CN107801995A - A kind of asparagus composition for preventing and nursing one's health menopause symptom and its application - Google Patents
A kind of asparagus composition for preventing and nursing one's health menopause symptom and its application Download PDFInfo
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention relates to a kind of asparagus composition for preventing and nursing one's health menopause symptom,Belong to food technology field,The asparagus composition includes 240 300 parts of Germinatus Phragmitis extracts according to mass ratio compatibility,16 24 parts of casein active peptides,16 24 parts of purple sweetpotato extracts,30 40 parts of hippophae rhamnoides,18 30 parts of Rhizoma Polygonati extracts,10 20 parts of perilla leaf extracts,6 10 parts of gamma aminobutyric acids and 48 parts of theanine,The asparagus composition also can apply to prevent and nurse one's health the food of menopause symptom,In the preparation of health food or medicine,Composition in the present invention can improve human body oxidation resistance,It is stable to adjust vegetative nerve,It is horizontal to improve neurotransmitter secretion,Hypotensive,Reducing blood lipid,In the case where not adding any exogenous hormones or estrogen-like composition,Fundamentally nurse one's health global tissue function,Delay climacteric,Development and the symptom for improving climacteric metancholia.
Description
Technical field
The invention belongs to food technology field, and in particular to it is a kind of prevent and conditioning menopause symptom asparagus composition and
It is applied.
Background technology
Climacteric metancholia (also known as perimenopausal syndrome) refer to postmenopausal women it is front and rear due to ovarian function gradually fails,
Estrogen reduces a series of spirit such as caused vegetative nerve functional disturbance, atrophy of genital system and Body reactions, often with kind anger
Easily cry, warm sweating, be dysphoria in chestpalms-soles, dizziness and tinnitus, forgetful, palpitaition egersis, paramenia and arthralgia etc. is mainly face
Bed feature, is more common in 46~60 years old women, wherein menopause symptom occurs in 2/3rds perimenopausal women.With society
Increasingly fierce and people's physiology of competition, psychological pressure continue to increase, and the progress of the aging process in the whole world, climacteric are comprehensive
It is in continuous ascendant trend to close disease whole world incidence, and age of onset is gradually shifting to an earlier date.Global climacteric women there are about 4.5 hundred million,
Therein 28% in China, and the women that China is in stage climacteric is about 1.3 hundred million, wherein there is menopause symptom clinical manifestation
Up to 100,000,000.Not the reason for appearance of menopause symptom is not single, but it is relevant with many factors such as society, family and spirit.
Prior art mainly has general treatment, hormone replacement therapy, plant are female to swash for the treatment method of menopause symptom
The methods of extract for treating, Chinese medicine.The general treatment such as psychotherapy and behaviour therapy method safety, adverse reaction is small, takes effect
It hurry up, but be only applicable to the crowd of mild symptoms；Controversies in hormone replacement in the elderly is the primary treatments of Woman climacteric symptom, can be mitigated
The cardiovascular symptoms such as hectic fever, perspiration, mitigate the mental symptoms such as depression and anxiety, agitation, and other menopause symptoms can be alleviated, but
Estrogen long-term use may cause reproductive system proliferative lesion, increase the incidence of carcinoma of endometrium and breast cancer, and have
The adverse reactions such as water-sodium retention, increase cardiovascular and cerebrovascular danger；Phytoestrogen is that one kind is widely present in plant, structure and
Estrogen is similar and has the natural active matter of estrogen efficiency, has prevention and treatment women's climacteric syndrome activity.
In recent years, phytoestrogen turns into the conventional raw material of conditioning climacteric metancholia health food, including isoflavones, dyewood
The sources such as element, the root of kudzu vine.However, the excessive such material of intake there may be certain health risk, especially with reproductive system work(
There can be close association with genital system；Chinese medicine adverse reaction is small, can shorten the course for the treatment of, improve curative effect, reduce recurrence,
Make the life better quality, but lack unified objective syndrome differential diagnosis standard and curative effect determinate standard, lack effect Gao Fangjian medicine, lead
Its advantage in terms of clinical efficacy is caused to be difficult to promote.In addition, more than 90% climacteric crowd refuses medicine due to psychological application
The side effect of drug therapy is treated or feared, osteoporosis, hypertension, high fat of blood, hyperglycaemia etc. occurs after causing 60 years old
Symptom crowd is numerous.With health of people health care consciousness strengthen, for positive effect, it is safe, have no side effect it is pure natural
Advocating for integration of drinking and medicinal herbs group food turns into trend, so the pure natural dietary product tool of exploitation prevention and conditioning menopause symptom
There is very important meaning.
The content of the invention
Instant invention overcomes the defects of prior art, there is provided a kind of asparagus composition for preventing and nursing one's health menopause symptom
And its application, the raw material of said composition selected from food, new raw-food material and are both all food and the natural component of medicine, energy
Enough it is applied to the preparation of food, health food or medicine, pure natural no added, prescription is based on non-hormone interference method, compatibility
Science, it is significant effect, safe and have no side effect.
The present invention concrete technical scheme be：
A kind of asparagus composition for preventing and nursing one's health menopause symptom, key point are that described asparagus composition includes pressing
According to 240-300 parts Germinatus Phragmitis extract of mass ratio compatibility, 16-24 parts casein active peptide, 16-24 part purple sweetpotatos extract,
30-40 parts hippophae rhamnoides, 18-30 parts Rhizoma Polygonati extract, 10-20 parts perilla leaf extract, 6-10 parts γ-aminobutyric acid and
4-8 part theanine.
Described asparagus composition includes 260-280 parts Germinatus Phragmitis extract, the 18-22 part junket eggs according to mass ratio compatibility
White active peptide, 18-22 part purple sweetpotatos extract, 32-38 parts hippophae rhamnoides, 22-26 parts Rhizoma Polygonati extract, 12-18 part purple perillas
Leaf extract, 7-9 parts γ-aminobutyric acid and 5-7 part theanine.
Described asparagus composition includes 270 parts of Germinatus Phragmitis extracts, the 20 parts of active caseins according to mass ratio compatibility
Peptide, 20 parts of purple sweetpotato extracts, 35 parts of hippophae rhamnoides, 24 parts of Rhizoma Polygonati extracts, 15 parts of perilla leaf extracts, 8 parts of gamma-aminos
Butyric acid and 6 parts of theanine.
Asparagus saponin content >=12g/100g in described Germinatus Phragmitis extract.
Described casein active peptide is that molecular weight is less than after protease hydrolytic using bovine casein as raw material
5000Da peptides product.
Anthocyanin content >=20g/100g in described purple sweetpotato extract.
Content >=10g/100g of Hippophate flavone in described hippophae rhamnoides.
Siberian solomonseal rhizome polysaccharide content >=20g/100g in described Rhizoma Polygonati extract.
Described Germinatus Phragmitis extract, purple sweetpotato extract, hippophae rhamnoides, Rhizoma Polygonati extract and perilla leaf extract
Extraction solvent is water or ethanol.
Asparagus composition as described above is preparing medicine, food and the health food of prevention and conditioning menopause symptom
In application.
The beneficial effects of the invention are as follows：Germinatus Phragmitis extract, casein active peptide play regulation nerve in the present composition
The horizontal equilibriums such as mediator serotonin, dopamine, norepinephrine, make various neurotransmitters tend to the content necessarily stablized with
Ratio, so as to improve the symptom of the disorderly depression and anxiety triggered of climacteric neurotransmitter, agitation, suspicion, insomnia etc.；It is purple
Rhizoma Dioscoreae esculentae extract, hippophae rhamnoides play anti-oxidant, removing free radical, fundamentally play and delay body tissue aging to act on；
Germinatus Phragmitis extract, Rhizoma Polygonati extract, perilla leaf extract joint can play obvious effect for reducing blood fat, can prevent climacteric women
The generation of angiocardiopathy；γ-aminobutyric acid, theanine play calm nerve, hypotensive, help to alleviate climacteric palpitaition,
The symptom such as nervous, uncomfortable in chest, dizzy.
Prescription integrates each taste raw material different activities composition, stablized by anti-oxidant, removing free radical, regulation vegetative nerve,
Improve the pharmacological actions such as neurotransmitter secretion level, lowering blood pressure and blood fat, played assist according to different mechanism of action Mutiple Targets respectively
Same synergistic effect, in the case where not adding any exogenous hormones or estrogen-like composition, fundamentally nurse one's health global tissue machine
Can, delay climacteric to occur, develop and improve climacteric metancholia symptom.The raw material of composition is all selected from food, new food
Raw material and it is both food the natural component of medicine, no added chemical addition agent, prescription are done based on non-hormone or estrogen-like again
Pre- principle, compatibility science are significant effect, safe and have no side effect.
Embodiment
The present invention relates to a kind of asparagus composition for preventing and nursing one's health menopause symptom and its application, the combination of described asparagus
Thing includes the 240-300 parts Germinatus Phragmitis extract, 16-24 parts casein active peptide, 16-24 part purple sweetpotatos according to mass ratio compatibility
Extract, 30-40 parts hippophae rhamnoides, 18-30 parts Rhizoma Polygonati extract, 10-20 parts perilla leaf extract, 6-10 part gamma-aminos
Butyric acid and 4-8 part theanine, said composition can also be applied in the preparation of food, health food or medicine.
Asparagus is Liliaceae Asparagus perennial root herbaceous plant, alias asparagus, asparagus, is had very high
Nutritive value and medical value, ten big famous dish of the world is listed in, is high-grade vegetables of the pin to European ＆ American Market, China《Legendary god of farming's book on Chinese herbal medicine
Through》In, " on top grade " is classified as, is only second to ginseng；Asparagus slightly warm in nature, bitter but sweet flavor, modern study show, contain in asparagus
The various active composition such as polysaccharide, saponins, flavonoids, there is reducing blood lipid, improve immunity, anti-ageing health-care effect of waiting for a long time.
Casein active peptide is using bovine casein as raw material, and its molecular weight is less than 5000Da's after protease hydrolytic
Peptides product, there are bioactive short peptides that are different, having multiple functions in it, including with promoting calcium, iron absorption function
CPP (CPP), the antihypertensive peptide (ACE) with regulation blood pressure function, the promotion with raising immunologic function gulp down
Phagocyte effect peptide, have and adjust neurergic neuroleptic peptide etc., casein active peptide comes from lactoprotein, and the mankind for
The edible existing considerably long history of lactoprotein.The life science center (FASEB) of experimental biology federation of the U.S., state
The internal authority mechanism such as border food and medicine Surveillance Authority (FDA) and food security office of European Union (EFSA) thinks the water of protein
Solution product will not damage health；In Europe, obtained by the low irritability babies ' formula milk powder of casein hydrolysate production
To circulating extensively, the existing biologically active peptide for partly coming from dairy products is applied to health food, nutrition fortifier and doctor at present
Treat medicine etc..
Purple sweetpotato is also known as purple potato, and potato meat is in purple to darkviolet, and rich in anthocyanidin, anthocyanidin therein is mainly anthocyanin class
Pigment, it is flavonoid class compound, there is the various biological functions such as anti-oxidant, removing free radical, anti-aging, reducing blood lipid, extensively
It is general to be applied to the fields such as food processing, medicine, cosmetics.
Sea-buckthorn, also known as vinegar willow, black thorn, acid thorn, there is " natural complex treasure-house ", the laudatory title in " nutrition and health care source ", its
Containing abundant vitamin, amino acid, trace element, polyphenol, flavonoids isoreactivity material, there is anti-oxidant, protection heart and brain blood
The pharmacological activity such as pipe.
Sealwort is the dry rhizome of liliaceous plant P. kingianum, and ancient times sealwort just has the title of " alive for evermore, promote longevity ",
Modern study shows that Siberian solomonseal rhizome polysaccharide is active component main in sealwort, have anti-oxidant, anti-inflammatory, antibacterial, regulation blood pressure and blood lipoid,
The effect such as antiviral, strengthen immunity and improvement memory.
Purple perilla, the red Soviet Union of alias, fragrant Soviet Union, red Soviet Union, are traditional medical and edible dual purpose plants.Perilla leaf containing multiple nutritional components and
The various bioactivators such as Rosmarinic acid, polyphenol, flavones, perillaldehyde, polysaccharide, there is anti-oxidant, reducing blood lipid and other effects.
γ-aminobutyric acid is a kind of natural amino acid of non-protein composition, is that mammalian central nervous system is a kind of main
The inhibitory neurotransmitter wanted, numerous studies show that food-borne γ-aminobutyric acid has hypotensive, promotes sleep, enhancing memory
The physiological actions such as power, antianxiety, new raw-food material was approved in 2009.
Theanine is a kind of mainly amino acid unique present in Theaceae plant, systematic naming method be N-ethyl-L-
Glutamine, there is good health-care effect in neuroprotection, calmness, regulation mood, raising cognitive ability etc., in 2014
It is approved for new raw-food material.
Women during climacteric has following physiological change：1) endocrine change：Climacteric women ovary starts
Failing, the stimulation of granular cell and thecacells to promoting sexual gland hormone is insensitive in ovarian follicle, and synthesis and secretion estrogen are reduced,
Cause the imbalance of Hypothalamus-pituitary-rush gonad axis activity, endocrine balance is broken；2) change of oxidation resistance：In machine
During the continuous aging of body, eliminating the activity of the peroxidase of free radical in vivo constantly reduces, and causes the generation of free radical
It is destroyed with poised state is eliminated, the free radical constantly accumulated will produce a series of attack to cell tissue.Climacteric female
Property plasma lipid peroxide significantly raised compared with the adolescence, and the activity of superoxide dismutase and glutathione peroxidase compared with
Adolescence significantly reduces；3) cardiovascular change：After women enters into the climacteric period, triglycerides (TG), T-CHOL in blood
(TC) and low-density lipoprotein (LDL) has raised, and fibrinogen, uric acid and insulin tolerance rise, if more
Term, crowd was not nursed one's health, will be easily caused the rise of its blood fat, blood pressure rise, blood glucose rise, and be caused atherosclerotic plaque
Easily formed, the probability for suffering from cardiovascular and cerebrovascular disease greatly increases；4) change of neurotransmitter：According to Menopause epidemiology
Investigation finds that the factors such as menopause symptom and age, occupation, marital status, home background, income are relevant.
Think by molecular biological analysis, because these social family factorses produce the different degrees of heart to climacteric age bracket women
Pressure is managed, severe patient triggers violent anxious state of mind, and acutely anxious state of mind can cause serum 5-HT (5-HT) horizontal obvious
Reduce, and then cause estrogen level big ups and downs.Due to 5-HT acceptors and gonadotropin-releasing hormone (GRH) reciprocal causation relation,
Horizontal decline of 5-HT can cause decrease in estrogen, and decrease in estrogen also results in the horizontal declines of 5-HT.So female swash
Plain big ups and downs and then cause neurotransmitter (including 5-HT) disorderly, thermoregulatory center is disorderly or mood regulation so as to occur
Maincenter disorder, or both occurs simultaneously.Hectic fever, night sweat, the disorder meeting of mood regulation maincenter can occur for thermoregulatory center disorder
The symptoms such as generation insomnia, anxiety, depression.It is main most straight during the symptoms such as hectic fever, night sweat, insomnia, anxiety, depression occur
The reason for connecing is that neurotransmitter (mainly 5-HT) is disorderly.
Germinatus Phragmitis extract of the present invention, casein active peptide, which are combined, to play a role, and can adjust neurotransmitter serotonin, more
The horizontal equilibriums such as bar amine, norepinephrine, dopamine, make various neurotransmitters tend to the content and ratio necessarily stablized, from
And directly improve the disorderly hectic fever triggered of climacteric neurotransmitter, night sweat, depression and anxiety, agitation, suspicion, insomnia etc.
Symptom, estrogen level secretion is adjusted indirectly, improves its big ups and downs phenomenon；Purple sweetpotato extract, hippophae rhamnoides play anti-
Oxidation, free radical is removed, fundamentally play a part of delaying body tissue aging, auxiliary delays climacteric to develop indirectly, changes
Kind menopause symptom；Germinatus Phragmitis extract, Rhizoma Polygonati extract, perilla leaf extract synergy can play obvious reducing blood lipid and make
With the generation of climacteric women angiocardiopathy can be prevented；γ-aminobutyric acid, theanine play calm nerve, hypotensive is made
With helping to alleviate climacteric palpitaition, the symptom such as nervous, uncomfortable in chest.Component integrates each taste raw material different activities composition, passes through antioxygen
To change, remove free radical, regulation vegetative nerve stabilization, improvement neurotransmitter secretion is horizontal, the pharmacological action such as lowering blood pressure and blood fat,
Respectively according to different mechanism of action Mutiple Targets play synergistic function, do not add any exogenous hormones or estrogen-like into
In the case of point, global tissue function is fundamentally nursed one's health, delays climacteric to occur, develop and improves climacteric metancholia symptom.
Composition in the present invention can prevent involutional generation, nurse one's health, mitigate the various symptoms of climacteric metancholia,
Including Tidal fever with perspiration, insomnia, irritable, depressed suspicion, dizziness, tired and other menopause symptoms, the specific effect of composition
Fruit is illustrated by specific embodiment.
Embodiment 1, first, between selecting 40~60 years old, within menopause 5 years and have a climacteric metancholia symptom encloses menopause
The people of phase women 120 is research object, excludes more than 5 years persons of menopause or more than 60 years old person, gestation or women breast-feeding their children, allergic constitution
Person, late deformity, maimed person, disability person, it is associated with the severe primaries such as angiocarpy, the cerebrovascular, liver, kidney and hemopoietic system
Disease, mental patient, take within 3 months before experiment other related drugs, health food person, do not meet inclusive criteria, not by
Regulation is edible, can not judge the infull impact effect of curative effect and data and safe sex determination person；
Selected 120 people randomized double-blind is divided into two groups, every group of 60 people, two groups are respectively test group and control group, two groups
Age, body weight, the inferior upper no significant difference of index distribution of motherhood, the asparagus composition that test group is used in the oral present invention,
Asparagus composition includes carrying according to the 270 parts of Germinatus Phragmitis extracts, 20 parts of casein active peptides, 20 parts of purple sweetpotatos of mass ratio compatibility
Take thing, 35 parts of hippophae rhamnoides, 24 parts of Rhizoma Polygonati extracts, 15 parts of perilla leaf extracts, 8 parts of γ-aminobutyric acids and 6 parts of tea ammonia
Acid, Germinatus Phragmitis extract, purple sweetpotato extract, hippophae rhamnoides, the Extraction solvent of Rhizoma Polygonati extract and perilla leaf extract are
Water or ethanol, wherein, asparagus saponin content is 15g/100g in Germinatus Phragmitis extract, and casein active peptide is with bovine casein
For raw material, molecular weight is less than 5000Da peptides product after protease hydrolytic, and anthocyanin content is in purple sweetpotato extract
30g/100g, the content of Hippophate flavone is 15g/100g in hippophae rhamnoides, and Siberian solomonseal rhizome polysaccharide content is 25g/ in Rhizoma Polygonati extract
100g, it can be liquid or solid that the asparagus composition, which prepares the formulation to be formed, including beverage (solid beverage), convenient food
Product, dairy products, biscuit, tablet, capsule, oral liquid, pill or powder, the present embodiment test group are carried using asparagus of the present invention
Thing is taken according to product made from solid beverage processing technology, 20g/ bags, and control group then uses identical bag made of oral starch
The preparation of dress, oral daily once 2 bags every time, two groups of oral doses are identical, and duration of trial is 6 months, and record in detail is oral daily
The situation that symptomatology improves afterwards, experimental period terminate after check the accuracy of semiograhy and whether there is and miss medicine or malaise symptoms,
Then the detecting appraisal of the effect of final is carried out, Testing index includes Kupperman scorings, and (Kupperman is commented with hormonal readiness
Point：Women's climacteric syndrome is evaluated using international uniform evaluation criterion Kupperman scoring questionnaires；Hormone water
It is flat：All patients with opening hormone by doctor after taking before product is taken in checking request slip, in the second sky of menstrual onset
Abdomen blood drawing measurement follicle-stimulating hormone (FSH) (FSH), estradiol (E2)), Kupperman appraisal results are shown in Table 1, the detection knot of hormonal readiness
Fruit is shown in Table 2；
The change situation (x scholar s) of Kupperman scorings indices after table 1 is taken 6 months
(note：The * P compared with before treatment<O.05)
Kupperman point systems are edited according to Cao Zeyi《Chinese gynecotokology》(volume two) menopause transition and post menopausal
Methods of marking in disease.Test group took product of the present invention after 6 months, from itself relatively from the point of view of, test group objects all 12
Item index is improved, and scoring reduces statistically significant；And control group is except Tidal fever with perspiration, palpitaition, urinary infection, property
Although other outer indexs of weather are notable not as test group regulation, also make moderate progress, this is probably because placebo produces
The reason of raw subjective effect, it can be detected in conjunction with the data of table 2.
Table 2 takes the product influence (x scholar s) to FSH, E2 in climacteric metancholia women blood in 6 months
FSH is controlled by hypothalamus gonadotropin releasing hormone by pituitary secretion, while by the anti-of ovary female hormone E2
Feedback regulation and control, by determining FSH, it will be appreciated that pituitary endocrine function, the functional status of hypothalamus and ovary can be also understood indirectly,
FSH levels increase, and prompt women ovarian function to reduce, and FSH reduces explanation product to delaying climacteric metancholia to have effect；E2
Mainly generated by placenta when ovary follicle, corpus luteum and gestation, the horizontal rise explanation products of E2 are to delaying climacteric metancholia to have work
With.
Considered by Kupperman scorings and hormonal readiness testing result, oral asparagus composition energy of the present invention
The symptom of the climacteric metancholia of test group crowd is enough obviously improved, has remarkable result for preventing and nursing one's health menopause symptom.
Asparagus composition in the present invention can also be applied to prevent and the food of conditioning climacteric metancholia, medicine or
In the preparation of health food.
Embodiment 2, the another embodiment of the asparagus composition oral as test group in embodiment 1, asparagus combination
Thing includes the 250 parts of Germinatus Phragmitis extracts, 23 parts of casein active peptides, 17 parts of purple sweetpotato extracts, 39 according to mass ratio compatibility
Part hippophae rhamnoides, 20 parts of Rhizoma Polygonati extracts, 13 parts of perilla leaf extracts, 9 parts of γ-aminobutyric acids and 5 parts of theanine, according to
Beverage product, every bottle of 50ml is made in asparagus composition by beverage processing technology.
Embodiment 3, the another embodiment of the asparagus composition oral as test group in embodiment 1, asparagus combination
Thing includes the 290 parts of Germinatus Phragmitis extracts, 17 parts of casein active peptides, 23 parts of purple sweetpotato extracts, 33 according to mass ratio compatibility
Part hippophae rhamnoides, 27 parts of Rhizoma Polygonati extracts, 17 parts of perilla leaf extracts, 7 parts of γ-aminobutyric acids and 7 parts of theanine, according to
Tablet product, every 1g is made in asparagus composition by tablet machining process.
Take the asparagus composition in the present invention and either take the food containing asparagus composition, medicine or health care food
Product, the symptom of climacteric metancholia can be significantly nursed one's health, be below three examples：
Example 1, Mr. Wang, female, 49 years old, because son graduates from university, to local work farther out, performance silence, hypologia, frequent sound of sighing
Sound is sighed, and easy sentiment is shed tears.Night egersis, refuse diet, have a worried look all day, it is believed that life is meaningless, in the world all
All it is empty, there is delusion of hypocenesthesia.Climacteric metancholia is diagnosed as, takes the product of the embodiment of the present invention 1, it is daily oral 1 time, every time
2 bags, self-induction take a favorable turn within 10 days, and mood is light, sleep improvement, and state of mind remarkable improvement, gradually there is confidence after one month, after
Continuous to take 2 months, symptom is wholly absent, and it refills hope to life；
Example 2, Zhang, female, 54 years old, because of flushed face, dysphoria, have palpitation weak, a burst of warm etc. repeatedly goes to hospital just
Examine, it is invalid successively to take multi-medicament treatment with " diabetes, cardiac neurosis " etc., and existing mood becomes depressed and had
World-weary mood, sleep is poor, vexed, and the whole body is uncomfortable.The product of the embodiment of the present invention 2 is taken, 3 times a day, is slept after 1 bottle every time, 7 days
Quality has been taken a turn for the better, and mood has been releived.After taking 2 months, all diseases have improvement.After half a year, its Tidal fever with perspiration symptom disappears,
State of mind juvenescence；
Example 3, Ma, female, 51 years old, private prosecution paroxysmal hectic fever, perspiration, palpitaition, insomnia were more than July, with irritable, note
The medication effect such as recall power to fall sharply, have a pain in the back, occasionally there is headache, discomfort uncomfortable in chest etc., take oryzanol, acanthopanax root tablet certainly and stabilize is bad,
Nearly first quarter moon carrys out above-mentioned symptom and gradually aggravates the patients because being suspected to have grave illness and row whole body physical examination, has excluded high blood pressure, coronary heart disease and first
Shape gland disease etc., the product of the embodiment of the present invention 3 is taken, 2 times a day, 1 tablet once, and after one month, its symptom has been alleviated, three
Menopause symptom disappears after month.
Claims (10)
- A kind of 1. asparagus composition for preventing and nursing one's health menopause symptom, it is characterised in that：Described asparagus composition includes pressing According to 240-300 parts Germinatus Phragmitis extract of mass ratio compatibility, 16-24 parts casein active peptide, 16-24 part purple sweetpotatos extract, 30-40 parts hippophae rhamnoides, 18-30 parts Rhizoma Polygonati extract, 10-20 parts perilla leaf extract, 6-10 parts γ-aminobutyric acid and 4-8 part theanine.
- A kind of 2. asparagus composition for preventing and nursing one's health menopause symptom according to claim 1, it is characterised in that：It is described Asparagus composition include according to mass ratio compatibility 260-280 parts Germinatus Phragmitis extract, 18-22 parts casein active peptide, 18- 22 parts of purple sweetpotato extracts, 32-38 parts hippophae rhamnoides, 22-26 parts Rhizoma Polygonati extract, 12-18 parts perilla leaf extract, 7-9 Part γ-aminobutyric acid and 5-7 part theanine.
- A kind of 3. asparagus composition for preventing and nursing one's health menopause symptom according to claim 1, it is characterised in that：It is described Asparagus composition include according to mass ratio compatibility 270 parts of Germinatus Phragmitis extracts, 20 parts of casein active peptides, 20 parts of purple sweetpotatos Extract, 35 parts of hippophae rhamnoides, 24 parts of Rhizoma Polygonati extracts, 15 parts of perilla leaf extracts, 8 parts of γ-aminobutyric acids and 6 parts of tea Propylhomoserin.
- A kind of 4. asparagus composition for preventing and nursing one's health menopause symptom according to claim 1, it is characterised in that：It is described Germinatus Phragmitis extract in asparagus saponin content >=12g/100g.
- A kind of 5. asparagus composition for preventing and nursing one's health menopause symptom according to claim 1, it is characterised in that：It is described Casein active peptide be using bovine casein as raw material, after protease hydrolytic molecular weight less than 5000Da peptides produce Product.
- A kind of 6. asparagus composition for preventing and nursing one's health menopause symptom according to claim 1, it is characterised in that：It is described Purple sweetpotato extract in anthocyanin content >=20g/100g.
- A kind of 7. asparagus composition for preventing and nursing one's health menopause symptom according to claim 1, it is characterised in that：It is described Hippophae rhamnoides in Hippophate flavone content >=10g/100g.
- A kind of 8. asparagus composition for preventing and nursing one's health menopause symptom according to claim 1, it is characterised in that：It is described Rhizoma Polygonati extract in Siberian solomonseal rhizome polysaccharide content >=20g/100g.
- A kind of 9. asparagus composition for preventing and nursing one's health menopause symptom according to claim 1, it is characterised in that：It is described Germinatus Phragmitis extract, purple sweetpotato extract, hippophae rhamnoides, the Extraction solvent of Rhizoma Polygonati extract and perilla leaf extract be water Or ethanol.
- 10. any one asparagus composition as described in claim 1-9 prepare the medicine of prevention and conditioning menopause symptom, Application in food and health food.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108714208A (en) * | 2018-06-21 | 2018-10-30 | 北京斯利安药业有限公司 | Composition, preparation method, using and relieve stress, improve sleep product |
| CN109170455A (en) * | 2018-08-22 | 2019-01-11 | 天津科技大学 | It is a kind of rich in Mulberry anthocyanin and the solid beverage and preparation method thereof that can be relieved perimenopausal syndrome |
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| CN106666746A (en) * | 2017-02-04 | 2017-05-17 | 秦皇岛长胜营养健康科技有限公司 | Asparagus composition with neurotransmitter balance adjusting function and preparation method thereof as well as asparagus composition powder |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106666746A (en) * | 2017-02-04 | 2017-05-17 | 秦皇岛长胜营养健康科技有限公司 | Asparagus composition with neurotransmitter balance adjusting function and preparation method thereof as well as asparagus composition powder |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108714208A (en) * | 2018-06-21 | 2018-10-30 | 北京斯利安药业有限公司 | Composition, preparation method, using and relieve stress, improve sleep product |
| CN109170455A (en) * | 2018-08-22 | 2019-01-11 | 天津科技大学 | It is a kind of rich in Mulberry anthocyanin and the solid beverage and preparation method thereof that can be relieved perimenopausal syndrome |
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Application publication date: 20180316 |