CN1090947C - Patch powder composition and wet cloth preparation thereof - Google Patents

Abstract

The invention provides a paste powder composition, which is prepared by grinding 30-45 wt% of one or more raw traditional Chinese medicine materials selected from the group consisting of peach kernels, apricot kernels, white pepper, sticky rice and yarrow which have the function of promoting blood circulation, 55-70 wt% of one or more raw traditional Chinese medicine materials selected from the group consisting of centipede, saffron, honeysuckle, rhubarb, bezoar, licorice powder, salvia miltiorrhiza, ligusticum wallichii, ground beetle, achyranthes and cyathula root which have the function of expelling toxin, and one or more raw traditional Chinese medicine materials selected from the group consisting of vinegar and acetate which have the function of softening cuticle, medicinal cyathula root and rehmannia root (the amount is about 0.5-4 wt% of the total amount of the two), adding a tackifier if necessary, and uniformly mixing the mixture with vinegar, water or wine to form paste for paste application.

Description

Patch powder composition and wet cloth preparation thereof

The present invention relates to a sticking powder composition, especially one or more raw materials of traditional Chinese medicine selected from the group consisting of peach kernels, southern almonds, white pepper, glutinous rice and white yarrow, which have the function of opening blood passages. ～45% by weight, and one selected from the group consisting of centipede, saffron, honeysuckle, rhubarb, bezoar, licorice powder, salvia miltiorrhiza, Chuanxiong, wood turtle, achyranthes bidentata and tragacanth with detoxification function or 55% to 70% by weight of more than one raw material of traditional Chinese medicine, and one or more substances selected from the group consisting of vinegar, acetates, Chuanqi and Shengdi which have the function of softening the cuticle (the amount is The total amount of the first two is about 0.5-4% by weight), after being ground, adding a thickening agent if necessary, mixing it with vinegar, water or sprinkling into a paste, and the application powder prepared by the raw materials of traditional Chinese medicine is available For application, it can be applied to a specific part of the human skin or the corresponding part of the sensory organs to achieve the therapeutic purpose of dredging the meridian and activating collaterals, strengthening the body and eliminating pathogenic factors, and promoting qi and blood circulation.

Generally, as the middle-aged and elderly people grow older, their physical strength, vigor and physiological functions gradually decline and degenerate, their resistance to foreign viruses weakens, and their ability to adapt to sudden changes in climate and environment is not as good as before. How to improve the resistance of middle-aged and elderly people? Disease ability and adaptation to sudden changes in water and soil are the main tasks of health care for middle-aged and elderly people. Although the medical circles all over the world are making efforts in this direction and researching and developing chemical pharmaceutical products, the prescriptions used include single prescriptions and compound prescriptions, and the dosage forms include granules, injections, tablets, etc. However, their synthesis and production are very complicated and often accompanied by There are side effects, and damage to the gastrointestinal tract and liver, so it is still not ideal.

In particular, arteriosclerosis is one of the most common diseases in the aging process of the human body. With the increase of age, the incidence of arteriosclerosis among middle-aged and elderly people is higher. Usually, aortic sclerosis and coronary arteriosclerosis occur first, and then cerebral arteriosclerosis occurs. hardening. If combined with high blood pressure, it is a risk factor for cerebral hemorrhage and cerebral thrombosis. According to medical research and investigation results, arteriosclerosis is the main cause of death in the elderly, and cardiovascular disease and cerebrovascular disease account for the first number of deaths, which are mainly caused by arteriosclerosis. Therefore, people get enlightenment from it: in order to reduce hemiplegia caused by apoplexy, the occurrence and development of arteriosclerosis must be prevented first, and the prevention of arteriosclerosis must start with reducing the total amount of blood lipids. Hyperlipidemia is also a risk factor for atherosclerotic heart disease. How to reduce hyperlipidemia can not only prevent stroke and hemiplegia, but also prolong life. Researchers have also studied and investigated, and hemiplegia is basically caused by two reasons: hypertension and arteriosclerosis. Among them, hypertension accounts for 80% of the incidence of hemiplegia, which is common in elderly patients. Hypertension, like a long-term chronic disease, often causes arteriosclerosis. The reason is that high blood pressure increases vascular tension, excessive tension in the arterial intima, rupture of elastic fibers, damage to the arterial intima, and affects the permeability and nutrients of blood vessels. delivery. High blood pressure can easily cause capillary rupture and arterial intima hemorrhage to form blood clots. In this way, due to the change of blood components, the cholesterol and triglycerides in the blood will increase, resulting in arteriosclerosis.

When suffering from hypertension, due to the thickening of the blood vessel wall and the interaction of lipids in the blood, there will be lipid deposition on the arterial wall, which will thicken, harden, become brittle, and lose elasticity. When the blood pressure suddenly rises When the arterial wall with existing disease can no longer bear it, the arterial wall ruptures and bleeds. When it occurs in a blood vessel in the brain it is called a cerebral hemorrhage. Without proper treatment, hypertensive patients are most prone to stroke and even hemiplegia.

As for high blood pressure, cerebral arteriosclerosis, abnormal blood rheology, dizziness, dizziness, and numbness of the thumb and index finger, how to understand these phenomena has become the goal of research and development in the medical field. Traditional Chinese medicine points out that obese people who often eat high-fat food are prone to hemiplegia. Qi deficiency and blood stasis are the important causes of hemiplegia, and some people think that it is caused by deficiency of qi and blood and blockage of meridians.

However, for the treatment of the above-mentioned diseases, the synthesis and preparation process of the medicament is very complicated, and there are often side effects in the medication, which will damage the gastrointestinal tract and liver as a result, so it is not ideal.

In view of this, the present inventor, on the basis of personal experience of hemiplegia, on the basis of the stroke caused by cerebral thrombosis, under the situation of life-threatening surgical removal, dabbled in ancient Chinese records and agreed with the higher security sticking method, according to traditional Chinese medicine, The theory of traditional Chinese medicine has been developed for middle-aged and elderly people to prevent stroke, heart thrombosis, lower cholesterol, dredge meridians (treat muscle and bone pain), eliminate toxins in the body, relieve labor and troubles, eradicate youth beans, Hong Kong's feet, women's menstrual irregularities, and numbness of hands and feet. , Frozen shoulder and other diseases of sticking powder composition.

In fact, the above-mentioned various diseases are all external and internal, which are caused by qi deficiency and blood stasis, and blockage of meridians, which makes viruses in the body gather and induces the generation of lesions. If the Tie Shi powder composition can be absorbed into the human body through the dermis without oral administration to deliver the drug effect, it can avoid the damage to the gastrointestinal tract and liver caused by the oral drug. Way.

This kind of external application treatment method, in which the sticking powder composition is blended into a paste and applied to a specific part of the human skin or the corresponding part of the receptor, can be said to be an important method for treating common diseases, chronic diseases, frequently-occurring diseases, and refractory diseases. method.

The above-mentioned sticking therapy can be applied on the upper disease, upper application on the lower disease, external application on the internal disease, and application of medicine on the diseased part. The ancients have long used sticking therapy to treat diseases and achieve curative effect. For example, Li Shizhen mentioned in the book "Compendium of Materia Medica" that "the raw aconite is ground into powder and green onion juice is used as mud, and sticking to Yongquan point is used to treat nasal sinusitis", which shows that sticking therapy is a long-standing therapy.

As for why the treatment site is selected on the specific site of the human skin or the corresponding site of the receptor. Generally, as the well-known and popular foot massage method of Father Wu, because there are corresponding acupoints on the soles of the feet corresponding to the receptors of the human body, although it has a certain curative effect, it is a physical massage method after all, and it only has a short-term relief effect. Not really curative.

However, the present invention uses the raw materials of traditional Chinese medicines and grinds them into powder for application. On the site, the sticking powder composition can penetrate the pores of the skin and be easily absorbed into the human body from the dermis, because 90% of the dermis is a connective tissue rich in blood vessels, which can be responsible for the delivery of drugs. The number of hair follicles on the Baihui acupoint on the treatment site is large and the permeability is high, which is very conducive to the absorption of the drug, and the cuticle of the hands and feet is thin, which is the site where the drug is easily absorbed. Therefore, the sticking powder composition can pass through the acupuncture points, fur, Meridians work, so as to achieve the purpose of treating diseases by dredging the meridians, activating collaterals, promoting qi and blood circulation. This is because the acupuncture points are distributed on the meridian, which is an important part of the human tissue structure. It is a unique system that communicates the inside and outside. , stimulating the acupoints to play the role of conducting meridians, so that the drug can fully exert its pharmacological effects. It can be seen from the above that if the sticking powder composition is used, it can be absorbed into the human body through the dermis without oral administration (or injection), and the delivery of the drug effect can avoid the damage to the gastrointestinal tract and liver of the oral drug. It can be said that the method is simple, safe and reliable. A feasible method with definite curative effect is an important method for treating common diseases, chronic diseases, frequently-occurring diseases, and refractory diseases.

As for how to prepare the Tie Shi San composition, the inventor studied Chinese medicine books and various Baishi prescription books, sorted out and screened on the basis of traditional Chinese medicines that have the functions of dredging the meridian and activating collaterals, strengthening the body and eliminating pathogenic factors, promoting qi and blood circulation to remove blood stasis. .

As for the traditional Chinese medicines that can dredge the meridians, strengthen the body and eliminate pathogenic factors, promote qi, activate blood and remove blood stasis, after screening, there are: peach kernel: its medicinal effect is to remove blood stasis and break blood, moisten dryness and smooth intestines, and is suitable for blood stasis.

Dysmenorrhea, amenorrhea, bruises; glutinous rice: it can detoxify and suppurate, and it is ground into powder, which is sticky and suitable for blending

into a paste; White Pepper: It has the effect of lowering the Qi and reducing inflammation, and is also used for citing scriptures. It can be combined with peach kernels,

Saffron has the function of dispelling blood stasis and breaking blood, and expels toxins; almond: it can lower Qi and promote phlegm, and can sweat.

 The effect of citing scriptures, combined with peach kernels and (West) safflower to break blood stasis and eliminate

Swelling with guidance, lowering qi and promoting phlegm, and turning poisonous gas into sweat to expel

Effects in vitro.

Among the above-mentioned ingredients, peach kernels, glutinous rice, and pepper have been found in "Mainland Folk Remedies for Serious Illnesses-Volume 2" edited by Gao Yunwang (Wang'an Publishing House, first edition in Taiwan: July 15, 1992, page 4) In the composition of the antihypertensive cake folk prescription in the book, it only has the function of dredging the blood and achieves a partial effect of lowering blood pressure. However, the dosage of each component is not recorded in detail. In addition to achieving the function of blood circulation, the inventor has painstakingly studied the formula of traditional Chinese medicine, sorted out and selected the raw materials of traditional Chinese medicine with detoxification function, and used other substances such as vinegar and acetate to soften the cuticle of the sole of the foot. , egg white, raw land, Chuanqi, wine, water or vinegar, etc. can be used to mix the sticking powder composition into a paste for sticking softener.

In addition to the components of the above Tie Shi San compositions that achieve the function of dredging blood, as long as the original medicinal materials with detoxification function can be used as Tie Shi San The components of the composition include, for example, saffron, rhubarb, salvia miltiorrhiza, Chuanxiong, wood turtle, achyranthes bidentata, and tragacanth. If it is added to the patch powder composition of the present invention, its consumption accounts for about 20-60% by weight of the total amount of the composition. As for the effects of different medicinal flavors, take tragacanth as an example. Its pharmacological effects have the functions of invigorating qi and raising yang, strengthening the surface and antiperspirant, diuresis, reducing swelling, and draining pus. It also has dual regulating effects on blood pressure. When blood pressure is high, it can lower blood pressure. When it is low, it can increase blood pressure. It is often used to promote blood circulation without harming righteousness, balance yin and yang, and harmonize qi and blood. It has a deep effect on promoting blood circulation and removing blood stasis.

The pharmacological effects of other ingredients are described as follows: (West) safflower: its functions are mainly used to relieve blood stasis, reduce swelling, relieve pain, and generate new blood;

The circulatory disorder has obvious promoting effect.

The components with detoxification function that can be generally used in the sticking powder composition of the present invention are suitable as ingredients for priming medicines, which can include American ginseng, licorice, honeysuckle, centipede, etc., wherein licorice is used in various prescriptions for nourishing qi and detoxification. It is often reused in Chinese medicine and has obvious drug effects, so it can also be blended in the plaster powder composition of the present invention. Honeysuckle can dissipate heat and detoxify, treat paralysis, gangrene and scabies, nourish blood and quench thirst, and it is also an available medicinal material. The above total consumption for serving as priming medicine accounts for about 30% by weight of the plaster powder composition. In addition, about 1-10% by weight of licorice can be added, so that the total amount of the priming medicine accounts for about 40% by weight of the plaster powder composition. The dosage of each herbal flavor can be added or subtracted depending on the needs of its pharmacological effects.

One of the purposes of the sticking powder composition of the present invention is to provide one or more traditional Chinese medicines selected from the material group consisting of peach kernels, southern almonds, white pepper, glutinous rice and white yarrow, which have the function of opening blood passages. 30% to 45% by weight of the original medicinal material, and one selected from the material group composed of centipede, saffron, honeysuckle, rhubarb, bezoar, licorice powder, salvia miltiorrhiza, Chuanxiong, wood turtle, achyranthes bidentata, and tragacanth with detoxification function 55% to 70% by weight of one or more kinds of traditional Chinese medicine raw materials, and one or more substances selected from the group consisting of vinegar and acetates with the function of softening the cuticle, Shengdi and Chuanqi, After grinding, if necessary, adding a thickening agent, and mixing thoroughly with vinegar, water or wine, it is a powder-type composition for application prepared from raw materials of traditional Chinese medicines, which can be used for application.

As mentioned above, the antihypertensive biscuit formula (including white pepper, almond, glutinous rice, peach kernel, and gardenia) on the fourth page of "Mainland Folk Remedies for Serious Illnesses - Volume 2" only has the effect of dredging the blood, and can reduce the blood pressure. Part of the curative effect of blood pressure, plus "this folk prescription is ground into fine powder, mixed with egg white into a cake shape, applied on the center of the foot, wrapped with gauze, and removed after getting up the next day. If the sole of the foot is blue, it means Lower blood pressure. Continuous use for five days is a course of treatment" (from the second half of the same page). In this way, it was found that this folk prescription only has the effect of dredging the blood and lowering blood pressure. However, after the application, the soles (plates) of the feet turn purple, which is unsightly, especially when women wear high heels. In addition, after removing the dressing and cleaning it, the soles of the feet appeared blue and purple. Although the above-mentioned folk prescriptions exerted their medicinal effects to draw toxins out of the body, the skin on the soles of the soles of the feet where the prescription of the antihypertensive cake was applied accumulated and turned purple. . However, a few small red blisters appear on the skin of the feet (this phenomenon is similar to the blisters between the toes of the human body). These small blisters are endotoxins, which are transported to the peripheral nerves of the toes through the blood. If the peripheral nerves can function, the toxin will turn into blisters and be discharged from the soles of the feet. If it fails to function, it can be caused by the toxins in the body of patients with chronic diseases such as diabetes and hypertension without being excreted through this channel. Symptoms of illness.

In view of this, the plaster powder composition of the present invention is not only selected to use the original Chinese medicinal materials with the function of dredging the blood, but also selected the original Chinese medicinal materials with the function of detoxification, and the function of softening the cuticle of the soles of the feet (commonly known as foot cocoons). One or more substances selected from the substance group consisting of vinegar and acetates, raw land, and Chuanqi, are thoroughly mixed, and thickeners are added if necessary, and vinegar, water or wine are used to make a paste. The dosage form of the sticking powder composition prepared from the raw materials of traditional Chinese medicines can be used for sticking.

In order to completely eliminate toxins in the body, the inventor studied the books of traditional Chinese medicine and found that there are centipede, saffron, honeysuckle, rhubarb, bezoar, licorice powder, salvia miltiorrhiza, Chuanxiong, ground turtle, achyranthes bidentata, tragacanth, etc., which have the functions of detoxification. Functional raw medicinal materials, in addition, choose softeners that have the function of softening the cuticle, such as vinegar and acetate, Shengdi and Chuanqi, vinegar, wine and water, etc., when used together to soften the cuticle, it can promote sticking powder The composition has the function of clearing the blood, and can remove toxins in the body smoothly, achieving a double effect, and the sticking powder composition of the present invention does not need to be as troublesome as the aforementioned antihypertensive cake prescription, which must be made into a cake shape with egg whites. , and there is no unsightly concern of blue-purple formation on the feet after application.

As for the sticking powder composition of the present invention, except for the effects of the aforementioned three ingredients such as peach kernel, glutinous rice and pepper, there is no further explanation on the dosage. Here, the present invention further explains the composition and dosage of Tie Shi San, which has the functions of blood circulation, detoxification and softening of the tissue layer, as follows: peach kernel: the effect is as described above. Its dosage is about 10-30% by weight,

Below 10% by weight, the effect on dispelling blood stasis and breaking blood is less significant; (West) Huahong: Its function is mainly for breaking blood stasis, disinfection, pain relief, and generating new blood.

Its dosage is about 3 to 15% by weight; glutinous rice: the effect is as described above. The dosage is about 0.4 to 1.2% by weight; white) pepper: the effect is as mentioned above. The dosage is about 0.4～1.2

% by weight; southern almond: the effect is as described above. When its dosage is combined with cinnamon sticks and white pepper,

 account for about 10 to 30% by weight of the plaster powder composition in full amount,

When used in combination with peach kernels, it accounts for more than about 25% by weight of the composition

superior. Vinegar and acetates: Usually vinegar is mainly edible vinegar. its used to soften the feet

  The stratum corneum (cocoon) smoothes the detoxification in the body and increases

  Speed through the meridians. Vinegar is mainly composed of acetic acid, usually

in liquid form. In order to make the patch suitable for the present invention combine

Substances, salts of acetic acid can also be used, such as sodium acetate,

  Potassium acetate, calcium acetate, etc. The acetates are powdered

    Like solids, which can be mixed into powder compositions for application, in

    When in use, use water or other liquids (such as: wine)

    Mix thoroughly to form a paste, ready for application; thickener: before using the above-mentioned antihypertensive biscuit formula, mix it with egg whites to form a cake

It can only be applied, and it is troublesome to use. Application of the present invention

The bulk composition can be added in advance about 0.5 to 2.

0% by weight tackifier dry powder. Suitable tackifiers,

  Can be listed: sodium polyacrylate, polyacrylic acid, polyethylene

Enol, polyvinyl. Synthesis of pyrrolidones with high water solubility

Molecules, natural high content such as gum arabic, starch, protein, gelatin, etc.

Molecule, methylcellulose, hydroxypropylcellulose, carboxymethylcellulose

Sodium vitamins, alginic acid, sodium alginate, ammonium alginate, etc.; wine: rice wine is generally used for plaster powder compositions, while other wines are regarded as

 It can also be applied if necessary. Its function can not only be used for blending, but also can accelerate the speed of medicine.

Effective dredging of the meridians (removing blood stasis and dredging the veins).

The sticking powder composition of the present invention can be formulated into a sticking powder, so that it can be absorbed into the human body through the dermis without taking it orally, so as to deliver the drug effect and avoid the damage to the gastrointestinal tract and liver caused by the oral medicine. It can be said to be a method. Simple, safe and reliable, with definite curative effect, it should be a feasible method. It mainly contains 30-45% by weight of one or more raw materials of traditional Chinese medicine selected from the group consisting of peach kernels, southern almonds, white pepper, glutinous rice and white yarrow, and selected from the One or more raw materials of traditional Chinese medicine selected from the material group consisting of centipede, saffron, honeysuckle, rhubarb, bezoar, licorice powder, salvia miltiorrhiza, Chuanxiong, ground turtle, achyranthes bidentata, and Huangzhu 55-70 weight %, with one or more substances selected from the group consisting of vinegar and acetates with the function of softening the cuticle, Chuanqi and habitat, 0.5 to 4.0% by weight (the total amount of the former two) Grind it, add thickening agent if necessary, mix thoroughly with vinegar, water or wine to form a paste for sticking.

In addition, the plaster powder composition of the present invention can be pre-formulated into a wet cloth, that is, the plaster powder composition of the present invention can form a transdermal therapeutic system for skin application, and this system includes an impermeable active substance (this active substance is the composition that can be used for sticking after mixing the powder composition for application), a pressure-sensitive adhesive storage layer (such as the wet cloth base described later) and an optional The optional removable protective layer, comprising a woven or non-woven fabric is attached to a prefabricated self-adhesive wet cloth base, the patch powder composition of the present invention is mixed into a paste to form the active substance attachment It is added to the fabric or non-woven fabric, and then the base and the active substance attachment are covered with a covering layer. This is formulated into a so-called wet cloth.

The wet cloth agent will be described below. The wet cloth agent is composed of synthetic water-soluble polymers selected from sodium polyacrylate, polyacrylic acid, polyvinyl alcohol, polyvinyl pyrrolidone, polyethylene oxide, polyvinyl acrylate, etc., gum arabic, starch, gelatin, etc. One or more thickeners selected from the group consisting of natural substances, methylcellulose, hydroxypropylcellulose, alginic acid, sodium alginate, ammonium alginate and sodium carboxymethylcellulose , one or more wetting agents selected from the group consisting of urea, glycerin, propylene glycol, butylene glycol, and glucitol, selected from kaolin, zinc oxide, talc, titanium dioxide, bentonite, and epoxy One or more fillers selected from the group of substances consisting of resins, consisting of calcium, magnesium and aluminum salts of citric acid, tartaric acid, maleic acid, maleic anhydride and succinic acid One or more organic acid salts selected from the substance group, water, and one or more dissolution aids selected from the substance group consisting of propylene carbonate and diisopropyl adipate and selected from One or more adhesion-imparting agents selected from the group consisting of rosin resin, ester gum, polybutene and polyacrylate, and selected from the group consisting of chloroaniline maleate, glycyrrhizin and adrenal cortex One or more than one contact dermatitis preventive agent selected from the composition of the substance group, and if necessary, add the selected from salicylic acid, methyl salicylate, salicylic acid diol, 1-menth alcohol, camphor, nonanoic acid Vanillamide, Daphnetol, Capsaicin and Peppermint Oil are formulated with one or more additives selected from the material group to form a wet cloth base, and the paste powder composition of the present invention is thoroughly mixed into a paste to form an active substance attached The attachment is added to the wet cloth base and pre-added to the fabric or non-woven fabric, and then the base and the active substance attachment are coated with a covering layer, which is the wet cloth of the present invention.

In addition, the patch powder composition of the present invention can also be formulated into a plaster. The base for the plaster is derived from known polymer bases (for example: acrylate-based compositions of copolymers of methacrylates, acrylonitrile, vinyl acetate, vinyl propionate, etc., and vinyl monomers, Silicone resin, polyisoprene rubber, polyisobutylene rubber, natural rubber, acrylic rubber, styrene-butadiene-styrene block copolymer, styrene-isoprene-styrene block copolymer Body, etc.), oil or higher fatty acid (such as: almond oil, olive oil, camellia oil, peanut oil, oleic acid oil, paraffin, polybutene, etc.), adhesion imparting agent (such as: rosin, rosin modified maleic acid, hydrogenated abietate, etc.) and contact dermatitis preventive agents are appropriately selected, and if necessary, such as camphor, 1-menth alcohol, revanillol, nonanoic vanillyl amide, capsaicin and peppermint are added Other additives such as oil are formulated into the base for plaster, and the patch powder composition of the present invention is mixed in the base to obtain a uniform mixture, and this mixture is spread and coated on the support in a general way (for example: for Stretchable or non-stretchable base cloth, non-woven fabric or paper, etc.), on which it can be pasted appropriately from polyethylene, polypropylene, polyvinyl chloride, polyester, polyvinylidene chloride , Silicone processed paper, etc.

The plaster powder composition of the present invention is suitable for reducing blood pressure of high blood pressure and preventing stroke, and can double the curative effect of the ingredients in the composition. Cerebral thrombosis makes the patient's blood rheology abnormal, which has been confirmed by experts and scholars. Usually, it can be detected by abnormalities in inspection items such as increased whole blood viscosity, increased hemoglobin, prolonged electrophoresis time of platelets and hemoglobin, increased fibrinogen, increased platelet aggregation and adhesion. The patient's blood is abnormal in hemorheological behavior, showing "thick, sticky, coagulated, and aggregated" blood clots. Of course, the sticking powder composition of the present invention can be divided into preventive treatment group and control group to carry out hemorheology change comparison to patient before and after preventive treatment (check items can be whole blood viscosity, hemoglobin aggregation index, hemoglobin pressure as mentioned above) volume, fibrinogen, platelet aggregation rate, platelet adhesion rate). Usually, the preventive treatment group can reduce blood viscosity and hemoglobin aggregation state, and reduce plasma fibrinogen and platelet aggregation rate and adhesion rate. And those who use the pasting powder composition of the present invention can drop blood from their fingers in water before and after use, and find that the blood coagulates in the water and immediately diffuses when it drops into the water after use, and it can also be easily confirmed that the blood is sticky. The consistency has been reduced. In addition, the callus (cuticle) of the foot becomes thinner, smoother and finer. Obviously, it is also known that toxins in the body are discharged from the sole of the foot. The sticking powder composition of the present invention is also applicable to women with irregular menstruation (dysmenorrhea), which is confirmed by the phenomenon that a large amount of jet-black stasis is excreted from the body.

The following examples are used to further describe the powder composition for application of the present invention in detail, but this is not intended to limit the scope of the present invention. The weight % mentioned in the following examples is based on the total amount of the patch powder composition.

Example 1

Take 16.0% by weight of peach kernel, 0.8% by weight of glutinous rice, 1.0% by weight of white pepper, 12.0% by weight of southern almond, 1.2% by weight of Achillea, 15.0% by weight of centipede, 10.0% by weight of saffron, 5.0% by weight of honeysuckle, and 6.0% by weight of rhubarb %, 5.0% by weight of licorice powder, 4.5% by weight of salvia miltiorrhiza, 5.0% by weight of Chuanxiong, 7.0% by weight of wood turtle, 3.5% by weight of Achyranthes bidentata, 6.0% by weight of tragacanth, and 2.0% by weight of sodium acetate. Protein powder 3.0% by weight (based on the aforementioned full amount). Then get the gained powder mixture 100g, slowly add water therein and mix thoroughly into a paste, apply to the soles of the feet, with support (such as can be selected from stretchable or non-stretchable base cloth, non-woven fabric, non-woven paper, Polyethylene, polypropylene, polyvinyl chloride, polyvinylidene chloride, processed paper, etc.) and leave it overnight (about 8 to 10 hours), remove the cleaning patch and apply it loosely, it is found that the cuticle of the sole of the foot is softened and can be scraped off, and The skin of the soles of the feet is delicate and smooth, and the blood pressure has decreased compared with before application.

Example 2

Take 14.0% by weight of peach kernel, 1.0% by weight of glutinous rice, 1.0% by weight of white pepper, 18.0% by weight of southern almond, 1.0% by weight of Achillea, 20.0% by weight of centipede, 15.0% by weight of saffron, 3.0% by weight of licorice powder, and 8.0% by weight of salvia miltiorrhiza % by weight, Rhizoma Chuanxiong 6.0% by weight, Eucalyptus 2.0% by weight, Achyranthes bidentata 3.0% by weight, Tragacanth 4.0% by weight and Chuanqi 4.0% by weight are rolled into powder. Then take 100g of the obtained powder mixture, slowly add edible vinegar to it, mix thoroughly to form a paste, apply it on the sole of the foot, cover it with a support and leave it overnight (about 8 to 10 hours), remove it, wash it, apply it loosely, and find the sole of the foot The cuticle softens and can be scraped off, and the skin on the soles of the feet is fine and smooth, and women have menstrual pain before menstruation. After the application, the black menstrual blood will be discharged to make menstruation smooth.

Example 3

Take 17.0% by weight of peach kernel, 0.4% by weight of glutinous rice, 1.0% by weight of white pepper, 25.0% by weight of southern almond, 0.6% by weight of Achillea, 8.0% by weight of centipede, 7.0% by weight of saffron, 9.0% by weight of rhubarb, and 0.5% by weight of bezoar %, 7.5% by weight of licorice powder, 8.0% by weight of salvia miltiorrhiza, 3.0% by weight of Rhizoma Chuanxiong, 5.0% by weight of wood turtle, 6.0% by weight of Achyranthes bidentata and 2.0% by weight of yellow root, which are rolled into powder, and 2.0% by weight of sodium alginate is added thereto % (based on the aforementioned full amount). Then take 100g of the obtained powder mixture, add 10.0ml of edible vinegar and rice wine to it, mix thoroughly to form a paste, apply it on the sole of the foot, cover it with a support and leave it overnight (about 8 to 10 hours), remove it, wash it and apply it loosely. The cuticle of the sole of the foot is softened and can be cleaned, and the skin of the sole of the foot is fine and smooth. For those suffering from frozen shoulder, there will be no soreness after application.

Example 4

Get the powder 10-50% by weight (based on the total amount of the wet cloth preparation) of any sticking powder composition of the above-mentioned embodiment and mix and dissolve with 0.5-8% by weight of isopropyl adipate dissolution aid to form a uniform shape, and then 5-20% by weight of sodium carboxymethyl cellulose tackifier is dispersed and dissolved in 5-40% by weight of glycerin wetting agent and 10-80% by weight of water, and 10% by weight of zinc oxide and talc filler are added to make a uniform mixture . The mixture is spread and coated on the support in the usual way, and the covering can be peeled off on it to obtain a wet cloth preparation, which can be used for sticking the soles of the feet.

Claims (5)

1. A powder composition for patching, comprising: The first class of raw Chinese medicinal materials, which contains 16% peach kernel, 12% southern almond, 1% white pepper, 0.8% glutinous rice and 1.2% Baiqi; The second type of raw materials of traditional Chinese medicine, which contains 15% of centipede, 10% of safflower, 5% of honeysuckle, 6% of rhubarb, 5% of licorice powder, 4.5% of salvia miltiorrhiza, 5% of Chuanxiong, 7% of soft-shelled turtle, 3.5% of Achyranthes bidentata and astragalus 6%; and 2% acetates. 2. A powder composition for patching, comprising: The first class of raw medicinal materials of traditional Chinese medicine, which contains 14% of peach kernel, 18% of almond, 1% of white pepper, 1% of glutinous rice and 1% of Baiqi; The second type of raw Chinese medicinal materials, which contains 20% of centipede, 15% of safflower, 3% of licorice powder, 8% of salvia miltiorrhiza, 6% of chuanxiong, 2% of ground turtle, 3% of Achyranthes bidentata and 4% of astragalus; and 4% Panax notoginseng. 3. A powder composition for patching, comprising: The first class of raw Chinese medicinal materials, which contains 17% peach kernel, 25% southern almond, 1% white pepper, 0.4% glutinous rice and 0.6% Baiqi; The second class of raw materials of traditional Chinese medicine, which contains 8% centipede, 7% safflower, 9% rhubarb, 0.5% bezoar, 7.5% licorice powder, 8% salvia miltiorrhiza, 3% rhizoma chuanxiong, 5% soft-shelled turtle, 6% achyranthes bidentata and astragalus 2%; and 10ml of edible vinegar. 4. The application of the patch powder composition according to any one of claims 1 to 3 in the preparation of a medicament for improving the patient's blood circulation and applied on the patient's skin. 5. A wet cloth preparation, which contains the patch composition according to any one of claims 1 to 3 and a wet cloth base.