CN102813064A - Plant extract feed additive for piglets - Google Patents
Plant extract feed additive for piglets Download PDFInfo
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- CN102813064A CN102813064A CN2012103409389A CN201210340938A CN102813064A CN 102813064 A CN102813064 A CN 102813064A CN 2012103409389 A CN2012103409389 A CN 2012103409389A CN 201210340938 A CN201210340938 A CN 201210340938A CN 102813064 A CN102813064 A CN 102813064A
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- extract
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- micro mist
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a compound feed additive which is prepared by compounding hawthorn powder, portulaca oleracea herb micro powder, honeysuckle extract, dandelion extract, grape seed extract, echinacea extract, astragalus extract, common andrographis herb extract, numerous types of plant materials subjected to ultramicro grinding or extracting. The plant extract feed additive is prepared by selecting natural plants through the processes of micro grinding, extracting, concentrating and the like, and has the characteristics of wide raw material sources, high biological utilization rate, no toxicity and no residue, and antibiotics are prevented from being accumulated in the livestock body at the source. The compound feed additive can obviously reduce the piglet diarrhea which is caused by various reasons, the daily increased weight of the piglet is increased, and the humoral immunity and cell immunity functions of the piglet are improved.
Description
Technical field
The present invention relates to a kind of pig feed additive, particularly relate to the newborn piglet that a kind of natural plant extracts reasonable formula develops and use feed addictive.
Background technology
Antibiotic feed additive has played important contribution in the development course in 30 years of China's feed industry, it has played huge impetus to prevention livestock and poultry, raising production performance and increase economic benefit.But the appearance of antibiotic residues in animal-derived food and superbacteria has in recent years caused world wide interior concern and worry to feed safety and food-safety problem.
The long-term a large amount of antibiotic that add on the one hand can be residual in animal products, causes antibiotic in human body, to be accumulated, and causes allergic reaction, the side effect of allergy, flora imbalance; Also there are simultaneously teratogenesis, carcinogenic, mutagenesis risk; Antibiotic is discharged in the environment and residual in animals and plants and environment through feces of livestock and poultry; The enrichment of food chain can make these left drugs finally get in the human body, and the microorganism in the environment also can produce drug resistance through coercive selection effect.
Control newborn grice diarrhoea is the key subjects that pig industry faces in the world wide always.Only healthy from the protection pig, enhance productivity, the angle of environmental protection and food security, released the substitute products of antibiotic feed additive both at home and abroad successively, like enzyme preparation, acidulant, probiotics etc.But because there is the defective of manufacturing technique requirent height and thermal instability in enzyme preparation; Acidulant exists additive capacity to have corrosive defective greatly and to machinery equipment; Aspect defectives such as probiotics exists production technology imperfection, quality standard disunity, storage requirement is not up to standard and thermo-labile; Make and differ greatly these product result of use less stables from applying on a large scale.
Plant extract feed additive is a natural materials, and toxic and side effect is little, is difficult for developing immunity to drugs, and residual quantity is low, does not receive Influence of Temperature in the feed processing technology in the use.Have in recent years the scholar to plant extracts the application on livestock and poultry carried out some researchs, for example allicin is being used in the fowl feed as the antibiotic growth promoting substance of bird, ends dysentery grass extract and in pig feed, adds use as antibiotic growth promoting substance.But the anti diar rhea effect of these single extracts is difficult to compare favourably with antibiotic.Therefore, control newborn grice diarrhoea at present and remain heavy dose of interpolation antibiotic, or add antibiotic and antibiotic substitute simultaneously, fundamentally do not eliminate the risk hidden danger of Antibiotic Additive.Therefore, the inventor attempts the plant extracts of multiple integration of drinking and medicinal herbs is carried out the reasonable formula proportioning through a large amount of experiments, and a kind of new type compound plant extract feed additive with noresidue, nuisanceless, safety, environmental protection characteristic finally is provided.
Summary of the invention
The object of the invention be to provide have noresidue, the new type compound plant extract feed additive of nuisanceless, safety, environmental protection characteristic.
The present invention is according to the floristics of the integration of drinking and medicinal herbs of health ministry regulation; Filter out Fructus Crataegi micropowder, purslane herb micro mist, Honegsukle flower P.E, dandelion extract, grape seed extract, Echinacea Purpurea Herb P.E, Astragalus Root P.E, the broken or extract of several plant ultra-micropowders of Andrographis Paniculata; Through reasonable formula, a kind of new type compound plant extract feed additive with noresidue, nuisanceless, safety, environmental protection characteristic is provided finally.Hawthorn has that the having indigestion of disappearing is good for the stomach, anti-cancer, anticancer, cardiac stimulant, reducing blood lipid, hypotensive, the multiple effects such as hemostasis, anti-inflammation, expelling tenia of loosing; That purslane herb micro mist has is clearing heat and detoxicating, Li Shui dries, the blood detumescence of loosing, dedusting sterilization, anti-inflammatory analgetic, hemostasis cold blood, antianaphylactic function; The principal component chlorogenic acid has effect antibiotic and the enhancing body immunocompetence in the Honegsukle flower P.E, and many bacteriums are all had inhibitory action, therefore has the good curing effect for bacterial diarrhea; The former blue and white element of principal component has anti-oxidant, anti-inflammatory, antipathogen in the grape seed extract, function such as stimulate circulation; Active ingredient flavones (Flavonoids) in the dandelion extract; The function that taraxasterol (Taraxasterols) etc. has is clearing heat and detoxicating, joint, promoting diuresis for stranguria are loose in detumescence; Particularly the suppuration bacterium is had unique effect, some virus, fungi and Leptospira are also had inhibitory action; Herba Andrographitis has four kinds of lactone compositions, i.e. deoxyandrographolide, andrographolide, neoandrographolide and Dehydro and drographolide; Andrographolide is the clinical composition that generally uses with total lactone, has hypocatharsis, cures the wound antimalarial; Anti-inflammatory, eliminating phlegm, the physiological function of purification; Cichoric acid in the Echinacea, Echinacea purpurea glucoside, glycoprotein, caffeic acid derivative, alkylamide, flavones, alkaloid, resin, aliphatic acid etc. all have very significantly directly medicinal function, and Echinacea has the human body cell of significantly improving immunity and humoral immunity, antiviral, anti-oxidant, Green Tea Extract, inhibition tumour, antiinflammatory action.Astragalus polyose has the body of promotion to some virus, parasite specificity and non-specific immune function, but enhancing body is to the ability of virus induction interferon;
Technical scheme of the present invention is to be main agent with Honegsukle flower P.E, dandelion extract, grape seed extract, Andrographis Paniculata, purslane herb ultramicro grinding thing, hawthorn ultramicro grinding thing; Through opposing encountered pathogenic bacteria, reduction allergic reaction, reach the diarrhoea effect that control bacterium, fungi and trophism antigen cause; With Echinacea Purpurea Herb P.E, Astragalus Root P.E is the secondary role thing, through improving the nospecific immunity function of body, reaches the effect of strengthening body opposing cause of disease.This compound additive makes an addition to piglet feed as the substitute of antibiotic feed additive, can reduce newborn grice diarrhoea, improves daily gain, the enhance immunity function.
The invention provides a kind of plant extracts composite feed additive, it is made up of various plants micro mist and plant extracts proportioning.
The invention provides a kind of plant extracts composite feed additive, it forms (each amounts of components is a weight portion) by following component
Fructus Crataegi micropowder 15-20
Purslane herb micro mist 15-25
Honegsukle flower P.E 10-25
Dandelion extract 15-20
Grape seed extract 10-25
Andrographis Paniculata 10-20
Echinacea Purpurea Herb P.E: 10-15
Astragalus Root P.E 8-15
In a preferred embodiment of the invention, consisting of of plant extracts composite feed additive of the present invention:
Fructus Crataegi micropowder 15
Purslane herb micro mist 20
Honegsukle flower P.E 10
Dandelion extract 15
Grape seed extract 10
Andrographis Paniculata 10
Echinacea Purpurea Herb P.E: 10
Astragalus Root P.E 10
In a preferred embodiment of the invention, consisting of of plant extracts composite feed additive of the present invention:
Fructus Crataegi micropowder 15
Purslane herb micro mist 20
Honegsukle flower P.E 15
Dandelion extract 15
Grape seed extract 15
Andrographis Paniculata 10
Echinacea Purpurea Herb P.E: 15
Astragalus Root P.E 10
Animal is fed and tests proof: plant extracts composite feed additive of the present invention can effectively improve newborn piglet daily gain, significantly reduces sucking pig diarrhoea.
Therefore, the invention provides plant extracts composite feed additive according to the invention improves newborn young animal intestines and stomach function, prevention or controls the purposes in the feed addictive of newborn young animal diarrhoea in preparation.
In a preferred embodiment of the invention, the young animal of said breast is newborn piglet.
On the other hand, the invention provides a kind of preparation method of plant extracts composite feed additive.This method comprises the following steps:
(1) preparation of Fructus Crataegi micropowder: with the hawthorn impurity elimination, pulverize, collect wherein micro mist through 80-100 mesh sieve sheet
(2) preparation of purslane micro mist: get the purslane herb, impurity elimination grinds, and collects the micro mist through 80-100 mesh sieve sheet
(3) preparation of Andrographis Paniculata: the Folium Andrographis impurity elimination, grind into powder; Adding volume ratio then is 1:8-10 95% alcohol immersion doubly 2 hours; Filter and collect filtrating, in filter residue, adding volume ratio once more is 1:3-5 95% alcohol immersion doubly 3 hours, collects filtrating.Merge twice filtrating and with activated carbon decolorizing 1 hour, cross and filter destainer, distillation obtains Andrographis Paniculata after reclaiming ethanol
(4) preparation of Honegsukle flower P.E: the honeysuckle impurity elimination, grind into powder, adding volume ratio then is 1:8-10 water doubly, and refluxing extraction 2 hours is filtered and collected filtrating.In filter residue, adding volume ratio once more is 1:5 water doubly, continues to reflux 2 hours; Filter and collect filtrating, merge filtrating twice, concentrate the back evaporate to dryness
(5) preparation of grape seed extract: the grape pip impurity elimination, grind into powder, adding volume ratio is 1:8-12 water doubly, and refluxing extraction 2 hours is filtered and collected filtrating.In filter residue, add volume ratio 1:5 water doubly once more, continue to reflux 2 hours.Filter and collect filtrating, discard the filter residue merging filtrate, filtrating concentrates the back evaporate to dryness
(6) preparation of dandelion extract: the dandelion impurity elimination, grind into powder, adding volume ratio is 1:10-15 water logging bubble doubly 2-4 hour, and refluxing extraction is 2 hours then, filters and collects filtrating.In filter residue, adding volume ratio once more is 1:5-10 water doubly, continues to reflux 2 hours.Filter and collect filtrating, discard the filter residue merging filtrate, concentrate the back evaporate to dryness
(7) preparation of described Echinacea Purpurea Herb P.E: Echinacea impurity elimination, chopping are handled, and adding volume ratio then is 1:8-12 60% ethanol doubly, and heating and refluxing extraction 2 hours is filtered and collected filtrating.In filter residue, adding volume ratio once more is 1:5-8 60% ethanol doubly, continues to reflux 2 hours.Filter and collect filtrating, discard the filter residue merging filtrate, collect gained filtrating and concentrate the back decompressing and extracting
(8) preparation of Astragalus Root P.E: take by weighing impurity elimination, chopping processing, adding volume ratio is 1:8-10 water logging bubble doubly 4 hours, refluxing extraction 2 hours; Filter and collect filtrating, in filter residue, adding volume ratio once more is 1:5 water refluxing extraction doubly 2 hours, filters and collects filtrating; Discard the filter residue merging filtrate, separate with the macroporous absorbent resin post then, use water elution; Collect eluent, concentrate the back evaporate to dryness
(9) micro mist and the extract that above-mentioned steps are obtained mix in proportion
Fructus Crataegi micropowder 15-20
Purslane herb micro mist 15-25
Honegsukle flower P.E 10-25
Dandelion extract 15-20
Grape seed extract 10-25
Andrographis Paniculata 10-20
Echinacea Purpurea Herb P.E: 10-15
Astragalus Root P.E 8-15
In a preferred embodiment of the invention, being mixed in proportion described in the step (9) wherein:
Fructus Crataegi micropowder 15
Purslane herb micro mist 20
Honegsukle flower P.E 10
Dandelion extract 15
Grape seed extract 10
Andrographis Paniculata 10
Echinacea Purpurea Herb P.E: 10
Astragalus Root P.E 10
In another preferred embodiment of the present invention, being mixed in proportion described in the step (9) wherein:
Fructus Crataegi micropowder 15
Purslane herb micro mist 20
Honegsukle flower P.E 15
Dandelion extract 15
Grape seed extract 10
Andrographis Paniculata 10
Echinacea Purpurea Herb P.E: 15
Astragalus Root P.E 10
Advantage of the present invention
Plant extracts composite feed additive of the present invention is selected pure natural plant for use; Processes such as broken through micro mist, as to extract, concentrate forms; Have that raw material sources are extensive, bioavailability is high, the characteristics of nontoxic, noresidue, avoided antibiotic to accumulate in animal body from the source.The present invention can significantly reduce the sucking pig diarrhoea that a variety of causes causes, improves newborn piglet daily gain, strengthens humoral immunity and the cellular immunity function of newborn piglet.
Below in conjunction with embodiment, specific embodiments of the invention is done and is further described.Following examples only are used to explain the present invention, but are not used for limiting scope of the present invention.
Embodiment
The preparation of embodiment 1 plant crushed material and plant extracts
The preparation of Fructus Crataegi micropowder: with the hawthorn impurity elimination, pulverize, collect wherein micro mist through 80 mesh sieve sheets.
The preparation of purslane micro mist: get the purslane herb, impurity elimination grinds, and collects the micro mist through 80 mesh sieve sheets.
The preparation of Andrographis Paniculata: the Folium Andrographis impurity elimination, grind into powder, add 95% alcohol immersion 2 hours of 8 times of volumes then, filter and collect filtrating, in filter residue, add 95% alcohol immersion 3 hours of 3 times of volumes once more, collect filtrating.Merge twice filtrating and with activated carbon decolorizing 1 hour, cross and filter destainer, distillation obtains Andrographis Paniculata after reclaiming ethanol.
The preparation of Honegsukle flower P.E: the honeysuckle impurity elimination, grind into powder, add the water of 8 times of volumes then, refluxing extraction 2 hours is filtered and is collected filtrating.The water that in filter residue, adds 5 times of volumes once more continues to reflux 2 hours; Filter and collect filtrating, merge filtrating twice, concentrate the back evaporate to dryness.
The preparation of grape seed extract: the grape pip impurity elimination, grind into powder, add the water of 8 times of volumes, refluxing extraction 2 hours is filtered and is collected filtrating.The water that in filter residue, adds 5 times of volumes once more continues to reflux 2 hours.Filter and collect filtrating, discard the filter residue merging filtrate, filtrating concentrates the back evaporate to dryness.
The preparation of dandelion extract: the dandelion impurity elimination, grind into powder, add the water logging bubble 2 hours of 10 times of volumes, refluxing extraction is 2 hours then, filters and collects filtrating.The water that in filter residue, adds 5 times of volumes once more continues to reflux 2 hours.Filter and collect filtrating, discard the filter residue merging filtrate, concentrate the back evaporate to dryness.
The preparation of Echinacea Purpurea Herb P.E: Echinacea impurity elimination, chopping are handled, and add 60% ethanol of 8 times of volumes then, and heating and refluxing extraction 2 hours is filtered and collected filtrating.60% ethanol that in filter residue, adds 5 times of volumes once more continues to reflux 2 hours.Filter and collect filtrating, discard the filter residue merging filtrate, collect gained filtrating and concentrate the back decompressing and extracting.
The preparation of Astragalus Root P.E: take by weighing impurity elimination, chopping processing, refluxing extraction 2 hours was steeped in the water logging that adds 8 times of volumes 4 hours; Filter to collect filtrating, in filter residue, add the water refluxing extraction 2 hours of 5 times of volumes once more, filter and collect filtrating; Discard the filter residue merging filtrate, separate with the macroporous absorbent resin post then, use water elution; Collect eluent, concentrate the back evaporate to dryness.
The preparation of embodiment 2 plant crushed materials and plant extracts
The preparation of Fructus Crataegi micropowder: with the hawthorn impurity elimination, pulverize, collect wherein micro mist through 100 mesh sieve sheets.
The preparation of purslane micro mist: get the purslane herb, impurity elimination grinds, and collects the micro mist through 100 mesh sieve sheets.
The preparation of Andrographis Paniculata: the Folium Andrographis impurity elimination, grind into powder, add 95% alcohol immersion 2 hours of 10 times of volumes then, filter and collect filtrating, in filter residue, add 95% alcohol immersion 3 hours of 5 times of volumes once more, collect filtrating.Merge twice filtrating and with activated carbon decolorizing 1 hour, cross and filter destainer, distillation obtains Andrographis Paniculata after reclaiming ethanol.
The preparation of Honegsukle flower P.E: the honeysuckle impurity elimination, grind into powder, add the water of 10 times of volumes then, refluxing extraction 2 hours is filtered and is collected filtrating.The water that in filter residue, adds 5 times of volumes once more continues to reflux 2 hours; Filter and collect filtrating, merge filtrating twice, concentrate the back evaporate to dryness.
The preparation of grape seed extract: the grape pip impurity elimination, grind into powder, add the water of 12 times of volumes, refluxing extraction 2 hours is filtered and is collected filtrating.The water that in filter residue, adds 5 times of volumes once more continues to reflux 2 hours.Filter and collect filtrating, discard the filter residue merging filtrate, filtrating concentrates the back evaporate to dryness.
The preparation of dandelion extract: the dandelion impurity elimination, grind into powder, add the water logging bubble 4 hours of 15 times of volumes, refluxing extraction is 2 hours then, filters and collects filtrating.The water that in filter residue, adds 10 times of volumes once more continues to reflux 2 hours.Filter and collect filtrating, discard the filter residue merging filtrate, concentrate the back evaporate to dryness.
The preparation of Echinacea Purpurea Herb P.E: Echinacea impurity elimination, chopping are handled, and add 60% ethanol of 12 times of volumes then, and heating and refluxing extraction 2 hours is filtered and collected filtrating.In filter residue, add 8 times of 60% ethanol of mentioning once more, continue to reflux 2 hours.Filter and collect filtrating, discard the filter residue merging filtrate, collect gained filtrating and concentrate the back decompressing and extracting.
The preparation of Astragalus Root P.E: take by weighing impurity elimination, chopping processing, refluxing extraction 2 hours was steeped in the water logging that adds 10 times of volumes 4 hours; Filter to collect filtrating, in filter residue, add the water refluxing extraction 2 hours of 5 times of volumes once more, filter and collect filtrating; Discard the filter residue merging filtrate, separate with the macroporous absorbent resin post then, use water elution; Collect eluent, concentrate the back evaporate to dryness.
The preparation of embodiment 3 plant extracts compound additives
The plant micro mist or the plant extracts of embodiment 1 or embodiment 2 preparations are pressed following weight portion proportioning:
Fructus Crataegi micropowder 15
Purslane herb micro mist 15
Honegsukle flower P.E 10
Dandelion extract 15
Grape seed extract 10
Andrographis Paniculata 10
Echinacea Purpurea Herb P.E: 10
Astragalus Root P.E 8
Above-mentioned each component mixing obtains plant extracts additive of the present invention.
The preparation of embodiment 4 plant extracts compound additives
The plant micro mist or the plant extracts of embodiment 1 or embodiment 2 preparations are pressed following weight portion proportioning:
Fructus Crataegi micropowder 20
Purslane herb micro mist 25
Honegsukle flower P.E 25
Dandelion extract 20
Grape seed extract 25
Andrographis Paniculata 20
Echinacea Purpurea Herb P.E: 15
Astragalus Root P.E 15
Above-mentioned each component mixing obtains plant extracts additive of the present invention.
The preparation of embodiment 5 plant extracts compound additives
The plant micro mist or the plant extracts of embodiment 1 or embodiment 2 preparations are pressed following weight portion proportioning:
Fructus Crataegi micropowder 15
Purslane herb micro mist 20
Honegsukle flower P.E 10
Dandelion extract 15
Grape seed extract 10
Andrographis Paniculata 10
Echinacea Purpurea Herb P.E: 10
Astragalus Root P.E 10
Above-mentioned each component mixing obtains plant extracts compound additive of the present invention.
The preparation of embodiment 6 plant extracts compound additives
The plant micro mist or the plant extracts of embodiment 1 or embodiment 2 preparations are pressed following weight portion proportioning:
Fructus Crataegi micropowder 15
Purslane herb micro mist 20
Honegsukle flower P.E 15
Dandelion extract 15
Grape seed extract 10
Andrographis Paniculata 10
Echinacea Purpurea Herb P.E: 15
Astragalus Root P.E 10
Above-mentioned each component mixing obtains plant extracts compound additive of the present invention.
The experiment of feeding of embodiment 7 animals
With reference to the swine rearing standard, preparation and the suitable basal diet of child care pig nutrient concentration, the prescription of basal diet and nutritional labeling are not seen table 1,2.
Basal diet per ton adds plant compound additive 300 grams of embodiment 3 preparations as the experimental group daily ration; Simultaneously, adding 10% colistin 300 gram at basal diet per ton restrains as the control group daily ration with 50% kitasamycin 100.
Select DLY tri-crossbreeding 8 nests, steamed bread of corn number and the size of 15 ages in days close, health, active, evenly individual.Be divided into 2 groups at random, experimental group 4 nests add up to 37, and control group 4 nests add up to 36, and newborn piglet growth, food consumption, diarrhoea etc. are observed and write down to experimental period to 42 ages in days, from 15 ages in days, sees table 3.
Claims (10)
1. plant extracts composite feed additive, it is made up of various plants micro mist and plant extracts proportioning.
2. the described plant extracts composite feed additive of claim 1, it consists of:
Fructus Crataegi micropowder 15-20
Purslane herb micro mist 15-25
Honegsukle flower P.E 10-25
Dandelion extract 15-20
Grape seed extract 10-25
Andrographis Paniculata 10-20
Echinacea Purpurea Herb P.E: 10-15
Astragalus Root P.E 8-15
Wherein the consumption of each component is a weight portion.
3. the described plant extract feed additive of claim 2, it consists of:
Fructus Crataegi micropowder 15
Purslane herb micro mist 20
Honegsukle flower P.E 10
Dandelion extract 15
Grape seed extract 10
Andrographis Paniculata 10
Echinacea Purpurea Herb P.E: 10
Astragalus Root P.E 10
Wherein the consumption of each component is a weight portion.
4. the described plant extract feed additive of claim 2, it consists of:
Fructus Crataegi micropowder 15
Purslane herb micro mist 20
Honegsukle flower P.E 15
Dandelion extract 15
Grape seed extract 10
Andrographis Paniculata 10
Echinacea Purpurea Herb P.E: 15
Astragalus Root P.E 10
Wherein the consumption of each component is a weight portion.
5. each said plant extract feed additive improves newborn young animal intestines and stomach function, prevention or controls the purposes in the feed addictive of newborn young animal diarrhoea in preparation among the claim 1-4.
6. the purposes of claim 5, the young animal of wherein said breast is newborn piglet. a kind of preparation method of plant extract feed additive.
7. this method comprises the following steps:
(1) preparation of Fructus Crataegi micropowder: with the hawthorn impurity elimination, pulverize, collect wherein micro mist through 80-100 mesh sieve sheet
(2) preparation of purslane micro mist: get the purslane herb, impurity elimination grinds, and collects the micro mist through 80-100 mesh sieve sheet
(3) preparation of Andrographis Paniculata: the Folium Andrographis impurity elimination, grind into powder; Adding volume ratio then is 1:8-10 times of 95% alcohol immersion 2 hours; Filter and collect filtrating, in filter residue, adding volume ratio once more is 1:3-5 times of 95% alcohol immersion 3 hours, collects filtrating
Merge twice filtrating and with activated carbon decolorizing 1 hour, cross and filter destainer, distillation obtains Andrographis Paniculata after reclaiming ethanol
(4) preparation of Honegsukle flower P.E: the honeysuckle impurity elimination, grind into powder, adding volume ratio then is 1:8-10 times of water, and refluxing extraction 2 hours is filtered and collected filtrating
In filter residue, adding volume ratio once more is 1:5 times of water, continues to reflux 2 hours; Filter and collect filtrating, merge filtrating twice, concentrate the back evaporate to dryness
(5) preparation of grape seed extract: the grape pip impurity elimination, grind into powder, adding volume ratio is 1:8-12 times of water, and refluxing extraction 2 hours is filtered and collected filtrating
In filter residue, adding volume ratio once more is 1:5 water, continues to reflux 2 hours
Filter and collect filtrating, discard the filter residue merging filtrate, filtrating concentrates the back evaporate to dryness
(6) preparation of dandelion extract: the dandelion impurity elimination, grind into powder, adding volume ratio is that 10-15 times of water gaging soaked 2-4 hour, and refluxing extraction is 2 hours then, filters and collects filtrating
In filter residue, adding volume ratio once more is 1:5-10 times of water, continues to reflux 2 hours
Filter and collect filtrating, discard the filter residue merging filtrate, concentrate the back evaporate to dryness
(7) preparation of described Echinacea Purpurea Herb P.E: Echinacea impurity elimination, chopping are handled, and adding volume ratio then is doubly 60% ethanol of 1:8-12, and heating and refluxing extraction 2 hours is filtered and collected filtrating
In filter residue, adding volume ratio once more is doubly 60% ethanol of 1:5-8, continues to reflux 2 hours
Filter and collect filtrating, discard the filter residue merging filtrate, collect gained filtrating and concentrate the back decompressing and extracting
(8) preparation of Astragalus Root P.E: Radix Astragali impurity elimination, chopping are handled, and adding volume ratio is that 1:8-10 times of water gaging soaked refluxing extraction 2 hours 4 hours; Filter and collect filtrating, in filter residue, adding volume ratio once more is 1:5 water refluxing extraction doubly 2 hours, filters and collects filtrating; Discard the filter residue merging filtrate; Separate with the macroporous absorbent resin post then, use water elution, collect eluent.
(9) micro mist and the extract that above-mentioned steps are obtained mix in proportion.
8. the preparation method of claim 7, wherein micro mist and the extract described in the step (9) is mixed in proportion:
Fructus Crataegi micropowder 15-20
Purslane herb micro mist 15-25
Honegsukle flower P.E 10-25
Dandelion extract 15-20
Grape seed extract 10-25
Andrographis Paniculata 10-20
Echinacea Purpurea Herb P.E: 10-15
Astragalus Root P.E 8-15
Wherein the consumption of each component is a weight portion.
9. the preparation method of claim 7, wherein micro mist and the extract described in the step (9) is mixed in proportion:
Fructus Crataegi micropowder 15
Purslane herb micro mist 20
Honegsukle flower P.E 10
Dandelion extract 15
Grape seed extract 10
Andrographis Paniculata 10
Echinacea Purpurea Herb P.E: 10
Astragalus Root P.E 10
Wherein the consumption of each component is a weight portion.
10. the preparation method of claim 7, wherein micro mist and the extract described in the step (9) is mixed in proportion:
Fructus Crataegi micropowder 15
Purslane herb micro mist 20
Honegsukle flower P.E 15
Dandelion extract 15
Grape seed extract 10
Andrographis Paniculata 10
Echinacea Purpurea Herb P.E: 15
Astragalus Root P.E 10
Wherein the consumption of each component is a weight portion.
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