CN1088454A - Biyuanning medicine for treating nasosinusitis - Google Patents
Biyuanning medicine for treating nasosinusitis Download PDFInfo
- Publication number
- CN1088454A CN1088454A CN 93117300 CN93117300A CN1088454A CN 1088454 A CN1088454 A CN 1088454A CN 93117300 CN93117300 CN 93117300 CN 93117300 A CN93117300 A CN 93117300A CN 1088454 A CN1088454 A CN 1088454A
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- Prior art keywords
- herba
- medicine
- nasal
- biyuanning
- fructus forsythiae
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- 239000003814 drug Substances 0.000 title claims abstract description 21
- 241000218176 Corydalis Species 0.000 claims abstract description 9
- 241000628997 Flos Species 0.000 claims description 8
- 230000000694 effects Effects 0.000 abstract description 10
- 239000002775 capsule Substances 0.000 abstract description 7
- 230000001684 chronic effect Effects 0.000 abstract description 5
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 241000758794 Asarum Species 0.000 abstract 1
- 241001633683 Centipeda <firmicute> Species 0.000 abstract 1
- 244000035851 Chrysanthemum leucanthemum Species 0.000 abstract 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 abstract 1
- 241000555682 Forsythia x intermedia Species 0.000 abstract 1
- 241000112528 Ligusticum striatum Species 0.000 abstract 1
- 241000218378 Magnolia Species 0.000 abstract 1
- 244000246386 Mentha pulegium Species 0.000 abstract 1
- 235000016257 Mentha pulegium Nutrition 0.000 abstract 1
- 235000004357 Mentha x piperita Nutrition 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 235000001050 hortel pimenta Nutrition 0.000 abstract 1
- 238000007670 refining Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 201000009890 sinusitis Diseases 0.000 description 6
- 208000002193 Pain Diseases 0.000 description 5
- 230000003203 everyday effect Effects 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- 206010011732 Cyst Diseases 0.000 description 4
- 206010028748 Nasal obstruction Diseases 0.000 description 4
- 206010039101 Rhinorrhoea Diseases 0.000 description 4
- 208000031513 cyst Diseases 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 241000191940 Staphylococcus Species 0.000 description 3
- 241000194017 Streptococcus Species 0.000 description 3
- 239000000706 filtrate Substances 0.000 description 3
- 201000006916 frontal sinusitis Diseases 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 206010020880 Hypertrophy Diseases 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 208000036071 Rhinorrhea Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 208000027744 congestion Diseases 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 210000003928 nasal cavity Anatomy 0.000 description 2
- 208000010753 nasal discharge Diseases 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 206010039083 rhinitis Diseases 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 210000001944 turbinate Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000272814 Anser sp. Species 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 206010057315 Daydreaming Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 238000009837 dry grinding Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- DJGAAPFSPWAYTJ-UHFFFAOYSA-M metamizole sodium Chemical compound [Na+].O=C1C(N(CS([O-])(=O)=O)C)=C(C)N(C)N1C1=CC=CC=C1 DJGAAPFSPWAYTJ-UHFFFAOYSA-M 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 210000001331 nose Anatomy 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to a Chinese patent medicine Biyuanning capsule for treating acute and chronic nasosinusitis. It is prepared from magnolia flower, corydalis tuber, dahurian angelica root, centipeda, peppermint, asarum herb, forsythia fruit, wild chrysanthemum flower and ligusticum wallichii through disintegrating, extracting and refining. It has the advantages of high curative effect, no toxic side effect, no recurrence, etc.
Description
The present invention relates to a kind of nasal medicine for the treatment of sinusitis, belong to the Chinese patent medicine that pure Chinese medicine is made through refinement.
Sinusitis is the department of otorhinolaryngology common disease, and the traditional Chinese medical science is called " nasal sinusitis ", how to cause a disease with the infection of sinus cavities, doctor trained in Western medicine is many with anti-inflammatory treatment both at home and abroad at present, severe patient imposes the puncture flush operation, and effect is dissatisfied, normal easily recurrence, patient is difficult for accepting, " ' Biyanwan ' for treating rhinitis " that Chinese medicine has Guangzhou No.1 Chinese Pharmacy Factory to produce observed through clinical use, and its curative effect is lower, general about 75%, and curative effect is not consolidated.
The objective of the invention is to overcome above-mentioned weak point of the prior art, and provide a kind of sinusitis that is used for the treatment of, curative effect height, no side effects, the nasal medicine of non-relapse after healing.
The object of the present invention is achieved like this: the prescription of nasal medicine and compositing range (weight %) are Flos Magnoliae, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Herba Centipedae, each 2.19-5.79 of Herba Menthae, Herba Asari 1.12-1.96, Fructus Forsythiae, Herba Dendranthematis indici, Rhizoma Chuanxiong, each 17.34-21.99 of Radix Salviae Miltiorrhizae.Get Flos Magnoliae, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Herba Centipedae, Herba Menthae, Herba Asari ormal weight, it is standby that pulverize separately is crossed 80 mesh sieve mixings, gets Fructus Forsythiae, Herba Dendranthematis indici, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae ormal weight again, through pre-treatment, soaked 30-60 minute with ordinary water, heat and extract 5 times, each 40-60 minute, filter and remove residue, filtrate merges, cold put refiltered in 12 hours, concentrate, dry, pulverized 80 mesh sieves, with No. 0 capsule of above-mentioned standby former medicated powder mixing packing, every 0.3g.
Purpose of the present invention can also reach by following measure: the optimum formula of this medicine and compositing range (weight %) be Flos Magnoliae, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Herba Centipedae, Herba Menthae each 5.36, Herba Asari 1.79, Fructus Forsythiae, Herba Dendranthematis indici, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae each 17.86.
The present invention makes according to following mechanism: Fructus Forsythiae, Herba Dendranthematis indici have the effect of heat-clearing and toxic substances removing, and Flos Magnoliae, Herba Centipedae expelling pathogenic wind and restoring the functions of orifices in face are equipped with Radix Salviae Miltiorrhizae, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Rhizoma Chuanxiong, Herba Menthae, Herba Asari blood circulation promoting and blood stasis dispelling, the evacuation of pus pain relieving.Modern pharmacological research proves that Fructus Forsythiae, Herba Dendranthematis indici have inhibitory action to golden Portugal bacterium, streptococcus, staphylococcus, so can be sensible.
Cause a disease based on many infection with sinus cavities of sinusitis, clinical proof is with streptococcus, and staphy lococcus infection also has golden bacterium the infected of Portugal for seeing more, and symptom accompanies by distraction based on headache, nasal obstruction, rhinorrhea, symptoms such as hypomnesis.And the present invention is just at this susceptible reason and symptom, then with heat-clearing and toxic substances removing, expelling pathogenic wind and restoring the functions of orifices in face, blood circulation promoting and blood stasis dispelling, evacuation of pus pain relieving, suppress streptococcus, staphylococcus, golden Portugal bacterium and reach the purpose of treatment sinusitis.
The present invention has following advantage compared to existing technology:
1, evident in efficacy, according to 122 examples of treatment, by " diagnosis of traditional Chinese medical science otorhinolaryngology oral cavity department disease and criterion of therapeutical effect " statistics, clinical cure 75 examples, account for 61.47%, produce effects 25 examples account for 20.48%, effective 18 examples, account for 14.75%, invalid 4 examples account for 3.3%, total effective rate 96.75%.Its course of treatment is the longest 30 days, and is the shortest 5 days, average 11.1 days.Matched group 20 examples are to take ' Biyanwan ' for treating rhinitis, each 3 grams, every day three times is oral and add the Western medicine anti-inflammatory agent, the injection of penicillin injection 800,000 units, every day secondary, oral 1.0 grams of analgin tablet, every day three times is contrast, and matched group clinical cure 4 examples, account for 20%, produce effects 11 examples account for 55%, invalid 5 examples, account for 20%, total effective rate 75%.Handle two groups by statistics there were significant differences (P＜0.05) this explanation nasal medicine capsule and be better than matched group.
2, nontoxic, have no side effect.
3, non-relapse after healing.
Below in conjunction with embodiment in detail the present invention is described in detail.
With each flavor medicine total amount is that 1000g is an example:
Composition weight (g) weight (%)
Prescription 1 prescription 2 prescriptions 3 prescriptions 4 prescriptions 1 prescription 2 prescriptions 3 prescriptions 4
Flos Magnoliae 39.2 53.6 57.8 21.9 3.92 5.36 5.78 2.19
The Radix Angelicae Dahuricae 39.2 53.6 57.8 21.9 3.92 5.36 5.78 2.19
Rhizoma Corydalis 39.2 53.6 57.8 21.9 3.92 5.36 5.78 2.19
Goose not 39.2 53.6 57.8 21.9 3.92 5.36 5.78 2.19
The food grass
Herba Menthae 39.2 53.5 57.9 21.9 3.92 5.35 5.79 2.19
Herba Asari 19.6 17.9 17.3 11.2 1.96 1.79 1.73 1.12
Fructus Forsythiae 196.1 178.6 173.4 219.8 19.61 17.86 17.34 21.98
Herba Dendranthematis indici 196.1 178.6 173.4 219.8 19.61 17.86 17.34 21.98
Rhizoma Chuanxiong 196.1 178.5 173.4 219.8 19.61 17.85 17.34 21.98
Radix Salviae Miltiorrhizae 196.1 178.5 173.4 219.8 19.61 17.85 17.34 21.99
Its processing technology is to measure Flos Magnoliae by afore mentioned rules, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Herba Centipedae, Herba Menthae, Herba Asari removes impurity, pulverize separately, it is standby to cross 80 mesh sieve mixings, measure Fructus Forsythiae by afore mentioned rules again, Herba Dendranthematis indici, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae removes impurity, add ordinary water respectively and be as the criterion, soaked 50 minutes, heat and extract 5 times with the submergence Chinese herbal medicine, each 60 minutes, filter and remove residue then, gained filtrate merges, and cold putting refiltered in 12 hours, filtrate is condensed into clear paste at normal pressure, place drying below 60 ℃ then, 80 mesh sieves are crossed in the gained dry grinding, with above-mentioned standby former medicated powder mixing, in No. 0 capsule of packing, every 0.3g promptly makes the nasal medicine capsule.
Model case:
Example 1: Chen Hongmei, the woman, 11 years old, Ceng Yin is nasal obstruction, watery nasal discharge, a dull pain 2 years repeatedly, goes to Tangshan hospital to do CT examination, and return my examination in hospital: nasal cavity chronic congestion, swelling, middle nasal concha hypertrophy, the middle nasal meatus is narrow, the rheuminess thing.The X line is taken the photograph the sheet prompting, and frontal sinusitis and cyst 1 * 1.2cm on the right side examine to chronic upper right frontal sinusitis and cyst, take the nasal medicine capsule, every day three times, and each 6, to take medicine and checked in 10 days, the above-mentioned positive sign of clinical symptoms and nose disappears.The X report from a liner is accused inflammation and is disappeared, and cyst is before dwindled, so far not recurrence.
Example 2: infant Lang Ying is rich, the man, and 9 years old, nasal obstruction, watery nasal discharge, a dull pain were shown effect 1 year repeatedly, showed as giddy, and inappetence is easily tired, absent minded.Hypomnesis, rhinorrhea, nasal obstruction, a dull pain.Sign: the nasal cavity chronic congestion, swelling, the middle nasal concha hypertrophy, the middle nasal meatus is narrow, the rheuminess thing.The X report from a liner is accused bilateral hole transmucosal and thickened, and is fuzzy, muddiness, and increase in density, examining is that chronic (two) go up frontal sinusitis, takes nasal medicine cyst capsule every day three times, each 6, to take medicine 16 days, clinical symptoms and sign disappear.The X report from a liner is accused the disappearance of inflammation sign.
Claims (2)
1, a kind of nasal medicine is characterized in that its prescription and compositing range (weight %) are Flos Magnoliae, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Herba Centipedae, each 2.19-5.79 of Herba Menthae, Herba Asari 1.12-1.96, Fructus Forsythiae, Herba Dendranthematis indici, Rhizoma Chuanxiong, each 17.34-21.99 of Radix Salviae Miltiorrhizae.
2, nasal medicine according to claim 1, it is characterized in that optimum formula and compositing range (weight %) for Flos Magnoliae, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Herba Centipedae, Herba Menthae each 5.36, Herba Asari 1.79, Fructus Forsythiae, Herba Dendranthematis indici, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae each 17.86.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93117300 CN1088454A (en) | 1993-09-01 | 1993-09-01 | Biyuanning medicine for treating nasosinusitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93117300 CN1088454A (en) | 1993-09-01 | 1993-09-01 | Biyuanning medicine for treating nasosinusitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1088454A true CN1088454A (en) | 1994-06-29 |
Family
ID=4991958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 93117300 Pending CN1088454A (en) | 1993-09-01 | 1993-09-01 | Biyuanning medicine for treating nasosinusitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1088454A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055404C (en) * | 1995-12-01 | 2000-08-16 | 朱宝昌 | Nasosinusitis granule |
| CN1060081C (en) * | 1997-07-11 | 2001-01-03 | 云南省德宏傣族景颇族自治州民族医院 | Pure Chinese medicinal syrup preparation and its production tech. |
| CN1116895C (en) * | 1999-08-31 | 2003-08-06 | 李多存 | Medical capsule for treating nasosinusitis |
| CN1294931C (en) * | 2004-02-14 | 2007-01-17 | 刘强 | Compound collunarium oil and preparation method thereof |
| CN101332268B (en) * | 2007-06-29 | 2012-01-25 | 郑书信 | Medicine for treating rhinitis, sinusitis |
| CN105726635A (en) * | 2016-04-29 | 2016-07-06 | 孔庆晅 | Traditional Chinese medicine for treating nasosinusitis |
| CN108498669A (en) * | 2018-05-03 | 2018-09-07 | 李书文 | A kind of Chinese medicine for treating acute and chronic nasal sinusitis |
-
1993
- 1993-09-01 CN CN 93117300 patent/CN1088454A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055404C (en) * | 1995-12-01 | 2000-08-16 | 朱宝昌 | Nasosinusitis granule |
| CN1060081C (en) * | 1997-07-11 | 2001-01-03 | 云南省德宏傣族景颇族自治州民族医院 | Pure Chinese medicinal syrup preparation and its production tech. |
| CN1116895C (en) * | 1999-08-31 | 2003-08-06 | 李多存 | Medical capsule for treating nasosinusitis |
| CN1294931C (en) * | 2004-02-14 | 2007-01-17 | 刘强 | Compound collunarium oil and preparation method thereof |
| CN101332268B (en) * | 2007-06-29 | 2012-01-25 | 郑书信 | Medicine for treating rhinitis, sinusitis |
| CN105726635A (en) * | 2016-04-29 | 2016-07-06 | 孔庆晅 | Traditional Chinese medicine for treating nasosinusitis |
| CN108498669A (en) * | 2018-05-03 | 2018-09-07 | 李书文 | A kind of Chinese medicine for treating acute and chronic nasal sinusitis |
| CN108498669B (en) * | 2018-05-03 | 2020-11-13 | 李书文 | Traditional Chinese medicine for treating acute and chronic nasosinusitis |
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|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |