CN106308738B - A kind of device and method for glaucoma detection - Google Patents
A kind of device and method for glaucoma detection Download PDFInfo
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- CN106308738B CN106308738B CN201610761245.5A CN201610761245A CN106308738B CN 106308738 B CN106308738 B CN 106308738B CN 201610761245 A CN201610761245 A CN 201610761245A CN 106308738 B CN106308738 B CN 106308738B
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- 238000001514 detection method Methods 0.000 title claims abstract description 58
- 208000010412 Glaucoma Diseases 0.000 title claims abstract description 33
- 238000000034 method Methods 0.000 title abstract description 14
- 238000009434 installation Methods 0.000 claims abstract description 46
- 238000012360 testing method Methods 0.000 claims abstract description 19
- 230000007246 mechanism Effects 0.000 claims abstract description 15
- 238000012544 monitoring process Methods 0.000 claims abstract description 14
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- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
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Abstract
The present invention relates to medical diagnostic techniqu field, specially a kind of device and method for glaucoma detection.A kind of device for glaucoma detection, including table top indication mechanism and Tai Xia testing agencies, and connect the table top indication mechanism and the installation connecting element of the Tai Xia testing agencies；The table top indication mechanism includes fore shell, the image display, camera monitor and the medical display being electrically connected with described image display that are arranged on the fore shell and the monitoring camera-shooting display being electrically connected with the camera monitor；Described image display and the camera monitor are arranged on the fore shell by the first mounting bracket, and the medical display and the monitoring camera-shooting display are arranged on the fore shell by the second mounting bracket.The present invention can mitigate the pain of patient in detection process, and detection speed is fast, time-consuming short, and Detection accuracy is high, additionally it is possible to reasonably sets various specific detection devices, makes detection process easy, hommization.
Description
Technical field
The present invention relates to medical diagnostic techniqu field, specially a kind of device and method for glaucoma detection.
Background technology
Glaucoma is a kind of ophthalmology disease, and it is fallen ill, and rapid, harmfulness is big.Its reason is intraocular pressure intermittently or continually property liter
High level exceedes the degree that eyeball is resistant to and brings infringement to eyeball each several part tissue and visual performance, causes optic nerve
Atrophy, the visual field reduce, hypopsia, blindness be the time sooner or later, can be lost completely in acute attack stage 24-48 hours
It is bright.
Therefore, in time, accurately diagnosis glaucoma is particularly significant, the discovery state of an illness only as early as possible, could take in time
Measure, Authorization Notice No. CN201888807U, bulletin open the Chinese invention patent that day is on July 16th, 2011 disclose it is portable
Formula glaucoma rapid-screening analyzer, it mainly stimulates screen, monitoring camera-shooting to fill by industrial computer, LED brightness controlling devices, the visual field
Put, transponder and printing mechanism into, the industrial computer respectively with LED brightness controlling devices, camera monitoring device, transponder and
Printer connects, and the LED brightness controlling devices stimulate screen connection with light-dividing device and the visual field successively, its by industrial computer with
LED lamp control devices are communicated, and control LED lamp luminous intensities, and according to glaucoma rapid-screening analysis strategy, completion pair
The analysis of testing result.Such detection mode, the stimulation to eyes is very big, and patient is very painful in detection process, detection when
Between it is very long need 30 minutes, the accuracy of detection is not also high, and various equipment are desultorily placed, and is unfavorable for actual inspection
Survey operation.
The content of the invention
The problem of present invention exists for prior art, it is proposed that a kind of pain that can mitigate patient in detection process,
Detection speed is fast, time-consuming short, and Detection accuracy is high, additionally it is possible to reasonably sets various specific detection devices, makes detection process
Easy, the device for being used for glaucoma detection of hommization and the method using device detection glaucoma.
The technical solution adopted for the present invention to solve the technical problems is：A kind of device for glaucoma detection, including
Table top indication mechanism and Tai Xia testing agencies, and connect the installation company of the table top indication mechanism and the Tai Xia testing agencies
Fitting；
The table top indication mechanism includes fore shell, be arranged on image display on the fore shell, camera monitor and
The medical display being electrically connected with described image display and the monitoring camera-shooting being electrically connected with the camera monitor are shown
Device；Described image display and the camera monitor are arranged on the fore shell by the first mounting bracket, and the medical science is shown
Device and the monitoring camera-shooting display are arranged on the fore shell by the second mounting bracket；
The Tai Xia testing agencies include moving body, are arranged on the middle shell on the moving body surface, and are arranged on
Detection control device inside the moving body；
The detection control device includes computer processor and computer storage, the computer processor with it is described
Image display and the medical display are electrically connected with, and control described image display shows the vision thorn for patient view
Swash figure, control the medical display to record detected from the one or more electrodes for being arranged on patient's scalp, response
Shown in the Visual Evoked Potential Signal of the visual stimulus figure, and according to the Visual Evoked Potential Signal in the medical science
Device shows the analysis result of glaucoma；
By the separation grid stimulus signal being arranged in described image display module production occurs for the visual stimulus figure
Raw, the visual stimulus figure includes stimulating graphic model 1, its stimulation time interval ISI=20ms ~ 60ms, grating contrast C
=8% and stimulate graphic model 2, its stimulation time interval ISI=40ms, grating contrast C=5% ~ 20%；It is described to stimulate figure
Shape pattern 1 randomly selects unit provided with stimulation time interval；The stimulation graphic model 2 randomly selects list provided with grating contrast
Member.
The present invention can show multigroup visual stimulus figure using graphic alphanumeric display, and patient is being observed into these figures
Caused Visual Evoked Potential Signal afterwards, by electrode-feedback to computer processor, and doctor's display is set to record and show
Testing result, such mode are detected, the injury very little to eyes, time-consuming short, in addition, in order to concentrate the attention of patient
Power, be also equipped with camera monitor, at the same can be used for doctor monitor patient whether the figure on Observation Figure display.
And reasonably set whole detection devices on detection means, can the arbitrarily detection height of adjusting display device and inspection during detection
Measuring angle, doctor need not follow detection means to shift one's position with patient, and detection is convenient, and detection efficiency is high.
Preferably, the medical display includes VEP logging modle；The VEP is charged to
Module includes the first amplifying circuit, frequency selection circuit, analog to digital conversion circuit, first control circuit and the first wireless transceiver circuit；
First amplifying circuit is connected with being arranged on the electrode of patient's scalp；The frequency selection circuit connects with first amplifying circuit
Connect；Analog-digital conversion circuit as described is connected with the frequency selection circuit；The first control circuit and analog-digital conversion circuit as described and institute
State the connection of the first wireless transceiver circuit；First wireless transceiver circuit is communicated with the computer processor.
Preferably, first amplifying circuit includes first order amplifying circuit, the second level amplification being of coupled connections successively
Circuit and third level amplifying circuit；The first order and third level amplifying circuit are proportional difference amplifying circuit, and described second
Level amplifying circuit is high-pass filtering differential amplifier circuit.
Preferably, the first order amplifying circuit includes first resistor, second resistance, 3rd resistor, the first integrated fortune
Put and the second integrated transporting discharging；The second resistance is connected between positive terminal and the exit of the first integrated transporting discharging；Described 3rd
Resistance is connected between the negative phase end and exit of the second integrated transporting discharging；The first resistor is being connected to the first integrated transporting discharging just
Between the negative phase end of phase end and the second integrated transporting discharging；The negative phase end of first integrated transporting discharging is signal input part, described second
The positive terminal ground connection of integrated transporting discharging；
The second level amplifying circuit includes the 4th resistance, the 5th resistance, the 6th resistance, the 7th resistance, the first electric capacity, the
Two electric capacity and the 3rd integrated transporting discharging；The exit of first integrated transporting discharging passes sequentially through the first electric capacity, the 4th resistance and the 3rd
The negative phase end connection of integrated transporting discharging；The exit of second integrated transporting discharging passes sequentially through the second electric capacity, the 5th resistance and the 3rd
The positive terminal connection of integrated transporting discharging；6th resistance is connected between the negative phase end and exit of the 3rd integrated transporting discharging；It is described
The positive terminal of 3rd integrated transporting discharging passes through the 7th resistance eutral grounding；
The third level amplifying circuit includes the 8th resistance, the 9th resistance and the 4th integrated transporting discharging；Described 3rd integrated fortune
The exit put is connected with the positive terminal of the 4th integrated transporting discharging；The negative phase end of 4th integrated transporting discharging passes through the 9th resistance and
The exit connection of four integrated transporting dischargings；The negative phase end of 4th integrated transporting discharging passes through the 8th resistance eutral grounding；Described 4th is integrated
The exit of amplifier is the output end of signal.
Preferably, analog-digital conversion circuit as described include charge accumulator, current source module, input resistance, comparator, touch
Send out device, counter, discharge module, clock generation module；Analog voltage signal to be converted is by described in input resistance connection
The first input end of comparator, the second input connection reference voltage of the comparator；The input connection of the trigger
The output end of comparator；The output end of the trigger connects the input and discharge module of the counter；The electric charge is deposited
Reservoir is connected between the first input end of the comparator and the first fixed level；The current source module connection comparator
First input end；The discharge module is connected between the first input end of the comparator and the second fixed level；When described
Clock generation module connects trigger and counter.
Preferably, the swept resistance that it is 5-20 K Ω that the input resistance, which is Standard resistance range,.
Preferably, first mounting bracket includes support bar, the support arm being connected with the support bar, with the support
The regulating arm of arm connection, and the mounting head being connected with the regulating arm；Described support arm one end is provided with the socket support bar
Opening, the other end be provided with the threaded openings one for being threadedly coupled the regulating arm；Described regulating arm one end bottom be provided with it is described
Nipple one, the other end that threaded openings one are used cooperatively are provided with the threaded openings two for being threadedly coupled the mounting head；It is described
Mounting head one end bottom is provided with nipple two, the other end being used cooperatively with the threaded openings two and shown provided with installation diagram picture
The installing plate of device.
Preferably, second mounting bracket includes mounting rod, the first support arm being connected with the mounting rod is and described
The first mounting head and the first regulating arm of first support arm connection, and the second mounting head being connected with first regulating arm；
The accent for being socketed the mounting rod is provided among first support arm, both ends have threaded connection first mounting head
With the first hickey and the second hickey of first regulating arm；First regulating arm one end bottom be provided with it is described
The second nipple, the other end that second hickey is used cooperatively are provided with the 3rd screw thread for being threadedly coupled second mounting head
Interface；Second mounting head one end bottom is provided with the 3rd nipple, another being used cooperatively with the 3rd hickey
End is provided with the second installing plate for installing the monitoring camera-shooting display；First mounting head one end bottom is provided with and described first
The first installing plate of the first nipple, the other end provided with the installation medical display that hickey is used cooperatively.
It is and described preferably, the installation connecting element includes the first linkage section being fixedly connected with the top of the middle shell
The 3rd linkage section that middle shell surface is fixedly connected to patient-side, and contact with the middle shell surface engagement and respectively described in connection
First linkage section and the 3rd linkage section both ends and the second linkage section and the 4th linkage section being convexly curved；Described first
If linkage section, second linkage section, the 3rd linkage section and the 4th linkage section are provided with the fore shell connecting side
Dry installation neck；The installation neck includes the elastic telescopic part being connected with bottom land, is arranged at the top of the elastic telescopic part
Contact block, it is arranged on two groups of slide assemblies of neck both sides, and the reset sliding block being connected with the interactive assemblies；The fore shell
With the installation connecting element contact side be provided with it is described installation neck clamping installation fixture block, it is described installation fixture block be provided with it is described
The fixing groove that slide assemblies fix.
A kind of method of glaucoma detection, including：
Step 1：The medical display is connected by electrode and the scalp of patient and shown by described image display
Show visual stimulus figure to obtain Visual Evoked Potential Signal of the patient in response to the visual stimulus figure；
Step 2：DFT is carried out to the Visual Evoked Potential Signal of medical display record, to obtain
The power spectrum of the Visual Evoked Potential Signal；
Step 3：Integral and calculating is carried out to respectively obtain the frequency of original signal to the power spectrum of the Visual Evoked Potential Signal
The frequency of rate and noise, and determine by the frequency of original signal and the frequency of noise the noise of the Visual Evoked Potential Signal
Than；
Step 4：By the signal to noise ratio compared with preset critical；
Step 5：Based on the comparison, the possibility of glaucoma is determined.
The beneficial effects of the invention are as follows：
1. it is simple eye it is actually detected be no more than 1 minute, eyes all detection operation complete be no more than 10 minutes, subject is not easy
Fatigue, it is significantly better than the multifocal ERG detection device detection time of nearly 2 hours；
2. operation and mydriasis need not be approached, reduce the complexity of operation；Graphic interface and computer programing are certainly
Dynamic analysis causes the equipment to be easy to non-expert's level user operation, and operating personnel are not required to especially training or long period of operation experience, met
Grassroots medical worker technical merit present situation；
3. subject and operator are avoided because suitable to maincenter optic nerve path direct measurement using electro physiology means
Should deviation caused by the judgement of horizontal or technology；The accuracy of glaucoma detection is high；
4. can be detected in common clinic, special shielding room is not required to, light, temperature, humidity, fatigue etc. are existed
The disturbing factor easily occurred in other detection means is without specific limitation.
Brief description of the drawings
Fig. 1 is a kind of structural representation of device for glaucoma detection of the present invention；
Fig. 2 is the structural representation of the first mounting bracket in Fig. 1；
Fig. 3 is the structural representation of the second mounting bracket in Fig. 1；
Fig. 4 is the structural representation of installation connecting element in Fig. 1；
Fig. 5 is the structural representation that neck is installed in Fig. 4；
Fig. 6 is a kind of flow chart of method for glaucoma detection of the present invention；
Wherein：1st, table top indication mechanism, 11, fore shell, 12, image display, 13, camera monitor, 14, medical science shows
Device, 15, monitoring camera-shooting display, the 16, first mounting bracket, the 17, second mounting bracket, 2, Tai Xia testing agencies, 21, moving body,
22nd, middle shell, 3, installation connecting element.
Embodiment
Further illustrate technical scheme below in conjunction with the accompanying drawings and by embodiment.
As shown in figure 1, a kind of device for glaucoma detection, including table top indication mechanism 1 and Tai Xia testing agencies 2,
And connect the table top indication mechanism 1 and the installation connecting element 3 of the Tai Xia testing agencies 2.The table top indication mechanism 1 wraps
Include fore shell 11, be arranged on image display 12 on the fore shell 11, camera monitor 13 and with described image display 12
The medical display 14 of electric connection and the monitoring camera-shooting display 15 being electrically connected with the camera monitor 13.Described image
Display 12 and the camera monitor 13 are arranged on the fore shell 11 by the first mounting bracket 16, the medical display 14
It is arranged on the monitoring camera-shooting display 15 by the second mounting bracket 17 on the fore shell 11.
The Tai Xia testing agencies 2 include moving body 21, are arranged on the middle shell 22 on the surface of moving body 21, and
The detection control device being arranged on inside the moving body 21, the bottom of moving body 21 are provided with universal wheel, and vehicle body is provided with handle
Hand, visual electrophysiology detector entirely can arbitrarily be moved, it is easy to detect.
The detection control device includes computer processor and computer storage, the computer processor with it is described
Image display 12 and the medical display 14 are electrically connected with, and the computer processor is stored by being stored in the computer
Software program control in device, control described image display 12 show the visual stimulus figure for patient view, control institute
State medical display 14 record it is being detected from the one or more electrodes for being arranged on patient's scalp, in response to the vision pierce
Swash the Visual Evoked Potential Signal of figure, and green light is shown in the medical display 14 according to the Visual Evoked Potential Signal
The analysis result of eye.The potential response as caused by visual stimulus signal in brain is referred to as VEP, and the application uses
Electrode collects Visual Evoked Potential Signal, amplifies through amplifier, being converted into data signal by digital-to-analogue converter therewith is sent to
Computer carries out storage and data analysis to obtain the possibility of glaucoma.
By the separation grid stimulus signal being arranged in described image display 12 module occurs for the visual stimulus figure
Produce, patient is stimulated using the separation grid graph of uniqueness.When the grid of low spatial frequency is with high temporal frequency inversion flicker,
The visual effect of sighting target will produce stronger effect of stimulation, and the induction for being advantageous to visual signal produces and can distinguish stimulation regarding god
, can using this technology because M cells more early damage in optic nerve lesion disease through M the and P cells in ganglion cell
Early to identify the infringement of M cells, the generation of early stage optic nerve function damage is prompted.The application is by adjusting correlated frequency
Etc. parameter, the two kinds of subgroups of "ON" and "Off" stimulated in M cells can also be further discriminated between, there is provided more fully stimulation mode and
The fine degree of diagnosis.
The visual stimulus figure includes stimulating graphic model 1, its stimulation time interval ISI=20ms ~ 60ms, grating pair
It is more described than degree C=8% and stimulation graphic model 2, its stimulation time interval ISI=40ms, grating contrast C=5% ~ 20%
Graphic model 1 is stimulated to randomly select unit provided with stimulation time interval, it is random that the stimulation graphic model 2 is provided with grating contrast
Choose unit.When selection stimulates graphic model 1, grating contrast C=8%, stimulation time is at intervals of in ISI=20ms ~ 60ms
Arbitrary value, i.e., with 41 submodules；When selection stimulates graphic model 2, stimulation time interval ISI=40ms, grating contrast
Spend for the arbitrary value in C=5% ~ 20%, i.e., with 16 submodules.It can be shown when selecting visual stimulus figure by image
The random call submodule of device 12, each patient can repeatedly call different submodules when detecting vision to improve glaucoma detection
Accuracy.
The medical display 14 includes VEP logging modle；The VEP, which charges to module, to be included
First amplifying circuit, frequency selection circuit, analog to digital conversion circuit, first control circuit and the first wireless transceiver circuit；Described first
Amplifying circuit is connected with being arranged on the electrode of patient's scalp, suitable for electrode detection to Visual Evoked Potential Signal be amplified
Handle to obtain amplified signal；The frequency selection circuit is connected with first amplifying circuit, suitable for being carried out to the amplified signal
Frequency-selecting is handled to obtain frequency selection signal；Analog-digital conversion circuit as described is connected with the frequency selection circuit, suitable for the frequency selection signal
Analog-to-digital conversion process is carried out to obtain digital sampled signal；The first control circuit and analog-digital conversion circuit as described and described the
One wireless transceiver circuit connects, suitable for being communicated with first wireless transceiver circuit；First wireless transceiver circuit is fitted
In being communicated by radio connection with the computer processor.
The VEP of the application, which is charged to, is provided with frequency selection circuit in module, user can set according to the actual requirements
Different frequency collection scopes, so that useful Visual Evoked Potential Signal is located in the range of the frequency collection of setting, thus carry
The high VEP charges to the accuracy of module collection Visual Evoked Potential Signal, prevents Visual Evoked Potential Signal
Distortion.
The first amplifying circuit that VEP is charged in module include be of coupled connections successively first order amplifying circuit,
Second level amplifying circuit and third level amplifying circuit.The first order and third level amplifying circuit are proportional difference amplification electricity
Road, the second level amplifying circuit are high-pass filtering differential amplifier circuit.
The first order amplifying circuit includes first resistor, second resistance, 3rd resistor, the first integrated transporting discharging and the second collection
Into amplifier, the second resistance is connected between positive terminal and the exit of the first integrated transporting discharging；The 3rd resistor is connected to
Between the negative phase end and exit of second integrated transporting discharging；The first resistor is connected to the positive terminal and second of the first integrated transporting discharging
Between the negative phase end of integrated transporting discharging；The negative phase end of first integrated transporting discharging is signal input part, second integrated transporting discharging
Positive terminal is grounded.
The second level amplifying circuit includes the 4th resistance, the 5th resistance, the 6th resistance, the 7th resistance, the first electric capacity, the
Two electric capacity and the 3rd integrated transporting discharging, the exit of first integrated transporting discharging pass sequentially through the first electric capacity, the 4th resistance and the 3rd
The negative phase end connection of integrated transporting discharging；The exit of second integrated transporting discharging passes sequentially through the second electric capacity, the 5th resistance and the 3rd
The positive terminal connection of integrated transporting discharging；6th resistance is connected between the negative phase end and exit of the 3rd integrated transporting discharging；It is described
The positive terminal of 3rd integrated transporting discharging passes through the 7th resistance eutral grounding.
The third level amplifying circuit includes the 8th resistance, the 9th resistance and the 4th integrated transporting discharging, the described 3rd integrated fortune
The exit put is connected with the positive terminal of the 4th integrated transporting discharging；The negative phase end of 4th integrated transporting discharging passes through the 9th resistance and
The exit connection of four integrated transporting dischargings；The negative phase end of 4th integrated transporting discharging passes through the 8th resistance eutral grounding；Described 4th is integrated
The exit of amplifier is the output end of signal.
The first amplifying circuit that the VEP of the application is charged in module can effectively improve vision induced electricity
The multiplication factor of position signal simultaneously can weaken amplification interference of the other elements to Visual Evoked Potential Signal, further increase green grass or young crops
The accuracy of light eye detection.
The resistance of the first resistor is 200 Ω, the resistance of second resistance is 450 Ω, the resistance of 3rd resistor is 450
Ω, the resistance of the 4th resistance are 1.9K Ω, the resistance of the 5th resistance is 1.9K Ω, the resistance of the 6th resistance is 18K Ω, the 7th electricity
The resistance of resistance is 18K Ω, the resistance of the 8th resistance is 1.2K Ω, the resistance of the 9th resistance is 12K Ω, and first under the resistance is put
The amplification effect of big circuit is best.
The analog to digital conversion circuit that VEP is charged in module includes charge accumulator, current source module, input electricity
Resistance, comparator, trigger, counter, discharge module, clock generation module；Analog voltage signal to be converted passes through the input
Resistance connects the first input end of the comparator, the second input connection reference voltage of the comparator；The trigger
Input connection comparator output end；The output end of the trigger connects the input and electric discharge mould of the counter
Block；The charge accumulator is connected between the first input end of the comparator and the first fixed level；The current source mould
Block connects the first input end of comparator；The discharge module is connected to the first input end of the comparator and second and fixes electricity
Between flat；The clock generation module connection trigger and counter；The charge accumulator is electric capacity.The modulus of the application turns
Change that circuit production cost is low, strong antijamming capability, further increase the detection accuracy of glaucoma.
Input resistance in analog to digital conversion circuit is the swept resistance that Standard resistance range is 5-20 K Ω, and input resistance is not solid
Fixed, but can be adjusted according to actually detected environment, prevent that conversion signal distortion is serious, further increase glaucoma
Detection accuracy.
As shown in fig. 4-5, installation connecting element 3 is provided between the fore shell 11 and the middle shell 22.The installation connection
Part 3 includes the first linkage section being fixedly connected with the middle top of shell 22, is fixedly connected with the middle shell 22 towards patient-side
3rd linkage section, and contacted with the middle surface engagement of shell 22 and connect first linkage section respectively and it is described 3rd connect
The second linkage section and the 4th linkage section for connecing section both ends and being convexly curved.Table top indication mechanism 1 is made by installation connecting element 3
It is more convenient with Tai Xia testing agencies 2 installing/dismountings.First linkage section, second linkage section, the 3rd linkage section
And the 4th linkage section is welded to each other successively.During installation, the first linkage section and the 3rd linkage section are fixed on to the conjunction of middle shell
Right position is put, and then fore shell 11 is arranged on to the surface of installation connecting element 3 make the linkage section of fore shell 11 and first, the second linkage section, the
Three linkage sections and the connection of the 4th linkage section, when fore shell 11 will be made to be securely fixed with middle shell 22, will not be shifted over, and being installed not
It can malfunction.
First linkage section, second linkage section, the 3rd linkage section and the 4th linkage section with it is described
The connecting side of fore shell 11 is provided with some installation necks.The installation neck includes the elastic telescopic part being connected with bottom land, is arranged on institute
The contact block at the top of elastic telescopic part is stated, is arranged on two groups of slide assemblies of neck both sides, and is connected with the interactive assemblies
Reset sliding block.
The slide assemblies include the first sliding shoe for being arranged on the guide rail one of bottom land and being arranged on the guide rail one,
The guide rail two being arranged in side wall and the second sliding shoe being arranged on the guide rail two, be arranged on guide rail three on roof with
And the 3rd sliding shoe on the guide rail three is arranged on, first sliding shoe, the second sliding shoe and the 3rd sliding shoe are mutually led
System is slided.
The fore shell 11 is provided with the installation fixture block with the installation neck clamping, institute with the contact side of installation connecting element 3
State installation fixture block and be provided with the fixing groove entered for the 3rd sliding shoe.
During installation, installation card block alignment is first installed into the notch of neck and contacted with contact block, then firmly presses fore shell
11 elasticity of compression extensible members make installation fixture block enter inside neck, while contact block contacts with the first sliding shoe and promotes the first cunning
Motion block promotes the second sliding shoe upward sliding on guide rail two, entered from guide rail one to two Slideslips, the first mobile sliding shoe
One step, which promotes the 3rd sliding shoe to slide and enter in the fixing groove of installation card block on guide rail three, makes fore shell 11 and installation connecting element 3
Securely fix.
During dismounting, sliding block will be resetted to two Slideslips, drive the 3rd sliding shoe to leave the 3rd sliding shoe to two Slideslips
Fixing groove, installation fixture block depart from the 3rd sliding shoe it is spacing after outwards ejected by elastic telescopic part immediately, reach fore shell 11
The purpose separated with installation connecting element 3, the second sliding shoe and the first sliding shoe return to original under the promotion of the 3rd sliding shoe
Position.
The contact block is provided with the circular surface with first shoe contact, and the setting of circular surface reduces two sliding blocks
Between friction, reduce the degree of wear of sliding block.First sliding block, which is provided with, to be contacted with the contact block and is tilted with bottom land
Angle is more than 60 degree of inclined plane, and the circular surface contacted with the second sliding shoe, and inclined-plane sets and increases horizontal component i.e.
The motive force to the first sliding block is increased, the setting of circular surface reduces the friction between two sliding blocks, reduces the mill of sliding block
Damage degree.The second sliding shoe is provided with contacts and is more than with sidewall draft angles 60 degree of inclined plane with first sliding shoe,
With the circular surface contacted with the 3rd sliding shoe, inclined-plane sets to increase vertical stress component and increase and the second sliding block is pushed away
Power, the setting of circular surface reduce the friction between two sliding blocks, reduce the degree of wear of sliding block.3rd sliding shoe
Provided with being contacted with the second sliding shoe and being more than 60 inclined plane with roof inclination angle, inclined-plane sets and increases horizontal component i.e.
Increase the motive force to the 3rd sliding block.
As shown in Fig. 2 first mounting bracket 16 includes support bar, the support arm being connected with the support bar is and described
The regulating arm of support arm connection, and the mounting head being connected with the regulating arm.Described support arm one end is provided with the socket branch
The opening of strut, the other end are provided with the threaded openings one for being threadedly coupled the regulating arm；Described regulating arm one end bottom be provided with
Nipple one, the other end that the threaded openings one are used cooperatively are provided with the threaded openings two for being threadedly coupled the mounting head；
Described mounting head one end bottom is provided with nipple two, the other end being used cooperatively with the threaded openings two and is provided with installation diagram picture
The installing plate of display.
During specific installation, first the threaded openings one of support arm are threadedly coupled with the nipple one of regulating arm, then will
The threaded openings two of regulating arm are threadedly coupled with the nipple two of mounting head, and support arm then is enclosed on into the suitable position of support bar
Put and fix, furthermore adjust the relative angle between support arm and regulating arm and regulating arm and mounting head according to demand, most
Image display is fixedly mounted on a mounting board afterwards.During use, image display and camera monitor can be according to patients
Physical location regulation detection angles, detection and its it is convenient, there is the characteristics of hommization.
As shown in figure 3, second mounting bracket 17 includes mounting rod, the first support arm being connected with the mounting rod, with
The first mounting head and the first regulating arm of the first support arm connection, and the second installation being connected with first regulating arm
Head.The accent for being socketed the mounting rod is provided among first support arm, both ends have threaded connection first peace
Fill the first hickey and the second hickey of head and first regulating arm；First regulating arm one end bottom be provided with
The second nipple, the other end that second hickey is used cooperatively are provided with the 3rd of threaded connection second mounting head
Hickey；Second mounting head one end bottom be provided be used cooperatively with the 3rd hickey the 3rd nipple,
The other end is provided with the second installing plate for installing the monitoring camera-shooting display；First mounting head one end bottom be provided with it is described
The first installing plate of the first nipple, the other end provided with the installation medical display that first hickey is used cooperatively.
During specific installation, first the first hickey of the first nipple of the first mounting head and the first support arm is connected
Connect, the second nipple of the first regulating arm is connected with the second hickey of the first support arm；Then, by the second mounting head
The 3rd nipple be connected with the 3rd hickey of the first regulating arm；Then, that the first support arm is enclosed on into mounting rod is suitable
Position on and it is fixed, furthermore adjust the first support arm and the first regulating arm and the first mounting head according to demand and first adjust
Relative angle between arm and the second mounting head；Finally, medical display is fixedly mounted on the first installing plate, shooting is supervised
Control display is fixedly mounted on the second installing plate.During use, medical display and monitoring camera-shooting display can be according to doctors
The operating position regulation work angle of shield personnel, operation is extremely convenient, can improve the operating efficiency of doctor.
As shown in fig. 6, disclosed herein as well is a kind of glaucoma detection method, including：Step 1：The medical science is shown
Device 14 shows visual stimulus figure to obtain patient by electrode and the connection of the scalp of patient and by described image display 12
In response to the Visual Evoked Potential Signal of the visual stimulus figure；Step 2：The vision of the medical display 14 record is lured
Send out electric potential signal and carry out DFT, to obtain the power spectrum of the Visual Evoked Potential Signal；Step 3：To described
The power spectrum of Visual Evoked Potential Signal carries out integral and calculating to respectively obtain the frequency of the frequency of original signal and noise, and passes through
The frequency of original signal and the frequency of noise determine the signal to noise ratio of the Visual Evoked Potential Signal；Step 4：By the signal to noise ratio with
Preset critical is compared；Step 5：Based on the comparison, the possibility of glaucoma is determined.
The stimulation figure shown by image display 12 excites obtained Visual Evoked Potential Signal data, is shown by medical science
Show that device 14 is recorded and stored in computer storage, and handled followed by discrete Fourier transform (DFT) and profit
With integral algorithm be calculated the signal to noise ratio of Visual Evoked Potential Signal.By the signal to noise ratio calculated compared with critical value
It is high (positive test result) or low (negative testing result) to produce a result-glaucoma probability.This method can automatically remove artefact
With divorced signal, reduce the tedious work and error in judgement of operating personnel.Data can also be being preserved with reference to computer system
While with through printer output testing result, the test result of each eyes of instant playback on computer screen, for operation
Personnel judge in time, decide whether to continue next operation sequence.Whole analysis system enhances man-machine interaction, to detection
As a result criterion is simple and easy, and greatly reduce needs the judgement operation for relying on more professional's experience, detection visitor in the past
The property seen further is lifted.
Embodiment described above is only that the preferred embodiment of the present invention is described, not to the design of the present invention
It is defined with scope.On the premise of design concept of the present invention is not departed from, technical side of the ordinary people in the field to the present invention
The all variations and modifications that case is made, all should drop into protection scope of the present invention, the claimed technology contents of the present invention,
Through all recording in detail in the claims.
Claims (6)
- A kind of 1. device for glaucoma detection, it is characterised in that：Including table top indication mechanism（1）With Tai Xia testing agencies （2）, and the connection table top indication mechanism（1）With the Tai Xia testing agencies（2）Installation connecting element（3）；The table top indication mechanism（1）Including fore shell（11）, it is arranged on the fore shell（11）On image display（12）, shooting Monitor（13）And with described image display（12）The medical display of electric connection（14）With with the camera monitor （13）The monitoring camera-shooting display of electric connection（15）；Described image display（12）With the camera monitor（13）Pass through One mounting bracket（16）It is arranged on the fore shell（11）On, the medical display（14）With the monitoring camera-shooting display（15）It is logical Cross the second mounting bracket（17）It is arranged on the fore shell（11）On；The Tai Xia testing agencies（2）Including moving body（21）, it is arranged on the moving body（21）The middle shell on surface（22）, And it is arranged on the moving body（21）Internal detection control device;The detection control device includes computer processor and computer storage, the computer processor and described image Display（12）And the medical display（14）It is electrically connected with, controls described image display（12）Show and be used for patient view Visual stimulus figure, control the medical display（14）Record is visited from the one or more electrodes for being arranged on patient's scalp Visual Evoked Potential Signal measuring, in response to the visual stimulus figure, and existed according to the Visual Evoked Potential Signal The medical display（14）Show the analysis result of glaucoma；The visual stimulus figure is by being arranged on described image display（12）In separation grid stimulus signal occur module production Raw, the visual stimulus figure includes stimulating graphic model 1, its stimulation time interval ISI=20ms ~ 60ms, grating contrast C =8% and stimulate graphic model 2, its stimulation time interval ISI=40ms, grating contrast C=5% ~ 20%；It is described to stimulate figure Shape pattern 1 randomly selects unit provided with stimulation time interval；The stimulation graphic model 2 randomly selects list provided with grating contrast Member；First mounting bracket（16）Including support bar, the support arm being connected with the support bar, it is connected with the support arm Regulating arm, and the mounting head being connected with the regulating arm；Described support arm one end, which is provided with, is socketed being open, separately for the support bar One end is provided with the threaded openings one for being threadedly coupled the regulating arm；Described regulating arm one end bottom is provided with and the threaded openings one Nipple one, the other end being used cooperatively are provided with the threaded openings two for being threadedly coupled the mounting head；Described mounting head one end Bottom is provided with the nipple two being used cooperatively with the threaded openings two, the other end is provided with the installation of installation image display Plate；Second mounting bracket（17）Including mounting rod, the first support arm being connected with the mounting rod, with the described first support The first mounting head and the first regulating arm of arm connection, and the second mounting head being connected with first regulating arm；Described first The accent for being socketed the mounting rod is provided among support arm, both ends have threaded connection first mounting head and described the The first hickey and the second hickey of one regulating arm；First regulating arm one end bottom is provided with and second screw thread The second nipple, the other end that Interference fit uses are provided with the 3rd hickey for being threadedly coupled second mounting head；Institute State second mounting head one end bottom and be provided with the 3rd nipple being used cooperatively with the 3rd hickey, the other end provided with peace Fill the second installing plate of the monitoring camera-shooting display；First mounting head one end bottom is provided with and first hickey The first nipple, the other end being used cooperatively are provided with the first installing plate for installing the medical display；The installation connecting element（3）Including with the middle shell（22）The first linkage section that top is fixedly connected, with the middle shell （22）The 3rd linkage section being fixedly connected towards patient-side, and with the middle shell（22）Surface engagement is contacted and connected respectively First linkage section and the 3rd linkage section both ends and the second linkage section and the 4th linkage section being convexly curved；It is described First linkage section, second linkage section, the 3rd linkage section and the 4th linkage section and the fore shell（11）Connection Side is provided with some installation necks；The installation neck includes the elastic telescopic part being connected with bottom land, is arranged on the elastic telescopic Contact block at the top of part, it is arranged on two groups of slide assemblies of neck both sides, and the reset sliding block being connected with the slide assemblies； The fore shell（11）With the installation connecting element（3）Contact side is provided with the installation fixture block with the installation neck clamping, the peace The block that is loaded is provided with the fixing groove fixed with the slide assemblies；The slide assemblies include the first sliding shoe for being arranged on the guide rail one of bottom land and being arranged on the guide rail one, set Guide rail two in side wall and the second sliding shoe being arranged on the guide rail two, the guide rail three being arranged on roof and set The 3rd sliding shoe on the guide rail three, first sliding shoe are put, the second sliding shoe and the 3rd sliding shoe mutually pin down cunning It is dynamic.
- A kind of 2. device for glaucoma detection according to claim 1, it is characterised in that：The medical display（14） Including VEP logging modle；The VEP, which charges to module, includes the first amplifying circuit, frequency selection circuit, mould Number change-over circuit, first control circuit and the first wireless transceiver circuit；First amplifying circuit is with being arranged on patient's scalp Electrode connection；The frequency selection circuit is connected with first amplifying circuit；Analog-digital conversion circuit as described and the frequency selection circuit Connection；The first control circuit is connected with analog-digital conversion circuit as described and first wireless transceiver circuit；First nothing Line transmission circuit is communicated with the computer processor.
- A kind of 3. device for glaucoma detection according to claim 2, it is characterised in that：The first amplifying circuit bag Include the first order amplifying circuit being of coupled connections successively, second level amplifying circuit and third level amplifying circuit；The first order and Three-stage amplifier is proportional difference amplifying circuit, and the second level amplifying circuit is high-pass filtering differential amplifier circuit.
- A kind of 4. device for glaucoma detection according to claim 3, it is characterised in that：The first order amplifying circuit Including first resistor, second resistance, 3rd resistor, the first integrated transporting discharging and the second integrated transporting discharging；The second resistance is connected to Between the positive terminal and exit of first integrated transporting discharging；The 3rd resistor is connected to negative phase end and the extraction of the second integrated transporting discharging Between end；The first resistor is connected between the positive terminal of the first integrated transporting discharging and the negative phase end of the second integrated transporting discharging；It is described The negative phase end of first integrated transporting discharging is signal input part, and the positive terminal of second integrated transporting discharging is grounded；The second level amplifying circuit includes the 4th resistance, the 5th resistance, the 6th resistance, the 7th resistance, the first electric capacity, the second electricity Hold and the 3rd integrated transporting discharging；It is integrated that the exit of first integrated transporting discharging passes sequentially through the first electric capacity, the 4th resistance and the 3rd The negative phase end connection of amplifier；It is integrated that the exit of second integrated transporting discharging passes sequentially through the second electric capacity, the 5th resistance and the 3rd The positive terminal connection of amplifier；6th resistance is connected between the negative phase end and exit of the 3rd integrated transporting discharging；Described 3rd The positive terminal of integrated transporting discharging passes through the 7th resistance eutral grounding；The third level amplifying circuit includes the 8th resistance, the 9th resistance and the 4th integrated transporting discharging；3rd integrated transporting discharging Exit is connected with the positive terminal of the 4th integrated transporting discharging；The negative phase end of 4th integrated transporting discharging is collected by the 9th resistance and the 4th Exit into amplifier connects；The negative phase end of 4th integrated transporting discharging passes through the 8th resistance eutral grounding；4th integrated transporting discharging Exit be signal output end.
- A kind of 5. device for glaucoma detection according to claim 2, it is characterised in that：Analog-digital conversion circuit as described bag Include charge accumulator, current source module, input resistance, comparator, trigger, counter, discharge module, clock generation module； Analog voltage signal to be converted connects the first input end of the comparator by the input resistance, and the second of the comparator Input connects reference voltage；The output end of the input connection comparator of the trigger；The output end of the trigger connects Connect the input and discharge module of the counter；The charge accumulator is connected to the first input end and of the comparator Between one fixed level；The first input end of the current source module connection comparator；The discharge module is connected to the ratio Compared between the first input end and the second fixed level of device；The clock generation module connection trigger and counter.
- A kind of 6. device for glaucoma detection according to claim 5, it is characterised in that：The input resistance is resistance Scope is 5-20 K Ω swept resistance.
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| CN201610761245.5A CN106308738B (en) | 2016-08-30 | 2016-08-30 | A kind of device and method for glaucoma detection |
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| CN106308738B true CN106308738B (en) | 2018-02-16 |
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| CN108229545B (en) * | 2017-12-22 | 2021-09-14 | 北京市商汤科技开发有限公司 | Glaucoma diagnosis method and device and electronic equipment |
| CN108413198A (en) * | 2018-05-15 | 2018-08-17 | 郑州大学 | Adaptive pinpoint visual stimulator |
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| WO2003061460A2 (en) * | 2002-01-18 | 2003-07-31 | Universiy Of Iowa Research Foundation | Device and method for optical imaging of retinal function |
| WO2008077177A1 (en) * | 2006-12-22 | 2008-07-03 | Neuro-Insight Pty. Ltd. | A method to evaluate psychological responses to visual objects |
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| US4697598A (en) * | 1985-04-25 | 1987-10-06 | Westinghouse Electric Corp. | Evoked potential autorefractometry system |
| CN1555243A (en) * | 2001-08-07 | 2004-12-15 | ��ϰ�� | Systems and methods for visual inspection |
| CN1829469A (en) * | 2003-06-27 | 2006-09-06 | 胡宗祺 | Apparatus and method for automated process of detection and monitoring of early glaucoma |
| CN1541609A (en) * | 2003-11-06 | 2004-11-03 | 中国科学院上海生命科学研究院 | Intermittent display grating-induced optokinetic detection device for primary open-angle glaucoma |
| CN202859114U (en) * | 2012-09-26 | 2013-04-10 | 湖州美科沃华医疗技术有限公司 | Working table for visual electrophysiological detector |
| CN104771158A (en) * | 2015-04-07 | 2015-07-15 | 四川新源生物电子科技有限公司 | Action potential recorder and closed-loop pain suppression system |
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