CN107201277A - A kind of contact lens care solution - Google Patents
A kind of contact lens care solution Download PDFInfo
- Publication number
- CN107201277A CN107201277A CN201710475736.8A CN201710475736A CN107201277A CN 107201277 A CN107201277 A CN 107201277A CN 201710475736 A CN201710475736 A CN 201710475736A CN 107201277 A CN107201277 A CN 107201277A
- Authority
- CN
- China
- Prior art keywords
- contact lens
- lens care
- care solution
- solution according
- franchise
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229920002413 Polyhexanide Polymers 0.000 claims abstract description 15
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims abstract description 13
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims abstract description 13
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims abstract description 13
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims abstract description 13
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 claims abstract description 12
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229960000502 poloxamer Drugs 0.000 claims abstract description 12
- 229920001983 poloxamer Polymers 0.000 claims abstract description 12
- 230000001954 sterilising effect Effects 0.000 claims description 13
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 10
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 238000001914 filtration Methods 0.000 claims description 4
- 239000011780 sodium chloride Substances 0.000 claims description 4
- 239000004695 Polyether sulfone Substances 0.000 claims description 3
- 229910021538 borax Inorganic materials 0.000 claims description 3
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims description 3
- 239000004327 boric acid Substances 0.000 claims description 3
- 230000009089 cytolysis Effects 0.000 claims description 3
- 239000004033 plastic Substances 0.000 claims description 3
- 229920006393 polyether sulfone Polymers 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- 239000004328 sodium tetraborate Substances 0.000 claims description 3
- 235000010339 sodium tetraborate Nutrition 0.000 claims description 3
- 241000894006 Bacteria Species 0.000 abstract description 10
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 7
- 238000000034 method Methods 0.000 abstract description 3
- FRXSZNDVFUDTIR-UHFFFAOYSA-N 6-methoxy-1,2,3,4-tetrahydroquinoline Chemical compound N1CCCC2=CC(OC)=CC=C21 FRXSZNDVFUDTIR-UHFFFAOYSA-N 0.000 abstract description 2
- 241000700605 Viruses Species 0.000 abstract description 2
- 238000010521 absorption reaction Methods 0.000 abstract description 2
- 230000006907 apoptotic process Effects 0.000 abstract description 2
- 230000015572 biosynthetic process Effects 0.000 abstract description 2
- 210000000170 cell membrane Anatomy 0.000 abstract description 2
- 150000002596 lactones Chemical class 0.000 abstract description 2
- 210000002706 plastid Anatomy 0.000 abstract description 2
- 230000001681 protective effect Effects 0.000 abstract description 2
- 238000003786 synthesis reaction Methods 0.000 abstract description 2
- -1 Propane diols Chemical class 0.000 abstract 1
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N dimethylmethane Natural products CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000001294 propane Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 4
- 238000004659 sterilization and disinfection Methods 0.000 description 4
- 230000003750 conditioning effect Effects 0.000 description 3
- 230000003204 osmotic effect Effects 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 230000002335 preservative effect Effects 0.000 description 3
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 208000037656 Respiratory Sounds Diseases 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 241000208292 Solanaceae Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 229960001484 edetic acid Drugs 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/722—Ethers of polyoxyalkylene glycols having mixed oxyalkylene groups; Polyalkoxylated fatty alcohols or polyalkoxylated alkylaryl alcohols with mixed oxyalkylele groups
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2003—Alcohols; Phenols
- C11D3/2041—Dihydric alcohols
- C11D3/2044—Dihydric alcohols linear
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/22—Carbohydrates or derivatives thereof
- C11D3/222—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin
- C11D3/225—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin etherified, e.g. CMC
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/26—Organic compounds containing nitrogen
- C11D3/33—Amino carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/37—Polymers
- C11D3/3703—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Eyeglasses (AREA)
Abstract
The invention discloses a kind of contact lens care solution, it is characterised in that：On the basis of the gross mass of the contact lens care solution, the contact lens care solution is made up of following each component：Hydroxypropyl methylcellulose 1.3mg/ml；Poloxamer 2mg/ml；Natrium adetate 1mg/ml；Poly hexamethylene biguanide 0.0018mg/ml；Propane diols 2mg/ml.The invention provides a kind of contact lens care solution; generally it is in electronegative all kinds of bacteriums, virus by using poly hexamethylene biguanide absorption; into cell membrane, suppress the synthesis of film lactones plastid, cause thalline apoptosis; reach optimal bactericidal effect; bactericidal effect is good, good protective effect is served to user, it is to avoid the potential safety hazard that the bacterium on contact lenses is caused to human body; technique is simple, it is easy to implement.
Description
Technical field
The present invention relates to conditioning liquid technical field, more particularly to a kind of contact lens care solution.
Background technology
Contact lens care solution is that contact lenses race will use daily, and the deposit of lens surface and pathogen must be first
Removed with conditioning liquid, so ensuing sterilization preservation could be carried out effectively.Because cleaning incomplete lens surface can remain
Deposit, when directly being sterilized, sterilization composition can only be combined with deposit, and can not be combined with pathogen, consequently, it is possible to kill
Bacterium composition cannot play bactericidal action.
The main component of contact lens care solution is sodium chloride and preservative etc., be mainly used in cleaning to biomaterial,
Sterilize, remove removing protein etc., it is undoubtedly essential for the people of contact lens wear.But some consumers' reflection is matched somebody with somebody
Occurs eye after wearing contact lens rubescent, the adverse reaction such as do not feel like oneself.Its main cause is user in contact lens care
Have what some mistaken ideas were caused in the use of liquid.The bactericidal effect of current contact lens care solution is not ideal enough, it is impossible to reach pre-
The effect of phase, so as to cause to cause human body certain infringement with certain potential safety hazard.
The content of the invention
The technical problem existed based on background technology, the present invention proposes a kind of contact lens care solution, with good
Bactericidal effect, improves the security of contact lens care solution, solves current contact lens care solution bactericidal effect and not enough manages
Think, it is impossible to the problem of producing a desired effect.
The present invention provides following technical scheme：A kind of contact lens care solution, it is characterised in that：Protected with the contact lenses
On the basis of the gross mass for managing liquid, the contact lens care solution is made up of following each component：
Hydroxypropyl methylcellulose 1.3mg/ml；
Poloxamer 2mg/ml；
Natrium adetate 1mg/ml；
Poly hexamethylene biguanide 0.0018mg/ml；
Propane diols 2mg/ml.
It is preferred that, the labelled amount of the hydroxypropyl methylcellulose is 1.3mg/ml, the franchise of the hydroxypropyl methylcellulose for ±
20%。
It is preferred that, the labelled amount 2mg/ml of the poloxamer, the franchise of the poloxamer is ± 20%.
It is preferred that, the labelled amount of the natrium adetate is 1mg/ml, and the franchise of the natrium adetate is ± 20%.
It is preferred that, the labelled amount of the poly hexamethylene biguanide is 0.0018mg/ml, and the poly hexamethylene biguanide is permitted
Difference is ± 20%.
It is preferred that, the labelled amount 2mg/ml of the propane diols, the franchise of the propane diols is ± 20%.
It is preferred that, the pH value of the contact lens care solution is 6.5-7.8.
It is preferred that, the osmotic pressure of the contact lens care solution is 260-340mOsm/kgH2O。
It is preferred that, the viscosity of the contact lens care solution is 1-5mPas.
It is preferred that, the preparation method of the contact lens care solution is following steps：
A, by hydroxypropyl methylcellulose in 80 ° of hot water disperse, add cold water hot-cold lysis；
B, will natrium adetate, boric acid, borax, sodium chloride, poloxamer and propane diols add pure water in dissolve；
C, two kinds of solution in step A and step B are well mixed；
D, poly hexamethylene biguanide added in the solution in step C, stirred；
E, the solution for obtaining step D are filtered through 0.45 μm and 0.22 μm of polyether sulfone sterilizing filter successively, the feed liquid after filtering
It is directly placed into sterilized plastic bottle, jumps a queue, covers sealing.
Generally it is in elecrtonegativity by using poly hexamethylene biguanide absorption the invention provides a kind of contact lens care solution
All kinds of bacteriums, virus, into cell membrane, suppress the synthesis of film lactones plastid, cause thalline apoptosis, reach optimal sterilization effect
Really, bactericidal effect is good, good protective effect is served to user, it is to avoid the bacterium on contact lenses is caused to human body
Potential safety hazard, technique is simple, it is easy to implement.
Embodiment
The technical scheme in the embodiment of the present invention is clearly and completely described below, it is clear that described embodiment
Only a part of embodiment of the invention, rather than whole embodiments.Based on the embodiment in the present invention, the common skill in this area
The every other embodiment that art personnel are obtained under the premise of creative work is not made, belongs to the model that the present invention is protected
Enclose.
The present invention provides a kind of technical scheme：A kind of contact lens care solution, using the gross mass of contact lens care solution as
Benchmark, contact lens care solution is made up of following each component：
Hydroxypropyl methylcellulose 1.3mg/ml；
Poloxamer 2mg/ml；
Natrium adetate 1mg/ml；
Poly hexamethylene biguanide 0.0018mg/ml；
Propane diols 2mg/ml.
In the present invention, the labelled amount of hydroxypropyl methylcellulose is 1.3mg/ml, and the franchise of hydroxypropyl methylcellulose is ± 20%, pool
Luo Shamu labelled amount 2mg/ml, the franchise of poloxamer is ± 20%, and the labelled amount of natrium adetate is 1mg/ml, edetic acid(EDTA)
The franchise of disodium is ± 20%, and the labelled amount of poly hexamethylene biguanide is 0.0018mg/ml, and the franchise of poly hexamethylene biguanide is
± 20%, the labelled amount 2mg/ml of propane diols, the franchise of propane diols is ± 20%, and the pH value of contact lens care solution is 6.5-7.8,
The osmotic pressure of contact lens care solution is 260-340mOsm/kgH2O, the viscosity of contact lens care solution is 1-5mPas.
The preparation method of contact lens care solution is following steps：
A, by hydroxypropyl methylcellulose in 80 ° of hot water disperse, add cold water hot-cold lysis；
B, will natrium adetate, boric acid, borax, sodium chloride, poloxamer and propane diols add pure water in dissolve；
C, two kinds of solution in step A and step B are well mixed；
D, poly hexamethylene biguanide added in the solution in step C, stirred；
E, the solution for obtaining step D are filtered through 0.45 μm and 0.22 μm of polyether sulfone sterilizing filter successively, the feed liquid after filtering
It is directly placed into sterilized plastic bottle, jumps a queue, covers sealing.
In the present invention, production environment is 10,000 grades of clear production areas, and all utensils contacted with feed liquid after filtering are both needed to
Sterilizing, keeps sterile and sterile working state.
Contact lens are operated using this product, its physical appearance is observed and should be：Contact lense is in conditioning liquid
7 times~10 times of amplification is visually observed, and should not have an impact the impurity normally used and beauty defects, such as spot, residual debris or crystalline substance
Branch bubble, and such as surface any defect of crackle, edge damage；Edge contour should be consistent with the shape facility that manufacturer designs,
Circumferential shape is uniform.
Sterilizing rate experiment is carried out to contact lens using this product, after acting on 6 hours, the Disinfection Effect of this product
Should：Sterilizing rate >=99.90% of Escherichia coli；Sterilizing rate >=99.90% of staphylococcus aureus；The sterilizing rate of Pseudomonas aeruginosa
>=99.90%；Sterilizing rate >=90.00% of Candida albicans（And bacterium number does not increase in 4 times of soak times）；Solanaceae reaping hook is mould
Sterilizing rate >=90.00% of bacterium（And bacterium number does not increase in 4 times of soak times）.
Preservative challenge test, wherein germ experiment are carried out to contact lens using this product：At 14 days, every kind of test organisms
Per milliliter restoration ecosystem bacterium number, average reduced value is no less than 3.0logs；After 14 days inoculate, at 28 days, every kind of test organisms
Concentration should reduce again, average reduced value at least 3.0logs；
Yeast and mold is tested：At 14 days, it is initial that every kind of test organisms should be maintained at or below its per milliliter restoration ecosystem bacterium number
Concentration, at 28 days, the concentration of every kind of test organisms should be maintained at or below the concentration for inoculating rear each test organisms（Experimental error ±
In 0.5logs）.
In the present invention, keeping life is 2 years, the outward appearance of product in 2 years terms of validity, loading amount, pH value, osmotic pressure, viscosity,
Principle active component content, sterile, Preservative effectiveness etc. should meet the requirements.
In the present invention, the validity period of product is 90 days behind Kaifeng.
In the present invention, each container loading amount is no less than the 97% of sign loading amount, and average loading amount is no less than sign loading amount.
In the present invention, packaging should be sealed, and must not have the phenomenon of leakage.
In the present invention, albumen clearance rate is more than control group normal saline solution.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto,
Any one skilled in the art the invention discloses technical scope in, technique according to the invention scheme and its
Inventive concept is subject to equivalent substitution or change, should all be included within the scope of the present invention.
Claims (10)
1. a kind of contact lens care solution, it is characterised in that：It is described hidden on the basis of the gross mass of the contact lens care solution
Shape eye care liquid is made up of following each component：
Hydroxypropyl methylcellulose 1.3mg/ml；
Poloxamer 2mg/ml；
Natrium adetate 1mg/ml；
Poly hexamethylene biguanide 0.0018mg/ml；
Propane diols 2mg/ml.
2. a kind of contact lens care solution according to claim 1, it is characterised in that：The sign of the hydroxypropyl methylcellulose
Measure as 1.3mg/ml, the franchise of the hydroxypropyl methylcellulose is ± 20%.
3. a kind of contact lens care solution according to claim 1, it is characterised in that：The labelled amount of the poloxamer
2mg/ml, the franchise of the poloxamer is ± 20%.
4. a kind of contact lens care solution according to claim 1, it is characterised in that：The labelled amount of the natrium adetate
For 1mg/ml, the franchise of the natrium adetate is ± 20%.
5. a kind of contact lens care solution according to claim 1, it is characterised in that：The mark of the poly hexamethylene biguanide
The amount of showing is 0.0018mg/ml, and the franchise of the poly hexamethylene biguanide is ± 20%.
6. a kind of contact lens care solution according to claim 1, it is characterised in that：The labelled amount 2mg/ of the propane diols
Ml, the franchise of the propane diols is ± 20%.
7. a kind of contact lens care solution according to claim 1, it is characterised in that：The pH of the contact lens care solution
It is worth for 6.5-7.8.
8. a kind of contact lens care solution according to claim 1, it is characterised in that：The contact lens care solution oozes
Pressure is 260-340mOsm/kgH thoroughly2O。
9. a kind of contact lens care solution according to claim 1, it is characterised in that：The contact lens care solution it is glutinous
Spend for 1-5mPas.
10. a kind of contact lens care solution according to claim 1, it is characterised in that：The contact lens care solution
Preparation method is following steps：
A, by hydroxypropyl methylcellulose in 80 ° of hot water disperse, add cold water hot-cold lysis；
B, will natrium adetate, boric acid, borax, sodium chloride, poloxamer and propane diols add pure water in dissolve；
C, two kinds of solution in step A and step B are well mixed；
D, poly hexamethylene biguanide added in the solution in step C, stirred；
E, the solution for obtaining step D are filtered through 0.45 μm and 0.22 μm of polyether sulfone sterilizing filter successively, the feed liquid after filtering
It is directly placed into sterilized plastic bottle, jumps a queue, covers sealing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710475736.8A CN107201277A (en) | 2017-06-21 | 2017-06-21 | A kind of contact lens care solution |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710475736.8A CN107201277A (en) | 2017-06-21 | 2017-06-21 | A kind of contact lens care solution |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107201277A true CN107201277A (en) | 2017-09-26 |
Family
ID=59907854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710475736.8A Pending CN107201277A (en) | 2017-06-21 | 2017-06-21 | A kind of contact lens care solution |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107201277A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108102803A (en) * | 2017-12-24 | 2018-06-01 | 洛阳名力科技开发有限公司 | A kind of contact lenses multifunction nursing liquid |
| CN108148683A (en) * | 2017-12-24 | 2018-06-12 | 洛阳名力科技开发有限公司 | contact lens care solution |
| CN109439469A (en) * | 2018-12-27 | 2019-03-08 | 江苏海伦隐形眼镜有限公司 | A kind of dissolving method of cellulose, cellulose-containing clear transparent solutions and its application |
| CN110819464A (en) * | 2019-10-11 | 2020-02-21 | 陕西仁康药业有限公司 | Hard corneal contact lens care solution and preparation method thereof |
| JP2023537744A (en) * | 2020-08-10 | 2023-09-05 | ボシュ ＋ ロム アイルランド リミテッド | packaging solution |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1732021A (en) * | 2002-11-18 | 2006-02-08 | 眼力健有限公司 | Multifunctional contact lens care composition comprising propylene glycol or glycerol |
| CN1818048A (en) * | 2006-03-21 | 2006-08-16 | 侯丽君 | Cleaning fluid composition for contact lens, its use and method |
| CN101524554A (en) * | 2009-04-08 | 2009-09-09 | 上海卫康光学有限公司 | Composition used with contact lens for cleaning and disinfection and application thereof |
| CN101574537A (en) * | 2009-06-01 | 2009-11-11 | 海昌隐形眼镜有限公司 | Composition for contact lens solution containing peppermint and preparation method thereof |
| CN101790694A (en) * | 2007-08-31 | 2010-07-28 | 诺瓦提斯公司 | Contact lens product |
| CN102959458A (en) * | 2010-07-06 | 2013-03-06 | 日本乐敦制药株式会社 | Composition for contact lens care |
| CN106867704A (en) * | 2017-01-25 | 2017-06-20 | 东南大学 | A kind of contact lens care solution containing the double cleaning systems of sucrose ester |
-
2017
- 2017-06-21 CN CN201710475736.8A patent/CN107201277A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1732021A (en) * | 2002-11-18 | 2006-02-08 | 眼力健有限公司 | Multifunctional contact lens care composition comprising propylene glycol or glycerol |
| CN1818048A (en) * | 2006-03-21 | 2006-08-16 | 侯丽君 | Cleaning fluid composition for contact lens, its use and method |
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