CN108992074A - microdialysis probe implanted device - Google Patents
microdialysis probe implanted device Download PDFInfo
- Publication number
- CN108992074A CN108992074A CN201810880445.1A CN201810880445A CN108992074A CN 108992074 A CN108992074 A CN 108992074A CN 201810880445 A CN201810880445 A CN 201810880445A CN 108992074 A CN108992074 A CN 108992074A
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- China
- Prior art keywords
- probe
- puncture
- fixation member
- implanted device
- fixing piece
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150022—Source of blood for capillary blood or interstitial fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150732—Needle holders, for instance for holding the needle by the hub, used for example with double-ended needle and pre-evacuated tube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150977—Arrays of piercing elements for simultaneous piercing
- A61B5/150984—Microneedles or microblades
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The present invention provides a kind of microdialysis probe implanted device.The microdialysis probe implanted device, including probe fixation member, puncture booster parts, the probe fixation member is removably connect with the puncture booster parts, the probe fixation member includes fixed plate body, probe fixing piece, the probe fixing piece includes steel needle, the probe fixing piece passes through the steel needle when in use and installs fixed microdialysis probe, probe fixing piece position is adjustably connect with the fixed plate body, when being punctured, the puncture booster parts can force the probe fixation member to move towards puncture position.Implanted device according to the present invention, microdialysis probe can be oppressed by means of puncturing booster parts, to realize the accurate puncture implantation of microdialysis probe, and the firmly problem of non-uniform for manually forcing implantation can be prevented, the working efficiency for improving implantation work requires the operative skill of medical staff lower.
Description
Technical field
The invention belongs to technical field of medical instrument, and in particular to a kind of microdialysis probe implanted device.
Background technique
With the development of the society, Microdialysis Technique is as a kind of relatively advanced micro biochemistry sampling, detection technique
It is widely applied.Its cardinal principle is that microdialysis probe is made with the semi-permeable membrane with certain molecular cut off, when micro-
After analysis probe is implanted in destination organization, the small molecule in extracellular fluid diffuses to filling by semi-permeable membrane under concentration gradient driving
In fluid injection, then the efflux with certain flow rate is collected, necessary detection is carried out using other precision instruments later, divides
Analysis.
And take the premise of technique is then how to enter in destination organization Fine needle biopsy namely how to be implanted into target
In tissue, at present frequently with mode be medical staff or scientific research personnel by manually carrying out puncture implantation, but this people
There is non-uniform problem of exerting oneself in the mode of work operation, it reduce the accuracys of the working efficiency and puncture that puncture implantation, separately
Outside, this improves requirement of the operator for the operative skill level of implantation work to a certain extent.
Summary of the invention
It therefore, can be by means of the technical problem to be solved in the present invention is that providing a kind of microdialysis probe implanted device
It punctures booster parts to oppress microdialysis probe, to realize the accurate puncture implantation of microdialysis probe, and can prevent
The firmly problem of non-uniform for manually forcing implantation, improves the working efficiency of implantation work, the operative skill of medical staff is wanted
Ask lower.
To solve the above-mentioned problems, the present invention provides a kind of microdialysis probe implanted device, including probe fixation member, wears
Booster parts are pierced, the probe fixation member is removably connect with the puncture booster parts, described to wear when being punctured
Thorn booster parts can force the probe fixation member to move towards puncture position.
Preferably, the probe fixation member is removably connect with the puncture booster parts, the probe fixed part
Part includes fixed plate body, probe fixing piece, and the probe fixing piece includes steel needle, and the probe fixing piece passes through institute when in use
It states steel needle and fixed microdialysis probe is installed, probe fixing piece position adjustably connect with the fixed plate body, carrying out
When puncture, the puncture booster parts can force the probe fixation member to move towards puncture position.
Preferably, there is lock hole on the fixed plate body, the booster parts that puncture have the locking hook that can be risen and fallen,
When the probe fixation member and the puncture booster parts assemble, the locking hook can be flush-mounted in the lock hole
It is interior, so that the probe fixation member is connected as one with the puncture booster parts.
Preferably, the fixed plate body has the first conduit parallel to each other, the second conduit with Z-shaped slot described in Z-shaped slot,
Distance of first conduit apart from the steel needle is less than distance of second conduit apart from the steel needle, and the steel needle is fixed
Part can slide in the Z-shaped slot, and can be locked in first conduit, and/or, described can be locked in
In two conduits.
Preferably, the probe fixing piece is equipped with Double-face adhesive scholar away from the side of the fixed plate body.
Preferably, the puncture booster parts include pull rod, sleeve, spring, mounting blocks, and the mounting blocks are equipped with the drawing
One end of bar, the spring is in the mounting blocks and sleeve is deposited between the spaces in the axial direction, and the pull rod, sleeve, bullet
Spring coaxial package, when the pull rod and the sleeve generate puncture on direction when moving toward one another, the spring can be pressed
Contracting.
Preferably, the sleeve has the ring-type extended toward its inside convex away from probe fixation member one end
Platform, the pull rod is equipped with hook far from one end of the probe fixation member, when the pull rod is backwards to the probe fixation member
When movement, the hook can be connected on the annular boss, so that the spring is maintained at compressive state；The pull rod also has
There is the button that can bounce pressure, when the button is depressed, it is convex in the ring-type that the button can be such that the hook is detached from
Platform.
Preferably, the sleeve has the extension board extended towards probe fixation member side, the extension board
Plate face and puncture direction have the first included angle A, A≤45 °.
Preferably, the microdialysis probe implanted device further includes that tail is stifled, and the tail is stifled to be set to the sleeve away from institute
State probe fixation member one end.
Preferably, the sleeve is equipped with card-bit part, and/or, the tail is blocked equipped with card-bit part.
A kind of microdialysis probe implanted device provided by the invention, the probe fixation member are used for microdialysis probe
It is fixed, is connected as one the microdialysis probe with the probe fixation member, the puncture booster parts are used for
Force the probe fixation member that the steel needle that carry microdialysis probe is driven to move along direction is punctured, when specifically used,
Microdialysis probe is put into the steel needle of the probe fixation member, thus realize the accurate puncture implantation of microdialysis probe, and
It can prevent the firmly problem of non-uniform for manually forcing implantation, improve the working efficiency of implantation work；In addition, due to the spy
Needle fixing piece is adjustably connect with the fixed plate body position, and so as to realize after implantation, the probe is consolidated
Determine part to adjust to the position far from implantation point, only retains microdialysis probe film layer at this time subcutaneous, this is conducive to as subsequent behaviour
Make to provide necessary operating space, under certain conditions, due to the probe fixation member, puncture between booster parts can
Detaching structure can directly remove the probe fixation member, puncture booster parts in the case where not needing aforementioned device
It all can or even directly abandon processing；Using aforementioned device, general medical staff be can be operated, the operation for medical staff
Skill requirement is lower.
Detailed description of the invention
Fig. 1 is the schematic perspective view of the microdialysis probe implanted device of the embodiment of the present invention；
Fig. 2 is the schematic diagram of the section structure of Fig. 1；
Fig. 3 is the schematic diagram of the section structure at another visual angle of Fig. 1.
Appended drawing reference indicates are as follows:
1, probe fixation member；11, fixed plate body；12, probe fixing piece；13, Z-shaped slot；14, lock hole；21, locking card
It hooks；22, pull rod；23, sleeve；24, spring；25, button；251, reset spring；26, card-bit part；27, extension board；28, it installs
Block；29, tail is stifled；3, steel needle；31, microdialysis probe；4, annular boss；5, hook.
Specific embodiment
In conjunction with referring to shown in Fig. 1 to 3, according to an embodiment of the invention, a kind of microdialysis probe implanted device is provided, including
Probe fixation member 1 punctures booster parts, and the probe fixation member 1 is removably connect with the puncture booster parts, institute
Stating probe fixation member 1 includes fixed plate body 11, probe fixing piece 12, and the probe fixing piece 12 includes steel needle 3, the probe
Fixing piece 12 installs fixed microdialysis probe 31 by the steel needle 3 when in use, and 12 position of probe fixing piece is adjustable
Ground is connect with the fixed plate body 11, and when being punctured, the puncture booster parts can force the probe fixation member 1
It is moved towards puncture position.Probe fixation member 1 described in the technical solution is used for through the steel needle 3 to microdialysis probe
31 are fixed, and are connected as one the microdialysis probe 31 with the probe fixation member 1, the puncture booster parts
It, will be micro- when specifically used for forcing the probe fixation member 1 that microdialysis probe 31 is driven to move along direction is punctured
Analysis probe 31 is put into the steel needle 3, to realize the accurate puncture implantation of probe, and can prevent the use for manually forcing implantation
Power problem of non-uniform improves the working efficiency of implantation work；In addition, due to the probe fixing piece 12 and the fixed plate body
11 positions adjustably connect, and so as to realize after implantation, the probe fixing piece 12 is adjusted to far from implantation
The position of point only retains microdialysis probe film layer subcutaneous at this time, this is conducive to provide necessary operation sky for subsequent operation
Between, under certain conditions, due to the detachable structure between the probe fixation member 1, puncture booster parts, do not needing
In the case where aforementioned device, the probe fixation member 1 can be directly removed, booster parts are punctured or even directly abandons processing
?；Using the microdialysis probe implanted device of the technical program, general medical staff be can be operated, for the behaviour of medical staff
It is lower to make skill requirement.
As the probe fixation member 1, a kind of specific embodiment of puncture booster parts connection, it is preferable that described
There is lock hole 14, the booster parts that puncture have the locking hook 21 that can be risen and fallen, when the probe is solid on fixed plate body 11
When determining component 1 and puncture booster parts assembling, the locking hook 21 can be in the lock hole 14, so that institute
Probe fixation member 1 is stated to be connected as one with the puncture booster parts.The technical solution is carried out by the way of buckle, simply
It is convenient, further increase the efficiency of implantation work.
Preferably, the fixed plate body 11 has Z-shaped slot 13, and the Z-shaped slot 13 has the first conduit parallel to each other, the
Two conduits, distance of first conduit apart from the steel needle 3 are less than distance of second conduit apart from the steel needle 3, institute
Stating probe fixing piece 12 can slide in the Z-shaped slot 13, and can be locked in first conduit, and/or, it can
It is locked in second conduit.Specifically, latched position can be realized by the way of clamping, it is further, described
For probe fixing piece 12 when sliding into second conduit, the cell wall of second conduit is equipped with elastic-buckle structure, will
The probe fixing piece 12 is adjusted to horizontal position by vertical position, is then fixed the probe by the elastic-buckle structure
Part 12 is locked in horizontal position, it is further preferable that the upper surface of the probe fixing piece 12 in horizontal position is lower than the fixation
The upper surface of plate body 11 namely the probe fixing piece 12 of horizontal position can be hidden in the second conduit of the Z-shaped slot.
The probe fixing piece 12 is equipped with Double-face adhesive scholar away from the side of the fixed plate body 11, and double-sided adhesive is to be attached to fixation
The back side of plate body 11, be the movement for preventing it；112 relative movement is that have the fixation of buckle.Further, described double
The bonding area of face paste scholar is not more than 5cm2, this aspect can set convenient for the miniaturization of the microdialysis probe implanted device
On the other hand meter can then guarantee comfort of the sufferer after microdialysis probe implantation, specifically, when the bonding area is excessive
When, the skin contact area of adhesive surface and sufferer implant site is excessive, this can stimulate the skin of sufferer to disease in a way
Trouble brings discomfort.The glue of adhesive bandage formula can be selected in the alite paste of the Double-face adhesive scholar, preferably stingless to skin in terms of material
Sharp medical material, such as non-woven fabrics, plastics and rubber, wherein plastics can be PE, PTFE, PES, PU, medical grade PVC etc.；
Rubber can be silicon rubber etc..The Double-face adhesive scholar can be fixed on the one of the fixed plate body 11 by hot pressing or gluing
Side.
As a kind of specific embodiment for puncturing booster parts, it is preferable that the puncture booster parts include
Pull rod 22, sleeve 23, spring 24, mounting blocks 28, the mounting blocks 28 are equipped with one end of the pull rod 22, and the spring 24 is in
The mounting blocks 28 are deposited between the spaces in the axial direction with sleeve 23, and the pull rod 22, sleeve 23,24 coaxial package of spring,
When the pull rod 22 and the sleeve 23 generate puncture on direction when moving toward one another, the spring 24 can be compressed.This
When, the steel needle 3 is carried out to force implantation by the compression prestress of the spring 24, further ensures the uniform of force
Property, further, by selecting the spring 24 of different-stiffness that can enhance the stress adaptability of different implantation objects.
A kind of stable specific embodiment of compressive state is realized as the guarantee spring 24, it is preferable that the sleeve
23 have the annular boss 4 extended toward its inside away from described 1 one end of probe fixation member, and the pull rod 22 is far from described
One end of probe fixation member 1 is equipped with hook 5, when the pull rod 22 is moved backwards to the probe fixation member 1, the hook
5 can be connected on the annular boss 4, so that the spring 24 is maintained at compressive state；The pull rod 22 also has and can bounce
The button 25 of pressure, when the button 25 is depressed, the button 25 can be such that the hook 5 is detached from the annular boss
4, as a kind of specific embodiment of the button 25, for example, being arranged in the button 25 towards the side of the pull rod 22
Reset spring 251, the reset spring 251 are then sleeved on the guide post that the button 25 has, and axial the two of reset spring 251
End is connected between the button 25 and the inner wall of the sleeve 23, and the button 25 is flexibly connected with the sleeve 23, is answered
It is realized by the reset spring 251 position.
Certainly the implanted device is necessary artificial auxiliary there is still a need for carrying out during carrying out specific implant procedure
It helps, for example, needing operator to hold the force pull rod 22 forces compression of spring 24 etc., puncture angle selection is also advantageous
In the efficiency for promoting implantation work, in order to improve the angle accuracy for puncturing implantation, while it can also make puncture angle more adduction
Reason, it is preferable that the sleeve 23 has the extension board 27 extended towards 1 side of probe fixation member, the extension board 27
Plate face and puncture direction there is the first included angle A, A≤45 ° such as can be 45 °, and more preferably can choose is 28 °, at this
Puncture angle, which is in a more appropriate range, to be guaranteed to the restriction of A, implant procedure band will not be given since A value is too small
It is inconvenient to come.
The microdialysis probe implanted device further includes tail stifled 29, and the tail stifled 29 is set to the sleeve 23 away from described
1 one end of probe fixation member, to prevent pull rod 22 and/or spring 24 in the sleeve 23 from deviating from.
As described above, the steel needle 3 needs to match use with the microdialysis probe 31 in the specific use process, it is described
Microdialysis probe 31 is often longer, when in use, if not carrying out fixation appropriate to it, will seriously affect and punctures implantation work
Working efficiency, it is therefore preferred that the sleeve 23 is equipped with card-bit part 26, and/or, the tail stifled 29 is equipped with card-bit part 26,
The card-bit part 26 can be made of having reeded sheet body, and the microdialysis probe 31 can be in the groove.
3 model of steel needle is preferably smaller than No. 22 steel needles, and length is preferably smaller than 10mm, such as can be 5mm, preferably small
In 3mm.
Steel needle 3 by any bio-compatibility and can have the material of mechanical strength to be made, such as stainless steel, titanium and titanium close
Golden, silicon and its compound, tungsten alloy, plastics, ceramics etc.；As a kind of mode for more saving cost, commercially available part can be used such as
Hypodermic needle, Kumetrix ' s silicon micropin etc..
Probe fixation member 1, puncture booster parts can be made of the material that can be used for Medical Devices, such as plastics, rubber
Glue, metal, ceramics etc., wherein plastics can be PE, PP, POM, PTFE, PES, PSU, PEEK, PC, PU and medical grade PVC etc.；
Rubber can be silicon rubber etc.；Metal can be stainless steel, titanium, titanium alloy, aluminium, aluminium alloy etc..
The microdialysis probe implanted device can be machined or the method for mold manufacture is manufactured.
Those skilled in the art will readily recognize that above-mentioned each advantageous manner can be free under the premise of not conflicting
Ground combination, superposition.
The above is merely preferred embodiments of the present invention, be not intended to limit the invention, it is all in spirit of the invention and
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within principle.Above only
It is the preferred embodiment of the present invention, it is noted that for those skilled in the art, do not departing from this hair
Under the premise of bright technical principle, several improvements and modifications can also be made, these improvements and modifications also should be regarded as guarantor of the invention
Protect range.
Claims (10)
1. a kind of microdialysis probe implanted device, which is characterized in that including probe fixation member (1), booster parts are punctured, it is described
Probe fixation member (1) is removably connect with the puncture booster parts, when being punctured, the puncture booster parts energy
The probe fixation member (1) is enough forced to move towards puncture position.
2. implanted device according to claim 1, which is characterized in that the probe fixation member (1) includes fixed plate body
(11), probe fixing piece (12), the probe fixing piece (12) include steel needle (3), and the probe fixing piece (12) is when in use
Installed fixed microdialysis probe (31) by the steel needle (3), probe fixing piece (12) position adjustably with it is described solid
Fixed board body (11) connection.
3. implanted device according to claim 2, which is characterized in that have lock hole on the fixed plate body (11)
(14), the booster parts that puncture have the locking hook (21) that can be risen and fallen, when the probe fixation member (1) and the puncture
When booster parts assemble, the locking hook (21) can be in the lock hole (14), so that the probe fixed part
Part (1) is connected as one with the puncture booster parts.
4. implanted device according to claim 3, which is characterized in that the fixed plate body (11) has Z-shaped slot (13), institute
Z-shaped slot (13) are stated with the first conduit parallel to each other, the second conduit, distance of first conduit apart from the steel needle (3)
Distance less than second conduit apart from the steel needle (3), the probe fixing piece (12) can be in the Z-shaped slots (13)
Sliding, and can be locked in first conduit, and/or, it can be locked in second conduit.
5. implanted device according to claim 4, which is characterized in that the probe fixing piece (12) deviates from the fixed plate
The side of body (11) is equipped with Double-face adhesive scholar.
6. implanted device according to claim 5, which is characterized in that the puncture booster parts include pull rod (22), set
Cylinder (23), spring (24), mounting blocks (28), the mounting blocks (28) are equipped with the one end of the pull rod (22), the spring (24)
It is deposited between the spaces in the axial direction in the mounting blocks (28) and sleeve (23), and the pull rod (22), sleeve (23), spring
(24) coaxial package, when the pull rod (22) and the sleeve (23) generate puncture on direction when moving toward one another, the bullet
Spring (24) can be compressed.
7. implanted device according to claim 6, which is characterized in that the sleeve (23) deviates from the probe fixation member
(1) one end has the annular boss (4) extended toward its inside, and the pull rod (22) is far from the probe fixation member (1)
One end be equipped with hook (5), when the pull rod (22) backwards to the probe fixation member (1) move when, the hook (5) can block
It is connected on the annular boss (4), so that the spring (24) is maintained at compressive state；The pull rod (22) also has and can bounce
The button (25) of pressure, when the button (25) is depressed, the button (25) can be such that the hook (5) are detached from described
Annular boss (4).
8. implanted device according to claim 7, which is characterized in that the sleeve (23) has fixes towards the probe
The extension board (27) that component (1) side extends, the plate face of the extension board (27) and punctures direction and has the first included angle A, and A≤
45°。
9. implanted device according to claim 8, which is characterized in that further include that tail blocks up (29), the tail blocks up (29) setting
Deviate from described probe fixation member (1) one end in the sleeve (23).
10. the implanted device according to any one of claim 6 to 8, which is characterized in that the sleeve (23) is equipped with card
Position part (26), and/or, the tail blocks up (29) and is equipped with card-bit part (26).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810880445.1A CN108992074A (en) | 2018-08-04 | 2018-08-04 | microdialysis probe implanted device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810880445.1A CN108992074A (en) | 2018-08-04 | 2018-08-04 | microdialysis probe implanted device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108992074A true CN108992074A (en) | 2018-12-14 |
Family
ID=64594740
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810880445.1A Pending CN108992074A (en) | 2018-08-04 | 2018-08-04 | microdialysis probe implanted device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108992074A (en) |
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Application publication date: 20181214 |