CN1068200A - The quantitative analysis method of growth of spur and bmd and X ray image system - Google Patents
The quantitative analysis method of growth of spur and bmd and X ray image system Download PDFInfo
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- CN1068200A CN1068200A CN 92107606 CN92107606A CN1068200A CN 1068200 A CN1068200 A CN 1068200A CN 92107606 CN92107606 CN 92107606 CN 92107606 A CN92107606 A CN 92107606A CN 1068200 A CN1068200 A CN 1068200A
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- 238000000034 method Methods 0.000 title claims abstract description 23
- 238000004445 quantitative analysis Methods 0.000 title claims description 8
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 50
- 210000004872 soft tissue Anatomy 0.000 claims abstract description 27
- 208000001132 Osteoporosis Diseases 0.000 claims abstract description 20
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 17
- 239000011707 mineral Substances 0.000 claims abstract description 17
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229910052782 aluminium Inorganic materials 0.000 claims abstract description 13
- 238000012113 quantitative test Methods 0.000 claims abstract description 10
- 239000004411 aluminium Substances 0.000 claims abstract description 6
- 230000009466 transformation Effects 0.000 claims abstract description 3
- 208000010392 Bone Fractures Diseases 0.000 claims description 27
- 206010017076 Fracture Diseases 0.000 claims description 27
- 238000005259 measurement Methods 0.000 claims description 12
- 230000037182 bone density Effects 0.000 claims description 5
- 241001465754 Metazoa Species 0.000 claims description 4
- 238000005303 weighing Methods 0.000 claims description 4
- 206010020649 Hyperkeratosis Diseases 0.000 claims description 3
- 238000010606 normalization Methods 0.000 claims description 3
- 229910000737 Duralumin Inorganic materials 0.000 claims description 2
- 229910045601 alloy Inorganic materials 0.000 claims description 2
- 239000000956 alloy Substances 0.000 claims description 2
- 230000003247 decreasing effect Effects 0.000 claims description 2
- 239000004744 fabric Substances 0.000 claims description 2
- 108010048734 sclerotin Proteins 0.000 claims description 2
- 230000001131 transforming effect Effects 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 abstract description 2
- 239000012467 final product Substances 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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Abstract
The invention provides a kind of growth of spur to the fracture object, bone mineral density and osteoporosis person's bone mineral density is carried out the method for quantitative test and is used the X ray image system of this method, this method comparison of standard aluminum wedge as people and fortune thing bone, the fracture object is placed x-ray generator and has between the image intensifier of gamma camera, produce image synchronously with the aluminium wedge, through the A/D conversion, picture frame is stored in display image or printout on the microcomputer, eliminating soft tissue influence and ganmma controller normalized is finished by computer software, can utilize existing X-ray machine transformation to use, cost is low, effective, update for X line machine provides possibility.
Description
The present invention relates to the quantitative analysis method and the X line machine of growth of spur and bmd, particularly a kind ofly can carry out the method for quantitative test and use the required X line machine pattern system of this method growth of spur, bone mineral density and osteoporosis person's the bone mineral density of fracture object.
Use X line machine to observe fracture situation and recovery extent, orthopaedics, dept. of radiology use till today for many years always both at home and abroad, but that observes owing to make film after the fracture object fracture differs longer around the date, employed machine, exposure and washing condition also can not be consistent during film making, so only judge with naked eyes, error is very big, and quantitative test is difficult to carry out especially; Descend for the bone mineral density in the various osteoporosis, be difficult to accurate recognition on the X-ray film equally, the photonic absorption technology and the X line CT of osteoporosis bone measurement amount have been used in recent years, its advantage and restriction are respectively arranged, but instrument and inspection charge are high, and the quantitative test of growth of spur situation is observed after still can not being used at present fracture.
The present invention provides a kind of and is used to observe the quantitative analysis method of growth of spur and bone mineral density and finishes the employed X ray image system of this method for overcoming above-mentioned deficiency.
The present invention is during according to union, with growth of spur, bone content (bone density) increases, fracture site attenuation coefficient under the X line occur to change and during osteoporosis person's osteoporosis, bone mineral content descends, porous spot attenuation coefficient under the X line occurs changing this feature equally, has designed following method:
1, the standard aluminum wedge that selected and human or animal's bone density and average atomic number are close is as the comparison of bone, and the image intensifier (image increase device) that is placed on X line machine is preceding;
2, for getting rid of the interference of live body soft tissue in bone measurement amount, the gray-scale value that attenuation coefficient produced of soft tissue under the X line deducted, obtained the gray-scale value of pure bone;
3, on each width of cloth K line image of same target, be the center with the fracture line, delimitation can all comprise or comprise substantially the corresponding to measured zone of front and back X line image of fracture line;
4, in above-mentioned zone, measure the pure bone average gray in whole broken ends of fractured bone district and the pure bone average gray of the basic identical thickness normal bone matter of knochenbruch phase contrast district respectively nearby, obtain the sclerotin gray scale ratio of the two, if have in the knochenbruch gap hemotoncus, muscle to exist, ask the gray scale ratio again after then deducting hemotoncus, muscle gray scale;
5, in above-mentioned zone, measure the pure bone average gray of pure bone average gray in broken ends of fractured bone district and normal bone matter contrast district, on standard aluminum wedge (similar in appearance to human or animal's bone density), find out the aluminium wedge thickness with last two regional same grayscale values more respectively, go out the bone mineral density ratio in the bone mineral density of tested part and broken ends of fractured bone district and normal district by known aluminium wedge thickness conversion;
6, near osteoporosis person's osteoporosis district or fracture object fracture, be easy to take place the fixed zone of X line image weighing apparatus, osteoporosis region measurement one front and back, perhaps easily respectively measure the fixed zone of a weighing apparatus with the difficult osteoporosis district that takes place, by the not same date variation of successively decreasing of taking the photograph X line image puffs bone mineral density of front and back, or the ratio increase and decrease in two zones, analyze the loose situation of patient's osteoporosis or secondary fracture.
When 7, on not having the X line machine of taking the photograph sheet parameters memorizing function, using, the X line image of different shooting dates, shooting condition is carried out normalization, have comparability to overcome the inconsistent of X line image gray scale, to make between image and image.
For finishing said method, worked out correspondent computer software, and designed the X ray image system, this system is by x ray generator, the image intensifier (image increase device) that has gamma camera, the A/D transducer, picture frame storer and microcomputer are formed, when the patient places between x ray generator and the image intensifier, with place standard aluminum wedge before the image intensifier simultaneously under x-ray bombardment, produce the X line image synchronously, through image intensifier, gamma camera, behind the A/D transducer, can form the bone ash degree image with 256 grades imports and is stored in picture frame storer and the microcomputer, call when measuring, and show or print by the monitor of microcomputer and printer.Native system can use on existing X-ray machine with TV screen, as long as between the image intensifier of X-ray machine and TV screen an interface is set, interface picks out the A/D transducer thus, and picture frame storer and microcomputer get final product.
Below in conjunction with drawings and Examples said method and equipment are described further.
1, aluminium wedge such as Fig. 1 that selects for use extra super duralumin alloy to make, the aluminium wedge can be made into stepped appearance can divide 16 grades, and the thinnest level is 0.5mm, and the thickest level is 8mm, every grade of thick 0.5mm.
2, the specific practice of elimination soft tissue influence is to take the photograph on the X line image the patient, measure the gray scale of reverse S-line of Golden measurement zone bone and soft tissue overlay region earlier, survey near the gray scale of the pure soft tissue area of measurement zone again, then according to location as pure soft tissue area thickness, calculate the attenuation coefficient of the fracture tested pure soft tissue area of object under above-mentioned X line, resemble soft tissue thickness according to this soft tissue at the attenuation coefficient under the X line and bone and side position, soft tissue overlay region, calculate the corresponding gray scale of this overlay region soft tissue and deducted, just obtained the gray scale of the pure bone of measurement zone.
3, normalized method can be selected one and the related zone of fracture earlier on the X line image, by a transforming function transformation function, respectively the same patient's different times that will measure is taken the photograph the X line image then and all transformed to one and realized on the standardized new images of intensity profile.
When 4, measuring shaft fracture, because shaft fracture external callus growth showed increased, during measurement, the bone stump district can be suitably to the soft tissue area expansion, and expansion is eliminated soft tissue gray scale influence back and calculated.
For realizing the employed X ray image system of said method block scheme as shown in Figure 2.X ray generator, image intensifier, A/D transducer, picture frame storer and microcomputer all can adopt the commercially available prod, also can will become one in A/D transducer and picture frame storer (the two is referred to as " the image plate ") microcomputer of packing into.(just being provided with the image board socket in the microcomputer of some model), the monitor of microcomputer can adopt colour or white and black displays.When on having the X-ray machine of TV screen, using this picture system, can between the image intensifier of X-ray machine and TV screen, an interface be set, interface picks out A/D transducer, picture frame storer and microcomputer thus, interface also can be provided with a switch, when needing quantitative test, switch is allocated to A/D transducer branch road, when not needing quantitative test, switch is allocated to former X-ray machine display screen shelves, use the same with former X-ray machine.If the image plate that picks out at interface has the D/A converting means simultaneously, then can utilize the display screen of former X-ray machine to do the image demonstration, can save the monitor of microcomputer.Use this picture system also can take the photograph the X-ray sheet and carry out quantitative test, only X-ray film need be placed on the light box under the gamma camera to get final product former X-ray machine.
Use said method and X ray image system, solved the difficult problem that domestic and international unsolved so far X-ray machine carries out quantitative test to growth of spur, osteoporosis situation, clinical experimental research for various promotion growth of spur and osteoporosis observation, advanced reliable high-precision method and instrument are provided, update for X line machine provides possibility.
Claims (7)
1, a kind of method that growth of spur, bone mineral density and osteoporosis person's bone mineral density of fracture object are carried out quantitative test is characterized in that this method may further comprise the steps:
A. the close standard aluminum wedge of selected and human or animal's bone density and average atomic number is as the comparison of bone, be placed on the image intensifier of X line machine before;
B. the gray-scale value that attenuation coefficient produced of soft tissue under the X line deducted, obtained the gray-scale value of pure bone;
C. on each width of cloth X line image of same target, be the center with the fracture line, delimitation can all comprise or comprise substantially the corresponding to measured zone of front and back X line image of fracture line;
D. at the pure bone average gray of above-mentioned zone, obtain the sclerotin gray scale ratio of the two nearby by the pure bone average gray of measuring whole broken ends of fractured bone district respectively and the basic identical thickness normal bone matter of knochenbruch phase contrast district;
E. on standard aluminum wedge (being equivalent to human or animal's bone density), find out the broken ends of fractured bone district that measures among the d and two pure bone average gray values of contrast district, by the aluminium wedge thickness under these two gray-scale values, converse the bone mineral density ratio in the bone mineral density of tested part and broken ends of fractured bone district and normal district;
F. near osteoporosis person's osteoporosis district or fracture object fracture, be easy to take place the fixed zone of X line image weighing apparatus, osteoporosis region measurement one front and back, perhaps easily respectively measure the fixed zone of a weighing apparatus with the difficult osteoporosis district that takes place, by the not same date variation of successively decreasing of taking the photograph X line image puffs bone mineral density of front and back, or the ratio increase and decrease in two zones, analyze the loose situation of patient's osteoporosis or secondary fracture.
When g. using on not having the X line machine of taking the photograph sheet parameters memorizing function, to different shooting dates, the X line image of shooting condition carries out normalization.
2, quantitative analysis method according to claim 1 is characterized in that the standard aluminum wedge is the stepped appearance that extra super duralumin alloy is made, and divides 16 grades, and the thinnest level is 0.5mm, and the thickest level is 8mm, every grade of thick 0.5mm.
3, quantitative analysis method according to claim 1 and 2, it is characterized in that eliminating the soft tissue influence, be to take the photograph on the X line image at the fracture object, measure the gray scale of reverse S-line of Golden measurement zone bone and soft tissue overlay region earlier, survey near the gray scale of the pure soft tissue area of measurement zone again, then according to the side position as pure soft tissue area thickness, calculate the attenuation coefficient of the fracture tested pure soft tissue area of object under above-mentioned X line, according to this soft tissue soft tissue thickness on the attenuation coefficient under the X line and bone and side position, soft tissue overlay region picture, calculate the corresponding gray scale of this overlay region soft tissue and deducted, just obtained the gray scale of the pure bone of measurement zone.Normalization be on the X line image selected one with the related zone of fracture, by a transforming function transformation function, respectively the same patient's different times that will measure is taken the photograph the X line chart then and is resembled and all transform to one and realized on the standardized new images of intensity profile.
4, quantitative analysis method according to claim 1 and 2, when it is characterized in that measuring the backbone, because shaft fracture external callus growth showed increased, during measurement, the bone stump district can be suitably to the soft tissue area expansion, and expansion is eliminated soft tissue gray scale influence back and is calculated.
5, quantitative analysis method according to claim 3, when it is characterized in that measuring the backbone, when showed increased was measured because the shaft fracture external callus is grown, the bone stump district can be suitably to the soft tissue area expansion, and expansion calculates after eliminating the influence of soft tissue gray scale.
6, a kind of bone mineral density of growth of spur, bone mineral density and osteoporosis person to the fracture object is carried out the employed X line of quantitative test machine pattern system, comprise x ray generator and have the image intensifier of video camera, it is characterized in that behind image intensifier, also being connected to A/D transducer, picture frame storer successively and having display and the microcomputer of printer.
7, X ray image system according to claim 6, it is characterized in that between the image intensifier of existing X-ray machine and display screen, an interface being set with TV screen, pick out A/D transducer, picture frame storer successively and have display and the microcomputer of printer by this interface, interface is provided with a switch.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92107606 CN1068200A (en) | 1992-06-15 | 1992-06-15 | The quantitative analysis method of growth of spur and bmd and X ray image system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92107606 CN1068200A (en) | 1992-06-15 | 1992-06-15 | The quantitative analysis method of growth of spur and bmd and X ray image system |
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| CN1068200A true CN1068200A (en) | 1993-01-20 |
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| CN 92107606 Pending CN1068200A (en) | 1992-06-15 | 1992-06-15 | The quantitative analysis method of growth of spur and bmd and X ray image system |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100360089C (en) * | 1998-05-14 | 2008-01-09 | 通用电气公司 | Correction for ghosting caused by highly attenuating objects |
| CN102217944A (en) * | 2010-04-14 | 2011-10-19 | 深圳市艾克瑞电气有限公司 | Method for measuring bone density by using digital X-ray images |
| CN102258372A (en) * | 2010-05-24 | 2011-11-30 | 北京核海高技术有限公司 | Application of image superposition technology to detection of density values of bone minerals |
| CN107690311A (en) * | 2015-05-07 | 2018-02-13 | 艾姆瓦勒公司 | The method of bone mineral density distribution at least one portion for estimating human skeleton |
| CN108682001A (en) * | 2018-03-30 | 2018-10-19 | 深圳市深图医学影像设备有限公司 | The measurement method and device of bone density |
| CN111481225A (en) * | 2020-06-08 | 2020-08-04 | 北京积水潭医院 | Phantoms and X-ray Imaging Equipment for Bone Density Measurement in X-ray Imaging Equipment |
| CN113491526A (en) * | 2020-04-07 | 2021-10-12 | 辽宁开普医疗系统有限公司 | Bone density correction and measurement method based on DR system |
-
1992
- 1992-06-15 CN CN 92107606 patent/CN1068200A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100360089C (en) * | 1998-05-14 | 2008-01-09 | 通用电气公司 | Correction for ghosting caused by highly attenuating objects |
| CN102217944A (en) * | 2010-04-14 | 2011-10-19 | 深圳市艾克瑞电气有限公司 | Method for measuring bone density by using digital X-ray images |
| CN102258372A (en) * | 2010-05-24 | 2011-11-30 | 北京核海高技术有限公司 | Application of image superposition technology to detection of density values of bone minerals |
| CN107690311A (en) * | 2015-05-07 | 2018-02-13 | 艾姆瓦勒公司 | The method of bone mineral density distribution at least one portion for estimating human skeleton |
| CN107690311B (en) * | 2015-05-07 | 2020-11-24 | 艾姆瓦勒公司 | Method for estimating bone mineral density distribution in at least a portion of the human skeleton |
| CN108682001A (en) * | 2018-03-30 | 2018-10-19 | 深圳市深图医学影像设备有限公司 | The measurement method and device of bone density |
| CN113491526A (en) * | 2020-04-07 | 2021-10-12 | 辽宁开普医疗系统有限公司 | Bone density correction and measurement method based on DR system |
| CN113491526B (en) * | 2020-04-07 | 2023-12-05 | 辽宁开普医疗系统有限公司 | Bone density correction and measurement method based on DR system |
| CN111481225A (en) * | 2020-06-08 | 2020-08-04 | 北京积水潭医院 | Phantoms and X-ray Imaging Equipment for Bone Density Measurement in X-ray Imaging Equipment |
| CN111481225B (en) * | 2020-06-08 | 2025-01-24 | 北京积水潭医院 | Phantom and X-ray imaging device for measuring bone density in X-ray imaging device |
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