CN1150941C - Drug for treating rheumatism - Google Patents
Drug for treating rheumatismInfo
- Publication number
- CN1150941C CN1150941C CNB021341125A CN02134112A CN1150941C CN 1150941 C CN1150941 C CN 1150941C CN B021341125 A CNB021341125 A CN B021341125A CN 02134112 A CN02134112 A CN 02134112A CN 1150941 C CN1150941 C CN 1150941C
- Authority
- CN
- China
- Prior art keywords
- radix
- medicine
- rheumatism
- treating medicine
- root
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003814 drug Substances 0.000 title claims abstract description 22
- 229940079593 drug Drugs 0.000 title description 4
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 241001446509 Psoralea Species 0.000 claims abstract description 7
- 241000219780 Pueraria Species 0.000 claims abstract description 7
- 241000903946 Clematidis Species 0.000 claims description 9
- 241000756943 Codonopsis Species 0.000 claims description 9
- 230000000694 effects Effects 0.000 abstract description 5
- 208000002193 Pain Diseases 0.000 abstract description 3
- 210000000988 bone and bone Anatomy 0.000 abstract description 3
- 208000006820 Arthralgia Diseases 0.000 abstract description 2
- 208000001132 Osteoporosis Diseases 0.000 abstract description 2
- 239000008280 blood Substances 0.000 abstract description 2
- 210000004369 blood Anatomy 0.000 abstract description 2
- 230000017531 blood circulation Effects 0.000 abstract description 2
- 210000003205 muscle Anatomy 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 241000427159 Achyranthes Species 0.000 abstract 1
- 244000189799 Asimina triloba Species 0.000 abstract 1
- 235000006264 Asimina triloba Nutrition 0.000 abstract 1
- 235000009467 Carica papaya Nutrition 0.000 abstract 1
- 241000218158 Clematis Species 0.000 abstract 1
- 244000163122 Curcuma domestica Species 0.000 abstract 1
- 235000003392 Curcuma domestica Nutrition 0.000 abstract 1
- 241000893536 Epimedium Species 0.000 abstract 1
- 230000002301 combined effect Effects 0.000 abstract 1
- 235000003373 curcuma longa Nutrition 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 235000018905 epimedium Nutrition 0.000 abstract 1
- 235000013976 turmeric Nutrition 0.000 abstract 1
- 238000010298 pulverizing process Methods 0.000 description 8
- 238000004519 manufacturing process Methods 0.000 description 5
- 206010013786 Dry skin Diseases 0.000 description 4
- 239000006071 cream Substances 0.000 description 4
- 238000001035 drying Methods 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 239000000706 filtrate Substances 0.000 description 4
- 239000000796 flavoring agent Substances 0.000 description 4
- 235000019634 flavors Nutrition 0.000 description 4
- 235000013312 flour Nutrition 0.000 description 4
- 239000008187 granular material Substances 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 229940071462 oralone Drugs 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 208000012659 Joint disease Diseases 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 235000018927 edible plant Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a rheumatism treating medicine which uses epimedium, cibot rhizome, clematis root, achyranthes root, pueraria root, pilose asiabell root, turmeric, psoralea fruit and pawpaw as raw materials. The prescription of the rheumatism treating medicine is formed according to a seedling medicine theory, and rheumatism is treated by the combined effect of components. The rheumatism treating medicine has no toxic and side effect on a human body, the rheumatism treating medicine can strengthen bones and muscles, expel wind and dampness, activate blood circulation, dissipate blood stasis, dredge channels and lighten pain, and the rheumatism treating medicine has significant effect on wind-cold-dampness arthralgia, waist and leg aching pain, numb limb, osteoporosis, etc.
Description
Technical field
The present invention relates to the rheumatismal medicine of a kind of treatment, relating in particular to a kind of is the Chinese patent medicine of feedstock production with the Chinese herbal medicine.
Background technology
The World Health Organization (WHO) is decided to be 10 years of bone and joint with 21 century first 10 years (2001-2010), and has comprised the joint diseases of a large amount of different causes of disease, different mechanisms, different pathological in the rheumatology.Chronic, progressivity process that joint diseases mostly is, the number of falling ill along with the prolongation of human longevity increases, many patients have often lost enjoyment and equal working opportunity and the family's wellbeing of normal person in the vigorous age of life, bear very big economy, spirit and mental pressure.The rheumatismal medicine of treatment adopts the oral administration and externally method more at present, but slow curative effect, and certain toxic and side effects is arranged.
Summary of the invention
The object of the present invention is to provide a kind of bone and muscle strengthening that has, wind-damp dispelling, blood circulation promoting and blood stasis dispelling, the therapeutic agent for rheumatic disease of dredging collateral to stop pain.
Solution of the present invention is based on Seedling medicine theoretical understanding and Therapeutic Principle to rheumatism mechanism, with reference to modern medicine pharmacological research achievement, filters out natural edible plant amedica, carries out prescription according to Seedling medicine theory and makes.
Medicine of the present invention is to be made by the component of following weight (part) proportioning:
Herba Epimedii 30～50 Rhizoma Cibotii 22.5～37.5 Radix Clematidis 15～25
Radix Achyranthis Bidentatae 11～18.5 Radix Puerariaes 19～31 Radix Codonopsis 11～18.5
Rhizoma Curcumae Longae 11～18.5 Fructus Psoraleaes 15～25 Fructus Chaenomeliss 11～18.5
Preparing pharmaceutical formulation preferred weight of the present invention (part) ratio range is:
Herba Epimedii 35～45 Rhizoma Cibotii 26.5～33.5 Radix Clematidis 17.5～22.5
Radix Achyranthis Bidentatae 13～16.5 Radix Puerariaes 24～27 Radix Codonopsis 13～16.5
Rhizoma Curcumae Longae 13～16.5 Fructus Psoraleaes 17.5～22.5 Fructus Chaenomeliss 13～16.5
Optimum weight (part) proportioning for preparing pharmaceutical formulation of the present invention is:
Herba Epimedii 40 Rhizoma Cibotii 30 Radix Clematidis 20
Radix Achyranthis Bidentatae 15 Radix Puerariaes 25 Radix Codonopsis 15
Rhizoma Curcumae Longae 15 Fructus Psoraleaes 20 Fructus Chaenomeliss 15
Above-mentioned each component is made medicine production method of the present invention is:
1, get the Radix Puerariae oven dry, pulverizing is crossed 80 mesh sieves, and flour extraction is 65%, and is standby;
2, all the other eight flavors add 8 times of water gagings decoctions 3 times, each 1.5 hours, collecting decoction filtered, relative density was 1.20～1.28 thick paste when filtrate was concentrated into 40 ℃, put coldly, yield is about 8% by dried cream, adds above-mentioned fine powder in thick paste, mixing, in 80 ℃ of dryings, pulverizing, cross 60 mesh sieves, granulate;
3, encapsulated, promptly get drug capsules agent of the present invention.
The present invention can make dosage forms such as tablet, electuary with general conventional formulation method.
Medicine of the present invention, selecting natural plant for use is raw material, utilizes the comprehensive function treatment rheumatism of each component, human body is had no side effect, and cheap.Clinical observation shows that anemofrigid-damp arthralgia, waist and leg ache, numb limbs and tense tendons, osteoporosis etc. are had significant effect.
The specific embodiment
Embodiment 1
Take by weighing raw material by following proportioning:
Herba Epimedii 400g Rhizoma Cibotii 300g Radix Clematidis 200g
Radix Achyranthis Bidentatae 150g Radix Puerariae 250g Radix Codonopsis 150g
Rhizoma Curcumae Longae 150g Fructus Psoraleae 200g Fructus Chaenomelis 150g
Production method is as follows: get the Radix Puerariae oven dry, pulverizing is crossed 80 mesh sieves, and flour extraction is 65%, and is standby; All the other eight flavors add 8 times of water gagings and decoct 3 times, and each 1.5 hours, collecting decoction filtered, relative density was 1.20～1.28 thick paste when filtrate was concentrated into 40 ℃, put coldly, and yield is about 8% by dried cream, added above-mentioned fine powder in thick paste, mixing in 80 ℃ of dryings, pulverizing, is crossed 60 mesh sieves, granulate; Encapsulated, every the dress 0.3g, oral one time 3,3 times on the one.
Embodiment 2
Take by weighing raw material by following proportioning:
Herba Epimedii 300g Rhizoma Cibotii 225g Radix Clematidis 150g
Radix Achyranthis Bidentatae 110g Radix Puerariae 190g Radix Codonopsis 110g
Rhizoma Curcumae Longae 110g Fructus Psoraleae 150g Fructus Chaenomelis 110g
Production method is as follows: get the Radix Puerariae oven dry, pulverizing is crossed 80 mesh sieves, and flour extraction is 65%, and is standby; All the other eight flavors add 8 times of water gagings and decoct 3 times, and each 1.5 hours, collecting decoction filtered, relative density was 1.20～1.28 thick paste when filtrate was concentrated into 40 ℃, put coldly, and yield is about 8% by dried cream, added above-mentioned fine powder in thick paste, mixing in 80 ℃ of dryings, pulverizing, is crossed 60 mesh sieves, granulate; Encapsulated, every the dress 0.3g, oral one time 3,3 times on the one.
Embodiment 3
Take by weighing raw material by following proportioning:
Herba Epimedii 500g Rhizoma Cibotii 375g Radix Clematidis 250g
Radix Achyranthis Bidentatae 185g Radix Puerariae 310g Radix Codonopsis 185g
Rhizoma Curcumae Longae 185g Fructus Psoraleae 250g Fructus Chaenomelis 185g
Production method is as follows: get the Radix Puerariae oven dry, pulverizing is crossed 80 mesh sieves, and flour extraction is 65%, and is standby; All the other eight flavors add 8 times of water gagings and decoct 3 times, and each 1.5 hours, collecting decoction filtered, relative density was 1.20～1.28 thick paste when filtrate was concentrated into 40 ℃, put coldly, and yield is about 8% by dried cream, added above-mentioned fine powder in thick paste, mixing in 80 ℃ of dryings, pulverizing, is crossed 60 mesh sieves, granulate; Encapsulated, every the dress 0.3g, oral one time 3,3 times on the one.
Claims (3)
1, the rheumatismal medicine of a kind of treatment is characterized in that it is made by the following weight proportion raw material:
Herba Epimedii 30～50 Rhizoma Cibotii 22.5～37.5 Radix Clematidis 15～25
Radix Achyranthis Bidentatae 11～18.5 Radix Puerariaes 19～31 Radix Codonopsis 11～18.5
Rhizoma Curcumae Longae 11～18.5 Fructus Psoraleaes 15～25 Fructus Chaenomeliss 11～18.5.
2, the rheumatismal medicine of treatment as claimed in claim 1 is characterized in that the weight proportion of each raw material is:
Herba Epimedii 35～45 Rhizoma Cibotii 26.5～33.5 Radix Clematidis 17.5～22.5
Radix Achyranthis Bidentatae 13～16.5 Radix Puerariaes 24～27 Radix Codonopsis 13～16.5
Rhizoma Curcumae Longae 13～16.5 Fructus Psoraleaes 17.5～22.5 Fructus Chaenomeliss 13～16.5.
3, the rheumatismal medicine of treatment as claimed in claim 1 is characterized in that the weight proportion of each raw material is:
Herba Epimedii 40 Rhizoma Cibotii 30 Radix Clematidis 20
Radix Achyranthis Bidentatae 15 Radix Puerariaes 25 Radix Codonopsis 15
Rhizoma Curcumae Longae 15 Fructus Psoraleaes 20 Fructus Chaenomeliss 15.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021341125A CN1150941C (en) | 2002-11-16 | 2002-11-16 | Drug for treating rheumatism |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021341125A CN1150941C (en) | 2002-11-16 | 2002-11-16 | Drug for treating rheumatism |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1413700A CN1413700A (en) | 2003-04-30 |
| CN1150941C true CN1150941C (en) | 2004-05-26 |
Family
ID=4747567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB021341125A Expired - Lifetime CN1150941C (en) | 2002-11-16 | 2002-11-16 | Drug for treating rheumatism |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1150941C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022232413A1 (en) * | 2021-04-28 | 2022-11-03 | Arrmaz Products, Inc. | Novel chemistries to achieve a total agronomic coating containing micronutrients and/or biocatalysts |
-
2002
- 2002-11-16 CN CNB021341125A patent/CN1150941C/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022232413A1 (en) * | 2021-04-28 | 2022-11-03 | Arrmaz Products, Inc. | Novel chemistries to achieve a total agronomic coating containing micronutrients and/or biocatalysts |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1413700A (en) | 2003-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: BAILING ENTERPRISE GROUP PHARMACY CO., LTD., GUIZ Free format text: FORMER OWNER: GUIZHOU HERENTANG PHARMACEUTICAL CO., LTD. Effective date: 20061103 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20061103 Address after: 561000 Guizhou Province, Anshun City West Economic and Technological Development Zone Avenue Patentee after: GUIZHOU BAILING ENTERPRISE GROUP PHARMACEUTICAL CO.,LTD. Address before: 550201 Guizhou city of Guiyang province Zhazuo Xiuwen County Pharmaceutical Industrial Park Patentee before: GUIZHOU HERENTANG PHARMACEUTICAL Co.,Ltd. |
|
| ASS | Succession or assignment of patent right |
Owner name: BRAUN GUIZHOU PHARMACEUTICAL ENTERPRISE GROUP CO. Free format text: FORMER OWNER: BAILING ENTERPRISE GROUP PHARMACY CO., LTD., GUIZHOU Effective date: 20080530 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20080530 Address after: Guizhou province Anshun City West Economic and Technological Development Zone Avenue Patentee after: GUIZHOU BAILING ENTERPRISE GROUP PARMACEUTIAL Co.,Ltd. Address before: Guizhou province Anshun City West Economic and Technological Development Zone Avenue Patentee before: GUIZHOU BAILING ENTERPRISE GROUP PHARMACEUTICAL CO.,LTD. |
|
| CX01 | Expiry of patent term |
Granted publication date: 20040526 |
|
| CX01 | Expiry of patent term |