CN108828760A - One kind being used for cancer cell microscope automatic sampling apparatus - Google Patents
One kind being used for cancer cell microscope automatic sampling apparatus Download PDFInfo
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- CN108828760A CN108828760A CN201810921901.2A CN201810921901A CN108828760A CN 108828760 A CN108828760 A CN 108828760A CN 201810921901 A CN201810921901 A CN 201810921901A CN 108828760 A CN108828760 A CN 108828760A
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- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 20
- 201000011510 cancer Diseases 0.000 title claims abstract description 20
- 238000005070 sampling Methods 0.000 title claims abstract description 13
- 238000009434 installation Methods 0.000 claims description 19
- 125000006850 spacer group Chemical group 0.000 claims description 5
- 239000011521 glass Substances 0.000 abstract description 13
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- 238000000034 method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 230000000877 morphologic effect Effects 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 1
- 210000004324 lymphatic system Anatomy 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
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- G—PHYSICS
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- G02B21/26—Stages; Adjusting means therefor
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- G—PHYSICS
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- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
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Abstract
本发明公开了一种用于癌细胞显微镜自动进样装置,包括观察台、显微镜主体和载物台,所述显微镜主体固定安装在观察台上方的一侧,所述载物台固定安装在显微镜主体上,所述观察台上方远离显微镜主体的一侧固定安装有安装竖板,所述安装竖板靠近显微镜主体的一侧固定安装有液压机构,所述液压机构的输出端固定安装有伺服电机,所述伺服电机的驱动端固定连接有转轴,所述转轴远离伺服电机的一端固定连接有放置盘,所述放置盘远离转轴的一侧环形固定安装有四个夹持件,每个夹持件均由两个载物件组成。本发明减少了镜检人员更换载玻片的环节,从而一定程度上降低了镜检人员的工作强度,有利于镜检人员保持精力进行观察。
The invention discloses an automatic sampling device for cancer cell microscope, which comprises an observation table, a microscope main body and an object stage, the microscope main body is fixedly installed on one side above the observation table, and the object stage is fixedly installed on the microscope On the main body, a vertical plate is fixedly installed on the side away from the main body of the microscope above the observation platform, a hydraulic mechanism is fixedly installed on the side of the vertical plate close to the main body of the microscope, and a servo motor is fixedly installed on the output end of the hydraulic mechanism , the driving end of the servo motor is fixedly connected with a rotating shaft, and the end of the rotating shaft away from the servo motor is fixedly connected with a placement plate, and the side of the placing plate away from the rotating shaft is fixedly installed with four clamping parts in a ring, each clamping Each piece is composed of two loading objects. The present invention reduces the steps for microscopic examination personnel to replace glass slides, thereby reducing the work intensity of microscopic examination personnel to a certain extent, and is beneficial for microscopic examination personnel to maintain energy for observation.
Description
技术领域technical field
本发明涉及医疗临床检验技术领域,尤其涉及一种用于癌细胞显微镜自动进样装置。The invention relates to the technical field of medical clinical testing, in particular to an automatic sampling device for cancer cell microscopes.
背景技术Background technique
癌细胞是一种变异的细胞。是产生癌症的病源,癌细胞与正常细胞不同,有无限增殖、可转化和易转移三大特点,能够无限增殖并破坏正常的细胞组织。癌细胞除了分裂失控外(能进行多极分裂),还会局部侵入周遭正常组织甚至经由体内循环系统或淋巴系统转移到身体其他部分,癌细胞需要在医学显微镜下才能进行观察。A cancer cell is a mutated cell. It is the source of cancer. Cancer cells are different from normal cells. They have three characteristics: infinite proliferation, transformation and easy transfer. They can infinitely proliferate and destroy normal cell tissues. In addition to uncontrollable division of cancer cells (capable of multipolar division), cancer cells can also partially invade surrounding normal tissues and even transfer to other parts of the body through the internal circulatory system or lymphatic system. Cancer cells need to be observed under a medical microscope.
前医学实验室形态学显微镜镜检大多依赖人工操作,镜检人员不仅要长时间精神集中地观察显微镜,还要频繁更换载玻片,因此加大了镜检人员的工作强度,因此亟需设计一种用于癌细胞显微镜自动进样装置。Morphological microscope examinations in former medical laboratories mostly relied on manual operations. The microscopic examination personnel not only had to observe the microscope intensively for a long time, but also frequently changed slides, which increased the work intensity of the microscopic examination personnel. An automatic sampling device for cancer cell microscope.
发明内容Contents of the invention
本发明的目的是为了解决现有技术中存在的缺点,如:前医学实验室形态学显微镜镜检大多依赖人工操作,镜检人员不仅要长时间精神集中地观察显微镜,还要频繁更换载玻片,因此加大了镜检人员的工作强度。The purpose of the present invention is to solve the shortcomings existing in the prior art, such as: most of the former medical laboratory morphological microscope examinations rely on manual operation, and the microscopic examination personnel not only need to concentrate on observing the microscope for a long time, but also frequently change the carrier glass Therefore, the work intensity of the microscopic examination personnel is increased.
为了实现上述目的,本发明采用了如下技术方案:In order to achieve the above object, the present invention adopts the following technical solutions:
一种用于癌细胞显微镜自动进样装置,包括观察台、显微镜主体和载物台,所述显微镜主体固定安装在观察台上方的一侧,所述载物台固定安装在显微镜主体上,所述观察台上方远离显微镜主体的一侧固定安装有安装竖板,所述安装竖板靠近显微镜主体的一侧固定安装有液压机构,所述液压机构的输出端固定安装有伺服电机,所述伺服电机的驱动端固定连接有转轴,所述转轴远离伺服电机的一端固定连接有放置盘,所述放置盘远离转轴的一侧环形固定安装有四个夹持件,每个夹持件均由两个载物件组成,两个所述载物件相对的一侧均设有放置槽,每个所述载物件上均设有与放置槽连通的安装口,所述安装口内转动连接有螺杆,所述螺杆远离放置槽的一端固定安装有手柄,每个所述放置槽远离安装口一侧的内壁上均设有与螺杆转动连接的安装槽,每个所述螺杆上均设有第一外螺纹和第二外螺纹,所述第一外螺纹和第二外螺纹方向相反,每个所述螺杆位于放置槽内的部分均通过第一外螺纹螺纹连接有第一夹板,且通过第二外螺纹螺纹连接有第二夹板,所述第二夹板位于第一夹板的一侧。An automatic sampling device for cancer cell microscopes, comprising an observation table, a microscope main body and an object stage, the microscope body is fixedly installed on one side above the observation table, and the object table is fixedly installed on the microscope main body, the A vertical plate is fixedly installed on the side away from the main body of the microscope above the observation platform, and a hydraulic mechanism is fixedly installed on the side of the vertical plate close to the main body of the microscope, and a servo motor is fixedly installed on the output end of the hydraulic mechanism. The driving end of the motor is fixedly connected with a rotating shaft, and the end of the rotating shaft away from the servo motor is fixedly connected with a placement plate, and the side of the placing plate far away from the rotating shaft is fixedly installed with four clamping parts in a ring, and each clamping part consists of two It is composed of two loading objects, and the opposite sides of the two loading objects are provided with placement grooves, and each of the object loading objects is provided with an installation port communicating with the placement groove, and a screw rod is rotatably connected to the installation opening. The end of the screw rod away from the placement slot is fixedly equipped with a handle, and the inner wall of each placement slot away from the installation opening is provided with a mounting slot rotatably connected with the screw rod, and each of the screw rods is provided with a first external thread and The second external thread, the direction of the first external thread and the second external thread are opposite, and each part of the screw rod located in the placement groove is threaded with the first splint through the first external thread, and is threaded through the second external thread. A second splint is connected, and the second splint is located on one side of the first splint.
优选的,相邻的两个所述载物件之间通过两个限位杆固定连接,所述放置槽位于两个限位杆之间。Preferably, two adjacent object loading objects are fixedly connected by two limiting rods, and the placement groove is located between the two limiting rods.
优选的,每个所述第一夹板靠近第二夹板的一侧均固定安装有第一橡胶垫,每个所述第二夹板靠近第一夹板的一侧均固定安装有第二橡胶垫。Preferably, a first rubber pad is fixedly mounted on a side of each first splint close to the second splint, and a second rubber pad is fixedly mounted on a side of each second splint close to the first splint.
优选的,每个所述放置槽内均固定安装有导杆,每个所述第一夹板和每个第二夹板上均开设有用于滑动连接导杆的滑口。Preferably, a guide rod is fixedly installed in each of the placement slots, and each of the first splints and each second splint is provided with a sliding opening for slidingly connecting the guide rods.
优选的,每个所述安装口内均固定安装有安装环,每个所述安装环上均开设有用于转动连接螺杆的转动口,所述螺杆靠近安装环的部分未设有螺纹,所述显微镜主体位于安装槽内的部分也未设有螺纹。Preferably, a mounting ring is fixedly installed in each of the mounting ports, and each of the mounting rings is provided with a rotating port for rotating the connecting screw, and the part of the screw rod close to the mounting ring is not provided with threads, and the microscope The part of the main body that is located in the mounting groove is also not provided with threads.
优选的,所述螺杆的中心位置固定安装有隔块,所述第一外螺纹和第二外螺纹分别设置在隔块两侧的螺杆上。Preferably, a spacer is fixedly installed at the center of the screw, and the first external thread and the second external thread are respectively provided on the screw on both sides of the spacer.
与现有技术相比,本发明的有益效果是:Compared with prior art, the beneficial effect of the present invention is:
1、本发明通过液压机构、伺服电机、转轴、放置盘、载物件、放置槽实现了对载玻片的进样,减少了镜检人员更换载玻片的环节,从而一定程度上降低了镜检人员的工作强度,有利于镜检人员保持精力观察。1. The present invention realizes the sampling of the slide glass through the hydraulic mechanism, servo motor, rotating shaft, placement plate, object-carrying parts, and placement groove, which reduces the link of the microscope inspector to replace the slide glass, thus reducing the cost of the microscope to a certain extent. The working intensity of the inspectors is beneficial to the microscope inspectors to maintain energy for observation.
2、本发明通过手柄、螺杆、第一外螺纹、第二外螺纹、第一夹板、第二夹板、橡胶垫实现了对载玻片的夹持固定,从而可以同时夹持四个载玻片用于观察,同时通过橡胶垫可以避免对载玻片造成损伤。2. The present invention realizes the clamping and fixing of the glass slides through the handle, the screw, the first external thread, the second external thread, the first splint, the second splint, and the rubber pad, so that four slides can be clamped at the same time It is used for observation, and the rubber pad can avoid damage to the glass slide.
附图说明Description of drawings
图1为本发明提出的一种用于癌细胞显微镜自动进样装置的侧面结构示意图;Fig. 1 is a side structural schematic view of an automatic sampling device for cancer cell microscope proposed by the present invention;
图2为本发明提出的一种用于癌细胞显微镜自动进样装置放置盘的侧面结构示意图;Fig. 2 is a schematic diagram of the side structure of a placement tray for a cancer cell microscope automatic sampling device proposed by the present invention;
图3为图2的A处结构示意图。FIG. 3 is a schematic diagram of the structure at A in FIG. 2 .
图中:1观察台、2安装竖板、3液压机构、4伺服电机、5转轴、6放置盘、7载物件、8限位杆、9显微镜主体、10载物台、11手柄、12安装环、13第一夹板、14第二夹板、15放置槽、16螺杆。In the figure: 1 Observation platform, 2 Installation vertical plate, 3 Hydraulic mechanism, 4 Servo motor, 5 Rotating shaft, 6 Placement plate, 7 Loading object, 8 Limit rod, 9 Microscope main body, 10 Stage, 11 Handle, 12 Installation Ring, 13 first splints, 14 second splints, 15 placement grooves, 16 screw rods.
具体实施方式Detailed ways
下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention.
在本发明的描述中,需要理解的是,术语“上”、“下”、“前”、“后”、“左”、“右”、“顶”、“底”、“内”、 “外”等指示的方位或位置关系为基于附图所示的方位或位置关系,仅是为了便于描述本发明和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本发明的限制。In describing the present invention, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", " The orientation or positional relationship indicated by "outside", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, so as to Specific orientation configurations and operations, therefore, are not to be construed as limitations on the invention.
参照图1-3,一种用于癌细胞显微镜自动进样装置,包括观察台1、显微镜主体9和载物台10,显微镜主体9固定安装在观察台1上方的一侧,载物台10固定安装在显微镜主体9上,观察台1上方远离显微镜主体9的一侧固定安装有安装竖板2,安装竖板2靠近显微镜主体9的一侧固定安装有液压机构3,液压机构3的输出端固定安装有伺服电机4,液压机构3包括液压泵和活塞杆,输出端即为活塞杆远离液压泵的一端,伺服电机4的驱动端固定连接有转轴5,转轴5远离伺服电机4的一端固定连接有放置盘6,伺服电机4带有自锁功能,可以完成对放置盘6位置的固定,因此不需要再在载物台10上进行固定。Referring to Figures 1-3, an automatic sampling device for a cancer cell microscope includes an observation platform 1, a microscope body 9 and an object stage 10, the microscope body 9 is fixedly installed on the side above the observation stage 1, and the object stage 10 It is fixedly installed on the microscope main body 9, and the side above the observation table 1 away from the microscope main body 9 is fixedly installed with an installation vertical plate 2, and the side of the installation vertical plate 2 close to the microscope main body 9 is fixedly installed with a hydraulic mechanism 3, and the output of the hydraulic mechanism 3 Servo motor 4 is fixedly installed at the end, and hydraulic mechanism 3 includes a hydraulic pump and a piston rod. The output end is the end of the piston rod away from the hydraulic pump. Fixedly connected with the placement disc 6, the servo motor 4 has a self-locking function, which can complete the fixing of the position of the placement disc 6, so it does not need to be fixed on the object stage 10 again.
放置盘6远离转轴5的一侧环形固定安装有四个夹持件,每个夹持件均由两个载物件7组成,如图2示,相邻的两个载物件7之间通过两个限位杆8固定连接,两个限位杆8为对角设置,载玻片安装时位于两个限位杆8之间,放置槽15位于两个限位杆8之间,通过两个限位杆8的配合实现两个载物件7的固定连接的同时,可以将载玻片的观察范围限制在两个限位杆8之间,便于镜检人员快速找到观测位置,最上方的夹持件位于载物台10的上方。Placement plate 6 is fixedly installed with four clamping pieces in a ring on one side away from rotating shaft 5, and each clamping piece is all made up of two carrying objects 7, as shown in Figure 2, passes between two adjacent carrying objects 7. Two limit rods 8 are fixedly connected, and two limit rods 8 are arranged diagonally. When the slide is installed, it is positioned between the two limit rods 8, and the placement groove 15 is located between the two limit rods 8. The cooperation of the limit rod 8 realizes the fixed connection of the two objects 7, and at the same time, the observation range of the glass slide can be limited between the two limit rods 8, which is convenient for the microscope inspector to quickly find the observation position. The holder is located above the stage 10 .
两个载物件7相对的一侧均设有放置槽15,每个载物件7上均设有与放置槽15连通的安装口,安装口内转动连接有螺杆16,螺杆16远离放置槽15的一端固定安装有手柄11,每个放置槽15远离安装口一侧的内壁上均设有与螺杆16转动连接的安装槽,每个安装口内均固定安装有安装环12,每个安装环12上均开设有用于转动连接螺杆16的转动口,螺杆16靠近安装环12的部分未设有螺纹,显微镜主体9位于安装槽内的部分也未设有螺纹,通过安装环12可以实现螺杆16的安装,实现了螺杆16转动时位置不变,从而通过第一外螺纹和第二外螺纹使得第一夹板13和第二夹板14移动。The opposite sides of the two loading objects 7 are provided with placement grooves 15, and each loading object 7 is provided with an installation port communicating with the placement groove 15, and a screw rod 16 is rotatably connected in the installation opening, and the screw rod 16 is far away from one end of the placement groove 15. A handle 11 is fixedly installed, and each placement groove 15 is provided with a mounting groove that is rotatably connected with the screw rod 16 on the inner wall of each placement groove 15 away from the installation port, and a mounting ring 12 is fixedly installed in each mounting port, and each mounting ring 12 has There is a turning port for rotating the connecting screw 16. The part of the screw 16 close to the mounting ring 12 is not provided with threads, and the part of the microscope body 9 located in the mounting groove is not provided with threads either. The installation of the screw 16 can be realized through the mounting ring 12. It is realized that the position of the screw rod 16 remains unchanged when rotating, so that the first clamping plate 13 and the second clamping plate 14 are moved through the first external thread and the second external thread.
每个螺杆16上均设有第一外螺纹和第二外螺纹,第一外螺纹和第二外螺纹方向相反,螺杆16的中心位置固定安装有隔块,第一外螺纹和第二外螺纹分别设置在隔块两侧的螺杆16上,第一夹板13和第二夹板14对称设置在螺杆16的两侧,顺时针转动螺杆16,第一夹板13和第二夹板14相向移动,逆时针转动螺杆16,第一夹板13和第二夹板14相背移动,每个螺杆16位于放置槽15内的部分均通过第一外螺纹螺纹连接有第一夹板13,且通过第二外螺纹螺纹连接有第二夹板14,每个放置槽15内均固定安装有导杆,每个第一夹板13和每个第二夹板14上均开设有用于滑动连接导杆的滑口,通过导杆可以对第一夹板13和第二夹板14的移动方向进行限制,避免第一夹板13和第二夹板14轴向转动,影响载玻片的安装。Each screw 16 is provided with a first external thread and a second external thread, the direction of the first external thread and the second external thread are opposite, the center position of the screw 16 is fixedly installed with a spacer, the first external thread and the second external thread The first splint 13 and the second splint 14 are symmetrically arranged on both sides of the screw 16, and the screw 16 is rotated clockwise, and the first splint 13 and the second splint 14 move toward each other, counterclockwise Rotate the screw rod 16, the first clamping plate 13 and the second clamping plate 14 move away from each other, and the part of each screw rod 16 located in the placement groove 15 is threaded with the first clamping plate 13 through the first external thread, and is threaded through the second external thread. The second clamping plate 14 is arranged, and guide rods are fixedly installed in each placement groove 15, and each first clamping plate 13 and each second clamping plate 14 are provided with sliding openings for slidingly connecting the guide rods, through which the guide rods can be connected to each other. The moving directions of the first clamping plate 13 and the second clamping plate 14 are restricted to prevent the first clamping plate 13 and the second clamping plate 14 from rotating axially and affecting the installation of the slide glass.
第二夹板14位于第一夹板13的一侧,每个第一夹板13靠近第二夹板14的一侧均固定安装有第一橡胶垫,每个第二夹板14靠近第一夹板13的一侧均固定安装有第二橡胶垫,通过顺时针转动手柄11,可以配合第一外螺纹和第二外螺纹使得第一夹板13和第二夹板14相向移动,将载玻片夹紧,通过第一橡胶垫和第二橡胶垫可以避免夹紧过程中对载玻片造成损伤。The second clamping plate 14 is positioned at one side of the first clamping plate 13, and each first clamping plate 13 is fixedly equipped with a first rubber pad near the side of the second clamping plate 14, and each second clamping plate 14 is near the side of the first clamping plate 13. Both are fixedly installed with a second rubber pad, and by turning the handle 11 clockwise, the first clamping plate 13 and the second clamping plate 14 can be moved toward each other by cooperating with the first external thread and the second external thread, clamping the glass slide, passing through the first The rubber pad and the second rubber pad can avoid damage to the glass slide during the clamping process.
本发明中,使用者使用该装置时,将四个载玻片固定在四个夹持件上,将载玻片放置在第一夹板13和第二夹板14之间,通过顺时针转动手柄11,配合第一外螺纹和第二外螺纹使得第一夹板13和第二夹板14相向移动,将载玻片夹紧,通过第一橡胶垫和第二橡胶垫可以避免夹紧过程中对载玻片造成损伤,完成固定后,通过显微镜主体9对位于上方的载玻片进行观察,观察完毕后,需要更换时,控制液压机构3,液压机构3上的活塞杆收缩,使得放置盘6移动至显微镜主体9的一侧,开启伺服电机4,带动转轴5转动90°,使得另一个夹持件转动至正上方,此时正上方的夹持件位于载物台10上方的一侧,控制液压机构3,液压机构3上的活塞杆伸出,使得上方的夹持件移动至载物台10的正上方即可。In the present invention, when the user uses the device, he fixes four slides on the four clamping parts, places the slides between the first clamping plate 13 and the second clamping plate 14, and rotates the handle 11 clockwise , cooperate with the first external thread and the second external thread to make the first clamping plate 13 and the second clamping plate 14 move towards each other, clamp the glass slide, and the first rubber pad and the second rubber pad can avoid the damage to the slide glass during the clamping process. After the fixation is completed, observe the slide glass located above through the microscope main body 9. After the observation is completed, when it needs to be replaced, the hydraulic mechanism 3 is controlled, and the piston rod on the hydraulic mechanism 3 shrinks, so that the placement plate 6 moves to On one side of the main body 9 of the microscope, the servo motor 4 is turned on to drive the rotating shaft 5 to rotate 90°, so that the other clamping part rotates directly above. At this time, the clamping part directly above is located on the side above the stage 10. Mechanism 3, the piston rod on the hydraulic mechanism 3 is stretched out, so that the clamping piece above moves to the directly above the stage 10 .
以上所述,仅为本发明较佳的具体实施方式,但本发明的保护范围并不局限于此,任何熟悉本技术领域的技术人员在本发明揭露的技术范围内,根据本发明的技术方案及其发明构思加以等同替换或改变,都应涵盖在本发明的保护范围之内。The above is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto, any person familiar with the technical field within the technical scope disclosed in the present invention, according to the technical solution of the present invention Any equivalent replacement or change of the inventive concepts thereof shall fall within the protection scope of the present invention.
Claims (6)
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Application publication date: 20181116 |