CN1022165C - Preparation method of oral liquid for regulating pulse - Google Patents
Preparation method of oral liquid for regulating pulse Download PDFInfo
- Publication number
- CN1022165C CN1022165C CN 88105365 CN88105365A CN1022165C CN 1022165 C CN1022165 C CN 1022165C CN 88105365 CN88105365 CN 88105365 CN 88105365 A CN88105365 A CN 88105365A CN 1022165 C CN1022165 C CN 1022165C
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- Prior art keywords
- radix
- medicine
- liquid
- medicinal liquid
- juice
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- Expired - Lifetime
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- 239000007788 liquid Substances 0.000 title claims description 18
- 238000002360 preparation method Methods 0.000 title abstract description 3
- 230000001105 regulatory effect Effects 0.000 title 1
- 239000003814 drug Substances 0.000 claims abstract description 23
- 238000000034 method Methods 0.000 claims abstract description 6
- 108010052008 colla corii asini Proteins 0.000 claims description 11
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 10
- 241000208340 Araliaceae Species 0.000 claims description 8
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 8
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 8
- 235000008434 ginseng Nutrition 0.000 claims description 8
- 241000628997 Flos Species 0.000 claims description 7
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 241000222640 Polyporus Species 0.000 claims description 4
- 239000000796 flavoring agent Substances 0.000 claims description 4
- 235000019634 flavors Nutrition 0.000 claims description 4
- 235000019082 Osmanthus Nutrition 0.000 claims description 3
- 241000333181 Osmanthus Species 0.000 claims description 3
- 235000021551 crystal sugar Nutrition 0.000 claims description 3
- 239000003205 fragrance Substances 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 231100000252 nontoxic Toxicity 0.000 claims description 3
- 230000003000 nontoxic effect Effects 0.000 claims description 3
- 241000756943 Codonopsis Species 0.000 claims description 2
- 230000002421 anti-septic effect Effects 0.000 claims description 2
- 239000003963 antioxidant agent Substances 0.000 claims description 2
- 230000003078 antioxidant effect Effects 0.000 claims description 2
- 238000004140 cleaning Methods 0.000 claims description 2
- 239000011521 glass Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 238000012856 packing Methods 0.000 claims description 2
- 239000011435 rock Substances 0.000 claims description 2
- 238000007873 sieving Methods 0.000 claims description 2
- 230000001954 sterilising effect Effects 0.000 claims description 2
- 238000004659 sterilization and disinfection Methods 0.000 claims description 2
- 235000013547 stew Nutrition 0.000 claims description 2
- 235000000346 sugar Nutrition 0.000 claims description 2
- 229910052573 porcelain Inorganic materials 0.000 claims 1
- 201000010099 disease Diseases 0.000 abstract description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 6
- 210000004204 blood vessel Anatomy 0.000 abstract description 5
- 208000011580 syndromic disease Diseases 0.000 abstract description 3
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 244000248825 Peltandra virginica Species 0.000 abstract 1
- 235000001188 Peltandra virginica Nutrition 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 241000304195 Salvia miltiorrhiza Species 0.000 abstract 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002458 infectious effect Effects 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 6
- 230000000694 effects Effects 0.000 description 4
- 206010020772 Hypertension Diseases 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 3
- 206010014599 encephalitis Diseases 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 230000035939 shock Effects 0.000 description 3
- 208000004880 Polyuria Diseases 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 229940126678 chinese medicines Drugs 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 201000011475 meningoencephalitis Diseases 0.000 description 2
- 239000002547 new drug Substances 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- 201000002498 viral encephalitis Diseases 0.000 description 2
- 208000006400 Arbovirus Encephalitis Diseases 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 206010048962 Brain oedema Diseases 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 201000005488 Capillary Leak Syndrome Diseases 0.000 description 1
- 244000077995 Coix lacryma jobi Species 0.000 description 1
- 235000007354 Coix lacryma jobi Nutrition 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010052369 Encephalitis lethargica Diseases 0.000 description 1
- 206010014612 Encephalitis viral Diseases 0.000 description 1
- 206010061192 Haemorrhagic fever Diseases 0.000 description 1
- 239000009636 Huang Qi Substances 0.000 description 1
- 208000001953 Hypotension Diseases 0.000 description 1
- 206010034038 Parotitis Diseases 0.000 description 1
- 206010056430 Staphylococcal sepsis Diseases 0.000 description 1
- 208000031932 Systemic capillary leak syndrome Diseases 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000000703 anti-shock Effects 0.000 description 1
- 208000006752 brain edema Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
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- 230000002008 hemorrhagic effect Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 208000021822 hypotensive Diseases 0.000 description 1
- 230000001077 hypotensive effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
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- 238000011160 research Methods 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
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Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a blood vessel nutrient agent-formula of pulse-regulating oral liquor and its preparation process. The formula components of the medicine mainly comprise radix pseudostellariae, donkey-hide gelatin, tuckahoe, rhizoma alismatis, salvia miltiorrhiza and the like. The process is simple, the medicine source is wide, and one proof is provided from the collected ninety cases, so that the invention can effectively treat the diffuse capillary vessel leakage syndrome. Many diseases which clinically cause the syndromes are widely distributed in internal, external, gynecological, children, skin, eyes, infectious departments and the like. One medicine can cure many diseases, so the sale is wide and the economic benefit is high.
Description
What the present invention relates to is that a kind of vascular leakage of forming with Chinese medicines such as Colla Corii Asini of effectively preventing reaches vascular nutrition agent-integrated pulse liquor that complete sum is adjusted blood vessels, its prescription and technological process.
There is the intravenous injection of human zoopery proof can rise blood pressure, but do not do experiment with oral medication, want EV a large amount of stagnant water are changed in the blood vessel, that just must have sound blood vessel wall to produce normal the transfer dynamically, only in this way could solve the problem of diffuse capillary leak, just can reach excellent curative.
The objective of the invention is to problem at above-mentioned existence, propose a kind of new drug of forming with Chinese medicines such as Colla Corii Asini and and overlap the production technology of making this new drug, solve the unsolved thorny difficult problem in the world, promptly diffuse capillary leak reaches effective therapeutic effect.
Technical solution of the present invention:
One, prescription,
Form by Colla Corii Asini, Radix Ginseng, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Cortex Moutan, Rhizoma Chuanxiong, Flos Imperatae, Poria, Rhizoma Alismatis, Polyporus, crystal sugar, osmanthus flower fragrance etc.Their composition scope is: Colla Corii Asini 10-45, Radix Ginseng 10-20, Radix Salviae Miltiorrhizae 10-25, Radix Paeoniae Rubra 5-15, Cortex Moutan 6-12, Rhizoma Chuanxiong 10-20, Flos Imperatae 6-15, Poria 10-30, Rhizoma Alismatis 10-30, Polyporus 10-30, crystal sugar and osmanthus flower fragrance a little.(above-mentioned unit is gram)
Through evidence, Radix Ginseng can use Qi-tonifying drugs such as the Radix Astragali, Radix Codonopsis, Radix Pseudostellariae, Rhizoma Polygonati, Radix Glycyrrhizae for it; Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Rhizoma Chuanxiong can be used Radix Angelicae Sinensis, Flos Carthami, Herba Lycopi, milettia reticulata Radix Curcumae Radix Et Rhizoma Rhei, Herba Leonuri, cattle
Deng blood circulation promoting dispels the silt medicine for it; Rhizoma Chuanxiong is warm in nature, and the person that has the Rhizoma Chuanxiong can be without Radix Aconiti Lateralis Preparata isothermal medicine, has to add the person that uses the Radix Aconiti Lateralis Preparata, and Rhizoma Chuanxiong dosage is less than normal; Poria can be with drugs strengthening spleens such as the Rhizoma Atractylodis Macrocephalaes for it (fry seed of Job's tears also can for it); Poria has promoting diuresis to eliminate damp pathogen effect and side to go up Polyporus, Rhizoma Alismatis again can substitute it with other promoting diuresis to eliminate damp pathogen medicine such as Semen Plantaginis (grass), Herba Polygoni Avicularis, Medulla Junci, Exocarpium Benincasae etc.; Flos Imperatae can with fry BOHUANG, fry Radix Rubiae equivalent it.
Keep principal agent if the top is removed the flavour of a drug of various effects, and it is still effective to strengthen the dosage of certain principal agent, but effect is inferior slightly, if consist of: Radix Pseudostellariae, Colla Corii Asini, Poria, Rhizoma Alismatis, Radix Salviae Miltiorrhizae are also effective.
The Radix Angelicae Sinensis Colla Corii Asini has relieving constipation, the effect of invigorating blood circulation, and Fang Zhongruo adds the Radix Et Rhizoma Rhei, and the former amount of person can be less than normal.
Two, the technological process of production of integrated pulse liquor:
1. the Radix Ginseng list decocts or stewes in addition, extracting juice, and three times repeatedly, medicinal residues are needed with juice extractor medicine juice to be drained only at every turn, three times medicine juice mixing is poured on together, filters;
2. Colla Corii Asini water proof molten, medicinal china bowl or other non-metallic vessel dress;
3. pour out medicinal liquid after other each flavor mixing decocts 30 minutes with marmite, adding the water secondary again repeats, pour out medicinal liquid after 30 minutes again, medicinal residues must drain only with juice extractor, the secondary medicinal liquid is still used the fine mesh sieving after mixing, about medicinal liquid simmer down to 60ml, liquid is poured in the Colla Corii Asini of molten, fully stirred well even, add ginseng liquid and a small amount of antiseptic and antioxidant again, reconcentration becomes 90ml left and right sides medicinal liquid after stirring all, and Flos Osmanthi Fragrantis (processed with sugar) essence material on the rocks again reaches total liquid measure 100ml, injection is handled in the nontoxic ampere bottle (glass) of one of the dried 20ml that baked in back with cleaning solution, seal, autoclave sterilization again, every 100ml divide five to be box packing.
The present invention succeeded in developing for 8 years, example surplus the collection case 90, surplus 90 in the example, mainly is that (this institute is the provincial R﹠D institution in Jiangsu Province, the research point of economizing prevention and treatment in Chinese and western hemorrhagic fever cooperative groups) collects in the People's Hospital, Gaochun County, Jiangsu Province at this, account for 70 surplus example.The disease kind of example comprises surplus in the of 90: the epizootic hemorrhagic hot body example surplus in the of 70 of setting a time limit, sudden and violent brain body gram type two examples, sudden and violent brain mixed type (having shock to add meningoencephalitis) two examples, sudden and violent brain meningoencephalitis type one example, epidemic encephalitis type B (heavy type) five examples, the concurrent sense beam of staphylococcus aureus septicemia shock (rescue) two examples, viral encephalitis three examples, parotitis and encephalitis one example.Medication all about one day to two days, is no more than three days, and most of medications are once promptly effectively stopped using to three times, and dosage will be grasped with the state of an illness flexibly by different sick profits, all your disease of the no any back of treatment.
Clinical practice is verified, the invention solves the capillary leak syndrome that specific medicament never can be controlled, yet the disease that produces this class syndrome clinically is a lot, be widely distributed in inside and outside, woman, youngster, skin, eye, contagious department etc., one medicine energy Zhiduo County disease, make to sell and set up in a wide range, economic benefit is obvious; Fully and consumingly show motherland's theory of medicine characteristic, can outstanding illustrate the prescription of the theory of Chinese medical science characteristic of globality Selfstabilizing, promptly hypertension person's cerebral edema patient obeys the back blood pressure drops, but Antishock function is arranged, hypotensive shock clothes back increased blood pressure causes normally, but can not cause hypertension; Flavour of a drug are more gentle, and nontoxic no strong medicine all has the science analysis data to can be used as index to contraindication and points for attention, are easy to be grasped by the doctor trained in Western medicine personage and be willing to accept, dialectical execute control also uncomplicated; Prescription is simple, technological process is also uncomplicated; Medical herbs medicine source is not difficult.
Claims (1)
1, a kind of technological process of making the production integrated pulse liquor is characterized in that: (1) prescription composition scope is: Colla Corii Asini 10-45, Radix Ginseng (or Radix Codonopsis) 10-20, Radix Salviae Miltiorrhizae 10-25, Radix Paeoniae Rubra 5-15, Cortex Moutan 6-12, Rhizoma Chuanxiong 10-20, Flos Imperatae 6-15, Poria 10-30, Rhizoma Alismatis 10-30, Polyporus 10-30, crystal sugar and osmanthus flower fragrance a small amount of (unit is gram); (2) the Radix Ginseng list boils or stewes in addition, extracting juice, and three times repeatedly, medicinal residues are needed with juice extractor medicine juice to be drained only at every turn, three times medicine juice mixing is poured on together, filters; (3) Colla Corii Asini, water proof molten, medicine and porcelain or other non-metallic vessel dress; (4) other each flavor mixing decocts (using marmite) and poured out medicinal liquid in 30 minutes, adding the water secondary again repeats, pour out medicinal liquid after 30 minutes again, medicinal residues must drain only with juice extractor, the secondary medicinal liquid is still used the fine mesh sieving after mixing, about medicinal liquid simmer down to 60ml, liquid is poured in the Colla Corii Asini of molten, fully stirred well even, add ginseng liquid and a small amount of antiseptic again, reconcentration became 90ml left and right sides medicinal liquid after antioxidant stirred, and Flos Osmanthi Fragrantis (processed with sugar) essence material on the rocks again reaches total liquid measure 100ml, flowing into cleaning solution handles in the nontoxic ampere bottle (glass) that afterwards the dried 20ml-that baked props up, seal, autoclave sterilization again, every 10ml divide five to be box packing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 88105365 CN1022165C (en) | 1988-02-06 | 1988-02-06 | Preparation method of oral liquid for regulating pulse |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 88105365 CN1022165C (en) | 1988-02-06 | 1988-02-06 | Preparation method of oral liquid for regulating pulse |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1034672A CN1034672A (en) | 1989-08-16 |
| CN1022165C true CN1022165C (en) | 1993-09-22 |
Family
ID=4833566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 88105365 Expired - Lifetime CN1022165C (en) | 1988-02-06 | 1988-02-06 | Preparation method of oral liquid for regulating pulse |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1022165C (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1686503B (en) * | 2005-04-22 | 2010-11-10 | 复旦大学 | External use medicinal preparation for treating pelvic infection |
| CN102727677B (en) * | 2012-07-17 | 2014-02-19 | 程孝慈 | Novel compound donkey-hide glue extract powder formula, preparation and application of novel compound donkey-hide glue extract powder formula |
| WO2017010673A2 (en) * | 2015-07-16 | 2017-01-19 | 재단법인 지능형 바이오 시스템 설계 및 합성 연구단 | Composition for preventing or treating vascular leakage syndrome |
| CN108114151A (en) * | 2018-03-05 | 2018-06-05 | 汤红日 | A kind of Chinese medicine |
-
1988
- 1988-02-06 CN CN 88105365 patent/CN1022165C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1034672A (en) | 1989-08-16 |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C15 | Extension of patent right duration from 15 to 20 years for appl. with date before 31.12.1992 and still valid on 11.12.2001 (patent law change 1993) | ||
| OR01 | Other related matters | ||
| AD01 | Patent right deemed abandoned | ||
| C20 | Patent right or utility model deemed to be abandoned or is abandoned | ||
| CI01 | Publication of corrected invention patent application |
Correct: Revoked False: The patent right shall be deemed as abandonment of the notice Number: 42 Page: 886 Volume: 21 |
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| ERR | Gazette correction |
Free format text: CORRECT FROM: DEEMED TO ABANDON PATENT RIGHT ANNOUNCEMENT TO: REVOCATION |
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| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |