CN107106254A - The biopsy marker of spring ejection - Google Patents
The biopsy marker of spring ejection Download PDFInfo
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- CN107106254A CN107106254A CN201580071997.2A CN201580071997A CN107106254A CN 107106254 A CN107106254 A CN 107106254A CN 201580071997 A CN201580071997 A CN 201580071997A CN 107106254 A CN107106254 A CN 107106254A
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- marker
- delivery device
- sleeve pipe
- pipe
- biopsy
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/03—Automatic limiting or abutting means, e.g. for safety
- A61B2090/033—Abutting means, stops, e.g. abutting on tissue or skin
- A61B2090/034—Abutting means, stops, e.g. abutting on tissue or skin abutting on parts of the device itself
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3966—Radiopaque markers visible in an X-ray image
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3987—Applicators for implanting markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Surgical Instruments (AREA)
Abstract
A kind of device for the tissue for being used to insert label at biopsy site, including the slender axles jointly moved with plunger, and it is fastened to the spring of the distal end of the axle.The device can include the sleeve pipe for being configured to receive the distal end of the axle, and described sleeve pipe carries fold, depression or the further feature formed close to the distal end of the axle.Sleeve pipe can include sidewise hole, and label can be ejected from the chamber of sleeve pipe at the sidewise hole.The ramp portion connected with the sidewise hole can be formed, and the ramp portion can include the pre-selection gradient of the angle of control label ejection.
Description
The cross reference of related application
This application claims entitled " the SPRING-EJECTED BIOPSY MARKER (springs submitted on November 6th, 2014
The biopsy marker of ejection) ", the U.S. Patent application of Application No. 14/534,952 and the mark submitted on March 18th, 2015
Entitled " Biopsy Marker Delivery Device (biopsy marker delivery device) ", Application No. 62/134,715
The rights and interests of U.S. Provisional Application, the full content of two documents is expressly incorporated into herein.
Technical field
Present disclose relates generally to the device of biopsy marker is inserted at biopsy site.Especially, this disclosure relates to one
Device is planted, it uses spring to eject label into tissue from the sidewise hole of the device.
Background technology
Biopsy sample is obtained in many ways in different medical program using a variety of devices.Can be fixed in solid
Position guiding, ultrasonic guidance, magnetic resonance imaging (MRI) guiding, positron emission mammography (PEM) guiding, thymus-specific gal
Biopsy device is used under agate imaging (BSGI) guiding or other guiding.For example, some biopsy devices can be completely sharp by user
Insert to capture one or more biopsy samples at patient with one-handed performance, and by single.In addition, some biopsy devices
It can be tethered in vacuum module and/or control module, such as be used to connecting fluid (for example, compressed air, salt solution, air, true
It is empty) connection, transmission energy, and/or pass on instruction etc..Other biopsy devices can be it is completely or at least partially exercisable,
Without being fastened or being connected otherwise with another device.
Merely illustrative example of biopsy device and biopsy syste part is disclosed in U.S. Patent No. 5,526,822, entitled
" Method and Apparatus for Automated Biopsy and Collection of Soft Tissue ",
On June 18th, 1996 Granted publication；U.S. Patent No. 5,928,164, entitled " Apparatus for Automated
Biopsy and Collection of Soft Tissue ", on July 27th, 1999 Granted publication；U.S. Patent No. 6,017,
No. 316, entitled " Vacuum Control System and Method for Automated Biopsy Device ", 2000
On January 25, Granted publication；U.S. Patent No. 6,086,544, entitled " Control Apparatus for an
Automated Surgical Biopsy Device ", on July 11st, 2000 Granted publication；U.S. Patent No. 6,626,849
Number, entitled " MRI Compatible Surgical Biopsy Device ", the Granted publication on the 11st of September in 2003；United States Patent (USP)
7th, 442, No. 171, entitled " Remote Thumbwheel for a Surgical Biopsy Device ", in October, 2008
Granted publication on the 8th；U.S. Patent No. 7,648,466, entitled " Manually Rotatable Piercer ", in January, 2010
Granted publication on the 19th；U.S. Patent No. 7,854,706, entitled " Clutch and Valving System for
Tetherless Biopsy Device ", on December 1st, 2010 Granted publication；U.S. Patent No. 7,938,786, it is entitled
" Vacuum Timing Algorithm for Biopsy Device ", on May 10th, 2011 Granted publication；U.S. Patent No.
8,118, No. 755, entitled " Biopsy Sample Storage ", on 2 21st, 2012 Granted publications；U.S. Patent No. 8,
206, No. 316, entitled " Tetherless Biopsy Device with Reusable Portion ", on June 26th, 2012
Granted publication；U.S. Patent No. 8,241,226, entitled " Biopsy Device with Rotatable Tissue
Sample Holder ", the Granted publication on the 14th of August in 2011；With U.S. Patent No. 8,702,623, entitled " Biopsy
Device with Discrete Tissue Chambers ", on April 22nd, 2014 Granted publication.Above-mentioned each United States Patent (USP)
Disclosure be hereby incorporated herein by.
Other examples biopsy device and biopsy syste part are disclosed in U.S. Patent Publication the 2008/0146962nd, topic
For " Biopsy System with Vacuum Control Module ", on June 19th, 2008 announces；U.S. Patent Publication
No. 2008/0214955, entitled " Presentation of Biopsy Sample by Biopsy Device ", in September, 2008
Announce within 4th；U.S. Patent Publication the 2013/0041256th, entitled " Access Chamber and Markers for
Biopsy Device ", are announced on 2 14th, 2013；U.S. Patent Publication the 2013/0053724th, entitled " Biopsy
Device Tissue Sample Holder with Bulk Chamber and Pathology Chamber ", 2013 2
The moon 28 was announced；U.S. Patent Publication the 2013/0150751st, entitled " Biopsy Device With Slide-In
Probe ", on June 13rd, 2013 announces；U.S. Patent Publication the 2013/0324882nd, entitled " Control for Biopsy
Device ", on December 5th, 2013 announces；With U.S. Patent Publication the 2014/0039343rd, it is entitled " Biopsy System ",
Announce within 2 6th, 2014.The disclosure of above-mentioned each U.S. Patent Application Publication is hereby incorporated herein by.
In some cases, it may be desirable to mark the position of biopsy site for future reference.For example, can be from biopsy portion
One or more labels are placed at biopsy site by position before, during or after obtaining tissue samples.Exemplary indicia thing
Deployment tool includes the MAMMOMARK from Devicor Medical Products, Inc.of Cincinnati, OhioTM、And CORMARKTMBrand device.For marking the other examples apparatus and method of biopsy site to be disclosed in U.S.
State discloses No. 2009/0209854, and entitled " Biopsy Method ", August is announced on the 20th within 2009；U.S. Publication the 2009/th
No. 0270725, entitled " Devices Useful in Imaging ", on October 29th, 2009 announces；U.S. Publication the 2010/th
No. 0049084, entitled " Biopsy Marker Delivery Device ", are announced on 2 25th, 2010；U.S. Publication
No. 2011/0071423, it is entitled " Flexible Biopsy Marker Delivery Device ", on March 24th, 2011 public affairs
Cloth；U.S. Publication the 2011/0071424th, entitled " Biopsy Marker Delivery Device ", on March 24th, 2011
It is open；U.S. Publication the 2011/0071391st, entitled " Biopsy Marker Delivery Device with
Positioning Component ", on March 24th, 2011 announces；U.S. Patent No. 6,228,055, entitled " Devices
For Marking and Defining Particular Locations in Body Tissue ", are awarded on May 8th, 2001
Power bulletin；U.S. Patent No. 6,371,904, entitled " Subcutaneous Cavity Marking Device and
Method ", on April 16th, 2002 Granted publication；U.S. Patent No. 6,993,375, entitled " Tissue Site Markers
For In Vivo Imaging ", on January 31st, 2006 Granted publication；U.S. Patent No. 6,996,433, it is entitled
" Imageable Biopsy Site Marker ", on 2 7th, 2006 Granted publications；U.S. Patent No. 7,044,957, topic
For " Devices for Defining and Marking Tissue ", on May 16th, 2006 Granted publication；U.S. Patent No.
7,047, No. 063, entitled " Tissue Site Markers for In Vivo Imaging ", on May 16th, 2006 authorizes public
Accuse；U.S. Patent No. 7,229,417, entitled " Methods for Marking a Biopsy Site ", June 12 in 2007
Day Granted publication；With U.S. Patent No. 7,465,279, entitled " Marker Device and Method of Deploying
A Cavity marker Using a Surgical Biopsy Device ", on December 16th, 2008 Granted publication.Above-mentioned U.S.
The disclosure of each in state's patent and U.S. Patent Application Publication is hereby incorporated herein by.
The content of the invention
It is related to device and system, and the method for manufacturing and using described device and system in terms of the disclosure.The dress
Put includes push rod (such as plunger and/or axle), pipe or other sleeve pipes, ramp portion, sidewise hole with system, and in the axle
At least a portion on the spring that extends.According to some aspects of the disclosure, device can be configured to when using it every time, with
Same amount of power ejects label.In certain aspects, the present apparatus can be grasped independent of any power applied by user
Make, and ensure as one man, repeatably to place the label.
Attendant advantages and novel feature in terms of these will be set forth in part in the description that follows, and part is for this
It will be become readily apparent from or recognized by the practice of the disclosure by following examination for art personnel.
Brief description of the drawings
Fig. 1 describes the stereogram of the exemplary indicia thing conveying device of the aspect according to the disclosure.
Fig. 2 describes the sectional view of the distal end of marker delivery device, and the wherein section is intercepted along the line 2-2 in Fig. 1.
The side view of the distal end of the axle of marker delivery device in Fig. 3 A depictions 1.
The partial section of the distal end of marker delivery device in Fig. 3 B depictions 1, its axis and spring are initial
Proximal position.
The partial section of the distal end of marker delivery device in Fig. 3 C depictions 1, its axis and spring section to
It is distally advanced.
The partial section of the distal end of marker delivery device in Fig. 3 D depictions 1, its axis and spring fully to
It is distally advanced.
The sectional view of the sleeve pipe of marker delivery device in Fig. 4 depictions 1, the wherein section are cut along the line 4-4 in Fig. 2
Take.
Fig. 5 describes the stereogram of the exemplary indicia thing for the marker delivery device in Fig. 1.
Fig. 6 describes the stereogram of another exemplary indicia thing for the marker delivery device in Fig. 1.
Fig. 7 describes the stereogram of another the exemplary indicia thing for the marker delivery device in Fig. 1.
Fig. 8 describes the stereogram of the exemplary replacement sleeve pipe for the marker delivery device in Fig. 1.
The sectional view of sleeve pipe in Fig. 9 depictions 8, the wherein section are intercepted along the line 9-9 in Fig. 8.
Figure 10 describes the stereogram of the exemplary surrogate markers thing conveying device of the aspect according to the disclosure.
Figure 11 A describe the side view of the marker delivery device in Fig. 9, and wherein plunger is in non-activation point.
Figure 11 B describe another side view of the marker delivery device in Fig. 9, and wherein plunger drives position in part
Put.
Figure 11 C describe another side view of the marker delivery device in Fig. 9, and wherein plunger is in driving position completely
Put.
Figure 12 describes the stereogram of another exemplary surrogate markers thing conveying device of the aspect according to the disclosure.
The sectional view of marker delivery device in Figure 13 depictions 12, the wherein section are cut along the line 13-13 in Figure 12
Take.
The end-view of the sleeve pipe of marker delivery device in Figure 14 depictions 12.
Figure 15 describes another exemplary stereogram for substituting sleeve pipe for the marker delivery device in Fig. 1.
The sectional view of sleeve pipe in Figure 16 depictions 15, the wherein section are intercepted along the line 16-16 in Figure 15.
Figure 17 A describe the side view of the various features with the exemplary means for departing from part of the aspect according to the disclosure
Figure, to show that the length of structure can be the length of any pre-selection.
Figure 17 B describe along the longitdinal cross-section diagram intercepted along 1B-1B in Figure 17 A.
Figure 17 C are depicted in the enlarged drawing of the distal end of structure depicted in Figure 17 B.
Figure 17 D describe alternative aspect, wherein depression replaces the annular fold in Figure 1A.
Figure 18 A roughly describe the one side of the present apparatus with side view.
Figure 18 B are depicted in longitudinal side cross-sectional, view of Figure 18 A structure depicteds.
Figure 18 C are depicted in longitudinal top cross-sectional view of Figure 18 A structure depicteds.
Figure 19 describes the side view of each feature of the exemplary means of the aspect according to the disclosure.
Embodiment
The following description of some examples of various aspects of the disclosure should not be taken to limit its scope.Retouched by following
State, the other examples, feature, aspect, modification and advantage of this technology be will be apparent for a person skilled in the art, and these are retouched
State and diagrammatically carry out, be to be contemplated for carrying out one of optimal mode of this technology.It will be recognized that the aspect energy of the disclosure
Enough there is other different and obvious implementation, all these implementations are all without departing from its scope.Therefore, accompanying drawing and description
It should be considered as in itself illustrative and non-limiting.
Fig. 1-Fig. 4 flag activation thing conveying devices (10), the marker delivery device (10) can be used for biopsy device or
Person's targeting group, so as to which label is transported into biopsy site.Marker delivery device (10) includes body (20) and sleeve pipe
(40).As shown in figure 1, body (20) includes thin-long casing (22), handle (24), elastic component (26) and plunger (28).Shell
Body (20) is connected to sleeve pipe (40) by body (22).In addition, housing (22) can close the other of marker delivery device (10)
Functional unit, such as seal, spring, bushing, or in view of the teachings contained herein, be to those skilled in the art
Obvious other functional units.
Handle (24) is positioned in the proximal end of housing (22), and is for example configured to the finger grip by user.
As will be described in more detail below, handle (24) is generally configured to permission marker delivery device (10) and grasped by user's one hand
Make.The handle (24) of this example is integratedly constructed with housing (22).But in other examples, alternatively, handle (24) can be with
Separated with housing (22).
Elastic component (26) is arranged between handle (24) and plunger (28).Especially, the elastic component (26) of this example
Including the leaf spring with two openings (27), described two openings (27) are in the either end of elastic component (26).It is open (27)
It is configured to slideably received within axle (30).As will be described in more detail below, axle (30) is slidably relative to body (10)
, so as to optionally from marker delivery device (10) ejection label (60).Although elastic component (26) is shown as leaf spring,
It is understood that in other examples, any other suitable elastic device, such as helical spring can be used.
Plunger (28) is positioned in the proximal end of axle (30).Plunger (28) is usually configured to be promoted so as to phase by user
For body (20) and sleeve pipe (40) distad actuator shaft (30).In addition, as shown, plunger (28) is against elastic component
(26) so that after user drives marker delivery device by plunger (28), elastic component (26) can make axle
(30) return to figure 1 illustrates proximal position.As will be described in more detail below, plunger (28) and handle (24) are common
Construction, for example, allow user to use two fingers (for example, forefinger and middle finger) grasping member (24), and using another
Individual finger (for example, thumb) promotes plunger (28).Although it is understood that not shown, plunger (28) can be equipped with plunger
Lock or other lock-in features, so as to allow user by plunger (28) ratchet engage or be locked in given position (for example,
Plunger (28) is locked in proximal position and/or plunger (28) is locked in distal position etc.).Suitable lock-in feature can be with
Including resilient latch hammerlock, bayonet latches feature, characteristic threads etc..
Sleeve pipe (40) is included from the distally extending elongated tubulose axle of housing (22).Sleeve pipe (40) is generally distally extending
One section be adapted for insertion into biopsy device or targeting group length so that sleeve pipe (40) extends to biopsy site to convey mark
Thing (60).In this example, the distal end of sleeve pipe (40) includes sidewise hole (42) and distal tip (44).As illustrated in fig. 1,
Sidewise hole (42) is positioned proximal to the distal end of sleeve pipe (40).As that can be understood, sidewise hole (42) is relative to sleeve pipe (40)
The ad-hoc location of distal end be constructed such that sidewise hole (42) can be aligned with the corresponding sidewise hole of the pin of biopsy device.
As can be most found out in fig. 2, distal tip (44) is cannulated the distal end of (40), and is longitudinally extended entrance
At least a portion of sidewise hole (42).The near-end of distal tip (44) includes ramp portion (46).As will be retouched in more detail below
State, ramp portion (46) is configured to label (60) of the guiding from casing cavity (48), the casing cavity (48) is longitudinally extended
Connected through sleeve pipe (40) and with sidewise hole (42).
The near-end of casing cavity (48) from sleeve pipe (40) extends to the distal end of sleeve pipe (40)., should although not shown in FIG. 2
Understand, in some instances, casing cavity (48) can extend into housing (22) so that the axle (30) of body (20) can be with
Connected with chamber.Especially, as that can find out in fig. 2, axle (30) extends through body (20) and is terminating at sleeve pipe (40)
Proximate distal ends before, in sleeve pipe (40).As will be described in more detail below, axle (30) is slidably disposed on sleeve pipe
To engage label (60) in chamber (48), so as to drive label (60) to ramp portion (46) and from sidewise hole (42)
Go out.In certain aspects, the gradient of ramp portion (46) can control the angle that label (60) is ejected from casing cavity (48).
Although the axle (30) of this example is shown as being placed coaxially in casing cavity (48), in other examples, axle (30)
It can terminate in body (20), and individually component, axle or bar can extend into casing cavity (48).
According to some aspects of the disclosure, as shown in Figure 17 A, device can include the near-end with amplification
(171) plunger (172), for example, the near-end (171) may be used as the handle for user.As shown in Figure 17 B
, the near-end (173a) of slender axles (16) can be received in the hole (172a) to be formed on plunger (172), and can be tight
Gu to thereon, so that axle (173) can be jointly mobile with plunger (172).
In this aspect of the invention, distal end of the slender casing (174) slideably received within axle (173).As shown in Figure 17 C
, according to some aspects, annular fold (174a) can be formed in its inherent proximate distal ends of sleeve pipe (174).According to some aspects,
Sleeve pipe (174) can include sidewise hole (174b), at the sidewise hole (174b) place by label (176) from sleeve pipe (174)
Intracavitary is ejected.
As can see in figure 3 a, the distal end of the axle (30) of this example includes spring (90), and the spring (90) is in axle
(30) extend at least a portion of distal end.Especially, the spring (90) of the example includes at least a portion with axle (30)
Coaxial many pitch auger springs, for example, the compression that the spring (90) is configured to every 1/10 inch produces 1.9l to 2.4 pounds
Power between power.In this example, spring (90) is made up of the stainless steel of bio-compatible, however can use it is any other suitable
Bio-compatible material.Spring (90) includes the first pitch region (92), the second pitch region (94) and the 3rd pitch region
(96).First pitch region (92) and the 3rd pitch region (96) include substantially the same pitch.It should be appreciated that herein
The term " pitch " used refers generally to the spacing between each coil of spring (90).For example, the first pitch region and the 3rd spiral shell
Pitch away from region (96) can be smaller relative to the pitch in the second pitch region (94).Term " pitch " is it can be appreciated that relate to
And the specific quantity of the coil (for example, coil of per inch) per unit axial distance.
In the first pitch region (92) of this example and the 3rd pitch region (96), between each coil of spring (90)
Spacing can be with relatively small or close to zero so that each line in the first pitch region (92) and the 3rd pitch region (96)
Circle is in contact with each other or close contact.As will be described in more detail below, at compression spring (90), such pitch can be with
Cause the compression in the first pitch region (92) and the 3rd pitch region (96) very small.However, with the first pitch region (92)
Spacing between the 3rd each coil in pitch region (96) is compared, the spring (90) in the second pitch region (94)
Spacing between each coil can be with relatively large.Therefore, when compression spring (90), relative to the first pitch region (92) and
3rd pitch region (96), the second pitch region (94) can be compressed more.Although pitch region (92,94,96) are shown
For with specific pitch, it should be appreciated that in view of the teachings contained herein, to those skilled in the art significantly
It is that each pitch region can have any suitable pitch.
The first pitch region (92) of this example and the 3rd pitch region (96) include 24 to 25 and enclosed, but the first pitch
Region (92) and the 3rd pitch region (96) can include any suitable number of turns.Although the first pitch region (92) and the 3rd spiral shell
It is configured to, at compression spring (90), relative to the second pitch region (94), be subjected to the compression of very little away from region (96), should
What is understood is that the first pitch region (92) and the 3rd pitch region (96) still can be configured to flexure unber lateral so that axle (30) is logical
, still can some lateral movements of progress in sleeve pipe (40) when crossing spring (90) and label (60) and keeping contact.From the foregoing
It is to be further understood that pitch and the first pitch region (92) and the 3rd pitch region (96) due to the second pitch region (94)
Pitch between difference, such as when spring (90) is by longitudinal compression load, such as the driving period in plunger (28),
Two pitch regions (94) can be compared with the first pitch region (92) and the second pitch region (94) (and to a greater degree) pressure first
Contracting.
According to some aspects of the disclosure, as shown in Figure 17 B and Figure 17 C, spring (20) can be fastened to axle (174)
Distal end.According to some aspects, spring can only include two pitch regions (175b and 175).In certain aspects, coil can
With the far-end for the spring being packed tightly relative to each other in pitch region (175c).According to some aspects, nearside
Pitch region (175b) can include the coil accumulated laxly.It should be appreciated that the spring with two pitch regions can
To be worked similar to the spring with three pitch regions, as will be described in more detail below.
Fig. 3 A are returned to, as will be described in more detail below, usually, spring (90) is fixedly secured to axle (30), makes
Spring (90) contact mark thing (60) first is obtained, is then compressed when axle (30) advances, finally axle (30) can be contacted
Label (60).In this example, spring (90) is shown as being fixedly secured to axle at the point of the distal end close to axle (30)
(30) so that only some first pitch region (92) is distally extending from the distal end of axle (30).Certainly, in other examples
In, any suitable part of spring (90) can extend from the distal end of axle (30).For example, the spring (90) of this example can lead to
Cross laser welding and be fixedly secured to axle (30).In other examples, axle (30) can simply include annular protrusion or many
Individual projection, projection can prevent spring (90) from being slided along axle (30) to nearside.In other other examples, axle (30) can be wrapped
Annular protrusion or multiple projections are included, projection can be configured to by press-fit or interference fit fastening spring (90).Another
In some other examples, in view of the teachings contained herein, it will be obvious to one of ordinary skill of the art that can use bullet
Spring (90) is fastened to the other suitable features or method of axle (30), for example, screw, pin or adhesive.
As shown in Figure 17 B, device can include the annular retainer with axle (173) integrally molded formation
(175a), and the near-end of spring is fastened to the axle (173), so that the spring is not slided relative to the axle.
As shown in figure 3 a, the label (60) of this example includes biodegradable or can otherwise inhaled
The body (62) of receipts.Absorbable body (62) can have a shape of substantial cylindrical, and can by collagen, hydrogel and/
Or other any suitable material compositions.Absorbable body (62) can include (for example, the titanium), generally radiopaque of metal
Labelled element (64) (being shown in phantom), the labelled element (64) is arranged in absorbable body (62), or otherwise
Carried by absorbable body (62).The labelled element (64) of this example is configured to helical spring, it should be understood that, mark
Element (64) can have any other shape for being suitable to strengthen radiography observability.It is to be further understood that metal is only
One kind can be used for the illustrated examples to form the material of labelled element (64).In view of the teachings contained herein, for this area
It is evident that various other suitable materials can be used for those of ordinary skill.
In some instances, it may be necessary to be equipped with some labels (60) for marker delivery device (10) and keep feature,
So as to which optionally label (60) is fastened in sleeve pipe (40).For example, the sleeve pipe (40) of this example is recessed including two holdings
Fall into (50), depression (50) is arranged in casing cavity (48) close to sidewise hole (42).As can be most found out in Fig. 4, it is recessed (50)
Sidewise hole (42) is may be located remotely to be arranged near the bottom of sleeve pipe (40).For example, depression (50) can be hemispherical shape, and
It is inwardly projecting in casing cavity (48).Therefore, depression (50) can be configured to engage at least a portion of label (60), so as to
Label (60) is maintained in casing cavity (48).However, because absorbable body (62) is by collagen, hydrogel and/or other
Deformable material is constituted, and label (60) can have the attribute of relative resilient so that label (60) can pass through axle (30)
Optionally it is forced through depression (50).Alternatively, label (60) can have small by one relative to the internal diameter of sleeve pipe (40)
A little size so that when axle (30) promotes label (60), label (60), which can be pushed upwardly, crosses depression (50).To the greatest extent
Pipe-in-pipe (40) is shown as including two depressions (50), it should be appreciated that in other examples, sleeve pipe (40) can include
Any other appropriate number of depression (50).
As shown in Figure 17 D, circumferentially spaced two depressions (174d) can be formed in sleeve pipe (174).
If 0 ° of position will be defined as at the top of sleeve pipe (174) as shown in figure 17d, the first depression can be positioned at close to 135 ° of positions
Place and second depression can be positioned at close at 225 ° of positions.According to some aspects, annular fold (174a) can be by substantial amounts of
The depression of tight spacing is formed.However, the preferred amount of circumferentially equally spaced depression may be as few as two, as retouch
Paint, up to eight or more.According to some aspects, if for example, selected eight depressions, can have one at 0 ° of position
Depression, hereafter every 45 ° of the circumference around sleeve pipe (174) can have a depression.
Additionally or alternatively, in addition to hemispherical shape, depression (50) can also include other shapes.For example, in view of
Teaching herein, it will be obvious to one of ordinary skill of the art that depression (50) can be pyramid, cube, water chestnut
Shape, or other any suitable shapes.As another is merely illustrative example, annular protrusion or fold can stretch into chamber
(48) in, it is used as the substitute of depression (50).Be merely illustrative at another in example, with sleeve pipe (40) monoblock type structure
The tongue piece for the relative flexibility made or contact pin can be stretched into chamber (48), be used as another substitute of depression (50).
According to some aspects, as shown in Figure 18 A to Figure 18 C, sleeve pipe (174) can include tongue piece (177), the tongue
Piece is hidden in outside the visual field in Figure 18 A side view, and in Figure 18 B longitudinal side cutaway view and Figure 18 C
Longitudinal top plan view in be visible.According to some aspects, tongue piece (177) and sleeve pipe (174) can be integrally with each other
Formed, and the tongue piece can provide for example resist by shaft-driven label (176) proximally to distal side displacement stopping
Dynamic device, i.e. tongue piece (177) can perform the function similar with annular fold described herein or depression.According to some aspects,
For example, when label (176) is formed by non-flexible and non-elastic material, this tongue piece (177) can be used.
As shown in figure 19, according to some aspects, protuberance can be formed in casing cavity (174) or is heaved (26), the drum
Rise and perform the function similar with tongue piece (177).For example, bulging (178) and tongue piece (177) can be configured to work as rigid markers' thing
(176) flattened when being pushed over these features.
Fig. 3 B to Fig. 3 D show exemplary the using of marker delivery device (10).As can be seen that mark such as from Fig. 3 B
Note thing (60) is originally arranged in casing cavity (42) close to depression (50).Then user can be by sleeve pipe (40) insertion biopsy dress
Put or targeting group, so that when in the tissue that biopsy device or targeting group have been positioned at biopsy site, in biopsy
Position conveying label (60).Sleeve pipe (40) may be positioned such that sidewise hole (42) in an angularly can be filled longitudinally with biopsy
Put or targeting group pin or sleeve pipe complementary sidewise hole alignment.Once sleeve pipe (40) is already inserted into biopsy device or targeting
Group and it is properly positioned wherein, for example, user can be by using one hand, or alternatively uses multiple hands, catch hand
Handle (24) and plunger depressed (28) start deployment.
When plunger (28) is distad pressed, axle (30) can relative to sleeve pipe (40) and body (20) distad before
Enter, as shown in the change between Fig. 3 B and Fig. 3 C.When the distal end of axle (30) is close to label (60), spring (90) can be with
Contact mark thing (60) first.As shown in Fig. 3 B and Fig. 3 C, when axle (30) is advanced further, this contact can be with compression spring
(90), so as to store potential energy in spring (90).
The additional advance of axle (30) can ultimately result in the direct contact between the distal end of label (60) and axle (30).Such as
In fig. 3 c it can be seen that, in this stage, the distal end that the distal end of axle (30) can be substantially with spring (90) is aligned, once
This directly to contact, axle (30) will start distad to promote label (60) in the sleeve pipe (40) so that label (60) to
Be distally advanced, by and/or cross depression (50) and gone out from sidewise hole (42).Once label (60) is away from depression (50),
Spring (90) can begin through the potential energy produced during the compression of spring (90) and uphold.As can see from Fig. 3 D,
This extension of spring (90) may finally make label (60) laterally proceed to the ramp portions (46) of distal tip (44)
On, gone out by sidewise hole (42) and enter biopsy site.It is understood that the first pitch region (92) can be in depression
(50) top is bent, and extends past depression (50).Thus, for example, the construction of spring (90) can allow spring (90) in chamber
(48) laterally deflection in so that do not need axle (30) in any deflection of intracavitary, spring (90) can be to be advanced past depression
(50).Forming the coil in the first pitch region (92) can simply slide to cross depression (50) relative to each other.Recessed
It is trapped in the modification arranged in chamber (48) along bigger angular range (such as in the sleeve pipe (640) being described below), spring
(90) it still can deform distad to surmount depression (50).For example, the coil for forming the first pitch region (92) can be relative
In sliding over each other and obliquely being tilted relative to the longitudinal axis of chamber (48), to reduce effective external diameter of spring (90), so that
The space for allowing spring (90) to be limited by being recessed between (50).
Fig. 5 shows exemplary surrogate markers thing (160), and the label (160) can be attached to or instead of above-mentioned mark
Remember thing (60) and used.The label (160) of this example is substantially similar to label (60).For example, as label (60)
Equally, label (160) can include biodegradable or otherwise absorbable body (162).It can absorb this
Body (162) has the shape of substantial cylindrical, and can be by collagen, hydrogel, and/or other any suitable material compositions.
Body (62) is can absorb as described above, and metal, usual radiopaque labelled element can be included by caning absorb body (162)
(164), the labelled element (164) is arranged in absorbable body (162), or otherwise by caning absorb body (162)
Carrying.However, unlike labelled element (64), the labelled element (164) of this example can include discoid central component (166)
(being shown in phantom), the central component (166) has to be protruded and from absorbable body radially outward from central component (166)
(162) three elongated raiseds (168) gone out.It can be used for forming labelled element it is to be further understood that metal is only one kind
(164) an illustrative example of material.In view of the teachings contained herein, to those skilled in the art significantly
It is that can use various other suitable materials.
In some instances, elongated raised (168) can radially outward be protruded from central component (166) so as to provide with
The internal friction of sleeve pipe (40).Thus, for example, elongated raised (168) can be configured to contact the inside of sleeve pipe (40).This structure
Making can be used together with or instead of depression (50), such as so that label (160) is maintained in sleeve pipe (40), so that anti-
Only label (160) is dropped out unintentionally from sleeve pipe (40).In addition, elongated raised (168) can engage the tissue at biopsy site
So that label (160) is fastened at biopsy site, so as to prevent label (160) mobile.
Fig. 6 shows another exemplary surrogate markers thing (260), and the label (260) can be attached to or instead of upper
State label (60) and used.The label (260) of this example may be largely analogous to label (60).For example, as mark
Remember thing (60) equally, label (160) can include biodegradable or otherwise absorbable body (262).
However, unlike caning absorb body (62), absorbable body (262) can include the mixture of at least two materials.For example, originally showing
The absorbable body (262) of example can include substantially of a cylindrical shape collagen center section (261), two hydrogel stage casings
Partly (263) and two collagen end sections (265).Body (62) is can absorb as described above, and absorbable body (262) can be wrapped
Metal, usual radiopaque labelled element (264) (being shown in phantom) are included, the labelled element (264) is arranged on absorbable
In body (262), or otherwise by absorbable body (262) carrying.However, unlike labelled element (64), this example
Labelled element (264) generally can be with center distort (264) rectangle, so as to be configured to strengthen labelled element (264)
Radiography observability.It can be used for the material to form labelled element (264) it is to be further understood that metal is only one kind
An illustrated examples.In view of the teachings contained herein, it will be obvious to one of ordinary skill of the art that can use each
Plant other suitable materials.
Fig. 7 shows another exemplary surrogate markers thing (360), and the label (360) can be attached to or replace
Above-mentioned label (60) and used.The label (360) of this example may be largely analogous to label (60).Such as mark
Remember that thing (60) equally label (360) can include biodegradable or otherwise absorbable body (362).So
And, unlike caning absorb body (62), absorbable body (362) can include the mixing of at least two materials.For example, this example
Absorbable body (362) can include the substantially of a cylindrical shape collagen shell (361) with hydrogel core (363).
Body (62) is can absorb as described above, and metal, usual radiopaque labelled element can be included by caning absorb body (362)
(364) (it is shown in phantom), the labelled element (364) is arranged in absorbable body (362), or otherwise by that can inhale
Receive body (362) carrying.However, unlike labelled element (64), the labelled element (364) of this example generally can be with center
Distort (364) rectangle, so as to be configured to strengthen labelled element (364) radiography observability.It is to be further understood that
Metal is only the illustrated examples that one kind can be used for forming the material of labelled element (364).In view of the teachings contained herein, it is right
It is evident that various other suitable materials can be used for those of ordinary skill in the art.
Fig. 8 and Fig. 9 show exemplary replacement sleeve pipe (440), and the sleeve pipe (440) can be merged into above-mentioned biopsy marker
Device (10).The sleeve pipe (440) of this example may be largely analogous to above-mentioned sleeve pipe (40), except it indicated in addition herein
Outside.For example, sleeve pipe (440) can include elongated tubular product axle (441), the tubulose axle (441) is included close to distal tip (444) side
To hole (442), and extend through the casing cavity (448) of sleeve pipe (440).However, unlike sleeve pipe (40), sleeve pipe (440) can be with
Including protective metal shell (452), the sheath (452) is set at least a portion of the distal tip of sleeve pipe (440).It should also manage
Solution, metal is only the illustrated examples that one kind can be used for forming the material of sheath (452).In view of this paper religion
Lead, it will be obvious to one of ordinary skill of the art that various other suitable materials can be used.Protective metal shell
(452) distal end that may be constructed to sleeve pipe (440) provides structural strengthening.For example, during sleeve pipe (40) is used, protective metal shell
(452) the distal end flexing of sleeve pipe (440) can be prevented, or is otherwise deformed.Additionally or alternatively, sleeve pipe is worked as
(440) when being formed by the material with the hardness low compared with protective metal shell (452), protective metal shell (452) can prevent sleeve pipe (440)
The edge of the relatively soft material sidewise hole that is defined biopsy needle wipe off or shave off, sleeve pipe (440) inserts the biopsy needle
In.
The sidewise hole (442) of this example is desirably integrated on both sleeve pipe (440) and protective metal shell (452).Such as Fig. 8 institutes
Show, cut out sidewise hole (442) on sleeve pipe (440) and protective metal shell (452) at a certain angle so that sleeve pipe (440) and metal
Sheath (452) is collectively forming the chamfered edge (445,454,456) of alignment.For example, protective metal shell (452) can be oblique including distal side
Trimming edge (454) and nearside chamfered edge (456).The distal side chamfered edge (454) of protective metal shell (452) can be with distal side point
Ramp portion (446) alignment of (444) is held, wherein distal side chamfered edge (454) and ramp portion (446) is with essentially similar
Angle orientation.Similarly, the nearside chamfered edge that the nearside chamfered edge (456) of protective metal shell (452) can be with sleeve pipe
(445) it is aligned, wherein proximal edges (445,456) are oriented with essentially similar angle.
Chamfered edge (445,454,456) and ramp portion (446) can be inclined at an angle, and the angle is suitable to reduce
Wound to tissue remains in that sidewise hole (442) has for sufficiently large size of the label (60) by it simultaneously.
In this example, inclination angle the inclining than nearside chamfered edge (456,445) of distal side chamfered edge (454) and ramp portion (446)
Oblique angle is steeper.Although show distal side chamfered edge (454) and ramp portion (446) and distal side chamfered edge (445,456) it
Between particular kind of relationship, it should be appreciated that be not intended to and any limitation carried out to the example that shows, and in view of the teachings contained herein,
To those skilled in the art it is understood that in other examples, each inclination angle can change.
As shown in figure 9, the distal tip (444) and axle (441) of this example are integrated.Distal tip (444) and axle (441) can
To be configured to receive protective metal shell (452) so that protective metal shell (452) provides the support to distal tip (444).In some changes
In type, protective metal shell (452) can be attached to distal tip (444) and axle (441) for example, by post forming so that distal side
Sophisticated (444) and axle (441) injection molding are into protective metal shell (452).In other examples, protective metal shell (452) can lead to
Cross adhesive bonding, mechanical fasteners or any other suitable fastening means and be simply attached to distal tip (444) and axle
(441)。
The protective metal shell (452) of this example includes the biocompatible material of metal, such as stainless steel, titanium, and/or it is any its
Its suitable metal.It is not intended to and any limitation is carried out to these examples.For example, in other examples, protective metal shell (452) can be with
Including relative to axle (441) and the relatively closely knit plastics of distal tip (444).In still other example, protective metal shell (452) can
With including ceramic material.In other example, it will be obvious to one of ordinary skill of the art that protective metal shell
(452) it can be made up of any other suitable material.
Figure 10 to Figure 11 C show exemplary surrogate markers thing conveying device (510), the marker delivery device (510)
It is similar to above-mentioned marker delivery device (10).For example, marker delivery device (510) can include body (520) and set
Manage (540).Body (520) can include thin-long casing (522), handle (524) and plunger (528).Housing (522) can be with base
Above-mentioned housing (22) is similar in sheet.However, unlike housing (22), as will be described in detail below, the housing (522) of this example can
With the additional component including being configured to provide the multiple activation points for being used for plunger (528).
Similar to above-mentioned plunger (28), the plunger (528) of this example can be positioned at the proximal end of axle (530), axle (530)
Extend longitudinally through body (520) and sleeve pipe (540).Above-mentioned plunger (28) is also similarly to, for example, the plunger of this example
(528) it can be used together with handle (524), the handle is used for singlehanded driving marker delivery device (510).However, not
Plunger (28) is same as, as will be described in detail below, the plunger (528) of this example can be configured to multiple activation points.
Sleeve pipe (540) may be largely analogous to above-mentioned sleeve pipe (40), and can include distally extending from housing (522)
Elongated tubular product axle.Usually, the length that sleeve pipe (540) can be suitably inserted into biopsy device or targeting group with distally extending one section
Degree so that sleeve pipe (540) extends to biopsy site, to be conveyed by the sidewise hole (542) close to the distal end of sleeve pipe (540)
Any one in label (60,160,260,360) described herein.
Figure 11 A to Figure 11 C show the exemplary mode of operation of marker delivery device (510).Can be with such as from Figure 11 A
See, the plunger (528) of body (520) originates in initial proximal position., can be with when plunger (528) is located at initial position
Marker delivery device (510) is inserted in biopsy device or targeting group, the sidewise hole (542) of sleeve pipe (540) is positioned
At biopsy site, for example, sidewise hole (542) can longitudinally and angularly with biopsy device or the similar side of targeting group
It is aligned to hole.
Once marker delivery device (510) is positioned in biopsy device or targeting group, user may expect by
Label (60,160,260,360) is placed at biopsy site.In order to so place label (60,160,260,360), make
User can make plunger (528) proceed to part activation point as shown in Figure 11 B.In this example, housing (522) includes each
Kind part, the various parts are constructed such that axle (530) advances, when plunger (528) proceeds to part activation point, to incite somebody to action
Label (60,160,260,360) is ejected from sidewise hole (542).
In some instances, after deployment label (60,160,260,360), it may be desirable to by sleeve pipe (540) in biopsy
Rotated in device or targeting group.For example, after deployment label (60,160,260,360), label (60,160,
260th, the sidewise hole (542) of sleeve pipe (540) can 360) be remained relatively close to so that label (60,160,260,360)
At least a portion can be entered back into sidewise hole (542).In this case, removing marker delivery device (510) may
Label (60,160,260,360) is caused to damage, because label (60,160,260,360) may be trapped in sidewise hole
(542) between biopsy device or the corresponding sidewise hole of targeting group.Therefore, marker delivery device (510) typically can be with
Be configured to optionally revoling tube (540), for example, be easy to remove sleeve pipe (540), without make label (60,160,260,
360) it is stuck between sidewise hole (542) and biopsy device or the corresponding sidewise hole of targeting group.
As shown in Figure 11 C, plunger (528) proceeds to complete activation point to start relative to body (520) revoling tube
(540).It should be appreciated that can include in order to realize this function, in housing (522) spring, lever, gear, cam or
It can assemble to cause the other machinery equipment that sleeve pipe (540) rotates.In view of the teachings contained herein, for ordinary skill people
Member for it is evident that can use various parts and feature with response to plunger (528) relative to body (520) it is complete before
And then this rotation of the sleeve pipe (540) relative to body (520) is provided.It should be appreciated that in this example, housing (522)
Preceding sections can be configured to by sleeve pipe (540) relative to body (520) rotate such as 180 °.In other examples, housing
(522) it can be configured to sleeve pipe (540) rotating any suitable angle relative to body.Only by way of example, housing
(522) can be configured to sleeve pipe (540) being rotated by 90 °, 270 ° or any other suitable radial distance.
Once plunger (528) has progressed to complete activation point with revoling tube (540), for example, can be by label
Conveying device (510) is removed from biopsy device or targeting group.Alternatively, in some instances, marker delivery device (510)
It can be equipped to dispose multiple labels (60,160,260,360).In such examples, alternatively, housing (522) can be with structure
Cause, when plunger (528) is retracted, sleeve pipe (540) to be returned into its home position, for dispose another label (60,
160、260、360).Said sequence can restart again.Although it should be appreciated that said sequence is described as including by making
Two discontinuous advances of the plunger (528) of user's driving, in other examples, alternatively, plunger (528) can be with single file
Journey mode is advanced.In this illustration, in addition to other aspects, label (60,160,260,360) can be disposed, and
Then can revoling tube (540) immediately.
Figure 12-Figure 14 shows another exemplary surrogate markers thing conveying device (610), the marker delivery device
(610) it is similar to above-mentioned marker delivery device (10).For example, marker delivery device (610) can include body (620) with
And sleeve pipe (640).Body (620) can include thin-long casing (622), handle (624) and plunger (628).Housing (622),
Handle (624) and plunger (628) may be largely analogous to above-mentioned housing (22), handle (24) and plunger (28), therefore
Each details of these parts, which will not be in, is described herein as middle repetition.
Sleeve pipe (640) can be that sleeve pipe (640) can be included from housing with above-mentioned sleeve pipe (40) substantially similar part
(522) distally extending elongated tubular product axle.Usually, as shown in Figure 12 to Figure 14, sleeve pipe (640) can be with distally extending one
Section is suitably inserted into the length of biopsy device or targeting group so that sleeve pipe (640) extends to biopsy site to convey herein
Any one in the label (60,160,260,360) of description.However, the sleeve pipe (640) of this example different from sleeve pipe (40)
Can be without sidewise hole.On the contrary, sleeve pipe (640) can include for example unlimited distal tip (644), the distal tip (644)
Connected with the casing cavity (648) for extending through sleeve pipe (640).Thus, sleeve pipe (640) can be configured to by unlimited distal side point
(644) are held longitudinally to dispose label (60).
Such as it can most find out from Figure 13 and Figure 14, sleeve pipe (640) can also include the depression (50) similar to sleeve pipe (40)
Multiple depressions (650).For example, depression (650) is generally configured to and label (60) optionally is maintained at into sleeve pipe (240)
It is interior.Depression (650) can include the hemispherical shape for being substantially similar to above-mentioned depression (50).However, with set illustrated above
(40) difference is managed, the sleeve pipe (640) of this example can include three depressions (650).As it will be seen from figure 14 that depression
(650) it can be oriented around the internal diameter of sleeve pipe (640) with equidistance.It should be appreciated that such as above-mentioned depression (50), in view of this
Text teaching, to those skilled in the art it is understood that the depression (650) of this example can include it is any
Other suitable shapes and/or construction.
Figure 15 and Figure 16 show exemplary replacement sleeve pipe (740), and the sleeve pipe (740) can be merged into above-mentioned biopsy mark
Thing device (10).The sleeve pipe (740) of this example may be largely analogous to above-mentioned sleeve pipe (40), except it indicated in addition herein
Outside.For example, the sleeve pipe (740) of this example can include elongated tubular product axle (741), the tubulose axle (741) is included close to distal side point
Hold the sidewise hole (742) of (744).Axle (741) can further limit casing cavity (748), and the casing cavity (748) extends through set
Manage (740) and connected with sidewise hole (742).It is different from sleeve pipe (40), the sidewise hole (742) of sleeve pipe (740) can have with
The tear-drop shape that sidewise hole (742) extends and broadened to nearside.Thus, for example, the distal part of sidewise hole (742) can compare side
Portions of proximal to hole (742) is narrow.It should be appreciated that in some instances, at least a portion of sidewise hole (742) is (for example
The distal part of sidewise hole (742)) there can also be slightly smaller dimension relative to above-mentioned sidewise hole (42).This size can permit
Perhaps sidewise hole (742) accommodates for example less label.
As can see from Figure 16, sleeve pipe (740) may also be distinct from that sleeve pipe (40), because distal tip (744) can
With including compound ramp portion (746).For example, distal tip (744) can include three discontinuous ramp portions (743,
745th, 747) and two relatively flats part (749,751).Ramp portion (743,745,747) is as shown in figure 16 with similar
Angle is into inclined-plane, but the special angle of each ramp portion (743,745,747) can change in other examples.Typically
Ground, ramp portion (743,745,747) can be configured to make label (not shown), and progressively deflection passes through sidewise hole (742).
This progressive deflection is desirable, for example, can prevent label from prematurely exiting sleeve pipe (740), and
Label is transported to after biopsy site, can prevent label from entering back into sidewise hole (742).
For example, flat (749,751) typically can be along the flat site of their plane parallel to sleeve pipe (740)
Longitudinal axis.Flat (749,751) can be configured to provide the spacing between ramp portion (743,745,747) and work as
Label from ramp portion (743,745,747) be moved to ramp portion (743,745,747) when, change track.For example, showing
Example property is in use, when label is distally advanced, label can be advanced on first slope part (743) first.First
Ramp portion (743) can provide a certain degree of resistance to label distal movement.Only as an example, can basis
The Granted publication on the 10th of September in 2013 it is entitled " Biopsy Marker DeliveryDevice " U.S. Patent number 8,532,
At least some descriptions in 747 construct and operate first slope part (743), and the Disclosure of U.S. patent is to quote
Mode is incorporated herein.
Once label passes through first slope part (743), label can be along the first flat (749) OK
Enter, then advanced to the angle for the angle for being roughly parallel to the second ramp portion (745) in the second ramp portion (745).The
Two ramp portions (745) can provide cam face, so as to eject label by sidewise hole (742).Second flat
(751) it can prevent label from entering back into sidewise hole (742).When sleeve pipe (740) is removed from biopsy device or targeting group,
3rd ramp portion (747) can be such that any part being likely to remain in sidewise hole (742) of label is deflected away from completely
Sidewise hole (742).It is attached to or instead of foregoing, and only as illustratively, the mark that can be announced for 18th according to Septembers in 2014
It is entitled that " at least some descriptions in Biopsy Site Marker Applier " U.S. Publication the 2014/0276037th come
Construction and operation composite slope part (746), the disclosure of the U.S. Patent Application Publication are hereby incorporated herein by.
The present invention for disposing device on biopsy marker is disclosed.However, for example, various features disclosed in figure and
Part can be used in be applied in useful device to radio isotope, such as in PEM, BSGI and using the same position of radioactivity
It is in other imaging methods of plain or other radioactive sources, such as related to imaging biopsy procedure.
Device disclosed herein is generally configured to be disposed off after being intended for single use, but can also be designed to repeatedly make
With.After forming label and disposing label insertion in device, for example, sterilizing can be carried out to biopsy device.So
Afterwards, the device can be put into packaging, for example, plastics or spy defend (TYVEK) sack by force.
Then, the biopsy device of packaging can be put into radiation field, (such as γ radiation, X-ray or high energy electron) with
To device and packaging sterilizing.Any other technology being known in the art can also be used to device sterilizing, including
But it is not limited to β or γ radiation, oxirane or steam.
Although describing aspects described herein together with illustrative aspect outlined above, no matter it is known also
It is not expect at present or possible unexpected, it is various to replace, repair at least there are the personnel of ordinary skill
Change, modification, improvement and/or substantial equivalence will become obvious.Therefore, such as set forth above, illustrative aspect is intended to explanation
Rather than limitation.In the case of without departing from spirit and scope of the present disclosure, various changes can be carried out.Therefore, the disclosure
It is intended to comprising all known or later developed replacements, modification, modification, improvement and/or substantial equivalence.
Thus, claim is not intended to by aspect limitation as shown herein, but is to fit to the language one with claim
The four corner of cause, wherein, refer to that the element of singulative is not intended to expression " one and only one ", unless specifically so old
State, but " one or more ".Those of ordinary skill in the art are known or turn into known, in entire disclosure description later
The equivalent of all 26S Proteasome Structure and Functions of the element of various aspects is expressly incorporated herein by reference, and be intended to by
It is encompassed.Moreover, any content disclosed herein is all not intended to and offers to the public, no matter this disclosure whether
It is explicitly recited in claim.Claim element should not be construed to device plus function, unless explicitly used phrase " use
In ... device " describe the claim element.
It should be appreciated that the particular order or level of disclosed process/flow chart are the explanations of illustrative methods.Base
In design preference, it should be appreciated that the particular order or level in disclosed process/flow chart can be accumulated again.Enter
One step, it can combine or ignore some features/steps.Various spies are presented with sampfe order in subsidiary claim to a method
Levy/the element of step, and be not intended to limit presented particular order or level.
Further, word " example " meaning " being used as example, example or explanation " used herein.It is described herein as
It is preferred or favourable that any aspect of " example ", which is not necessarily to be construed as compared with other side,.Unless especially state in addition,
Term " some " refers to one or more.Such as " in A, B or C at least one ", " in A, B and C at least one " with
And the combination of " A, B, C or any combination of them " includes A, B and/or C any combination, and multiple A can be included,
Multiple B, or multiple C.Specifically, various combinations, such as " in A, B or C at least one ", " at least one in A, B and C
It is individual " and " A, B, C or its any combination ", can be only A, only B, only C, A and B, A and C, B and C, or A and B
And C, wherein any this combination can include one or more member in A, B or C.Any content disclosed herein is all
It is not intended to and offers to the public, no matter whether this disclosure is explicitly recited in claim.
Claims (20)
1. a kind of marker delivery device, including：
Pipe, the pipe has first end and sidewise hole；
At least one biopsy marker, at least one described biopsy marker is set close to the sidewise hole；
Push rod, the push rod, which has, is at least partially disposed on first end in the pipe, wherein the push rod along towards its
The direction of one end is removable with least one described biopsy marker of engagement；And
Elastic component, the elastic component extends from the first end of the push rod, wherein the elastic component is configured to work as
At least one described biopsy marker of engagement is to drive when direction of the push rod along the first end towards the push rod is moved
State the sidewise hole that at least one biopsy marker passes through the pipe.
2. marker delivery device according to claim 1, wherein the pipe includes the projection extended radially inward.
3. marker delivery device according to claim 2, wherein it is described extend internally it is raised close to described lateral
Hole and position.
4. marker delivery device according to claim 2, wherein the projection extended internally includes annular protrusion.
5. marker delivery device according to claim 2, wherein the projection extended internally is recessed including at least two
Fall into.
6. marker delivery device according to claim 2, wherein the projection extended internally includes tongue piece.
7. marker delivery device according to claim 1, in addition to：
Tip, the first end of the tip insertion pipe.
8. marker delivery device according to claim 7, wherein the tip includes ramp portion.
9. marker delivery device according to claim 8, wherein the ramp portion include regulation biopsy marker from
The pre-selection gradient of the angle of the pipe ejection.
10. marker delivery device according to claim 1, wherein the elastic component includes spring.
11. marker delivery device according to claim 10, wherein the spring includes at least one first pitch area
Domain and the second pitch region；The coil in wherein described first pitch region is relative to the second pitch region closely
Accumulation.
12. marker delivery device according to claim 1, wherein the biopsy marker includes absorbable body.
13. marker delivery device according to claim 1, wherein the biopsy marker includes deformable material.
14. a kind of marker delivery device, including：
Pipe, the pipe has first end, wherein the first end includes opening and multiple stop dog components, wherein the multiple backstop
Component is set close to the opening；
At least one biopsy marker, the multiple stop dog component of at least one described biopsy marker close to the pipe is set
Put；And
Push rod, the push rod has the first end being at least partially disposed in the pipe, wherein the push rod is along described in
The direction of the first end of push rod it is removable to drive at least one described biopsy marker by the multiple stop dog component and
Through the opening of the pipe.
15. marker delivery device according to claim 14, in addition to：
Tip, the first end of the tip insertion pipe.
16. marker delivery device according to claim 15, wherein the tip includes ramp portion.
17. marker delivery device according to claim 14, wherein the opening includes sidewise hole.
18. marker delivery device according to claim 14, in addition to：
Elastic component, the elastic component extends from the distal end of the push rod.
19. a kind of marker delivery device, including：
Sleeve pipe, described sleeve pipe has first end and the first opening, and wherein described sleeve pipe includes the first material；
At least one biopsy marker, the biopsy marker is set close to the described first opening；
Set, wherein described be set at least a portion of the first end of sidewise hole and described sleeve pipe, wherein the set includes the
Two openings, wherein second opening of the set is configured to be directed at lateral to be formed with first opening of described sleeve pipe
Hole, wherein the set also includes the second material, wherein second material of the set has the first material than described sleeve pipe
Flexible or elastic small flexible or elasticity；And
Component, the component, which has, is at least partially disposed on first end in described sleeve pipe, wherein the component is along towards institute
The direction for stating the first end of component is removable with by the sidewise hole formed by the described first opening and the described second opening
To dispose at least one described biopsy marker.
20. a kind of marker delivery device, including：
Pipe, the pipe has first end and sidewise hole；
At least one biopsy marker, at least one described biopsy marker is set close to the sidewise hole；
Push rod, the push rod has the first end being at least partially disposed in the pipe, wherein the push rod is along described in
The direction of the first end of push rod is removable with least one described biopsy marker of deployment；And
Actuator, the actuator has plunger, wherein the actuator is connected with the pipe and the push rod, wherein described cause
The plunger of dynamic device can be moved through first position and the second place, wherein the actuator is configured to when the plunger is moved
When moving to the first position, the push rod is moved along the direction of the first end towards the push rod, wherein the actuator structure
Cause when the plunger is moved to the second place, rotate the pipe.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/534,952 US10166084B2 (en) | 2014-11-06 | 2014-11-06 | Spring-ejected biopsy marker |
| US14/534,952 | 2014-11-06 | ||
| US201562134715P | 2015-03-18 | 2015-03-18 | |
| US62/134,715 | 2015-03-18 | ||
| PCT/US2015/059563 WO2016073912A1 (en) | 2014-11-06 | 2015-11-06 | Spring-ejected biopsy marker |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107106254A true CN107106254A (en) | 2017-08-29 |
Family
ID=54542625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580071997.2A Pending CN107106254A (en) | 2014-11-06 | 2015-11-06 | The biopsy marker of spring ejection |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP3215045A1 (en) |
| JP (1) | JP6454794B2 (en) |
| KR (1) | KR20170093137A (en) |
| CN (1) | CN107106254A (en) |
| HK (1) | HK1242947A1 (en) |
| WO (1) | WO2016073912A1 (en) |
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| US11311314B2 (en) | 2018-07-31 | 2022-04-26 | GetSet Surgical SA | Spinal surgery systems and methods |
| PL4278985T3 (en) * | 2019-05-30 | 2025-05-05 | Devicor Medical Products, Inc. | Biopsy site marker for limited migration |
| USD926312S1 (en) | 2019-06-07 | 2021-07-27 | GetSet Surgical SA | Surgical instrument handle |
| USD896384S1 (en) | 2019-06-07 | 2020-09-15 | GetSet Surgical SA | Spinal fusion cage |
| USD926978S1 (en) | 2019-06-07 | 2021-08-03 | GetSet Surgical SA | Surgical instrument handle |
| USD927687S1 (en) | 2019-06-07 | 2021-08-10 | GetSet Surgical SA | Surgical instrument handle |
| WO2021188481A2 (en) * | 2020-03-17 | 2021-09-23 | Devicor Medical Products, Inc. | Biopsy site markers with non-migration features |
| US20250000607A1 (en) * | 2021-11-24 | 2025-01-02 | Bard Peripheral Vascular, Inc. | Vacuum assisted biopsy device with valve-controlled venting and integrated marker delivery |
| WO2024015788A1 (en) * | 2022-07-12 | 2024-01-18 | Merit Medical Systems, Inc. | Mechanism for retaining a marker |
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Also Published As
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| KR20170093137A (en) | 2017-08-14 |
| EP3215045A1 (en) | 2017-09-13 |
| HK1242947A1 (en) | 2018-07-06 |
| JP2017538564A (en) | 2017-12-28 |
| JP6454794B2 (en) | 2019-01-16 |
| WO2016073912A1 (en) | 2016-05-12 |
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