CN1098092C - Rheumatism capsule - Google Patents
Rheumatism capsule Download PDFInfo
- Publication number
- CN1098092C CN1098092C CN98117711A CN98117711A CN1098092C CN 1098092 C CN1098092 C CN 1098092C CN 98117711 A CN98117711 A CN 98117711A CN 98117711 A CN98117711 A CN 98117711A CN 1098092 C CN1098092 C CN 1098092C
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- Prior art keywords
- radix
- capsule
- present
- bailey myospalax
- myospalax born
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- Expired - Lifetime
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- 239000002775 capsule Substances 0.000 title claims abstract description 16
- 241001526348 Myospalax Species 0.000 claims description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 9
- 239000000843 powder Substances 0.000 claims description 6
- 239000002994 raw material Substances 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 3
- 239000006071 cream Substances 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 238000000643 oven drying Methods 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 238000010992 reflux Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 239000008187 granular material Substances 0.000 claims description 2
- 238000011084 recovery Methods 0.000 claims description 2
- 208000006820 Arthralgia Diseases 0.000 abstract description 7
- 208000002193 Pain Diseases 0.000 abstract description 6
- 208000025747 Rheumatic disease Diseases 0.000 abstract description 6
- 230000000552 rheumatic effect Effects 0.000 abstract description 6
- 201000003068 rheumatic fever Diseases 0.000 abstract description 6
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract description 6
- 230000036407 pain Effects 0.000 abstract description 5
- 230000008961 swelling Effects 0.000 abstract description 4
- 238000005516 engineering process Methods 0.000 abstract description 2
- 210000003205 muscle Anatomy 0.000 abstract description 2
- 244000061520 Angelica archangelica Species 0.000 abstract 1
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 241000510667 Conioselinum Species 0.000 abstract 1
- 241000501743 Gentiana macrophylla Species 0.000 abstract 1
- 201000005569 Gout Diseases 0.000 abstract 1
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 241000229179 Ledebouriella Species 0.000 abstract 1
- 241000133134 Saussurea Species 0.000 abstract 1
- 241001533104 Tribulus terrestris Species 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 229940126678 chinese medicines Drugs 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 230000008407 joint function Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 10
- 230000000694 effects Effects 0.000 description 8
- 210000002435 tendon Anatomy 0.000 description 6
- 230000017531 blood circulation Effects 0.000 description 5
- 210000003414 extremity Anatomy 0.000 description 5
- 230000001737 promoting effect Effects 0.000 description 5
- YRAQEMCYCSSHJG-NSHDSACASA-N (S)-columbianetin Chemical compound C1=CC(=O)OC2=C1C=CC1=C2C[C@@H](C(C)(O)C)O1 YRAQEMCYCSSHJG-NSHDSACASA-N 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- FAMPSKZZVDUYOS-OWEBEESNSA-N (1e,4z,8e)-2,6,6,9-tetramethylcycloundeca-1,4,8-triene Chemical compound C\C1=C/CC(C)(C)\C=C/C\C(C)=C\CC1 FAMPSKZZVDUYOS-OWEBEESNSA-N 0.000 description 2
- JSNRRGGBADWTMC-UHFFFAOYSA-N (6E)-7,11-dimethyl-3-methylene-1,6,10-dodecatriene Chemical compound CC(C)=CCCC(C)=CCCC(=C)C=C JSNRRGGBADWTMC-UHFFFAOYSA-N 0.000 description 2
- -1 Coumarins chemical compounds Chemical class 0.000 description 2
- YRAQEMCYCSSHJG-UHFFFAOYSA-N Tetrahydro-oroselol Natural products C1=CC(=O)OC2=C1C=CC1=C2CC(C(C)(O)C)O1 YRAQEMCYCSSHJG-UHFFFAOYSA-N 0.000 description 2
- FAMPSKZZVDUYOS-UHFFFAOYSA-N alpha-Caryophyllene Natural products CC1=CCC(C)(C)C=CCC(C)=CCC1 FAMPSKZZVDUYOS-UHFFFAOYSA-N 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 206010003246 arthritis Diseases 0.000 description 2
- 229930006722 beta-pinene Natural products 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- QBNFBHXQESNSNP-UHFFFAOYSA-N humulene Natural products CC1=CC=CC(C)(C)CC=C(/C)CCC1 QBNFBHXQESNSNP-UHFFFAOYSA-N 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000002075 main ingredient Substances 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- WTARULDDTDQWMU-UHFFFAOYSA-N β-pinene Chemical compound C1C2C(C)(C)C1CCC2=C WTARULDDTDQWMU-UHFFFAOYSA-N 0.000 description 2
- WTARULDDTDQWMU-RKDXNWHRSA-N (+)-β-pinene Chemical compound C1[C@H]2C(C)(C)[C@@H]1CCC2=C WTARULDDTDQWMU-RKDXNWHRSA-N 0.000 description 1
- WTARULDDTDQWMU-IUCAKERBSA-N (-)-Nopinene Natural products C1[C@@H]2C(C)(C)[C@H]1CCC2=C WTARULDDTDQWMU-IUCAKERBSA-N 0.000 description 1
- JSNRRGGBADWTMC-QINSGFPZSA-N (E)-beta-Farnesene Natural products CC(C)=CCC\C(C)=C/CCC(=C)C=C JSNRRGGBADWTMC-QINSGFPZSA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- YXEZXGJYPKMKEJ-UHFFFAOYSA-N Gentianin Natural products C=Cc1cc2CCOC(=O)c2cn1 YXEZXGJYPKMKEJ-UHFFFAOYSA-N 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- HPUXDMUGCAWDFW-UHFFFAOYSA-N Osthole Natural products COc1ccc2CCC(=O)Oc2c1C=CC(=O)C HPUXDMUGCAWDFW-UHFFFAOYSA-N 0.000 description 1
- 241000208317 Petroselinum Species 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 241000238370 Sepia Species 0.000 description 1
- 208000038016 acute inflammation Diseases 0.000 description 1
- 230000006022 acute inflammation Effects 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- XCPQUQHBVVXMRQ-UHFFFAOYSA-N alpha-Fenchene Natural products C1CC2C(=C)CC1C2(C)C XCPQUQHBVVXMRQ-UHFFFAOYSA-N 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000000146 antalgic effect Effects 0.000 description 1
- 230000001760 anti-analgesic effect Effects 0.000 description 1
- 230000000702 anti-platelet effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 230000002917 arthritic effect Effects 0.000 description 1
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N benzo-alpha-pyrone Natural products C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 description 1
- YSNRTFFURISHOU-UHFFFAOYSA-N beta-farnesene Natural products C=CC(C)CCC=C(C)CCC=C(C)C YSNRTFFURISHOU-UHFFFAOYSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 235000010418 carrageenan Nutrition 0.000 description 1
- 229920001525 carrageenan Polymers 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- DQISGWRLCDLKJI-UHFFFAOYSA-N columbianetin Natural products C1=CC(=O)OC2=C(C(C(C(C)(O)C)O3)O)C3=CC=C21 DQISGWRLCDLKJI-UHFFFAOYSA-N 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 235000001671 coumarin Nutrition 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 210000002683 foot Anatomy 0.000 description 1
- LCWMKIHBLJLORW-UHFFFAOYSA-N gamma-carene Natural products C1CC(=C)CC2C(C)(C)C21 LCWMKIHBLJLORW-UHFFFAOYSA-N 0.000 description 1
- XOXYHGOIRWABTC-UHFFFAOYSA-N gentisin Chemical compound C1=C(O)C=C2C(=O)C3=C(O)C=C(OC)C=C3OC2=C1 XOXYHGOIRWABTC-UHFFFAOYSA-N 0.000 description 1
- 210000000548 hind-foot Anatomy 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 210000005087 mononuclear cell Anatomy 0.000 description 1
- 229940021584 osthol Drugs 0.000 description 1
- MBRLOUHOWLUMFF-UHFFFAOYSA-N osthole Chemical compound C1=CC(=O)OC2=C(CC=C(C)C)C(OC)=CC=C21 MBRLOUHOWLUMFF-UHFFFAOYSA-N 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 235000011197 perejil Nutrition 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 238000006748 scratching Methods 0.000 description 1
- 230000002393 scratching effect Effects 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a rheumatism capsule which is prepared from eight tibetan and Chinese medicines of selonggu, saussurea, largeleaf gentian roots, ledebouriella roots, doubleteeth pubesscent angelica roots, puncturevine caltrop fruits, cassia twigs and hemlock parsley by modern science and technology. The present invention has the efficiencies of dispelling cold, removing humidity, relieving rigidity of muscle, activating collaterals, eliminating swelling and alleviating pains, and is used for treating rheumatic gout, numb limbs, swelling joints, rheumatic arthritis, rheumatoid arthritis, etc. The present invention can obviously lighten arthralgia and swelling degree and improve joint functions in the process of treating arthromyodynia and preventing the pathogeny of rheumatism.
Description
The present invention relates to a kind of rheumatism capsule, relate in particular to a kind of treatment rheumatic arthralgia, numb limbs and tense tendons, rheumatic arthritis, rheumatoid arthritic Tibetan medicine one brilliant pearl rheumatism capsule.
Rheumatism, especially rheumatism, rheumatoid arthritis give many in, gerontal patient's life brings inconvenience, numb limbs and tense tendons, rheumatic arthralgia, arthroncus at every moment are stranded is scratching them, many dosage forms is arranged at present because side effect is big or use is inconvenient and brings a lot of inconvenience to the patient.So it is easy all to wish to develop the above-mentioned disease of a kind of treatment faster in the society, and the cure rate height, the specific drug that has no side effect urgently.
The object of the present invention is to provide a kind of rheumatism capsule, particularly can treat the novel drugs of rheumatic arthralgia, numb limbs and tense tendons, rheumatic arthritis, rheumatoid arthritis, and cure rate height, have no side effect----brilliant pearl rheumatism capsule.
The objective of the invention is that original like this preparation technology realizes: Bailey Myospalax Born is pulverized a little, ordinary water lixiviate three times, after the filtration, extracting solution merges and is condensed into thick paste, and oven drying at low temperature is ground into powder.Herba Saussureae Involueratae, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Radix Angelicae Pubescentis, Ramulus Cinnamomi, Fructus Tribuli, Rhizoma Chuanxiong 60-75% alcohol reflux three times, merge extractive liquid, behind the recovery ethanol, is condensed into the thick paste shape, bakes dried cream, pulverizes, and merges with the Bailey Myospalax Born powder, adds adjuvant and granulates.Make capsule then.Its feature also is above unique preparation process and raw materials in part by weight, and is specific as follows:
Bailey Myospalax Born 400-600g
Herba Saussureae Involueratae 100-200g
Radix Gentianae Macrophyllae 190-290g
Radix Saposhnikoviae 190-290g
Radix Angelicae Pubescentis 200-400g
Ramulus Cinnamomi 190-290g
Fructus Tribuli 200-400g
Rhizoma Chuanxiong 200-400g.
Its feature of the brilliant pearl rheumatism capsule of the present invention is that also its raw materials in part by weight is preferably:
Bailey Myospalax Born 500.0g
Herba Saussureae Involueratae 150.0g
Radix Gentianae Macrophyllae 240.0g
Radix Saposhnikoviae 240.0g
Radix Angelicae Pubescentis 300.0g
Ramulus Cinnamomi 240.0g
Fructus Tribuli 300.0g
Rhizoma Chuanxiong 300.0g.
A kind of rheumatism capsule of the present invention can be treated rheumatic arthralgia, numb limbs and tense tendons, arthroncus, rheumatic arthritis, rheumatoid arthritis.Its treatment is convenient and cure rate is high, have no side effect.
Below in conjunction with example explanation the present invention, the scheme of embodiment described here does not limit the present invention, one of skill in the art can make improvements and change according to spirit of the present invention, described these improvement and variation all should be considered as within the scope of the invention, and scope and spirit of the present invention are limited by claim.
Embodiment:
Get: Bailey Myospalax Born 500.0g
Herba Saussureae Involueratae 150.0g
Radix Gentianae Macrophyllae 240.0g
Radix Saposhnikoviae 240.0g
Radix Angelicae Pubescentis 300.0g
Ramulus Cinnamomi 240.0g
Fructus Tribuli 300.0g
Rhizoma Chuanxiong 300.0g.
And Bailey Myospalax Born pulverized a little, ordinary water lixiviate three times, after the filtration, extracting solution merges and is condensed into thick paste, and oven drying at low temperature is ground into powder.Herba Saussureae Involueratae, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Radix Angelicae Pubescentis, Ramulus Cinnamomi, Fructus Tribuli, Rhizoma Chuanxiong be with 65% alcohol reflux three times, merge extractive liquid,, reclaim ethanol after, be condensed into the thick paste shape, bake dried cream, pulverize, merge with the Bailey Myospalax Born powder, add that adjuvant is made sepia, gas perfume (or spice) is different, 1000 capsules of bitter in the mouth.
A kind of rheumatism capsule of the present invention can be treated rheumatic arthralgia, numb limbs and tense tendons, arthroncus, rheumatic arthritis, rheumatoid arthritis.It treats convenient, can obviously ease the pain and improve function of joint and cure rate height.
On the existing at home Tibetan medicine of the present invention basis, help formulated with famous and precious Tibetan medicine and Chinese medicine, thereby traditional Tibetan medicine is formed through modern pharmaceutical skill letter is refining, use that the brilliant pearl rheumatism capsule treatment of the present invention rheumatism can obviously ease the pain, the swelling degree.Turning out cloudy of reduction of antagonism " 0 " value (ASO) and rheumatoid factor (RF) all has obvious kind to advance effect.
Bailey Myospalax Born:
The bone collagen of Bailey Myospalax Born is very similar to Colla Os Tigris, and rat formaldehyde and albumen arthritis are had remarkable inhibitory action.Its function is similar to Os Tigris, and effects such as expelling wind to alleviate pain, strengthening the tendons and bones, strong waist knee joint, the meridians of living are arranged.
Herba Saussureae Involueratae:
Main Ingredients and Appearance---flavone compound, as Ke Liyi element-7-0-β-D-glycoside, apiolin-7-0-β-D-glycoside, luteolin-7-0-β-D-glycoside, mountain Quercetin-7-0-β-D-glycoside etc., and nopinene (β-pinene), β-farnesene (β-farnsene), α-caryophyllene (α-caryophyllene) etc., to rat Ovum Gallus domesticus album joint acute inflammation, and formaldehyde-caused rat hind paw inflammation has tangible antagonism.Functions such as Herba Saussureae Involueratae has dispelling cold and removing dampness, promoting blood circulation to remove obstruction in the collateral, anti-inflammatory and antalgic, strong muscle is supporing yang.
Radix Gentianae Macrophyllae:
Wind-expelling pain-stopping, clearing away the hectic fever, channels sootheing and network vessel quickening; Gentianin, second, the third three kinds of alkaloids can alleviate the arthroncus degree to the rat albumen arthritis, and the rat paw edema that mice ear that Oleum Tiglii is caused and carrageenin cause has certain antiinflammatory, analgesic activity.
Radix Angelicae Pubescentis:
Nine kinds of Coumarins chemical compounds such as Main Ingredients and Appearance-umbelliprenin, methoxyl group parsley element (Osthol), Columbianedin, Columbianetin (+)-Columbianetin. have antiplatelet collection and anti-inflammatory and analgesic effect.
Rhizoma Chuanxiong:
Blood circulation promoting and blood stasis dispelling, invigorating qi and dredging collateral are led the gathering between mononuclear cell and platelet.
Ramulus Cinnamomi:
Temperature promoting blood circulation, dispersing cold for relieving pain.
Fructus Tribuli:
Promoting blood circulation by removing wind.
Radix Saposhnikoviae:
Power with the cold expelling of inducing sweat, relieving convulsion.The effect of performance " expelling wind and cold, promoting blood circulation to remove obstruction in the collateral, remove arthralgia chiefly caused by damp pathogen ".
Through clinical investigation:
This product medicine is tried out observation through Qinghai Province institute of traditional Chinese medicine, Affiliated Hospital of Qinghai Medicine College, the People's Hospital, Qinghai Province.Get three hospital's cases, unified rheumatic arthritis, diagnosis of rheumatoid arthritis standard, and with WANGBI CHONGJI as matched group, the contrast therapy effect:
(1) curative effect relatively: the treatment group of using product of the present invention is cured 18 examples in 175 examples, account for 10.28%; Produce effects 60 examples account for 34.29%; Effective 78 examples account for 44.57%; Invalid 19 examples account for 10.86%, total effective rate 89.14%.
Compare with matched group, the latter cures 3 examples, accounts for 5.88%; Produce effects 8 examples account for 15.69%; Effective 28 examples account for 51.90%; Invalid 12 examples account for 23.53%; Total effective rate 79.47% has notable difference.
(2) to the influence of function of joint:
Use the treatment group of product of the present invention, in 32 examples, divide level Four, I level 40 examples before the treatment, II level 65 examples, III level 24 examples, IV level 3 examples, treatment back I level accounts for 91 examples, II level 18 examples, III level 13 examples, IV level 2 examples.Compare with matched group, the latter 36 routine patients divide level Four, I level 4 examples before the treatment, II level 20 examples, III level 11 examples, IV level 1 example.Treatment back I level 14 examples, II level 13 examples, III level 6 examples, IV level 1 example.
Claims (3)
1, the rheumatismal capsule of a kind of treatment is characterized in that it is prepared by the following weight proportion raw material:
Bailey Myospalax Born 400-600g
Herba Saussureae Involueratae 100-200g
Radix Gentianae Macrophyllae 190-290g
Radix Saposhnikoviae 190-290g
Radix Angelicae Pubescentis 200-400g
Ramulus Cinnamomi 190-290g
Fructus Tribuli 200-400g
Rhizoma Chuanxiong 200-400g.
2, the described capsule of claim 1 is characterized in that it is prepared by the following weight proportion raw material:
Bailey Myospalax Born 500.0g
Herba Saussureae Involueratae 150.0g
Radix Gentianae Macrophyllae 240.0g
Radix Saposhnikoviae 240.0g
Radix Angelicae Pubescentis 300.0g
Ramulus Cinnamomi 240.0g
Fructus Tribuli 300.0g
Rhizoma Chuanxiong 300.0g.
3, the described capsular preparation method of claim 1 or claim 2 is characterized in that, Bailey Myospalax Born is pulverized a little, and ordinary water lixiviate three times, after the filtration, the extracting solution merging is condensed into thick paste, and oven drying at low temperature is ground into powder.Herba Saussureae Involueratae, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Radix Angelicae Pubescentis, Ramulus Cinnamomi, Fructus Tribuli, Rhizoma Chuanxiong 60-75% alcohol reflux three times, merge extractive liquid, behind the recovery ethanol, is condensed into the thick paste shape, bakes dried cream, pulverizes, and merges with the Bailey Myospalax Born powder, adds adjuvant and granulates.Make capsule then.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98117711A CN1098092C (en) | 1998-08-31 | 1998-08-31 | Rheumatism capsule |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98117711A CN1098092C (en) | 1998-08-31 | 1998-08-31 | Rheumatism capsule |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1207944A CN1207944A (en) | 1999-02-17 |
| CN1098092C true CN1098092C (en) | 2003-01-08 |
Family
ID=5225656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98117711A Expired - Lifetime CN1098092C (en) | 1998-08-31 | 1998-08-31 | Rheumatism capsule |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1098092C (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100540033B1 (en) * | 2002-01-18 | 2005-12-29 | 주식회사 팬제노믹스 | Crude Drug Compositions for treating or preventing arthritic diseases and the process for preparing them |
| CN106177699A (en) * | 2016-08-22 | 2016-12-07 | 曹蕊 | Rheumatism capsule |
| CN109172637B (en) * | 2018-08-21 | 2021-04-09 | 青海晶珠藏药高新技术产业股份有限公司 | Preparation method of capsule for treating rheumatism |
| CN109045141A (en) * | 2018-10-30 | 2018-12-21 | 闫癸江 | Chinese medicine composition, preparation and application |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1079161A (en) * | 1993-05-11 | 1993-12-08 | 柳海峰 | Medicine powder " Qushizhitongsan " for eliminating wetness-evil in body and analgesic |
| CN1099983A (en) * | 1993-09-09 | 1995-03-15 | 袁双田 | Medicine for treating rheumatoid or rheumatic arthritis and hyperosteogeny, and method for preparing same |
-
1998
- 1998-08-31 CN CN98117711A patent/CN1098092C/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1079161A (en) * | 1993-05-11 | 1993-12-08 | 柳海峰 | Medicine powder " Qushizhitongsan " for eliminating wetness-evil in body and analgesic |
| CN1099983A (en) * | 1993-09-09 | 1995-03-15 | 袁双田 | Medicine for treating rheumatoid or rheumatic arthritis and hyperosteogeny, and method for preparing same |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1207944A (en) | 1999-02-17 |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Beijing Jingzhu Pharmaceutical Enterprise Management Limited Assignor: Li Fangrui Contract fulfillment period: 2007.2.20 to 2013.2.20 Contract record no.: 2009110000016 Denomination of invention: Rheumatism capsule Granted publication date: 20030108 License type: Exclusive license Record date: 2009.3.13 |
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| LIC | Patent licence contract for exploitation submitted for record |
Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2007.2.20 TO 2013.2.20; CHANGE OF CONTRACT Name of requester: BEIJING JINGZHU MEDICINE ENTERPRISE MANAGEMENT CO. Effective date: 20090313 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20151111 Address after: 810008 Qinghai biological science and Technology Industrial Park, Chengbei District, Qinghai, 36, No. three, Xining Road Patentee after: Qinghai jingzhuzangyao high-tech industry Limited by Share Ltd Address before: 100062 Beijing city Chong Street No. 5-4 new world Taihua apartment block A room 510 Patentee before: Li Fangrui |
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| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20030108 |