CN1149935C

CN1149935C - Chinese-medicinal additive of feed

Info

Publication number: CN1149935C
Application number: CNB001287265A
Authority: CN
Inventors: 梅茂伍
Original assignee: Individual
Current assignee: Individual
Priority date: 2000-09-10
Filing date: 2000-09-10
Publication date: 2004-05-19
Anticipated expiration: 2020-09-10
Also published as: CN1342416A

Abstract

The present invention discloses a method for preparing a Chinese herbal medicine feed additive, which adopts traditional Chinese medicine theories of five element theory, visceral manifestation, qi and blood, essence, fluid, etc. The present invention is based on the artificial law of the spleen and stomach according to the relation of qi, blood, yin and yang of other viscera, adopts a thought for supporting healthy energy to eliminate evil on the immunity, and regulates qi and blood of viscera, the artificial law of the spleen and stomach. When the feed additive is actually used, the present invention complies with three-reason suiting measures to different conditions. The feed additive is used for preparing a series of additives prepared from a plurality of Chinese herbal medicines, does not contain substances of hormone, antibiotic, etc. and has the characteristics of high speed of promoting the growth of poultry and fowls, good effect on preventing and treating diseases, low cost and simple technology.

Description

Chinese herbal feed additive

Technical field:

The present invention relates to a kind of compound method that is used for the feed addictive of aquaculture.

Background technology:

The feed addictive of Chu Shouing is according to the effect difference in the market, and be divided into two big classes usually: a class is a nutritive additive, comprises amino acid, mineral matter and vitamin etc.; Another kind of is non-nutritive additive, comprises growth promoter, vermifuge, animal products quality improving agent etc.

Belong to health care and growth promoter class with institute of the present invention feed prepared additive, examples of such additives comprises antibiotic, synthesising bacteria anti-reflecting medicine, pest repellant and Chinese herbal medicine and hormone etc.The antibiosis that is used for feed addictive industry at present have tens kinds of medicines such as Tetracyclines, aminoglycosides, the synthesising bacteria anti-reflecting medicine that uses has olaquindox (educating spirit soon), furazolidone (furazolidone) etc., the hormone that is used for aquaculture has gonadal steroids and analog thereof, growth hormone, beta-Adrenergic agonists etc., Chinese herbal feed additive belongs to frontier branch of science, theoretical ripe, effect is fine, and social widely used prescription is also few.

Chinese herbal medicine is animal and plant or mineral, mostly contains rich in amino acid, mineral matter, vitamin, and being used for feed addictive can supplement the nutrients, promote growth of animals or poultry, and do not contain hormone, antibiotic, and advantage such as the medicine source is abundant, can be widely used in aquaculture.

Summary of the invention:

Purpose of the present invention is exactly in order to change China's wide geographic area, especially rural area existing " bucket rice jin chicken ", the breed approach that extensive cultivation is extensive.Tradition aquaculture a large amount of food consumptions cause the great wasting of resources keeping aspect the consumption of livestock and poultry life.The present invention is exactly in order to save food and to promote growth of animals or poultry, having improved labor productivity thereby reduce feed cost.China natural resources is abundant, but annual import feed addictive has spent the foreign exchange of many preciousnesses, makes us holding one's own wrist and exhales pain, in the face of fund, the technical advantage of developed country's feed industry, we should excavate Chinese nation's excellent culture precious deposits, utilize the traditional Chinese medicine unique advantage to create social economic value.Produce with institute of the present invention feed prepared additive investment for a short time, income is big, thereby can alleviate the employment pressure chance that creates more jobs, service society to a certain extent.

For realizing this purpose, the present invention is guidance with the tcm theory, makes feed addictive with pure Chinese medicine, reaches the promotion growth of animals or poultry, prevents and treats the effect of its disease.Its characteristics of the feed addictive that is made into are as follows:

The first, the general characteristic that has Chinese medicine:

1. be the summary of daily life experience.

2. practicality, practical.

3. be that the national culture part is inherited to debate and Fa Zhan not.

The second, be that its processing technology is simple, and is with low cost by certain being processed into of Chinese herbal medicine process with feed prepared additive of the present invention, after preparation, drying does not pack and can lose efficacy.

Three, the natural resources of Chinese medicinal materials of China is abundant, comprises animal and plant and mineral, and many crude drugs can be made feed addictive, with the processing technology complexity that the additive of selling in the market has, dependence on import is gone back in the source that has, the price height, shelf-life is short, and the present invention more preponderates by contrast.

Four, made by the Chinese herbal medicine that has no side effect with the additive of the present invention's preparation, can not have poisonous residuals in the product of breed body, the excreta of culturing in the product growth course can not work the mischief to environment yet, and it belongs to green feed additive.

The present invention used traditional Chinese medicine yin-yang and five elements, hide resemble, gas, blood, body fluid scheduling theory.The theory of yin-yang and five elements (metal, wood, water, fire and earth) demonstrates fully on other theoretical foundation as total guiding principle.

Gas, blood, body fluid are that to constitute body be again the base substance of keeping the organism physiology activity, and it generates from the food of being taken in, the essence of water and grain that generates through the digestion of taste, absorption.Under the normal physiological situation, the metabolism of body fluid is the absorption by stomach, the fortuneization of board and transferring, and a surname of lung sends out with respectful and falls, and the transpiration gasification of kidney is a passage with three warmers, is transported to whole body body fluid after metabolism and then turns to sweat, urine and gas and excrete.

Kidney be negative and positive this, Source of life, be the congenital foundation.The major physiological function is store essential substances, main growing and reproduction and the metabolism of water liquid.Essence in kidney has the function that promotes that body growth is grown.

Taste, lasting gentle, the blood of body life, the biochemistry of body fluid all depend on the fortuneization of taste, so taste are source of generating QI and blood, the foundation of acquired constitution.It is plentiful that the muscle of whole body all will rely on the essence of water and grain of board stomach fortune to come nutrition just can develop muscles.

A surname of lung send out with the respectful major function of falling be that body fluid and the essence of water and grain that trump card transfers is distributed to whole body, reach outward in fur, downwards spreading is in four limbs, all keys of bones of the body collectively and body.

In sum, the functional activity of each internal organs be unable to do without the essence of water and grain of taste fortune, in the traditional Chinese medicine " spleen-YANG being rooted in kidney-YANG ", it all is in order to promote the fortune function of taste to help transporting and transforming function of the spleen and stomach essence of water and grain etc. that " earlier born the day after tomorrow ", the Xuan Fasu of lung fall the defeated cloth of cereal nutrient.The present invention makes laws with taste, utilizes the five-element's the gram of giving birth to concern " beneficial fire generating earth ", " harmonizing liver-spleen ".

Say " treatment in accordance with three factors(season,locality and individual) " on the rules of treatment, different moral, weather, different regions, different population medications is also different.According to the feed addictive that the regional climate requirement is made, its scope of application only is confined to act under its condition, and has the breed of promotion body speed of production characteristics faster.Make full use of traditional Chinese medical science organic conception and dialectics thought, the traditional Chinese medical science has avoiding cold wearher while using drugs of cold nature, and what avoid hot weather while using drugs of hot nature says, body and nature are closely linked.The summer weather sweltering heat, yang-energy is contained, and cloudy gas Fu Zang has sweet cold medicine to control yang pathogens, without bitter cold, the thing that impairment of yang is upset one's stomach.Total be exactly the present invention makes a series of feed addictives as required according to top said rule.

Modern study shows that feed prepared additive of the present invention has the function of hypothalamo-pituitary-adrenal axis and hypothalamic-pituitary-thyroid axis to body.More than the physiological disposition division of two axles as follows:

One, thyroid gland mainly promotes organism metabolism and growth and development process, and T3, T4 also promote adenohypophysis secretion auxin, and the latter promote that also long bone grows except that the facilitation of having grown to long bone own.

The major physiological of auxin act as:

1, promotes growth.The growth of body is subjected to the influence of many-sided factor, but wherein auxin is the factor that plays a crucial role.Under mn condition, it can stimulate liver, kidney to produce a kind of micromolecule polypeptide material, is called somatomedin, and it can quicken the synthetic of protein, promotes cartilage-derived growth, and muscle etc. is organized also similar effect.

2, influential to metabolism.(1), promotes that protein is synthetic and reduces its decomposition that this is because it can promote that amino acid enters cell, and can quicken the synthetic of DNA, RNA.(2), fat metabolism is had the permission effect, thereby quicken the decomposition utilization of fat, the fat mass of tissue is reduced.(3), the auxin of physiological level can stimulate secretion of insulin, the utilization of reinforcement sugar.

Insulin is to the metabolism of sugar, promotes the utilization of body tissue to glucose on the one hand, suppresses glycogen on the other hand and decomposes and gluconeogenesis, thereby can reduce blood sugar the storage and the growth of the body energy played an important role.Insulin can also suppress four rate-limiting enzymes in the gluconeogenesis process: glucose-6 diphosphatase, FDPase, PCK and pyruvate carboxylase.

Insulin plays a driving role with storage to the synthetic of fat, thereby also help cell synthetic the helping of amino acid whose picked-up quickening protein is grown.

Two, adrenal cortex, it produces the hormone relevant with energetic supersession has: the glucocorticoid that the zona fasciculata cell produces, reticular zone produces sex hormone.

Glucocorticoid, main effect is the heteroplasia that promotes sugar, its mechanism is:

1., promote extrahepatic tissue protein to be decomposed into amino acid, and short its enters liver cell.

2., increase the activity of four rate-limiting enzymes of gluconeogenesis approach.

3., promote the hydrolysis of fat kulactone fat.

These all help the heteroplasia of sugar, increase the sugar source, so glucocorticoid is the hormone that sugar is raise, it also promotes the absorption of monose in addition.

Testosterone is to the effect of metabolism, mainly is anabolism intraorganic protein such as muscle skeleton synthetic particularly that promotes the body internal protein, increases calcium phosphorus deposition in the bone.

Estrogen influences alcium and phosphor metabolization, and the activity of stimulating osteoblast promotes the synthetic of muscle protein.

Cortisol can also make hydrochloric acid in gastric juice and pepsinia increase in addition, improves appetite of livestock and poultry, promotes digestion.According to feed prepared additive of the present invention.It contains the Radix Astragali, Radix Glycyrrhizae etc. and promotes gastric acid secretion, can increase gastric secretion mucus again, stomach is had protective effect, and be similar to the cortex hormone of aadrenaline effect.Clinical proofs such as cultivated land, the root of straight ladybell, dark plum, these medical instruments have insulinoid effect.

The complete additive of effect also must and have the effect of disease preventing and treating." strengthening vital QI to eliminate pathogenic factors " theory is arranged in the theory of traditional Chinese medical science, and yin-yang theory and viscera-state doctrine and immunity are closely related.

One, strengthening vital QI to eliminate pathogenic factors theory and immunity.

The traditional Chinese medical science is from materialist dialectics viewpoint, in the cause of disease, emphasize the effect of internal cause on the path, with the functional activity of body and the effect of resisting to remove various adverse factors belong to healthy tendency, belong to perverse trend with destroying internal body with the various adverse factors that destroy body and external environment relative balance state.

The Chinese traditional treatment disease, nothing more than setting upright and eliminating evil two big rules, set upright the premunition of transferring body, improve body's immunological function, strengthen its stability, eliminating evil is exactly to get rid of the factor of destroying its immunologic balance, also can suppress immune response, set upright and to improve immunologic function, " it promptly is eliminating evil setting upright ".

Two, yin-yang theory and immunity.

" warp " cloud: " yin and yang in equilibrium; life activities being normally maintained ", " in healthy tendency deposits; heresy can not be done ", negative and positive are adjusted in mutually and get dynamic equilibrium in the unity of opposites, it is normal that thereby the function that makes the vital organs of the human body is tending towards, the immune system of body can be kept the internal physiological balance and stability, and identification and get rid of dissident's material has relation to generation, development and the differentiation of a lot of diseases.

Three, viscera-state doctrine and immunity.

The gas of body is by the congenital vital essence of kidney, and the essential substances from water and cereals of board fortuneization becomes with the clear gas maple that lung sucks, and healthy tendency and lung, spleen, kidney are closely related, and healthy tendency has functions of immune system, thus three dirty and immune in close relations be basic especially with the kidney.

Modern medicine thinks that kidney yang-tonifying medicinal can make low DNA synthetic and increase, and drugs for nourishing yin can make that hyperfunction DNA is synthetic to be reduced.The traditional Chinese medical science is thought the negative and positive of adjusting kidney, can adjust nucleic acid metabolism, thereby regulate immunologic balance, and this testis also forms relevant thymus gland with the T cell to be had close related.Spleen can be had blood under one's command, and main muscle four limbs are body source of generating QI and blood, and the temper operating influence is defended the generation of gas.Modern age, experimental study illustrated that insufficiency of the spleen patient not only had the disorderly phenomenon of functions of intestines and stomach, and its immunologic function is also all low, so use the invigorating the spleen side of regulating the flow of vital energy medicine.

Lung governing qi, department's space between skin and muscles folding, main Xuan Fasu fall, regulating fluid apssage, and lung qi is normal, the space between skin and muscles densification, barrier is consolidated, and heresy can not be invaded, on the contrary Lung Qi deficiency, and then a surname sends out and defends the gas dereliction of duty, outer heresy is taken advantage of a weak point, just can be by the fur impariment of the lung, so lung is with to defend gas relevant with the body non-specific immunity.

The present invention takes into account other based on " setting upright ", promotes the Chinese herbal medicine of immunity to have:

1, Qi-tonifying drug, the Radix Astragali, Radix Codonopsis, the bighead atractylodes rhizome etc. can improve T cell ratio, lymphocyte transformation rate and cytophagous function, increasing leukocyte improves IgG, IgA content.

2, antianaemics, Radix Angelicae Sinensis, the root of herbaceous peony, cultivated land etc. can improve T cell and lymphocyte transformation rate, prolong the antibody life period.

3, yang-tonifying drug, Herba Epimedii, the seed of Chinese dodder, energy such as dried human placenta, Chinese cassia tree can improve T cell ratio and lymphocyte transformation rate, increase phagocytic function and increasing leukocyte, and enhancing antibody forms, and improves the level of IgG, IgA and SIgA.

4, drugs for nourishing yin can improve the ratio and the lymphocyte transformation rate of T cell subsets at asparagus fern, the root of straight ladybell, the tuber of dwarf lilyturf etc., strengthens the function and the increasing leucocyte of macrophage, prolongs the antibody life period and improves the B cell.

The multiple feed addictive of Chu Shouing in the market, some has added the hormone that can promote the cell growth, and as ovarioestrogen, pituitary gonadotropic hormone and thyrotropic hormone etc., these all have carcinogenesis, can cause proliferation of cells and canceration.Edible these livestock and poultry products of people have potential threat to health.These hormones have diethylstilbestrol, thiouracil, estradiol etc.

Some feed addictive has been put into antibiotic such as terramycin, red mould etc., penicillin etc.These antibiotic can produce " suprainfection ", and with resisting immunologic function, some pathogenic bacteria is developed immunity to drugs, bring difficulty, have residual at livestock products to clinical treatment, not only, also can make bacterium develop immunity to drugs indirect hazard people and animals' health directly to the human body toxic side effect.

Some feed addictive, cost is too high, and the composition source that has does not take into full account short length again and matches with disease-resistant also by import when preparation.

In sum, these additives often have the following disadvantages:

One, speed of production, getting fat effect are not fairly obvious.

Two, contain hormone, antibiotic feed addictive, can in culturing the product body, cause residually, consumer's health is directly worked the mischief.

Three, the harmful substance in the excreta of breed product also can cause environmental pollution.

Four, cost height, complex process, economic benefit are not obvious.

With feed prepared additive of the present invention, adopt authentic medicinal herbs, honor is ancient to be concocted, and operations such as drying, pulverizing, stirring packing is finished product.It does not contain harmful substances such as hormone, antibiotic, himself has the function of getting fat, immunity concurrently, and fattening period is short, the efficiency of feed utilization height, and after butchering, meat is good, and taste is fresh and tender, the red Rong Run alive of chromaticness.

The specific embodiment: following only with general side, illustrate that the present invention prepares logos and application effect.

General side forms:

The Radix Astragali 150 grams, the bighead atractylodes rhizome 100 grams, Radix Codonopsis 120 grams, Radix Glycyrrhizae 60 grams, dried orange peel 120 grams, fushen's 150 grams, galangal 100 grams, cooked aconite 50 grams, HERBA EPIMEDII 150 grams, dark plum 100 grams, the fruit of Chinese magnoliavine 150 grams, Radix Angelicae Sinensis 150 grams, cultivated land 150 grams, hawthorn 500 grams, Fructus Hordei Germinatus 500 grams, concha meretricis seu cylinae 250 grams, the nine hole shells of seaear, 250 grams.

The side separates: spleen governing limbs, so with the Radix Astragali, the bighead atractylodes rhizome, Radix Codonopsis, Radix Glycyrrhizae, fushen, sweet temperature invigorating the spleen, galangal, cooked aconite are with the sea of warm five cereals qi and blood, and what strengthen stomach is received the function of becoming thoroughly decomposed, the kidney generating marrow and dominating bone, department grows, with HERBA EPIMEDII, galangal, benefit frame warming and invigorating kidney Yang, because of its fast growth, probably its nutrient QI and blood being insufficient nourishes ying blood with Radix Angelicae Sinensis, cultivated land.Because of liver, kidney homology, the easypro clockwork spring of liver reaches the transporting and transforming function of the spleen and stomach function could be normal, thus with the shell of seaear, concha meretricis seu cylinae to press down liver-yang, " harmonizing liver-spleen ".Hawthorn, Fructus Hordei Germinatus promote digestion.Full side's character is gentle, is with general side, and still relatively warm, we are this with taste, Fang Zhongyou mends and lets out, and has to rise to have to fall, and opposes each other and yet also complement each other, and adjusts internal organs negative and positive of qi and blood relation, reach promotion and culture the object growth, this side is the basis side that the present invention prepared, and other each side all form with this side's plus-minus.

With above-mentioned medicinal material in proportion, through concoct, dry, pulverize, cross No. six sieves and stir evenly packing.This product is warm in nature, acrid-sweet flavor, fragrance, is the grass meal last current state.Contain the required vitamin of carcass, amino acid, inorganic salts, organic acid and some lipid, as lecithin etc.

This product enters carcass product chamber, and saliva stimulating is secreted and stimulated other secretion of digestive juice, and gastric receptive relaxation, for food enters stomach and small intestine, and digestion creates conditions therein, and gastric receptive relaxation, and hot sweet, fragrant flavor can excite the appetite of poultry again.Organic acid in this product can improve the sour environment of stomach, increases the effect of hydrochloric acid, strengthens pepsic activity, thereby further activates other digestive enzyme activities, a little less than the organic acid acidity, does not influence enteral digesting and assimilating.It can also promote the absorption of inorganic salts, and amylase and carbohydrase etc. can both help digestion and the absorption of carcass to feed in this product in addition.

The feed effect is as follows:

The public X of feeding Landrace Taihu Lake pig sow hybridized pig kind, divide three groups, 30 every group, the about 17.5 kilograms of every heads of body weight, the daily ration prescription is: corn 30%, barley 40%, wheat 18%, soya-bean cake 5%, dish cake 3%, oyster shell whiting 1%, fish meal 3%, per 100 jin of daily rations add 10 jin of left and right sides chaffs.

First control group is the formulated daily ration of above-mentioned raw materials, and wherein contained energy all conforms to the nutritional need of pig with various nutrients, raises after 130 days, and weight average is 80 kilograms, average daily gain 481 grams, and every kilogram of weightening finish consumption digestible energy is 52.5 million Jiao.

Second control group, consumption uses No. 3 additives in Taihu Lake in accordance with regulations.Weight average is 83.5 kilograms after 120 days, average daily gain 550 grams, every kilogram of weightening finish consumption digestible energy 47.39 million Jiao.

The 3rd test group, the general side that feeding the present invention was made into, the large, medium and small pig of consumption per day is respectively 30 grams, 25 grams, 15 grams, raises after 100 days, and weight average is 82.5 kilograms, daily gain 650 grams, every kilogram of weightening finish consumption digestible energy is 41.6 million Jiao.

More than each the group all adopt quantity-unlimiting feeding, free choice feeding, by a large number of experiments show that, test group all has preventive and therapeutic effect to various diseases.

It is as follows to draw feed prepared additive effect of the present invention by contrast:

(1), test group improves 35% than the first control group average daily gain.

(2), test group improves 18.2% than the second control group average daily gain.

(3), the carcass lean meat percentage of test group is than control group height.

Claims

1, a kind of Chinese herbal feed additive that is used for aquaculture is characterized in that it consists of: the Radix Astragali 150 grams, the bighead atractylodes rhizome 100 grams, Radix Codonopsis 120 grams, Radix Glycyrrhizae 60 grams, dried orange peel 120 grams, fushen's 150 grams, galangal 100 grams, cooked aconite 50 grams, HERBA EPIMEDII 150 grams, dark plum 100 grams, the fruit of Chinese magnoliavine 150 grams, Radix Angelicae Sinensis 150 grams, cultivated land 150 grams, hawthorn 500 grams, Fructus Hordei Germinatus 500 grams, concha meretricis seu cylinae 250 grams, the nine hole shells of seaear, 250 grams.

2, the preparation method of Chinese herbal feed additive as claimed in claim 1 is characterized in that: be with the above-mentioned medicine of respectively distinguishing the flavor of, be ground into fine powder according to the above ratio and obtain.