CN106900677A - A kind of controlled-release device and its manufacture method for being sustained volatile materials - Google Patents

Abstract

The present invention relates to a kind of controlled-release device for being sustained volatile materials, including：Main body and hanging portion, the main body includes annular seal space, the capacity of annular seal space is 0.05 15 milliliters, volatile materials is filled with the annular seal space, the wall thickness of the main body be 0.25 1.25 millimeters, the main body, the hanging portion and the alar part by can make the volatile materials from the annular seal space penetrate into air in macromolecule polymeric material be integrally formed.Controlled-release device of the invention can realize more efficient sustained release and discharge complete technique effect compared to prior art, monitored so as to be more suitable as the mating of field interference insect, the release of repellant and can be used for, catched and killed, the lure of attracting and destroying insects.The invention further relates to the manufacture method of the controlled-release device, wherein, including the step of normal temperature filling and sealing.

Description

A controlled release device for slow release of volatile substances and its manufacturing method

technical field

The invention belongs to the technical field of agriculture, and in particular relates to a controlled-release device for slowly releasing volatile substances, which can completely release volatile substances at a uniform speed and basically completely release the volatile substances therein. The invention also relates to a manufacturing method of the controlled release device for slow release of volatile substances.

Background technique

It is well known that low molecular weight volatile chemicals have many existing and potential uses in agriculture, including the use of volatile chemicals as attractants and repellants for pests. The sex pheromone in the insect attractant is a volatile chemical signal sent by the opposite sex to attract each other, while the insect aggregation pheromone is usually produced by insects of a certain sex to play the role of aggregation , Aggregating pheromones can attract both male and female insects of the same kind. In addition, there are other volatile substances in insect attractants such as methyl eugenol, raspberry ketone, gingerone, and these volatile substances are originally produced by plants, but can attract male fruit flies that feed on them, and This pheromone is exchanged for something attractive to female fruit flies.

In addition, there are volatile substances with repelling effect, such as methyl salicylate, which not only repels the pest brown planthopper on rice, but also has the function of attracting its natural enemy, the egg parasitic wasp Oryza spp. .

In addition, it has been documented that certain volatile chemical substances derived from plants or similar to plants, when released into the air, have a good repellent effect on mosquitoes. These volatile substances include, but are not limited to, citronellal, linalool, geraniol.

Therefore, the use of safe volatile substances to control some important pests has become a very effective means, and it has become more and more important to the environment and producers.

In addition, plants can communicate with each other through the release of chemical signals through biologically active volatile compounds, such as methyl jasmonate, which can be released by plants to warn other crops about the activities of insects on the plants. Chemical defense, which secretes certain chemicals that are not conducive to the digestion of insects. Furthermore, these chemical signals between plants may also affect the growth results of certain crops. For example, some plants secrete chemicals that can enhance the vividness of the color of apples.

However, since volatile chemicals are easy to volatilize rapidly in the air, they must be volatilized in a controlled release device to ensure their slow release and long-term effectiveness.

Known in the prior art are solid controlled-release devices, that is, volatile chemical substances are mixed in solid-based controlled-release devices made of wax or polymer materials, such as lures made of wax blocks or rubber heads. Core, this type of product is very simple to make, but the release rate cannot be guaranteed, and its release rate has a lot to do with the volatilization speed and concentration of the volatile chemical substances in the controlled release device. When the concentration of active substances decreases, the volatilization rate will also decrease, which will affect the effect. Although this controlled release device is simple, it causes a great waste of volatile chemicals. Because the volatile species are released too quickly and too much initially, soon there is too little volatile chemical species remaining due to lower concentrations. This situation results in a poorly achieved effect. Especially when a large amount of expensive insect sex pheromones are used to achieve the purpose of prevention and control by interfering with mating technology, such volatile compounds are expensive, and the waste in the early stage leads to very high costs.

In addition, the rubber head lure containing sex pheromone is used as a controlled release device for the purpose of attracting. When the lure releases too high a concentration of sex pheromone, it may play a role in avoiding rather than attracting the target insects; When it is low, the ability to attract target insects cannot be sufficient. Therefore, neither of these two cases is suitable for practical application for the purpose of booby-trapping. Such controlled-release devices also cannot precisely control the volatilization concentration and speed of volatile substances.

In addition to the aforementioned solid-type controlled-release devices, storage-type controlled-release devices are known in the prior art. Generally speaking, control devices that can release the contained volatile substances to close to zero are collectively referred to as storage-type controlled-release devices. Several of the different types of depot-based controlled release devices are commercially available.

US Patent No. 4,600,146 discloses an extruded tubular controlled release device. Among them, an extrusion-type capillary releaser is disclosed. The extruder injects pheromone while extruding the capillary, and then cuts off the seal. The lumen of the capillary is narrow (usually 1 to 3 mm in diameter). If you want to squeeze out the capillary and then fill the capillary with pheromone at room temperature, the frictional resistance will be very high, so that if you want to squeeze out the capillary again Complete filling of these capillaries is not possible in production. In actual industrial production, the extrusion of the capillary and the injection of the pheromone are carried out at the same time, and then cutting and sealing are performed. Filling the pheromone while extruding the capillary means that the pheromone is exposed to the high temperature of the molten plastic, and The production process of achieving precise filling while extruding is expensive and cumbersome. In addition, there are many host plant volatile compounds or similar compounds that cannot be used to fill such capillaries because many of them have boiling points close to or below the melting point of plastics. At the same time, the volume of the lumen of this capillary releaser is limited. Host plant volatile compounds are usually used in greater amounts than insect pheromones, making such compounds unsuitable for hot-filling capillaries.

US Patent No. 4,923,119 discloses a bag-packed controlled-release device, which uses a simple bag-pack releaser capable of releasing pheromones. The advantage of such a release is that it is cheap to manufacture. Actually they are suitable for full filling. The disadvantage of this release is that the walls are very thin, typically about 0.01 mm thick. Although this type of bag dispenser performs well in a room temperature-controlled laboratory environment, this type of pheromone-containing bag dispenser is prone to a large and rapid release of pheromone in a high temperature environment, resulting in waste , affecting its efficiency.

US Patent No. 5,316,148 discloses a controlled release device for capsules, which specifically discloses a vacuum capsule releaser. One side of the releaser is impermeable, and the other side is made of a thin membrane that releases the pheromone. Films used on such dispensers inevitably suffer from the same problems as the bag-like controlled release devices described above.

Furthermore, in German patent DE3640880 a controlled-release device is disclosed which is likewise blow-molded, heat-filled and hermetically connected. The controlled-release device is composed of one or two thin-walled capsules on the upper part and a reserved cavity containing pheromone in the lower part. The thickness of the upper part is 0.02-0.15 mm, and the pheromone is released through the upper film. However, due to the thickness of the lower part, the lower part cannot release pheromone normally according to the predetermined rate, resulting in a large amount of pheromone remaining in the reserved cavity at the lower part, resulting in waste. In addition, such releases are relatively expensive to manufacture.

In addition, as mentioned above, lure cores also use pheromones to monitor and forecast target insects, and this technology has a history of many years. The purpose of monitoring is mainly to collect the occurrence, algebra and population activity of a certain insect in the field. Through monitoring data, farmers can keep abreast of the occurrence of target pests and take timely control measures when necessary. Under normal circumstances, the number of monitoring lures used is very small, for example: use 1 per 10-20 mu. In this case, the lures only play a role in attracting during monitoring and will not affect the target pests. Population numbers and occurrences.

However, in practical applications, many pests can be prevented and controlled by trapping and killing a large number of aggregated pheromones. However, the pheromone releaser used in trapping has a slow-release and long-lasting function, which is very necessary for commercial field applications, otherwise the large amount of labor costs caused by frequent replacement of lure cores will make this trapping method Because the cost is too high, farmers can't afford it and can only stay in the stage of monitoring and reporting.

Some important moths can also be controlled by trapping and killing. Such as corn borer (Ostrinia furnacalis) and rice stem borer (Chilo suppressalis), compared with the large insects mentioned above, these moths only need very little pheromone to play the role of attracting, and each lure only needs Less than 0.2mg of pheromones, which tend to be sex pheromones. These sex pheromones have a volatilization effect, and they will attract similar males when they volatilize in the air. For the sustained and long-term release of these sex pheromones, it is necessary to place the sex pheromones in a releaser with a slow-release effect to play a role.

Generally speaking, the pheromones of small moths are carried by lures made of small rubber heads. Although this method has been used for many years, it still has great limitations. First of all, the volatilization rate of the lure made with a small rubber head carrying pheromone is unstable. Also at 25°C, after half of the pheromone is released, the daily release of pheromone in the lure will be reduced to half of the original , which means that the release amount at the beginning is too high, but the release amount later is not enough, resulting in waste. Secondly, in addition to the unstable release amount, the effective duration of the rubber head lure is very short, generally no more than one month, so it needs to be replaced at least once a month. It needs to be replaced at least 6-7 times, which will not only increase the cost, but also the labor cost will be very expensive, and it is completely unsuitable for commercial use and promotion. The limitation of the rubber head lure is also reflected in the very limited amount of pheromone that a rubber head can carry. When it is necessary to mix a large number of other volatile compounds to enhance the attraction of the main compound, the pheromone that the rubber head can carry The amount is limited because it cannot be effectively increased.

Therefore, there is an urgent need in the prior art for a controlled-release device that can solve the aforementioned problems, not only realize the release of volatile substances at a completely uniform speed, but also achieve the ultimate goal of making it completely volatilize without leaving residues, and the controlled-release device is also It can be used as a lure to ensure long-term release of volatile substances, which is more suitable for monitoring, trapping and killing insects.

Contents of the invention

The present invention is proposed based on the foregoing problems.

In order to solve the aforementioned problems, the present invention provides a controlled-release device for slow-release volatile substances, including: a main body and a hanging part, the main body includes a sealed cavity, and the capacity of the sealed cavity is 0.05-15 ml. Volatile substances are filled in the sealed cavity, the wall thickness of the main body is 0.25-1.25 mm, and the main body is made of high molecular polymer material capable of allowing the volatile substances to penetrate into the air from the sealed cavity.

According to another aspect of the present invention, the volatile substances are insect pheromones, quasi-pheromones, volatile compounds of host plants or mixtures thereof.

According to yet another aspect of the present invention, the volatile substance is an insect repellant.

According to another aspect of the present invention, the volatile substances are botanical volatile substances that affect plants.

According to yet another aspect of the present invention, the outer surface of the body may be coated with one or more insecticides.

According to another aspect of the present invention, the body has a wall thickness of 0.5-1.0 mm.

According to yet another aspect of the present invention, the capacity of the sealed chamber is 0.1-3.0 milliliters, and the volatile substances include volatile solvents and volatile pheromones; the ratio of the volatile solvents to the volatile pheromones is 9:1 to 10000:1.

According to another aspect of the present invention, the controlled release device further comprises wings.

According to still another aspect of the present invention, the thickness of the wing portion is lower than the thickness of the main body and the hanging portion.

According to another aspect of the present invention, the cross-section of the body becomes gradually larger in a vertical direction.

According to yet another aspect of the present invention, the present invention also provides a method for manufacturing a controlled-release device for slow-release volatile substances, comprising the following steps: (a) preparing materials and mixing them at a melting temperature of 180-280° C. dissolving the high molecular polymer material, and adding an antioxidant at the same time; (b) injection molding, performing injection molding on the melted material in step (a) under the condition that the mold temperature range is 20-70°C and the injection pressure range is 70-105MPa, and completely cooled; (c) filling and sealing at room temperature, filling and sealing the formed controlled-release device at room temperature.

According to another aspect of the present invention, said controlled release devices may be manufactured connected together in rows.

According to the controlled-release device for slow-release volatile substances of the present invention, through the design of the volume and wall thickness of the main body, the volatile substances in the main body can penetrate into the polymer material to achieve long-term slow-release and finally complete release technology Effect. In addition, it can be used as a long-term lure by mixing the ratio of volatile solvent and volatile pheromone. Therefore, it can not only interfere with the mating of pests, attract or repel pests, affect the transmission of signals between plants, etc., but also have beneficial effects of monitoring, trapping, and trapping pests.

According to the manufacturing method of the present invention, the production process of the main body or the lumen can be completely separated from the liquid filling, and the cavity can be filled at normal temperature, thereby overcoming the need for high temperature production and filling in the prior art. Due to the defects of simultaneous filling, many plant volatile compounds with boiling points close to or lower than the melting point of plastics can be widely used by filling them into controlled release devices at room temperature. Also, since the main body or the lumen can be injection-molded, the liquid can be filled and sealed when needed, thus avoiding waste in production and making the manufacture and application of the controlled-release device more flexible

Description of drawings

Fig. 1 is a three-dimensional schematic diagram of a controlled release device for slow release of volatile substances before filling and sealing according to the present invention;

Fig. 2 is a schematic front view of a controlled release device for slow release of volatile substances in Fig. 1;

Fig. 3 is a schematic right side view of a controlled release device for slow release of volatile substances in Fig. 1;

Fig. 4 is a schematic top view of a controlled release device for slow release of volatile substances in Fig. 1;

Fig. 5 is a schematic bottom view of a controlled release device for slow release of volatile substances in Fig. 1;

Fig. 6 is a schematic cross-sectional view along the A-A direction in Fig. 5;

Fig. 7 is a schematic cross-sectional view along the B-B direction in Fig. 5;

Fig. 8 is an example of a specific application effect of a controlled release device for slow release of volatile substances according to the present invention;

Fig. 9 is another specific application effect example of a controlled release device for slow release of volatile substances according to the present invention;

Fig. 10 is another example of specific application effects of a controlled-release device for slow-release of volatile substances according to the present invention.

Fig. 11 is a practical application picture of a controlled release device for slow release of volatile substances according to the present invention.

Reference signs: 1. Main body; 2. Hanging part 3. Wing part

detailed description

The present invention will be further described in detail below in conjunction with the accompanying drawings. It should be noted that, in the case of no conflict, the embodiments in the present application and the features in the embodiments can be combined with each other.

As mentioned above, Fig. 1 is a three-dimensional schematic diagram of a controlled release device for slow release of volatile substances according to the present invention before filling and sealing; Fig. 2 is a controlled release device for slow release of volatile substances in Fig. 1 Figure 3 is a schematic diagram of a right side view of a controlled release device for slow release of volatile substances in Figure 1; Figure 4 is a schematic top view of a controlled release device for slow release of volatile substances in Figure 1; Figure 5 It is a schematic bottom view of a controlled-release device for slow-release of volatile substances in FIG. 1; FIG. 6 is a schematic cross-sectional view along the A-A direction in FIG. 5; FIG. 7 is a schematic cross-sectional view along the B-B direction in FIG.

As shown in FIG. 1 , a controlled release device for sustained release of volatile substances according to the present invention includes a main body 1 including a sealed cavity. In terms of appearance, the main body 1 is roughly cylindrical. It should be readily understood that the sealed chamber is used for filling volatile substances and is sealed after filling. In other words, the cylindrical body is filled with volatile substances, such as pheromones, repellants, etc., but not limited thereto. Or it can be said that the volatile substance filled in the cylindrical body depends on the specific application of the controlled release device. The size of the inner chamber volume of the simplified body of the main body 1 can be determined according to the purpose of use of the controlled release device. As an embodiment, the filling volume of the inner chamber is in the range of 0.05 milliliters (ml) to 15 milliliters (ml) , for example, can be 0.05 ml, 1 ml, 1.5 ml, 2 ml, 2.5 ml, 3 ml, 3.5 ml, 4 ml, etc. The cross section of the simple shape can be any one of circle, ellipse, rhombus, square, hexagon etc., but not limited thereto. As an embodiment, preferably, the cross-sectional diameter of the cylindrical body gradually increases from top to bottom, that is, the main body 1 appears to gradually widen from the outside, which not only facilitates production by injection molding, but also Especially filling and sealing, and can make the controlled-release device maintain better stability during application. As another embodiment, the cross-sectional diameter of the cylindrical body is uniform from top to bottom. Of course, it is also conceivable that the diameter of the cross-section of the cylindrical body gradually decreases from top to bottom, which is still applicable, but it is not conducive to manufacturing by injection molding process.

The wall thickness of the main body 1 is preferably between 0.25 millimeters (mm) and 1.25 millimeters (mm), more preferably, the wall thickness of the main body 1 is between 0.5 millimeters and 1 millimeter. As an example, the wall thickness range of the main body 1 may be 0.3 mm, 0.4 mm, 0.5 mm, 0.6 mm, 0.7 mm, 0.8 mm, 0.9 mm and so on. Experiments have proved that the wall thickness within the above numerical range can buffer the excessive release of volatile substances such as pheromones filled in the cylinder under high temperature conditions, and reduce the volatile substances such as pheromones caused by high temperature during the day. The volatilization of volatile substances of the class. In addition, a controlled-release device with a main body wall thickness exceeding 1.25 mm usually causes waste of polymer materials, and at the same time, it is inconvenient to seal the main body 1 during filling.

There is a hanging part 2 at the opposite end of the main body 1 to the substantially cylindrical body that is filled with volatile substances and sealed after filling. As an embodiment, the hanging part 2 can be molded with the main body 1 at one time, which can reduce the production cost. In addition, as another embodiment, the hanging part 2 can also be formed separately from the main body 1 , for example, the main body 1 and the hanging part 2 are connected together by welding. As an embodiment, preferably, the hanging part 2 includes two parts with a middle cutout, as shown in FIG. 1 . The purpose of the break in the middle is to facilitate the hanging of the entire controlled release device during application and the unloading after use. Of course, the hanging portion can be in other shapes that are beneficial for clamping and hanging, such as a buckle, a strap, and the like. The hanging part is used to hang the controlled release device at the position where it is needed. As an example, for example, hanging on crop branches, but not limited thereto. Therefore, the hanging portion must have a sufficient thickness m in the front-rear direction, so that the controlled-release device with filling liquid can be hung firmly at the desired position and remain effective in time. Preferably, the thickness m of the hanging part is between 3mm-4mm. Practice has proved that within this thickness range, even if the hanging part is made of a polymer material with a lower hard bottom, such as low-density polyethylene (LDPE), soft plastic and other materials, the controlled release device can be kept firmly. Hang it where you need it.

As shown in FIGS. 1 , 2 and 6 , the controlled release device according to the invention further comprises wings 3 . Preferably, the wings 3 are arranged symmetrically on both sides of the main body 1 . Similar to the hanging part 2, as an embodiment, the wing part 3 can be integrally formed with the main body 1, which can reduce the production cost. In addition, as another embodiment, the wing part 3 can also be formed separately from the main body 1, for example, the main body 1 and the wing part 3 are connected together by welding. Preferably, in one embodiment, the main body 1, the hanging part 2 and the wing part 3 are integrally formed, which greatly reduces the production cost. The advantage of the symmetrical arrangement of the wings 3 is not only that it can maintain the stability of the controlled-release device when it is hung, but also that the wings 3 have the function of connecting a single controlled-release device. It is more convenient for the production of the controlled release device. For example, several controlled-release devices connected together can be molded at one time, for example, 5 or 10, and each controlled-release device is connected by wings, but it is not limited to this, and several controlled-release devices connected together are also included. Release device for filling, sealing, packaging, application, etc. In this case, the wing 3 can be used as a connecting part where several individual devices are connected together. Therefore, as an embodiment, preferably, the material thickness of the wing part 3 is generally thinner than other parts, such as the main body 1 and the hanging part 2, so as to facilitate separation when necessary. As another embodiment, when forming several single controlled release devices connected together at one time, in addition to connecting through the wing part 3, it can also be connected through the hanging part 2, that is, two adjacent controlled release devices The hanging parts of the units are also connected together, thereby enhancing connection reliability between individual devices. At this time, the hanging part 2 also has a joint for connection, which is preferably the same as the wing part, that is, a material that is thinner than other parts such as the main body 1, and the purpose is also to facilitate several joints together. Separation of the controlled release device.

The following introduces the application of a controlled release device for slow release of volatile substances according to the present invention. As previously stated, the controlled release device shown in the figures is a schematic view prior to being filled and sealed. When practically applied, the controlled-release device is a device that has been filled with corresponding volatile substances and sealed well. A practical application of the controlled release device is shown in FIG. 11 .

As an example, the mating interference technology is generally used to control target pests in the field, and a large amount of insect sex pheromones are required at this time. For example, control of codling moth (Cydia pomonella) infestation typically uses mating disruption techniques. The desired number of controlled-release devices can be hung per acre in the field, e.g., in the case of codling moth pheromones for mating disruption techniques, with e.g. 100 mg of codling moth sex information per release Taking prime as an example, at this time, 66 are usually applied per mu. Of course, if you want to save the labor cost required for use, you can increase the amount of liquid in each controlled release device, for example, when each release device contains 200 mg of codling moth sex pheromone, only 33 .

In addition, for example, a controlled release device for slow release of volatile substances according to the present invention can be filled with plant volatile compounds as repellants against insects. For example, dimethyl disulfide, volatilized from damaged guava leaves, can be used to repel psyllids (Psyllid Diaphorina citri). The psyllid is the main cause of citrus yellowing or Huanglongbing. For example, Z,3Hexenyl acetate can also be filled, which can attract certain parasitic insects and natural enemies. For example, methyl jasmonate (methyl jasmonate) can also be filled, which can be used as a signal molecule to influence or warn other plants, activate other plants' immune mechanisms against herbivores, such as protease inhibitors, thereby affecting herbivores' response to proteins Absorption of nutrients.

The high molecular polymer material used in the controlled release device must allow one or more volatile substances to penetrate into the air from the controlled release device, such as polyethylene and soft polyvinyl chloride, but not limited thereto. As mentioned above, the capacity of the main body 1 to hold liquid is between 0.05 and 15 milliliters; the thickness of the main body 1 is between 0.25 and 1.25 mm. In addition, the process of filling or filling the main body 1 of the controlled release device can be completed at normal temperature. The filling seal of the main body 1 of the controlled release device is sealed by heating or ultrasonic welding.

In addition, the volatile substances filled in the controlled-release device can be one or more insect pheromones, quasi-pheromones, volatile compounds of host plants or the above-mentioned mixed compounds that can affect the behavior of insects. The volatile substance filled in the controlled-release device can be an insect repellant, and also one or more plant volatile substances that affect plants. As examples, for example, (Z)-11-tetradecen-1-yl tortrix pheromone acetate, (Z)-9-tridecene housefly pheromone, α-pinene, etc., but not limited thereto.

As an embodiment, the outer surface of the controlled release device made of high molecular polymer material can be coated with one or more insecticides, or one or more insecticides can be incorporated into the polymer material .

The controlled-release device for slow-release volatile substances according to the present invention can be used to attract or avoid pests, or control pests, and it can also affect the absorption of protein substances by herbivores by releasing volatile substances that affect plant physiological characteristics. As an example, methyl jasmonate, as mentioned above, can be used as a signal molecule to influence or warn other plants, activate other plants’ immune mechanisms against herbivores, such as protease inhibitors, thereby affecting herbivores’ response to Absorption of protein nutrients.

As another embodiment, the volatile substances in the main body 1 include a volatile solvent and a volatile pheromone, and the volatile solvent is used to dissolve the volatile pheromone. The capacity of the sealed chamber is 0.1-3.0 ml, and the ratio of the volatile solvent to the volatile pheromone is 9:1 to 10000:1, preferably, such as 99:1, such as 999:1. The reason for the large ratio between the selected volatile solvent and the pheromone to be dissolved is that the volatilization rate of the dissolved pheromone can then be determined by the volatilization rate of the solvent. In addition, stabilizers such as antioxidants may be added to the volatile substances. It should be noted that the volatile solvent has no repelling effect on the target insects, but it can have a synergistic effect on the dissolved pheromone, and must have a good dissolution effect on the pheromone. The volatile solvent can volatilize and penetrate the releaser tube wall However, it will not dissolve the releaser and will not form liquid on the outer surface of the releaser tube wall. In this embodiment, the controlled release device can be used as a long-term lure for monitoring and can also be used as a long-term trapping tool in the trapping technology. It also has the technical effect of long-acting sustained release and can finally release completely.

Suitable solvents include, by way of example, isopropanol, which is a very neutral solvent and has no effect on insects. Other solvents can also be plant volatiles that have a synergistic effect on pheromones, such as methyl salicylate, linalool, α-farnesene, and hexyl acetate.

For example, release 0.5mg of codling moth sex pheromone every day with a releaser containing codling moth sex pheromone, release continuously for 200 days, release 10mg of isopropyl alcohol for dissolving codling moth sex pheromone in the releaser every day, Also continuously release 200 days as the goal, thus the required codling moth sex pheromone amount is 0.5x200=100mg, and the required isopropanol amount is 10x200=2000mg; the density of isopropanol is 0.786g/ml, Therefore, it is calculated that the minimum volume of liquid filling in the lumen of this releaser is 2.8ml. The weight ratio between isopropanol and codling moth sex pheromone is 20:1. Therefore, according to this ratio, the releaser can realize the long-acting sustained release function of 200 days.

An example of the use of the main body 1 filled with leaf tortrix pheromone made of polyethylene and soft polyvinyl chloride is introduced below.

In an application of the controlled-release device of the present invention, the controlled-release device made of soft polyvinyl chloride with a wall thickness of the main body 1 of 1.25mm is filled with (Z)-acetic acid 11-tetradecen-1- The main ingredient in the pheromone of yl leaf roller moth (Adoxophyes orana), the filling volume is 0.05ml. At room temperature, measure the release rate of the controlled-release device and record the data to an accuracy of 0.1 mg, and the entire test lasts for 121 days. During this period, the normal temperature value is between 20-30 degrees Celsius. This temperature range is also a suitable temperature for most crops during the growth period, and the test results are shown in Figure 8. The relationship between the daily release amount and the number of exposure days is shown in FIG. 8 . It can be seen from Fig. 8 that the controlled-release device filled in this way can achieve the function of long-acting sustained release.

In another application of the controlled release device of the present invention, the controlled release device whose main body 1 is made of soft polyvinyl chloride is filled with the macromolecular compound housefly pheromone. Specifically, in a controlled-release device with a wall thickness of 0.25 mm in the main body 1 made of soft polyvinyl chloride, (Z)-9-tridecene housefly pheromone is filled, and the filling volume is 0.5 ml . At room temperature, the release rate of 15 controlled-release devices was measured and the data was recorded to an accuracy of 0.1 mg. The entire test lasted for 70 days. During this period, the normal temperature value is between 20-30 degrees Celsius. The test results are shown in Figure 9. The relationship between the daily release amount and the number of exposure days is shown in FIG. 9 . This Figure 9 shows that at the very beginning, the release rate is very low because the pore walls are not yet completely penetrated by the contained chemical species, until all the pore walls have started to be permeated, the release rate remains steady state. And achieve the function of long-acting sustained release.

Another example is the application situation of filling the small molecular compound α-pinene with the controlled release device whose main body 1 is made of polyethylene as follows. In a controlled-release device with a main body 1 made of polyethylene and a wall thickness of 0.9 mm, the small molecular compound α-pinene was filled with a filling volume of 15 ml. At room temperature, measure the release rate of 15 controlled-release devices and record the data to an accuracy of 0.1 mg. The entire test lasts for 100 days. During this period, the normal temperature value is between 20-30 degrees Celsius. The test results are shown in Figure 10. Figure 10 shows the relationship between the amount released per day and the number of days of exposure. It can be seen from Figure 10 that when the filling volume reaches 15ml, α-pinene can still achieve long-term sustained release. Therefore, the long-acting controlled-release device can also be used in the monitoring, trapping and trapping of various pests, which can save manpower and material resources.

The following introduces several cases of filling applications of solvents and pheromones together.

Example 1: Hexyl acetate is used as a solvent to mix and fill with the sex pheromone of the Asian corn borer. Hexyl acetate is a fast volatile solvent, and its ratio to the sex pheromone of Ostrinia officinalis is 99:1. The main body 1 of the controlled release device is made of polyethylene material. Specifically, 25 controlled-release devices with a wall thickness of 0.8 mm and polyethylene as the main material were used in the test, and each release device was filled with 1.0 ml of a mixed liquid containing 99% of the solvent hexyl acetate and 1 % sex pheromones of Ostrinia sativa. At room temperature, the release rate of 25 controlled-release devices was measured and the data was recorded to an accuracy of 0.1 mg. The entire test lasted for 190 days. During this period, the normal temperature value is between 20-30 degrees Celsius. In the course of the test, five times were divided, and two controlled-release devices were randomly selected each time to measure the weight of the remaining mixed solution and the content percentage of the sex pheromone in the mixed solution. The results are shown in Table 1 below.

Table 1: Filling mixed with hexyl acetate as solvent and sex pheromone

It can be seen from the test results that during the whole test process, the percentage content of the Asian corn borer pheromone in the mixed solution basically did not change, but the weight of the mixed solution was slowly decreasing, which means that the mixed solution was slowly released, It is proved that when the proportion of volatile solvent in the mixture is absolutely dominant, the sustained release rate of the volatile solvent determines the release rate of the mixture and other volatile components in the mixture.

This test also proves that, as a long-acting controlled-release device with slow-release function, it can carry a variety of insect pheromones through volatile solvents, which can be applied to the monitoring, trapping, and killing of various pests, and it also saves manpower and material resources.

Example 2: Mixed filling with methyl salicylate as solvent and sex pheromone of Asian corn borer

Use 25 controlled-release devices with a wall thickness of 0.8 mm polyethylene material as the main body to fill the liquid mixed with methyl salicylate as a solvent and the sex pheromone of the Asian corn borer, and the methyl salicylate can volatilize quickly. The mixed liquid contains 99% of the solvent methyl salicylate and 1% of the sex pheromone of the Asian corn borer, that is, they are mixed in a ratio of 99:1, and each controlled release device is filled with 1.0ml of the mixed liquid. At room temperature, the release rate of 25 controlled-release devices was measured and the data was recorded to an accuracy of 0.1 mg. The entire test lasted for 190 days. During this period, the normal temperature value is between 20-30 degrees Celsius. In the course of the test, two controlled-release devices were randomly selected for five times each time to measure the weight of the remaining mixed solution and the content percentage of the sex pheromone in the mixed solution. The test results are shown in Table 2 below:

Table 2: Methyl salicylate as a solvent mixed with the sex pheromone of Ostrinia officinalis

From the test results, it can be seen that the percentage of sex pheromone in the mixed solution basically did not change during the whole test, but the weight of the mixed solution was slowly decreasing, which means that the mixed solution was slowly released , which proves that when the proportion of volatile solvent in the mixed solution is absolutely dominant, the sustained release rate of the volatile solvent determines the release rate of the mixed solution. This example shows that the controlled-release device according to the present invention can be used as a long-acting slow-release application, which can monitor, trap and trap various pests, and can save manpower and material resources.

Example 3: Filling mixed with codling moth sex pheromone using α-farnesene as solvent

Using α-farnesene as a solvent, 1% codling moth sex pheromone was added at a ratio of 99:1, and the mixed liquid was filled in the controlled release device of the main body 1 made of polyethylene material. In this test, 25 controlled-release devices with a wall thickness of 0.8 mm were used. The mixed liquid contained 99% of the solvent α-farnesene and 1% of codling moth sex pheromone, and each controlled-release device was filled with 1.0 ml mixed liquid. At room temperature, the release rate of 25 controlled-release devices was measured and the data was recorded to an accuracy of 0.1 mg. The entire test lasted for 190 days. During this period, the normal temperature value is between 20-30 degrees Celsius. During the test, five times were divided, and two controlled-release devices were randomly selected each time to measure the weight of the remaining mixed solution and the content percentage of codling moth sex pheromone in the mixed solution. The test results are shown in Table 3 below:

Table 3: α-farnesene as a solvent mixed with codling moth sex pheromone filling

From the test results, it can be seen that the percentage of codling moth sex pheromone in the mixed solution basically did not change during the whole test, but the weight of the mixed solution was slowly decreasing, which means that the mixed solution was slowly released , which proves that when the proportion of volatile solvent in the mixed solution is absolutely dominant, the sustained release rate of the volatile solvent determines the release rate of the mixed solution. This example shows that the controlled-release device of the present invention can be used as a long-acting slow-release application, which can monitor, trap and kill various pests, saving manpower and material resources.

Example 4: Filling with α-farnesene as a solvent and sweet potato beetle sex pheromone

α-Farnesene is used as a solvent, 0.01% of the sweet potato beetle sex pheromone is added according to the ratio of 9999:1, and the mixed solution is filled in a controlled release device whose main body is made of polyethylene material. 25 controlled-release devices with a wall thickness of 0.5mm are used to fill the mixed liquid, that is, the mixed liquid contains 99.99% of the solvent d-farnesene and 0.01% of the sex pheromone of the sweet potato weevil, each controlled-release Fill the device with 1.0ml of mixed liquid. At room temperature, the release rate of 25 controlled-release devices was measured and the data was recorded to an accuracy of 0.1 mg. The entire test lasted for 112 days. During this period, the normal temperature value is between 20-30 degrees Celsius. During the test, it was divided into 3 times, and two controlled release devices were randomly selected each time to measure the weight of the remaining mixed solution and the content percentage of the sex pheromone in the mixed solution. The test results are shown in Table 4 below:

Table 4: Mixed filling with α-farnesene as solvent and sex pheromone of sweet potato weevil

It can be seen from the test results that during the whole test process, the percentage content of the sex pheromone in the mixed solution has not changed substantially, but the weight of the mixed solution is slowly decreasing, which means that the mixed solution has slowly The release proves that when the proportion of volatile solvent in the mixed solution is absolutely dominant, the sustained release rate of the volatile solvent determines the release rate of the mixed solution. This example can show that the controlled-release device according to the present invention can be used as a long-acting slow-release application, which can monitor, trap, trap and kill various pests, and can save manpower and material resources.

Example 5: Linalool is used as a solvent to mix and fill with Xingtianniu sex pheromone

Using linalool as a solvent, add 10% of the sex pheromone in the ratio of 9:1, and fill the mixed liquid in the controlled release device of the main body 1 made of soft polyvinyl chloride material. 25 controlled-release devices with a wall thickness of 0.5mm are used to fill the mixed liquid, which contains 90% solvent linalool and 10% celestial bovine sex pheromone, and each releaser is filled with 1.0ml mixed liquid liquid. At room temperature, the release rate of 25 releasers was measured and the data was recorded to an accuracy of 0.1 mg. The entire test lasted for 112 days. During this period, the normal temperature value is between 20-30 degrees Celsius. During the test, it was divided into 3 times, and two controlled release devices were randomly selected each time to measure the weight of the remaining mixed solution and the content percentage of the sex pheromone in the mixed solution.

The test results are shown in Table 5 below:

Table 5: Linalool as a solvent mixed with Xingtianniu sex pheromone filling

It can be seen from the test results that during the whole test process, the percentage content of the sex pheromone in the mixed solution basically did not change, but the weight of the mixed solution was slowly decreasing, which means that the mixed solution was slowly released, It is proved that when the proportion of volatile solvent in the mixture is absolutely dominant, the sustained release rate of the volatile solvent determines the release rate of the mixture. This example can show that the controlled-release device according to the present invention can be used as a long-acting slow-release application, which can monitor, trap, trap and kill various pests, and can save manpower and material resources.

In addition, as mentioned above, the controlled-release device according to the present invention can be molded, filled, transported and used in several connected ways, which has the advantages of: firstly, the number of molds can be reduced, and equipment costs can be saved; secondly, It can improve production efficiency and save production costs in terms of filling and sealing; third, it can be packaged and transported as a whole, reducing logistics costs; fourth, it can be hung more stably during application and prolongs its service life.

The manufacturing method of the controlled-release device according to the present invention is described below.

As for the manufacturing method of the controlled-release device for slow-release volatile substances commonly used in the prior art, the filling of the liquid in the cavity is completed at the same time as the controlled-release device is produced at high temperature.

As mentioned above, U.S. Patent No. 4,923,119 discloses a method of manufacturing a controlled release device, which mainly utilizes extrusion to produce a release device, injects pheromone while extruding, and then cuts off the seal, but, Due to the narrow lumen of the releaser, it is difficult to fill the lumen with liquid at room temperature after extrusion. Pour it in. Therefore, in the prior art, the liquid is filled and the lumen is sealed while extruding the releaser at high temperature. However, this simultaneous filling of the dispenser at high temperatures exposes the liquid to be filled, such as pheromones, to the high temperatures of the molten plastic, and many of these liquids, such as plant volatile compounds, The boiling point is close to or even lower than the boiling point of plastics, so the operation of completing high-temperature filling requires very precise operation, resulting in high production costs and complicated operations. There are even some plant volatile compounds that cannot be bottled in this way of production because their boiling points are too low. It is well known that plant volatile compounds are used in a wide range of applications and in large quantities, whereby this production method is rather limited.

After long-term research and practice, the inventor of the present application has created a solution that completely separates the production of the controlled release device from the filling, so that the filling can be carried out at room temperature, thereby simplifying the production process and improving the safety and reliability of production , increasing the scope of application, thereby enabling many low-boiling volatiles to be applied).

Preferably, the releaser is produced by using an injection molding process, which can optimize the production process and achieve the purpose of one-time molding of the main body and the hanging part, which is more economical. As mentioned earlier, high-molecular polymer materials, such as polyethylene or soft polyvinyl chloride, are selected as raw materials because they have micropores on the surface after molding, and these micropores allow the odor of the liquid in the cavity to penetrate into the air.

The specific steps include: (a) preparing materials, mixing and dissolving high molecular polymer materials at a melting temperature of 200-250 ° C, such as polyethylene or soft polyvinyl chloride materials, but not limited to this, and adding antioxidants at the same time. The additive amount is about 2% (b) Injection molding, set the temperature of the mold in the range of 20-70°C and the injection pressure in the range of 70-105MPa, and inject the dissolved polymer material, and then Cool the injection molded product completely; (c) fill and seal at room temperature, put the formed controlled release device into the slot of the filling machine at room temperature, fill it with a conventional multi-head filling liquid pump, and pass Sealing by ultrasonic welding. The normal temperature here refers to the temperature range suitable for normal production of workers. As an example, the range of 5-40°C is acceptable, for example, it can be 10°C, 15°C, 20°C, 25°C, 30°C, 35°C, but not limited to this. It is also possible to select a mold with multiple releasers, so that multiple releasers connected together can be produced at one time during production, thereby improving production efficiency.

According to the above-mentioned method for manufacturing a controlled-release device of the present invention, since the production process of the main body or cavity of the controlled-release device can be completely separated from the process of filling liquid, and liquid filling and sealing can be performed at normal temperature, it is more suitable It is used in the application of many plant volatile compounds whose boiling point is close to or lower than the melting point of plastics. Therefore, the application of the controlled-release device manufactured by this method is more extensive. In addition, since the main body or lumen can be injection-molded and then filled and sealed with liquid when needed, production waste is avoided, and the manufacture and application of the controlled-release device are more flexible.

Although the device of the present invention has been described in detail with reference to exemplary embodiments, it should be understood that the present invention is not limited to the specific embodiments described in detail and shown in the drawings, without departing from the scope defined in the claims. Under certain circumstances, those skilled in the art may make various modifications to the exemplary embodiment, and the modifications shall fall within the protection scope of the present invention.

Claims (10)

1. A controlled-release device for slow-release volatile substances, comprising: a main body (1) and a hanging part (2), characterized in that the main body (1) includes a sealed cavity, and the capacity of the sealed cavity is 0.05 -15 milliliters, the sealed cavity is filled with volatile substances, the wall thickness of the main body (1) is 0.25-1.25 mm, and the main body (1) is made of a material that can make the volatile substances flow from the sealed cavity Made of high molecular polymer material that is permeable to air. 2. The controlled-release device according to claim 1, wherein the volatile substance is an insect pheromone, a quasi-pheromone, a host plant volatile compound or a mixture thereof. 3. The controlled-release device according to claim 1, wherein the volatile substance is an insect repellant. 4. The controlled-release device according to claim 1, characterized in that, the volatile substances are botanical volatile substances that affect plants. 5. The controlled release device according to claim 1, characterized in that, the outer surface of the main body (1) can be coated with one or more insecticides. 6. The controlled release device according to claim 1, characterized in that, the wall thickness of the main body (1) is 0.5-1.0 mm. 7. The controlled-release device according to claim 1, wherein the capacity of the sealed cavity is 0.1-3.0 milliliters, and the volatile substance comprises a volatile solvent and a volatile pheromone; the volatile solvent and The ratio of the volatile pheromone is 9:1 to 10000:1. 8. The controlled release device according to any one of the preceding claims 1-7, characterized in that it further comprises wings (3). 9. A method for manufacturing a controlled release device according to any one of the preceding claims 1-8, comprising the steps of: (a) preparing materials, mixing and dissolving polymer materials at a melting temperature of 180-280° C., and adding antioxidants; (b) injection molding, injection molding the material dissolved in step (a) under the condition that the mold temperature range is 20-70° C. and the injection pressure range is 70-105 MPa, and completely cool; (c) Filling and sealing at room temperature, filling and sealing the formed controlled-release device at room temperature. 10. The method according to claim 9, characterized in that said controlled release devices are manufactured by being connected together in rows.