CN108606811A - A kind of ultrasound stone age detecting system and its method - Google Patents

Abstract

The invention discloses an ultrasonic bone age detection system and a method thereof, including step 1: immersing the tissue to be measured in a coupling medium, immersing the scanning window part in the coupling medium and contacting the tissue to be measured, setting the contact pressure threshold and fixing the scan window; step 2: adjust the position and angle of the ultrasonic probe according to the ultrasonic image of the hand, so that the long axis of the ultrasonic probe is perpendicular to the cut plane of the tissue to be measured during the scanning process; step 3: set the scanning parameters, start scanning and obtain Ultrasonic bone age image of the tissue to be measured. The present invention obtains bone age characteristic area images through an ultrasonic bone age detection system to evaluate children's bone age. After one scan is completed, while ensuring imaging quality, the purpose of wide field of view can be achieved, and there is no problem of operator dependence. Children's skeletal system has more cartilage components, and the sound transmission conditions of ultrasound imaging are better than those of adults. Therefore, the ultrasonic bone age detection system and method thereof of the present invention are suitable for the detection of children's bone age.

Description

An ultrasonic bone age detection system and method thereof

technical field

The invention relates to the technical field of ultrasonic detection, in particular to an ultrasonic bone age detection system and a method thereof.

Background technique

At present, the bone age evaluation methods widely used at home and abroad are mainly Greulich-Pyle (G-P) atlas method and Tanner-Whitehouse (TW2) scoring method. In the 1990s, domestic scholars made appropriate revisions to the TW2 method based on the wrist data of teenagers aged 0-19 in my country, and formulated the Chinese bone maturity evaluation standard, namely the CHN method. All of the above methods require X-ray filming, which poses radiation hazards to children in the development and growth period, and repeated testing is not suitable, which limits the time limit for its clinical application.

In principle, all parts of the human skeleton can be used to estimate the degree of maturity, but because of the large number of bones in the wrist, there are 29 bones including carpal bones, metacarpal bones, phalanges, ulna and radius, and the medial sesamoid bone is also an important sign of bone development. And it is easy to film and protect, so it has many advantages in determining bone age. Therefore, at home and abroad, the method of taking X-ray films of wrist bones is often used to judge bone age.

During the development of normal bones, the appearance time and morphological changes of the primary and secondary ossification centers of the bones have a certain regularity, which is expressed in months or years, that is, bone age. Bone age is one of the most accurate methods to measure individual growth in medicine at present. Compared with physiological indicators such as weight and height, bone age can more accurately reflect the biological development level of children.

At present, the preliminary exploration of ultrasound technology for bone age determination mainly uses ultrasound to measure the thickness of femoral head cartilage. The researchers found that the femoral head cartilage thickness measured by ultrasound is closely related to bone age, actual age, height and weight, and can be used to determine bone age in children. However, the sensitivity of ultrasound detection is low, and it cannot replace the current commonly used clinical detection methods and is suitable for clinical screening. This method has only been tested in a small area, and has not been fully applied in clinical practice, and no consensus has been reached.

Ultrasound technology has certain reliability and operability in bone age determination research. The biggest advantage is that it fundamentally eliminates radiation damage and provides a more practical detection method for clinical follow-up observation. However, due to the short time for ultrasound to evaluate bone age, it is still in the stage of exploration and accumulation of experience; in addition, there are differences in the operation techniques of sonographers and the setting of acquisition system parameters, so there is still no unified and recognized standard for ultrasound evaluation of bone age. Some technical methods also require special equipment, which limits the application of this technology in bone age determination.

Contents of the invention

In order to solve the technical problems in the above background, the present invention discloses an ultrasonic bone age detection system and its method.

Technical scheme of the present invention is implemented like this:

The invention provides an ultrasonic bone age detection method, comprising the following steps:

Step 1: Immerse the tissue to be measured in the coupling medium, the coupling medium provides the acoustic coupling between the ultrasonic probe and the tissue to be measured, partially immerse the scanning window in the coupling medium and make contact with the surface of the tissue to be measured, and set the contact pressure threshold and fix the scan window;

Step 2: adjusting the position and angle of the ultrasonic probe according to the ultrasonic image of the tissue to be measured, so that the long axis of the ultrasonic probe is perpendicular to the cut plane of the tissue to be measured during the scanning process;

Step 3: Set the scan parameters, start the full volume scan and obtain the ultrasonic bone age image of the tissue to be tested.

Preferably, the tissue to be tested is a hand bone, and the coupling medium is one or more of water, crystal glue, crystal mud, gel and ultrasonic fluid.

Preferably, step 1-1: place the palm face down in the coupling medium containing device filled with water, and completely immerse the palm to the wrist in the water;

Step 1-2: The ultrasonic probe is close to the coupling medium holding device until the scanning window is partially immersed in water and in contact with the skin surface of the hand, the contact pressure threshold is adjusted and the scanning window is fixed, and the position and angle of the ultrasonic probe are adjusted. The long axis of the ultrasound probe is perpendicular to the cut plane of the hand during scanning.

Preferably, setting the scan parameters in step 3 includes setting the scan dynamic range to 30-70dB, the imaging depth to 5-6cm, the scan frequency to 7-11MHz, the scan time to 60-90S, and the scan layer thickness to be greater than or equal to 8mm and the overlapping part is 10% to 75%. Start the full volume scan from the wrist to the fingertips and obtain the ultrasound bone age images of the hand bones.

Preferably, in the step 3, it also includes extracting and displaying bone age feature region images from the dynamic and coherent coronal scan images and/or frame-by-frame static scan images from the skin of the palm to the back of the hand, wherein the bone age feature regions include One or more of the metacarpophalangine group and the carpal group, the metacarpophalangine group includes the distal end of the metacarpal, the proximal end of the proximal phalanx, and the proximal end of the distal phalanx, and the carpal group includes the radius, the ulna, and the carpus.

The present invention also provides an ultrasonic bone age detection system, comprising:

The coupling medium containing device is used for containing the coupling medium, allowing the tissue to be tested to be immersed in the coupling medium;

The full-volume scanning device includes an ultrasonic probe and a scanning window for scanning the tissue to be measured, allowing the scanning window to be immersed in the coupling medium;

a controller, connected to the ultrasonic probe, for adjusting the moving direction of the ultrasonic probe relative to the tissue to be measured;

The ultrasound bone age image generation device is connected to the ultrasound probe and is used to generate and display the ultrasound bone age image of the tissue to be measured.

Preferably, the tissue to be tested is a hand bone, and the coupling medium is one or more of water, crystal glue, crystal mud, gel and ultrasonic fluid.

Preferably, the controller is used to adjust the position of the ultrasonic probe relative to the tissue to be measured, and the controller also includes a pressure sensing module, so that the scanning window is in contact with the tissue to be measured during the scanning process and the contact pressure threshold is a fixed value, The fixed value is 0.8-1.2 lbs.

Preferably, it also includes a fixing support member, which is located in the coupling medium containing device and is used to fix and support the tissue to be measured.

Preferably, the ultrasonic bone age image generation device includes a bone age characteristic region image extraction module, which is used to extract and display bone age characteristic region images from the dynamic and coherent coronal scan images and/or frame-by-frame static scan images from the skin of the palm to the back of the hand , wherein, the bone age characteristic area includes one or more of the metacarpophalangine group and the carpal group, the metacarpophalangine group includes the distal end of the metacarpal, the proximal end of the proximal phalanx, and the proximal end of the distal phalanx, and the carpal group includes the radius , ulna, carpus.

The beneficial effect of implementing the present invention mainly contains:

The present invention obtains bone age characteristic area images through an ultrasonic bone age detection system, and evaluates the bone age of the left hand and left wrist. Different from the relatively macro vision provided by CT and MRI, traditional ultrasound can only display local information of tissues and organs, lacking a holistic view. The ultrasonic bone age detection system of the present invention better solves the above problems. After one scan, while ensuring the imaging quality, it can achieve the purpose of wide field of view, and there is no problem of operator dependence. Children's skeletal system has a lot of cartilage components, and the sound transmission conditions of ultrasound imaging are better than those of adults, especially at young ages, some carpal bones have not yet ossified, and the clinical principle of bone age detection is to observe the process of cartilage forming bone; skeletal muscle lesions are basically not affected by breathing, etc. It does not require too much cooperation from the children under examination. Therefore, the ultrasonic bone age detection system of the present invention is suitable for detection of children's wrists.

In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. Obviously, the accompanying drawings in the following description are only It is an embodiment of the present invention, and those skilled in the art can also obtain other drawings based on these drawings without any creative work.

Fig. 1 is a schematic flow chart of an ultrasonic bone age detection method in one embodiment;

Fig. 2 is an embodiment, the coronal ultrasound bone age image shows the child's hand structure;

Fig. 3 is an embodiment, the coronal ultrasound bone age image shows the structure diagram of adult's hand;

Fig. 4 is an image of a coronal bone age characteristic region in the prior art.

Detailed ways

The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

Embodiment one

An ultrasonic bone age detection system, comprising: a coupling medium containing device, used for containing the coupling medium, allowing the tissue to be tested to be immersed in the coupling medium. Wherein, the size of the coupling medium containing device is configured such that the tissue to be tested can be immersed in the liquid coupling medium contained therein.

The scanning device includes an ultrasonic probe and a scanning window for scanning the tissue to be measured, allowing the scanning window to be immersed in the coupling medium;

A controller, connected to the ultrasonic probe, is used to adjust the moving direction of the ultrasonic probe relative to the tissue to be measured. In this embodiment, the ultrasonic probe is installed in the scanning device driven by the controller, and can move up, down, left, and right and adjust the angle. The controller can adjust the position and angle of the ultrasonic probe according to the three-dimensional image of the tissue to be scanned, so that the long axis of the ultrasonic probe is perpendicular to the cut plane of the tissue to be measured during the scanning of the ultrasonic probe.

The ultrasound bone age image generation device is connected to the ultrasound probe and is used to generate and display the ultrasound bone age image of the tissue to be measured.

The tissue to be tested is a hand bone, preferably, the hand bone is a hand cartilage bone. The coupling medium is one or more of water, crystal glue, crystal mud, gel and ultrasonic liquid. The coupling medium acts as an acoustic coupling medium between the patient's hand bones and the ultrasound probe. In other embodiments, the coupling medium may also be other medical coupling gels.

The controller is used to adjust the position of the ultrasonic probe relative to the tissue to be tested, and the controller also includes a pressure sensing module, so that the scanning window is in contact with the tissue to be tested and the contact pressure threshold is a fixed value during the scanning process. The value is preferably between 0.8 and 1.2 lbs. Most preferably, the fixed value is 1 pound, the probe is directly close to the skin of the child's hand, and a pressure of 1 pound is applied each time to ensure that the probe is in full contact with the skin of the hand and the child does not feel pain. Preferably, the initial pressure of the contact pressure between the scanning window and the ultrasonic probe and the hand skin is 0, and the pressure is gradually increased to 1 pound. In this embodiment, a pressure sensor may also be provided on the scanning window for feeding back a pressure contact value and transmitting it to the pressure sensing module.

It also includes a fixed support, located in the water tank, used to fix and support the tissue to be tested. In other embodiments, the pressure sensor can be set in the fixed support to sense the position information of the tissue to be measured and adjust the pressure of the scan window on the skin of the tissue to be tested, and feedback the pressure contact value and transmit it to the pressure sensing module . Preferably, the upper part of the fixed support has a flexible support that makes the palm and the wrist in the same plane. The support may consist of a hydrogel-type medical ultrasound coupling patch.

The tissue to be tested is placed on the fixed support of the coupling medium holding device, and when it is judged that the tissue to be tested is placed unreasonably, the user is prompted to place the tissue to be tested correctly, and the user is re-judged whether the tissue to be tested is placed correctly. When it is judged that the contact pressure threshold is unreasonable, the user is prompted to readjust the scanning window and judge whether the contact pressure threshold is reasonable. When it is judged that the position of the tissue to be tested is correct and the contact pressure threshold is reasonable, start the ultrasonic bone age detection system to move the ultrasonic probe on the tissue to be tested to obtain the ultrasonic information of the tissue to be tested, and obtain a three-dimensional ultrasonic image of the tissue to be tested through computer conversion. In other embodiments, the ultrasonic bone age detection system can automatically perform ultrasonic scanning according to the three-dimensional scanning path, so as to reduce adverse factors in human operation.

In other embodiments, a temperature sensor for detecting the temperature of the coupling medium and a temperature regulator for adjusting the temperature of the coupling medium are also included.

As shown in FIG. 2 , the child's hand bones can be clearly seen in the child's ultrasonic imaging image obtained by using the ultrasonic bone age detection system in this embodiment. In this embodiment, the imaging parameters are: the dynamic range DynamicRange is lowered to 30dB to improve the contrast resolution, thereby improving bone display; the imaging depth Depth is increased to 5-6cm to display far-field images, thereby displaying all ranges of bones ;The frequency frequency is reduced to 7-11MHZ to improve the penetration of ultrasound, which helps to display the bones in the far field; preferably, children under the age of 7 increase the frequency Frequency to 11MHZ to improve the ultrasound resolution, and those over 7 years old Children reduce the frequency to 7MHZ to improve the penetration of ultrasound, which helps to display the bones in the far field. The focus is moved down to below the middle of the image to improve the image quality of the far field of the ultrasound image, which helps to display the bones in the far field; improving the dynamic tissue contrast enhancement DTCE to H level helps to reduce noise and improve contrast resolution, thereby Imaging of bones is clearer.

As shown in FIG. 3 , the adult ultrasonic imaging image obtained by using the ultrasonic bone age detection system in this embodiment can be seen that it cannot clearly display bones, but can only display muscles. Wherein, the imaging parameters are: Dynamic Range adjustment 70dB; imaging depth Depth 4cm; frequency Frequency 12MHZ; focus to the middle of the image; dynamic tissue contrast enhancement DTCE to L level.

The bone age detection system in this embodiment is configured with a full-volume scanning probe, and an ultra-wide and ultra-large scanning probe is used. The scanning width of the probe is 16.8cm, the adjustable frequency range is about 5-14MHz, and the maximum scanning depth is 6.0cm (can be adjusted according to the specific conditions of each lesion). One automatic scan can obtain 15.4cm×16.8cm×6.0cm The maximum volume image data information. In other embodiments, it may also be applicable to other operating systems. In this embodiment, the three-dimensional full-volume scanning technology is used, which can provide multi-layered coronal images, which cannot be achieved by traditional ultrasonic examination. In addition, the volume imaging can completely observe the structure of the hand from any plane, maximizing Reduced dependence on the operator. . The equipment combines three systems of automatic volume scanning, information acquisition and image processing. All these systems are organically combined with the high-frequency probe of automatic ultrasound volume imaging, and the original data of the scanned target area in the transverse position are reconstructed to obtain the coronal and sagittal positions. The image allows the physician to conduct multi-directional continuous observation of all volume data such as cross-sectional, coronal and sagittal planes on the ultrasound workbench after the test is completed, and conduct digital analysis by electronic computer. Doctors can evaluate and analyze lesions in multiple planes and angles by integrating multi-level imaging information, so as to improve the accuracy of diagnosis. The ultrasonic probe in this embodiment can scan the hand tissue in an all-round way with zero dead angle, avoiding the risk of traditional probes artificially scanning and missing scans; Hundreds of layers of hand tissue are observed layer by layer, which avoids secondary radiation damage caused by enhanced CT and other radiological examinations, which is beyond the reach of traditional color Doppler ultrasound. It not only scans the entire hand tissue comprehensively, but also can Carry out hierarchical research; the image processing technology of the ultrasonic bone age detection system in this embodiment can perform three-dimensional positioning of the hand bones from three different directions of the sagittal plane, coronal plane and transverse plane, and provide more accurate bone age detection. information.

Embodiment two

This implementation provides an ultrasonic bone age detection method in combination with the ultrasonic bone age detection system in Embodiment 1, which includes the following steps:

Step 1: Immerse the tissue to be measured in the coupling medium, which provides the acoustic coupling between the ultrasonic probe and the tissue to be measured; partially immerse the scanning window in the coupling medium and make contact with the surface of the tissue to be measured, adjust the contact pressure threshold and Fixed scan window. Wherein, the tissue to be tested is a hand bone, preferably, the hand bone is a hand cartilage bone. The coupling medium is one or more of water, crystal glue, crystal mud, gel and ultrasonic liquid.

When scanning, immerse your left hand in water, place a scanning window above it, and partially immerse the scanning window in water, just touch the surface of the probe with the skin on the back of the hand, then set the contact pressure threshold and fix the scanning window. The long axis of the ultrasonic probe is perpendicular to the cut surface of the tissue to be measured. After fixing the scanning window, adjust the parameters, and perform one-button automatic scanning from the wrist to the fingertips. After scanning, the system automatically performs three-dimensional reconstruction on the original transverse data, and displays the reconstructed coronal image on the workstation. It can obtain dynamic and coherent coronal scans from the palm to the back of the hand, and can also obtain frame-by-frame static images. Physicians can view and analyze images through the workstation, and can also perform image adjustments.

Specifically, the following steps are included:

Step 1-1: Put the palm face down in the coupling medium containing device filled with water, and completely immerse the palm to the wrist in the water. Wherein, preferably, the water is warm water at 20-25° C., which can avoid the influence of temperature on the scanning and avoid discomfort of the patient. The hand is from the wrist to the fingertips of the left hand. In other embodiments, the palm facing up and other suitable placement postures may also be adopted according to the actual situation.

Step 1-2: The ultrasonic probe is close to the coupling medium holding device until the scanning window is partially immersed in water and in contact with the skin surface of the hand, setting the contact pressure threshold between the scanning window and the skin during scanning, adjusting the scanning window and Fix the scanning window and adjust the position and angle of the ultrasonic probe. During the scanning process, the long axis of the ultrasonic probe is perpendicular to the cut plane of the hand. In this embodiment, the position of the ultrasonic probe is manually adjusted, because each child's hand shape is different, and it is more accurate to manually adjust the position of the probe. In other embodiments, the contact pressure threshold and the position and angle of the ultrasonic probe can also be automatically adjusted according to the three-dimensional ultrasonic image.

The scanning window is pressed against the skin surface to ensure that the long axis of the ultrasonic probe is perpendicular to the cut plane of the tissue to be measured when the ultrasonic probe is scanning. The scanning window and the skin are in close contact to form a cut surface, which can reduce the low quality of the scanned image caused by interference images. If the acquired pressure signal is greater than the contact pressure threshold, that is, the scanning window is too close to the skin, adjust the scanning window so that the ultrasonic probe is lifted upwards and the height becomes higher; if the acquired pressure signal is less than the contact pressure threshold, that is, the scanning window If the contact with the skin is not close or does not touch the skin, adjust the scanning window so that the ultrasonic probe is pressed down and the height becomes lower. During the scanning process, the scanning window is in contact with the tissue to be measured and the contact pressure threshold is a fixed value, preferably 0.8-1.2 pounds, most preferably 1 pound.

Preferably, before step 1-2, the following steps are further included: setting the scanning direction during scanning, and the number of groups of scanned two-dimensional images is N.

Step 2: Automatically adjust the position and angle of the ultrasonic probe according to the three-dimensional ultrasonic image of the hand, so that the long axis of the ultrasonic probe is perpendicular to the cut plane of the tissue to be measured during the scanning process.

Step 3: Set the scanning parameters, start full-volume scanning and obtain ultrasound images of the tissue to be tested.

Among them, setting the scanning parameters specifically includes setting the scanning dynamic range to 30-70 dB, the imaging depth to 5-6 cm, the scanning frequency to 7-11 MHz and the scanning time to 60-90 s. Preferably, the scanning dynamic range is 30-50 dB, and most preferably, the scanning dynamic range is 30 dB. Preferably, the scan time is set to 60s (fast) or 90s (slow). After the operator selects the detection conditions, the volume scan can be started with one button, and the full volume information can be obtained for each scan, and a coronal scan image that is dynamic and coherent from the palm to the back of the hand can be obtained, and frame-by-frame static images can also be obtained. The layer distance set during scanning is smaller than the layer thickness, and adjacent scanning layers partially overlap. The slice thickness of each scan is greater than or equal to 8mm, and the overlap is 10% to 75%, which can quickly cover the entire left wrist to fingertips of infants to adolescents. Preferably, the scanning slice thickness is 8 mm, and the overlapping portion overlap is 75%. After setting the post-parameters, a full-volume scan of the wrist to the fingertips is started and an ultrasound bone age image of the hand skeleton is obtained.

In other embodiments, in the step 3, it also includes extracting and displaying bone age feature region images from the dynamic and coherent coronal scan images and/or frame-by-frame static scan images from the skin of the palm to the back of the hand, wherein the bone age features The region includes one or more of the metacarpophalangine group and the carpal group, the metacarpophalangine group includes the distal end of the metacarpal, the proximal end of the proximal phalanx, and the proximal end of the distal phalanx, and the carpal group includes the radius, ulna, and carpus. Wherein, the dynamic coherent coronal scan image can clearly display the adjacent relationship of the bone structure. A structure can only be considered to be displayed when it can be displayed relatively completely and clearly in a group of dynamic coherent images.

Preferably, in this embodiment, the ultrasonic bone age detection system carries out multiple static acquisitions of the coronal scan images of the hand according to the anatomical plane from shallow to deep, and obtains the depth distribution map corresponding to the image of the bone age characteristic region obtained through multiple scans , that is, those depths that can clearly display bone age characteristic region images for bone age detection. Extract multiple pre-analyzed bone age characteristic region images according to the depth distribution map, and further compare and analyze the pre-analyzed bone age characteristic region images with standard bone age characteristic region images to extract and display the bone age characteristic region images. For example, in one embodiment, the frame-by-frame static scan images can be automatically extracted and combined with multiple images of bone age feature regions to analyze the bone age of children.

In other embodiments, the reconstructed three-dimensional digital images may also include coronal reconstructed images and cross-sectional images, and bone age detection is performed through the three-dimensional reconstructed stereo images. Reconstructing the acquired N groups of two-dimensional images to obtain a three-dimensional digital image, where N is an integer greater than or equal to two.

Since the ultrasonic bone age image obtained in this embodiment has not only static two-dimensional images but also dynamic three-dimensional images, bone age characteristic areas and methods different from those of the prior art can be selected for bone age judgment according to actual needs. As shown in Figure 4, in the prior art, when judging the bone age through the bones of the hand, it is often judged by comparing one joint with one joint, a, b, c, d in Figure 4 (II) Among them, a, , b, c, and d correspond one-to-one, and the areas shown by a, b, c, and d are different joint areas.

Preferably, as shown in FIG. 2 , in this embodiment, the carpal group of the child's wrist is used to determine the bone age of the child. Specifically, when performing bone age detection, a dynamic and coherent coronal scan of the child’s wrist as shown in Figure 2 will be performed, and then the dynamic and coherent coronal scan image (not shown in the figure) will be combined with the automatically extracted static image of the bone age characteristic area. Ultrasound images (Figure 2 is one of the frames) were scanned to comprehensively determine the bone age of children.

As shown in Figure 3, the bones of the hand of an adult cannot be clearly displayed, only the muscular system can be presented. This is because children’s skeletal system has a lot of cartilage components, and ultrasound imaging conditions are better than adults’. Especially, some carpal bones at young ages have not yet ossified, and the clinical principle of bone age detection is to observe the process of cartilage forming bone; skeletal muscle lesions are basically not Affected by breathing, etc., it does not require too much cooperation from the child under examination. Therefore, the ultrasonic bone age detection system of the present invention is suitable for detection of children's wrists.

In this embodiment, after the scanning is completed, the system saves the frame-by-frame static scanning images and 3D reconstructed images, and displays the reconstructed coronal images on the workstation. Physicians can view and analyze the images through the workstation, and at the same time adjust the images, so as to realize telemedicine Long-term storage of diagnostics and data.

The bone age detection system in this embodiment can completely observe the internal structure from any plane, and can fully display the coronal images of the hand bones through two-dimensional and three-dimensional. The imaging information is multi-plane and multi-angle to evaluate and analyze the lesion, so as to improve the accuracy of diagnosis.

Within the scope of the knowledge and ability level of those skilled in the art, the various embodiments or technical features mentioned in the embodiments herein can be combined with each other as other optional embodiments without conflict, which are not The limited number of optional embodiments listed one by one, formed by the combination of a limited number of technical features, still belong to the technical scope disclosed in the present invention, and are also understood or inferred by those skilled in the art in combination with the drawings and the above and derived.

Finally, it should be pointed out that the above-listed embodiments are more typical and preferred embodiments of the present invention, and are only used to describe and explain the technical solutions of the present invention in detail, so as to facilitate readers' understanding, and are not intended to limit the present invention. protection scope or application. Therefore, any modification, equivalent replacement, improvement and other technical solutions made within the spirit and principles of the present invention shall be covered within the protection scope of the present invention.

Claims (10)

1. an ultrasonic bone age detection method, is characterized in that, comprises the following steps: Step 1: Immerse the tissue to be measured in a coupling medium, the coupling medium provides acoustic coupling between the ultrasonic probe and the tissue to be measured, and partially immerse the scanning window in the coupling medium and contact the surface of the tissue to be measured contact, setting a contact pressure threshold and fixing the scan window; Step 2: adjusting the position and angle of the ultrasonic probe according to the ultrasonic image of the tissue to be measured, so that the long axis of the ultrasonic probe is perpendicular to the cut plane of the tissue to be measured during the scanning process; Step 3: Set the scan parameters, start the full volume scan and obtain the ultrasonic bone age image of the tissue to be tested. 2. The ultrasonic bone age detection method according to claim 1, characterized in that: the tissue to be measured is a hand bone, and the coupling medium is one of water, crystal glue, crystal mud, gel and ultrasonic liquid and above. 3. The ultrasonic bone age detection method according to claim 2, characterized in that: Step 1-1: Place the palm face down in the coupling medium container filled with water, and fully immerse the palm to the wrist in the water; Step 1-2: The ultrasonic probe is close to the coupling medium containing device until the scanning window is partially immersed in water and in contact with the skin surface of the hand, the contact pressure threshold is set and the scanning window is fixed, and the ultrasonic probe is adjusted The long axis of the ultrasonic probe is perpendicular to the cut plane of the hand during the scanning process, wherein the contact pressure threshold is a fixed value, and the fixed value is 0.8-1.2 pounds. 4. The ultrasonic bone age detection method according to claim 2, characterized in that: setting the scanning parameters in the step 3 includes setting the scanning dynamic range to 30-70 dB, the imaging depth to 5-6 cm, and the scanning frequency to 7-6 cm. 11MHz, scan time 60-90S, scan slice thickness ≥ 8mm and overlap 10%-75%, start full-volume scanning from wrist to fingertips and obtain ultrasound bone age images of hand bones. 5. The ultrasonic bone age detection method according to claim 2, characterized in that: in said step 3, it also includes extracting from the dynamic and coherent coronal scan images and/or frame-by-frame static scan images from the skin of the palm to the back of the hand. The bone age characteristic area image is displayed, wherein, the bone age characteristic area includes one or more of the metacarpophalangine group and the carpal group, and the metacarpophalangine group includes the distal end of the metacarpal, the proximal end of the proximal phalanx, and the proximal end of the distal phalanx, The carpal group includes radius, ulna, and carpal bone. 6. An ultrasonic bone age detection system, characterized in that, comprising: Coupling medium containing device, used for containing the coupling medium, allowing the tissue to be tested to be immersed in the coupling medium; The full-volume scanning device includes an ultrasonic probe and a scanning window for scanning the tissue to be measured, allowing the scanning window to be immersed in the coupling medium; a controller, connected to the ultrasonic probe, for adjusting the moving direction of the ultrasonic probe relative to the tissue to be measured; The ultrasound bone age image generation device is connected to the ultrasound probe and is used to generate and display the ultrasound bone age image of the tissue to be measured. 7. The ultrasonic bone age detection system according to claim 6, characterized in that: the tissue to be measured is a hand bone, and the coupling medium is one of water, crystal glue, crystal mud, gel and ultrasonic liquid and above. 8. The ultrasonic bone age detection system according to claim 7, characterized in that: the controller is used to adjust the position of the ultrasonic probe relative to the tissue to be tested, and the controller also includes a pressure sensing module, so that when scanning During the process, the scanning window is in contact with the tissue to be tested and the contact pressure threshold is a fixed value, and the fixed value is 0.8-1.2 pounds. 9 . The ultrasonic bone age detection system according to claim 7 , further comprising a fixing support member, located in the coupling medium containing device, for fixing and supporting the tissue to be tested. 10 . 10. The ultrasonic bone age detection system according to claim 7, characterized in that: said ultrasonic bone age image generation device includes a bone age characteristic region image extraction module for dynamic and coherent coronal scan images from palm skin to dorsum skin and /or extract and display bone age characteristic area images from frame-by-frame static scanning images, wherein, the bone age characteristic area includes one or more of the metacarpophalangine group and the carpal group, and the metacarpophalangine group includes the distal end of the metacarpal bone and the proximal phalanx The proximal end and the proximal end of the distal phalanx, the carpal group includes radius, ulna, and carpal bone.