CN114570597B - Coating auxiliary device and coating method for dense net support - Google Patents

Abstract

The invention discloses a coating auxiliary device and a coating method of a dense net support, wherein the coating auxiliary device comprises an outer layer sheet, an outer gasket, an inner gasket and an inner layer sheet; wherein, the outer layer sheet is arranged on the outer side wall of the dense net support, and the middle part of the outer layer sheet horizontally extends towards one side of the dense net support to form an expansion part; the inner layer sheet is arranged on the inner side wall of the dense net support, and an expansion hole is formed in the middle of the inner layer sheet; the outer gasket is arranged on one side of the outer ply close to the dense net support; the inner gasket is arranged on one side of the inner ply close to the dense net bracket; one end of the expansion part far away from the outer ply sequentially passes through the outer gasket, the dense net support and the inner gasket and then is inserted into the expansion part Kong Zhang for tightening, so that the outer ply, the outer gasket, the inner gasket and the inner ply are tightly attached to the dense net support.

Description

Coating auxiliary device and coating method for dense mesh support

technical field

The invention relates to the technical field of medical devices, in particular to a coating auxiliary device and a coating method for a dense mesh stent.

Background technique

Aneurysm is a manifestation of localized or diffuse dilation or bulging of the arterial wall due to lesion or injury of the arterial wall. At present, the commonly used clinical method for treating aneurysms is to install a dense-mesh stent in the human body, and use the dense-mesh stent to direct blood flow.

The dense mesh support has a pipe network structure as shown in Figure 1 as a whole, and the dense mesh support needs to be selectively coated on the surface of the dense mesh support before use, while the coating device of the dense mesh support in the prior art, It is mainly aimed at the overall and complete coating of the dense mesh stent, and cannot effectively selectively coat the surface of the dense mesh stent.

Contents of the invention

The present invention aims to solve at least one of the technical problems existing in the prior art.

For this reason, the present invention proposes a coating auxiliary device and a coating method for a dense-mesh stent, which can effectively and selectively coat the surface of the dense-mesh stent.

According to the first aspect of the present application, there is provided a coating auxiliary device for a dense mesh stent, comprising: an outer layer sheet, an outer gasket, an inner gasket, and an inner layer sheet;

The outer layer sheet is installed on the outer wall of the dense mesh support, and the middle part of the outer layer sheet extends horizontally toward one side of the dense mesh support with an expansion part;

The inner layer sheet is installed on the inner side wall of the dense mesh support, and the middle part of the inner layer sheet is provided with a tightening hole;

The outer gasket is installed on the side of the outer sheet close to the dense mesh support;

The inner gasket is installed on the side of the inner sheet close to the dense mesh support;

Wherein, the end of the expansion part away from the outer sheet passes through the outer gasket, the dense mesh support and the inner gasket in turn, and then is inserted into the expansion hole to expand and tighten the outer layer. The sheet, the outer gasket, the inner gasket and the inner sheet are all in close contact with the dense mesh support.

In the above device, the outer layer sheet is configured as a curved surface structure matching the shape of the outer wall of the dense mesh support, so that the outer layer sheet is closely attached to the outer wall of the dense mesh support.

In the above device, the inner layer sheet is configured as a curved surface structure matching the shape of the inner side wall of the dense mesh support, so that the inner layer sheet is closely attached to the inner side wall of the dense mesh support.

In the above device, both the outer layer sheet and the inner layer sheet have plasticity.

In the above device, the middle part of the outer gasket is provided with a first via hole for the end of the expansion part away from the outer sheet to pass through, and the middle part of the inner gasket is provided with a hole for the expansion part to go away from. A second via hole through which one end of the outer sheet passes.

In the above device, both the outer gasket and the inner gasket are waterproof gaskets.

In the above device, the expansion part has a cylindrical structure, and an abutment part radially extends from one end of the expansion part away from the outer sheet.

According to the second aspect of the present application, there is provided a method for coating a dense mesh stent, using the above-mentioned coating auxiliary device, the method includes the following steps:

S110, pre-configuring the coating solution in the container, and standing for 24 hours;

S120. Install the coating auxiliary device on the part of the dense mesh support that does not need to be coated;

S130. Place the dense mesh support in a container, and completely immerse the dense mesh support in the coating solution;

S140, immersing the dense mesh support in the coating solution for 3 minutes to 5 minutes and then taking it out;

S150, blowing air on the dense mesh support to dry the coating solution on the dense mesh support;

S160. After the coating solution on the dense mesh support is completely dried, remove the coating auxiliary device from the dense mesh support.

In the above method, the raw materials for preparing the coating solution include absolute ethanol and polyphosphorylcholine.

In the above method, the polyphosphorylcholine is in powder form, the weight of the polyphosphorylcholine is 1g to 2g, and the volume of the dehydrated alcohol is 100ml; the polyphosphorylcholine is added to In the dehydrated ethanol, the polyphosphorylcholine is completely dissolved in the dehydrated ethanol by stirring in a centrifuge to form the coating solution.

According to the technical solution provided by this application, it has at least the following beneficial effects: the coating auxiliary device is installed on the part that does not need to be coated on the dense mesh support, and after the coating solution on the dense mesh support is completely dried, the coated The layer aid is removed from the dense mesh support, and it can be observed that the position where the coating aid is installed is not coated. With the dense mesh stent coated by the above-mentioned coating auxiliary device and coating method, the uncoated part can be effectively positioned at the neck of the aneurysm, ensuring that the neck of the aneurysm is preferentially endothelialized.

Additional features and advantages of the application will be set forth in the description which follows, and, in part, will be obvious from the description, or may be learned by practice of the application. The objectives and other advantages of the application will be realized and attained by the structure particularly pointed out in the written description and claims hereof as well as the appended drawings.

Description of drawings

The above and/or additional aspects and advantages of the present invention will become apparent and understandable from the description of the embodiments in conjunction with the following drawings, wherein:

Fig. 1 is the structural representation of dense mesh support;

Fig. 2 is a cross-sectional view of the installation structure of the coating auxiliary device provided by the embodiment of the present application;

Fig. 3 is a schematic structural view of the outer layer sheet provided by the embodiment of the present application;

Figure 4 is a schematic structural view of the inner sheet provided by the embodiment of the present application;

Figure 5 is a cross-sectional view of a coated stent provided in an embodiment of the present application;

Figure 6 is a cross-sectional view of a top cover provided by an embodiment of the present application;

Figure 7 is a schematic structural view of the coating system provided by the embodiment of the present application;

Fig. 8 is a coating effect diagram of a dense mesh bracket utilizing a coating auxiliary device;

Fig. 9 is an effect diagram of the positioning of the dense mesh stent in Fig. 8 at the neck of the aneurysm;

Fig. 10 is an effect diagram of the release of the dense mesh stent along the vessel wall.

Reference signs:

Coating auxiliary device 100, outer layer sheet 110, expansion part 111, contact part 112, outer gasket 120, inner gasket 130, inner layer sheet 140, expansion hole 141;

Coating bracket 200, base 210, support column 220, first external thread 221, third external thread 222, support bar 230, top cover 240, through hole 242, bolt 243, connecting column 250, second external thread 251;

dense mesh support 300;

Workbench 400, gantry frame 410, slide rail 420, slider 430;

container 500;

Air nozzle 600;

Driving device 700, first cylinder 710, second cylinder 720, motor 730, coupling 740;

Detailed ways

In order to make the purpose, technical solution and advantages of the present application clearer, the present application will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present application, not to limit the present application.

It should be noted that although the functional modules are divided in the schematic diagram of the device, and the logical sequence is shown in the flowchart, in some cases, it can be executed in a different order than the module division in the device or the flowchart in the flowchart. steps shown or described. The terms "first", "second" and the like in the specification and claims and the above drawings are used to distinguish similar objects, rather than to describe a specific sequence or sequence.

In relation to orientation descriptions, the terms "center, longitudinal, transverse, length, width, thickness, up, down, front, back, left, right, vertical, horizontal, top, bottom, inner, outer, circumferential, radial, The orientation or positional relationship indicated by "axial" and the like are based on the orientation or positional relationship shown in the drawings, which are only for the convenience of describing the application and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, constructed and operated in a particular orientation and therefore should not be construed as limiting the application. Several means one or more, and multiple means more than two. Greater than, less than, exceeding, etc. are understood as not including the original number, and above, below, within, etc. are understood as including the original number.

Unless otherwise expressly specified and limited, the terms "mounted", "connected", "connected", "set", "arranged", etc. shall be interpreted in a broad sense, for example, may be a fixed connection or a detachable connection, or Integral connection; it can be mechanical connection or electrical connection; it can be direct connection, or indirect connection through an intermediary or an intermediate connector, and it can be the internal communication of two components. Those of ordinary skill in the art can understand the specific meanings of the above terms in this application in specific situations.

In order to make the purpose, technical solution and advantages of the present application clearer, the implementation manners of the present application will be further described in detail below in conjunction with the accompanying drawings.

As shown in Fig. 2, Fig. 3 and Fig. 4, the embodiment of the first aspect of the present application provides a coating auxiliary device 100 of a dense mesh support, and the coating auxiliary device 100 can be installed on the surface of the dense mesh support 300. The area that needs to be coated to avoid the area being coated.

The coating aid 100 includes an outer sheet 110 , an outer gasket 120 , an inner gasket 130 and an inner sheet 140 . Wherein, the outer layer sheet 110 is installed on the outer wall of the dense mesh support 300, and the middle part of the outer layer sheet 110 extends horizontally toward one side of the dense mesh support 300 to have an expansion part 111, and the expansion part 111 has a columnar structure and has elasticity; In this application, the expansion part 111 and the outer layer sheet 110 can be integrally formed, or can be made into parts separately, and then installed together, but the sealing between the expansion part 111 and the outer layer sheet 110 must be ensured.

The inner layer sheet 140 is installed on the inner side wall of the dense mesh support 300, and the middle part of the inner layer sheet 140 is provided with an expansion hole 141; the outer gasket 120 is installed on the side of the outer layer sheet 110 close to the dense mesh support 300; the inner gasket 130 Installed on the side of the inner layer sheet 140 close to the dense mesh bracket 300; the end of the expansion part 111 away from the outer layer sheet 110 passes through the outer gasket 120, the dense mesh bracket 300 and the inner gasket 130 in sequence, and then inserts into the expansion hole 141 for expansion so that the outer layer sheet 110, outer gasket 120, inner gasket 130 and inner layer sheet 140 are all tightly attached to the dense mesh support 300, so as to prevent the coating solution from infiltrating into the parts of the dense mesh support 300 that do not need to be coated.

In some specific embodiments of the present application, in order to further ensure that the outer layer sheet 110, the outer gasket 120, the inner gasket 130 and the inner layer sheet 140 are tightly attached to the dense mesh support 300, the expansion part 111 is far away from one end diameter of the outer layer sheet 110. An abutting portion 112 extends in the direction. The abutment portion 112 abuts against the side of the inner layer sheet 140 away from the dense mesh support 300 to prevent loosening between the outer layer sheet 110, the outer gasket 120, the inner gasket 130 and the inner layer sheet 140, and prevent the coating solution from immersing The gap between the outer layer sheet 110 , the outer gasket 120 , the inner gasket 130 and the inner layer sheet 140 .

In some specific embodiments of the present application, as shown in FIG. 2 and FIG. 3 , in order to enable the outer sheet 110 to be close to the outer side wall of the dense mesh support 300, the overall shape of the outer layer sheet 110 is set to be consistent with the dense mesh support. The shape of the outer side wall of 300 matches the curved surface structure; and the material of the outer layer sheet 110 has plasticity.

In some specific embodiments of the present application, as shown in Fig. 2 and Fig. 4, in order to make the inner layer sheet 140 close to the inner side wall of the dense mesh support 300, the overall shape of the inner layer sheet 140 is set to be consistent with the dense mesh support The shape of the inner wall of 300 matches the curved surface structure; and the material of the inner layer sheet 140 has plasticity.

In some specific embodiments of the present application, the middle part of the outer gasket 120 is provided with a first via hole (not shown) for the end of the expansion part 111 away from the outer sheet 110 to pass through; the middle part of the inner gasket 130 A second via hole (not shown in the figure) is opened for the end of the expansion part 111 away from the outer sheet 110 to pass through.

In some specific embodiments of the present application, both the outer gasket 120 and the inner gasket 130 are waterproof gaskets. The outer gasket 120 and the inner gasket 130 can be made of soft polymer materials such as silica gel and silicone rubber, which are elastic. In this application, the material of the outer gasket 120 and the inner gasket 130 is preferably silicon rubber. When the outer layer sheet 110, the outer gasket 120, the inner gasket 130 and the inner layer sheet 140 are close to the dense mesh support 300, the outer gasket 120 and the inner gasket 130 can also play a sealing effect to prevent the coating solution from infiltrating into the outer layer. In the gap between the layer sheet 110 , the outer gasket 120 , the inner gasket 130 and the inner layer sheet 140 .

In some specific embodiments of the present application, the expanded shape of the outer gasket 120 matches the expanded shape of the outer layer sheet 110; the expanded shape of the inner gasket 130 matches the expanded shape of the inner layer sheet 140, so as to further Prevent the coating solution from infiltrating into the parts of the dense mesh support 300 that do not need to be coated.

Using the above-mentioned auxiliary coating device, in actual application, the dimensions of the outer layer sheet 110, the outer gasket 120, the inner gasket 130 and the inner layer sheet 140 can be made according to the size of the actual aneurysm. The position corresponding to the aneurysm on the dense mesh stent 300 is not coated, and the remaining positions are coated; the uncoated position is placed in the aneurysm to treat the aneurysm, and the coated position is placed in the blood vessel without an aneurysm to prevent occlusion Blood vessel.

In practical application, the outer layer sheet 110 , the outer gasket 120 , the inner gasket 130 and the inner layer sheet 140 can also be made into a general-purpose cylindrical structure, which is set in the middle of the dense mesh support 300 . The middle part of the dense mesh stent 300 is not coated, and the remaining positions are coated; in this way, there is no need to make the outer layer sheet 110, the outer gasket 120, the inner gasket 130 and the inner layer sheet 140 according to the size of the actual aneurysm, which is beneficial to reduce the outer layer It is difficult to manufacture the sheet 110, the outer gasket 120, the inner gasket 130 and the inner layer sheet 140.

The embodiment of the second aspect of the present application provides a method for coating a dense mesh stent, using the above-mentioned coating auxiliary device, the method includes the following steps:

S110, pre-configuring the coating solution in the container, and standing for 24 hours;

S120, installing a coating auxiliary device on the part of the dense mesh support that does not need to be coated;

S130, placing the dense mesh support in the container, and completely immersing the dense mesh support in the coating solution;

S140, immersing the dense mesh support in the coating solution for 3 minutes to 5 minutes and then taking it out;

S150, blowing air on the dense mesh support to dry the coating solution on the dense mesh support;

S160. After the coating solution on the dense mesh support is completely dried, the coating auxiliary device is removed from the dense mesh support.

In some specific embodiments of the present application, the raw materials for preparing the coating solution include absolute ethanol and polyphosphorylcholine.

Further, polyphosphorylcholine is in powder form, the weight of polyphosphorylcholine is 1g-2g, and the volume of absolute ethanol is 100ml; in this application, the weight of polyphosphorylcholine is preferably 1.5g.

Further, the polyphosphorylcholine is added into the absolute ethanol, and stirred by a centrifuge to completely dissolve the polyphosphorylcholine in the absolute ethanol to form a coating solution. Using this coating solution, the formation of platelets can be effectively inhibited.

In the present application, polyphosphorylcholine can be combined with the metal surface of the dense mesh stent 300 by forming a covalent bond, which can effectively ensure the firmness of the surface coating of the dense mesh stent 300 and prevent the coating from falling off.

Using the above-mentioned coating auxiliary device and coating method, install the coating auxiliary device on the part that does not need to be coated on the dense mesh support, and after the coating solution on the dense mesh support is completely dried, remove the coating auxiliary device from the Removed from the dense mesh bracket, it can be observed that the position where the coating auxiliary device is installed is not coated. With the dense mesh stent coated by the above-mentioned coating auxiliary device and coating method, the uncoated part can be effectively positioned at the neck of the aneurysm, ensuring that the neck of the aneurysm is preferentially endothelialized.

As shown in FIG. 5 , the embodiment of the third aspect of the present application provides a coated stent 200 for a dense mesh stent. The coating bracket 200 includes a base 210 , a supporting column 220 , a top cover 240 and a plurality of connecting columns 250 .

Wherein, the base 210 and the top cover 240 are arranged parallel and horizontally, and the top cover 240 is arranged on the top of the base 210; It is detachably connected with the middle part of the top cover 240 , and the support column 220 is used for installing the dense mesh bracket 300 . Specifically, the dense mesh bracket 300 is sleeved on the outside of the support column 220 .

A plurality of connection columns 250 are arranged parallel and vertically around the support column 220, and the minimum distance between each connection column 250 and the support column 220 is greater than the outer diameter of the dense mesh support 300, so as to prevent the dense mesh support 300 from contacting the connection column 250 Collision. The lower end of each connecting post 250 is detachably connected to the base 210 , and the upper end of each connecting post 250 is detachably connected to the top cover 240 . It should be noted that, when the coated stent 200 rotates in the coating solution, the connecting column 250 can break down the eddy current, preventing the vortex flow from torsionally deforming the dense mesh stent 300 and further damaging the dense mesh stent 300 .

In some specific embodiments of the present application, the lower part of the supporting column 220 is provided with a first external thread 221 in the circumferential direction, and the middle part of the base 210 is provided with a first internal thread matching the first external thread 221. The lower part of the supporting column 220 is connected with the The base 210 is detachably connected by threads.

In some specific embodiments of the present application, the connecting column 250 has a hollow cavity structure; the outer wall of the lower end of the connecting column 250 is provided with a second external thread 251 in the circumferential direction, and the corresponding position on the base 210 is provided with a second external thread 251 . The thread 251 matches the second internal thread, and the lower end of the connecting column 250 is detachably connected to the base 210 through the thread. In one embodiment, as shown in FIG. 6 , the middle part of the top cover 240 is provided with a through hole 242 for the upper part of the support column 220 to pass through; A third internal thread (not shown in the figure) cooperating with the bolt 243 is opened in the circumferential direction. After the upper end of the supporting column 220 passes through the through hole 242 , the top cover 240 is detachably connected to the upper end of the connecting column 250 through the bolt 243 . In another embodiment, a third external thread 222 is formed on the upper circumference of the supporting column 220 , and a fourth internal thread matching the third external thread 222 is formed on the middle of the top cover 240 . The upper part of the support column 220 is detachably connected to the top cover 240 through threads. After the support column 220 is connected to the top cover 240 , the top cover 240 and the upper end of the connection column 250 can be abutted against each other.

In some specific embodiments of the present application, a support bar 230 for supporting the dense mesh support 300 extends horizontally outward from the lower part of the support column 220 along its radial direction. The mesh support 300 is sleeved on the outside of the support column 220 , and the bottom of the dense mesh support 300 abuts against the upper end of the support bar 230 . In this application, one support bar 230 is provided in a slender strip structure; such an arrangement is beneficial to reduce the contact area between the support bar 230 and the dense mesh support 300 , so that the surface of the dense mesh support 300 can be fully coated. When the coating bracket 200 rotates in the coating solution, the support bar 230 can support the dense mesh bracket 300 without affecting the coating effect of the dense mesh bracket 300, so as to avoid the direct contact between the dense mesh bracket 300 and the base 210 to cause collision Bending is beneficial to protect the dense mesh bracket 300 .

Further, the length of the support bar 230 is greater than the outer diameter of the dense mesh bracket 300 and smaller than the minimum distance between the connecting column 250 and the supporting column 220 , so as to avoid contact between the supporting bar 230 and the connecting column 250 .

As shown in Figure 7, the embodiment of the fourth aspect of the present application provides a coating system for a dense mesh support, including a workbench 400, a controller (not shown in the figure), a container 500, a plurality of air nozzles 600, The driving device 700 and the coating auxiliary device 100 provided in the embodiment of the first aspect above and the coating support 200 provided in the embodiment of the third aspect above. Wherein, the container 500 is placed on the workbench 400, and the container 500 is used to hold the coating solution to coat the dense mesh support 300; a plurality of air nozzles 600 are arranged on the top of the workbench 400, and the plurality of air nozzles 600 use Carry out air jet drying to the dense mesh support 300 after coating; Driving device 700 is connected with coating support 200, is used to drive coating support 200 to move relative to container 500; Driving device 700 and a plurality of air nozzles 600 are all electrically connected to control device.

In this application, after the coating auxiliary device 100 is installed on the part of the dense mesh support 300 that does not need to be coated, the dense mesh support 300 is installed on the coating support 200, and the controller first controls the driving device 700 to drive the coating support 200 to move. to the container 500; after the dense mesh support 300 is completely submerged in the coating solution, the controller controls the driving device 700 to drive the coating support 200 to rotate, so that the dense mesh support 300 performs rotating coating. By adopting the rotating coating method, the coating solution can be effectively and evenly applied to the parts of the dense mesh support 300 that need to be coated, thereby ensuring that the parts of the dense mesh support 300 that need to be coated are evenly applied and the coating is prevented from falling off.

After the dense mesh support 300 is fully coated, the controller controls the driving device 700 to drive the coating support 200 to move away from the container 500 towards the position of the air nozzle 600; when the coating support 200 moves to the area surrounded by a plurality of air nozzles 600, The controller controls multiple air nozzles 600 to spray air to the dense mesh support 300 at the same time to dry the coating solution on the dense mesh support 300 . In the present application, a plurality of air nozzles 600 are arranged around, and when the coating support 200 moves to the area surrounded by the plurality of air nozzles 600, the plurality of air nozzles 600 simultaneously spray air on the dense mesh support 300 from different directions to fully dry The coating solution on the dense mesh support 300 further ensures the uniformity of the coating on the dense mesh support 300 .

In some specific embodiments of the present application, a gantry 410 is arranged on the workbench 400; the driving device 700 includes a first cylinder 710, a second cylinder 720 and a motor 730; the body of the first cylinder 710 and the body of the second cylinder 720 The cylinder body is installed on the beam of the gantry 410; the piston rod of the first cylinder 710 is connected with the cylinder body of the second cylinder 720; the piston rod of the second cylinder 720 is vertically arranged and connected with the body of the motor 730; the main shaft of the motor 730 The coating support 200 is connected through a coupling 740; the first cylinder 710, the second cylinder 720 and the motor 730 are all electrically connected to the controller. Specifically, the main shaft of the motor 730 is connected to the upper end of the support column 220 in the coating bracket through a coupling 740 .

In this application, after the dense mesh support 300 is installed on the coating support 200, the controller first controls the first cylinder 710 to drive the coating support to move above the container 500; the controller controls the second cylinder 720 to drive the coating support 200 to Move down until the dense mesh support 300 is completely submerged in the coating solution; the controller controls the control motor 730 to drive the coating support 200 to rotate in the coating solution at a predetermined speed, so that the dense mesh support 300 is rotated and coated. It should be noted that during the rotation of the coating bracket 200 in the coating solution, a vortex flow will be generated, and the connecting column 250 in the coating bracket 200 can have the effect of decomposing the vortex flow, and can effectively prevent the vortex flow from making the dense mesh The bracket 300 is torsionally deformed, thereby avoiding damage to the dense mesh bracket 300 .

After the dense mesh support 300 is fully coated, the controller controls the second cylinder 720 to drive the coating support 200 to move upwards away from the container 500; the controller controls the first cylinder 710 to drive the coating support 200 to move toward the position of the air nozzle 600, At the same time, under the cooperation of the second air cylinder 720, the coating support 200 is moved to the area surrounded by a plurality of air nozzles 600; layer solution; after the coating solution on the dense mesh stent 300 is fully dried, the dense mesh stent 300 is taken out from the coating stent.

In some specific embodiments of the present application, the beam of the gantry 410 is provided with a slide rail 420 along the length direction of the beam, and the side of the cylinder body of the second cylinder 720 facing the slide rail 420 is provided with a sliding rail that cooperates with the slide rail 420. Slider 430 .

In some specific embodiments of the present application, each air nozzle 600 is provided with a valve (not shown in the figure), and the valve is electrically connected to the controller.

The embodiment of the fifth aspect of the present application also provides a method for coating a dense mesh stent, using the above-mentioned coating system, the method includes the following steps:

S210, pre-configuring the coating solution in the container, and standing for 24 hours;

S220, installing a coating auxiliary device on the part of the dense mesh support that does not need to be coated;

S230, installing the dense mesh support on the coating support;

S240, connecting the coating bracket with the driving device;

S250. The controller controls the drive device to drive the coating support to move towards the container, and completely immerse the dense mesh support in the coating solution;

S260. The controller controls the driving device to drive the coating bracket to rotate in the coating solution for 3 to 5 minutes, and then take out the coating bracket;

S270. When the controller controls the driving device to move the coating support to the area surrounded by multiple air nozzles, the controller opens the valves of the multiple air nozzles, so that the multiple air nozzles simultaneously blow air to the dense mesh support from different directions to Dry the coating solution on the dense mesh support;

S280. After the coating solution on the dense-mesh stent is completely dried, take the dense-mesh stent out of the coating stent.

S290, removing the coating auxiliary device from the dense mesh support.

The preparation method of the coating solution is the same as above, and will not be repeated here.

In other embodiments of the present application, the coating solution may also be directly sprayed on the dense mesh support 300 by using nozzles.

Figure 8 is the effect diagram of the dense mesh bracket being coated with the coating auxiliary device; it can be seen from Figure 8 that the part of the dense mesh bracket where the coating auxiliary device is installed is not coated, and the coating auxiliary device is not installed parts are evenly coated.

Figure 9 is an effect diagram of the positioning of the partially coated dense mesh stent at the neck of the aneurysm; it can be seen from Figure 9 that the uncoated part of the dense mesh stent can be positioned at the neck of the aneurysm To achieve effective positioning, to ensure the preferential formation of endothelialization at the neck of the aneurysm.

Figure 10 is the effect diagram of the release of the dense mesh stent along the vessel wall; it can be seen from Figure 10 that the uncoated dense mesh stent gathers at the neck of the aneurysm to ensure the preferential formation of the neck of the aneurysm Endothelialization; a coated dense-mesh stent is distributed along the vessel wall to prevent occlusion of the vessel.

The above is a specific description of the preferred implementation of the present application, but the present application is not limited to the above-mentioned implementation, and those skilled in the art can also make various equivalent deformations or replacements without violating the spirit of the present application. These equivalent modifications or replacements are all within the scope defined by the claims of the present application.

Claims (9)

1. A coating assist device for a dense mesh stent, comprising: an outer ply, an outer gasket, an inner gasket and an inner ply;

the outer layer sheet is arranged on the outer side wall of the dense net support, and an expansion part horizontally extends from the middle part of the outer layer sheet towards one side of the dense net support;

the inner layer sheet is arranged on the inner side wall of the dense net support, and an expansion hole is formed in the middle of the inner layer sheet;

the outer gasket is arranged on one side of the outer layer sheet, which is close to the dense net support;

the inner gasket is arranged on one side of the inner layer sheet, which is close to the dense net support;

wherein the outer gasket and the inner gasket are waterproof gaskets; the expansion part sequentially penetrates through the outer gasket, the dense net support and the inner gasket and then is inserted into the expansion part Kong Zhang to be tightly pressed, so that the outer layer sheet, the outer gasket, the inner gasket and the inner layer sheet are tightly attached to the part, which is not required to be coated, of the surface of the dense net support, and the part is prevented from being coated.

2. The coating assist device of claim 1 wherein the outer sheet is configured in a curved configuration that matches the shape of the outer side wall of the dense mesh support such that the outer sheet is in close proximity to the outer side wall of the dense mesh support.

3. The coating assist device of claim 1 wherein the inner sheet is configured to have a curved configuration that matches the shape of the inner side wall of the dense mesh support such that the inner sheet is in close proximity to the inner side wall of the dense mesh support.

4. The coating assist device of claim 1 wherein the outer ply and the inner ply each have plasticity.

5. The coating assist device of claim 1 wherein a first via is provided in a middle portion of the outer shim through which an end of the expansion portion remote from the outer ply passes, and a second via is provided in a middle portion of the inner shim through which an end of the expansion portion remote from the outer ply passes.

6. The coating assist device of claim 1 wherein the expansion has a cylindrical configuration, and wherein an end of the expansion remote from the outer ply has an abutment extending radially therefrom.

7. A method of coating a dense mesh stent, characterized in that a coating aid as claimed in claims 1 to 6 is used, the method comprising the steps of:

s110, preparing a coating solution in a container in advance, and standing for 24 hours;

s120, installing the coating auxiliary device on a part of the dense net support, which does not need a coating;

s130, placing the dense mesh support in a container, and completely immersing the dense mesh support in the coating solution;

s140, immersing the dense net bracket in the coating solution for 3-5 minutes, and then taking out;

s150, blowing the dense net support to dry the coating solution on the dense net support;

and S160, after the coating solution on the dense net support is completely dried, removing the coating auxiliary device from the dense net support.

8. The coating method according to claim 7, wherein the raw materials for preparing the coating solution include anhydrous ethanol and polyphosphoryl choline.

9. The coating method according to claim 8, wherein the polyphosphorylcholine is in the form of powder, the weight of the polyphosphorylcholine is 1 g-2 g, and the volume of the absolute ethyl alcohol is 100ml; adding the polyphosphoryl choline into the absolute ethanol, and stirring by a centrifugal machine to completely dissolve the polyphosphoryl choline in the absolute ethanol to form the coating solution.

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