CN102813897A - Preparation method of traditional Chinese medicine for treating insomnia type acute glomerulonephritis - Google Patents

Abstract

The invention relates to a preparation method of a traditional Chinese medicine for treating insomnia type acute glomerulonephritis, belonging to the technical field of preparation methods of traditional Chinese medicines. At present, penicillin is generally adopted for treating insomnia type acute glomerulonephritis, but penicillin can easily cause allergic reaction, and especially allergic shock. The technical scheme adopted in the invention is as follows: taking ossa draconis, concha ostreae, fluorite fluoritum, spina date seed, platycladi seed, polygala tenuifolia, cortex albiziae, tuber fleeceflower stem, valerian, fushen, radix pseudostellariae, black-bone chicken, cabbage, arillus longan, bighead atractylodes rhizome, radix paeoniae alba, American ginseng, angelica sinensis, lotus seed, codonopsis pilosula, sharpleaf galangal fruit, astragalus mongholicus, solomon's seal, polished round-grained rice, rhizome zingiberis, wheat and liquorice, soaking the 27 kinds of traditional Chinese medicines in water, and decocting with slow fire, wherein the decocted liquid medicine is the traditional Chinese medicine for treating insomnia type acute glomerulonephritis. The prepared traditional Chinese liquid medicine has the advantages of short course of treatment and high cure rate. Assistant and guide are achieved so that the function is just right. When the traditional Chinese medicine for treating insomnia type acute glomerulonephritis is applied, adverse reaction, allergic reaction and toxic reaction caused by Western medicine are avoided.

Description

The be insomnia Chinese medicinal preparation method of type acute glomerulonephritis of a kind of treatment

Technical field

The present invention relates to the Chinese medicinal preparation method technical field, is the be insomnia Chinese medicinal preparation method of type acute glomerulonephritis of a kind of treatment more specifically.

Background technology

The type acute glomerulonephritis of being insomnia of treatment at present, the general employing: 1, penicillin: these article are prone to take place allergy, the particularly anaphylactic shock (anaphylactic shock of danger; Can occur in and do tuerculoderma at that time, only a few can occur in the continuous use process, the Delayed Hypersensitivity shock); Like untimely rescue; Can critical life, thus all to improve protection before, during and after the medication, so as to avoid an accident.Attention: before the application, must ask to have or not anaphylactic disease clearly,, must do the penicillin skin test earlier with having or not allergy such as erythra, heating to occur behind the penicillin.2, amoxicillin: accidental erythra, oral can have nauseating, epigastric discomfort, diarrhoea etc. after a large amount of; Pseudomembranous colitis.3, carbenicillin: various types of allergy can occur.Possibly cause neural poison reaction, pulmonary edema after heavy dose of administration, possibly occur the transience transaminase during the medication and raise and granulocytopenia.4, reserpine: nasal obstruction, gastric acid secretion increase, times of defecation increases and aroused in interest slack-off etc., even apathetic expression can appear in long-term extensive application, drowsiness, spirit depressing causes EPS, the performance muscular tremor.1. to activeness Peptic Ulcers and dysthymia person's forbidding; 2. reserpine can get into fetal tissue through Placenta Hominis, if the antenatal application of anemia of pregnant woman can cause neonate nasal obstruction, respiratory tract obstruction, should try one's best need not.5, hydrochlorothiazide: the low blood chlorine of 1. hypokalemia, and normal companion, hypomagnesemia, hypokalemia can bring out hepatic coma and Folium Digitalis Purpureae institute proarrhythmia, needs timely kalium replenishment or add to stay the potassium diuretic; 2. hyperglycemia reduces carbohydrate tolerance; 3. symptom can brought out or increase the weight of to hyperuricemia to the goat image; 4. azotemia because of reducing glomerular filtration rate, increases the weight of azotemia and renal function is further worsened the renal insufficiency patient, and these article diuretic effect is poor, so careful usefulness of renal failure patient or forbidding; 5. ammonirrhea reduces, and possibly the H+ secretion reduced because of suppressing carbonic anhydrase, and the ammonia secretion also reduces.During hepatic disfunction, can bring out hepatic coma; 6. parathyroid gland effect: take for a long time and can cause hypercalcemia, low serum p disease and parathyroid hyperplasia; 7. other: skin erythema, photoallergic dermatitis, pancreatitis, intrahepatic cholestasis, bone marrow depression, especially thrombocytopenia can cause the announcements that all appear in the newspapers such as purpura, neutrophilic granulocyte minimizing, hemolytic anemia of newborn, the serum anti antinuclear antibodies positive.6, bendazol: headache, hyperhidrosis, heating sense are arranged.7, captopril: important side effect is Toxicity of Kidney and granulocytopenia, is erythra, dysgeusia and cough secondly.Heavy dose can cause hemodynamic change, symptomatic hypotension etc.

Summary of the invention

For overcoming above-mentioned shortcoming, the objective of the invention is to invent the be insomnia Chinese medicinal preparation method of type acute glomerulonephritis of a kind of treatment.Acute glomerulonephritis is called for short acute nephritis, is one group of common glomerule illness.Onset is anxious, is its Clinical symptoms with hematuria, oliguria, albuminuria, edema and hypertension etc.Acute nephritis can be because of due to the Different types of etiopathogenises, and wherein modal is post-streptococcal infection nephritis, and other causes of disease still have antibacterial (like staphylococcus), virus (like hepatitis B virus), protozoon (like plasmodium) etc.Primary disease belongs to " edema due to wind pathogen ", the category of " YANG edema " and " hematuria " in the Chinese medicine " edema ".

Etiology and pathogenesis: anxiousThe property glomerulonephritis is a main clinical manifestation with hematuria, edema,proteinuria,hypertension.Human liquid's metabolism relies on the logical of lung qi to transfer, the transferring of temper, and opening of kidney qi is entire, thereby makes its duty of certainly showing disrespect on of three warmers performance.Ailment said due to cold or exposure, water are wet in order to experience for the primary disease cause of disease, noxious dampness, damp and hot heresy, invasion and attack flesh table, and internal injury is in lung, impairment of dispersing and descending function of the lung; Or in belong to spleen, spleen loses fortuneization; Under injure kidney, kidney loses folding, disturbance in water passage then, and be edema.In the acute nephritis edema stage, the main diseases position is main at lung, spleen with inhibited pulmonary QI.If hematuria is obvious, how by the damp-heat accumulation bladder, injury of blood collaterals by heat is due to venation is impaired.If the intenseness of heat wind symptom, disturb sun clearly on the wind-fire, dizziness headache then appears, even the evil cards of violating conscience such as convulsions, coma.Spleen-QI failing to rise up, deficiency of kidney-QI, smart closing admittedly, albuminuria then appears in the separating clear and excreting turbid dereliction of duty.So the sick position of primary disease is dirty at lung, spleen, kidney three, syndrome develop be from table and in, reach the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels by the part of the body cavity above the diaphragm housing the heart and lungs, middle Jiao, develop to simulataneous insufficiency and excessive from real.Heart and gallbladder void is timid, and the state of mind is uneasy: the empty timid people of heart and gallbladder, and susceptible to fright and fear, so that the state of mind is uneasy, and for being insomnia.Or frightened cruelly, nervous, fear all day, gradually be insomnia to timidness due to deficiency of the heart.

Clinical manifestation:Cardiopalmus is insomnia, and the middle dream of sleeping is many, touches thing and is prone to frightened.Onset is more anxious, and state of an illness weight does not wait.Most of patients has clear and definite streptococcal infection history, like upper respiratory tract infection, pharyngitis, tonsillitis and skin infection etc.Sudden onset, mostly first symptom is edema and hematuria.1, edema: the lighter only plays blepharoedema morning, and complexion is paler, is " nephritis face ".Weight person prolongs and whole body, and finger pressure skin can not have significant depressions, and body weight also increases thereupon.2, hypertension: be shown in 80% case, be mostly light moderate hypertension, diastolic pressure is less than 14kpa.Mostly the hypertension of acute nephritis is a property crossed, and the generation reason is mainly water, sodium retention makes due to the blood volume expansion.3, urine is unusual: 1. oliguria: the most of patients onset has oliguria often, as every day the urine amount be less than 500ml person, but the had slight azotemia.2. hematuria: be shown in all acute nephritis patients, can be gross hematuria, or muddy coffee-like, general persistence is not long, promptly transfers microscopic hematuria to.3. albuminuria: most of patients all has 4. whole body performance of albuminuria in various degree: tired, lumbago, anorexia, feel sick, vomiting, the person of being in a bad way can have headache, dizziness, drowsiness, blurred vision etc.Pale tongue, tongue is white, stringy and thready pulse.

Its technical scheme is:Get Os Draconis 6 weight portions, Concha Ostreae 9 weight portions, Fluoritum 3 weight portions, Semen Ziziphi Spinosae 9 weight portions, Semen Platycladi 3 weight portions, Radix Polygalae 3 weight portions, Cortex Albiziae 6 weight portions, Caulis Polygoni Multiflori 3 weight portions, Rhizoma et radix valerianae 9 weight portions, Poria cum Radix Pini's 9 weight portions, Radix Pseudostellariae 9 weight portions, Gallus Domesticus 9 weight portions, Caulis et Folium Brassicae capitatae 6 weight portions, Arillus Longan 6 weight portions, the Rhizoma Atractylodis Macrocephalae 6 weight portions, Radix Paeoniae Alba 9 weight portions, Radix Panacis Quinquefolii 3 weight portions, Radix Angelicae Sinensis 3 weight portions, Semen Nelumbinis 6 weight portions, Radix Codonopsis 6 weight portions, Fructus Alpiniae Oxyphyllae 3 weight portions, the Radix Astragali 3 weight portions, Rhizoma Polygonati 6 weight portions, Semen oryzae sativae 9 weight portions, Rhizoma Zingiberis 3 weight portions, Semen Tritici aestivi 9 weight portions and Radix Glycyrrhizae 9 weight portions; Above 27 flavor Chinese medicines are put into 1800 ml waters; Soaked 35 minutes; Slow fire is fried 30 minutes then; Boil medicine altogether 390 milliliters of liquid of filter and remove residue, fried medicinal liquid are the be insomnia Chinese medicine of type acute glomerulonephritis of treatment.

The advantage of this invention is:We's 27 flavor Chinese medicines all can have been bought in pharmacy, make simply, and the herb liquid toxic and side effects of processing is little, short treating period, and cure rate is high.Monarch, just right.When using Chinese medicine, untoward reaction, anaphylaxis and the toxic reaction of having avoided Western medicine to cause.Os Draconis, Concha Ostreae, Fluoritum, Semen Ziziphi Spinosae, Semen Platycladi, Radix Polygalae, Cortex Albiziae, Caulis Polygoni Multiflori, Rhizoma et radix valerianae, Poria cum Radix Pini, more than 10 the flavor medical instruments tranquillizing the mind by relieving convulsion is arranged, suppressing the hyperactive liver and subsiding YANG, the warming the lung therapeutic method to keep the adverse QI flowing downwards; Tranquilizing by nourishing the heart, loosening bowel to relieve constipation dispels the wind and controls numbness; The edema detoxifcation, the antitussive that eliminates the phlegm, the sharp diaphragm of resolving depression; The appetizing of regulating the flow of vital energy, dispelling cold by warming the meridian, tonify deficiency are controlled the effect of labor.In the process of type acute glomerulonephritis is insomnia in treatment, play main therapeutical effect, so be monarch drug.Radix Pseudostellariae, Gallus Domesticus, Caulis et Folium Brassicae capitatae, Arillus Longan, the Rhizoma Atractylodis Macrocephalae, Radix Paeoniae Alba, Radix Panacis Quinquefolii, Radix Angelicae Sinensis, Semen Nelumbinis, Radix Codonopsis, Fructus Alpiniae Oxyphyllae, the Radix Astragali, Rhizoma Polygonati, Semen oryzae sativae, Rhizoma Zingiberis, more than 15 flavor medical instruments the effect of QI invigorating emergency treatment of collapse, strengthening the spleen and nourishing the stomach, warm spleen cold expelling, invigorating the spleen and replenishing QI is arranged.In the process of type acute glomerulonephritis is insomnia in treatment, can assist principal agent performance therapeutical effect, so be ministerial drug.Semen Tritici aestivi: sweet, cold.Go into the heart, spleen, kidney three warps.Strengthening the spleen, clearing heat and moistening dryness, styptic powder blood nourish heart.The through focus of all medicines of energy rate is so be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.The bias of all medicines can be entangled, the toxicity of all medicines can be alleviated again, so be messenger drug.Os Draconis, Concha Ostreae, Fluoritum, Semen Ziziphi Spinosae, Semen Platycladi, Radix Polygalae, Cortex Albiziae, Caulis Polygoni Multiflori, Rhizoma et radix valerianae, Poria cum Radix Pini, Radix Pseudostellariae, Gallus Domesticus, Caulis et Folium Brassicae capitatae, Arillus Longan, the Rhizoma Atractylodis Macrocephalae, Radix Paeoniae Alba, Radix Panacis Quinquefolii, Radix Angelicae Sinensis, Semen Nelumbinis, Radix Codonopsis, Fructus Alpiniae Oxyphyllae, the Radix Astragali, Rhizoma Polygonati, Semen oryzae sativae, Rhizoma Zingiberis, Semen Tritici aestivi, Radix Glycyrrhizae; This 27 flavor medicine compatibility is used, the effect of play QI invigorating emergency treatment of collapse, strengthening the spleen and nourishing the stomach, warm spleen cold expelling, invigorating the spleen and replenishing QI, invigorating the liver and kidney, promoting blood circulation and stopping pain, yin fluid astringing, easing the affected liver to relieve pain, yin nourishing suppressing the hyperactive liver jointly, calming the nerves.Monarch, compatibility is proper, is the optimum formula of treating the type acute glomerulonephritis of being insomnia.Os Draconis: sweet, puckery, be slightly cold.Go into the heart, liver, kidney, large intestine four warps.Tranquillizing the mind by relieving convulsion, suppressing the hyperactive liver and subsiding YANG, restrain astringent or styptic treatment for spontaneous sweating, promoting tissue regeneration and ulcer healing, removing dampness is held back skin ulcer.Concha Ostreae: salty, puckery, cold.Go into liver, kidney two warps.Restrain astringent or styptic treatment for spontaneous sweating, heat clearing away tonifying YIN, yin fluid astringing YANG hyperactivity suppressing, softening and eliminating sputum.Fluoritum: sweet, temperature.Go into the heart, liver two warps.The relieving palpitation arresting convulsion, the warming the lung therapeutic method to keep the adverse QI flowing downwards, beneficial blood warms up the palace.Semen Ziziphi Spinosae: sweet, sour, flat.Go into the heart, spleen, liver, gallbladder four warps.Tranquilizing by nourishing the heart, astringing YIN to stop sweating.Semen Platycladi: sweet, flat.Go into the heart, liver, spleen three warps.Tranquilizing by nourishing the heart, tonifying YIN nourishes blood, loosening bowel to relieve constipation, astringing to arrest bleeding dispels the wind and controls numbness.Radix Polygalae: bitter, hot, temperature.Go into the heart, kidney, spleen three warps.Restoring normal coordination between the heart and kidney is calmed the nerves and is nourished heart, edema detoxifcation, the antitussive that eliminates the phlegm, the sharp diaphragm of resolving depression.Cortex Albiziae: sweet, flat.Go into the heart, liver, spleen three warps.Resolving stagnation for tranquilization, the appetizing of regulating the flow of vital energy, activating collaterals to relieve pain.Caulis Polygoni Multiflori: sweet, little hardship, flat.Go into the heart, spleen, liver, kidney four warps.Tranquilizing by nourishing the heart, dispelling wind and removing obstruction in the collateral, carbuncle scrofula, wind skin ulcer scabies.Rhizoma et radix valerianae: hot, bitter, temperature has little poison.Go into the heart, liver two warps.Tranquillizing and allaying excitement, blood circulation promoting and blood stasis dispelling, dispelling cold by warming the meridian, urine sudden profuse uterine bleeding.Poria cum Radix Pini: sweet, light, flat.Go into the heart, spleen two warps.Tranquilizing by nourishing the heart, inducing diuresis to remove edema, tonify deficiency is controlled labor.Radix Pseudostellariae: sweet, little hardship, tepor.Go into spleen, lung two warps.Mend strengthening spleen and lung, supplementing QI for promoting the production of body fluid.Gallus Domesticus: sweet, flat.Go into liver, kidney two warps.Yin nourishing is brought down a fever.Caulis et Folium Brassicae capitatae: sweet, flat, nontoxic.Go into stomach, kidney two warps.Benefit kidney and replenishing marrow and stomach and alleviating pain.Arillus Longan: sweet, warm.Go into the heart, spleen two warps.Invigorating the heart and spleen, nourishing blood to tranquillize the mind, nourishing the lung to arrest cough.The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.Go into spleen, stomach two warps.Air making-up and spleen enlivening, drying dampness to eliminate phlegm, diuretic detumescent, expelling wind and cold, strengthening superficial resistance to stop perspiration, QI invigorating are antiabortive.Radix Paeoniae Alba: bitter, sour, be slightly cold.Go into liver, spleen two warps.Nourishing blood to suppress the hyperactive liver, astringing YIN to stop sweating, slow middle pain relieving, suppressing liver-YANG.Radix Panacis Quinquefolii: hot, sweet, bitter, cold.Go into the heart, lung, stomach, kidney, the large intestine Five Classics.QI invigorating tonifying YIN, clearing away heat and promoting production of body fluid, clearing away heat to stop bleeding.Radix Angelicae Sinensis: hot, sweet, temperature.Go into the heart, liver, spleen, lung four warps.Nourish blood and blood, promoting blood circulation and stopping pain, nourishing blood for regulating menstruation, loosening bowel to relieve constipation, sending down the abnormal ascending QI cough-relieving treatment headache, fever due to internal injury.Semen Nelumbinis: sweet, puckery, flat.Go into the heart, spleen, kidney three warps.Spleen reinforcing antidiarrheal, kidney tonifying end something lost, tranquilizing by nourishing the heart.Radix Codonopsis: sweet, flat.Go into lung, spleen two warps.Replenishing QI to invigorate the spleen, supplementing QI for promoting the production of body fluid, QI invigorating heat extraction.Fructus Alpiniae Oxyphyllae: suffering, temperature.Go into spleen, stomach two warps.Warm spleen cold expelling, the kidney warming tonify deficiency.The Radix Astragali: sweet, tepor, nontoxic.Go into lung, spleen two warps.Tonifying Qi and lifting yang, hemostasis by invigorating QI, QI invigorating row stagnate, blood stasis removing eliminating stagnation, benefiting QI for strengthening the superficies, QI invigorating tonifying YIN, inducing diuresis to remove edema, warming the interior cold expelling, pus expelling by strengthening vital QI granulation promoting, strong body constitution, life lengthening.Rhizoma Polygonati: sweet, flat, nontoxic.Go into spleen, lung, kidney three warps.Control deficiency of lung-YIN cough, control pulmonary tuberculosis hemoptysis, beneficial able-bodied muscles and bones, control interior-heat and quench one's thirst, control weakness of the spleen and stomach.Semen oryzae sativae: sweet, flat.Go into spleen, stomach two warps.Invigorating the spleen and replenishing QI, invigorating spleen to remove dampness.Rhizoma Zingiberis: hot, hot.Go into spleen, stomach, lung three warps.Warming middle-JIAO by cold, recuperating depleted YANG is promoted blood circulation, the expectorant therapeutic method to keep the adverse QI flowing downwards, warming the lung to resolve fluid-retention, warming the meridian for stopping bleeding, control carbuncle from the beginning of.Semen Tritici aestivi: sweet, cold.Go into the heart, spleen, kidney three warps.Strengthening the spleen, clearing heat and moistening dryness, styptic powder blood nourish heart.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.

The specific embodiment

Get Os Draconis 6g, Concha Ostreae 9g, Fluoritum 3g, Semen Ziziphi Spinosae 9g, Semen Platycladi 3g, Radix Polygalae 3g, Cortex Albiziae 6g, Caulis Polygoni Multiflori 3g, Rhizoma et radix valerianae 9g, Poria cum Radix Pini 9g, Radix Pseudostellariae 9g, Gallus Domesticus 9g, Caulis et Folium Brassicae capitatae 6g, Arillus Longan 6g, Rhizoma Atractylodis Macrocephalae 6g, Radix Paeoniae Alba 9g, Radix Panacis Quinquefolii 3g, Radix Angelicae Sinensis 3g, Semen Nelumbinis 6g, Radix Codonopsis 6g, Fructus Alpiniae Oxyphyllae 3g, Radix Astragali 3g, Rhizoma Polygonati 6g, Semen oryzae sativae 9g, Rhizoma Zingiberis 3g, Semen Tritici aestivi 9g and Radix Glycyrrhizae 9g; More than 27 the flavor medicines put into 1800 ml waters together; Soaked 35 minutes; Slow fire is fried 30 minutes then; Filter and remove residue, fried medicinal liquid are the Chinese medicine of treating the type acute glomerulonephritis of being insomnia.Boil medicine altogether 390 milliliters of liquid, when the patient of the type acute glomerulonephritis of being insomnia need treat, making fluid temperature was 36 ℃, each 130 milliliters, oral, every day three times, two is a course of treatment, if symptom is still deposited, obeys for second course of treatment again, so that recovery from illness.

359 examples are insomnia among the type acute glomerulonephritis patient, and male's 178 examples account for 49.58%; Women's 181 examples account for 50.42%.The women is more than the male.

Table one, the 359 examples type acute glomerulonephritis patient's age scope of being insomnia

Age (year)	18～20	21～30	31～50	51～60
					The example number	17	169	168	5
Percentage ratio	4.73%	47.08%	46.8%	1.39%

Table two, the 359 examples type acute glomerulonephritis patient curative effect table of being insomnia

Curative effect	Cure	Take a turn for the better	Invalid
				The example number	356	3	Do not have
Percentage ratio	99.16%	0.84%	Do not have

The type acute glomerulonephritis patient that is insomnia shows the course of treatment for table three, 359 examples

The treatment natural law	3～5	6～9	10～15	16～18
					The example number	12	265	79	3
Percentage ratio	3.34%	73.82%	22.0%	0.84%

Table four, the 359 examples information slip before and after the type acute glomerulonephritis patient treatment of being insomnia

Claims (1)

1. the treatment Chinese medicinal preparation method of type acute glomerulonephritis of being insomnia; It is characterized in that: get Os Draconis 6 gram, Concha Ostreae 9 grams, Fluoritum 3 grams, Semen Ziziphi Spinosae 9 grams, Semen Platycladi 3 grams, Radix Polygalae 3 grams, Cortex Albiziae 6 grams, Caulis Polygoni Multiflori 3 grams, Rhizoma et radix valerianae 9 grams, Poria cum Radix Pini's 9 grams, Radix Pseudostellariae 9 grams, Gallus Domesticus 9 grams, Caulis et Folium Brassicae capitatae 6 grams, Arillus Longan 6 grams, the Rhizoma Atractylodis Macrocephalae 6 grams, Radix Paeoniae Alba 9 grams, Radix Panacis Quinquefolii 3 grams, Radix Angelicae Sinensis 3 grams, Semen Nelumbinis 6 grams, Radix Codonopsis 6 grams, Fructus Alpiniae Oxyphyllae 3 grams, the Radix Astragali 3 grams, Rhizoma Polygonati 6 grams, Semen oryzae sativae 9 grams, Rhizoma Zingiberis 3 grams, Semen Tritici aestivi 9 gram and Radix Glycyrrhizae 9 gram; Above 27 flavor Chinese medicines are put into 1800 ml waters; Soaked 35 minutes; Slow fire is fried 30 minutes then; Boil medicine altogether 390 milliliters of liquid of filter and remove residue, fried medicinal liquid are the be insomnia Chinese medicine of type acute glomerulonephritis of treatment.