CN101454040A - Respiratory device measurement system - Google Patents
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- CN101454040A CN101454040A CNA2006800221205A CN200680022120A CN101454040A CN 101454040 A CN101454040 A CN 101454040A CN A2006800221205 A CNA2006800221205 A CN A2006800221205A CN 200680022120 A CN200680022120 A CN 200680022120A CN 101454040 A CN101454040 A CN 101454040A
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- 230000000241 respiratory effect Effects 0.000 title description 5
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- 230000005540 biological transmission Effects 0.000 claims description 31
- 238000005276 aerator Methods 0.000 claims description 22
- 238000000034 method Methods 0.000 claims description 21
- 230000009467 reduction Effects 0.000 claims description 10
- 230000008569 process Effects 0.000 claims description 4
- 230000001960 triggered effect Effects 0.000 claims 1
- 239000007789 gas Substances 0.000 description 140
- 230000029058 respiratory gaseous exchange Effects 0.000 description 11
- 238000012544 monitoring process Methods 0.000 description 9
- 230000006870 function Effects 0.000 description 5
- 230000008859 change Effects 0.000 description 3
- 230000001186 cumulative effect Effects 0.000 description 3
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- 238000012545 processing Methods 0.000 description 3
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
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- GWUAFYNDGVNXRS-UHFFFAOYSA-N helium;molecular oxygen Chemical compound [He].O=O GWUAFYNDGVNXRS-UHFFFAOYSA-N 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
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Abstract
A gas delivery system (12) comprising a pressure generator (14), a pressure sensor (21), a control valve (20), and a processor (32). The pressure generator (14) pressurizes breathable gas (22) for delivery to a patient. Th e pressure sensor (21) measures a pressure difference between the pressurized breathable gas (22) and atmospheric pressure. The control valve (20) is disposed downstream from the pressure generator (14) and is constructed and arranged to control a flow rate of the pressurized breathable gas (22). The processor (32) controls the control valve (20) to bring the flow rate of the pressurized breathable gas (22) to substantially zero while the pressure generator (14) is operating and, when the flow rate is substantially zero, determines at least one of atmospheric pressure, an atmospheric air density, or a density correction factor based at least in part on the pressure difference between the pressurized breathable gas (22) and the atmospheric pressure.
Description
Priority
The application enjoys the priority of the U. S. application of submitting on June 21st, 2,005 60/692,506 according to 35U.S.C. § 119 (e) request, and its full content is combined with reference at this.
Technical field
The present invention relates to breathing equipment.
Background technology
But known positive airway pressure (PAP) device from the pressurization respiratory air flow to the patient that carry.Usually, this PAP device comprises the pick off to pressure generator, one or more monitoring breathable gas and/or the various parameters of ambient atmosphere of breathable gas pressurization.The PAP device usually adopt the information that receives from pick off with controlled pressure generator following of feedback under desired pressure and/or flow velocity, to provide breathable gas to the patient.The PAP device also can be monitored the total amount to gas that the patient provides.
Determine to carry to the patient pressure, flow velocity and/or the cumulative volume of breathable gas for improving precision ground, some PAP devices comprise that various mechanism for example monitor atmospheric barometric pressure sensor to improve certainty of measurement.Although these pick offs can improve the precision of pressure, flow velocity and/or the cumulative volume of determining breathable gas, it has increased the totle drilling cost of this device.
Summary of the invention
The present invention relates to a kind of gas transmission system, comprise pressure generator, pressure transducer, control valve and processor.Pressure generator pressurizes to transmit to the patient to breathable gas.Pressure transducer is measured the breathable gas of pressurization and the pressure reduction between the atmospheric pressure.Control valve is arranged on the downstream of pressure generator and is configured and is set to control the flow velocity of pressurized breathable gas.Processor control control valve so that during the pressure generator operation flow velocity of pressurized breathable gas be substantially zero, and determine in atmospheric pressure, atmospheric density or the density correction factor at least one based on the pressure reduction between pressurized breathable gas and the atmospheric pressure when flow velocity is substantially zero up to small part.
The invention still further relates to a kind of gas transmission system, comprise pressure generator, pressure transducer, flow sensor and processor.Pressure generator pressurizes to transmit to the patient to breathable gas.Pressure transducer is measured the breathable gas of pressurization and the pressure reduction between the atmospheric pressure.Flow sensor measures is by the standard flow rate of pressurized breathable gas that pressure generator is exported.Processor to small part is determined in atmospheric pressure, atmospheric density or the density correction factor at least one based on the standard flow rate of pressure reduction and measurement.
The invention still further relates to the method for monitoring to the pressurized breathable gas of patient's transmission.This method comprises with the pressure generator pressurized breathable gas, determines to be applied to the pressure of breathable gas and to be determined in atmospheric pressure, atmospheric density or the density correction factor at least one based on the pressure that is applied to breathable gas by pressure generator to small part by pressure generator.
When considering below with reference to the description of accompanying drawing and accessory claim, these and other target of the present invention, character and feature, and the function of operation method and associated structural elements and part combination and manufacturing cost will be more clear, description below all and accessory claim form the part of this description, and wherein identical reference marker is represented the appropriate section in each accompanying drawing.But, can be expressly understood that accompanying drawing only is explanation and purpose of description and should not be construed as restriction definition of the present invention.As used in the specification and in the claims, " one " of singulative comprises plural indicant, unless clearly expression otherwise of context.
Description of drawings
Fig. 1 is the sketch map according to the patient treatment system of the embodiment of the invention;
Fig. 2 is the exemplary description according to the pressure generator of the embodiment of the invention;
Fig. 3 has described another configuration according to the patient treatment system of the embodiment of the invention; And
Fig. 4 is the exemplary description according to another configuration of patient treatment system of the embodiment of the invention.
The specific embodiment
Fig. 1 schematically describes exemplary first embodiment of patient treatment system 10 in accordance with the principles of the present invention.Patient treatment system 10 generally includes gas transmission system 12.Gas transmission system 12 be controlled to the patient breathable gas flow and comprise the pressure generator 14 that receives source of the gas 16 breathable gas of supplying.Among the embodiment, source of the gas 16 is atmosphere simply.Pressure generator 14 improves the gas pressure that source of the gas 16 is supplied to patient airway.
In one embodiment of the invention, Fig. 2 describes in more detail below with reference to, and pressure generator 14 comprises aerator.Aerator produces constant compression force or flow velocitys with constant speed drive to export 18 at it alternatively in pressure Supporting Therapy process.The present invention considers that also respiratory gas source 16 can be any respiratory gas source, air or oxygen mixture helium-oxygen gas mixture for example for example, the perhaps mixture of breathing gas and gas form medicine nitric oxide for example.
In described embodiment, gas transmission system 12 comprises control valve 20.The pressure rising gas flow that pressure generator 14 sends is transported to the control valve 20 in pressure generator 14 downstreams.Control valve 20 or leave the final pressure or the flow velocity of the gas 22 of gas transmission system 12 individually or with pressure generator 14 combination control.The example of control valve 20 can comprise sleeve pipe or cone valve, and its method as control patient catheter pressure is discharged gas from patient's conduit.As another example, people's such as Hete United States Patent (USP) 5,694,923 have instructed a kind of being suitable for as gas being drained into atmosphere and the restriction pressure generator 14 bipyramid valve system to the control valve 20 of patient's gas flow rate, and its whole content is combined in this as a reference.
Among the embodiment, the aerator of pressure generator 14 for only under a speed, moving.Among such embodiment, control valve 20 is controlled the final pressure and the flow velocity of the breathing gas 22 that is delivered to the patient separately.But the speed of service that the present invention also considers to jointly control valve 20 controlled pressure generators 14 aerators is delivered to the final pressure and the flow velocity of patient's breathing gas with control.For example, can set up pressure or the flow velocity (macro-control) that approaches desired pressure or flow velocity by the suitable speed of service of setting up aerator.Then can by 20 pairs of pressure of control valve or flow velocity carry out fine adjusting (micromanagement) thus both move the final pressure with the breathing gas of determining to be delivered to the patient together.
Can increase by being arranged on the pressure that pressure transducer 21 gaging pressure generators 14 between pressure generator 14 and the control valve 20 are applied to breathable gas.More especially, among the embodiment, pressure transducer 21 is arranged near the inlet or inlet of the control valve 20 of pressure generator 14 reception breathable gas.Pressure transducer 21 can be a differential pressure pickup of measuring control valve 20 inlets or near the pressure reduction of inlet.That is, pressure transducer 21 is measured control valve 20 inlets or the poor of near pressure of breathable gas delivered and atmospheric pressure that enter the mouth.The calibration difference pressure sensor is a zero pressure with the pressure measxurement around inciting somebody to action.Therefore, the pressure that measurement was substantially zero when differential pressure pick-up 21 was not worked when pressure generator 14, and the pressure of measuring to represent with the deviation of this null value pressure (atmospheric pressure) changes.
In the described embodiment of Fig. 1, gas transmission system 12 also comprises the flow sensor 24 that is used to measure the pressurized breathable gas standard flow rate.That is, calibration flow speed sensors 24 is in standard temperature (273K) and normal pressure (1 atmospheric pressure) with the supposition pressurized breathable gas, and therefore provides so-called " standard flow rate ".Because flow sensor 24 is measured " standard flow rate ", so because the temperature and pressure of breathable gas may this measured value can change a little along with volume flow rate along with therefore standard temperature and pressure (STP) change.Flow sensor 24 can comprise the equipment that is suitable for the measurement standard flow velocity, for example hot-wire anemometer, pulmonary function instrument, respiration rate instrument, variable openings pick off or other normal flow speed sensors.In described embodiment, flow sensor 24 is arranged on from patient interface assembly position far away.But the present invention considers flow sensor 24 is arranged on any position and is arranged on the patient interface assembly 28 along patient's conduit 26.For example, people's such as Starr United States Patent (USP) 6,017,315 has been instructed a kind of quantitative flow velocity element that is positioned at patient interface 28, and its full content combined reference is at this.
Carry gas flow from gas transmission system 12 to the patient through patient's conduit 26, this conduit is generally to patient interface assembly 28 and carries the single flexible conduit of gas flow.Patient interface assembly 28 is any intrusion or the non-intruding utensil that is suitable for to patient airway supply breathing gas, for example nose cup, nose/mask, whole face shield, nasal cannula, endotracheal tube or breathing catheter.Patient interface assembly 28 can comprise the head cap that utensil is installed in patient's head.In described embodiment, patient interface assembly 28 and/or patient's conduit 26 comprise the suitable outlet 30 that is used for from these parts atmosphere discharge towards periphery gas.Outlet 30 is preferably the passive outlet of continuous opening form, and it applies flow restriction to allow the gas pressure in the control patient interface assembly 28 to discharging gas.But, will be understood that outlet 30 can be to carry out the active outlet that difference is configured to control the velocity of discharge.For example at the United States Patent (USP) 5,685,296 and 5,937 of all authorizing people such as Zdrojkowski, instructed the example of suitable outlet in 885.
As shown in Figure 1, gas transmission system 12 comprises the processor module 32 of control gas transmission system 12 various ruuning situations.For example, provide the output of flow sensor 24 and pressure transducer 21, then to determine the standard flow rate and the differential pressure of delivery value patient's breathable gas if desired to processor module 32.
The control interface 34 that is included in the gas transmission system 12 provides data and order to processor module 32.Provide the equipment of information and/or order through rigid line or wireless connections to processor module 32 although control interface 34 can comprise any be fit to, the example of controlling interface 34 comprises keypad, keyboard, touch pads, mouse, mike, switch, button, dial or any other permission user equipment to patient treatment system 10 input informations.
The present invention considers that also patient's conduit 26 can be two brasnch conducts, and this point is common in conventional ventilation installation.Breathing gas is transmitted to the patient in first branch for example patient's conduit 26, and just it does not have outlet.On the contrary, second branch is from patient's Atmospheric Transportation discharge towards periphery gas, usually, the active outlet in controller (for example processor module 32) control second branch down for the patient provide the end-tidal of aspiration level rectify pressure (Positive end expiratory pressure, PEEP).In addition, gas delivery system 12 and relevant parts can comprise that other filtration, measurement, monitoring and analysis stream are to the patient or from the conventional equipment and the parts of patient's effluent air flow velocity, for example humidifier, heater, biofilter, humidity sensor and gas sensor (for example capnometer (capnometer)).
The actuating of processor module 32 control control valves 20, thus control is delivered to patient's breathing gas pressure.Processor module 32 is suitable for being applied to according to various air vent modes with calculating one or more algorithms programmings of patient's pressure.In more advanced embodiment of the present invention, processor module 32 selectively comprises the memorizer 36 relevant with gas transmission system 12, and it carries out any one needed program of multiple air vent mode according to nurse who uses control interface 34 or the selected air vent mode storage of patient.Memorizer 36 can also be stored about the data of patient treatment system 10 operations, input command, alert threshold and any other and move relevant information, for example measured value of patient's flow velocity, volume, pressure, equipment purposes, operating temperature and electromotor velocity with patient treatment system.
Fig. 2 is the exemplary description according to the pressure generator 14 of the embodiment of the invention.Pressure generator 14 comprises aerator 38, and it receives can absorb gas and improve from source of the gas 16 (not shown Fig. 2) and greater than ambient pressure is being the pressure that is delivered to patient's absorbed gas under the atmospheric pressure.By patient's conduit 26 the breathable gas stream that pressurizes is delivered to the patient then.
Go out as shown in Figure 2, aerator 38 comprises the impeller 40 that is positioned at cover 42.Be coupled to motor 44 rotary blades 40 of driving shaft 46.Breathable gas is delivered to the center of impeller 40 through blower inlet 50.The rotation of impeller 40 is exerted pressure to breathable gas, thereby to gas pressurized and at blower export 52 this gas is released aerator 38.Operation by processor module 32 control motor 44.In one embodiment of the invention, processor module 32 speed that can adjust motor 44 is treated desired pressure by pressure generator 14 outputs with setting.For this reason, be provided at conventional control device that control comprises in the interface 34, for example select the output pressure of expectation and therefore select the speed of service of motor 44 to provide input to processor module 32.By measuring the speed of service of motor 44 with the current meter 48 of processor module 32 cooperations.People's such as Truitt United States Patent (USP) 6,622,724 has been described the aerator and the impeller that can be used as aerator 38 and impeller 40 in one embodiment of the invention especially, and its full content combined reference is at this.
In other embodiments of the invention, pressure generator 14 can be not depart from piston, pump or the bellows of listed principle here.
Get back to Fig. 1, at gas transmission system 12 duration of works, processor module 32 determines to be delivered to patient's breathable gas stream not by pressure transducer 21 and the flow sensor 24 direct various parameters of measuring.For example, processor 32 can be determined volume flow rate or other parameter of atmospheric pressure (being barometer pressure), atmospheric density, pressurized breathable gas.Wherein, definite volume that can make processor module 32 monitoring be delivered to the breathable gas of patient interface assembly 28 of these parameters.
The breathable gas volume that is delivered to patient interface assembly 28 depends on the volume flow rate of pressurized breathable gas.But the flow velocity that flow sensor 24 is measured is a standard flow rate, if the pressure and temperature of breathable gas is in the status of criterion (for example 273K and 1 atmospheric pressure) then this standard flow rate will equal volume flow rate (the actual volume flow velocity of gas).Relation between volume flow rate and the standard flow rate is expressed as follows:
1. equation (1) Q
Vol=Q
Std* C;
Here Q
VolThe expression volume flow rate, Q
StdThe expression standard flow rate, and C represents density correction factor.Therefore, can be based on the standard flow rate of flow sensor 24 measurements and by determining the definite or approximate volumes flow velocity of density correction factor.For describing purpose, " density correction factor " is the scale factor that multiply by the volume flow rate of determining gas with the standard flow rate of air-flow mutually.Density correction factor is the function of ambient conditions in gas transmission system 12 and gas transmission system, for example ambient pressure, environment temperature and/or surrounding air density.For example can determine density correction factor according to following formula:
2. equation (2)
Adopt the ideal gas rule it can be rewritten as:
3. equation (3)
T wherein
mThe absolute temperature that expression is measured, T
StdThe expression standard temperature, P
StdThe expression normal pressure, P
mThe absolute pressure that expression is measured, ρ
StdExpression standard air density, and ρ
mThe atmospheric density that expression is measured.
For determining density correction factor according to equation (2) or one of them represented relation of (3), processor module 32 at first calculates to be measured absolute pressure (equation 2) or measures atmospheric density (equation 3).By carrying out several hypothesis, comprising: suppose the adiabatic process that is pressurised into of breathable gas; And hypothesis applies along impeller 44, and distinguishing gas pressure can be expressed as to the increase of breathable gas applied pressure by aerator 38 only for distinguishing the function of distance between volume and impeller 44 rotating shafts (being driving shaft 46) on any volume:
4. equation (4)
Wherein Δ P represents to increase P by 38 applied pressures of aerator
InletThe expression breathable gas is at the pressure of blower inlet 50, and ω represents the angular frequency of impeller 40, and r represents the radius of impeller 40, and R represents the gas constant of breathable gas, and T represents the temperature of breathable gas.
For determining atmospheric pressure by using equation (4), control valve 20 is closed when aerator 38 operations, effectively the flow velocity of breathable gas (standard and volume) is reduced to simultaneously zero (perhaps being substantially zero), this point causes the pressure (P of breathable gas at blower inlet 50
Inlet) equal (perhaps being substantially equal to) atmospheric pressure.This is because employed source of the gas 16 is atmosphere simply.Because pressure transducer 21 is arranged on the upstream (perhaps front) of control valve 20 and measures atmospheric pressure (equaling the pressure of blower inlet 50 now) and by aerator 38 pressurization but be closed absolute pressure poor of the breathable gas that control valve 20 stops, so pressure transducer 21 measured pressure reduction are substantially equal to be applied to by aerator 38 pressure (Δ P) of breathable gas.Based on this relation, can produce following formula to atmospheric pressure solves equation (4):
5. equation (5)
P wherein
AtmThe expression atmospheric pressure, P
DiffThe differential pressure that expression pressure transducer 21 is measured.Among the embodiment,, for example can directly measure the temperature of breathable gas by thermometer or gas temperature sensor although will increase the cost of equipment.Therefore, in another embodiment, can estimate temperature based on common service condition.Among the embodiment, suppose that the temperature of breathable gas is approximately 315 degree Kelvins.Among this embodiment, the pick off of temperature when flow sensor 24 can comprise compensated measurement gas-pressurized standard flow rate to a certain extent.For example, flow sensor 24 can comprise hot wire anemometer, and it has and comprises by constant current heating or maintain the core of hot line of the exposure of steady temperature.Among this embodiment, can be the function of walking heat by the pressurized breathable gas convective zone with the flow-speed measurement of pressurized breathable gas.As will be appreciated, because such anemometer will rely on the measurement (it will be influenced by the convection current of pick off environment temperature and pressurized breathable gas) of gas temperature, settle the standard flow velocity with the temperature around the part compensation sensor from this measurement.
Because atmospheric pressure (for example all night) during the patient uses patient treatment system 10 usually keeps relative stability usually, so only measure a subatmospheric when starting in one embodiment and suppose that it is constant, start when treating task at gas transmission system 12 promptly that control valve 32 is closed after aerator 38 is increased to the speed of service, determine atmospheric pressure separately so that processor module 32 begins to make in the treatment task.Think that during whole task atmospheric pressure is constant.Among another embodiment, closed control valve 20 is to start the calculating once more of ambient pressure during the treatment task.
Among other embodiment, can under the situation of closed control valve 20 not, determine atmospheric pressure.For example, in single branch system, for example in the patient treatment system 10, the breathable gas that the patient is carried gas transmission system 10 flows incoming call patient conduit 26.When the gas that leaves patient airway was compelled to get back to patient's conduit 26 to gas transmission system 12 to pressurized breathable gas stream, the instantaneous at least flow velocity of gas-pressurized that makes of this incoming call reduced to zero basically.Because the patient exhales or other phenomenon and do not produce identical with closing of control valve 20 basically condition through the air-flow of gas transmission system 12.This makes processor module 32 application equations (5) determine current atmospheric pressure from the measurement of pressure transducer 21, current meter 48 and temperature sensor (if perhaps patient treatment system 10 does not comprise temperature sensor then supposes a temperature).Among this embodiment, zero (or being substantially zero) instantaneous velocity measurement of flow sensor 24 can be used as triggering processor module 32 and recomputates current atmospheric predetermined trigger incident.
In case determine atmospheric pressure, then can add the differential pressure that detects by pressure transducer 21 (P for example by the atmospheric pressure that the front is determined
m=P
Atm+ P
Diff) and draw the absolute pressure of breathable gas.Adopt the measured value of absolute pressure, pass through the absolute pressure of breathable gas and temperature substitution equation (2) the monitoring density correction factor of breathable gas by processor module 32 then.Measure from the calculating of density correction factor and the standard flow rate of flow sensor 24, processor module 32 is according to the volume flow rate of equation (1) monitoring breathable gas.The volume flow rate of monitoring breathable gas makes processing module determine the breathable gas cumulative volume of being carried by gas transmission system 12, and based on the special parameter of breathable gas and the operation of ambient conditions adjustment pressure generator 14 and/or control valve 20.For example, processor module 32 can be based on the speed of determining to reduce motor 44 to raising atmospheric pressure (perhaps improving atmospheric density).Wherein, the speed that reduces motor 44 reduces the noise that gas transmission system 12 produced and reduces gas transmission system 12 employed power, and reduces the wearing and tearing of aerator 38 various parts (for example impeller 40, motor 44 and driving shaft 46) and tear.
Among the embodiment, processor module 32 is monitored the density of pressurized breathable gas according to following ideal gas law:
6. equation (6)
Among this embodiment, processing module 32 can be by with the calculating substitution equation (3) of this gas-pressurized density rather than adopt above-mentioned equation (2) monitoring density correction factor.
Will be understood that, the configuration of patient treatment system 10 shown in Figure 1 is not for the restriction purpose, and scope of the present invention comprises that any other makes processor module 32 monitor the configuration of directly not measuring this parameter to patient's gas-pressurized volume flow rate and/or atmospheric density and/or atmospheric pressure.For example, Fig. 3 has described the configuration of patient treatment system 10 according to an embodiment of the invention, and wherein gas transmission system 12 does not comprise control valve 20.In Fig. 3, identical part be endowed with Fig. 1 and 2 in identical Reference numeral.
In the configuration of the described patient treatment system 10 of Fig. 3, gas transmission system 12 only is sent to the pressure of patient's breathable gas based on the output control of pressure generator 14.That is, processor module 32 is controlled to patient's breathing gas pressure by the rotary speed of controlled pressure generator 14 only, and wherein pressure generator is aerator 38 once more.According to this embodiment, processor module 32 can be measured with feedback system controlled pressure generator 14 (with reference to figure 2) based on the one or many of pressure transducer 21 and/or 48 pairs of pressure of breathable gas delivered of current meter.
Because the configuration of gas transmission system 12 illustrated in fig. 3 does not comprise control valve 20, so the flow velocity of pressurized breathable gas can not be by processor module 32 vanishing controllably when pressure generator 14 operations.But, when the instantaneous velocity of pressurized breathable gas reaches zero, for example when reaching zero owing to patient's exhalation flow rate is instantaneous, perhaps by making other mechanism or the phenomenon of the vanishing of breathable gas flow velocity, processor module 32 still can be determined atmospheric pressure according to equation (5).Based on once determining (or repeatedly determining) to atmospheric, processing module can be monitored the density of pressurized breathable gas, the volume flow rate of breathable gas or other parameter of breathable gas as mentioned above.
According to an aspect of the present invention, can in feedback cycle, use measurement atmospheric pressure, atmospheric density and/or density correction factor various aspects by processor 32 with control patient treatment system 10.For example, processor 32 can be used for the control operation (for example speed and output) of controlled pressure generator 14.In addition, provide therein among the embodiment of control valve 20, processor 32 can be used for the operation of control valve 20 to regulate and control the flow velocity to the patient.When being provided, processor 32 can strengthen the control and the measurement of flowing to patient's output to the control of pressure generator 14 and/or valve 20 and according to the information that above-mentioned disclosure is added.
Fig. 4 has described another configuration of patient treatment system 10 in accordance with another embodiment of the present invention.Once more, identical part is endowed identical Reference numeral.More particularly, in the configuration of patient treatment system 10 illustrated in fig. 4, gas transmission system 12 does not comprise flow sensor 24.But processor module 32 also can pass through closed control valve 20, measure differential pressure (P by pressure transducer 21
Diff) and supposition (but not measure) zero flow velocity and determine atmospheric pressure according to equation (5).Based on this result, processor module 32 can be monitored the various parameters of above-mentioned pressurized breathable gas when gas transmission system 12 operations.
Will be understood that only provide above-mentioned special equation for describing purpose, expected range of the present invention comprises another algorithm of breathable gas monitoring parameter and directly do not measure atmospheric pressure that this parameter is atmospheric function.
Although based on thinking that now the most practical and preferred embodiment are to describe purpose to describe the present invention in detail, but will understand such details only is for this purpose, and the invention is not restricted to the disclosed embodiments but opposite expectation comprises the change and the equivalence that belong to accessory claim essence and scope is provided with.
Claims (28)
1. a gas transmission system (12) comprising:
Pressure generator (14) pressurizes to transmit to the patient to breathable gas (22);
Pressure transducer (21) is measured the breathable gas (22) of pressurization and the pressure reduction between the atmospheric pressure;
Flow sensor (24), measure by pressure generator (14) the standard flow rate of the pressurized breathable gas of exporting (22); And
Processor (32) is determined in atmospheric pressure, atmospheric density or the density correction factor at least one based on the standard flow rate of pressure reduction and measurement at least in part.
2. the system as claimed in claim 1 (12), wherein flow sensor (24) is a hot wire anemometer.
3. system as claimed in claim 2 (12), wherein processor (32) is triggered to determine at least one in atmospheric pressure, atmospheric density or the density correction factor when detecting the predetermined trigger incident.
4. system as claimed in claim 3 (12), wherein Yu Ding trigger event comprises the pressurized breathable gas (22) that standard flow rate is substantially zero.
5. the system as claimed in claim 1 (12) also comprises the valve (20) in pressure generator (14) downstream, and valve (20) is controlled by processor (32).
6. the system as claimed in claim 1 (12), wherein processor (32) is determined density correction factor and the standard flow rate of pressurized breathable gas be multiply by density correction factor to determine the volume flow rate of pressurized breathable gas (22).
7. the system as claimed in claim 1 (12) also comprises the temperature monitor that monitors pressurized breathable gas (22) temperature.
8. system as claimed in claim 7 (12), wherein processor (32) is also determined in atmospheric pressure, atmospheric density or the density correction factor at least one based on the temperature of pressurized breathable gas (22) to small part.
9. the system as claimed in claim 1 (12), wherein pressure generator (14) comprises aerator (38), aerator (38) also comprises:
The motor (44) relevant with aerator (38); And
The impeller (40) relevant with aerator (38), impeller (40) is driven with to breathable gas (22) pressurization by motor (44) rotation, and wherein processor (32) is also determined in atmospheric pressure, atmospheric density and the density correction factor at least one based on the rotary speed of the size of impeller (40) and drives impeller (40) to small part.
10. system as claimed in claim 9 (12) also comprises the tachometer (48) of the rotating speed that monitors drives impeller (40).
11. the system as claimed in claim 1 (12), wherein processor (32) is supposed incompressible adiabatic process that is pressurised into of breathable gas (22).
12. a gas transmission system (12) comprising:
Pressure generator (14) pressurizes to transmit to the patient to breathable gas (22);
Pressure transducer (21) is measured the breathable gas (22) of pressurization and the pressure reduction between the atmospheric pressure;
Control valve (20) is arranged on the downstream of pressure generator (14), and control valve (20) is configured and is set to control the flow velocity of pressurized breathable gas (22); And
Processor (32), control control valve (20) and is determined in atmospheric pressure, atmospheric density or the density correction factor at least one when flow velocity is substantially zero up to small part based on the pressure reduction between pressurized breathable gas (22) and the atmospheric pressure so that the flow velocity of pressure generator (14) when operation pressurized breathable gas (22) is substantially zero.
13. system as claimed in claim 12 (12) also comprises the flow sensor (24) that is arranged on pressure generator (14) downstream, flow sensor (24) is measured the standard flow rate of pressurized breathable gas (22).
14. system as claimed in claim 13 (12), wherein processor (32) is determined density correction factor and the standard flow rate of pressurized breathable gas be multiply by density correction factor to determine the volume flow rate of pressurized breathable gas (22).
15. system as claimed in claim 12 (12), wherein processor (32) is supposed incompressible adiabatic process that is pressurised into of breathable gas (22).
16. system as claimed in claim 12 (12), wherein processor (32) is based at least one comes the operation of controlled pressure generator (14) in atmospheric pressure, atmospheric density or the density correction factor.
17. a monitor transmissions is to the method for patient's pressurized breathable gas (22), this method comprises:
(a) with pressure generator (14) breathable gas (22) is pressurizeed;
(b) definite pressure that is applied to breathable gas (22) by pressure generator (14); And
(c) determine in atmospheric pressure, atmospheric density or the density correction factor at least one based on the pressure that is applied to breathable gas by pressure generator (14) to small part.
18. method as claimed in claim 17 also comprises:
Determine the standard flow rate of pressurized breathable gas (22), and wherein determining step (c) also to small part based on standard flow rate.
19. method as claimed in claim 18 is wherein by determining the standard flow rate of pressurized breathable gas (22) with flow sensor (24) measurement standard flow velocity.
20. method as claimed in claim 19, wherein flow sensor (24) is a hot wire anemometer.
21. method as claimed in claim 19 also comprises and detects the predetermined trigger incident, and determines that wherein the step of at least one is to trigger by detecting the predetermined trigger incident in atmospheric pressure, atmospheric density or the density correction factor.
22. method as claimed in claim 21, wherein Yu Ding trigger event comprises that the standard flow rate of definite pressurized breathable gas (22) is substantially zero.
23. method as claimed in claim 17 also comprises:
The flow velocity of pressurized breathable gas (22) is substantially zero, and wherein determining step (c) also is zero hypothesis based on standard flow rate to small part.
24. method as claimed in claim 23 wherein makes the standard flow rate of pressurized breathable gas (22) be substantially zero and comprises valve-off (20).
25. method as claimed in claim 17 also comprises the temperature of definite pressurized breathable gas (22).
26. method as claimed in claim 25, wherein to small part based on by pressure generator (14) the temperature of the pressure of the breathable gas that is applied to (22) and pressurized breathable gas (22) determine in atmospheric pressure, atmospheric density or the density correction factor at least one.
27. method as claimed in claim 17 also comprises:
To small part based at least one the controlled pressure generator (14) in atmospheric pressure, atmospheric density or the density correction factor.
28. method as claimed in claim 17 also comprises:
Based in atmospheric pressure, atmospheric density or the density correction factor at least one control valve (20) is controlled to small part.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96250605P | 2005-06-21 | 2005-06-21 | |
| US11/449,194 US8561611B2 (en) | 2005-06-21 | 2006-06-08 | Respiratory device measurement system |
| US11/449,194 | 2006-06-08 | ||
| PCT/US2006/023031 WO2007001836A2 (en) | 2005-06-21 | 2006-06-13 | Respiratory device measurement system |
| US60/962,506 | 2007-07-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101454040A true CN101454040A (en) | 2009-06-10 |
| CN101454040B CN101454040B (en) | 2012-06-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2006800221205A Expired - Fee Related CN101454040B (en) | 2005-06-21 | 2006-06-13 | Respiratory device measurement system |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN101454040B (en) |
| AU (1) | AU2006262588A1 (en) |
| BR (1) | BRPI0612235A2 (en) |
| CA (1) | CA2611603A1 (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102665822A (en) * | 2009-11-02 | 2012-09-12 | 3M创新有限公司 | Method of controlling a powered air purifying respirator |
| CN103781507A (en) * | 2011-08-25 | 2014-05-07 | 皇家飞利浦有限公司 | Method and apparatus for controlling ventilation therapy device |
| CN104162219A (en) * | 2013-05-16 | 2014-11-26 | 液体空气医疗系统公司 | Apparatus for artificial ventilation having an absolute pressure sensor and a differential pressure sensor |
| CN104888322A (en) * | 2010-06-01 | 2015-09-09 | 卡普尼亚公司 | Gas dispenser for dispensing accurate doses of therapeutic gas from a reservoir containing highly compressed therapeutics gas |
| CN105455814A (en) * | 2014-09-05 | 2016-04-06 | 台达电子工业股份有限公司 | Breathing device capable of detecting airflow pressure difference |
| CN110740683A (en) * | 2017-06-13 | 2020-01-31 | 罗伯特·博世有限公司 | Mouthpiece, system and method for delivering measurements of analytes in exhaled air |
| TWI690340B (en) * | 2014-12-04 | 2020-04-11 | 愛爾蘭商諾頓（沃特福德）有限公司 | Inhalation monitoring system and inhaler |
| CN113018796A (en) * | 2021-02-05 | 2021-06-25 | 中国人民解放军总医院海南医院 | Wearable equipment for lung rehabilitation |
| CN114929313A (en) * | 2019-07-30 | 2022-08-19 | 瑞思迈私人有限公司 | Method and apparatus for respiratory therapy |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2866869B1 (en) | 2012-06-29 | 2018-03-07 | ResMed Limited | Pressure sensor evaluation for respiratory apparatus |
| CN111686352B (en) * | 2019-03-15 | 2023-07-14 | 欧姆龙健康医疗事业株式会社 | Fluid supply method and fluid supply device |
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| US4870393A (en) * | 1988-04-08 | 1989-09-26 | Westinghouse Electric Corp. | Method and apparatus for determining generator ventilation system failure using two differential pressure sensors |
| SE9402537L (en) * | 1994-07-20 | 1996-01-21 | Siemens Elema Ab | Anesthesia System |
| US6644310B1 (en) * | 2000-09-29 | 2003-11-11 | Mallinckrodt Inc. | Apparatus and method for providing a breathing gas employing a bi-level flow generator with an AC synchronous motor |
-
2006
- 2006-06-13 BR BRPI0612235-3A patent/BRPI0612235A2/en active Search and Examination
- 2006-06-13 CA CA002611603A patent/CA2611603A1/en not_active Abandoned
- 2006-06-13 CN CN2006800221205A patent/CN101454040B/en not_active Expired - Fee Related
- 2006-06-13 AU AU2006262588A patent/AU2006262588A1/en not_active Abandoned
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102665822A (en) * | 2009-11-02 | 2012-09-12 | 3M创新有限公司 | Method of controlling a powered air purifying respirator |
| CN104888322A (en) * | 2010-06-01 | 2015-09-09 | 卡普尼亚公司 | Gas dispenser for dispensing accurate doses of therapeutic gas from a reservoir containing highly compressed therapeutics gas |
| CN103781507A (en) * | 2011-08-25 | 2014-05-07 | 皇家飞利浦有限公司 | Method and apparatus for controlling ventilation therapy device |
| CN104162219A (en) * | 2013-05-16 | 2014-11-26 | 液体空气医疗系统公司 | Apparatus for artificial ventilation having an absolute pressure sensor and a differential pressure sensor |
| CN104162219B (en) * | 2013-05-16 | 2017-08-25 | 液体空气医疗系统公司 | Respirator with absolute pressure transducer and differential pressure pick-up |
| CN105455814A (en) * | 2014-09-05 | 2016-04-06 | 台达电子工业股份有限公司 | Breathing device capable of detecting airflow pressure difference |
| US11141547B2 (en) | 2014-12-04 | 2021-10-12 | Norton (Waterford) Limited | Inhalation monitoring system and method |
| TWI690340B (en) * | 2014-12-04 | 2020-04-11 | 愛爾蘭商諾頓（沃特福德）有限公司 | Inhalation monitoring system and inhaler |
| TWI749475B (en) * | 2014-12-04 | 2021-12-11 | 愛爾蘭商諾頓（沃特福德）有限公司 | Systems and apparatuses for generating an expiratory measure based on an inspiratory measure, and generating alerts based on patterns in inhalation data |
| CN110740683A (en) * | 2017-06-13 | 2020-01-31 | 罗伯特·博世有限公司 | Mouthpiece, system and method for delivering measurements of analytes in exhaled air |
| US11678814B2 (en) | 2017-06-13 | 2023-06-20 | Robert Bosch Gmbh | Mouthpiece, system and method for enabling a measurement of analytes in exhaled air |
| CN114929313A (en) * | 2019-07-30 | 2022-08-19 | 瑞思迈私人有限公司 | Method and apparatus for respiratory therapy |
| CN113018796A (en) * | 2021-02-05 | 2021-06-25 | 中国人民解放军总医院海南医院 | Wearable equipment for lung rehabilitation |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101454040B (en) | 2012-06-20 |
| BRPI0612235A2 (en) | 2009-08-04 |
| AU2006262588A1 (en) | 2007-01-04 |
| CA2611603A1 (en) | 2007-01-04 |
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