Disclosure of Invention
The invention mainly provides an intelligent sample refrigerating box for a mycobacterium tuberculosis drug resistance experiment, which is used for solving the technical problems in the background technology.
The technical scheme adopted by the invention for solving the technical problems is as follows:
an intelligent sample refrigerating box for a mycobacterium tuberculosis drug resistance experiment comprises a box body, a refrigerating unit, a split type box door, a lifting and transporting mechanism, an isolating and door moving mechanism and a layered storage mechanism, wherein the refrigerating unit is arranged on the back of the box body, the split type box door is arranged in front of the box body, the lifting and transporting mechanism, the isolating and door moving mechanism and the layered storage mechanism are sequentially arranged in the box body from front to back, the split type box door is divided into two door plates, a controller is arranged on the outer surface of one door plate, sample transfer ports are formed in the two door plates, an opening and closing door capable of moving up and down is arranged in each sample transfer port, a machine vision camera is arranged at the top of each sample transfer port close to the inner side of the opening and closing door, and the machine vision camera is used for shooting images and then transmitting the images to the controller for analysis and recording;
the lifting and transporting mechanism comprises lifting screw rods symmetrically arranged at two sides in the box body, and a front sliding rod and a rear sliding rod which are arranged in the front-back direction and are arranged at the middle positions of the two lifting screw rods, a lifting tray capable of moving up and down is arranged between the two lifting screw rods and the front sliding rod and the rear sliding rod respectively, an infrared distance meter is arranged right below the lifting tray and on the bottom wall in the box body, and the infrared distance meter is electrically connected with the controller;
the isolation sliding door mechanism comprises an isolation heat-preservation sliding door, and a driving device for implementing translational motion of the isolation heat-preservation sliding door is arranged on the front end surface of the top of a door frame of the isolation heat-preservation sliding door;
mechanism is stored including the isolation backplate that is vertical mode setting with set up in keep apart the branch storehouse baffle of backplate front end center department, the both sides from the top down of dividing the storehouse baffle equidistance in proper order is provided with a plurality of thing trays of putting, put and be provided with horizontal migration's fork around can on the thing tray.
Preferably, the door plant is located the upper end of sample transmission mouth and is offered holding tank and resettlement groove in the front and back side by side mode, open and close the door activity and set up in the holding tank, the resettlement inslot is provided with electronic sharp module, and the removal slider of this electronic sharp module is connected with open and close door top one side.
Preferably, the inner side of the bottom of the sample transfer port is rotatably connected with a damping spring rotating plate, and when the damping spring rotating plate rotates from a vertical state to a horizontal state, the lifting tray is contacted with the damping spring rotating plate when moving up and down.
Preferably, the one end of lift tray is equipped with internal thread screw lug, internal thread screw lug cup joints in the lift lead screw outside that corresponds and is threaded connection, the lift tray other end is equipped with the haplopore lug, two the haplopore lug cup joints respectively on preceding slide bar and back slide bar and is sliding connection, just lift tray upper surface bilateral symmetry is provided with the blend stop, is equipped with two slots between two blend stops on the same lift tray, and this slot width and height all are greater than the width and the height of fork.
Preferably, keep apart to keep warm and move the door and be equipped with two altogether keep apart to keep warm and move the door and misplace and the activity sets up in the door frame around being, and the terminal surface both sides are the dislocation about being respectively before the top of this door frame and are provided with left stroke strip mouth and right stroke strip mouth, and the inside from the top down of top of this door frame corresponds in proper order left stroke strip mouth and right stroke strip mouth have seted up left activity spacing storehouse and right activity spacing storehouse, the interval from the front to the back in left side activity spacing storehouse is greater than the interval in right side activity spacing storehouse, and when two keep apart to keep warm and move the door and be in the closed condition, the both sides edge of keeping away from mutually is provided with left enhancement strip and right enhancement strip respectively.
Preferably, the number of the driving devices is two, each driving device comprises a T-shaped sliding block, a motor, an L-shaped connecting rod and a friction moving wheel, the motor is fixed at one end of the T-shaped sliding block and penetrates through the T-shaped sliding block through an output shaft, the two T-shaped sliding blocks are movably inserted into the left stroke strip opening and the right stroke strip opening respectively and are inserted into the left movable limiting bin and the right movable limiting bin respectively through the output shafts of the two motors to be connected with the corresponding friction moving wheels, and the two friction moving wheels are in friction contact with wheel grooves formed in the inner bottom walls of the left movable limiting bin and the right movable limiting bin respectively.
Preferably, two the overall structure of L type connecting rod is unanimous, but length is inconsistent, and length is longer L type connecting rod one end with insert the T word slider of establishing in the stroke strip of a left side and be connected, the other end is strengthened the strip with a left side and is connected, and length is shorter L type connecting rod one end with insert the T word slider of establishing in the stroke strip of a right side and be connected, the other end is strengthened the strip with the right side and is connected.
Preferably, sliding grooves are symmetrically arranged on two sides of the upper surface of the storage tray, strip-shaped openings are arranged at the bottom in the sliding grooves, a semicircular arc long groove is formed in the center of the lower surface of the object placing tray, an adjusting screw rod is arranged in the semicircular arc long groove, one end of the adjusting screw rod penetrates through the isolation back plate and extends to the rear end to be connected with an adjusting motor, and the lower end of the object placing tray is movably provided with a transverse moving rod, the center of one side of the transverse moving rod is provided with a semi-circular arc-shaped convex block, the semi-arc-shaped convex block is embedded into the semi-arc-shaped long groove and is connected in a sliding way, the adjusting screw rod penetrates through the semi-arc-shaped convex block and is connected in a threaded way, the both ends symmetry that transverse movement pole is close to half-circular arc lug one side is equipped with the connecting rod, two the connecting rod alternates respectively put two bar mouth walls on the thing tray and extend to the spout inside with correspond the fork is connected.
Preferably, the length of fork is less than spout length, and the fork height is unanimous with the perpendicular degree of depth of spout, and the fork front end is established to the inclined plane structure, and fork rear end top is equipped with blocks the piece, and fork top surface is equipped with anti-skidding rubber pad, just the interval of putting two spouts on the tray with two slot intervals on the lift tray equal.
Preferably, the infrared distance measuring device comprises a stainless steel trapezoidal table shell, and rubber buffer blocks are arranged at four top corners of the top of the stainless steel trapezoidal table shell one by one.
Compared with the prior art, the invention has the beneficial effects that:
in the drug resistance research experiment of mycobacterium tuberculosis, the safety of storage and taking is obviously improved in the aspect of cold storage and preservation of samples, the cold storage box door does not need to be opened for storage and taking, after the sample transfer port is opened in the lifting mode of the opening and closing door, information data is recorded by shooting through a machine vision camera, the cold storage box is mainly used for counting samples, the samples are pushed into a lifting tray to be automatically lifted after the data is recorded by a controller, the isolation heat preservation sliding door is opened, the fork on the storage tray is moved out to move the samples to the position above the storage tray for cold storage, the whole storage and taking working process is efficient, accurate and convenient, the intelligent degree is effectively improved, and the experiment risk of researchers is greatly reduced.
The present invention will be explained in detail below with reference to the drawings and specific embodiments.
Detailed Description
In order to facilitate an understanding of the invention, the invention will now be described more fully hereinafter with reference to the accompanying drawings, in which several embodiments of the invention are shown, but which may be embodied in different forms and not limited to the embodiments described herein, but which are provided so as to provide a more thorough and complete disclosure of the invention.
In the embodiment, referring to fig. 1-11, an intelligent sample refrigerator for mycobacterium tuberculosis drug resistance experiments comprises a box body 1, a refrigerating unit 2 disposed on the back of the box body 1, a split door 3 disposed right in front of the box body 1, and a lifting and transporting mechanism, an isolating and moving door mechanism, a layered storage mechanism disposed in the box body 1 in sequence from front to back, wherein the split door 3 is divided into two door panels, a controller 10 is disposed on the outer surface of one door panel, a sample transfer opening 31 is disposed on each of the two door panels, an opening and closing door 321 capable of moving up and down is disposed in the sample transfer opening 31, an accommodating groove 32 and a placing groove 33 are disposed on the upper end of the sample transfer opening 31 in a front-back side-by-side manner, the opening and closing door 321 is movably disposed in the accommodating groove 32, an electric linear module 331 is disposed in the placing groove 33, and a moving slider of the electric linear module 331 is connected to one side of the top of the opening and closing door 321, the opening and closing door 321 is driven to move up and down in the accommodating groove 32 by the operation of the electric linear module 331, a machine vision camera 34 (model medium-moment constant distance A.7201.CN) is arranged at the top of the sample transfer port 31 close to the inner side of the opening and closing door 321, the machine vision camera 34 is used for shooting images and transmitting the images to the controller 10 for analysis and recording, is mainly used for shooting, analyzing and counting the entering and exiting of samples, so that the access information is accurate and real-time, the research and recording work of researchers are convenient, the refrigerating unit 2 is a common refrigerator refrigerating device, the cold air branch pipeline 21 is arranged near the back side in the box body 1 and is used for uniformly conveying the cold air to the air outlets 71 on the isolation back plate 7, and the air outlets 71 are correspondingly arranged above the storage tray 9 one by one, so that the sample can be better refrigerated when stored;
specifically, referring to fig. 1, 2 and 4, the lifting and transporting mechanism includes lifting screws 62 symmetrically disposed at two sides of the interior of the box 1, and a front slide bar 63 and a rear slide bar 64 arranged in a front-back manner and disposed at the middle position of the two lifting screws 62, a lifting tray 65 capable of moving up and down is disposed between the two lifting screws 62 and the front slide bar 63 and the rear slide bar 64, respectively, a lifting motor 6 is symmetrically disposed at two sides of the top of the box 1, two bevel gear members 61 in a vertical engaging structure are disposed at the front end of the lifting motor 6, an output shaft of the lifting motor 6 is connected with a bevel gear in a vertical state for driving another bevel gear in a horizontal state to rotate, wherein the tops of the two lifting screws 62 penetrate through the box 1 and are connected with the two bevel gears in a horizontal state, respectively, providing power transmission for lifting the lifting tray 65, a pedestal bearing is disposed between the bottom of the lifting screws 62 and the inner bottom wall of the box 1, the lifting screw 62 is inserted into the bearing 621 with a base to realize a rotatable function, the infrared distance measuring device 4 is arranged under the lifting tray 65 and on the bottom wall of the box body 1, the infrared distance measuring device 4 is electrically connected with the controller 10, the infrared distance measuring device 4 comprises a stainless steel trapezoid table shell 41, rubber buffer blocks 42 are arranged at four top corners of the stainless steel trapezoid table shell 41 one by one to prevent the lifting tray 65 from directly knocking the infrared distance measuring device 4 after being lowered, the height distance of the lifting tray 65 is measured by the infrared distance measuring device 4, therefore, in the setting data of the controller 10, the data of each height point after setting can be automatically controlled and analyzed to determine whether the height of the lifting tray 65 reaching each position is proper or not, for example, when a sample is stored, the height of the lifting tray 65 is corresponding to the height inside of the sample transfer port 31, after the sample is pushed in, then, the storage tray 9 is moved according to the height position of the storage tray 9 to be stored, after the storage tray reaches a corresponding position, the isolation heat preservation moving door 8 is opened, at the moment, the fork 92 moves out to receive and return the sample to the storage tray 9, especially, when the fork 92 moves into the slot 654 on the lifting tray 65, the lifting tray 65 firstly descends about 1-5mm to completely separate the sample from the fork 92, at the moment, the fork 92 returns to the storage tray 9 very smoothly, when the sample needs to be taken out, the fork 92 moves the sample to the upper part of the lifting tray 65, the lifting tray 65 can only ascend to receive the bottom of the bracket of the sample, so that the fork 92 can retreat smoothly, and the working process can be realized by setting a corresponding program in the controller 10;
specifically, referring to fig. 1, 4 and 11, one end of the lifting tray 65 is provided with an inner screw hole bump 651, the inner screw hole bump 651 is sleeved on the outer portion of the corresponding lifting screw 62 and is in threaded connection, the other end of the lifting tray 65 is provided with a single-hole bump 652, the two single-hole bumps 652 are respectively sleeved on the front sliding rod 63 and the rear sliding rod 64 and are in sliding connection, two sides of the upper surface of the lifting tray 65 are symmetrically provided with a barrier 653, two ends of the barrier 653 are both designed as inclined planes, and are inclined from the outside to the inside, so that the sample bracket can be guided when entering the lifting tray 65, two slots 654 are arranged between the two barrier 653 on the same lifting tray 65, the width and height of each slot 654 are greater than the width and height of a fork 92, the inner side of the bottom of the sample transfer port 31 is rotatably connected with the damping spring rotating plate 35, and when the damping spring rotating plate 35 rotates from a vertical state to a horizontal state, the lifting tray 65 contacts with the damping spring rotating plate 35 when moving up and down, and this part needs to be described that a rotatable folding supporting plate frame 5 is arranged at the lower position outside the sample transfer port 31, the folding supporting plate frame 5 is rotatably connected in one accommodating groove 36 at the lower end of the sample transfer port 31, and support rods 52 are rotatably connected in the horizontal direction at two sides in the accommodating groove 36, a pull rope 51 is connected at the front end of the plate body of the folding supporting plate frame 5, when the lifting tray is used, the pull rope 51 is pulled to rotatably support the folding supporting plate frame 5, then the two support rods 52 are rotated to support the plate body of the folding supporting plate frame 5, so that the plate body is flush with the bottom of the sample transfer port 31, a sample is conveniently placed on the folding supporting plate frame 5 and then pushed into the sample transfer port 31, when the plate is pushed again after data is shot and extracted, the damping spring rotating plate 35 is rotated to the horizontal state from the vertical state, as a connecting bridge, when the lifting tray 65 is at a proper height, a sample can be directly pushed in and moved onto the lifting tray 65 through the damping spring rotating plate 35, the damping spring rotating plate 35 rebounds slowly, so that a researcher can conveniently push in the sample and quickly pull out the sample, when the sample is taken out, the damping spring rotating plate 35 is pressed inwards and downwards by one hand, then the bracket of the sample is moved onto the outside folding supporting plate frame 5,
specifically, referring to fig. 2, 8, 9 and 10, the isolation sliding door mechanism includes two isolation thermal sliding doors 8, a driving device 85 for the isolation thermal sliding doors 8 to perform a translational motion is disposed on a front end surface of a top portion of the isolation thermal sliding doors 8, the two isolation thermal sliding doors 8 are disposed in a front-back staggered manner and movably disposed in a door frame, two sides of the front end surface of the top portion of the door frame are respectively disposed with a left travel bar opening 83 and a right travel bar opening 84 in a vertically staggered manner, a left movable limiting bin 87 and a right movable limiting bin 88 are disposed on an inner portion of a top end of the door frame corresponding to the left travel bar opening 83 and the right travel bar opening 84 in sequence from top to bottom, a distance from the front to the back of the left movable limiting bin 87 is greater than a distance from the right movable limiting bin 88, and when the two isolation thermal sliding doors 8 are in a closed state, two distant side edges are respectively disposed with a left reinforcing bar 81 and a right reinforcing bar 82, the two driving devices 85 are provided, each driving device 85 comprises a T-shaped sliding block 851, a motor 852, an L-shaped connecting rod 853 and a friction moving wheel 854, the motor 852 is fixed at one end of the T-shaped sliding block 851 and penetrates through the T-shaped sliding block 851 through an output shaft, the two T-shaped sliding blocks 851 are movably inserted into the left stroke slot 83 and the right stroke slot 84 respectively and are connected with the corresponding friction moving wheel 854 through the output shafts of the two motors 852 to be inserted into the left movable limiting bin 87 and the right movable limiting bin 88 respectively, the two friction moving wheels 854 are in friction contact with wheel grooves arranged on the inner bottom walls of the left movable limiting bin 87 and the right movable limiting bin 88 respectively, the two L-shaped connecting rods 853 have the same integral structure but different lengths, one end of the L-shaped connecting rod 853 with the longer length is connected with the T-shaped sliding block 851 inserted into the left stroke slot 83, and the other end is connected with the left reinforcing bar 81, and one end of the L-shaped connecting rod 853 having a shorter length is connected to a T-shaped slider 851 inserted into the right stroke slot 84, and the other end is connected to the right reinforcing bar 82. Keep apart and keep warm and still will be provided with pulley 86 between the bottom of moving door 8 and the interior diapire of door frame, it also is convenient for carry out translation motion when moving door 8 to support to keep apart to keep warm, it is rotatory to utilize motor 852 work to drive friction removal wheel 854, factor through frictional force, cooperation T word slider 851 and L type connecting rod 853 drive the isolation that corresponds and keep warm and move door 8 and carry out the translation, conveniently access the sample, under the circumstances of closing, keep apart in the clearance that keeps warm and move between the door 8 and be close to for two, and keep apart and keep warm and move door 8 and all set up the low temperature resistant adhesive tape of heat preservation and sealing usefulness in the clearance that the door frame is close to, it is too fast to be used for protecting air conditioning and prevent to run off, and also be provided with corresponding low temperature resistant adhesive tape on the outer wall that divides storehouse baffle 72 to be close to keep apart and keep warm and move door 8 one side, be used for keeping apart the bin of both sides.
Specifically, referring to fig. 3, 5, 6, and 7, the layered storage mechanism includes a vertical isolation backboard 7 and a bin separation partition plate 72 disposed at the center of the front end of the isolation backboard 7, wherein a plurality of storage trays 9 are sequentially disposed at equal intervals from top to bottom on both sides of the bin separation plate 72, a fork 92 capable of moving horizontally back and forth is disposed on the storage tray 9, sliding slots 91 are symmetrically disposed on both sides of the upper surface of the storage tray 9, a strip-shaped opening 98 is disposed at the bottom of the sliding slot 91, a semi-circular arc-shaped long groove 97 is disposed at the center of the lower surface of the storage tray 9, an adjusting screw 96 is disposed in the semi-circular arc-shaped long groove 97, one end of the adjusting screw 96 penetrates through the isolation backboard 7 and extends to the rear end to be connected with an adjusting motor 93, a transverse moving rod 95 is movably disposed at the lower end of the storage tray 9, a semi-circular arc-shaped projection 951 is disposed at the center of one side of the transverse moving rod 95, the semi-circular-arc-shaped projection 951 is embedded in the semi-circular arc-shaped long groove 97 to be connected in a sliding manner, the adjusting screw 96 penetrates through the semi-circular arc-shaped convex block 951 and is in threaded connection, two ends of one side of the transverse moving rod 95, which is close to the semi-circular arc-shaped convex block 951, are symmetrically provided with connecting rods 952, the two connecting rods 952 are respectively inserted into two strip-shaped openings 98 on the object placing tray 9 and extend into the sliding groove 91 to be connected with corresponding fork 92, wherein the adjusting motor 93 is arranged on the back surface of the isolation back plate 7, a shaft sleeve 94 is arranged at the joint of the adjusting motor 93 and the adjusting screw 96 to improve the sealing property, the adjusting motor 93 drives the adjusting screw 96 to rotate, so that the transverse moving rod 95 slides forwards and backwards in the semi-circular arc-shaped long groove 97, the connecting rods 952 at two ends of the transverse moving rod 95 drive the two fork 92 to move in the two sliding grooves 91, the storage and the removal of a sample are realized, the length of the fork 92 is smaller than that of the sliding groove 91, the fork 92 can be completely stored in the sliding groove 91, and the height of the fork 92 is consistent with the vertical depth of the sliding groove 91, fork 92 front end is established to the inclined plane structure, be convenient for with the object contact back shovel object, fork 92 rear end top is equipped with blocks 921, fork 92 top surface is equipped with anti-skidding rubber pad 922, when anti-skidding rubber pad 922, the bracket of sample is when depositing, main contact surface is on anti-skidding rubber pad 922, even weight pushes down, lead to the bracket bottom of sample and put thing tray 9 surface contact when too big, also can assist the promotion through blockking 921, the interval of putting two spout 91 on the thing tray 9 equals with two slots 654 intervals on the lifting tray 65, can make things convenient for inside the accurate slot 654 that inserts of fork 92.
According to the content of the above embodiments, in combination with the work flow of the present invention, please refer to fig. 12, a control system program running in the controller 10 is correspondingly provided with an opening and closing door unit 101, a door electromagnetic attraction unit 102, a vision camera counting unit 103, a sample lifting and transporting unit 104, an isolation moving door unit 105, a fork movement control unit 106, a refrigerating unit 107, and an infrared distance measurement fixed point unit 108, wherein the opening and closing door unit 101 correspondingly controls the electric linear module 331 to operate the opening and closing door 321;
the vision camera counting unit 103 performs image shooting corresponding to the machine vision camera 34, analyzes the image shooting through the controller 10, counts the image shooting, and records data;
the sample lifting and transporting unit 104 correspondingly controls the lifting motor 6 to work to drive the lifting tray 65 to carry out height adjustment;
the isolation sliding door unit 105 drives the isolation heat-preservation sliding door 8 to perform left-right translation motion corresponding to the work of the control motor 852;
the fork movement control unit 106 correspondingly controls the adjusting motor 93 to work to drive the fork 92 to move in a translation manner so as to store and take samples;
the refrigeration unit 107 has data interaction with the refrigeration unit 2, and can control the functions of temperature adjustment, air flow adjustment, temperature monitoring and the like;
the infrared distance measurement fixed point unit 108 can monitor distance data corresponding to the infrared distance measuring device 4, so that the fixed lifting tray 65 can be lifted and lowered under the set data limit;
the box door electromagnetic attraction unit 102 is set according to user requirements, when the split box door 3 needs to be locked in use, the existing electromagnetic attraction lockset is additionally arranged, then the split box door 3 can be firmly attracted and locked after being tightly closed, and unlocking can be operated on the controller 10 through the box door electromagnetic attraction unit 102;
in addition to the above functional units, referring to fig. 12, the controller 10 is further configured with a screen display unit 109, a networking module 110, a radio frequency receiving unit 111, a password unlocking unit 112, and an entry keyboard unit 113 by combining its own structural features, wherein the screen display unit 109 displays data corresponding to a display screen on the controller 10;
the networking module 110 is a common function used by the controller 10 for remote data transmission;
the setting of the rf receiving unit 111 is that, firstly, according to whether a researcher needs to stick an rf tag on a reagent tube or a bottle of a sample, in the case of the rf tag, the radio frequency tag can be recorded at a corresponding rf signal receiving position on the controller 10 for accessing;
the password unlocking unit 112 and the entry keyboard unit 113 are conventional technologies of general intelligent control devices, and can be set according to the requirements of users.
The specific operation flow of the invention is as follows:
firstly, the controller 10 starts the refrigeration operation of the refrigeration box, the refrigeration unit 2 is used for providing cold air for the interior of the box body 1, the cold air is uniformly conveyed to the air outlets 71 on the isolation back plate 7 through the cold air branch pipelines 21 arranged close to the back surface in the box body 1, and the air outlets 71 are correspondingly arranged above the storage tray 9 one by one;
when a sample is stored, the controller 10 drives the opening and closing door 321 to move upwards in the accommodating groove 32 by controlling the operation of the electric linear module 331, then pulls the pull rope 51 to rotatably support the folding supporting plate frame 5, then rotates the two support rods 52 to support the plate body of the folding supporting plate frame 5 to be flush with the bottom of the sample transfer port 31, so that the sample can be conveniently placed on the folding supporting plate frame 5 and then pushed into the sample transfer port 31, images are shot by the machine vision camera 34 and then are transmitted to the controller 10 for analysis and recording, at the moment, the height of the lifting tray 65 is corresponding to the inner side of the sample transfer port 31, after the sample is pushed in, the lifting tray moves according to the height position of the storage tray 9 to be stored, after the corresponding position is reached, the isolation heat-preservation moving door 8 is opened, at the moment, the fork 92 moves out to receive the sample and returns the sample to the storage tray 9, particularly, when the fork 92 moves into the slot 654 on the lifting tray 65, the lifting tray 65 should first descend by about 1-5mm to completely separate the sample from the fork 92, at this time, the fork 92 returns to the placing tray 9, and when the sample needs to be taken out, the fork 92 moves the sample above the lifting tray 65, the lifting tray 65 can only ascend to catch the bottom of the bracket of the sample, so that the fork 92 can smoothly retreat, the height of the lifting tray 65 continues to ascend to the corresponding height inside the sample transfer port 31, then the damping spring rotating plate 35 is pressed inwards by the outstretched hand, the sample passes through the machine vision camera 34, is shot again and is conducted to the controller 10 for analysis, and is recorded as the taken-out data, and finally, the bracket of the sample is moved to the outside folding bracket 5.
The invention is described above with reference to the accompanying drawings, it is obvious that the invention is not limited to the above-described embodiments, and it is within the scope of the invention to adopt such insubstantial modifications of the inventive method concept and solution, or to apply the inventive concept and solution directly to other applications without modification.