CN1096218A - A kind of Chinese patent medicine and production method thereof for the treatment of the chronic diarrhea chronic dysentery - Google Patents
A kind of Chinese patent medicine and production method thereof for the treatment of the chronic diarrhea chronic dysentery Download PDFInfo
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- CN1096218A CN1096218A CN94100983A CN94100983A CN1096218A CN 1096218 A CN1096218 A CN 1096218A CN 94100983 A CN94100983 A CN 94100983A CN 94100983 A CN94100983 A CN 94100983A CN 1096218 A CN1096218 A CN 1096218A
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- radix
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- rhizoma
- chinese patent
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- 239000003814 drug Substances 0.000 title claims abstract description 33
- 206010012735 Diarrhoea Diseases 0.000 title claims abstract description 15
- 208000019902 chronic diarrheal disease Diseases 0.000 title claims abstract description 11
- 230000001684 chronic effect Effects 0.000 title claims abstract description 11
- 208000001848 dysentery Diseases 0.000 title claims abstract description 11
- 238000011282 treatment Methods 0.000 title claims abstract description 7
- 238000004519 manufacturing process Methods 0.000 title description 7
- 229940079593 drug Drugs 0.000 claims abstract description 11
- 241000756943 Codonopsis Species 0.000 claims abstract description 9
- 239000009636 Huang Qi Substances 0.000 claims abstract description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 9
- 239000000843 powder Substances 0.000 claims abstract description 9
- 239000002775 capsule Substances 0.000 claims abstract description 4
- 239000007788 liquid Substances 0.000 claims abstract description 4
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims description 8
- 244000080767 Areca catechu Species 0.000 claims description 8
- 235000006226 Areca catechu Nutrition 0.000 claims description 8
- 241000218176 Corydalis Species 0.000 claims description 8
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims description 8
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 8
- 238000003756 stirring Methods 0.000 claims description 5
- 239000012141 concentrate Substances 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 229920002472 Starch Polymers 0.000 claims description 3
- 238000005242 forging Methods 0.000 claims description 3
- 239000008187 granular material Substances 0.000 claims description 3
- 235000019698 starch Nutrition 0.000 claims description 3
- 239000008107 starch Substances 0.000 claims description 3
- 235000021419 vinegar Nutrition 0.000 claims description 3
- 239000000052 vinegar Substances 0.000 claims description 3
- 238000012216 screening Methods 0.000 claims description 2
- 239000002994 raw material Substances 0.000 abstract description 2
- 238000010298 pulverizing process Methods 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 210000000952 spleen Anatomy 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 201000010099 disease Diseases 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 210000003734 kidney Anatomy 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 230000001105 regulatory effect Effects 0.000 description 3
- 230000003014 reinforcing effect Effects 0.000 description 3
- 239000010425 asbestos Substances 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 229910052895 riebeckite Inorganic materials 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 208000004429 Bacillary Dysentery Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 206010017915 Gastroenteritis shigella Diseases 0.000 description 1
- 229920001131 Pulp (paper) Polymers 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 239000003212 astringent agent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 206010009887 colitis Diseases 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 230000002439 hemostatic effect Effects 0.000 description 1
- 229960003444 immunosuppressant agent Drugs 0.000 description 1
- 230000001861 immunosuppressant effect Effects 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 208000002551 irritable bowel syndrome Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 238000005453 pelletization Methods 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 201000005113 shigellosis Diseases 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000002636 symptomatic treatment Methods 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Medicines Containing Plant Substances (AREA)
Abstract
A kind of is the Chinese patent medicine that raw material is made with 14 kinds of Chinese crude drugs such as Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, is 98.42% for the effective percentage for the treatment of chronic diarrhea chronic dysentery disease.Respectively through pulverizing, decoct, concentrating, can make tablet, powder, capsule, oral liquid to former medicine.
Description
The present invention relates to a kind of is Chinese patent medicine and the production method thereof that raw material is made with the several kinds of Chinese medicinal materials.Specifically, be a kind of Chinese patent medicine and the production method thereof of treatment chronic diarrhea chronic dysentery disease card.
The Chinese medicine meaning chronic diarrhea chronic dysentery disease, the multiple disease such as chronic diarrhea, chronic bacillary dysentery, colitis, Anaphylaxis enteritis, irritable bowel syndrome that comprises modern medicine, its clinical manifestation just is characteristics with long-term stomachache, diarrhoea, mucus all, be the commonly encountered diseases among the crowd, still do not have especially effectively Therapeutic Method both at home and abroad.Doctor trained in Western medicine imposes symptomatic treatments such as medicine or immunosuppressant more, and the traditional Chinese medical science is many controls the drink-service of plan decoction with dialectical executing, and also gives the Chinese medicine and western medicine dual-purpose.All there are long, shortcoming and defect such as curative effect is of short duration, relapse rate height of treatment time in these methods, and the part method also has the big problem of side effect.Therefore, searching has the Therapeutic Method of desirable curative effect to become a task of domestic and international medical circle to the chronic diarrhea chronic dysentery.
The objective of the invention is to, provide a kind of the reliable pure Chinese medicinal preparation of chronic diarrhea chronic dysentery curative effect.It is produced easily, and taking convenience has no side effect, and helps the radical cure to this disease.
Can solve in order to following method by this task of the present invention:
One medicament composing prescription and its weight are formed
1. medicament composing prescription
Chinese medicine thinks that to the chronic diarrhea chronic dysentery is dialectical asthenia of both the spleen and kidney is basis of disease, and having loose bowels is the mark of disease.Prescription effects a permanent cure with the spleen reinforcing kidney, and assistant is to take stopgap measures, and giving consideration to both the incidental and fundamental focuses on the principle of effecting a permanent cure, and the Radix Codonopsis invigorating the spleen and regulating the stomach is got by the side, and the Rhizoma Atractylodis Macrocephalae is drying damp and strengthening spleen, Radix Astragali tonifying Qi and lifting yang, and three medicines share replenishing QI to invigorate the spleen, are principal agent; Fructus Psoraleae, Halloysitum Rubrum kidney invigorating and YANG supporting, relieving diarrhea with astringent, the Rhizoma Dioscoreae spleen invigorating of reinforcing the kidney, Rhizoma Zingiberis Preparatum warming the interior cold expelling, four medicines share can the warming the spleen kidney, aid yang qi, relieving diarrhea with astringents is tonic altogether; Radix Angelicae Sinensis, the Radix Paeoniae Alba are nourished blood and blood, and Radix Aucklandiae regulating QI is amusing, the Rhizoma Corydalis regulating QI to relieve pain, and the Radix Sanguisorbae hemostasis and dysentery-stopping, the catechu promoting tissue regeneration and ulcer healing, the removing dampness detumescence, six medicines share analgesic hemostatic, and detumescence and promoting granulation is adjuvant drug altogether; Make with its careless QI invigorating and in, coordinating the actions of various ingredients in a prescription.
By above logos and through clinical experiment repeatedly, the composition of Chinese patent medicine of the present invention is: Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Fructus Psoraleae, Rhizoma Dioscoreae, the Radix Astragali, Rhizoma Zingiberis Recens, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Corydalis, the Radix Aucklandiae, Radix Sanguisorbae, Halloysitum Rubrum, catechu, Radix Glycyrrhizae.
2. drug weight is formed
Radix Codonopsis 10-12%, the Rhizoma Atractylodis Macrocephalae (parched with bran) 4-5%, Fructus Psoraleae 7-8%, Rhizoma Dioscoreae (stir-fry) 10-12%, Radix Astragali 14-16%, Rhizoma Zingiberis Recens (big gun) 3-4%, Radix Angelicae Sinensis (stir-fry) 7-8%, the Radix Paeoniae Alba (stir-fry) 7-8%, Rhizoma Corydalis (vinegar stir-fry) 7-8%, the Radix Aucklandiae (stewing) 3-4%, Radix Sanguisorbae (stir-fry) 7-8%, Halloysitum Rubrum (forging) 3-4%, catechu 6-7%, Radix Glycyrrhizae (stir-fry) 3-4%.
Two production technologies and operational approach
The production method of tablet is as follows:
1. the part medicine is carried out grinding and processing.
Measure the Rhizoma Atractylodis Macrocephalae, Fructus Psoraleae, Rhizoma Dioscoreae, Rhizoma Zingiberis Recens, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Corydalis, the Radix Aucklandiae, Halloysitum Rubrum, catechu by this product prescription, pulverize separately sieves with the 40-120 mesh sieve, becomes the fine-powdered thing, and it is standby to stir after the mixing.
2. the part medicine is decocted and concentrates.
Decoction is measured Radix Codonopsis, the Radix Astragali, Radix Sanguisorbae, Radix Glycyrrhizae by this product prescription and is decocted with water secondary (add 10 times of amounts of water for the first time, add 8 times of amounts of water for the second time), each about 1.5 hours.Twice decoction liquor merged.
Concentrate with decocting method repeatedly under the normal pressure, or the concentrating under reduced pressure method, it is 1.35-1.40(50-60 ℃ that decoction liquor is concentrated into relative density).
Spissated decoction liquor is filtered in filtration.Filter method can use filter paper, filter paper pulp, filter stick, filter membrane, asbestos board, asbestos etc. any.
It is an amount of that figuration adds starch, dissolves standby.
3. pelletizing press sheet
Standby concentrated decoction liquor is added in the standby fine powder, stir, make granule, again tablet forming.
This product also can be made into powder, capsule, oral liquid.The method of making powder is that the equal crushing screening of all the components in the prescription is stirred.Powder equivalent branch packed into be capsule in the capsulae vacuus.The equal decoction filtering equivalent of all the components in prescription branch packed into be oral liquid in the corresponding container.
Through 314 routine chronic diarrhea chronic dysentery cases being used Chinese patent medicine clinical treatment observation research of the present invention, effective percentage is 98.42%; Matched group 102 examples, the traditional Chinese patent medicine reinforcing spleen and benefiting intestine pill for curing that uses Guangzhou Chenliji Pharmaceutical Factory to produce, effective percentage is 88.23%.Learn processing by statistics for two groups, the difference of highly significant is arranged.
Embodiment is following, and the invention will be further described with the example of producing tablet.
1. get the Rhizoma Atractylodis Macrocephalae (parched with bran) 200 grams, Fructus Psoraleae 350 grams, Rhizoma Dioscoreae (stir-fry) 500 grams, Rhizoma Zingiberis Recens (big gun) 150 grams, Radix Angelicae Sinensis (stir-fry) 350 grams, the Radix Paeoniae Alba (stir-fry) 350 grams, Rhizoma Corydalis (vinegar stir-fry) 350 grams, the Radix Aucklandiae (stewing) 150 grams, Halloysitum Rubrum (forging) 150 grams, catechu 300 grams, pulverize separately, sieve with 80 mesh sieves, become the fine-powdered thing, it is standby to stir after the mixing.
2. get Radix Codonopsis 500 grams, the Radix Astragali 700 grams, Radix Sanguisorbae (stir-fry) 350 grams, Radix Glycyrrhizae (stir-fry) 150 grams, add 10 times of amounts of water, straight fire decocted 1.5 hours, got decoction liquor.Add 8 times of amounts of water again, straight fire decocted 1.5 hours, got decoction liquor.Twice decoction liquor merged.With decocting method repeatedly under the normal pressure, decoction liquor is concentrated into 2000 milliliters, its relative density is 1.40(50 ℃).With spissated decoction liquor filter paper filtering, add appropriate amount of starch, dissolve standby.
3. standby concentrated decoction liquor is added in the standby fine powder, stir, make granule, again tablet forming.
An above-mentioned inventory is made 10000 in tablet altogether, and every contains crude drug and is equivalent to 0.455 gram.The adult takes each four, every day three times.
Claims (6)
1, a kind of Chinese patent medicine for the treatment of chronic diarrhea chronic dysentery disease is characterized in that, its Chinese medicinal components comprises Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Fructus Psoraleae, Rhizoma Dioscoreae, the Radix Astragali, Rhizoma Zingiberis Recens, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Corydalis, the Radix Aucklandiae, Radix Sanguisorbae, Halloysitum Rubrum, catechu, Radix Glycyrrhizae.
2, Chinese patent medicine according to claim 1 is characterized in that, the weight of described Chinese medicinal components consists of, Radix Codonopsis 10-12%, the Rhizoma Atractylodis Macrocephalae (parched with bran) 4-5%, Fructus Psoraleae 7-8%, Rhizoma Dioscoreae (stir-fry) 10-12%, Radix Astragali 14-16%, Rhizoma Zingiberis Recens (big gun) 3-4%, Radix Angelicae Sinensis (stir-fry) 7-8%, the Radix Paeoniae Alba (stir-fry) 7-8%, Rhizoma Corydalis (vinegar stir-fry) 7-8%, the Radix Aucklandiae (stewing) 3-4%, Radix Sanguisorbae (stir-fry) 7-8%, Halloysitum Rubrum (forging) 3-4%, catechu 6-7%, Radix Glycyrrhizae (stir-fry) 3-4%.
3, according to claim 1 and 2 described Chinese patent medicines, it is characterized in that to the Rhizoma Atractylodis Macrocephalae in the component, Fructus Psoraleae, Rhizoma Dioscoreae, Rhizoma Zingiberis Recens, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Corydalis, the Radix Aucklandiae, Halloysitum Rubrum, catechu, pulverize separately sieves; Radix Codonopsis in the component, the Radix Astragali, Radix Sanguisorbae, Radix Glycyrrhizae are mixed decoction, concentrate, filter, add appropriate amount of starch; To concentrate decoction liquor again and join in the standby fine powder, stir, make granule, tablet forming.
4, according to claim 1 and 2 described Chinese patent medicines, it is characterized in that, the equal crushing screening of all the components in the prescription is stirred make powder.
5, according to claim 1,2 and 4 described Chinese patent medicines, it is characterized in that, powder equivalent branch is packed into make capsule in the capsulae vacuus.
According to claim 1 and 2 described Chinese patent medicines, it is characterized in that 6, to the equal decoction filtering of all the components in the prescription, the equivalent branch is packed into and made oral liquid in the corresponding container.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN94100983A CN1096218A (en) | 1994-02-05 | 1994-02-05 | A kind of Chinese patent medicine and production method thereof for the treatment of the chronic diarrhea chronic dysentery |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN94100983A CN1096218A (en) | 1994-02-05 | 1994-02-05 | A kind of Chinese patent medicine and production method thereof for the treatment of the chronic diarrhea chronic dysentery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1096218A true CN1096218A (en) | 1994-12-14 |
Family
ID=5029976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN94100983A Pending CN1096218A (en) | 1994-02-05 | 1994-02-05 | A kind of Chinese patent medicine and production method thereof for the treatment of the chronic diarrhea chronic dysentery |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1096218A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057680C (en) * | 1996-02-01 | 2000-10-25 | 王维 | Traditional Chinese medicine for curing dysentery |
| CN1323679C (en) * | 2002-08-06 | 2007-07-04 | 蒋树孝 | Medicine for treating enteron diseases |
| CN101485873B (en) * | 2009-03-05 | 2011-11-23 | 赖福平 | Tonic and intestine-benefiting Chinese herbal compound preparation |
| CN103877545A (en) * | 2014-03-15 | 2014-06-25 | 青岛绿曼生物工程有限公司 | Traditional Chinese medicinal composition for treating poultry diarrhea and preparation method thereof |
| CN107296947A (en) * | 2017-06-30 | 2017-10-27 | 张登晶 | A kind of Chinese medicine preparation for treating chronic diarrhea |
-
1994
- 1994-02-05 CN CN94100983A patent/CN1096218A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057680C (en) * | 1996-02-01 | 2000-10-25 | 王维 | Traditional Chinese medicine for curing dysentery |
| CN1323679C (en) * | 2002-08-06 | 2007-07-04 | 蒋树孝 | Medicine for treating enteron diseases |
| CN101485873B (en) * | 2009-03-05 | 2011-11-23 | 赖福平 | Tonic and intestine-benefiting Chinese herbal compound preparation |
| CN103877545A (en) * | 2014-03-15 | 2014-06-25 | 青岛绿曼生物工程有限公司 | Traditional Chinese medicinal composition for treating poultry diarrhea and preparation method thereof |
| CN103877545B (en) * | 2014-03-15 | 2016-08-17 | 青岛众志合才智能科技有限公司 | Chinese medicine composition for the treatment of avian dysentery and preparation method thereof |
| CN107296947A (en) * | 2017-06-30 | 2017-10-27 | 张登晶 | A kind of Chinese medicine preparation for treating chronic diarrhea |
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