CN114903518A - An intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound - Google Patents
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Abstract
Description
技术领域technical field
本发明属于脊柱侧弯诊断和筛查技术领域,尤其涉及一种基于三维超声的智能化脊柱侧弯Cobb角测量方法。The invention belongs to the technical field of scoliosis diagnosis and screening, and in particular relates to an intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound.
背景技术Background technique
青少年特发性脊柱侧凸(Adolescent Idiopathic scoliosis,AIS)是一种致残性、致死性畸形,文献报道其发病率为2%~4%,好发于青春期的中小学生,主要表现为X线平片上脊柱侧凸Cobb角≥10°的脊柱三维结构异常。根据中华预防医学会流调数据,目前我国中小学生发生脊柱侧弯人数已经超过500万人,并以每年30万的速度递增。因此,对青少年特发性脊柱侧弯患者的及时筛查,精确评估和有效监测,可以帮助明确病情和采取适宜治疗措施防止病情恶化,从而减轻手术干预风险。Adolescent idiopathic scoliosis (AIS) is a disabling and fatal deformity, with an incidence of 2% to 4% reported in the literature. Abnormal three-dimensional structure of the spine with scoliosis Cobb angle ≥10° on plain radiographs. According to the data of the Chinese Preventive Medicine Association, the number of scoliosis cases in primary and secondary school students in my country has exceeded 5 million, and the number is increasing at a rate of 300,000 per year. Therefore, timely screening, accurate assessment and effective monitoring of adolescent idiopathic scoliosis patients can help to identify the disease and take appropriate treatment measures to prevent the disease from worsening, thereby reducing the risk of surgical intervention.
目前X线是诊断脊柱侧凸(脊柱侧弯)并跟踪其发展状态的最常用成像模式,但X线成像存在辐射伤害,而且二维X线图像难以全面反映三维畸形特征。脊柱侧弯Cobb角对于脊柱侧弯的诊断以及后续的治疗有着很重要的影响,而目前,对于Cobb角的测量,通常是采用获取X线片图像以后,经影像专家手动确立脊柱侧弯的上下端椎后,使用量角器量取出两终端之间夹角,但是这种方法使得患者受到X线的辐射,对患者会造成不同程度的伤害,而且,脊柱侧弯患者在后续治疗过程中,还需要多次拍X光片,因此,这种方法会对青少年患者造成较大的伤害。At present, X-ray is the most commonly used imaging modality for diagnosing scoliosis (scoliosis) and tracking its development status. However, X-ray imaging has radiation damage, and two-dimensional X-ray images cannot fully reflect the three-dimensional deformity characteristics. Scoliosis Cobb angle has a very important impact on the diagnosis and subsequent treatment of scoliosis. At present, for the measurement of Cobb angle, the X-ray image is usually obtained, and the upper and lower levels of scoliosis are manually established by imaging experts. After the end of the vertebra, use a protractor to measure the angle between the two ends, but this method exposes the patient to X-ray radiation, which will cause different degrees of damage to the patient, and scoliosis patients need to be treated in the follow-up process. Multiple X-rays are taken, so this method can cause greater harm to teenage patients.
发明内容SUMMARY OF THE INVENTION
为了解决现有技术中存在的问题,本发明的目的是提供一种基于三维超声的智能化脊柱侧弯Cobb角测量方法,本发明的Cobb角测量方法通过采用三维超声来采集患者的脊柱三维信息,并通过计算机进行分析后自动标记出Cobb角的两条相交线,进而测量出Cobb角。In order to solve the problems existing in the prior art, the purpose of the present invention is to provide an intelligent method for measuring the Cobb angle of scoliosis based on three-dimensional ultrasound. The method for measuring the Cobb angle of the present invention collects three-dimensional information of a patient's spine by using three-dimensional ultrasound. , and the two intersecting lines of the Cobb angle are automatically marked after analysis by the computer, and then the Cobb angle is measured.
为了实现上述发明目的,本发明采用如下所述的技术方案:In order to realize the above-mentioned purpose of the invention, the present invention adopts the following technical scheme:
一种基于三维超声的智能化脊柱侧弯Cobb角测量方法,包括以下步骤:An intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound, comprising the following steps:
S1、利用三维超声系统采集脊柱的三维超声图像信息,形成三维脊柱图像;S1. Use a three-dimensional ultrasound system to collect three-dimensional ultrasound image information of the spine to form a three-dimensional spine image;
S2、将步骤S1中获得的三维脊柱图像输入到计算机系统中,通过计算机系统对图像信息进行显示、处理和分析;S2, the three-dimensional spine image obtained in step S1 is input into the computer system, and the image information is displayed, processed and analyzed by the computer system;
S3、计算机系统对三维脊柱图像中的所有棘突进行识别提取,并生成对应的标记点,然后将所有标记点进行连线,形成棘突连线,棘突连线由上直线段、圆弧线段和下直线段构成,在上直线段与圆弧线段的过渡点处做圆弧线段的切线L1,在下直线段与圆弧线段的过渡点处做圆弧线段的切线L2,切线L1和切线L2形成的夹角α即为Cobb角。S3. The computer system identifies and extracts all the spinous processes in the three-dimensional spine image, generates corresponding marked points, and then connects all the marked points to form a spinous process connection line. The line segment and the lower straight line segment are formed. At the transition point of the upper straight line segment and the circular arc segment, the tangent L1 of the circular arc segment is made, and the tangent L2, tangent L1 and tangent of the circular arc segment are made at the transition point of the lower straight line segment and the circular arc segment. The included angle α formed by L2 is the Cobb angle.
进一步的,在步骤S3中,若棘突连线由上直线段、两段连续的圆弧线段和下直线段构成,则需要对两段圆弧线段分别测量Cobb角,即:将上下侧两段圆弧线段分别设为第一圆弧线段和第二圆弧线段,在上直线段与第一圆弧线段的过渡点处做圆弧线段的切线L1,在第一圆弧线段与第二圆弧线段的过渡点处做第一圆弧线段的切线L2,切线L1和切线L2形成的夹角α即为第一圆弧段的Cobb角,在第二圆弧线段与下直线段的过渡点处做第二圆弧线段的切线L3,切线L2和切线L3形成的夹角α即为第二圆弧段的Cobb角。Further, in step S3, if the connecting line of the spinous process consists of an upper straight line segment, two continuous arc line segments and a lower straight line segment, the Cobb angle needs to be measured separately for the two arc line segments, that is: The arc segment is set as the first arc segment and the second arc segment respectively, and the tangent L1 of the arc segment is made at the transition point between the upper straight line segment and the first arc segment, and the first arc segment and the second arc segment are set as the tangent L1 of the arc segment. The transition point of the arc segment is the tangent L2 of the first arc segment, and the angle α formed by the tangent L1 and the tangent L2 is the Cobb angle of the first arc segment, at the transition between the second arc segment and the lower straight segment The tangent L3 of the second arc segment is made at the point, and the angle α formed by the tangent L2 and the tangent L3 is the Cobb angle of the second arc segment.
进一步的,三维超声系统为多普勒超声诊断仪。Further, the three-dimensional ultrasound system is a Doppler ultrasound diagnostic apparatus.
进一步的,所述计算机系统配置有存储模块、显示模块、输出报告模块和处理器,存储模块用于储存三维脊柱图像信息以及Cobb角数据信息,处理器用于分析和处理三维超声图像信息,并通过显示模块进行显示,输出报告模块用于将经过处理器处理后的Cobb角数据信息以报告形式输出。Further, the computer system is configured with a storage module, a display module, an output report module and a processor, the storage module is used to store three-dimensional spine image information and Cobb angle data information, and the processor is used to analyze and process the three-dimensional ultrasound image information, and through The display module displays, and the output report module is used to output the Cobb angle data information processed by the processor in the form of a report.
由于采用上述技术方案,本发明具有以下有益效果:Owing to adopting the above-mentioned technical scheme, the present invention has the following beneficial effects:
1、本发明的Cobb角测量方法通过采用三维超声系统来采集患者的脊柱三维信息,只需要利用超声探头来扫描患者背部即可实现脊柱信息的采集,具有高效、安全的优点;1. The Cobb angle measurement method of the present invention collects the three-dimensional information of the patient's spine by using a three-dimensional ultrasound system, and only needs to use an ultrasound probe to scan the back of the patient to realize the acquisition of the spine information, which has the advantages of high efficiency and safety;
2、本发明对脊柱三位图像上面的棘突进行识别提取并生成棘突连线,在棘突连线上的弯曲部分两端分别对应画出切线,切线夹角即为Cobb角,采用本发明的测量方法测量出的Cobb角极为准确,而且适用性较强,只要有脊柱的三维超声影像即可通过计算机系统测量出Cobb角,进而判别是否存在脊柱畸形并评价其严重程度,最终给出风险报告及医疗建议。2. The present invention identifies and extracts the spinous processes on the three-dimensional images of the spine and generates a spinous process connection line. The two ends of the curved part of the spinous process connection line respectively draw tangent lines, and the angle between the tangent lines is the Cobb angle. The Cobb angle measured by the invented measurement method is extremely accurate and has strong applicability. As long as there is a three-dimensional ultrasound image of the spine, the Cobb angle can be measured by a computer system, and then the existence of spinal deformity can be judged and its severity can be evaluated. Risk reports and medical advice.
附图说明Description of drawings
图1为人体背面的棘突连线上单弯的Cobb角测量示意图;Fig. 1 is a schematic diagram of measuring the Cobb angle of a single bend on the connection line of the spinous process on the back of the human body;
图2为人体背面的棘突连线上双弯的Cobb角测量示意图;Figure 2 is a schematic diagram of the measurement of the Cobb angle of the double bends on the connection line of the spinous processes on the back of the human body;
图中:A:上直线段;B:下直线段;C:圆弧线段;C1:第一圆弧线段;C2:第二圆弧线段;D、U、S:过渡点;L1、L2:切线;L:棘突连线;α、α1、α2:Cobb角。In the figure: A: upper straight line segment; B: lower straight line segment; C: circular arc segment; C1: first circular arc segment; C2: second circular arc segment; D, U, S: transition point; L1, L2: Tangent line; L: line connecting the spinous processes; α, α1, α2: Cobb angle.
具体实施方式Detailed ways
下面结合附图及实施例对本发明的技术方案做进一步详细的说明。The technical solutions of the present invention will be described in further detail below with reference to the accompanying drawings and embodiments.
一种基于三维超声的智能化脊柱侧弯Cobb角测量方法,包括以下步骤:An intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound, comprising the following steps:
S1、利用三维超声系统采集脊柱的三维超声图像信息,形成三维脊柱图像;S1. Use a three-dimensional ultrasound system to collect three-dimensional ultrasound image information of the spine to form a three-dimensional spine image;
S2、将步骤S1中获得的三维脊柱图像输入到计算机系统中,通过计算机系统对图像信息进行显示、处理和分析;S2, the three-dimensional spine image obtained in step S1 is input into the computer system, and the image information is displayed, processed and analyzed by the computer system;
S3、计算机系统对三维脊柱图像中的所有棘突进行识别提取,并生成对应的标记点,然后将所有标记点进行连线,形成棘突连线L,如图1所示,棘突连线L由上直线段A、圆弧线段C和下直线段B构成,在上直线段A与圆弧线段C的过渡点U处做圆弧线段的切线L1,在下直线段B与圆弧线段C的过渡点D处做圆弧线段的切线L2,切线L1和切线L2形成的夹角α即为Cobb角。S3. The computer system identifies and extracts all the spinous processes in the three-dimensional spine image, generates corresponding marked points, and then connects all the marked points to form a spinous process connection line L, as shown in Figure 1, the spinous process connection line L consists of an upper straight line segment A, a circular arc line segment C and a lower straight line segment B. The tangent L1 of the circular arc segment is made at the transition point U of the upper straight line segment A and the circular arc line segment C, and the lower straight line segment B and the circular arc line segment C are formed. The tangent L2 of the arc segment is made at the transition point D of , and the angle α formed by the tangent L1 and the tangent L2 is the Cobb angle.
在步骤S3中,若棘突连线L由上直线段A、两段连续的圆弧线段和下直线段B构成,则需要对两段圆弧线段分别测量Cobb角,即:将上下侧两段圆弧线段分别设为第一圆弧线段C1和第二圆弧线段C2,在上直线段A与第一圆弧线段C1的过渡点U处做圆弧线段的切线L1,在第一圆弧线段C1与第二圆弧线段C2的过渡点D处做第一圆弧线段C1的切线L2,切线L1和切线L2形成的夹角α1即为第一圆弧段C1的Cobb角,在第二圆弧线段C2与下直线段B的过渡点S处做第二圆弧线段C2的切线L3,切线L2和切线L3形成的夹角α2即为第二圆弧段的Cobb角。In step S3, if the spinous process connecting line L is composed of an upper straight line segment A, two continuous arc line segments and a lower straight line segment B, it is necessary to measure the Cobb angle of the two arc line segments respectively, that is: The arc segment is set as the first arc segment C1 and the second arc segment C2 respectively, and the tangent L1 of the arc segment is made at the transition point U between the upper straight line segment A and the first arc segment C1, and the first arc segment is At the transition point D of the arc segment C1 and the second arc segment C2, the tangent L2 of the first arc segment C1 is made, and the angle α1 formed by the tangent L1 and the tangent L2 is the Cobb angle of the first arc segment C1. The tangent L3 of the second arc segment C2 is made at the transition point S between the two arc line segment C2 and the lower straight line segment B, and the angle α2 formed by the tangent line L2 and the tangent line L3 is the Cobb angle of the second arc segment.
在本发明中,所述的三维超声系统为多普勒超声诊断仪。In the present invention, the three-dimensional ultrasound system is a Doppler ultrasound diagnostic instrument.
所述计算机系统配置有存储模块、显示模块、输出报告模块和处理器,存储模块用于储存三维脊柱图像信息以及Cobb角数据信息,处理器用于分析和处理三维超声图像信息,并通过显示模块进行显示,输出报告模块用于将经过处理器处理后的Cobb角数据信息以报告形式输出。The computer system is configured with a storage module, a display module, an output report module and a processor, the storage module is used to store three-dimensional spine image information and Cobb angle data information, and the processor is used to analyze and process the three-dimensional ultrasound image information, and through the display module. Display, the output report module is used to output the Cobb angle data information processed by the processor in the form of a report.
在本发明的步骤S3中,正常人的棘突连线在人体背面看是一条直线,但是脊柱侧弯病人的棘突由于脊柱侧弯畸形,椎体会发生偏移或旋转,导致棘突位置发生改变,此时在人体背面看,棘突连线会形成一个弯曲(称为“单弯”),即单腰弯或单胸弯,或是在棘突连线上形成两个弯曲(称为“双弯”),即腰弯和胸弯,甚至棘突连线上会形成两个以上的弯曲,而弯曲部分即为需要测量的脊柱侧弯Cobb角所在位置。In step S3 of the present invention, the connection line of the spinous process of a normal person is a straight line when viewed from the back of the human body, but the spinous process of a patient with scoliosis due to scoliosis deformity, the vertebral body shifts or rotates, resulting in the position of the spinous process Changed, at this time, when viewed from the back of the human body, the line connecting the spinous processes will form a bend (called "single curve"), that is, a single lumbar or single thoracic curve, or two curves (called "single curve") are formed on the line connecting the spinous processes. "Double curvature"), that is, the lumbar and thoracic curvature, and even more than two curvatures will be formed on the connection of the spinous process, and the curved part is the location of the Cobb angle of scoliosis to be measured.
以单弯(即单腰弯或单胸弯)为例,测量脊柱侧弯Cobb角:Taking a single curve (i.e. a single lumbar or single thoracic curve) as an example, measure the Cobb angle of scoliosis:
如图1所示,棘突连线由上直线段、圆弧线段和下直线段构成,在上直线段与圆弧线段的过渡点处做圆弧线段的切线L1,在下直线段与圆弧线段的过渡点处做圆弧线段的切线L2,切线L1和切线L2形成的夹角α即为Cobb角。As shown in Figure 1, the connection line of the spinous process is composed of an upper straight line segment, a circular arc line segment and a lower straight line segment. The transition point of the line segment is the tangent L2 of the arc segment, and the angle α formed by the tangent L1 and the tangent L2 is the Cobb angle.
以双弯(即胸弯和腰弯)为例,测量脊柱侧弯Cobb角,如下所述:Taking double curves (i.e. thoracic and lumbar) as an example, measure the Cobb angle of scoliosis as follows:
由于是胸弯和腰弯双弯,那么棘突连线上存在两个圆弧线段,上面的圆弧线段为胸弯,下面的圆弧线段为腰弯,两个弯曲均为需要测量脊柱侧弯Cobb角的所在位置。Since it is a double curvature of the thoracic and lumbar curves, there are two arc segments on the connection between the spinous processes. The upper arc segment is the thoracic curve, and the lower arc segment is the lumbar curve. Both curves need to be measured on the side of the spine. The location of the curved Cobb angle.
如图2所示,棘突连线由上直线段、两段连续的圆弧线段和下直线段构成,则需要对两段圆弧线段分别测量Cobb角,即:将上下侧两段圆弧线段分别设为第一圆弧线段和第二圆弧线段,在上直线段与第一圆弧线段的过渡点处做圆弧线段的切线L1,在第一圆弧线段与第二圆弧线段的过渡点处做第一圆弧线段的切线L2,切线L1和切线L2形成的夹角α即为第一圆弧段的Cobb角,在第二圆弧线段与下直线段的过渡点处做第二圆弧线段的切线L3,切线L2和切线L3形成的夹角α即为第二圆弧段的Cobb角。As shown in Figure 2, the connecting line of the spinous process consists of an upper straight segment, two continuous arc segments and a lower straight segment, so the Cobb angle needs to be measured separately for the two arc segments, that is: The line segments are set as the first circular arc line segment and the second circular arc line segment respectively, and the tangent L1 of the circular arc line segment is made at the transition point between the upper straight line segment and the first circular arc line segment, and the first circular arc line segment and the second circular arc line segment. The tangent L2 of the first circular arc segment is made at the transition point of The angle α formed by the tangent L3 of the second circular arc segment, the tangent L2 and the tangent L3 is the Cobb angle of the second circular arc segment.
另外,需要说明的是,若棘突连线上存在两个以上的弯曲,则Cobb角的测量方法与上述双弯的测量方法相同,只需要将相邻圆弧线段过渡点处的切线做出即可得出Cobb角。In addition, it should be noted that if there are more than two bends on the connecting line of the spinous process, the measurement method of the Cobb angle is the same as the measurement method of the above-mentioned double bends. The Cobb angle can be obtained.
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| WO2023197924A1 (en) * | 2022-04-14 | 2023-10-19 | 深圳市第二人民医院(深圳市转化医学研究院) | Three-dimensional-ultrasound-based intelligent scoliosis cobb angle measuring method |
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| CN109965910A (en) * | 2019-04-12 | 2019-07-05 | 东南大学 | A sagittal projection imaging method based on three-dimensional ultrasound spine volume data |
| CN110458831A (en) * | 2019-08-12 | 2019-11-15 | 深圳市智影医疗科技有限公司 | A kind of scoliosis image processing method based on deep learning |
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| CN114299015A (en) * | 2021-12-28 | 2022-04-08 | 上海联影智融医疗科技有限公司 | Method and device for determining scoliosis angle |
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| JP2019520954A (en) * | 2016-04-25 | 2019-07-25 | 中慧医学成像有限公司 | Method and device for measuring the angle of curvature of the spine |
| CN106725500A (en) * | 2017-01-17 | 2017-05-31 | 上海脊光医疗科技有限公司 | Functional spinal measurement apparatus |
| CN109223032B (en) * | 2017-07-11 | 2022-02-08 | 中慧医学成像有限公司 | A method for detecting spine deformation by three-dimensional ultrasound imaging |
| CN107595387B (en) * | 2017-07-28 | 2020-08-07 | 浙江大学 | A spine image generation system and spine surgery navigation and positioning system based on ultrasonic rubbing technology |
| CN113537408B (en) * | 2021-09-08 | 2025-01-28 | 深圳开立生物医疗科技股份有限公司 | Ultrasonic image processing method, device, equipment and storage medium |
| CN114081471B (en) * | 2021-11-11 | 2024-02-09 | 宜宾显微智能科技有限公司 | Scoliosis cobb angle measuring method based on three-dimensional image and multilayer perception |
| CN114903518A (en) * | 2022-04-14 | 2022-08-16 | 深圳市第二人民医院(深圳市转化医学研究院) | An intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound |
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| CN109965910A (en) * | 2019-04-12 | 2019-07-05 | 东南大学 | A sagittal projection imaging method based on three-dimensional ultrasound spine volume data |
| CN110458831A (en) * | 2019-08-12 | 2019-11-15 | 深圳市智影医疗科技有限公司 | A kind of scoliosis image processing method based on deep learning |
| CN112734757A (en) * | 2021-03-29 | 2021-04-30 | 成都成电金盘健康数据技术有限公司 | Spine X-ray image cobb angle measuring method |
| CN114299015A (en) * | 2021-12-28 | 2022-04-08 | 上海联影智融医疗科技有限公司 | Method and device for determining scoliosis angle |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2023197924A1 (en) * | 2022-04-14 | 2023-10-19 | 深圳市第二人民医院(深圳市转化医学研究院) | Three-dimensional-ultrasound-based intelligent scoliosis cobb angle measuring method |
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