CN108451810A - A kind of shower cream and preparation method thereof - Google Patents
A kind of shower cream and preparation method thereof Download PDFInfo
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- CN108451810A CN108451810A CN201810273412.0A CN201810273412A CN108451810A CN 108451810 A CN108451810 A CN 108451810A CN 201810273412 A CN201810273412 A CN 201810273412A CN 108451810 A CN108451810 A CN 108451810A
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- Prior art keywords
- acid
- shower cream
- added
- sodium
- vitamin
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- 239000006071 cream Substances 0.000 title claims abstract description 53
- 238000002360 preparation method Methods 0.000 title abstract description 6
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims abstract description 27
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims abstract description 27
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 24
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000002253 acid Substances 0.000 claims abstract description 20
- 239000000203 mixture Substances 0.000 claims abstract description 20
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 19
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 18
- 230000000844 anti-bacterial effect Effects 0.000 claims abstract description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 18
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 16
- 229930195729 fatty acid Natural products 0.000 claims abstract description 16
- 239000000194 fatty acid Substances 0.000 claims abstract description 16
- -1 fatty acid ester Chemical class 0.000 claims abstract description 14
- 239000003755 preservative agent Substances 0.000 claims abstract description 14
- 230000002335 preservative effect Effects 0.000 claims abstract description 14
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 claims abstract description 12
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 12
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000005844 Thymol Substances 0.000 claims abstract description 12
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims abstract description 12
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 claims abstract description 12
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229940031439 squalene Drugs 0.000 claims abstract description 12
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229960000790 thymol Drugs 0.000 claims abstract description 12
- 235000019441 ethanol Nutrition 0.000 claims abstract description 10
- 239000011780 sodium chloride Substances 0.000 claims abstract description 9
- 229940065859 sodium cocoyl glycinate Drugs 0.000 claims abstract description 9
- IKGKWKGYFJBGQJ-UHFFFAOYSA-M sodium;2-(dodecanoylamino)acetate Chemical compound [Na+].CCCCCCCCCCCC(=O)NCC([O-])=O IKGKWKGYFJBGQJ-UHFFFAOYSA-M 0.000 claims abstract description 9
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 claims abstract description 9
- 229920000289 Polyquaternium Polymers 0.000 claims abstract description 8
- 229930003270 Vitamin B Natural products 0.000 claims abstract description 8
- 239000000686 essence Substances 0.000 claims abstract description 8
- 239000011720 vitamin B Substances 0.000 claims abstract description 8
- 235000019156 vitamin B Nutrition 0.000 claims abstract description 8
- RXSVKUSMDPFWFZ-UHFFFAOYSA-N CCCCCC([Na])CC.OC(=O)CC(C(O)=O)S(O)(=O)=O Chemical compound CCCCCC([Na])CC.OC(=O)CC(C(O)=O)S(O)(=O)=O RXSVKUSMDPFWFZ-UHFFFAOYSA-N 0.000 claims abstract description 7
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 6
- FPVVYTCTZKCSOJ-UHFFFAOYSA-N Ethylene glycol distearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOC(=O)CCCCCCCCCCCCCCCCC FPVVYTCTZKCSOJ-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000005639 Lauric acid Substances 0.000 claims abstract description 6
- 235000021314 Palmitic acid Nutrition 0.000 claims abstract description 6
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 6
- 229940100608 glycol distearate Drugs 0.000 claims abstract description 6
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 claims abstract description 6
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 6
- 239000011718 vitamin C Substances 0.000 claims abstract description 6
- WVYADZUPLLSGPU-UHFFFAOYSA-N salsalate Chemical compound OC(=O)C1=CC=CC=C1OC(=O)C1=CC=CC=C1O WVYADZUPLLSGPU-UHFFFAOYSA-N 0.000 claims description 40
- 238000003756 stirring Methods 0.000 claims description 21
- 229960000953 salsalate Drugs 0.000 claims description 20
- 150000002148 esters Chemical class 0.000 claims description 14
- 239000000419 plant extract Substances 0.000 claims description 14
- 241000196324 Embryophyta Species 0.000 claims description 8
- WWZKQHOCKIZLMA-UHFFFAOYSA-M octanoate Chemical compound CCCCCCCC([O-])=O WWZKQHOCKIZLMA-UHFFFAOYSA-M 0.000 claims description 8
- 238000006243 chemical reaction Methods 0.000 claims description 6
- TWJNQYPJQDRXPH-UHFFFAOYSA-N 2-cyanobenzohydrazide Chemical compound NNC(=O)C1=CC=CC=C1C#N TWJNQYPJQDRXPH-UHFFFAOYSA-N 0.000 claims description 5
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical group OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 5
- 235000021360 Myristic acid Nutrition 0.000 claims description 5
- TUNFSRHWOTWDNC-UHFFFAOYSA-N Myristic acid Natural products CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 229960005323 phenoxyethanol Drugs 0.000 claims description 5
- 241000220287 Sedum rubrotinctum Species 0.000 claims description 3
- YIMPWKCGMBWFMF-UHFFFAOYSA-N ethane-1,2-diol;hexadecanoic acid Chemical compound OCCO.CCCCCCCCCCCCCCCC(O)=O YIMPWKCGMBWFMF-UHFFFAOYSA-N 0.000 claims description 3
- 238000009413 insulation Methods 0.000 claims description 3
- MRUAUOIMASANKQ-UHFFFAOYSA-O carboxymethyl-[3-(dodecanoylamino)propyl]-dimethylazanium Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(O)=O MRUAUOIMASANKQ-UHFFFAOYSA-O 0.000 claims 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 claims 1
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 abstract description 6
- 208000003251 Pruritus Diseases 0.000 abstract description 3
- 230000007803 itching Effects 0.000 abstract description 3
- 241000219000 Populus Species 0.000 abstract 1
- 235000011118 potassium hydroxide Nutrition 0.000 abstract 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 19
- 230000000052 comparative effect Effects 0.000 description 14
- 230000000694 effects Effects 0.000 description 11
- 206010015150 Erythema Diseases 0.000 description 7
- 206010030113 Oedema Diseases 0.000 description 7
- 231100000321 erythema Toxicity 0.000 description 7
- 230000007794 irritation Effects 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- 238000005406 washing Methods 0.000 description 4
- 241000191967 Staphylococcus aureus Species 0.000 description 3
- 238000013329 compounding Methods 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000002195 synergetic effect Effects 0.000 description 3
- WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 2
- WBYWAXJHAXSJNI-SREVYHEPSA-N Cinnamic acid Chemical compound OC(=O)\C=C/C1=CC=CC=C1 WBYWAXJHAXSJNI-SREVYHEPSA-N 0.000 description 2
- 206010051814 Eschar Diseases 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 239000013040 bath agent Substances 0.000 description 2
- 229930016911 cinnamic acid Natural products 0.000 description 2
- 235000013985 cinnamic acid Nutrition 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 231100000333 eschar Toxicity 0.000 description 2
- 210000004209 hair Anatomy 0.000 description 2
- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 description 2
- 239000000344 soap Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 244000025254 Cannabis sativa Species 0.000 description 1
- 244000060011 Cocos nucifera Species 0.000 description 1
- 235000013162 Cocos nucifera Nutrition 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 206010072170 Skin wound Diseases 0.000 description 1
- 244000061458 Solanum melongena Species 0.000 description 1
- 241000251778 Squalus acanthias Species 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000004567 concrete Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 210000000245 forearm Anatomy 0.000 description 1
- 239000011086 glassine Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- HLERILKGMXJNBU-UHFFFAOYSA-N norvaline betaine Chemical compound CCCC(C([O-])=O)[N+](C)(C)C HLERILKGMXJNBU-UHFFFAOYSA-N 0.000 description 1
- FATBGEAMYMYZAF-KTKRTIGZSA-N oleamide Chemical compound CCCCCCCC\C=C/CCCCCCCC(N)=O FATBGEAMYMYZAF-KTKRTIGZSA-N 0.000 description 1
- FATBGEAMYMYZAF-UHFFFAOYSA-N oleicacidamide-heptaglycolether Natural products CCCCCCCCC=CCCCCCCCC(N)=O FATBGEAMYMYZAF-UHFFFAOYSA-N 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000036559 skin health Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000022 skin irritation / corrosion Toxicity 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
- 230000037314 wound repair Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of shower creams and preparation method thereof, it includes Thymol, the double poplar acid of water, ethyl alcohol, propylene glycol, lauric acid, myristic acid, palmitic acid, potassium hydroxide, glycol distearate, sulfosuccinic acid ethylhexyl sodium, Cocoamidopropyl betaine, sodium cocoyl glycinate, polyquaternium 7, polyglyceryl fatty acid ester composition, tetrasodium ethylenediamine tetraacetate, sodium chloride, acetic acid, essence, preservative, water, squalene, vitamin B and vitamin C, the mild pro-skin of shower cream of the present invention, it can effective anti-bacteria wet keeping, particularly suitable for there is the crowd of skin itching and body moss use.
Description
Technical field
The invention belongs to shower cream articles for use fields, and in particular to a kind of shower cream and preparation method thereof.
Background technology
Shower cream is also known as bath oil, refers to a kind of liquid ceanser used when having a bath, is that a kind of modern is common
Cleaning supplies, the invention of bath oil is primarily to substitution tradition cleans the sense of touch and effect of soap.
Bath oil does not have very hard feeling as soap, the effect of amino acid bath foam when contacting people's skin
Especially apparent, it is more relatively low that amino acid shower cream compares the shower cream pH value that Sulfates surfactant is raw material, mild moist
Skin will not cause strong acid-base to stimulate skin.
The antibacterial effect of traditional shower cream is to be improved, especially to the resistance of staphylococcus aureus deficiency, together
When there is also the bad situation of moistening effect, how to improve the anti-bacteria wet keeping effect of shower cream makes its nonirritant become ability again
The technological difficulties in domain.
Invention content
The purpose of the present invention is to provide a kind of shower cream, can effective anti-bacteria wet keeping, particularly suitable for there is skin itching
And the crowd of body moss uses.
The present invention is by the following technical programs to realize above-mentioned purpose, a kind of shower cream, including following weight percent
The component of meter：Thymol 0.1 ~ 0.5%, ethyl alcohol 0.2 ~ 1%, propylene glycol 0.5 ~ 3.5%, lauric acid 2 ~ 8%, myristic acid 4 ~ 9%,
Palmitic acid 2 ~ 8%, potassium hydroxide 1.5 ~ 6%, glycol distearate 1 ~ 2%, sulfosuccinic acid ethylhexyl sodium 1 ~ 5%, coconut palm
Oleamide propyl betaine 3 ~ 7%, sodium cocoyl glycinate 1 ~ 5%, polyquaternium -7 0.1 ~ 1.5%, polyglyceryl fatty acid ester group
Close object 0.3 ~ 3%, tetrasodium ethylenediamine tetraacetate 0.1 ~ 1%, sodium chloride 0.2 ~ 1.5%, essence 0.2 ~ 1%, water 30 ~ 80%, salicyl salicylate (salsalate)
0.1 ~ 0.5%, acetic acid 0.1 ~ 1%, squalene 0.1 ~ 1%, vitamin B 0.3 ~ 1%, vitamin C 0.1 ~ 1% and preservative 0.1 ~
0.3%。
Preferably, the preservative is Phenoxyethanol.
Preferably, the polyglyceryl fatty acid ester composition includes -4 certain herbaceous plants with big flowers acid esters of -6 caprylate of polyglycereol and polyglycereol.
Preferably, the shower cream further includes plant extracts 0.2 ~ 2.0%.
A method of shower cream is prepared, is included the following steps：
（1）Thymol, salicyl salicylate (salsalate) are added to be dissolved to transparent in ethyl alcohol, add plant extracts, propylene glycol stir to
It is fully transparent, it is prepared into bactericidal composition, it is spare；
（2）Potassium hydroxide is added into the water of component weight 45 ~ 55% to dissolve and stir evenly, lauric acid, Pork and beans is then added
Cool acid, palmitic acid ethylene glycol distearyl acid, sulfosuccinic acid ethylhexyl sodium, are persistently stirred and heated to 75 DEG C, insulation reaction
25~35min；
（3）After the completion of reaction, Cocoamidopropyl betaine, polyglyceryl fatty acid ester composition is added, and stir evenly, system
55 DEG C are cooled to, sodium cocoyl glycinate, polyquaternium -7 is added, and stir evenly；
（4）System is cooled to 35 DEG C, tetrasodium ethylenediamine tetraacetate, sodium chloride, acetic acid, essence is then added into system, stirring is extremely
It is completely dissolved；
（5）Enter step（1）Bactericidal composition, stir evenly, be eventually adding preservative, water, squalene, vitamin B and Wei Sheng
Plain C, stirs evenly.
Plant extracts of the present invention contains 55% burning celestial grass extract, 25% Honegsukle flower P.E and 20%
Tea polyphenols have good antibacterial and bacteriostasis.Shower cream of the present invention is particularly suitable for having skin itching and the crowd of body moss to make
With.
Advantageous effect：Shower cream antibacterial effect of the present invention is strong, to the killing rate of staphylococcus aureus up to 99.9%；This hair
Bright shower cream moisture-keeping efficacy is remarkable；Shower cream anti-bacteria wet keeping effect of the present invention is good, while present invention shower is nonirritant.
Specific implementation mode
The present invention is further described below by way of specific implementation mode, but the present invention is not limited only to following embodiment.
In the scope of the present invention or do not departing from present disclosure, in spirit and scope, to shower cream of the present invention and its
Preparation method is suitably modified, replaces the identical component of effect, it will become apparent to those skilled in the art that it
Be considered as being included within the scope of the present invention.
Embodiment 1：
A kind of shower cream includes the component of following weight percent meter：Thymol 0.25%, ethyl alcohol 0.6%, propylene glycol 2%, the moon
Cinnamic acid 5%, myristic acid 7%, palmitic acid 5%, potassium hydroxide 3.5%, glycol distearate 1.5%, sulfosuccinic acid diethyl
Own ester sodium 3%, Cocoamidopropyl betaine 5%, sodium cocoyl glycinate 3%, polyquaternium -7 0.8%, polyglyceryl fatty acid ester
Composition 1.7%, tetrasodium ethylenediamine tetraacetate 0.5%, sodium chloride 0.8%, essence 0.6%, water 65%, 0.55 spiny dogfish of sour 0.25 acetic acid
Preservative described in alkene 0.6,0.6% vitamin C 0.5 of vitamin B and preservative 0.19% is Phenoxyethanol；The polyglycereol fat
Acid ester composite includes -4 certain herbaceous plants with big flowers of -6 caprylate of polyglycereol and polyglycereol；The shower cream further includes plant extracts 1%.
A method of shower cream is prepared, is included the following steps：
（1）Thymol, salicyl salicylate (salsalate) are added to be dissolved to transparent in ethyl alcohol, add plant extracts, propylene glycol stir to
It is fully transparent, it is prepared into bactericidal composition, it is spare；
（2）Potassium hydroxide is added into the water of component weight 45 ~ 55% to dissolve and stir evenly, lauric acid, Pork and beans is then added
Cool acid, palmitic acid ethylene glycol distearyl acid, sulfosuccinic acid ethylhexyl sodium, are persistently stirred and heated to 75 DEG C, insulation reaction
25~35min；
（3）After the completion of reaction, Cocoamidopropyl betaine, polyglyceryl fatty acid ester composition is added, and stir evenly, system
55 DEG C are cooled to, sodium cocoyl glycinate, polyquaternium -7 is added, and stir evenly；
（4）System is cooled to 35 DEG C, tetrasodium ethylenediamine tetraacetate, sodium chloride, acetic acid, essence is then added into system, stirring is extremely
It is completely dissolved；
（5）Enter step（1）Bactericidal composition, stir evenly, be eventually adding preservative, water, squalene, vitamin B and Wei Sheng
Plain C, stirs evenly.
Embodiment 2：
A kind of shower cream includes the component of following weight percent meter：Thymol 0.1%, ethyl alcohol 0.2%, propylene glycol 0.5%, the moon
Cinnamic acid 2%, myristic acid 4%, palmitic acid 2%, potassium hydroxide 1.5%, glycol distearate 1%, sulfosuccinic acid diethyl oneself
Ester sodium 1%, Cocoamidopropyl betaine 3%, sodium cocoyl glycinate 1%, polyquaternium -7 0.1%, polyglyceryl fatty acid ester group
Close object 0.3%, tetrasodium ethylenediamine tetraacetate 0.1%, sodium chloride 0.2%, essence 0.2%, water 30%, salicyl salicylate (salsalate) 0.1%, acetic acid
0.1%, squalene 0.1%, vitamin B 0.3%, vitamin C 0.1% and preservative 0.1%；The preservative is Phenoxyethanol；Institute
It includes -4 certain herbaceous plants with big flowers acid esters of -6 caprylate of polyglycereol and polyglycereol to state polyglyceryl fatty acid ester composition；The shower cream further includes plant
Extract 0.2%.
The method of shower cream is prepared with embodiment 1.
Embodiment 3：
A kind of shower cream includes the component of following weight percent meter：Thymol 0.5%, ethyl alcohol 1%, propylene glycol 3.5%, bay
Acid 8%, myristic acid 9%, palmitic acid 8%, potassium hydroxide 6%, glycol distearate 2%, sulfosuccinic acid ethylhexyl sodium
5%, Cocoamidopropyl betaine 7%, sodium cocoyl glycinate 5%, polyquaternium -7 1.5%, polyglyceryl fatty acid ester composition
3%, tetrasodium ethylenediamine tetraacetate 1%, sodium chloride 1.5%, essence 1%, water 80%, salicyl salicylate (salsalate) 0.5%, acetic acid 1%, squalene 1%, dimension
Raw element B 1%, vitamin C 1% and preservative 0.3%；The preservative is Phenoxyethanol；The polyglyceryl fatty acid ester composition
Including -4 certain herbaceous plants with big flowers acid esters of -6 caprylate of polyglycereol and polyglycereol；The shower cream further includes plant extracts 2.0%.
The method of shower cream is prepared with embodiment 1.
Comparative example 1：
Plant extracts is become 0 from 15g, Thymol is from 2.5g becomes 10g, salicyl salicylate (salsalate) becomes 10g from 2.5g, other groups
Divide and prepares with embodiment 1.
Comparative example 2：
Thymol is become 0, salicyl salicylate (salsalate) from 2.5g becomes 0 from 2.5g, and plant extracts becomes 20g, other components from 15g
With preparation with embodiment 1.
Comparative example 3：
Polyglyceryl fatty acid ester composition is become 0 from 10g, squalene becomes 15g from 5g, other components and prepares same embodiment
1。
Comparative example 4：
Squalene is become into 0g from 5g, polyglyceryl fatty acid ester composition becomes 15 from 10g, other components and prepares same embodiment
1。
Test example one：
The anti-microbial property test of shower cream of the present invention
According to GB19877.2-2005《Extraordinary bath agent》Measure shower cream prepared by the embodiment of the present invention 1 ~ 3 and comparative example 1 ~ 2
Antibacterial effect, result such as the following table 1：
The antibacterial effect of 1 shower cream of the present invention of table
It can be obtained by upper table 1, the good anti-bacterial effect of 1 ~ 3 shower cream of the embodiment of the present invention reaches the killing rate of staphylococcus aureus
99.85%, reach《Extraordinary bath agent》The requirement of antibiotic rate >=90% in standard, therefore shower cream of the present invention reaches antibacterial bath cream
Rank, the wherein sterilizing rate highest of embodiment 1 illustrates that 1 each component of embodiment and proportioning synergistic effect are most strong.Comparative example 1 is washed one's hair
Plant extracts is free of in bath lotion, 2 shower cream of comparative example only contains plant extracts, and sterilizing rate is compared to embodiment 1 ~ 3
Will be low, illustrating plant extracts of the present invention and Thymol and salicyl salicylate (salsalate), there are very strong synergistic effects, and three's compounding can
Play very strong antibacterial action.
Test example two：
The irritation of shower cream of the present invention is tested
According to《Cosmetics health specification》（Version in 2007）Skin irritation/corrosion test is to embodiment 1 and comparative example 3 ~ 4
Shower cream carries out dermoreaction scoring, and concrete operations are as follows：
1, experimental animal：Healthy white rabbit 12, female, 1.8 ~ 2.2kg, skin zero damage are divided into 3 groups, every group 4.
2, experimental procedure：
Experiment white rabbit back backbone diamond wool is cut for 24 hours before 2.1 experiments, does not damage epidermis, unhairing range or so respectively for 3cm ×
3cm。
2.2 take tested material（That is 3 ~ 4 shower cream of embodiment 1 and comparative example）0.5g is coated directly on skin, then with two layers
Gauze（2.5cm×2.5cm）It is covered with one layer of glassine paper, then fixed with nonirritant adhesive plaster and bandage.Other side skin
As a contrast.Using blocking test, application 2h.After the test residual tested material is removed with warm water.
Position dermoreaction is smeared in 2.3 1,24, the 48 and 72h observations after removing tested material, and it is anti-to carry out skin by table 2
Should score, overall merit is carried out with the average value of animal subject integral, according to for 24 hours, 48h and 72h respectively observe time point top
Mean value judges skin irritatin intensity by table 3.
2 skin wound repair of table scores
| Dermoreaction | Integral |
| Erythema and eschar are formed | |
| Without erythema | 0 |
| Slight erythema（It is visible reluctantly） | 2 |
| Apparent erythema | 1 |
| Moderate ~ severe erythema | 2 |
| Severe erythema（Aubergine）It is formed to slight eschar | 3 |
| Oedema is formed | |
| Without oedema | 0 |
| Slight oedema（It is visible reluctantly） | 1 |
| Mild edema（Cutaneous protuberance is clearly outlined） | 1 |
| Intermediate edema（Cutaneous protuberance 1mm） | 2 |
| Severe edema（Cutaneous protuberance is more than 1mm, and range expands） | 3 |
| Top | 8 |
3 skin irritatin strength grading of table
| Integral mean value | Intensity |
| 0~<0.5 | It is nonirritant |
| 0.5~<2.0 | Subexcite |
| 2.0~<6.0 | Moderate stimulation |
| 6.0~8.0 | Strong and stimulating |
3, experimental result：It see the table below 4
The irritation test result of 4 shower cream of the present invention of table
It can be obtained by upper table 4, shower cream of the present invention works as to no skin irritation and lacks -6 caprylate of polyglycereol in system, gathers
When -4 certain herbaceous plants with big flowers acid esters of glycerine and -3 cocounut oil acid esters of polyglycereol（That is comparative example 3）, the irritation enhancing of shower cream, to skin generation moderate
Stimulation, causes erythema and oedema；And when lacking squalene in system（That is comparative example 4）, the irritation of shower cream also has
Slight enhancing illustrates the polyglycereol fat of -6 caprylate of polyglycereol, -4 certain herbaceous plants with big flowers acid esters of polyglycereol and -3 cocounut oil acid esters of polyglycereol compounding
Acid ester composite is indispensable in the technical solution of the present invention, and the collaboration of three's ingredient can be substantially reduced formula irritation, then coordinate
Squalene further reduces irritation of the system to skin.
Test example three:
The moistening effect of shower cream of the present invention is tested
1, trial target：Shower cream prepared by the embodiment of the present invention 1 ~ 3 and comparative example 3.
2, tested crowd
Number：32 people
Age：Between 24 ~ 30 years old
Gender：20 people of female, male 12 people
Grouping：It is divided into 4 groups, every group of 5 people of female, male 3 people.
Health status：Subjects skin's health, no skin disease allergies meet subject and volunteer inclusion criteria.
3, test method：In 5 square centimeters of position of volunteer's right hand inner forearm, test zone is drawn, is surveyed with moisture
The moisture content of skin after instrument is tested the water content of the preceding skin of washing and washed 2 hours respectively is tried, it is increased to calculate water content
Percentage %.
4, test result：It see the table below 5.
The moistening effect test result of 5 shower cream of the present invention of table
| Project | Moisture content of skin before washing | Moisture content of skin after washing 2 hours | Water content increases percentage % |
| Embodiment 1 | 35.24 | 43.91 | 24.64 |
| Embodiment 2 | 36.88 | 45.51 | 23.52 |
| Embodiment 3 | 35.80 | 44.12 | 23.14 |
| Comparative example 3 | 35.57 | 40.22 | 13.14 |
It can be obtained by upper table 5, the moistening effect of shower cream of the present invention is good, and moisture content of skin increases percentage and is more than after washing 2 hours
23%, it is especially best with the moistening effect of embodiment 1, reach 24.6%, each component synergistic effect is most strong；Simultaneously embodiment 1 ~ 3 with
Comparative example 3 is compared, and water content increases percentage and improves about 10%, illustrates -6 caprylate of polyglycereol of the present invention, polyglycereol -4 certain herbaceous plants with big flowers acid
Ester and the polyglyceryl fatty acid ester composition of -3 cocounut oil acid esters of polyglycereol compounding can not only reduce the irritation of system, moreover it is possible to effectively
Ground improves the performance of keeping humidity of system, alleviates skin tight feeling after taking a shower.
It the above is only the preferred embodiment of the present invention, it is noted that above-mentioned preferred embodiment is not construed as pair
The limitation of the present invention, protection scope of the present invention should be subject to claim limited range.For the art
For those of ordinary skill, without departing from the spirit and scope of the present invention, several improvements and modifications can also be made, these change
Protection scope of the present invention is also should be regarded as into retouching.
Claims (5)
1. a kind of shower cream includes the component of following weight percent meter：Thymol 0.1 ~ 0.5%, ethyl alcohol 0.2 ~ 1%, the third two
Alcohol 0.5 ~ 3.5%, lauric acid 2 ~ 8%, myristic acid 4 ~ 9%, palmitic acid 2 ~ 8%, potassium hydroxide 1.5 ~ 6%, glycol distearate
1 ~ 2%, sulfosuccinic acid ethylhexyl sodium 1 ~ 5%, Cocoamidopropyl betaine 3 ~ 7%, sodium cocoyl glycinate 1 ~ 5%, poly-
Quaternary ammonium salt -7 0.1 ~ 1.5%, polyglyceryl fatty acid ester composition 0.3 ~ 3%, tetrasodium ethylenediamine tetraacetate 0.1 ~ 1%, sodium chloride 0.2
~ 1.5%, essence 0.2 ~ 1%, water 30 ~ 80%, which is characterized in that further include salicyl salicylate (salsalate) 0.1 ~ 0.5%, acetic acid 0.1 ~ 1%, squalene
0.1 ~ 1%, vitamin B 0.3 ~ 1%, vitamin C 0.1 ~ 1% and preservative 0.1 ~ 0.3%.
2. shower cream as described in claim 1, which is characterized in that the preservative is Phenoxyethanol.
3. shower cream as described in claim 1, which is characterized in that the polyglyceryl fatty acid ester composition includes polyglycereol -6
- 4 certain herbaceous plants with big flowers acid esters of caprylate and polyglycereol.
4. shower cream as described in claim 1, which is characterized in that the shower cream further includes plant extracts 0.2 ~ 2.0%.
5. a kind of method preparing the shower cream as described in claim 1 ~ 4 is any, which is characterized in that include the following steps：
（1）Thymol, salicyl salicylate (salsalate) are added to be dissolved to transparent in ethyl alcohol, add plant extracts, propylene glycol stir to
It is fully transparent, it is prepared into bactericidal composition, it is spare；
（2）Potassium hydroxide is added into the water of component weight 45 ~ 55% to dissolve and stir evenly, lauric acid, Pork and beans is then added
Cool acid, palmitic acid ethylene glycol distearyl acid, sulfosuccinic acid ethylhexyl sodium, are persistently stirred and heated to 75 DEG C, insulation reaction
25~35min；
（3）After the completion of reaction, Cocoamidopropyl betaine, polyglyceryl fatty acid ester composition is added, and stir evenly, system
55 DEG C are cooled to, sodium cocoyl glycinate, polyquaternium -7 is added, and stir evenly；
（4）System is cooled to 35 DEG C, tetrasodium ethylenediamine tetraacetate, sodium chloride, acetic acid, essence is then added into system, stirring is extremely
It is completely dissolved；
（5）Enter step（1）Bactericidal composition, stir evenly, be eventually adding preservative, water, squalene, vitamin B and Wei Sheng
Plain C, stirs evenly.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810273412.0A CN108451810A (en) | 2018-03-29 | 2018-03-29 | A kind of shower cream and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810273412.0A CN108451810A (en) | 2018-03-29 | 2018-03-29 | A kind of shower cream and preparation method thereof |
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| Publication Number | Publication Date |
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| CN108451810A true CN108451810A (en) | 2018-08-28 |
Family
ID=63238189
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810273412.0A Withdrawn CN108451810A (en) | 2018-03-29 | 2018-03-29 | A kind of shower cream and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108294990A (en) * | 2018-03-29 | 2018-07-20 | 李皆延 | Shower cream and preparation method thereof |
| CN113081911A (en) * | 2021-03-09 | 2021-07-09 | 深圳职业技术学院 | Itching-relieving shower gel, preparation method thereof and shower bottle for containing itching-relieving shower gel |
| CN114403143A (en) * | 2022-01-21 | 2022-04-29 | 广州蓝月亮实业有限公司 | Anti-freezing quaternary ammonium salt composition and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1135174A (en) * | 1993-06-18 | 1996-11-06 | 普罗克特和甘保尔公司 | Personal cleansing system comprising a polymeric diamond-mesh bath sponge and a liquid cleanser with moisturizer |
| JP2009029739A (en) * | 2007-07-26 | 2009-02-12 | Shiseido Co Ltd | Bath agent composition |
| CN104800123A (en) * | 2015-04-28 | 2015-07-29 | 威莱(广州)日用品有限公司 | Antibacterial soap-based shower gel and preparation method thereof |
-
2018
- 2018-03-29 CN CN201810273412.0A patent/CN108451810A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1135174A (en) * | 1993-06-18 | 1996-11-06 | 普罗克特和甘保尔公司 | Personal cleansing system comprising a polymeric diamond-mesh bath sponge and a liquid cleanser with moisturizer |
| JP2009029739A (en) * | 2007-07-26 | 2009-02-12 | Shiseido Co Ltd | Bath agent composition |
| CN104800123A (en) * | 2015-04-28 | 2015-07-29 | 威莱(广州)日用品有限公司 | Antibacterial soap-based shower gel and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108294990A (en) * | 2018-03-29 | 2018-07-20 | 李皆延 | Shower cream and preparation method thereof |
| CN113081911A (en) * | 2021-03-09 | 2021-07-09 | 深圳职业技术学院 | Itching-relieving shower gel, preparation method thereof and shower bottle for containing itching-relieving shower gel |
| CN114403143A (en) * | 2022-01-21 | 2022-04-29 | 广州蓝月亮实业有限公司 | Anti-freezing quaternary ammonium salt composition and preparation method and application thereof |
| CN114403143B (en) * | 2022-01-21 | 2024-07-12 | 广州蓝月亮实业有限公司 | Anti-freezing quaternary ammonium salt composition and preparation method and application thereof |
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