples of various specific processes and materials, but one of ordinary skill in the art will recognize the application of other processes and/or the use of other materials.

The embodiment of the present application provides a bipolar pulsed electric field ablation isolation forceps that can be ablated linearly or punctually and can be ablated linearly and punctually. The bipolar pulsed electric field ablation isolation forceps that can be ablated linearly and punctually The tube pushes the proximal clamp toward the distal clamp on the outer sleeve, and uses the clamping component to clamp the tissue that needs to be ablated, so as to improve the stability and homogeneity of the ablation treatment. The position component limits the inner sleeve to prevent it from shaking and loosening. The bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation will be described in detail below. It should be noted that the description order of the following embodiments is not intended to limit the preferred order of the embodiments.

The present application will be described in detail below with reference to the accompanying drawings and specific embodiments. Please refer to FIGS. 1-6 , the present embodiment provides a bipolar pulsed electric field ablation isolation forceps that can be ablated linearly or in dotted lines and in dotted shapes. It should be noted that, in this embodiment, pulsed electric field energy is used instead of RF energy to ablate the patient's diseased part. PFA refers to pulsed electric field ablation. Abnormal substance exchange leads to death, but it will not cause damage to non-cellular fibrous tissue, so it can well maintain the structural integrity of non-cellular fibrous tissue while causing cell necrosis. Referring to this product, first, a catheter is used to conduct the pulsed electric field between the proximal clamp 203 and the distal clamp 102, and the two rows of electrode points designed on the two clamps are used to realize the linearity of the clamped tissue. Pulse electric field ablation treatment; second, bite the inner and outer sleeves, contact the top of the clamp to the tissue, and perform point ablation of the contacted tissue through the point electrodes on the top of the clamp of the inner and outer sleeves. Specifically, the bipolar pulsed electric field ablation isolation forceps for linear and point ablation provided by the present invention includes a main body 1; an outer sleeve 101, and the outer sleeve 101 is arranged at the bottom of the main body 1; The tube 101 is matched with the inner cannula 2 for clamping and ablating the tissue; and the clamping component, which is provided at the ends of the outer cannula 101 and the inner cannula 2 for stable clamping of tissues of various sizes.

In this embodiment, the bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation mainly includes a main body 1, an outer sleeve 101, a distal clamp 102, an inner sleeve 2, a proximal clamp 203, and a clamping assembly and limit components. Push the proximal clamp to approach the distal clamp on the outer sleeve through the inner cannula, and use the clamping component to clamp the tissue that needs to be ablated, so as to improve the stability of the ablation treatment and avoid its deviation. , the inner sleeve is limited by the limit component to prevent it from shaking and loosening.

The clamping components of the bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation include a distal clamp 102 arranged at the end of the outer sleeve 101, a proximal clamp 203 arranged at the end of the inner sleeve 2, The ends of the end clamp 102 and the proximal clamp 203 are respectively provided with a positive electrode point and a negative electrode point for pulse ablation; a plurality of clamping grooves 4 are respectively opened at the bottom of the proximal clamp 203 and the top of the distal clamp 102; It is slidably connected to a clamping block 401 inside the clamping groove 4 , and a clamping spring 402 is provided at the bottom of the clamping block 401 between the inner walls of the clamping groove 4 . During use, the user presses the inner sleeve 2 to make the inner sleeve 2 squeeze the return spring 202 to move downward, and then push the proximal clamp 203 to move in the direction of the distal clamp 102. Using the proximal clamp 203 The two-pulse electric field ablation treatment of the tissue is performed in close proximity to the distal clamp 102 . During the ablation process of the proximal clamp 203 and the distal clamp 102 approaching each other, the clamping block 401 will move toward the direction of the clamping spring 402 under the push of the tissue. At this time, the clamping block 401 will have a continuous clamping force in the direction of the tissue under the push of the clamping spring 402, and then the proximal clamp 203 and the distal clamp 102 are fixed by clamping the tissue by the plurality of clamping blocks 401. , enabling it to fit and ablate tissues of various sizes.

The limit component of the bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation is used to limit and fix the inner sleeve 2. A slider 301 is slidably connected inside, and a positioning block 302 is arranged on one side of the slider 301; a plurality of positioning grooves 205 are opened on one side of the inner sleeve 2, and the positioning grooves 205 are matched with the positioning block 302; The return spring 202 between the inner sleeve and the inner sleeve 2 . During use, after the proximal clamp 203 and the distal clamp 102 are clamped on the tissue, the user can drive the positioning block 302 to move toward the positioning groove 205 by pushing the slider 301, and then the positioning block 302 and the positioning The insertion of the groove 205 is used to limit the position of the inner sleeve 2, so as to prevent the proximal clamp 203 from being displaced during the ablation process, resulting in unsmooth ablation and even affecting the patient's health.

In some embodiments, a linear electrode 501 is provided at one end of the clamping block away from the clamping spring for linear ablation, a point electrode 5 for pulse ablation is provided at the top of the distal clamp, and the top of the proximal clamp is also A point-shaped electrode 5 for pulse ablation is provided, and the point-shaped pulse ablation can be adapted between the two point-shaped electrodes 5. Pulse ablation is done in conjunction with energization.

In some embodiments, the main body 1 is divided into a front half and a rear half, and the front half of the main body 1 is provided with a mounting block 104 , and the rear half of the main body 1 is provided with a mounting groove matching the mounting block 104 . , the front half of the main body 1 and the rear half of the main body 1 can be inserted together through the insertion of the installation block 104 and the installation slot to form a stable main body 1, and when the device fails and needs to be maintained, the user By breaking apart the main body 1 laterally, the front half of the main body 1 and the rear half of the main body 1 can be separated from each other, thereby facilitating the maintenance of the ablation forceps and improving the practicability of the product.

In some embodiments, limit slots 103 are formed on the inner walls of both sides of the outer sleeve 101 , limit blocks 204 are provided on both sides of the inner sleeve 2 , and the limit blocks 204 are slidably connected with the limit slots 103 . The mutual cooperation between the limit block 204 and the limit groove 103 makes the inner sleeve 2 only move in the vertical direction along the limit groove 103, but cannot rotate in the axial direction, so as to prevent the inner sleeve 2 from moving in the vertical direction. During the sliding process, the offset rotation causes the proximal clamp 203 to also generate offset rotation, and finally a situation that cannot correspond to the distal clamp 102 occurs, thereby improving the practicability of the product.

In some embodiments, the top of the inner sleeve 2 is provided with a push plate 201, and the top of the push plate 201 is provided with several anti-skid lines. It can improve the frictional force between the push plate 201 and the user's fingers, so that the user can better exert force on the push plate 201 and the inner sleeve 2, thereby improving the convenience of use of the product.

In the above-mentioned embodiments, the description of each embodiment has its own emphasis. For parts that are not described in detail in a certain embodiment, reference may be made to the relevant descriptions of other embodiments.

A bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation provided by the embodiments of the present application has been described in detail above. The principles and implementations of the present application are described with specific examples in this paper. The descriptions of the examples are only used to help understand the technical solutions of the present application and their core ideas; those of ordinary skill in the art should understand that they can still modify the technical solutions described in the foregoing embodiments, or perform some technical features on them. Equivalent replacement; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application.

Claims (7)

1. a bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation, is characterized in that, comprising: main body; an outer sleeve, the outer sleeve is arranged at the bottom of the main body; Wherein, the outer sleeve is internally slidably connected with an inner sleeve for cooperating with the outer sleeve to clamp and ablate the tissue; and A clamping assembly is provided at the ends of the outer sleeve and the inner sleeve, and is used for stable clamping of tissues of various sizes. 2 . The bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation according to claim 1 , wherein the clamping assembly comprises: a distal clamp arranged at the end of the outer sleeve, and a proximal clamp arranged at the end of the inner sleeve; a plurality of clamping grooves respectively opened at the bottom of the proximal clamp and the top of the distal clamp; The clamping block is slidably connected to the interior of the clamping groove, and a clamping spring is arranged at the bottom of the clamping block between the inner walls of the clamping groove. 3 . The bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation according to claim 1 , wherein the main body is provided with a limiting component for limiting and fixing the inner sleeve. 4 . , the limiting component includes: an adjustment groove opened on one side of the bottom of the main body, a sliding block is slidably connected inside the adjustment groove, and a positioning block is arranged on one side of the sliding block; Several positioning grooves are opened on one side of the inner sleeve, and the positioning grooves are matched with the positioning block; A return spring is provided between the outer sleeve and the inner sleeve. 4 . The bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation according to claim 2 , wherein a linear electrode is provided at one end of the clamping block away from the clamping spring for performing linear For ablation, the tip of the distal clamp is provided with a point electrode for pulse ablation, and the top of the proximal clamp is also provided with a point electrode for pulse ablation, and the two point electrodes can be adapted Perform punctate pulse ablation. 5 . The bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation according to claim 1 , wherein the main body is divided into a front half and a back half, and the front half of the main body is provided with An installation block, the rear half of the main body is provided with an installation groove matching the installation block. 6 . The bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation according to claim 1 , wherein limit slots are provided on the inner walls of both sides of the outer sleeve, and two sides of the inner sleeve are provided with A limit block is slidably connected with the limit slot. 7 . The bipolar pulsed electric field ablation isolation forceps capable of linear and point ablation according to claim 1 , wherein a push plate is provided on the top of the inner sleeve, and a number of anti-skid strips are provided on the top of the push plate. 8 . texture.

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