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CN1143308A - Food for preventing occurrence of diseases and its preparation method - Google Patents

Food for preventing occurrence of diseases and its preparation method Download PDF

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CN1143308A
CN1143308A CN94195043A CN94195043A CN1143308A CN 1143308 A CN1143308 A CN 1143308A CN 94195043 A CN94195043 A CN 94195043A CN 94195043 A CN94195043 A CN 94195043A CN 1143308 A CN1143308 A CN 1143308A
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deuterium
water
food
deuterium content
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加伯·索姆利埃
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HYD KUTATO-FEJLESZTO KTF
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Abstract

本发明涉及预防疾病的食品的生产方法,其中,采用标准的电解法和/或蒸馏法将水中的氘含量降低到111-135ppm,并用这样制得的水作为藻类生产的营养液,或用来浇灌用于食品工业中的植物,从而得到氘含量较低的藻类和植物,或将氘含量为111-135ppm的水用于生产软饮料和啤酒。The present invention relates to a method for producing food for preventing diseases, wherein the deuterium content in water is reduced to 111-135 ppm by standard electrolysis and/or distillation, and the water thus obtained is used as a nutrient solution for algae production or for watering plants used in the food industry, thereby obtaining algae and plants with a lower deuterium content, or water with a deuterium content of 111-135 ppm is used for the production of soft drinks and beer.

Description

预防疾病发生的食品及其制备方法Food for preventing occurrence of diseases and its preparation method

本发明涉及预防疾病发生的食品。此外,本发明还涉及制备这些产品的方法。The present invention relates to food for preventing the occurrence of diseases. Furthermore, the invention also relates to processes for the preparation of these products.

众所周知,从胚胎产生之时直到人体死亡之日,在人的机体中会发生1016次细胞分裂。细胞分裂是由于遗传信息,DNA,成倍增加而进行的。担负DNA合成的酶,以10-6的概率复制一个有缺陷的密码,从而产生与原基因不同的基因(突变体)。在大多数情况下,这种“错误”对细胞不会产生任何问题。然而,当这些突变发生在某些对调节细胞分裂起重要作用的基因的部位时,由于遗传信息的改变,迅即发生有缺陷的细胞再成倍地增加,且这一过程继续进行,从而产生一群比邻近细胞生长得更快的细胞。如果机体不能及时识别这些快速增殖的细胞,该过程就会导致恶性肿瘤的产生。It is well known that 1016 cell divisions will occur in the human body from the time the embryo is born until the day of death. Cell division occurs due to the multiplication of genetic information, DNA. The enzyme responsible for DNA synthesis duplicates a defective codon with a probability of 10 -6 , thereby producing a gene (mutant) different from the original gene. In most cases, this "error" does not cause any problems for the cells. However, when these mutations occur in certain genes that are important in regulating cell division, the defective cells immediately multiply due to the altered genetic information, and the process continues, resulting in a population of A cell that grows faster than neighboring cells. If the body does not recognize these rapidly proliferating cells in time, this process can lead to malignant tumors.

肿瘤的生成需要几年的时间。根据现行的试验方法,一个恶性细胞发展成一个直径为1cm的肿瘤,即一个细胞增殖1亿倍,需要4-5年的时间。在这段时间中,恶性细胞有足够的时间一直向机体扩散,并又开始形成其他的肿瘤。在与肿瘤作斗争中,只能获得有限结果的原因包括以下事实,在人体中的肿瘤被确诊之前,恶性细胞可能已遍及机体。It takes several years for tumors to develop. According to the current test method, it takes 4-5 years for a malignant cell to develop into a tumor with a diameter of 1cm, that is, a cell multiplies 100 million times. During this time, the malignant cells have had enough time to spread all the way through the body and start forming other tumors. Reasons for the limited results obtained in the fight against tumors include the fact that malignant cells may spread throughout the body before a tumor is diagnosed in the human body.

在长时间中,机体的防御机制能够与不断形成的肿瘤细胞保持平衡。翻转这种平衡的概率随人的年龄而增长。由于长期疾病持续占用了免疫系,使上述平衡颠倒,从而产生肿瘤,或由于长时间的紧张状态也会使所谓文明社会的危害影响(吸烟、含硝酸盐的饮用水、空气污染等)更容易对人造成伤害。身受上述各种影响的人们更可能成为恶性肿瘤的受害者。Over time, the body's defense mechanisms are able to maintain a balance with the ever-growing tumor cells. The probability of flipping this balance increases with a person's age. The above-mentioned balance is reversed, resulting in tumors, due to the continuous occupation of the immune system by long-term diseases, or the harmful effects of so-called civilized society (smoking, nitrate-containing drinking water, air pollution, etc.) are more likely due to prolonged stress cause harm to people. People affected by each of the above are more likely to be victims of malignancy.

另一方面,也有一些不利于肿瘤产生的因素。例如已观察到,三个孩子的母亲比两个、或一个或没有孩子的母亲患乳房肿瘤的可能性小。这可由以下事实加以解释,即伴随三次怀孕而产生的激素效应,可以减少产生恶性乳房肿瘤的机会。On the other hand, there are also some factors that are not conducive to tumor production. For example, it has been observed that mothers of three children are less likely to develop breast tumors than mothers of two, or one or no children. This can be explained by the fact that the hormonal effects that accompany three pregnancies reduce the chances of developing malignant breast tumors.

这些观察使人们注意到,有可能创造一些不利于肿瘤细胞产生突变的条件,这样,就能将它们消除。通过类似治疗的处理,可以在肿瘤发展到已能检出的尺寸之前,使人的机体自身能防御肿瘤的发生。These observations drew attention to the possibility of creating conditions unfavorable for tumor cells to mutate so that they could be eliminated. Treatment like therapy can enable the body to defend itself against tumors before they grow to a detectable size.

本发明的目的是要生产可以预防肿瘤疾病发生的食品,通过在机体中发生的一些变化,在肿瘤尚未发展到可检出其尺寸之前将其消除。The purpose of the present invention is to produce food that can prevent the occurrence of tumor diseases, and eliminate tumors before they have developed to a detectable size through some changes that occur in the body.

本发明是基于以下认识,根据气候情况,含有140-155ppm氘的水的氘浓度或用这种氘含量的水种植的植物的氘浓度,是保持正常的细胞增殖的先决条件。我们已认识到,与H浓度有关的氘浓度作为亚分子体系的要素,通过增加与H浓度有关的氘浓度可以激发细胞的分裂。进入机体的氘,对快速增殖的肿瘤细胞尤其是不可缺少的。The present invention is based on the realization that, depending on the climate, the deuterium concentration of water containing 140-155 ppm deuterium or of plants grown with water of this deuterium content is a prerequisite for maintaining normal cell proliferation. We have recognized that the deuterium concentration related to the H concentration acts as an element of the submolecular system, and cell division can be stimulated by increasing the deuterium concentration related to the H concentration. Deuterium entering the body is especially indispensable for rapidly proliferating tumor cells.

本发明的另一基础是认识到,贫化了氘的水、溶液和食物,由于降低了机体中的氘含量,可使肿瘤细胞停止分裂,因此,它们也能预防肿瘤的产生,并可治疗肿瘤疾病。Another basis of the present invention is the recognition that deuterium-depleted water, solutions and food can stop tumor cells from dividing due to the reduction of deuterium content in the body, so they can also prevent tumor development and treat tumor disease.

根据以上所述,本发明提供了一种生产氘含量为111-135ppm、适用于预防肿瘤疾病发生的食品的方法,该方法包括采用标准的电解法和/或蒸馏法生产氘含量为111-135ppm的水,并使用这样制得的水,采用标准的生产方法生产软饮料和啤酒,或用作藻类生产的营养液,或用于浇灌食品工业中所用的植物,从而获得氘含量较低的藻类和植物,然后,按常规的方法将其加工成食品。According to the above, the present invention provides a method for producing food with a deuterium content of 111-135ppm, which is suitable for preventing the occurrence of tumor diseases. and use the water so produced to produce soft drinks and beer using standard production methods, or as a nutrient solution for algae production, or for watering plants used in the food industry, thereby obtaining algae and The plants, then, are processed into food in conventional ways.

采用本发明生产的食品适用于预防肿瘤的发生。其原因在于,食用以贫化了氘的水生产的饮料和植物,会降低机体中的氘含量,减缓肿瘤细胞的增殖,最终使其逐渐消失。The food produced by the invention is suitable for preventing the occurrence of tumors. The reason for this is that eating beverages and plants produced from deuterium-depleted water will reduce the deuterium content in the body, slow down the proliferation of tumor cells, and eventually make them disappear.

用贫化了氘的水饲养的动物所进行的试验证实了这种方法的适用性。Experiments with animals fed deuterium-depleted water confirmed the applicability of this approach.

将PC-3标记的人体前列腺肿瘤移植到28只CBA/Ca标记的抑制了免疫性的老鼠体内。从移植后的第18天开始,通过让老鼠喝氘含量为115ppm的水,治疗14只老鼠。治疗持续16天,然后,将老鼠杀死从组织学上对肿瘤进行研究。PC-3-labeled human prostate tumors were transplanted into 28 CBA/Ca-labeled immunosuppressed mice. Starting on day 18 after transplantation, 14 mice were treated by allowing them to drink water with a deuterium content of 115 ppm. Treatment was continued for 16 days, after which mice were sacrificed to study tumors histologically.

肿瘤细胞的生长速度通过分裂的细胞与死亡的细胞之比测定。借助适当地制备的组织学切片,很容易测出上述比例。The growth rate of tumor cells is measured by the ratio of dividing cells to dying cells. These ratios are readily determined with the aid of properly prepared histological sections.

通过监测试验动物身上的肿瘤生长速率可以看出,用贫化了氘的水喂养的一组动物,其肿瘤的平均生长速率小于对照组的动物。考虑到以下明显的事实,在动物身上的肿瘤尺寸也取决于移植的肿瘤尺寸,因此,通过组织学试验可以比较客观地反映出贫化了氘的水的治疗效果,试验表明,在对照组中分裂细胞(有丝分裂)与死亡细胞(凋亡)之比为3.6∶1,而对用贫化了氘的水喂养的动物观察到的比例为1.5∶3。By monitoring the tumor growth rate in the test animals, it can be seen that the group of animals fed deuterium-depleted water had an average tumor growth rate less than that of the control animals. Considering the following obvious facts, the tumor size in animals also depends on the transplanted tumor size, therefore, the therapeutic effect of deuterium-depleted water can be more objectively reflected by the histological test, and the test shows that in the control group The ratio of dividing cells (mitosis) to dead cells (apoptosis) was 3.6:1 compared to the 1.5:3 observed for animals fed deuterium-depleted water.

食品工业中具有治疗效果的溶液,是由通常用于生产果汁、糖浆、软饮料和啤酒的原料并在这些原料中掺入活性剂而生产的。采用贫化了氘的水种植的藻类、蔬菜和水果的加工也可以采用标准的方法进行。Solutions with therapeutic effects in the food industry are produced from raw materials commonly used in the production of fruit juices, syrups, soft drinks and beer by incorporating active agents into these raw materials. Processing of algae, vegetables and fruits grown using deuterium-depleted water can also be performed using standard methods.

每1-2年,每次1-3星期食用本发明的食品是有益的。在治疗期间适于单独食用由贫化了氘的水生产的植物。Every 1-2 years, it is beneficial to eat the food of the present invention every 1-3 weeks. Plants produced from deuterium-depleted water are suitable for consumption alone during treatment.

本发明的方法的主要优点如下:The main advantages of the method of the present invention are as follows:

a)该方法使得有可能通过与调节细胞本身分裂的相同机制,干预细胞分裂的调节机制。a) The method makes it possible to intervene in the regulatory mechanisms of cell division by the same mechanisms that regulate cell division itself.

b)该方法使得有可能通过创造不适宜于肿瘤细胞增殖的条件,预防产生肿瘤,从而使机体变得能排除未来肿瘤的发生。b) The method makes it possible to prevent the development of tumors by creating conditions unfavorable for the proliferation of tumor cells, thereby enabling the body to become immune to future tumor occurrences.

c)本发明的方法所用的化合物无毒性副作用。c) The compounds used in the method of the present invention have no toxic side effects.

d)在生产过程中不产生有害废物。d) No hazardous waste is generated during the production process.

e)产品易于生产。e) The product is easy to produce.

f)与迄今所用的诱变性很强、且常导致产生甚至更多肿瘤的大多数细胞毒素相反,由于活性剂不是诱变性的,在治疗过程中不会产生突变体细胞。f) In contrast to most cytotoxins used to date which are very mutagenic and often lead to even more tumors, since the active agent is not mutagenic, no mutant cells are generated during the treatment.

通过以下非限制性的实施例,对本发明作详细说明。The invention is illustrated in detail by the following non-limiting examples.

实施例1Example 1

采用电解法生产贫化了氘的水Production of deuterium-depleted water by electrolysis

采用2-5伏直流电、将阴极与阳极隔开,电解15-20%的KOH水溶液。使阴极上产生的氘含量较低的氢气燃烧,然后,通过蒸馏系统将这样产生的水蒸气冷凝,并分别收集。这样制得的水中的氘含量为30-4ppm。将上述水与氘含量为150ppm的普通水按一定的比例混合,制成氘含量为111-135ppm的贫化了氘的水。Using 2-5 volts of direct current, separating the cathode from the anode, and electrolyzing 15-20% KOH aqueous solution. The deuterium-depleted hydrogen produced at the cathode is combusted, and the water vapor thus produced is condensed by a distillation system and collected separately. The deuterium content in the water thus obtained was 30-4 ppm. The above water is mixed with ordinary water with a deuterium content of 150 ppm in a certain proportion to prepare deuterium-depleted water with a deuterium content of 111-135 ppm.

这种产品可直接用于预防发生肿瘤疾病,或用作生产氘含量较低的化合物的原料。This product can be directly used to prevent the occurrence of tumor diseases, or be used as a raw material for the production of compounds with lower deuterium content.

实施例2Example 2

采用蒸馏法生产贫化了氘的水Production of deuterium-depleted water by distillation

在装有30-50块分馏塔板的蒸馏塔中,在45-50℃和50-60毫巴的压力下,使蒸馏的水沸腾。在蒸馏过程中,回流值为12-13,塔中的沉积物为10倍。采用这些参数,头馏分的氘浓度为20-30ppm。通过增加塔板数,可使水的氘含量进一步降低到1-10ppm。将这样生产的水与氘含量为150ppm的普通水混合,即可得到氘含量为111-135ppm的任一种氘浓度的水。The distilled water is boiled at 45-50° C. and a pressure of 50-60 mbar in a distillation column equipped with 30-50 fractionation trays. During the distillation, the reflux value was 12-13, and the sediment in the column was 10 times. Using these parameters, the deuterium concentration in the head fraction was 20-30 ppm. By increasing the number of plates, the deuterium content of water can be further reduced to 1-10ppm. The water produced in this way is mixed with ordinary water with a deuterium content of 150 ppm to obtain any deuterium concentration water with a deuterium content of 111-135 ppm.

实施例3Example 3

生产氘含量较低的果汁和充碳酸气的软饮料Production of juices and carbonated soft drinks with lower deuterium content

将氘含量为20-30ppm的蒸馏水按适当的比例与氘含量为150ppm的普通水混合,即可得到氘含量为111-135ppm的水。这种水可用于按常规的方法生产果汁和充碳酸气的软饮料。Distilled water with a deuterium content of 20-30 ppm is mixed with ordinary water with a deuterium content of 150 ppm in an appropriate proportion to obtain water with a deuterium content of 111-135 ppm. This water can be used for the conventional production of fruit juices and carbonated soft drinks.

实施例4Example 4

生产氘含量较低的啤酒Production of beer with lower deuterium content

将生产麦芽用的大麦浸泡在氘含量为111-135ppm的水中,然后将其散开铺成5-15cm厚的麦层,并在低温(5-15℃)和良好的通风条件下使其发芽。将发芽的大麦在50-75℃下干燥,并与胚芽根的残留物分离,然后研磨。将研磨后的麦芽与适量的氘含量为110-135ppm的水混合,并将该混合物的温度保持为50-75℃,然后过滤并与啤酒花一起煮沸。将啤酒麦芽汁过滤、冷却并用预先培养的酿酒酵母接种。在5-6℃下充分发酵10-14天,然后在密封桶中于0℃下后发酵几星期。最后,将这样生产的啤酒过滤、装瓶、并进行巴氏灭菌。啤酒中的氘含量主要取决于生产过程中所用的水的氘含量,而且水中的氘含量还影响乙醇和其他成分的氘含量。Soak the barley for malting in water with a deuterium content of 111-135ppm, spread it out into a 5-15cm thick barley layer, and germinate it under low temperature (5-15°C) and good ventilation . The germinated barley is dried at 50-75°C and separated from the residue of the germinated root, then ground. The milled malt is mixed with an appropriate amount of water with a deuterium content of 110-135ppm, and the mixture is kept at a temperature of 50-75°C, then filtered and boiled with hops. The beer wort was filtered, cooled and inoculated with pre-cultured Saccharomyces cerevisiae. Full fermentation at 5-6°C for 10-14 days, followed by post-fermentation in sealed vats at 0°C for several weeks. Finally, the beer thus produced is filtered, bottled, and pasteurized. The deuterium content of beer is mainly determined by the deuterium content of the water used in the production process, and the deuterium content of the water also affects the deuterium content of ethanol and other ingredients.

实施例5Example 5

在藻类养殖中生产高蛋白和低氘含量的食品Production of high protein and low deuterium food in algae farming

将95%(体积)空气和5%(体积)CO2的气体混合物连续地通过营养液鼓泡,培养普通的小球藻,该营养液的组成如下:5g/l KNO3;1.25g/l KH2PO4;2.5g/l MgSO4×7H2O;3mg/l FeSO4×7H2O;和1ml/l Arnon A-5溶液(0.4%的酒石酸0.6ml/l;H3BO3 2.86g/l;MnCl2×4H2O 1.81g/l;CuSO4×5H2O 0.08g/l;ZnSO4×7H2O 0.22g/l;Na2MoO4 0.21g/l和一滴H2SO4)。用氘含量为111-135ppm的水配制营养液。在一个200升的容器中,采用自然光,1个月内可生产1kg于物质。Chlorella vulgaris was cultivated by continuously bubbling a gas mixture of 95% by volume air and 5% by volume CO2 through a nutrient solution having the following composition: 5 g/l KNO3; 1.25 g/l KH 2 PO 4 ; 2.5g/l MgSO 4 ×7H 2 O; 3mg/l FeSO 4 ×7H 2 O; and 1ml/l Arnon A-5 solution (0.4% tartaric acid 0.6ml/l; H 3 BO 3 2.86 g/l; MnCl 2 ×4H 2 O 1.81g/l; CuSO 4 ×5H 2 O 0.08g/l; ZnSO 4 ×7H 2 O 0.22g/l; Na2MoO 4 0.21g/l and a drop of H 2 SO 4 ) . Prepare the nutrient solution with water with a deuterium content of 111-135 ppm. In a 200 liter container, 1 kg of substance can be produced in 1 month using natural light.

实施例6Example 6

生产低氘含量的蔬菜和水果Production of vegetables and fruits with low deuterium content

在各个方面均按标准的方法生产蔬菜和水果,唯一不同的是使用氘含量为111-135ppm的水灌溉。植物在光合作用过程中积聚较少的氘到有机化合物中。食用按这种方法生产的植物,机体中的氘浓度会显著地降低,这样,就可以抑制肿瘤细胞的分裂。Vegetables and fruit were produced in all respects according to the standard method, with the only difference being that water with a deuterium content of 111-135 ppm was used for irrigation. Plants accumulate less deuterium into organic compounds during photosynthesis. Eating plants produced in this way significantly reduces the concentration of deuterium in the body, thus inhibiting the division of tumor cells.

Claims (2)

1. deuterium concentration is the food of the prevention generation disease of 111-135ppm.
2. a deuterium content is 111-135ppm, is applicable to the production method of the food that the prevention tumor disease takes place, this method comprises that the electrolysis of employing standard and/or way of distillation production deuterium content are the water of 111-135ppm, and method production soft drink and the beer of using standard with the hydromining that makes like this, or the nutrient solution of producing as algae, or be used for watering the plant that is used for food industry, thereby obtain lower algae of deuterium content and plant, and method routinely is processed into food.
CN94195043A 1994-01-06 1994-01-06 Food for preventing occurrence of diseases and its preparation method Pending CN1143308A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101124313B (en) * 2005-02-08 2011-10-05 伍德福德联合有限公司 Alcoholic beverages rich in 1H216O
CN103300449A (en) * 2009-08-21 2013-09-18 普罗蒂亚有限责任公司 Alcoholic compositions having a lowered risk of acetaldehydemia

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101124313B (en) * 2005-02-08 2011-10-05 伍德福德联合有限公司 Alcoholic beverages rich in 1H216O
CN103300449A (en) * 2009-08-21 2013-09-18 普罗蒂亚有限责任公司 Alcoholic compositions having a lowered risk of acetaldehydemia
CN103300449B (en) * 2009-08-21 2015-05-06 杜特里亚饮料有限责任公司 Alcoholic compositions having a lowered risk of acetaldehydemia

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