CN108938522B - Makeup removing lotion containing PEG-12 monolaurate and preparation method thereof - Google Patents
Makeup removing lotion containing PEG-12 monolaurate and preparation method thereof Download PDFInfo
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 30
- UIVPNOBLHXUKDX-UHFFFAOYSA-N 3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate Chemical compound CC(C)(C)CC(C)CCOC(=O)CC(C)CC(C)(C)C UIVPNOBLHXUKDX-UHFFFAOYSA-N 0.000 claims abstract description 25
- XJNUECKWDBNFJV-UHFFFAOYSA-N hexadecyl 2-ethylhexanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)C(CC)CCCC XJNUECKWDBNFJV-UHFFFAOYSA-N 0.000 claims abstract description 25
- 229940100554 isononyl isononanoate Drugs 0.000 claims abstract description 25
- 239000006210 lotion Substances 0.000 claims abstract description 22
- 102100022442 Calmin Human genes 0.000 claims abstract description 20
- 101710185175 Calmin Proteins 0.000 claims abstract description 20
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 19
- 239000003906 humectant Substances 0.000 claims abstract description 14
- 239000003755 preservative agent Substances 0.000 claims abstract description 13
- 230000002335 preservative effect Effects 0.000 claims abstract description 13
- 239000002562 thickening agent Substances 0.000 claims abstract description 10
- 239000000049 pigment Substances 0.000 claims abstract description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 46
- 239000008267 milk Substances 0.000 claims description 26
- 210000004080 milk Anatomy 0.000 claims description 26
- 235000013336 milk Nutrition 0.000 claims description 26
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 19
- 235000011187 glycerol Nutrition 0.000 claims description 19
- 239000006071 cream Substances 0.000 claims description 18
- MXOAEAUPQDYUQM-QMMMGPOBSA-N (S)-chlorphenesin Chemical compound OC[C@H](O)COC1=CC=C(Cl)C=C1 MXOAEAUPQDYUQM-QMMMGPOBSA-N 0.000 claims description 17
- CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical group CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 claims description 17
- 229960003993 chlorphenesin Drugs 0.000 claims description 17
- 238000010438 heat treatment Methods 0.000 claims description 14
- 239000000230 xanthan gum Substances 0.000 claims description 14
- 229920001285 xanthan gum Polymers 0.000 claims description 14
- 229940082509 xanthan gum Drugs 0.000 claims description 14
- 235000010493 xanthan gum Nutrition 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 6
- DWHIUNMOTRUVPG-UHFFFAOYSA-N 2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Chemical compound CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCO DWHIUNMOTRUVPG-UHFFFAOYSA-N 0.000 claims description 5
- 229910019142 PO4 Inorganic materials 0.000 claims description 5
- 229940031674 laureth-7 Drugs 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 5
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 5
- 239000010452 phosphate Substances 0.000 claims description 5
- 229920002401 polyacrylamide Polymers 0.000 claims description 5
- 238000000265 homogenisation Methods 0.000 claims description 4
- 238000001816 cooling Methods 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 230000002421 anti-septic effect Effects 0.000 claims description 2
- -1 PEG-12 monolaurate Chemical compound 0.000 claims 1
- 238000004321 preservation Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 16
- 230000003020 moisturizing effect Effects 0.000 abstract description 7
- 238000002360 preparation method Methods 0.000 abstract description 6
- 206010020751 Hypersensitivity Diseases 0.000 abstract description 4
- 206010061218 Inflammation Diseases 0.000 abstract description 4
- 208000026935 allergic disease Diseases 0.000 abstract description 4
- 230000007815 allergy Effects 0.000 abstract description 4
- 230000004054 inflammatory process Effects 0.000 abstract description 4
- 230000003467 diminishing effect Effects 0.000 abstract description 3
- 210000003491 skin Anatomy 0.000 description 13
- 229940062000 polyglyceryl-2 triisostearate Drugs 0.000 description 10
- 239000002994 raw material Substances 0.000 description 9
- 238000012360 testing method Methods 0.000 description 7
- 230000003247 decreasing effect Effects 0.000 description 4
- 206010013786 Dry skin Diseases 0.000 description 3
- 230000003266 anti-allergic effect Effects 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 230000037336 dry skin Effects 0.000 description 3
- 208000003251 Pruritus Diseases 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000001804 emulsifying effect Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 1
- 241000218691 Cupressaceae Species 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 201000009053 Neurodermatitis Diseases 0.000 description 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 description 1
- 230000001387 anti-histamine Effects 0.000 description 1
- 239000000739 antihistaminic agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000005587 bubbling Effects 0.000 description 1
- 238000003889 chemical engineering Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000011056 performance test Methods 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- NKMFPXBSJDHRKV-UHFFFAOYSA-N propan-2-yl 7-methyloctanoate Chemical compound CC(C)CCCCCC(=O)OC(C)C NKMFPXBSJDHRKV-UHFFFAOYSA-N 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000013112 stability test Methods 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8158—Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/14—Preparations for removing make-up
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
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- A61Q19/00—Preparations for care of the skin
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Abstract
The invention discloses a makeup removing lotion containing PEG-12 monolaurate and a preparation method thereof. The makeup removing lotion consists of the following components: 13-17% of PEG-12 monolaurate, 4-6% of isononyl isononanoate, 2-4% of cetyl ethyl hexanoate, 1-3% of polyglycerol-2 triisostearate, 0.2-0.4% of thickening agent, 10-12% of humectant, 2-3% of emulsifier, 0.1-0.4% of pH regulator, 0.5-1.5% of oat kernel extract, 0.5-1.5% of bradypeptide Calmin, 0-proper amount of preservative, 0-proper amount of essence, 0-proper amount of pigment, the balance of water and the pH of 6.5-7.0. By optimizing the formula, the obtained makeup removing lotion has the advantages of good makeup removing effect, allergy resistance, inflammation diminishing, excellent moisturizing performance, good smearing feeling and the like, and also has the advantage of good stability.
Description
Technical Field
The invention belongs to the field of daily cosmetics, and particularly relates to makeup removing lotion containing PEG-12 monolaurate and a preparation method thereof.
Background
People need to use various foundation make-up products due to social life and beauty, most foundation make-up products contain a large amount of powder and pigment, and in order to keep skin clean, pores are not blocked by various powder and oil stains, skin burden is relieved, and special make-up removing products are needed to be completely clean.
The makeup remover can clean makeup completely without over cleaning to dry skin, and the makeup remover is produced along with the use of the makeup remover. The makeup removing cream can be used for assisting in removing makeup, and is suitable for removing makeup in daily life and has a good moisturizing effect on skin because the makeup removing cream is moderate in water-oil balance, oily components of the makeup removing cream can wash dirt away, and water-based components can keep skin moist. The makeup removing cream has the characteristics of easy smearing, easy cleaning after use and the like, so the development of the makeup removing cream with various effects has wide market prospect.
Disclosure of Invention
The invention aims to provide the makeup removing milk containing the PEG-12 monolaurate. The cleansing cream has the characteristics of good makeup removing capability, allergy prevention, antibiosis and antiphlogosis, itching relieving, skin moistening, moisture retention and convenience in use.
The invention also aims to provide a preparation method of the makeup removing cream.
The purpose of the invention is realized by the following technical scheme: the makeup removing lotion containing PEG-12 monolaurate comprises the following components in percentage by mass: 13-17% of PEG-12 monolaurate, 4-6% of isononyl isononanoate, 2-4% of cetyl ethyl hexanoate, 1-3% of polyglycerol-2 triisostearate, 0.2-0.4% of thickening agent, 10-12% of humectant, 2-3% of emulsifier, 0.1-0.4% of pH regulator, 0.5-1.5% of oat kernel extract, 0.5-1.5% of bradypeptide Calmin, 0-proper amount of preservative, 0-proper amount of essence, 0-proper amount of pigment, the balance of water and the pH of 6.5-7.0; preferably consists of the following components in percentage by mass: 15% of PEG-12 monolaurate, 5% of isononyl isononanoate, 3% of cetyl ethyl hexanoate, 1.5% of polyglycerol-2 triisostearate, 0.3% of thickening agent, 11% of humectant, 2.6% of emulsifier, a proper amount of pH regulator, 1% of oat kernel extract, 1% of soothing peptide Calmin, 0-proper amount of preservative, 0-proper amount of essence, 0-proper amount of pigment and the balance of water; the pH value is 6.5 to 7.0.
The proper amount refers to the state, industry and other relevant regulations.
The balance refers to the sum of water and other components which is 100 percent of the mass percentage.
The thickener is preferably xanthan gum.
The humectant is preferably one or two of glycerin and dipropylene glycol; more preferably glycerol and dipropylene glycol at a mass ratio of 8: 3, mixing the components to obtain the mixed humectant.
The emulsifier is preferably one or two of C20-22 alcohol phosphate/C20-22 alcohol (SENSANOV WR) and polyacrylamide/C13-14 isoparaffin/laureth-7 (SEPIGEL 305); more preferably C20-22 alcohol phosphate/C20-22 alcohol (SENSANOV WR) and polyacrylamide/C13-14 isoparaffin/laureth-7 (SEPIGEL 305) in a mass ratio of 1: 1.6 the obtained emulsifier.
The pH regulator is preferably aminomethyl propanol.
The content of the aminomethyl propanol in the makeup removing milk is 0.1-0.4% by mass; more preferably 0.18%.
The essence is preferably FH318022 pink charming essence.
The content of the FH318022 pink charming essence in the makeup removing milk is 0.2-0.4% by mass; more preferably 0.3% by mass.
The preservative is preferably one or two of chlorphenesin and PE9010 liquid preservative.
The content of the chlorphenesin in the cleansing milk is 0.2-0.4% by mass; more preferably 0.3% by mass.
The content of the PE9010 liquid preservative in the makeup removing milk is 0.8-1.2% by mass; more preferably 1% by mass.
The preparation method of the makeup removing milk containing PEG-12 monolaurate comprises the following steps:
(1) mixing a part of emulsifier, PEG-12 monolaurate, isononyl isononanoate, cetyl ethyl hexanoate and polyglycerol-2 triisostearate, and heating at 80-90 ℃ until the mixture is completely melted to obtain an oil phase;
(2) mixing water, a thickening agent, a humectant and a pH regulator, and heating at 80-90 ℃ until the mixture is completely dissolved to obtain a water phase;
(3) adding the oil phase into the water phase, and homogenizing; adding the rest of the emulsifier, and homogenizing; preserving the heat at 80-90 ℃;
(4) cooling, adding antiseptic, essence, pigment, oat kernel extract and soothing peptide Calmin at proper temperature, and stirring to obtain makeup removing milk;
more preferably, the method comprises the following steps:
(1) adding SENSANOV WR, PEG-12 monolaurate, isononyl isononanoate, cetyl ethyl hexanoate and polyglycerol-2 triisostearate into an oil pan, and heating at 80-90 ℃ until the materials are completely melted to obtain an oil phase;
(2) mixing water, xanthan gum, dipropylene glycol, glycerol and aminomethyl propanol, and heating at 80-90 ℃ until the mixture is completely dissolved to obtain a water phase;
(3) adding the oil phase into the water phase, and homogenizing; adding SEPIGEL 305, and homogenizing; preserving the heat at 80-90 ℃;
(4) when the temperature is reduced to 70 ℃, chlorphenesin is added and the stirring is continued;
(5) adding PE9010, FH318022 pink charming essence, oat kernel extract and soothing peptide Calmin when the temperature is reduced to 40 ℃, and stirring uniformly to obtain makeup removing milk;
the contents of the substances are as follows: 13-17% of PEG-12 monolaurate, 4-6% of isononyl isononanoate, 2-4% of cetyl ethyl hexanoate, 1-3% of polyglycerol-2 triisostearate, 0.2-0.4% of thickening agent, 10-12% of humectant, 2-3% of emulsifier, 0.1-0.4% of pH regulator, 0.5-1.5% of oat kernel extract, 0.5-1.5% of bradypeptide Calmin, 0-proper amount of preservative, 0-proper amount of essence, 0-proper amount of pigment, the balance of water and the pH of 6.5-7.0.
The temperature of the heating in the step (1) is preferably 85 ℃.
The temperature of the heating in the step (2) is preferably 85 ℃.
The temperature of the heat-retaining in the step (3) is preferably 85 ℃.
The homogenization degree in the step (3) is to make the makeup removing milk into a uniform system, and the homogenization conditions are preferably as follows: homogenizing at 2500-3500 rpm for 3-5 min; more preferably, homogenization is carried out at a speed of 3000rpm for 4 minutes.
Compared with the prior art, the invention has the following beneficial effects:
(1) the invention uses PEG-12 monolaurate as a main makeup remover, contains oil and fat such as isononanoic acid isopropyl ester, cetyl ethyl hexanoate, polyglycerol-2 triisostearate and the like as auxiliary makeup removers, has good makeup removing capability, does not irritate the skin, causes itch and the like on the skin.
(2) The oat kernel extract and the soothing peptide Calmin have the effects of resisting allergy and diminishing inflammation, can inhibit neurodermatitis, have high-efficiency antihistamine activity and antioxidant activity, and can effectively prevent and slow down inflammation caused by various irritations.
(3) The combined emulsifier of SENSANOV WR and SEPIGEL 305 can not only keep the stability of the makeup removing cream, but also moisten the skin without dry skin.
(4) The makeup removing lotion contains high-content glycerin and dipropylene glycol humectant and has good skin moisturizing effect.
(5) By optimizing the formula, the cleansing milk obtained by the invention has the advantages of good cleansing effect, allergy resistance, inflammation diminishing, excellent moisturizing performance, good smearing feeling and the like, and also has the advantage of good stability.
Detailed Description
The present invention will be described in further detail with reference to examples, but the embodiments of the present invention are not limited thereto.
Example 1
The makeup removing lotion containing PEG-12 monolaurate comprises the following raw materials in percentage by mass: the balance of water, 15% PEG-12 monolaurate, 5% isononyl isononanoate, 3% cetyl ethylhexanoate, 1.5% polyglyceryl-2 triisostearate, 0.3% xanthan gum, 8% glycerin, 3% dipropylene glycol, 1% sensano v WR, 1.6% SEPIGEL 305, 0.18% aminomethyl propanol, 0.3% chlorphenesin and 1% PE9010, 0.3% FH318022 pink charm essence (guangzhou fenghao essence ltd), 1% oat kernel extract and 1% soothing peptide Calmin (guangzhou cypress chemical engineering limited).
The preparation steps are as follows:
(1) adding Sensanov WR, PEG-12 monolaurate, isononyl isononanoate, cetyl ethyl hexanoate, and polyglycerol-2 triisostearate into oil pan, stirring, and heating to 85 deg.C for complete melting.
(2) Adding water, xanthan gum, dipropylene glycol, glycerol and aminomethyl propanol into an emulsifying pot, heating to 85 deg.C, and stirring to dissolve.
(3) Pumping the materials in the oil pan into an emulsifying pan, homogenizing at 3000rpm under-0.03 MPa for 2 min, adding SEPIGEL 305, homogenizing at 3000rpm under-0.03 MPa for 2 min, stirring at 85 deg.C for 15 min, and cooling.
(4) When the temperature is reduced to 70 ℃, the chlorphenesin is added and the stirring is continued.
(5) PE9010, FH318022 pink charm essence, oat kernel extract and soothing peptide Calmin were added when the temperature was reduced to 40 ℃.
(6) And stirring and discharging after detection.
Example 2
The makeup removing lotion containing PEG-12 monolaurate comprises the following raw materials in percentage by mass: the balance of water, 15% PEG-12 monolaurate, 5% isononyl isononanoate, 3% cetyl ethylhexanoate, 1.5% polyglyceryl-2 triisostearate, 0.3% xanthan gum, 1% glycerin, 1% dipropylene glycol, 1% sensanol WR, 1.6% SEPIGEL 305, 0.18% aminomethyl propanol, 0.3% chlorphenesin and 1% PE9010, 0.3% FH318022 pink charm, 1% oat kernel extract and 1% bradypeptide Calmin.
The procedure was as in example 1.
Example 3
The makeup removing lotion containing PEG-12 monolaurate comprises the following raw materials in percentage by mass: the balance of water, 15% PEG-12 monolaurate, 3% isononyl isononanoate, 1% cetyl ethylhexanoate, 0.5% polyglyceryl-2 triisostearate, 0.3% xanthan gum, 8% glycerin, 3% dipropylene glycol, 1% sensanol WR, 1.6% SEPIGEL 305, 0.18% aminomethyl propanol, 0.3% chlorphenesin and 1% PE9010, 0.3% FH318022 pink charm, 1% oat kernel extract and 1% bradypeptide Calmin.
The procedure was as in example 1.
Example 4
The makeup removing lotion containing PEG-12 monolaurate comprises the following raw materials in percentage by mass: the balance of water, 15% PEG-12 monolaurate, 5% isononyl isononanoate, 3% cetyl ethylhexanoate, 1.5% polyglyceryl-2 triisostearate, 0.3% xanthan gum, 8% glycerin, 3% dipropylene glycol, 1% sensanol WR, 1.6% SEPIGEL 305, 0.18% aminomethyl propanol, 0.3% chlorphenesin and 1% PE9010, 0.3% FH318022 pink allure essence.
The procedure was as in example 1.
Example 5
The makeup removing lotion containing PEG-12 monolaurate comprises the following raw materials in percentage by mass: the balance of water, 10% PEG-12 monolaurate, 5% isononyl isononanoate, 3% cetyl ethylhexanoate, 1.5% polyglyceryl-2 triisostearate, 0.3% xanthan gum, 8% glycerin, 3% dipropylene glycol, 1% sensanol WR, 1.6% SEPIGEL 305, 0.18% aminomethyl propanol, 0.3% chlorphenesin and 1% PE9010, 0.3% FH318022 pink charm, 1% oat kernel extract and 1% bradypeptide Calmin.
The procedure was as in example 1.
Example 6
The makeup removing lotion containing PEG-12 monolaurate comprises the following raw materials in percentage by mass: the balance of water, 20% PEG-12 monolaurate, 5% isononyl isononanoate, 3% cetyl ethylhexanoate, 1.5% polyglyceryl-2 triisostearate, 0.3% xanthan gum, 8% glycerin, 3% dipropylene glycol, 1% sensanol WR, 1.6% SEPIGEL 305, 0.18% aminomethyl propanol, 0.3% chlorphenesin and 1% PE9010, 0.3% FH318022 pink charm, 1% oat kernel extract and 1% bradypeptide Calmin.
The procedure was as in example 1.
Example 7
The makeup removing lotion containing PEG-12 monolaurate comprises the following raw materials in percentage by mass: the balance of water, 15% PEG-12 monolaurate, 5% isononyl isononanoate, 4.5% polyglycerol-2 triisostearate, 0.3% xanthan gum, 8% glycerol, 3% dipropylene glycol, 1% sensanol WR, 1.6% SEPIGEL 305, 0.18% aminomethyl propanol, 0.3% chlorphenesin and 1% PE9010, 0.3% FH318022 pink charm, 1% oat kernel extract and 1% soothing peptide Calmin.
The procedure was as in example 1.
Example 8
The makeup removing lotion containing PEG-12 monolaurate comprises the following raw materials in percentage by mass: the balance of water, 15% PEG-12 monolaurate, 6.5% isononyl isononanoate, 3% cetyl ethylhexanoate, 0.3% xanthan gum, 8% glycerol, 3% dipropylene glycol, 1% sensanol WR, 1.6% SEPIGEL 305, 0.18% aminomethyl propanol, 0.3% chlorphenesin and 1% PE9010, 0.3% FH318022 pink charm essence, 1% oat kernel extract and 1% the soothing peptide Calmin.
The procedure was as in example 1.
Example 9
The makeup removing lotion containing PEG-12 monolaurate comprises the following raw materials in percentage by mass: the balance of water, 15% PEG-12 monolaurate, 5% isononyl isononanoate, 3% cetyl ethylhexanoate, 1.5% polyglyceryl-2 triisostearate, 0.3% xanthan gum, 8% glycerin, 3% dipropylene glycol, 2.6% sensanol WR, 0.18% aminomethyl propanol, 0.3% chlorphenesin and 1% PE9010, 0.3% FH318022 pink charm, 1% oat kernel extract and 1% soothing peptide Calmin.
The procedure was as in example 1.
Effects of the embodiment
Makeup removal performance test
(1) Test products: cleansing milk of examples 1 to 9
(2) The test population: sex: the number of women: age of 20 persons: 20-40 years old
Health condition: the subjects had no history of skin allergy and the skin was healthy.
(3) The test method comprises the following steps:
after makeup of the face of the subject, makeup removers of examples 1 to 9 were tried, respectively, and trial was continued for 7 days.
And (3) makeup removal effect test: about 2 g of the makeup removing cream is smeared on makeup removing cotton, then the makeup part on the face is wiped, and the makeup removing effect is good after 3-5 circles of makeup removing.
Anti-allergic and anti-inflammatory assay: 0.020-0.025 g of makeup removing cream is dripped into a patch lattice, the patch lattice is stuck to the arm for 48 hours, the mark is made and torn, and the patch lattice does not cause red swelling, peeling and bubbling within 24 hours, thereby having good anti-allergic and anti-inflammatory effects.
And (3) testing the moisturizing effect: the moisture content of the horny layer before and after the makeup removing cream was used was measured by a CK MPA580 moisture meter. Before and after the product is used, the moisture content of the stratum corneum in a test area is obviously different, which shows that the makeup removing lotion has good moisturizing effect.
Smearing effect: the makeup removing cream is easy to throw and wipe, the makeup removing cream body cannot flow, cannot form a lump and cannot be easily rubbed off, and meanwhile, the makeup removing cream is smoothly smeared on the skin and has no resistance.
(4) The efficacy test results, as shown in table 1:
TABLE 1
Example 5 the amount of PEG-12 monolaurate used was 10% less than that of example 1, the makeup removal effect was inferior to that of example 1, and the smearing feeling was relatively poor; example 6 the amount of PEG-12 monolaurate used was 20% greater than that of example 1, the makeup removal effect was substantially equivalent to that of example 1, and the feel of smearing was slightly inferior to that of example 1; example 3 isononyl isononanoate, cetyl ethylhexanoate and polyglyceryl-2 triisostearate were used in smaller amounts than in example 1, the makeup removal effect was inferior to that of example 1, and the smearing feeling was relatively poor; example 7 did not contain 3% of cetyl ethylhexanoate relative to example 1, but increased the amount of polyglyceryl-2 triisostearate (from 1.5% to 4.5% in example 1), and example 8 did not contain 1.5% of polyglyceryl-2 triisostearate relative to example 1, but increased the amount of isononyl isononanoate (from 5% to 6.5% in example 1), and the makeup removing effect and the feel of smearing of examples 7 and 8 were inferior to those of example 1. By combining the data analysis, the PEG-12 monolaurate is the main makeup remover, and too much or too little of the PEG-12 monolaurate has influence on the makeup removing effect and the smearing performance. Isononyl isononanoate, cetyl ethyl hexanoate, polyglycerol-2 triisostearate and other oil and fat are used as auxiliary makeup removing agents, the dosage of the oil and fat can also influence the makeup removing effect and the smearing feeling, and isononyl isononanoate, cetyl ethyl hexanoate and polyglycerol-2 triisostearate are organic matching combination for the invention.
In example 2, the content of glycerin and dipropylene glycol was decreased compared to example 1, the moisturizing effect was decreased, the anti-allergic and anti-inflammatory effects were also decreased, and the spreadability was also decreased. It can be seen that the content of glycerol and dipropylene glycol is also a relatively critical factor.
(5) Stability test results, as shown in table 2:
TABLE 2
And (3) hot and cold cycle testing: the heat resistance is 42 ℃ for one day, the cold resistance is-10 ℃ for one day, and the circulation is carried out.
Example 9 compared to example 1, the emulsifier used was sensanol WR only and the content was increased, and the emulsifier content was the same as that in example 1, but the makeup removing cream obtained in example 9 was unstable and could not be regarded as a good product.
(6) And (4) conclusion:
the results in tables 1 and 2 show that the makeup removing milk provided by the invention is an organic whole, and PEG-12 monolaurate, isononyl isononanoate, cetyl ethyl hexanoate, polyglycerol-2 triisostearate and other substances are jointly applied, so that the makeup removing milk is easy to spread, has good makeup removing capability and a certain skin care effect; the combined emulsifier of SENSANOV WR and SEPIGEL 305 can not only keep the stability of the makeup removing cream, but also moisten the skin without dry skin.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.
Claims (10)
1. The makeup removing lotion containing PEG-12 monolaurate is characterized by comprising the following components in percentage by mass: 13-17% of PEG-12 monolaurate, 4-6% of isononyl isononanoate, 2-4% of cetyl ethyl hexanoate, 1-3% of polyglycerol-2 triisostearate, 0.2-0.4% of thickening agent, 10-12% of humectant, 2-3% of emulsifier, 0.1-0.4% of pH regulator, 0.5-1.5% of oat kernel extract, 0.5-1.5% of bradypeptide Calmin, 0-proper amount of preservative, 0-proper amount of essence, 0-proper amount of pigment and the balance of water, wherein the pH is 6.5-7.0.
2. The makeup removing lotion containing PEG-12 monolaurate according to claim 1, characterized by consisting of the following components in percentage by mass: 15% of PEG-12 monolaurate, 5% of isononyl isononanoate, 3% of cetyl ethyl hexanoate, 1.5% of polyglycerol-2 triisostearate, 0.3% of thickening agent, 11% of humectant, 2.6% of emulsifier, a proper amount of pH regulator, 1% of oat kernel extract, 1% of soothing peptide Calmin, 0-proper amount of preservative, 0-proper amount of essence, 0-proper amount of pigment and the balance of water; the pH value is 6.5 to 7.0.
3. The makeup removing milk containing PEG-12 monolaurate according to claim 1 or 2, characterized in that: the thickening agent is xanthan gum;
the humectant is one or two of glycerin and dipropylene glycol;
the emulsifier is one or two of C20-22 alcohol phosphate/C20-22 alcohol and polyacrylamide/C13-14 isoparaffin/laureth-7.
4. The makeup removing cream containing PEG-12 monolaurate according to claim 3, characterized in that:
the humectant is prepared from glycerol and dipropylene glycol according to a mass ratio of 8: 3, mixing the obtained mixed humectant;
the emulsifier is C20-22 alcohol phosphate/C20-22 alcohol and polyacrylamide/C13-14 isoparaffin/laureth-7 according to the mass ratio of 1: 1.6 the obtained emulsifier.
5. The makeup removing milk containing PEG-12 monolaurate according to claim 1 or 2, characterized in that:
the pH regulator is aminomethyl propanol;
the essence is preferably FH318022 pink charming essence;
the preservative is one or two of chlorphenesin and PE9010 liquid preservative.
6. The makeup removing lotion containing PEG-12 monolaurate according to claim 5, characterized in that:
the content of the aminomethyl propanol in the makeup removing milk is 0.1-0.4% by mass;
the content of the FH318022 pink charming essence in the makeup removing milk is 0.2-0.4% by mass;
the content of the chlorphenesin in the cleansing milk is 0.2-0.4% by mass;
the content of the PE9010 liquid preservative in the makeup removing milk is 0.8-1.2% by mass.
7. The PEG-12 monolaurate-containing cleansing milk according to claim 6, characterized in that:
the content of the aminomethyl propanol in the makeup removing milk is 0.18 percent by mass;
the content of the FH318022 pink charming essence in the makeup removing milk is 0.3 percent by mass;
the content of the chlorphenesin in the cleansing milk is 0.3 percent by mass;
the content of the PE9010 liquid preservative in the makeup removing milk is 1% by mass.
8. The method for preparing the makeup removing cream containing PEG-12 monolaurate according to any one of claims 1 to 7, characterized by comprising the following steps:
(1) mixing a part of emulsifier, PEG-12 monolaurate, isononyl isononanoate, cetyl ethyl hexanoate and polyglycerol-2 triisostearate, and heating at 80-90 ℃ until the mixture is completely melted to obtain an oil phase;
(2) mixing water, a thickening agent, a humectant and a pH regulator, and heating at 80-90 ℃ until the mixture is completely dissolved to obtain a water phase;
(3) adding the oil phase into the water phase, and homogenizing; adding the rest of the emulsifier, and homogenizing; preserving the heat at 80-90 ℃;
(4) cooling, adding antiseptic, essence, pigment, oat kernel extract and soothing peptide Calmin at proper temperature, and stirring to obtain the cleansing milk.
9. The method for preparing a makeup removing lotion containing PEG-12 monolaurate according to claim 8, characterized by comprising the following steps:
(1) adding C20-22 alcohol phosphate/C20-22 alcohol, PEG-12 monolaurate, isononyl isononanoate, cetyl ethyl hexanoate and polyglycerol-2 triisostearate into an oil pan, and heating at 80-90 ℃ until the materials are completely melted to obtain an oil phase;
(2) mixing water, xanthan gum, dipropylene glycol, glycerol and aminomethyl propanol, and heating at 80-90 ℃ until the mixture is completely dissolved to obtain a water phase;
(3) adding the oil phase into the water phase, and homogenizing; adding polyacrylamide/C13-14 isoparaffin/laureth-7, and homogenizing; preserving the heat at 80-90 ℃;
(4) when the temperature is reduced to 70 ℃, chlorphenesin is added and the stirring is continued;
(5) and (3) when the temperature is reduced to 40 ℃, adding PE9010, FH318022 pink charming essence, oat kernel extract and soothing peptide Calmin, and uniformly stirring to obtain the makeup removing milk.
10. The method for preparing a makeup removing lotion containing PEG-12 monolaurate according to claim 8 or 9, characterized in that:
the heating temperature in the step (1) is 85 ℃;
the heating temperature in the step (2) is 85 ℃;
the temperature of the heat preservation in the step (3) is 85 ℃;
the homogenization conditions in the step (3) are as follows: homogenizing at 2500-3500 rpm for 3-5 min.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105687038A (en) * | 2016-03-05 | 2016-06-22 | 广州丹奇日用化工厂有限公司 | Skin-care makeup remover cream with skin surface lipid film repairing function and preparation method of skin-care makeup remover cream |
| CN105769662A (en) * | 2016-03-16 | 2016-07-20 | 广州丹奇日用化工厂有限公司 | Cleansing cream with anti-allergy function and method for preparing cleansing cream |
| CN106074256A (en) * | 2016-06-30 | 2016-11-09 | 广州众上投资控股集团有限公司 | A kind of solid spray makeup removing gel and preparation method and application |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105687038A (en) * | 2016-03-05 | 2016-06-22 | 广州丹奇日用化工厂有限公司 | Skin-care makeup remover cream with skin surface lipid film repairing function and preparation method of skin-care makeup remover cream |
| CN105769662A (en) * | 2016-03-16 | 2016-07-20 | 广州丹奇日用化工厂有限公司 | Cleansing cream with anti-allergy function and method for preparing cleansing cream |
| CN106074256A (en) * | 2016-06-30 | 2016-11-09 | 广州众上投资控股集团有限公司 | A kind of solid spray makeup removing gel and preparation method and application |
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