CN1099645A

CN1099645A - Medicine for stopping smoking and pain

Info

Publication number: CN1099645A
Application number: CN 94104802
Authority: CN
Inventors: 陈建设
Original assignee: Individual
Current assignee: Individual
Priority date: 1994-04-27
Filing date: 1994-04-27
Publication date: 1995-03-08

Abstract

The invented medicine firstly cuts the tobacco into pieces and puts them in water to digest by pressurizing and heating, after it is naturally cooled, the residue is removed by filtering to obtain plant extraction of tobacco which is then mixed according a specific proportion with the safflower oil, alcohol, camphor and niacin tablet. Said medicine has no any irritant smell and permeates via skin into blood. The result for giving off opium is obvious, meanwhile it has obviously curative effect for rheumatic osteodynia lumbago due to pathogenic wind-dampness and swelling pain due to sprain.

Description

Medicine for stopping smoking and pain

The present invention relates to medicinal preparation, relate in particular to the medicine for stopping smoking and pain product of raw material sources in plant.

Harm of smoking, this is the fact that each smoker knows.But smoking phenomenon still is difficult to give up effectively at present, except smoker's reason itself, also since most of stop smoking medicine or instrument all be by take or use in cause serious discomfort or physiological reaction to reach the smoking cessation purpose to the smoker.Therefore many smokers are taking or are using one just to be unwilling to continue to use after twice.Disclosed a kind of quick-acting drug " Jie Yan Ling " for giving up smoking No. 88103436.3 as Chinese patent application, chosen certain medical herbs and chemical reagent exactly and be made into a kind of special liquid.This material has volatility but the sustainable abnormal smells from the patient of user, and sucking the back people easily has special physiological reaction to the abnormal smells from the patient that Nicotiana tabacum L. produces, thereby reaches the smoking cessation purpose.But this quick-acting drug " Jie Yan Ling " for giving up smoking is owing to have a kind of penetrating odor, so the smoker generally is reluctant repeatedly to use.

The purpose of this invention is to provide a kind of smoking deterent,, medicine is infiltrated in the blood, do not reach the smoking cessation purpose just now thereby the smoker is produced smoking by this medicine is directly contacted with skin.

Another object of the present invention provides a kind of analgesic, and this analgesic spreads on the affected part, to rheumatic ostalgia, soreness of waist osteodynia, sprain to swell and ache and have excellent curative.

The object of the present invention is achieved like this: get Nicotiana tabacum L. and cut into pieces, immerse in the water, the chemical analysis in the Nicotiana tabacum L. is dissolved in the water, remove the Nicotiana tabacum L. residue behind the natural cooling, it is standby that last low temperature distillation makes brown oil paste tobacco plant element; Camphora is dissolved in ethanol, evenly join in the described tobacco plant element, get safflower oil, nicotinic acid tablet and smash to pieces and add in the tobacco plant element equably and fully stir evenly; Concrete proportioning is as follows: the tobacco plant element: 77～92%, and ethanol: 6～17%, safflower oil: 1～4%, Camphora: 0.4～2%, nicotinic acid (sheet): 0.1～0.8%.

The present invention has the following advantages and good effect: 1. do not have any penetrating odor, can not make the ES smell this medicine and produce discomfort; 2. pharmaceutical compositions infiltrates blood through skin, and the smoking cessation effect is obvious; 3. to rheumatic ostalgia, soreness of waist osteodynia, sprain to swell and ache and all have good efficacy.

The present invention will be further described below in conjunction with specific embodiment, but do not limit the present invention.

At first get Nicotiana tabacum L. and cut into pieces and immersed in the water 6～12 hours, decocted 40～60 minutes through high pressure then, the temperature of decoction is preferably 121.5 ℃, the about 1KG/CM of pressure ², make the chemical analysis in the Nicotiana tabacum L. soluble in water.Treat elimination Nicotiana tabacum L. residue behind the natural cooling, carry out low temperature distillation then, until becoming brown oil paste tobacco plant element.The plain main component of the Nicotiana tabacum L. thing that makes thus has: nicotine, nornicotine, nicotelline, dl-anabasine, 2-(3-pyridyl)-1,2,3,6-tetrahydropyridine, Folium Symplocoris Caudatae ring, different Cortex querci dentatae ring, citric acid, place malic acid, caffeine acid, chlorogenic acid and other multiple organic acid.Its hot temperature is slightly poisonous, and analgesia, the old wet itching-relieving efficacies of becoming silted up that loose arranged.Ethanol is got general medicinal alcohol and is got final product, mainly as the solvent and anticorrosion, the blood vessel dilating of sterilizing.Safflower oil is general commercially available Chinese patent medicine, main effect for invigorate blood circulation, blood stasis dispelling, traumatic injury, cooling blood for hemostasis, heat-clearing and toxic substances removing, blood vessel dilating, promotion absorption.Its Main Ingredients and Appearance is as follows: white oil 10%, white Chinese tallowtree seed oil 10%, Bay leaves oil 12%, cinnamic aldehyde 3%, Oleum Terebinthinae 35%, wintergreen oil 40%.The Camphora hardship has the effect of removing toxic substances and promoting subsidence of swelling.Nicotinic acid tablet can participate in multiple metabolism process in the body, expansion small artery.Concrete proportioning is as follows: the tobacco plant element: 77～92%, and ethanol: 6～17%, safflower oil: 1～4%, Camphora: 0.4～2%, nicotinic acid (sheet): 0.1～0.8%.For promoting sweat gland secretion, expand capillary of skin and increase faint scent, also can in Nicotiana tabacum L., add a spot of Herba Menthae and Herba Schizonepetae, promptly the weight of Herba Menthae and Herba Schizonepetae accounts for below 5% of Nicotiana tabacum L., and preferably Herba Menthae and Herba Schizonepetae respectively account for 2.5%.Get ethanol during preparation and put into cup and camphorate, water proof is heated to dissolving fully, adds in the tobacco plant element for preparing equably.Get safflower oil then, nicotinic acid tablet is smashed to pieces to add equably in the tobacco plant element and is fully stirred evenly.The medicament for preparing is the brown oil paste, and aromatic odor is arranged.Ointment system can be gone in the medical rubber cream for using.Also can make airtight bottle box packing in addition, during use medicament is coated on and be subjected on treatment person's skin.Use proof according to repetition test, plaster is attached to the forearm that is subjected to treatment person (in the arm to the Neiguan acupoint place) or back (Zhong chuan is to WEIYU acupoint) is located, human body is the fastest to drug absorption, and curative effect is also best.Medicine sees through skin and evenly infiltrates in the body, makes to keep a certain amount of drug level in the body, is subjected to treatment person just to begin to occur curative effect after two weeks.That is, nauseating, tasteless reaction is arranged during smoking.Treat about 10 weeks, can make the smoker give up craving for tobacco fully.In whole therapeutic process, human body there be not any pair of effect.

Preparation example 1:

Tobacco curing grass phytochemicals is standby as stated above to get Nicotiana tabacum L..Ethanol 10 grams are put into cup, 1.5 grams that camphorate, and make it to dissolve fully, join equably then in the 85 gram tobacco plant elements.Get safflower oil 3 grams again, nicotinic acid tablet 0.5 is smashed to pieces to add equably in the described tobacco plant element and is fully stirred evenly.

Preparation example 2:

With dissolving in the Camphora 2 gram addings 20 gram ethanol, join then in the 95 gram tobacco plant elements.With safflower oil 5 grams, nicotinic acid tablet 1 gram is smashed to pieces to join equably in the tobacco plant element and is stirred evenly again.

Preparation example 3:

Camphora 0.3 gram is dissolved in the 5 gram ethanol, joins then in the 70 gram tobacco plant elements.Nicotinic acid tablet 0.1 gram that again safflower oil 1 is restrained and smashs to pieces joins in the tobacco plant element and stirs.

Claims

1, a kind of medicine for stopping smoking and pain is characterized in that adopting following proportioning: the tobacco plant element: 77～92%, spill essence: and 6～17%, safflower oil: 1～4%, Camphora: 0.4～2%, nicotinic acid (sheet): 0.1～0.8%.

2, medicine for stopping smoking and pain according to claim 1 is characterized in that described tobacco plant element is by with Nicotiana tabacum L. and account for Herba Menthae and the Herba Schizonepetae of Nicotiana tabacum L. below 5% and cut into pieces to immerse in the water and through steaming and decocting under high pressure and make.

3, as medicine for stopping smoking and pain as described in the claim 2, it is characterized in that Herba Menthae and Herba Schizonepetae respectively account for 2.5% of Nicotiana tabacum L..