CN107137057A - A kind of anterior ocular segment OCT image device and method - Google Patents
A kind of anterior ocular segment OCT image device and method Download PDFInfo
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Abstract
本发明公开了一种眼前节OCT成像装置及方法,该装置包括:光源、分线器、样品臂、参考臂和信号处理器,分线器与信号处理器连接,样品臂包括第一准直透镜、扫描振镜、电动转轮架、扫描透镜和检眼镜,所述扫描振镜包括X扫描振镜和Y扫描振镜,光源发出的光束经过分线器后分成样品臂光束和参考臂光束;电动轮转架控制样品臂光束在消色差透镜和二向色镜之间切换,分别实现对眼前节和眼后节的实时成像;参考臂光束进入参考臂后反射回分线器。本发明的眼前节OCT成像装置及方法通过在样品臂光路中加入电动转轮架,电动转轮架控制样品臂光路在消色差透镜和二向色镜之间切换,分别实现对眼前节和眼后节的测试,结构更加简单,操作起来更加。
The invention discloses an anterior segment OCT imaging device and method. The device comprises: a light source, a line splitter, a sample arm, a reference arm and a signal processor, the line splitter is connected with the signal processor, and the sample arm includes a first collimator Lens, scanning galvanometer, motorized turret, scanning lens and ophthalmoscope. The scanning galvanometer includes X scanning galvanometer and Y scanning galvanometer. The light beam emitted by the light source is divided into sample arm beam and reference arm beam after passing through the splitter ; The electric turret controls the beam of the sample arm to switch between the achromatic lens and the dichroic mirror to realize real-time imaging of the anterior segment and the posterior segment of the eye respectively; the beam of the reference arm enters the reference arm and is reflected back to the splitter. The OCT imaging device and method of the anterior segment of the present invention add an electric runner frame to the optical path of the sample arm, and the electric wheel frame controls the optical path of the sample arm to switch between the achromatic lens and the dichroic mirror, respectively realizing the imaging of the anterior segment and the eye. The test in the latter section has a simpler structure and easier operation.
Description
技术领域technical field
本发明涉及医疗成像技术领域,尤其涉及一种眼前节OCT成像装置及方法。The invention relates to the technical field of medical imaging, in particular to an anterior segment OCT imaging device and method.
背景技术Background technique
OCT又叫光学相关断层扫描,是近十年迅速发展起来的一种成像技术,它利用弱相干光干涉仪的基本原理,检测生物组织不同深度层面对入射弱相干光的背向反射或几次散射信号,通过扫描,可得到生物组织二维或三维结构图像。现有的眼前节OCT成像装置在进行扫描时,需要切换OCT主扫描光路,或者在OCT前方另外添加透镜,操作复杂,占用较多空间。OCT, also known as optical correlation tomography, is an imaging technology developed rapidly in the past decade. It uses the basic principle of weakly coherent light interferometer to detect the back reflection or several times of incident weakly coherent light at different depths of biological tissue. Scattering signals can be scanned to obtain two-dimensional or three-dimensional structural images of biological tissues. When the existing anterior segment OCT imaging device scans, it is necessary to switch the main scanning optical path of the OCT, or add an additional lens in front of the OCT, which is complicated to operate and takes up a lot of space.
发明内容Contents of the invention
针对现有技术的不足,本发明目的之一在于提供一种结构简单、操作简单且节省空间的眼前节OCT成像装置。In view of the deficiencies of the prior art, one of the objectives of the present invention is to provide an anterior segment OCT imaging device with simple structure, simple operation and space saving.
本发明的目的之二在于提供一种无需切换整个样品臂光路、操作简单的眼前节OCT成像方法。The second object of the present invention is to provide an anterior segment OCT imaging method that does not need to switch the optical path of the entire sample arm and is easy to operate.
本发明的目的之一采用如下技术方案实现:One of purpose of the present invention adopts following technical scheme to realize:
一种眼前节OCT成像装置,光源、分线器、样品臂、参考臂和信号处理器,分线器与信号处理器连接,所述样品臂包括第一准直透镜、扫描振镜、电动转轮架、扫描透镜和检眼镜,所述扫描振镜包括X扫描振镜和Y扫描振镜,所述光源发出的光束经过所述分线器后分成样品臂光束和参考臂光束;An anterior segment OCT imaging device, a light source, a line splitter, a sample arm, a reference arm and a signal processor, the line splitter is connected to the signal processor, and the sample arm includes a first collimating lens, a scanning galvanometer, a motorized rotary A wheel frame, a scanning lens and an ophthalmoscope, the scanning galvanometer includes an X scanning galvanometer and a Y scanning galvanometer, and the light beam emitted by the light source is divided into a sample arm beam and a reference arm beam after passing through the line splitter;
所述样品臂光束依次通过所述第一准直透镜、所述扫描振镜、所述电动轮转架、所述扫描透镜和所述检眼镜到达人眼,接着反射回所述分线器,所述电动轮转架上设有消色差透镜和二向色镜,所述电动轮转架控制所述样品臂光束在所述消色差透镜和所述二向色镜之间切换,分别实现对眼前节和眼后节的实时成像;The light beam of the sample arm passes through the first collimating lens, the scanning galvanometer, the motorized turret, the scanning lens and the ophthalmoscope to reach the human eye, and then reflects back to the splitter, so The electric turret is provided with an achromatic lens and a dichroic mirror, and the electric turret controls the light beam of the sample arm to switch between the achromatic lens and the dichroic mirror, respectively realizing the anterior segment and the dichroic mirror. Real-time imaging of the posterior segment of the eye;
所述参考臂光束进入所述参考臂后反射回所述分线器。The light beam of the reference arm enters the reference arm and is reflected back to the splitter.
进一步地,所述参考臂包括第二准直透镜和反光镜,所述参考臂光束经过所述第二准直透镜后准直,接着经过所述反光镜后反射回所述分线器。Further, the reference arm includes a second collimator lens and a reflector, and the light beam of the reference arm is collimated after passing through the second collimator lens, and then reflected back to the splitter after passing through the reflector.
进一步地,所述检眼镜为双面偶次非球面透镜。Further, the ophthalmoscope is a double-sided even-order aspheric lens.
本发明的目的之二采用以下技术方案实现:Two of the purpose of the present invention adopts following technical scheme to realize:
一种眼前节OCT成像方法,包括:An anterior segment OCT imaging method, comprising:
光源发出的光束经过分线器后分成样品臂光束和参考臂光束,样品臂光束进入样品臂,参考臂光束进入参考臂;The light beam emitted by the light source is divided into the sample arm beam and the reference arm beam after passing through the splitter, the sample arm beam enters the sample arm, and the reference arm beam enters the reference arm;
所述样品臂中的电动轮转架控制样品臂光束在消色差透镜和二向色镜之间切换,分别实现对眼前节和眼后节的成像;The electric turret in the sample arm controls the light beam of the sample arm to switch between the achromatic lens and the dichroic mirror, respectively realizing the imaging of the anterior segment and the posterior segment;
所述样品臂光束成像后反射回所述分线器;The light beam of the sample arm is reflected back to the splitter after imaging;
所述参考臂光束进入所述参考臂后反射回所述分线器;The light beam of the reference arm enters the reference arm and is reflected back to the splitter;
反射回的样品臂光束和参考臂光束发生干涉;The reflected sample arm beam interferes with the reference arm beam;
信号处理器对干涉信息处理后实现OCT成像。The signal processor realizes OCT imaging after processing the interference information.
进一步地,所述电动轮转架控制样品臂光束在消色差透镜和二向色镜之间切换,分别实现对眼前节和眼后节的实时成像,具体包括:Further, the electric turret controls the light beam of the sample arm to switch between the achromatic lens and the dichroic mirror, respectively realizing real-time imaging of the anterior segment and the posterior segment, specifically including:
当测试眼前节时,所述样品臂中的电动转轮架将样品臂光束切换至所述消色差透镜,当测试眼后节时,所述样品臂中的电动转轮架将样品臂光束切换至所述二向色镜。When testing the anterior segment, the motorized turret in the sample arm switches the sample arm beam to the achromatic lens, and when testing the posterior segment, the motorized turret in the sample arm switches the sample arm beam to the dichroic mirror.
进一步地,所述参考臂包括第二准直透镜和反光镜,参考臂光束经过所述第二准直透镜后准直,接着经过所述反光镜后反射回分线器。Further, the reference arm includes a second collimating lens and a reflector, and the beam of the reference arm is collimated after passing through the second collimating lens, and then reflected back to the splitter after passing through the reflector.
相比于现有技术,本发明的有益效果在于:在样品臂光路中加入电动转轮架,通过电动转轮架控制样品臂光路在消色差透镜和二向色镜之间切换,分别实现对眼前节和眼后节的测试,无需切换整个样品臂光路,或者在OCT前方另外添加透镜,结构更加简单,操作起来更加方便,减少了占用空间,提高工作效率。Compared with the prior art, the beneficial effect of the present invention is that: an electric turret is added to the optical path of the sample arm, and the optical path of the sample arm is controlled by the electric turret to switch between the achromatic lens and the dichroic mirror, respectively. For the test of the anterior segment and the posterior segment, there is no need to switch the optical path of the entire sample arm, or add an additional lens in front of the OCT. The structure is simpler, the operation is more convenient, the space occupied is reduced, and the work efficiency is improved.
上述说明仅是本发明技术方案的概述,为了能够更清楚了解本发明的技术手段,而可依照说明书的内容予以实施,并且为了让本发明的上述和其他目的、特征和优点能够更明显易懂,以下特举较佳实施例,并配合附图,详细说明如下。The above description is only an overview of the technical solution of the present invention. In order to better understand the technical means of the present invention, it can be implemented according to the contents of the description, and in order to make the above and other purposes, features and advantages of the present invention more obvious and understandable , the following preferred embodiments are specifically cited below, and are described in detail as follows in conjunction with the accompanying drawings.
附图说明Description of drawings
图1是本发明实施例中眼前节OCT成像装置示意图;1 is a schematic diagram of an anterior segment OCT imaging device in an embodiment of the present invention;
图2是本发明实施例中电动转轮架示意图;Fig. 2 is a schematic diagram of an electric runner frame in an embodiment of the present invention;
图3是本发明实施例中眼前节OCT成像方法示意图。Fig. 3 is a schematic diagram of an anterior segment OCT imaging method in an embodiment of the present invention.
图中:10、光源;20、分线器;30、样品臂;31、第一准直透镜;32、扫描振镜;33、电动轮转架;331、消色差透镜;332、二向色镜;34、扫描透镜;35、检眼镜;36、人眼;40、参考臂;41、第二准直透镜;42、反光镜;50、信号处理器。In the figure: 10, light source; 20, splitter; 30, sample arm; 31, first collimating lens; 32, scanning galvanometer; 33, electric wheel turret; 331, achromatic lens; 332, dichroic mirror ; 34, scanning lens; 35, ophthalmoscope; 36, human eye; 40, reference arm; 41, second collimating lens; 42, mirror; 50, signal processor.
具体实施方式detailed description
下面,结合附图以及具体实施方式,对本发明做进一步描述:Below, in conjunction with accompanying drawing and specific embodiment, the present invention is described further:
如图1-2所示,为本发明实施例中眼前节OCT成像装置,包括光源10、分线器20、样品臂30、参考臂40和信号处理器50,分线器20与信号处理器50连接,样品臂30包括第一准直透镜31、扫描振镜32、电动转轮架33、扫描透镜34和检眼镜35,扫描振镜32包括X扫描振镜和Y扫描振镜,电动轮转架33上设有消色差透镜331和二向色镜332,参考臂40包括第二准直透镜41和反光镜42,光源10发出的光束经过分线器20后分成样品臂光束和参考臂光束。As shown in Figure 1-2, it is an anterior segment OCT imaging device in the embodiment of the present invention, including light source 10, line splitter 20, sample arm 30, reference arm 40 and signal processor 50, line splitter 20 and signal processor 50 connection, the sample arm 30 includes a first collimator lens 31, a scanning galvanometer 32, a motorized rotator frame 33, a scanning lens 34 and an ophthalmoscope 35, and the scanning galvanometer 32 includes an X scanning galvanometer and a Y scanning galvanometer, and the motorized rotation The frame 33 is provided with an achromatic lens 331 and a dichroic mirror 332. The reference arm 40 includes a second collimating lens 41 and a mirror 42. The light beam emitted by the light source 10 is divided into the sample arm light beam and the reference arm light beam after passing through the line splitter 20. .
样品臂光束的光路如下:样品臂光束依次通过第一准直透镜31、扫描振镜32、电动轮转架33、扫描透镜34和检眼镜35到达人眼36,接着反射回分线器20,电动轮转架33控制样品臂光束在消色差透镜331和二向色镜332之间切换,其中,当测试眼前节时,电动转轮架33将样品臂光束切换至消色差透镜331,当测试眼后节时,电动转轮架33将样品臂光束切换至二向色镜332,分别实现对眼前节和眼后节的实时成像;The optical path of the beam of the sample arm is as follows: the beam of the sample arm passes through the first collimating lens 31, the scanning galvanometer 32, the motorized turret 33, the scanning lens 34 and the ophthalmoscope 35 to reach the human eye 36, and then reflects back to the splitter 20, and the motorized rotatable The frame 33 controls the sample arm beam to switch between the achromatic lens 331 and the dichroic mirror 332, wherein, when testing the anterior segment, the motorized rotator frame 33 switches the sample arm beam to the achromatic lens 331, and when testing the posterior segment of the eye , the motorized turret 33 switches the light beam of the sample arm to the dichroic mirror 332 to realize real-time imaging of the anterior segment and the posterior segment respectively;
参考臂光束的光路如下:参考臂光束经过第二准直透镜41后准直,接着经过反光镜42反射回分线器20;The optical path of the reference arm beam is as follows: the reference arm beam is collimated after passing through the second collimating lens 41, and then reflected back to the splitter 20 through the mirror 42;
反射回的样品臂光束和参考臂光束发生干涉,信号处理器50对干涉信息处理后实现OCT成像。The reflected beam of the sample arm interferes with the beam of the reference arm, and the signal processor 50 processes the interference information to realize OCT imaging.
作为进一步的实施方式,检眼镜35为双面偶次非球面透镜,使样品臂光束的扫描光路焦平面为弧面聚焦,更贴近人眼的生理结构,更加清晰。As a further embodiment, the ophthalmoscope 35 is a double-sided even-order aspheric lens, which makes the focal plane of the scanning optical path of the beam of the sample arm arc focused, which is closer to the physiological structure of the human eye and clearer.
如图3所示,为本发明实施例中眼前节OCT成像方法,包括:As shown in Figure 3, it is an anterior segment OCT imaging method in an embodiment of the present invention, including:
步骤10、光源发出的光束经过分线器后分成样品臂光束和参考臂光束,样品臂光束进入样品臂,参考臂光束进入参考臂;Step 10, the light beam emitted by the light source is divided into the sample arm beam and the reference arm beam after passing through the splitter, the sample arm beam enters the sample arm, and the reference arm beam enters the reference arm;
其中,样品臂包括第一准直透镜、扫描振镜、电动转轮架、扫描透镜和检眼镜,参考臂包括第二准直透镜和反光镜。Wherein, the sample arm includes a first collimating lens, a scanning galvanometer, a motorized turret, a scanning lens and an ophthalmoscope, and the reference arm includes a second collimating lens and a mirror.
步骤20、样品臂中的电动轮转架控制样品臂光束在消色差透镜和二向色镜之间切换,分别实现对眼前节和眼后节的测试;Step 20, the electric turret in the sample arm controls the light beam of the sample arm to switch between the achromatic lens and the dichroic mirror, respectively realizing the test on the anterior segment and the posterior segment;
具体的,样品臂光束依次通过第一准直透镜、扫描振镜、电动轮转架、扫描透镜和检眼镜到达人眼,扫描振镜包括X扫描振镜和Y扫描振镜,电动转轮架上设有消色差透镜和二向色镜,当测试眼前节时,样品臂中的电动转轮架将样品臂光束切换至消色差透镜,当测试眼后节时,样品臂中的电动转轮架将样品臂光束切换至二向色镜。Specifically, the light beam of the sample arm passes through the first collimator lens, the scanning galvanometer, the motorized turret, the scanning lens and the ophthalmoscope to reach the human eye in sequence. The scanning galvanometer includes the X scanning galvanometer and the Y scanning galvanometer, and Equipped with an achromatic lens and a dichroic mirror, when testing the anterior segment, the motorized turret in the sample arm switches the beam of the sample arm to the achromatic lens, and when testing the posterior segment, the motorized rotator in the sample arm Switch the sample arm beam to the dichroic mirror.
步骤30、样品臂光束测试后反射回分线器;Step 30, the light beam of the sample arm is reflected back to the splitter after the test;
步骤40、参考臂光束进入参考臂后反射回分线器;Step 40, the light beam of the reference arm enters the reference arm and is reflected back to the splitter;
具体的,参考臂光束经过第二准直透镜后准直,接着经过反光镜后反射回分线器。Specifically, the light beam of the reference arm is collimated after passing through the second collimating lens, and then reflected back to the splitter after passing through the mirror.
步骤50、反射回的样品臂光束和参考臂光束发生干涉;Step 50, interference occurs between the reflected beam of the sample arm and the beam of the reference arm;
步骤60、信号处理器对干涉信息处理后实现OCT成像。Step 60, the signal processor processes the interference information to realize OCT imaging.
作为进一步的实施方式,检眼镜为双面偶次非球面透镜,使样品臂光束的扫描光路焦平面为弧面聚焦,更贴近人眼的生理结构,更加清晰。As a further embodiment, the ophthalmoscope is a double-sided even-order aspheric lens, so that the focal plane of the scanning optical path of the beam of the sample arm is focused on a curved surface, which is closer to the physiological structure of the human eye and clearer.
相比于现有技术,本发明的有益效果在于:在样品臂光路中加入电动转轮架,通过电动转轮架控制样品臂光路在消色差透镜和二向色镜之间切换,分别实现对眼前节和眼后节的测试,无需切换整个样品臂光路,或者在OCT前方另外添加透镜,结构更加简单,操作起来更加方便,减少了占用空间,提高工作效率。Compared with the prior art, the beneficial effect of the present invention is that: an electric turret is added to the optical path of the sample arm, and the optical path of the sample arm is controlled by the electric turret to switch between the achromatic lens and the dichroic mirror, respectively. For the test of the anterior segment and the posterior segment, there is no need to switch the optical path of the entire sample arm, or add an additional lens in front of the OCT. The structure is simpler, the operation is more convenient, the space occupied is reduced, and the work efficiency is improved.
上述实施方式仅为本发明的优选实施方式,不能以此来限定本发明保护的范围,本领域的技术人员在本发明的基础上所做的任何非实质性的变化及替换均属于本发明所要求保护的范围。The above-mentioned embodiment is only a preferred embodiment of the present invention, and cannot be used to limit the protection scope of the present invention. Any insubstantial changes and substitutions made by those skilled in the art on the basis of the present invention belong to the scope of the present invention. Scope of protection claimed.
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