CN107456401A - 一种壳聚糖洗手液 - Google Patents
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
- A61K8/355—Quinones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- Animal Behavior & Ethology (AREA)
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Abstract
本发明公开一种壳聚糖洗手液，按重量百分比计，各原料及其用量分别为：壳聚糖0.5～3％、月桂醇醚磷酸酯钾1～5％、十二烷基葡萄糖苷5～9％、甘油1～3％、柠檬酸0.1～0.8％、氯化钠1～4％、芦荟大黄素0.01～0.3％、余量为去离子水。本发明一种壳聚糖洗手液能够清洁手部肌肤，并有效抑菌，且对皮肤无刺激性，使用更加安全健康。
Description
技术领域
本发明涉及护肤用品技术领域，具体涉及的是一种壳聚糖洗手液。
背景技术
由于洗手液在使用后可以有效避免细菌交叉污染，成为了公共场所洗涤用品的首选。如申请号为200910187739.7的中国发明专利公开了一种杀菌洗手液，它是由以下组分按下述重量份数比组成的：硬脂酸∶硬脂酸乙二醇酯∶拉丝粉∶水∶玫瑰花提取液∶樟树叶提取液＝5-20∶1-10∶0.5-4∶20-50∶10-25∶15-35。该发明中的杀菌洗手液添加了玫瑰花提取液，还采用樟树叶提取液释放的挥发性有机物来杀菌，但杀菌抑菌效果仍不理想。
发明内容
本发明的目的在于提供一种壳聚糖洗手液，该壳聚糖洗手液具有广谱抗菌性，杀菌效果好，且对皮肤无刺激作用。
为了达成上述目的，本发明的解决方案是：
一种壳聚糖洗手液，按重量百分比计，包括如下用量的原料：
一种壳聚糖洗手液，按重量百分比计，包括如下用量的原料：
该壳聚糖洗手液的制备可以采用实验室方法制备，具体步骤如下：以配制100g产品为基准，用200ml的烧杯，先按照配方要求分别加入月桂醇醚磷酸酯钾1～5g、十二烷基葡萄糖苷5～9g、甘油1～3g和50mL的去离子水，加热至60-70℃，待搅拌均匀后降温至30-40℃，然后加入壳聚糖0.5～3g、柠檬酸0.1～0.8g、芦荟大黄素0.01～0.3g和余量的去离子水，搅拌均匀，最后在搅拌下缓慢加入氯化钠1～4g调节产品的粘度，即可得到本发明壳聚糖洗手液。
该壳聚糖洗手液的制备还可以采用本行业通用的方法制备，具体步骤如下：在混合反应釜中，先加入配方比例的去离子水，加热至60-70℃，在搅拌条件下，然后加入配方比例的月桂醇醚磷酸酯钾、十二烷基葡萄糖苷和甘油，搅拌均匀后降温至30-40℃，最后加入壳聚糖、柠檬酸、芦荟大黄素和氯化钠，搅拌均匀，即可得到本发明壳聚糖洗手液。
在本发明中根据客户需要，还可以添加其他原料，如防腐剂(卡松、防腐剂ECOCIDEITH2)、香精以及颜料等，其他原料的加入可基本实现其各自的功能，通常不会影响本发明的基本性能，因此本领域技术人员无需付出创造性劳动即可实施。
采用上述技术方案后，本发明一种壳聚糖洗手液，相对于现有技术，本发明的创新之处在于配方的选择，在原料中加入天然提取物壳聚糖，由于壳聚糖的多聚阳离子，一是易与真菌细胞表面带负电荷的基团作用，从而改变病原菌细胞膜的流动性和通透性；二是干扰DNA的复制与转录；三是阻断病原菌代谢，由此得到的本发明一种壳聚糖洗手液能够清洁手部肌肤，并有效抑菌，且对皮肤无刺激作用，使用更加安全健康。
具体实施方式
为了进一步解释本发明的技术方案，下面通过具体实施例来对本发明进行详细阐述。
一、一种壳聚糖洗手液的制备
实施例1-3
1、原料准备
按照表1所指定的对应实施例1-3的原料及其用量，进行原料称取，％指重量百分比，原料以有效物含100wt％计。
2、制备方法
在混合反应釜中，先加入配方比例的去离子水，加热至60-70℃，在搅拌条件下，然后加入配方比例的月桂醇醚磷酸酯钾、十二烷基葡萄糖苷和甘油，搅拌均匀后降温至30-40℃，最后加入壳聚糖、柠檬酸、芦荟大黄素和氯化钠，搅拌均匀，即可得到本发明壳聚糖洗手液。
表1 该壳聚糖洗手液的原料及其用量单位：％
二、抑菌活性测定：
按照行业标准QB/T2850-2007抗菌抑菌型洗涤剂，进行抑菌效果测试，作用浓度均为1wt％，作用时间均为20分钟，具体检测数据详见表2。
表2 该壳聚糖洗手液的抑菌效果测试结果
通过与未加入壳聚糖的对比例1进行实验对照发现，添加壳聚糖的本发明壳聚糖洗手液抗菌抑菌效果更加明显，通过与未加入芦荟大黄素的对比例2进行试验对照发现，添加芦荟大黄素的本发明壳聚糖洗手液抑菌抗菌效果更加明显，说明壳聚糖和芦荟大黄素都具有一定的抗菌性，并且两者具有协同作用，可以提高洗手液的抗菌性能。
上述实施例并非限定本发明的产品形态和式样，任何所属技术领域的普通技术人员对其所做的适当变化或修饰，皆应视为不脱离本发明的专利范畴。
Claims (2)
1.一种壳聚糖洗手液，其特征在于：按重量百分比计，包括如下用量的原料：
2.根据权利要求1所述的一种壳聚糖洗手液，其特征在于：按重量百分比计，包括如下用量的原料：
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109528549A (zh) * | 2018-12-21 | 2019-03-29 | 上海理工大学 | 一种壳聚糖抗菌润肤免水洗洗手液及其制备方法 |
| CN109706744A (zh) * | 2018-12-03 | 2019-05-03 | 广州润虹医药科技股份有限公司 | 一种快速止血、抗菌水胶体油纱及其制备方法 |
| CN110664667A (zh) * | 2019-11-19 | 2020-01-10 | 广州倍健医疗用品有限公司 | 一种快速灭菌的组合物及其应用 |
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| CN103565702A (zh) * | 2013-11-12 | 2014-02-12 | 上海方木精细化工有限公司 | 茶树精油洗手液 |
| CN105342934A (zh) * | 2015-12-11 | 2016-02-24 | 饶雅琴 | 一种茶树油免洗洗手液及其制备方法 |
| CN105708764A (zh) * | 2016-03-24 | 2016-06-29 | 攀柔莎（江苏）生物科技股份有限公司 | 一种含芦荟提取物的洗手液 |
| CN106726960A (zh) * | 2016-12-24 | 2017-05-31 | 江西宜信堂医疗科技有限公司 | 一种薰衣草洗手液及其制备方法 |
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- 2017-08-14 CN CN201710692924.6A patent/CN107456401A/zh active Pending
Patent Citations (5)
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| CN103565702A (zh) * | 2013-11-12 | 2014-02-12 | 上海方木精细化工有限公司 | 茶树精油洗手液 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109706744A (zh) * | 2018-12-03 | 2019-05-03 | 广州润虹医药科技股份有限公司 | 一种快速止血、抗菌水胶体油纱及其制备方法 |
| CN109528549A (zh) * | 2018-12-21 | 2019-03-29 | 上海理工大学 | 一种壳聚糖抗菌润肤免水洗洗手液及其制备方法 |
| CN110664667A (zh) * | 2019-11-19 | 2020-01-10 | 广州倍健医疗用品有限公司 | 一种快速灭菌的组合物及其应用 |
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Application publication date: 20171212 |