CN108392173A - Multispectral fundus imaging equipment - Google Patents

Abstract

In the multi-spectral fundus imaging device provided by the present invention, the divergent light emitted by the light source forms a parallel beam through a collimating mirror; the parallel beam is incident on a cylindrical lens and focused to form a line beam, and the line beam is transmitted through a beam splitter and then enters a scanning galvanometer for scanning The galvanometer changes the reflection angle of the incident line beam to form a scanning beam. The scanning beam passes through the first lighting lens and the second lighting lens in turn, then focuses on the pupil and reaches the fundus; the imaging beam reflected by the fundus passes through the second lighting lens, After the first illumination lens and the scanning galvanometer enter the beam splitter, the beam splitter reflects the incident imaging beam to the imaging lens and focuses it on the dispersion unit through the imaging lens. After passing through the dispersion unit, the imaging beam is dispersed into different angles and passed through the dispersion unit The detection unit detects, and the detection unit converts the detected optical signal into an electrical signal; the circuit control module acquires the electrical signal and converts the electrical signal into an image signal and outputs it to the display module for display, which has a compact structure and is easy to operate.

Description

Multispectral fundus imaging equipment

technical field

The invention relates to a multispectral imaging technology belonging to applied optics, in particular to a multispectral fundus imaging device.

Background technique

In recent years, since confocal technology can use slits or small holes to filter out stray light in non-imaging planes, greatly improving imaging resolution, and confocal has the advantage of non-invasive inspection, it has become more and more popular in ophthalmic imaging. The traditional point-scanning confocal uses two vibrating mirrors to scan at the same time, so that the light source illuminates each point of the object to be measured, and through its reflected light or fluorescence imaging, when the size of the object to be measured is larger, the time required for one image to complete the scan The longer it is, the higher the scanning speed requirement for the galvanometer becomes. The line-scanning confocal imaging developed on this basis uses a one-dimensional scanning line beam instead of point beam illumination. The resolution of this method is lower than that of point confocal imaging, but the system is simpler, and the detection sensitivity is high, and the imaging frame rate is high. It is more advantageous than the previous method.

Fundus imaging is a widely used diagnostic item in ophthalmology. Fundus blood vessels are the only blood vessels that can be directly observed through the body surface. Through the observation of fundus images, doctors can not only diagnose fundus lesions, but also judge other systemic diseases, such as cerebral infarction, cerebral hemorrhage, cerebral arteriosclerosis, brain tumors, diabetes, kidney disease, hypertension, etc. However, traditional fundus examination instruments are generally desktop, including complex lighting systems and observation systems, with huge volume and complex system structure; some instruments need to install special software on the computer before they can be used, and the machine itself does not have image storage function. Can't even work independently without a computer. If a fundus image is needed, the patient needs to go to the instrument to take a fundus picture, which is extremely inconvenient for special patients, especially bedridden patients in hospitals, or patients in edge mountainous areas. At the same time, the single-wavelength fundus imaging technology can no longer meet the needs of ophthalmology diagnosis. Therefore, a multi-spectral fundus imaging device is urgently needed.

Contents of the invention

In view of this, it is necessary to provide a multi-spectral fundus imaging device, which aims to solve the complex structure of the fundus imaging device provided in the prior art and cannot meet the needs of ophthalmic diagnosis.

To achieve the above object, the present invention adopts the following technical solutions:

On the one hand, the multispectral fundus imaging device provided by the present invention includes an optical imaging component, a circuit control module, and a display module electrically connected to the circuit control module;

The optical imaging assembly includes a light source module, an illumination module, and an imaging module; the light source module includes a light source and a collimating mirror; the illumination module includes a cylindrical lens, a beam splitter, a scanning vibrating mirror, and an illumination lens group, and the illumination lens The group includes a first illumination lens and a second illumination lens, and the second illumination lens can reciprocate along its central axis; the imaging module includes an imaging lens, a dispersion unit and a detection unit;

The circuit control module is electrically connected to the scanning vibrating mirror and the detection unit, and the circuit controlling module is used to control the rotation speed and rotation angle of the scanning vibrating mirror;

The divergent light emitted by the light source forms a parallel beam through the collimating mirror; the parallel beam is incident on the cylindrical lens and focused to form a line beam, and the line beam is transmitted through the beam splitter and enters the scanning A vibrating mirror, the scanning vibrating mirror changes the reflection angle of the incident line beam to form a scanning beam, and the scanning beam sequentially passes through the first lighting lens and the second lighting lens, then focuses on the pupil and reaches the fundus;

The imaging beam reflected by the fundus then enters the beam splitter after passing through the second illumination lens, the first illumination lens, and the scanning galvanometer in sequence, and the beam splitter reflects the incident imaging beam to the imaging beam. The imaging lens is focused on the dispersion unit through the imaging lens, and the imaging light beam is dispersed into different angles by the dispersion unit and detected by the detection unit, and the detection unit converts the detected optical signal into an electrical signal Signal;

The circuit control module acquires the electrical signal and converts the electrical signal into an image signal and outputs it to the display module for display.

In some preferred embodiments, the light source includes a broadband white light source or a hybrid light source obtained by coupling light emitted by multiple single-wavelength light sources, and the broadband white light source includes a white light emitting diode, a white light superluminescent diode, a superradiant laser or halogen lamps.

In some preferred embodiments, the illumination lens group further includes a guide rail, the extension direction of the guide rail is consistent with the central axis direction of the first illumination lens and the second illumination lens, and the first illumination lens and the second illumination lens The lighting lens is slidably arranged on the guide rail.

In some preferred embodiments, the first lighting lens is a lens, and the second lighting lens is a front mirror.

In some preferred embodiments, the dispersion unit is a 300 lp/mm broadband diffraction light beam, and the detection unit is an area array CCD.

In some preferred embodiments, the display module includes an LED display, an LCD display or an AMOLED display.

In some preferred embodiments, a housing for fixing the display module is also included.

In some preferred embodiments, an adjustment module is fixed on the housing, and the adjustment module is used to adjust the position of the illumination lens group relative to human eyes.

In some preferred embodiments, the adjustment module includes an adjustment gear and an adjustment screw. By adjusting the adjustment gear and the adjustment screw, the movement of the first lighting lens and the second lighting lens along the slide rail is controlled. .

In some preferred embodiments, an interface module is also fixed on the housing, the interface module includes a light source interface and a data interface, the optical path interface is used to connect the light source to the optical path, and the data interface is used to In order to transmit the image signal to the display module for display or storage, the interface module is used to adjust the position of the illumination lens group relative to human eyes.

The present invention adopts above-mentioned technical scheme, can realize following beneficial effect:

The multi-spectral fundus imaging device provided by the present invention includes an optical imaging assembly, a circuit control module and a display module, the optical imaging assembly includes a light source module, an illumination module and an imaging module; the light source module includes a light source and a collimating mirror; The illumination module includes a cylindrical lens, a beam splitter, a scanning galvanometer, and an illumination lens group, the illumination lens group includes a first illumination lens and a second illumination lens, and the imaging module includes an imaging lens, a dispersion unit and a detection unit; The divergent light emitted by the light source passes through the collimating mirror to form a parallel beam; the parallel beam is incident on the cylindrical lens and focused to form a line beam, and the line beam is transmitted through the beam splitter and enters the scanning galvanometer , the scanning galvanometer changes the reflection angle of the incident line beam to form a scanning beam, and the scanning beam sequentially passes through the first lighting lens and the second lighting lens and then focuses on the pupil and reaches the fundus; The imaging beam then passes through the second illumination lens, the first illumination lens, and the scanning galvanometer in sequence and enters the beam splitter, and the beam splitter reflects the incident imaging beam to the imaging lens and passes through the beam splitter. The imaging lens is focused at the dispersion unit, the imaging light beam is dispersed into different angles by the dispersion unit and detected by the detection unit, and the detection unit converts the detected optical signal into an electrical signal; The circuit control module acquires the electrical signal and converts the electrical signal into an image signal and outputs it to the display module for display. The multi-spectral fundus imaging device provided by the present invention has a compact structure, simple operation, and portability; at the same time, it adopts multiple Wavelength imaging, one imaging can meet the needs of various inspections; and the line scanning confocal imaging method is adopted, with high imaging resolution and fast imaging speed.

In addition, the multi-spectral fundus imaging device provided by the present invention has adjustable diopters to meet the needs of fundus imaging for people with different visions; the collected images can be displayed in real time, and can also be connected to the host computer to realize image transmission, display and storage .

Description of drawings

FIG. 1 is a schematic structural diagram of a multispectral fundus imaging device provided in this embodiment.

Fig. 2a is a schematic diagram of the horizontal optical path of the multispectral fundus imaging device provided in this embodiment.

Fig. 2b is a schematic diagram of the optical path in the vertical direction of the multispectral fundus imaging device provided by this embodiment.

Fig. 3 is a control schematic diagram of a circuit control module of a multispectral fundus imaging device provided by an embodiment of the present invention.

Detailed ways

In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

1 and 2(a), 2(b), the multispectral fundus imaging device 10 provided by the embodiment of the present invention includes an optical imaging component 110, a circuit control module 120 and is electrically connected to the circuit control module 120 The display module 130. in:

The optical imaging assembly 110 includes a light source module 111 , an illumination module 112 and an imaging module 113 .

The light source module 111 includes a light source 1111 and a collimating mirror 1112 .

In some preferred embodiments, the light source 1111 includes a broadband white light source or a mixed light source obtained by coupling light emitted by multiple single-wavelength light sources. Radiation lasers or halogen lamps.

It can be understood that the light beam emitted by the light source 1111 is transformed into a parallel light beam by the collimating mirror 1112 .

The illumination module 112 includes a cylindrical lens 1121 , a beam splitter 1122 , a scanning galvanometer 1123 and an illumination lens group 1124 .

In some preferred embodiments, the cylindrical lens 1121 is a double cemented cylindrical lens.

In some preferred embodiments, the transmittance and reflectance ratio of the beam splitter 1122 to the light beam is 10/90.

In some preferred embodiments, the scanning module 1123 is a high-speed scanning galvanometer.

It can be understood that the rotation speed and rotation angle of the scanning galvanometer 1123 are controlled by the circuit control module 120 , so that the reflection angle of the incident light beam can be changed.

The illumination lens group 1124 includes a first illumination lens a and a second illumination lens b, and the second illumination lens b can reciprocate along its central axis.

In some preferred embodiments, the first lighting lens is a lens with f=50mm, and the second lighting lens is a VOLK78D front mirror.

In some preferred embodiments, the illumination lens group 1124 further includes a guide rail c, the extension direction of the guide rail c is consistent with the central axis direction of the first illumination lens a and the second illumination lens b, and the first illumination lens a An illumination lens a and a second illumination lens b are slidably arranged on the guide rail c.

In some preferred embodiments, the guide rail c is also provided with an adjustment module, the adjustment module includes an adjustment gear d and an adjustment screw e, and by adjusting the adjustment gear d and the adjustment screw e, the first lighting lens is controlled a and the second lighting lens b move along the slide rail c to meet the fundus imaging needs of people with different visions.

The imaging module 113 includes an imaging lens 1131 , a dispersion unit 1132 and a detection unit 1133 .

In some preferred embodiments, the imaging lens 1131 is a doublet convex lens, the dispersion module 1132 is a broadband diffraction beam of 300 lp/mm, and the detection module 1133 is an area array CCD, and the detection module collects Optical signals are converted into electrical signals.

The multispectral fundus imaging device provided by the present invention has the following working principles:

The divergent light emitted by the light source 1111 forms a parallel beam through the collimating mirror 1112; the parallel beam is incident on the cylindrical lens 1121 and focused to form a line beam, and the line beam is transmitted through the beam splitter 1122 and then incident Entering the scanning galvanometer 1123, the scanning galvanometer 1123 changes the reflection angle of the incident line beam to form a scanning beam, and the scanning beam sequentially passes through the first illumination lens a and the second illumination lens b and then focuses on Behind the pupil and reaches the fundus m;

The imaging beam reflected by the fundus passes through the second illumination lens b, the first illumination lens a, and the scanning galvanometer 1123 in sequence, and then enters the beam splitter 1122, and the beam splitter 1122 converts the incident imaging beam Reflected to the imaging lens 1131 and focused on the dispersion unit 1132 through the imaging lens 1131, the imaging beam is dispersed into different angles after passing through the dispersion unit 1132 and detected by the detection unit 1133. The detection unit 1133 converts the detected optical signal into an electrical signal; please refer to FIG. 2(a) and FIG. 2(b), the light is focused in the vertical direction in front of the dispersion unit 1132, and the horizontal direction is parallel light, forming a line; After passing through the dispersion unit 1132, the light of different wavelengths is separated and reaches the photosensitive surface of the detection unit 1133

The circuit control module 120 acquires the electrical signal and converts the electrical signal into an image signal and outputs it to the display module 130 for display.

Please refer to FIG. 3 , which is a control diagram of the circuit control module 120 of the multispectral fundus imaging device according to an embodiment of the present invention.

The circuit control module 120 is electrically connected to the scanning module 1123, and is used to control the rotation speed and rotation angle of the scanning module 1123, so that the line beam performs one-dimensional scanning to image the fundus.

The circuit control module 120 is also electrically connected to the detection unit 1133, for receiving the electrical signal converted from the optical signal collected by the detection unit 1133, and converting the electrical signal into an image signal for real-time display by the display module 130, Or transfer to a computer.

The circuit control module 120 can also control the adjustment module. When the image displayed by the display module 130 is not clear, the circuit control module 120 controls the adjustment module to adjust the relative position of the illumination lens group 1124 to meet the needs of fundus imaging with different diopters.

The circuit control module 120 is also electrically connected to the button, and the user can set various parameters of the device through the button, such as the intensity of the lighting source energy, video and photo mode, picture browsing mode, lighting mode, time setting, date setting, etc. .

In some preferred embodiments, the display module 130 includes an LED display, an LCD display or an AMOLED display.

In some preferred embodiments, the multispectral fundus imaging device 100 further includes a housing (not shown) for fixing the display module 130 .

In some preferred embodiments, the housing is also fixed with an interface module 150, the interface module 150 includes a light source interface 151 and a data interface 152, and the light source interface 151 is used to connect the light source 1111 into the optical path , the data interface 152 is used to transmit the image signal to the display module 130 for display or storage.

It can be understood that the multi-spectral fundus imaging device in the embodiment of the present invention, in practical application, first brings the multi-spectral fundus imaging device close to the human eye, and images the fundus of the human eye through the optical imaging module, and the obtained image is processed by the circuit control module 120 and then displayed On the display module 130 or through the data interface 152, the image is transmitted to the computer for display. If the image is not clear enough, the position of the imaging module 113 and the illumination lens group 1124 relative to the human eye can be adjusted by adjusting the adjustment module on the casing, so that the fundus image After the fundus image can be clearly displayed and a better effect is obtained, the image is saved on the computer through the control button 153 .

The multi-spectral fundus imaging device provided by the present invention has compact structure, simple operation, and is easy to carry; at the same time, it adopts multi-wavelength imaging, and one imaging can meet various inspection needs; high speed.

In addition, the multi-spectral fundus imaging device provided by the present invention has adjustable diopters to meet the needs of fundus imaging for people with different visions; the collected images can be displayed in real time, and can also be connected to the host computer to realize image transmission, display and storage .

The above descriptions are only preferred embodiments of the present invention, and are not intended to limit the present invention. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present invention shall be included in the protection of the present invention. within range.

Claims (9)

1. a kind of multispectral fundus imaging equipment, which is characterized in that including optical imaging assemblies, circuit control module and with it is described The display module that circuit control module is electrically connected；

The optical imaging assemblies include light source module, lighting module and image-forming module；The light source module includes light source and standard Straight mirror；The lighting module includes cylindrical lens, spectroscope, scanning galvanometer and illuminating lens group, and the illuminating lens group includes First illuminating lens and the second illuminating lens, second illuminating lens can be moved back and forth along center axis；The imaging mould Block includes imaging len, dispersion element and probe unit；

The circuit control module is electrically connected the scanning galvanometer and the probe unit, and the circuit control module is for controlling Make the velocity of rotation and rotational angle of the scanning galvanometer；

The diverging light of the light source outgoing forms collimated light beam through the collimating mirror；The parallel beam incident is saturating to the cylinder Mirror forms Line beam after focusing, the Line beam is incident after spectroscope transmission to enter the scanning galvanometer, the scanning The reflection angle that galvanometer changes the incident Line beam forms scanning light beam, and the scanning light beam is illuminated through described first successively It is focused on after pupil after lens, the second illuminating lens and reaches eyeground；

Imaging beam through fundus reflex shakes through second illuminating lens, first illuminating lens, the scanning successively again It is incident after mirror to enter the spectroscope, the spectroscope by incident imaging beam reflex to the imaging len and through it is described at At the dispersion element, the imaging beam is separated into different angles after the dispersion element and through institute picture lens focus Probe unit detection is stated, the probe unit converts the optical signal of detection to electric signal；

The circuit control module obtains the electric signal and converts the electric signal to picture signal and exports to the display Module is shown.

2. multispectral fundus imaging equipment according to claim 1, which is characterized in that the light source includes broadband white light source Or the coupled obtained mixing light source of light sent out by multiple single wavelength light sources, the broadband white light source includes white-light emitting two Pole pipe, white light superluminescent diode, super radiation laser or halogen lamp.

3. multispectral fundus imaging equipment according to claim 1, which is characterized in that the illuminating lens group further includes leading Rail, the extending direction of the guide rail is consistent with first illuminating lens and the central axial direction of the second illuminating lens, described First illuminating lens and the second illuminating lens are slidably disposed on the guide rail.

4. multispectral fundus imaging equipment according to claim 1, which is characterized in that the dispersion element is broadband diffraction Light coral, the probe unit are face battle array photosensitive unit.

5. multispectral fundus imaging equipment according to claim 1, which is characterized in that the display module includes LED aobvious Display screen, LCD display or AMOLED display screens.

6. multispectral fundus imaging equipment according to claim 1, which is characterized in that further include the fixed display module Shell.

7. multispectral fundus imaging equipment according to claim 6, which is characterized in that be further fixed on adjusting on the shell Module, the adjustment module is for adjusting position of the illuminating lens group with respect to human eye.

8. multispectral fundus imaging equipment according to claim 7, which is characterized in that the adjustment module includes adjusting tooth Wheel and adjusting screw rod, by adjusting the adjustment gear and the adjusting screw rod, to control first illuminating lens and Second illuminating lens is moved along the sliding rail.

9. multispectral fundus imaging equipment according to claim 1, which is characterized in that be further fixed on interface on the shell Module, the interface module include light source interface and data-interface, and the optical-path interface is used to that light source to be accessed light path by described, The data-interface is for showing or storing described image signal transmission to the display module.