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CN108404097A - A kind of swelling and pain relieving ointment and preparation method thereof - Google Patents

A kind of swelling and pain relieving ointment and preparation method thereof Download PDF

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Publication number
CN108404097A
CN108404097A CN201810527135.1A CN201810527135A CN108404097A CN 108404097 A CN108404097 A CN 108404097A CN 201810527135 A CN201810527135 A CN 201810527135A CN 108404097 A CN108404097 A CN 108404097A
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Prior art keywords
mass parts
swelling
ointment
pain relieving
mass
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CN201810527135.1A
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Chinese (zh)
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张爱琴
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Individual
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/69—Polygalaceae (Milkwort family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714—Aconitum (monkshood)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884—Arisaema, e.g. Jack in the pulpit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0041—Mammary glands, e.g. breasts, udder; Intramammary administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of swelling and pain relieving ointment and preparation method thereof.The present invention after mixing 7~9 mass parts frankincenses, 7~9 mass parts myrrhs, 5~7 mass parts rhizoma arisaematis, 6~8 mass parts RADIX ACONITI LATERALIS PREPARATAs, 4~6 mass parts Chinese cassia trees, 5~7 mass parts semen brassicaes, 6~8 mass parts raw ephedras, 9~11 mass parts baked gingers, 7~9 mass parts Radix Polygalaes by breaking into powder, 120 mesh sieve is crossed, 1 is pressed with vaseline：4 mix well to obtain swelling and pain relieving ointment.The preparation method of swelling and pain relieving ointment of the present invention is more simple, and required medicament categories are less, and need not put into greatly can be produced in batches；Prepared swelling and pain relieving ointment has effects that warming and activating meridian, reducing phlegm and resolving masses, promoting blood circulation and removing blood stasis, swelling and pain relieving, it can be clinically used for the treatment of breast pain, the proliferation of mammary gland, galactoncus, mammary gland inflammatory masses and masses caused by cold obstruction causing qi stagnation, phlegm resistance blood stasis, it is significant in efficacy, adverse reaction is rare, have no toxic side effect.

Description

A kind of swelling and pain relieving ointment and preparation method thereof
Technical field
Caused by the invention belongs to technical field of Chinese medicine, more particularly to one kind is for treating cold obstruction causing qi stagnation, phlegm resistance blood stasis The swelling and pain relieving ointment of breast pain, the proliferation of mammary gland, galactoncus, mammary gland inflammatory masses and masses.
Background technology
Breast pain, the proliferation of mammary gland, galactoncus, mammary gland inflammatory masses and masses are to face caused by cold obstruction causing qi stagnation, phlegm resistance blood stasis Bed common disease, frequently-occurring disease.The disease clinical treatment period is long, currently, the Chinese medicine preparation for treating such disease is more, but is mostly for oral administration Medicine, medication time is long, in addition stimulation of the Chinese medicine to gastrointestinal tract, and many patients are not resistant to, and mental burden is brought to patient.The medicine Cream is prepared simply, and topical application is absorbed by skin, and drug is made not destroyed by the first pass effect of stomach and intestine to digestive juice and liver, The stimulation to gastrointestinal tract is avoided simultaneously, reduces toxic side effect, is infiltrated in local concentration, is improved drug to local target tissue Effect, improve curative effect.
Invention content
The purpose of the present invention is to provide a kind of swelling and pain relieving ointment, it is intended to solve the prior art in above-mentioned background technology Shortcoming.
The invention is realized in this way a kind of swelling and pain relieving ointment, which includes each component in parts by mass：7 ~9 mass parts frankincenses, 7~9 mass parts myrrhs, 5~7 mass parts rhizoma arisaematis, 6~8 mass parts RADIX ACONITI LATERALIS PREPARATAs, 4~6 mass parts meat Osmanthus, 5~7 mass parts semen brassicaes, 6~8 mass parts raw ephedras, 9~11 mass parts baked gingers, 7~9 mass parts Radix Polygalaes.
Preferably, the ointment includes each component in parts by mass：8 mass parts frankincenses, 8 mass parts myrrhs, 6 mass Part rhizoma arisaematis, 7 mass parts RADIX ACONITI LATERALIS PREPARATAs, 5 mass parts Chinese cassia trees, 6 mass parts semen brassicaes, 7 mass parts raw ephedras, 10 mass parts baked gingers, 8 Mass parts Radix Polygalae.
In the present invention, frankincense, myrrh, Radix Polygalae be promoting blood circulation and removing blood stasis, swelling and pain relieving, RADIX ACONITI LATERALIS PREPARATA, Chinese cassia tree, baked ginger warming and activating meridian, Dissipating bind that Chinese ephedra, rhizoma arisaematis, semen brassicae, Radix Polygalae are warming cold phlegm, the formula ointment warming and activating meridian, reducing phlegm and resolving masses, it is promoting blood circulation and removing blood stasis, disappear Swollen analgesic has effects that protrusion.
The present invention further discloses the preparation method of above-mentioned swelling and pain relieving ointment, this method is：By frankincense, myrrh, day Southern Star, RADIX ACONITI LATERALIS PREPARATA, Chinese cassia tree, semen brassicae, raw ephedra, baked ginger, Radix Polygalae break into powder after being mixed by the mass parts, cross 120 mesh sieve, use Vaseline presses 1：4 ratios mix well to obtain.
Compared with the prior art the shortcomings that and deficiency, the invention has the advantages that：
(1) preparation method of swelling and pain relieving ointment of the present invention is more simple, and required medicament categories are less, need not throw greatly Entering can be produced in batches；
(2) swelling and pain relieving ointment of the present invention has effects that warming and activating meridian, reducing phlegm and resolving masses, promoting blood circulation and removing blood stasis, swelling and pain relieving, faces It can be used for breast pain, the proliferation of mammary gland, galactoncus, mammary gland inflammatory masses and masses caused by cold obstruction causing qi stagnation, phlegm resistance blood stasis on bed to control It treats, it is significant in efficacy, adverse reaction is rare, it has no toxic side effect.
Specific implementation mode
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.
Embodiment 1
By 8 grams of frankincenses, 8 grams of myrrhs, 6 grams of rhizoma arisaematis, 7 grams of RADIX ACONITI LATERALIS PREPARATAs, 5 grams of Chinese cassia trees, 6 grams of semen brassicaes, 7 grams of raw ephedras, 10 Powder is beaten in gram baked ginger, 8 grams of Radix Polygalaes mixing, 120 mesh sieve is crossed, with vaseline by 1：4 ratios mix well to obtain swelling and pain relieving ointment 1.
Embodiment 2
By 7 grams of frankincenses, 9 grams of myrrhs, 5 grams of rhizoma arisaematis, 8 grams of RADIX ACONITI LATERALIS PREPARATAs, 4 grams of Chinese cassia trees, 7 grams of semen brassicaes, 6 grams of raw ephedras, 11 Powder is beaten in gram baked ginger, 7 grams of Radix Polygalaes mixing, 120 mesh sieve is crossed, with vaseline by 1：4 ratios mix well to obtain swelling and pain relieving ointment 2.
Embodiment 3
By 9 grams of frankincenses, 7 grams of myrrhs, 7 grams of rhizoma arisaematis, 6 grams of RADIX ACONITI LATERALIS PREPARATAs, 6 grams of Chinese cassia trees, 5 grams of semen brassicaes, 8 grams of raw ephedras, 9 Powder is beaten in gram baked ginger, 9 grams of Radix Polygalaes mixing, 120 mesh sieve is crossed, with vaseline by 1：4 ratios mix well to obtain swelling and pain relieving ointment 1.
Comparative example 1
8 grams of frankincenses, 8 grams of myrrhs, 8 grams of Radix Polygalaes are mixed and beat powder, 120 mesh sieve is crossed, 1 is pressed with vaseline：4 ratios are mixed well To swelling and pain relieving ointment 4.
Comparative example 2
7 grams of RADIX ACONITI LATERALIS PREPARATAs, 5 grams of Chinese cassia trees, 10 grams of baked gingers are mixed and beat powder, 120 mesh sieve is crossed, 1 is pressed with vaseline：4 ratios are mixed well Obtain swelling and pain relieving ointment 5.
Comparative example 3
6 grams of rhizoma arisaematis, 6 grams of semen brassicaes, 7 grams of raw ephedras, 8 grams of Radix Polygalaes are mixed and beat powder, 120 mesh sieve is crossed, is pressed with vaseline 1：4 ratios mix well to obtain swelling and pain relieving ointment 6.
Effect example
The swelling and pain relieving ointment 1 of comparing embodiment 1 is with the swelling and pain relieving ointment 4~6 of comparative example 1~3 to cold solidifying Breast pain, the proliferation of mammary gland, galactoncus, mammary gland inflammatory masses and masses patient caused by the stagnation of the circulation of vital energy, phlegm resistance blood stasis carry out clinical comparison and control It treats.
Therapy：Swelling and pain relieving ointment is uniformly applied on gauze, about 2 mm of thickness, range is slightly larger than pain And lump area, it is pasted on affected part.
Treatment time：2 weeks as a treatment course, and 1~3 course for the treatment of is treated according to the state of an illness.
Therapeutic effect standard：
It is effective：Pain disappears, and tumor regression, ultrasonic examination lesion disappears substantially；
Effectively：Pain is substantially reduced, 1/2 or more tumor regression, and ultrasonic examination lesion range is reduced；
In vain：Pain does not mitigate, and lump is unchanged, and ultrasonic examination lesion range is without reduction.
Points for attention：If there are the allergic reactions such as skin erythema, stops using and observed after removing skin immediately, it is necessary When in time go to a doctor follow the doctor's advice.
Therapeutic effect is counted, as shown in table 1 below：
1 effect of table counts
Number Case load It is effective Effectively In vain
Ointment 1 500 450 50 0
Ointment 4 455 20 90 345
Ointment 5 420 10 84 326
Ointment 6 426 0 70 356
By upper table 1 it is found that the ointment 1 of the embodiment of the present invention 1 is to breast pain, breast caused by cold obstruction causing qi stagnation, phlegm resistance blood stasis Gland hyperplasia, galactoncus, the therapeutic effect of mammary gland inflammatory masses and masses be notable, and 4~ointment of ointment 6 of documents 1~3 is controlled Therapeutic effect but differs greatly.The drug effect of Chinese medicine itself can be absorbed to a certain extent by human body, still, Chinese medicine each group drug dispensing The cooperation of effect could make final therapeutic effect perform to optimum state.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention All any modification, equivalent and improvement etc., should all be included in the protection scope of the present invention made by within refreshing and principle.

Claims (3)

1. a kind of swelling and pain relieving ointment, which is characterized in that the ointment includes each component in parts by mass：7~9 mass parts breast Perfume, 7~9 mass parts myrrhs, 5~7 mass parts rhizoma arisaematis, 6~8 mass parts RADIX ACONITI LATERALIS PREPARATAs, 4~6 mass parts Chinese cassia trees, 5~7 mass parts Semen brassicae, 6~8 mass parts raw ephedras, 9~11 mass parts baked gingers, 7~9 mass parts Radix Polygalaes.
2. ointment as described in claim 1, which is characterized in that the ointment includes each component in parts by mass：8 mass Part frankincense, 8 mass parts myrrhs, 6 mass parts rhizoma arisaematis, 7 mass parts RADIX ACONITI LATERALIS PREPARATAs, 5 mass parts Chinese cassia trees, 6 mass parts semen brassicaes, 7 matter Measure part raw ephedra, 10 mass parts baked gingers, 8 mass parts Radix Polygalaes.
3. the preparation method of ointment as claimed in claim 1 or 2, which is characterized in that this method is：By frankincense, myrrh, Tian Nan Star, RADIX ACONITI LATERALIS PREPARATA, Chinese cassia tree, semen brassicae, raw ephedra, baked ginger, Radix Polygalae break into powder after being mixed by the mass parts, cross 120 mesh sieve, and use is all Intellectual circle presses 1：4 mix well to obtain.
CN201810527135.1A 2018-05-29 2018-05-29 A kind of swelling and pain relieving ointment and preparation method thereof Pending CN108404097A (en)

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Application Number Priority Date Filing Date Title
CN201810527135.1A CN108404097A (en) 2018-05-29 2018-05-29 A kind of swelling and pain relieving ointment and preparation method thereof

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Publication Number Publication Date
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109224042A (en) * 2018-09-03 2019-01-18 张董晓 A kind of Chinese medicine composition and its preparation for treating cyclomastopathy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109224042A (en) * 2018-09-03 2019-01-18 张董晓 A kind of Chinese medicine composition and its preparation for treating cyclomastopathy

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Application publication date: 20180817

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