CN103300011B - A kind of Pesticidal combination containing fluorine mite piperazine - Google Patents

Abstract

The invention discloses an insecticidal composition containing flufenazine. The main feature of the composition is that it contains active ingredient A and active ingredient B. Wherein the active ingredient A is flufenazine, the active ingredient B is any one of pyridaben, propargid, and tebufenpyrad, and the weight ratio of the active ingredient A to the active ingredient B is 1:80 to 80:1, and the combination It can be made into wettable powder, water dispersible granule, suspension concentrate, suspoemulsion, water emulsion, microemulsion, microcapsule suspension, microcapsule suspension-suspension concentrate. The composition of the invention can prevent and control various pests on wheat, cotton, fruit trees, vegetables and tea trees, has obvious synergistic effect, reduces the dosage of pesticides, is safe for humans and animals, has no chemical harm, and has good environmental compatibility; The adhesion of the preparation is enhanced, and it is resistant to rain erosion.

Description

A kind of insecticidal composition containing flufenazine

technical field

The invention belongs to the technical field of pesticides and relates to an insecticidal composition containing flufenazine.

Background technique

Diflovidazin (diflovidazin), molecular formula: C ₁₄ H ₇ CLF ₂ N ₄ , diflovidazin is active in contact with eggs and transdermally, attracting adult mites to feed on, and also prevents mites in pupal stage. The compound has a unique mechanism of action. It not only has excellent activity against eggs and adult mites, but also causes female mites to produce unsound eggs, leading to the eradication of mites. At the same time, it also has a good effect on pear psyllids, elm oyster scales, leafhoppers, etc. , and safe to natural enemies and the environment.

Pyridaben, chemical name: bis[tri-2-methyl-phenylpropyl) tin] oxide, chemical formula: C ₁₉ H ₂₅ ClN ₂ OS. Pyridaben is a broad-spectrum, contact-killing acaricide, which can be used to control a variety of plant-eating pest mites. It has good effects on eggs, larvae, nymphs and adults, and it is also effective on adult mites in the migratory stage. Obvious quick kill effect. The medicine is not affected by temperature changes, and satisfactory results can be achieved no matter whether it is used in early spring or autumn.

Propargite, chemical name: 2-(4-tert-butylphenoxy)cyclohexylprop-2-ynyl sulfite, chemical formula: C ₁₉ H ₂₆ O ₄ S. Acetyl is a low-toxic broad-spectrum organic sulfur acaricide, which has contact and stomach poisoning effects, no systemic and osmotic conduction effects, effective for adults and nymphs, and poor egg killing effect. The drug effect can be improved under the above conditions, but it will decrease with low temperature below 20°C. It can be used to control harmful mites in cotton, vegetables, apples, citrus, tea, flowers and other crops, and it is relatively safe to most natural enemies.

Tebufenpyrad (Tebufenpyrad), chemical formula: C ₁₈ H ₂₄ CLN ₃ O, Tebufenpyrad is an amide acaricide. It has excellent effects on various mites, Hemiptera and Homoptera pests, and has quick-acting and high-efficiency on all growth stages of mites, long-lasting effect, no systemic, but has osmotic activity, and is effective on target crops Has excellent selectivity.

In the actual process of agricultural production, the most likely problem in the control of pests and pest mites is the emergence of drug resistance. Combination of ingredients from different varieties is a common method for controlling resistant pests and harmful mites. Different ingredients are compounded, and according to the actual application effect, it is judged whether a certain compound is synergistic, additive or antagonistic. In most cases, the compounding effect of pesticides is an additive effect, and there are very few compoundings that really have a synergistic effect, especially those with a very obvious synergistic effect and a high co-toxicity coefficient. A large number of tests by the inventors have found that the compounding of flufenazine, pyridaben, pyridaben, and tebufenpyrad has a significant synergistic effect, excellent environmental compatibility, and greatly reduces the amount of pesticides used.

Contents of the invention

In addition to the two active components of flufenazine and pyridaben, pyridaben, and tebufenpyrad, the insecticidal composition proposed by the present invention also contains an appropriate amount of surfactant and carrier.

An insecticidal composition containing flufenazine, comprising active ingredient A and active ingredient B, characterized in that: active ingredient A is flufenazine, and active ingredient B is any A kind of, and the weight ratio of active ingredient A and active ingredient B is 1:80～80:1.

The insecticidal composition is characterized in that the weight ratio of the active ingredient A to the active ingredient B is 1:60-40:1.

The insecticidal composition is characterized in that the weight ratio of flufenazine to pyridaben is 1:40-20:1, preferably 1:20-10:1.

The insecticidal composition is characterized in that the weight ratio of flufenazine to propargite is 1:30-10:1, preferably 1:15-5:1.

The insecticidal composition is characterized in that the weight ratio of flufenazin to tebufenpyrad is 1:30-10:1, preferably 1:15-5:1.

The insecticidal composition is characterized in that: the composition is made into wettable powder, water dispersible granule, suspension, suspoemulsion, water emulsion, microemulsion, microcapsule suspension, microcapsule suspension-suspension.

The insecticidal composition is used for controlling pests on wheat, cotton, fruit trees, vegetables and tea trees.

The control pests include: spider mites, yellow spiders, rust ticks, rust spiders, tea yellow mite, cinnabarinus, Tetranychus urticae, spider mite, pear psyllid, elm oyster scale and leafhopper.

The pesticidal composition of the present invention contains at least one surfactant to facilitate the dispersion of the active ingredient in water during application. The surfactant content is 5%-30% of the total weight of the preparation, and the balance is solid or liquid diluent. The surfactant selected for the insecticidal composition of the present invention is well known to those skilled in the art: it can be selected from one or more of dispersants, wetting agents, emulsifiers or defoamers.

The wettable powder contains the following components: 1%-80% of active ingredient A, 1%-80% of active ingredient B, 5%-10% of dispersant, 2%-10% of wetting agent, and the balance of filler.

Active ingredient A, active ingredient B, dispersant, wetting agent, and filler are mixed, mixed uniformly in a mixing tank, pulverized by a jet mill, and then mixed uniformly to produce the wettable powder product of the present invention.

When the composition is made into water-dispersible granules, the following components are included: 1%-80% of active ingredient A, 1%-80% of active ingredient B, 3%-12% of dispersant, 1%-8% of wetting agent, disintegrant 1%~10%, binder 0~8%, filler balance.

The active ingredient A, active ingredient B, dispersant, wetting agent, disintegrating agent, filler, etc. are jet milled together to obtain the required particle size, and the granulation material is obtained. The water-dispersible granule product of the present invention is obtained by quantitatively sending the material into a fluidized bed granulation dryer for granulation and drying.

When the composition is made into a suspension, it includes the following components: active ingredient A 1%-60%, active ingredient B 1%-60%, dispersant 2-10%, wetting agent 2-10%, defoamer 0.1-2% , Thickener 0.05 ~ 2%, antifreeze agent 0 ~ 8%, deionized water added to 100%.

The dispersant, wetting agent, defoamer, thickener, antifreeze agent, and emulsifier in the above formula are mixed evenly through high-speed shearing, and the active ingredient A and active ingredient B are added and ball milled in a ball mill for 2 to 3 hours. The particle diameters of all the particles are below 5 μm to obtain the suspension product of the present invention.

When the composition is made into a suspoemulsion, it includes the following components: 1%-60% of active ingredient A, 1%-60% of active ingredient B, 2%-12% of emulsifier, 2%-10% of dispersant, and 0.1% of defoamer ~2%, thickener 0.05%~1%, antifreeze agent 0%~8%, stabilizer 0%~5%, deionized water to 100%.

Mix the dispersant, defoamer, thickener, antifreeze, and stabilizer in the above formula evenly through high-speed shearing, add active ingredient A original drug, and ball mill in a ball mill for 2 to 3 hours to make the particle size completely Below 5 μm, the active ingredient A suspension is prepared, and then the active ingredient B original drug, emulsifier and various auxiliary agents are directly emulsified into the suspension with a high-speed stirrer to obtain the suspoemulsion product of the present invention.

When the composition is made into water emulsion, it contains the following components: 1%-60% of active ingredient A, 1%-60% of active ingredient B, 0%-30% of solvent, 1%-15% of emulsifier, and 0% of antifreeze ～10%, thickener 0%～2%, defoamer 0.01%～2%, deionized water to make up the balance.

Mix the above formulas, add active ingredients, solvents, emulsifiers, and co-emulsifiers together to dissolve into a uniform oil phase; mix water, antifreeze, thickener, and defoamer together to form a uniform water phase . Under high-speed stirring, the water phase is added to the oil phase to prepare the water emulsion product of the present invention.

When the composition is made into a microemulsion, it contains the following components: 1% to 60% of active ingredient A, 1% to 60% of active ingredient B, 0% to 30% of solvent, 3% to 20% of emulsifier, and 0% to 12% of co-emulsifier %, antifreeze 0% to 10%, defoamer 0.01% to 2%, stabilizer 0% to 4%, and deionized water to make up the balance.

Dissolve active ingredient A and active ingredient B in a homogenizer with solvent and co-solvent; add emulsifier, stabilizer, antifreeze, and water into the homogenizer with the above solution, and then vigorously Mix and homogenize to finally obtain the microemulsion product of the present invention with a clear and transparent appearance.

The microcapsule suspension prepared from the composition comprises the following components: 1%-60% of active ingredient A, 1%-60% of active ingredient B, 1%-12% of polymer capsule wall material, 2%-10% of surfactant, 1% to 15% of organic solvent, 1% to 8% of emulsifier, 0.1% to 5% of pH regulator, and deionized water to 100%.

Add the polymer capsule wall material to a PH regulator and heat it to a certain temperature to obtain a viscous liquid, then add water to dilute to form a stable prepolymer solution, dissolve the active ingredient B and active ingredient A in the organic solvent, and then add the prepolymer In the polymer solution, add emulsifier and surfactant, and fully shear and stir to disperse into extremely fine particles, then add pH regulator, and heat up, catalyze polycondensation to form firm and impermeable microcapsules, and obtain the present invention. The microcapsule suspension mentioned above.

When the dosage form of the composition is a microcapsule suspension-suspension agent, the auxiliary agents added are surfactants, emulsifiers, solvents, pH regulators, polymer capsule wall materials, defoamers, thickeners, water to 100% .

When the composition is made into a microcapsule suspension-suspension agent, it includes the following components: 1%-60% of active ingredient A, 1%-60% of active ingredient B, 2%-12% of polymer capsule wall material, and 3%-60% of surfactant 15%, organic solvent 1%~5%, emulsifier 1%~6%, defoamer 0.1%~5%, thickener 0.05%~2%, pH regulator 0.1%~5%, water to 100 %.

Using the interfacial polymerization method, mix the active ingredient B, polymer capsule wall material, and organic solvent in the above formula to dissolve into a uniform oil phase, and add the oil phase to the water containing emulsifier and pH regulator under shearing conditions. In the phase solution, the two materials react at the oil-water interface, forming a polymer capsule wall around the droplet containing the chemical substance, and making the active ingredient B microcapsule suspension. Mix the surfactant, defoamer, thickener and antifreeze uniformly under high-speed shearing, add the active ingredient A, and mill in a ball mill for 2 to 3 hours, so that the particle size of all particles is below 5 μm. The active ingredient A suspension is then added to the water phase solution of the active ingredient B microcapsule suspension by dissolving the stable active ingredient A in water to prepare a well-dispersed microcapsule suspension-suspension product of the composition of the present invention.

Described dispersing agent is selected from: alkyl naphthalene sulfonate, double (alkyl) naphthalene sulfonate formaldehyde condensate, naphthalene sulfonate formaldehyde condensate, arylphenol polyoxyethylene succinate sulfonate, octane Alkylphenol polyoxyethylene ether sulfate, polycarboxylate, lignosulfonate, alkylphenol polyoxyethylene pyrimaldehyde condensate sulfate, alkylbenzenesulfonic acid calcium salt, naphthalenesulfonic acid formaldehyde condensate sodium salt , one or more of alkylphenol polyoxyethylene pyrimides, fatty amine polyoxyethylene pyrimides, fatty acid polyoxyethylene esters, and ester polyoxyethylene pyrimides.

The wetting agent is selected from: sodium lauryl sulfate, sodium dodecyl benzene sulfonate, pull open powder BX, washing powder, agricultural milk 2000 ^# series, sodium lauryl sulfate, wetting and penetrating agent F, wetting One or more of agent T, saponin powder, tea Ku, silkworm excrement, and sapindus powder.

The disintegrating agent is selected from one or more of bentonite, urea, ammonium sulfate, aluminum chloride and glucose.

Described emulsifier is selected from: agricultural milk 500 ^# (calcium alkylbenzene sulfonate), OP series phosphate (nonylphenol polyoxyethylene ether phosphate), 600 ^# phosphate (phenylphenol polyoxyethyl ether Phosphate ester), styrene polyoxyethylene ether ammonium sulfate, alkyl diphenyl ether disulfonic acid magnesium salt, triethanolamine salt, agricultural milk 400 ^# (benzyl dimethylphenol polyoxyethyl ether), agricultural milk 600 ^# (phenylphenol polyoxyethyl ether), agricultural milk 700 ^# (alkylphenol formaldehyde resin polyoxyethyl ether), agricultural milk 36 ^# (phenylethylphenol formaldehyde resin polyoxyethyl ether), agricultural milk 1600 ^# (Styrylphenol Polyoxyethyl Polypropylene Ether), Ethylene Oxide-Propylene Oxide Block Copolymer, OP Series (Nonylphenol Polyoxyethylene Ether), By Series (Castor Oil Polyoxyethylene Ether ), Nongru 33 ^# (alkylaryl polyoxypropylene polyoxyethylene ether), Nongru 34 ^# (alkylaryl polyoxyethylene polyoxypropylene ether), Span series (sorbitan monostearate ), Tween series (polyoxyethylene ether of sorbitan fatty acid ester), and one or more of EO series (polyoxyethylene ether of fatty alcohol).

The antifreezing agent is selected from one or more of ethylene glycol, propylene glycol, glycerol and polyethylene glycol.

The defoamer is selected from one or more of silicones, C _8-10 fatty alcohols, C _10-20 saturated fatty acids (such as capric acid), amides, silicone oil, and silicone compounds.

The thickener is selected from one or more of xanthan gum, hydroxymethyl cellulose, hydroxyethyl cellulose, methyl cellulose, magnesium aluminum silicate, and polyvinyl alcohol.

Polymer capsule wall material selection: from urea, formaldehyde, polyisocyanate, multifunctional acyl halide polyamine, multifunctional acyl halide glycol, sodium alginate, polyvinyl alcohol, gelatin, acacia gum, sucrose, modified starch, maltose, One or more of deformed milk protein, glycerin, calcium chloride, carboxymethylcellulose, and β-cyclodextrin.

The filler is selected from one or more of kaolin, diatomite, bentonite, attapulgite, white carbon black, starch, light calcium carbonate, and vegetable oil.

Main technical index of wettable powder of the present invention:

Water-dispersible granule main technical index of the present invention:

Suspending agent main technical index of the present invention:

Suspoemulsion main technical index of the present invention:

Water-emulsion main technical index of the present invention:

Microemulsion main technical index of the present invention:

Main technical index of microcapsule suspension of the present invention:

Microcapsule suspension-suspension agent main technical index of the present invention:

The advantages of the present invention are:

(1) After the compounding of flufenazine, pyridaben, pyridaben, and tebufenpyrad, it has obvious synergistic and sustained effects;

(2) The control spectrum has been expanded, and it is effective against spider mite, yellow spider, rust tick, rust spider, tea yellow mite, cinnabar spider mite, two-spotted Tetranychus urticae, spider mite, Pear psyllids, elm oyster scales, leafhoppers, etc. all have relatively high activity;

(3) Reduce the dosage of pesticides, reduce the residues of pesticides on crops, and reduce environmental pollution;

(4) It is safe for humans and animals, has good environmental compatibility, and is not easy to produce drug resistance.

detailed description

The present invention will be further described below in conjunction with the examples. The percentages in the examples are all percentages by weight, but the present invention is not limited thereto.

Application Example 1

Embodiment 181% flufenazine · pyridaben wettable powder

Flufenazine 1%, pyridaben 80%, alkylnaphthalene sulfonate 5%, saponin powder 3%, kaolin clay added to 100%, the mixture was jet milled to obtain 81% fluorfenazine-pyridaben Wet powder.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Embodiment 260% flufenazine · pyridaben wettable powder

Flufenazin 10%, pyridaben 50%, naphthalenesulfonate formaldehyde condensate sodium salt 6%, sodium lauryl sulfate 4%, bentonite to 100%, the mixture is jet milled to obtain 60% flufenazine · Pyridaben wettable powder.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Embodiment 345% flufenazine · pyridaben wettable powder

Flufenazine 15%, pyridaben 30%, fatty alcohol polyoxyethylene ether 8%, sodium lauryl sulfate 3%, kaolin to 100%, and the mixture is jet milled to obtain 45% fluorfenazin·pyridaben Spirit wettable powder.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Embodiment 461% flufenazine · pyridaben wettable powder

Flufenazine 1%, pyridaben 60%, lignosulfonate 5%, pull-off powder BX 4%, kaolin to 100%, the mixture is jet milled to obtain 61% fluorfenazin·pyridaben wettability powder.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 581% Flufenazine Pyridaben Water-dispersible Granules

Flufenazine 80%, pyridaben 1%, alkylphenol polyoxyethylene pyrimidine 6%, wetting and penetrating agent F5%, urea 2%, white carbon black added to 100%, mixed to obtain 81% flufenazine. Pyridaben water dispersible granules.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 660% Flufenazine Pyridaben Water-dispersible Granules

Flufenazine 20%, pyridaben 40%, sodium lauryl sulfate 4%, arylphenol polyoxyethylene succinate sulfonate 7%, bentonite 2%, kaolin to 100%, mixed to obtain 60% Flufenazine Pyridaben Water-dispersible Granules.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 740% Flufenazine Pyridaben Water-dispersible Granules

Flufenazine 10%, pyridaben 30%, alkylphenol polyoxyethylene pyrimaldehyde condensate sulfate 6%, saponin powder 5%, aluminum chloride 2%, diatomaceous earth to 100%, mixed to prepare 40% Flufenazine Pyridaben Water Dispersible Granules.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 855% Flufenazine Pyridaben Water-dispersible Granules

Add 5% flufenazine, 50% pyridaben, 4% teaku, 7% sodium naphthalenesulfonate formaldehyde condensate, 2% ammonium sulfate, add light calcium carbonate to 100%, and mix to make 55% flufenazine · Pyridaben water dispersible granules.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 945% Flufenazine Pyridaben Suspension Concentrate

Flufenazine 15%, Pyridaben 30%, Polycarboxylate 5%, Sodium Dodecyl Benzene Sulfonate 4%, C _8-10 Fatty Alcohols 1.6%, Phenolic Resin 0.12%, Ethylene Glycol 1.2% 1. Add deionized water to 100%, and mix to prepare 45% flufenazin·pyridaben suspension.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 10 30% Flufenazine Pyridaben Suspension Concentrate

Flufenazine 10%, Pyridaben 20%, Fatty Acid Polyoxyethylene Ester 6%, Tea Cucumber 4%, Silicone Oil 1.2%, Xanthan Gum 0.14%, Glycerin 0.8%, Deionized water added to 100%, mixed A 30% suspension concentrate of flufenazine·pyridaben was prepared.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 11 20% Flufenazine Pyridaben Suspension Concentrate

Flufenazine 5%, Pyridaben 15%, Fatty Alcohol Polyoxyethylene Ether 6%, Sapinberry Powder 3%, C _10-20 Saturated Fatty Acids 2.5%, Xanthan Gum 0.09%, Propylene Glycol 1%, Add ionized water to 100%, and mix to prepare 20% flufenazin·pyridaben suspension.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 12 11% Flufenazine Pyridaben Suspension Concentrate

Flufenazine 10%, pyridaben 1%, alkylphenol polyoxyethylene pyrimaldehyde condensate sulfate 6%, saponin powder 4%, silicone 1.4%, hydroxyethyl cellulose 0.12%, deionized water Add to 100%, and mix to prepare 11% flufenazine-pyridaben suspension.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 13 50% Flufenazine Pyridaben Suspoemulsion

Flufenazine 20%, Pyridaben 30%, Naphthalenesulfonic Acid Formaldehyde Condensate Sodium Salt 5%, Silkworm Excrement 5%, Nonylphenol Polyoxyethylene Ether Phosphate 6%, Propanol 5%, C _8-10 Fat Add 1% of alcohol, 0.08% of polyvinyl alcohol, 1.8% of polyethylene glycol, and deionized water to 100%, and mix to prepare a 50% flufenazine-pyridaben suspoemulsion.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 14 41% Flufenazine Pyridaben Suspoemulsion

Flufenazine 1%, Pyridaben 40%, Naphthalene Sulfonate Formaldehyde Condensate Sodium Salt 5%, Tea Cucumber 4%, Ethylene Oxide-Propylene Oxide Block Copolymer 6%, Butyl Ether 5%, C _{8 ~10} Add 1.2% of fatty alcohols, 0.15% of methylcellulose, 1.6% of propylene glycol, and deionized water to 100%, and mix to prepare 41% flufenazine-pyridaben suspoemulsion.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 15 25% Flufenazine Pyridaben Suspoemulsion

Flufenazine 10%, Pyridaben 15%, Lignosulfonate 6.5%, Sodium Lauryl Sulfate 4%, Sorbitan Fatty Acid Ester Polyoxyethylene Ether 2%, N-Pyrrolidone 5%, C _{8～ 10} Add 0.9% of fatty alcohols, 1.5% of propylene glycol, 0.19% of polyvinyl alcohol, and deionized water to 100%, and mix to prepare 25% flufenazine-pyridaben suspoemulsion.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 16 25% Flufenazine Pyridaben Suspoemulsion

Flufenazine 5%, Pyridaben 20%, Phenylphenol Polyoxyethyl Ether Phosphate 4%, Sodium Lauryl Sulfate 4%, Alkylphenol Polyoxyethylene Pyrim 6%, N-Pyrrolidone 5%, Silicone Oil 0.8 %, 0.17% phenolic resin, 1.6% ethylene glycol, and deionized water to 100%, and mixed to prepare 25% flufenazine·pyridaben suspoemulsion.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Embodiment 1741% flufenazine · pyridaben microemulsion

Flufenazine 40%, Pyridaben 1%, Alkylphenol Formaldehyde Resin Polyoxyethyl Ether 7%, Toluene 4%, Glycerin 1%, Sodium Tripolyphosphate 0.18%, Silicone Oil 1.2%, BHT 2%, Detox Make up 100% with ionized water, and mix to prepare 41% flufenazine·pyridaben microemulsion.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Embodiment 1830% flufenazine · pyridaben microemulsion

Flufenazine 5%, Pyridaben 30%, N-Pyrrolidone 6%, Gum Arabic 0.2%, Styrene Polyoxyethylene Ether Ammonium Sulfate 7%, C _8-10 Fatty Alcohols 1.4%, Triphenyl Phosphite 1.5%, supplemented with deionized water to 100%, to prepare 30% flufenazine·pyridaben microemulsion.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 19 42% Flufenazine Pyridaben Water Emulsion

Flufenazine 2%, Pyridaben 40%, Cyclohexanone 3%, Vegetable Oil 4%, Alkylphenol Formaldehyde Resin Polyoxyethyl Ether 6%, Xanthan Gum 0.18%, Silicones 0.8%, Deionized Water Add to 100%, and mix to prepare 42% flufenazine-pyridaben aqueous emulsion.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 2040% Flufenazine Pyridaben Water Emulsion

Flufenazine 5%, Pyridaben 35%, Ethyl Acetate 3.5%, N-Pyrrolidone 5.5%, Styrene Polyoxyethylene Ether Ammonium Sulfate 7%, Polyethylene Glycol 0.12%, Silicone Compounds 1%, Add deionized water to 100%, and mix to prepare 40% flufenazine-pyridaben aqueous emulsion.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 21 30% Flufenazine Pyridaben Water Emulsion

Flufenazine 15%, Pyridaben 15%, N-pyrrolidone 5%, Cyclohexanone 5%, Alkylaryl polyoxyethylene polyoxypropylene ether 6%, Polyethylene glycol 2%, Hydroxymethyl cellulose 0.14%, C _8-10 fatty alcohols 0.6%, deionized water added to 100%, mixed to prepare 30% flufenazin·pyridaben aqueous emulsion.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 22 25% Flufenazine Pyridaben Water Emulsion

Flufenazine 15%, pyridaben 10%, toluene 7%, phenethylphenol formaldehyde resin polyoxyethyl ether 8%, gum arabic 0.22%, C _8-10 fatty alcohol 1.2%, deionized water added to 100%, 25% flufenazin·pyridaben aqueous emulsion was prepared by mixing.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 23 31% Flufenazine Pyridaben Microcapsule Suspension

Flufenazine 1%, pyridaben 30%, polyisocyanate 3%, polyvinyl alcohol 2%, saponin powder 5%, lignosulfonate 2.4%, toluene 6%, sorbitan fatty acid ester polyoxyethylene Add 5% ether, 0.5% citric acid, 0.6% sodium hydroxide, and deionized water to 100% by weight to prepare a 31% flufenazin·pyridaben microcapsule suspension.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Example 24 21% Flufenazine Pyridaben Microcapsule Suspension-Suspension Concentrate

Flufenazine 20%, pyridaben 1%, glycerin 5%, deformed milk protein 2%, saponin powder 2.5%, ethyl acetate 7%, benzyldimethylphenol polyoxyethyl ether 5%, sorbitol 3% of anhydride monostearate, 0.6% of silicones, 1.2% of gum arabic, 0.4% of sodium hydroxide, 0.8% of citric acid, and water are added to 100% by weight to obtain 21% of flufenazine and pyridaben Microcapsule Suspension - Suspension Concentrate.

A new embodiment is formed by replacing the effective active ingredient pyridaben with propargifen and tebufenpyrad.

Embodiment 2540% flufenazine · tebufenpyrad wettable powder

20% flufenazine, 20% tebufenpyrad, 6% lignosulfonate, 5% saponin powder, add kaolin to 100%, and jet mill the mixture to obtain 40% flufenazine tebufenpyrad wettability powder.

A new embodiment is formed by replacing the effective active ingredient tebufenpyr with propargifen and pyridaben.

Example 26 50% Flufenazine Tebufenpyrad Water-dispersible Granules

10% flufenazine, 40% tebufenpyrad, 4% teaku, 7% fatty acid polyoxyethylene ester, 2% sodium bicarbonate, white carbon black to 100%, mixed to make 50% flufenazine pyrimina Amine water dispersible granules.

A new example is formed by replacing the effective active ingredient tebufenpyr with pyridaben and propargite.

Embodiment 2740% flufenazine · propargite suspension concentrate

Flufenazin 10%, propargite 30%, naphthalenesulfonate formaldehyde condensate sodium salt 7%, sodium lauryl sulfate 3%, C _10-20 saturated fatty acids 1.6%, methylcellulose 0.16%, deionized water Add to 100%, and mix to prepare 40% flufenazine-propargite suspension concentrate.

A new embodiment is formed by replacing the effective active ingredient propargate with pyridaben and tebufenpyr.

Embodiment 28 20% flufenazine · propargite suspoemulsion

Flufenazine 5%, Propargite 15%, Alkylphenol polyoxyethylene pyrimidine 6%, Sapinberry powder 4%, Nonylphenol polyoxyethylene ether phosphate 6%, Propanol 5%, C _10～20 Add 1% of saturated fatty acid, 0.12% of phenolic resin, 1.5% of glycerin, and deionized water to 100%, and mix to prepare 20% of flufenazine-propargite suspoemulsion.

A new embodiment is formed by replacing the effective active ingredient propargate with pyridaben and tebufenpyr.

Embodiment 2920% flufenazine · propargite microemulsion

10% flufenazine, 10% propargite, 6% N-pyrrolidone, 0.2% phenolic resin, 7% sorbitan monostearate, 1.4% silicone compounds, 1.5% triphenyl phosphite, to Make up 100% with ionized water to prepare 20% flufenazine-propargite microemulsion.

A new embodiment is formed by replacing the effective active ingredient propargate with pyridaben and tebufenpyr.

Embodiment 30 25% flufenazine · propargite aqueous emulsion

Flufenazine 10%, propargite 15%, vegetable oil 5%, ethyl acetate 5%, benzyldimethylphenol polyoxyethyl ether 6%, white dextrin 0.18%, silicone 0.8%, deionized Add water to 100%, and mix to prepare 25% flufenazine-propargite aqueous emulsion.

A new embodiment is formed by replacing the effective active ingredient propargate with pyridaben and tebufenpyr.

Embodiment 3145% flufenazine · propargite microcapsule suspension

Flufenazine 15%, propargite 30%, formaldehyde 3%, polyfunctional acyl halide glycol%, saponin powder 5%, alkyl aryl polyoxyethylene ether 2.4%, propanol 5%, fatty alcohol poly Add 5% of oxyethylene ether, 0.5% of sorbic acid, 0.6% of sodium hydroxide, and deionized water to 100% by weight to prepare a 45% flufenazine-propargite microcapsule suspension.

A new embodiment is formed by replacing the effective active ingredient propargate with pyridaben and tebufenpyr.

Example 32 40% flufenazine · propargite microcapsule suspension-suspension agent

Flufenazine 5%, Propargite 35%, Polyisocyanate 5%, Calcium Chloride 4%, Sodium Lauryl Sulfate 2.6%, Vegetable Oil 6%, Phenylphenol Polyoxyethyl Ether 4%, Castor Oil Polyoxyethylene Add 4% ether, 0.8% silicone oil, 1.2% xanthan gum, 0.5% sodium hydroxide, 0.8% hydrochloric acid, and water to 100% by weight to prepare a 40% flufenazine-propargite microcapsule suspension-suspension agent.

A new embodiment is formed by replacing the effective active ingredient propargate with pyridaben and tebufenpyr.

Example 33 40% flufenazine · propargite wettable powder

Flufenazin 10%, propargite 30%, alkylphenol polyoxyethylene pyrimaldehyde condensate sulfate 6%, teaku 5%, kaolin to 100%, the mixture is jet milled to obtain 40% flufenazine · Acetate wettable powder.

A new embodiment is formed by replacing the effective active ingredient propargate with pyridaben and tebufenpyr.

The embodiment of the present invention adopts the method combining indoor virulence determination and field test. The co-toxicity coefficient (CTC) of the two agents after compounding in a certain proportion is clarified first through the indoor toxicity test. CTC<80 is an antagonistic effect, 80≤CTC≤120 is an additive effect, and CTC>120 is a synergistic effect. On this basis, field experiments were carried out.

Test method: During the test, the mother liquor of each compounding agent was diluted into five series of concentrations, and placed in beakers for later use. Using the method of soaking the leaves first and then inoculating them, the leaves of the same size that have not been exposed to any chemical agent are soaked in the prepared medicinal solution for 5 seconds, then taken out, dried naturally, put into the insect breeding box, and then connected with the larvae for testing. Breeding under the condition of 25°C, each treatment was repeated three times, and the number of test insects used in each repetition was 50. At the same time, a blank control was set up, the number of dead insects was checked at 72 hours, the mortality rate and the corrected mortality rate were calculated, and the regression equation of virulence was obtained and calculated. Calculate _LC50 values. If the control mortality rate was greater than 10%, the trial was considered invalid. Calculated as follows:

The pest-corrected mortality rate was converted into a probability value (y), the treatment concentration (μg/ml) was converted into a logarithmic value (x), and the toxicity regression equation was obtained by the least square method, and the value of each pesticide was calculated accordingly. The co-toxicity coefficient CTC was calculated according to Sun Yunpei's formula. The calculation formula is as follows (with flufenazine as the standard agent, its toxicity index is 100):

Theoretical toxicity index (TTI) of M = TI of flufenazine × P of _flufenazine + TI of active ingredient B × P of _{active ingredient B}

In the formula: M is a mixture of different proportions;

P _{Active ingredient B} is the proportion of active ingredient B in the composition;

P _Flufenazine is the proportion of flufenazine in the composition.

Note: Active ingredient B is any one of propargate, pyridaben, and tebufenpyrad.

Application example two:

Pests tested: spider mite.

Experimental design: The effective lethal concentration ranges of flufenazine, pyridaben and their mixtures with different ratios were determined through preliminary experiments.

Toxicity test result one

Table 1 Toxicity determination of different ratios of flufenazine and pyridaben to spider mite

It can be seen from Table 1 that when the combination of flufenazine and pyridaben is 80:1 to 1:80 to prevent and control spider mites, the co-toxicity coefficients are all greater than 120, indicating that the two are mixed within the range of 80:1 to 1:80. The synergistic effect is shown in both formulations, especially when the ratio of flufenazine to pyridaben is 10:1 to 1:20, the synergistic effect is more prominent, and when the weight ratio of flufenazine to pyridaben When the ratio is 1:2, the co-toxicity coefficient is the largest, and the synergistic effect is the most obvious. At the same time, it was found that the ratio of flufenazine to pyridaben was 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1 :1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13 , 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20 when mixed with spider mite, yellow spider, rust tick, rust spider, tea yellow mite, cinnabar leaf Pests such as mite, Tetranychus urticae, Clawed spider mite, pear psyllid, elm oyster scale, leafhopper and other pests also have a good synergistic effect, and the co-toxicity coefficients are all greater than 120.

Application Example Three:

Pests tested: rust tick.

Experimental design: The effective lethal concentration ranges of flufenazine, propargite technical and their mixtures with different ratios were determined through preliminary experiments.

Toxicity test result 2

Table 2 Toxicity determination of different ratios of flufenazine and propargite on rust ticks

It can be seen from Table 2 that when the compounding ratio of flufenazine and propargite to control rust ticks is 80:1 to 1:80, the co-toxicity coefficients are all greater than 120, indicating that the two are in the range of 80:1 to 1:80 Internal mixing all showed synergistic effect, especially when the ratio of flufenazine and propargazite was between 10:1 and 1:30, the synergistic effect was more prominent. When the weight ratio is 1:3, the co-toxicity coefficient is the largest, and the synergistic effect is the most obvious. 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1: 9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:21, 1:22, 1:23, 1:24, 1:25, 1:26, 1:27, 1:28, 1:29, 1:30 when paired with spider mite, yellow spider, rust tick, rust spider Pests such as yellow mite, tea yellow mite, Tetranychus cinnabarinus, Tetranychus urticae, and spider mite also have good synergistic effects, and the co-toxicity coefficients are all greater than 120.

Application example four:

Pests tested: Tetranychus urticae.

Experimental design: The range of effective lethal concentrations of flufenazine, tebufenpyrad and their mixtures with different ratios was determined through preliminary experiments.

Toxicity test results three

Table 3 Toxicity determination of different ratios of flufenazine and tebufenfen against Tetranychus urticae

It can be seen from Table 3 that when the compounding ratio of flufenazine and tebufenfen to prevent and control Tetranychus urticae ranges from 80:1 to 1:80, the co-toxicity coefficients are all greater than 120, indicating that the ratio of the two is 80:1 to 1:80. The synergistic effect is shown in all the mixtures within the range, especially when the ratio of flufenazine and pyrenzafen is from 10:1 to 1:30, the synergistic effect is more prominent. When the weight ratio of amines is 1:3, the co-toxicity coefficient is the largest, and the synergistic effect is the most obvious. At the same time, it is found that the ratio of flufenazine to tebufenpyrad is 10:1, 9:1, 8:1, 7:1, 6: 1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:19 21, 1:22, 1:23, 1:24, 1:25, 1:26, 1:27, 1:28, 1:29, 1:30 when paired with spider mite, yellow spider, rust tick, Pests such as rust spider, tea yellow mite, Tetranychus cinnabarinus, Tetranychus urticae, and Clawed spider mite also have good synergistic effects, and the co-toxicity coefficients are all greater than 120.

Application Example Penflumetazine, Pyridaben and Their Compound Control Efficacy Test on Cotton Tetranychus cinnabarinus

This experiment was arranged in Dali County, Weinan City, Shaanxi Province. The test chemicals were provided by Shaanxi Welch Crop Protection Co., Ltd., and the control drugs were 10% flufenazine suspension concentrate (self-prepared), and 20% pyridaben EC (commercially purchased).

The test adopts the conventional spraying method, investigates the pest index of Tetranychus cinnabarinus before spraying, sprays at the initial stage of pest occurrence, investigates the pest index and calculates the control effect 10 days, 30 days, and 45 days after spraying. The experimental results are as follows:

Table 4 Effect test of flufenazine, pyridaben and their compound on controlling cotton spider mite

It can be seen from Table 4 that the combination of flufenazine and pyridaben can effectively control cotton cinnabarinus, and the control effect is better than that of a single agent, and the effect lasts for a long time. There is no adverse effect on the target crops within the scope of the test drug.

Application Example Hexafluzazin, Propyridine and Their Compounds Control Efficacy Test on Wheat Spider Mite

This experiment was arranged in Liquan County, Xianyang City, Shaanxi Province. The test chemicals were provided by Shaanxi Welch Crop Protection Co., Ltd., and the control drugs were 10% flufenazine suspension concentrate (self-prepared), and 20% propargite emulsifiable concentrate (commercially purchased).

The test adopts the conventional spraying method. The pest index of the wheat leaf mite is investigated before the application of the pesticide, and the pesticide is applied at the initial stage of the pest occurrence. The pest index is investigated 10 days, 30 days, and 45 days after the application, and the control effect is calculated. The experimental results are as follows:

Table 5 Experiments on the efficacy of flufenazine, pyridaben and their compound in the control of wheat spider mite

It can be seen from Table 5 that the combination of flufenazine and propargite can effectively prevent and control spider mite in wheat, and the control effect is better than that of a single agent, and the effect lasts for a long time. There is no adverse effect on the target crops within the scope of the test drug.

Application Example Hexafluzam, Pyridaben and Their Compound Efficacy Test on Controlling Apple Red Spider

This experiment was arranged in Linwei District, Weinan City, Shaanxi Province. The test chemicals were provided by Shaanxi Welch Crop Protection Co., Ltd., and the control drugs were 10% flufenazine suspension concentrate (self-prepared), and 20% pyridaben EC (commercially purchased).

The test adopts the conventional spraying method. The pest index of apple red spider is investigated before the application, and the pesticide is applied at the initial stage of the pest occurrence. The pest index is investigated 10 days, 30 days, and 45 days after the application, and the control effect is calculated. The experimental results are as follows:

Table 6 Effect test of flufenazine, pyridaben and their compound on controlling apple red spider

It can be seen from Table 6 that the combination of flufenazine and pyridaben can effectively control apple spider mite, and the control effect is better than that of a single agent, and the effect lasts for a long time. There is no adverse effect on the target crops within the scope of the test drug.

Application Example: Steflufenazine, Tebufenpyrad and Their Compounds Control Efficacy of Citrus Rust Tick

This experiment was arranged in Haiyan County, Jiaxing City, Zhejiang Province. The test chemicals were provided by Shaanxi Welch Crop Protection Co., Ltd. The control drugs were 10% flufenazine suspension concentrate (self-prepared), 20% tebufenfen wettable powder (self-prepared) .

The conventional spraying method was used in the test. The pest index of citrus rust tick was investigated before the application, and the pesticide was applied at the initial stage of the pest occurrence. The pest index was investigated 10 days, 30 days, and 45 days after the application, and the control effect was calculated. The experimental results are as follows:

Table 7 Effect test of flufenazine, tebufenfen and their compound on controlling citrus rust tick

It can be seen from Table 7 that the combination of flufenazine and tebufenpyrad can effectively control citrus rust ticks, and the control effect is better than that of a single agent, and the effect lasts for a long time. There is no adverse effect on the target crops within the scope of the test drug.

Application Example Nonafluzam, Propyridine and Their Compound Efficacy Test on Controlling Citrus Spider Mite

This experiment was arranged in Haiyan County, Jiaxing City, Zhejiang Province. The test chemicals were provided by Shaanxi Welch Crop Protection Co., Ltd. The control drugs were 10% flufenazine suspension concentrate (self-prepared), 20% tebufenfen wettable powder (self-prepared) .

The conventional spraying method was used in the test. The pest index of citrus spider mite was investigated before spraying, and the pesticide was applied at the initial stage of pest occurrence. The pest index was investigated 10 days, 30 days, and 45 days after spraying, and the control effect was calculated. The experimental results are as follows:

Table 8 Effect test of flufenazine, tebufenpyrad and their compound on controlling citrus spider mite

It can be seen from Table 8 that the combination of flufenazine and tebufenpyrad can effectively control citrus spider mite, and the control effect is better than that of a single agent, and the effect lasts for a long time. There is no adverse effect on the target crops within the scope of the test drug.

After tests in different places across the country, it was found that flufenazine was compounded with pyridaben, propyzafen, and tebufenpyrad to form wettable powders, water-dispersible granules, suspensions, suspoemulsions, emulsions in water, and microemulsions. , microcapsule suspension, microcapsule suspension-suspended agent, after the suspension of all kinds of crops, such as spider mite, yellow spider, rust tick, rust spider, tea yellow mite, cinnabarinite, two-spotted spider mite, spider mite and other common The pest control efficiency is above 95%, which is better than that of a single agent, and the synergistic effect is obvious.

Claims (8)

1. the Pesticidal combination containing fluorine mite piperazine, effective active composition is active components A, active component B, it is characterized in that: active components A is fluorine mite piperazine, active component B is arbitrary a kind of in pyridaben, propargite, tebufenpyrad, and the weight ratio of active components A and active component B is 1 ︰ 80 ~ 80 ︰ 1.

2. the Pesticidal combination containing fluorine mite piperazine according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 60 ~ 40 ︰ 1.

3. the Pesticidal combination containing fluorine mite piperazine according to claim 2, is characterized in that: the weight ratio of fluorine mite piperazine and pyridaben is 1 ︰ 40 ~ 20 ︰ 1.

4. the Pesticidal combination containing fluorine mite piperazine according to claim 2, is characterized in that: the weight ratio of fluorine mite piperazine and propargite is 1 ︰ 30 ~ 10 ︰ 1.

5. the Pesticidal combination containing fluorine mite piperazine according to claim 2, is characterized in that: the weight ratio of fluorine mite piperazine and tebufenpyrad is 1 ︰ 30 ~ 10 ︰ 1.

6., according to the Pesticidal combination containing fluorine mite piperazine in claim 1 ~ 5 described in any one, it is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.

7. the Pesticidal combination containing fluorine mite piperazine according to claim 6 is for preventing and treating the application of insect on wheat, cotton, fruit tree, vegetables, tea tree.

8. application according to claim 7, is characterized in that described insect is two spotted spider mite, yellow spider, blister mite, yellow tea mite, pear sucker, oystershell scale, leafhopper.