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CN1063060C - Compound Chinese medicine preparation for curing traumatic paraplegia and its preparation technology - Google Patents

Compound Chinese medicine preparation for curing traumatic paraplegia and its preparation technology Download PDF

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CN1063060C
CN1063060C CN97100284A CN97100284A CN1063060C CN 1063060 C CN1063060 C CN 1063060C CN 97100284 A CN97100284 A CN 97100284A CN 97100284 A CN97100284 A CN 97100284A CN 1063060 C CN1063060 C CN 1063060C
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CN1160571A (en
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谢忠伟
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Abstract

The present invention relates to a medicine for treating paraplegia, which comprises angelica, tall gastrodis tuber, scorpion, olibanum, hemlock parsley, twotoothed achyranthes root, sweetgum fruit, tuberculate speranskia herb, radix dipsaci from Sichuan of China, deerhorn glue, long-noded pit viper, antelope horn, red sage root, safflower, dragon blood, pangolin scale, raw sichuan axonite root, cortex moutan root-bark of tree peony, sappanwood, eucommia bark, musk, snow lotus herb, gymnadenia tuber, longhairy antenoron herb, deer's sinew, leopard's bone, medicated leaven, milkvetch root, rhizoma corydalis and cape jasmine fruit. The medicine has good therapeutic efficacy for paraplegia, especially traumatic paraplegia caused by various kinds of reasons.

Description

A kind of compound Chinese medicinal preparation and preparation technology thereof who treats traumatic paralysis
The present invention relates to a kind of compound Chinese medicinal preparation for the treatment of paraplegia, specifically be a kind of with the Chinese herbal medicine be raw material according to the Chinese patent medicine that special process is prepared from, can be used for treating various paraplegia, particularly traumatic paralysis, the invention still further relates to the preparation technology of described Chinese patent medicine, belong to the field of Chinese medicines.
Paraplegia, i.e. lower part of the body paralysis makes lower limb unsuccessful again, and it is withered to be commonly called as paralysis.The result of modern medicine study shows, paraplegia neither a kind of independent and concrete disease, and to become what cause be the syndrome of main clinical manifestation with the forfeiture of lower part of the body motor function but traverse sexually transmitted disease (STD) by spinal cord.According to the lesion nature difference, spinal cord traverses the sexually transmitted disease (STD) change can be divided into traumatic and struvite pathological changes two big classes, traumatic spinal cord traverses sexually transmitted disease (STD) and becomes how to be caused by accident that struvite spinal cord traverses the sexually transmitted disease (STD) change and caused that by myelitis, spinal arachnoiditis etc. the two all can cause paraplegia.In general, the above spinal cord of second dorsal vertebra traverses sexually transmitted disease (STD) and becomes and can cause high paraplegia, and the following spinal cord of third dorsal vertebra traverses sexually transmitted disease (STD) and becomes and can cause lower part of the body paraplegia.One of important feature of paralytic patient is that its brain remains intact, and the patient realizes clear, and talk be exactly that the lower part of the body is inactive, defecation is not felt and do not known at the paralysis position, thereby paralytic patient is heavier than hemiplegic patient's psychological burden freely, and is painful unusual.At present, the treatment of paraplegia and malignant tumor is two hang-ups of world medicine.Although paraplegia is not incurable disease, but the quantity of now complete paraplegia being cured is very little.To the treatment of paraplegia, though some treatment measure all is some complementary treatments, for example, the qigong, liquid drugs injection, acupuncture, acusector, massage etc.Up to the present, also there is not a kind of medicine of directly effectively treating paraplegia both at home and abroad.
The object of the invention provides a kind of medicine of effective treatment paraplegia, particularly traumatic paralysis.
Another object of the present invention provides the preparation technology of described treatment paraplegia medicine.
Paralytic patient health lateral symmetry position is useless in unsuccessful, directly influences the normal circulation route of governor vessel, conception vessel.The traditional Chinese medical science " internal diameter " is Sino-Japan: " waist is the kidney mansion, and kidney governing bones, main marrow, department two are just ", day " spleen governing limbs muscle is had one's ideas straightened out in mouth, and its China is at lip, and conception vessel arises from perineum, and row goes into to belong to lip in the abdomen breast " again.So paralytic patient is breathed suffering mostly with two just mistake departments, to superintend and direct, appoint damage, meridians are obstructed, QI and blood blocks suddenly, can not moisten foster extremity, cause numb limbs and tense tendons meciless.What " the kidney being the origin of congenital constitution, and spleen is a source of generating QI and blood, and spleen is the root day after tomorrow " arranged again says that human body lives in the Nature, if all be subjected to the influence of exopathogen at all, and the fortune mistake department of spleen, thereby inappetence then, malnutrition, of flaccid muscles, the atrophy of becoming thin.Again day: liver governing tendons, to have one's ideas straightened out in order, its China is at pawl, and so liver controlling blood is also.Again day: stomach receiving food and drink, digest food, its gas with logical reduce to suitable, so " source of stomach person reservoir of food and drink, six internal organs is also " arranged, day again: " stomach be 12 through the sea " " 12 through all being compiled in stomach ".In a word, concerning paralytic patient, injured after, at liver,kidney,spleen, stomach aspects requisite influence and connection band relation are arranged.
The four diagnostic methods eight according to motherland's medical science are firm, and carry out dialectical opinion and control, be the rule of treatment with causing resuscitation with aromatic drugs, promoting blood circulation to remove obstruction in the collateral, promoting tissue regeneration by removing blood stasis, kidney and spleen invigorating, bone and muscle strengthening, prescription composed as follows, according to certain technology, preparation patent medicine.
The composition of medicine of the present invention is:
Radix Angelicae Sinensis 400-600 weight portion
Rhizoma Gastrodiae 200-400 weight portion
Scorpio 400-600 weight portion
Olibanum 100-300 weight portion
Rhizoma Chuanxiong 300-400 weight portion
Radix Achyranthis Bidentatae 400-600 weight portion
Fructus Liquidambaris 100-300 weight portion
Deep leather 100-300 weight portion
Radix Dipsaci 200-300 weight portion
Colla cornus cervi 400-600 weight portion
Agkistrodon 100-300 weight portion
Cornu Saigae Tataricae 200-400 weight portion
Radix Salviae Miltiorrhizae 800-1200 weight portion
Flos Carthami 80-120 weight portion
Sanguis Draxonis 400-600 weight portion
Squama Manis 300-400 weight portion
Radix Aconiti 100-300 weight portion
Cortex Moutan 400-600 weight portion
Lignum Sappan 400-600 weight portion
Cortex Eucommiae 400-600 weight portion
Moschus 80-120 weight portion
Herba Saussureae Involueratae 1200-1800 weight portion
Fructus Citri Sarcodactylis ginseng 800-1200 weight portion
Herba Lysimachiae 400-600 weight portion
Ligamentum cervi 800-1200 weight portion
Os pardi 800-1200 weight portion
Massa Medicata Fermentata 300-500 weight portion
Radix Astragali 1000-1500 weight portion
Rhizoma Corydalis 200-300 weight portion
Fructus Gardeniae 200-400 weight portion
The best proportioning that medicine of the present invention is formed is:
Radix Angelicae Sinensis 500 weight portions
Rhizoma Gastrodiae 300 weight portions
Scorpio 500 weight portions
Olibanum 200 weight portions
Rhizoma Chuanxiong 350 weight portions
Radix Achyranthis Bidentatae 500 weight portions
Fructus Liquidambaris 200 weight portions
Herba speranskiae tuberculatae 200 weight portions
Radix Dipsaci 250 weight portions
Colla cornus cervi 500 weight portions
Agkistrodon 200 weight portions
Cornu Saigae Tataricae 300 weight portions
Radix Salviae Miltiorrhizae 1000 weight portions
Flos Carthami 100 weight portions
Sanguis Draxonis 500 weight portions
Squama Manis 350 weight portions
Radix Aconiti 200 weight portions
Cortex Moutan 500 weight portions
Lignum Sappan 450 weight portions
The Cortex Eucommiae 500 weight portions
Moschus 100 weight portions
Herba Saussureae Involueratae 1500 weight portions
Fructus Citri Sarcodactylis is joined 1000 weight portions
Herba Lysimachiae 500 weight portions
Ligamentum cervi 1000 weight portions
Os pardi 1000 weight portions
Massa Medicata Fermentata 400 weight portions
The Radix Astragali 1200 weight portions
Rhizoma Corydalis 260 weight portions
Fructus Gardeniae 300 weight portions
Medicine of the present invention can be prepared into any pharmaceutical dosage form that uses clinically that is applicable to according to the preparation process of routine, for example, and pill, tablet, capsule, powder, powder, sublimed preparation, oral liquid etc.The preferred agent of medicine of the present invention is a capsule.
The preparation technology of capsule is as follows:
With Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Liquidambaris, Herba speranskiae tuberculatae, Radix Dipsaci, Cortex Moutan, Radix Salviae Miltiorrhizae, the Radix Astragali, Herba Lysimachiae is pulverized and is superfine end, perhaps grind and be superfine end with ferrum, with Sanguis Draxonis, Squama Manis, Ligamentum cervi, Os pardi is concocted the back pulverizing respectively or is ground the poling smalls, with Rhizoma Corydalis, the Fructus Citri Sarcodactylis ginseng is pulverized and is coarse powder, it is an amount of to add red sand in copper vessel, a proof gold is put in the inside, pure gold size does not influence process of preparing Chinese medicine effect, key is to have when sand system proof gold to exist, to reach the purpose of gold system, the addition of red sand is not advisable can there not to be medical material, the preferred red sand that uses Shanshan is waited to fry and is added Rhizoma Corydalis after red sand boils to the container, the Fructus Citri Sarcodactylis ginseng is fried when extremely Huang Jiao is suitable and is sieved, speed is put into urine of baby boys, waits to soak after 30 minutes that the oven dry back is stand-by again.The concocting method of the used medical material of the present invention is respectively: Massa Medicata Fermentata bran system, and Squama Manis vinegar system, Ligamentum cervi sand system, Os pardi Oleum sesami system, Agkistrodon is used processed with wine.
Above all medicines after concocting, pulverizing, are crossed 60-120 order copper ferrum sieve respectively, incapsulate, for for oral administration.
Medicine of the present invention effect with good curing paraplegia for oral administration is from the beginning in 1984, though the inventor has treated the traumatic paralysis patient that 141 examples have little effect through the elsewhere treatment altogether.The longest 33 years of injured time, the shortest 3 months, its efficacy result was as follows:
Clinical treatment paraplegia curative effect is summed up
Complete paraplegia Immaturity paraplegia Add up to
Number Percentage ratio Number Percentage ratio Number Percentage ratio
Cure 103 73.1% 14 ?9.9% 117 ?83%
Take a turn for the better 18 12.8% 6 ?4.2% 24 ?17%
Invalid Do not have Do not have Do not have
Annotate: above standard is decided according to " clinical disease diagnosis is according to curing the improvement standard " of in February, 1987 promulgation of civitas terrena PLA General Logistics Department Ministry of Public Health.
This standard is:
Cure: muscular strength, sensation, defecation and spinal function are recovered substantially, no complication or cured.
Take a turn for the better: union of fracture, muscular strength, sensation, defecation, urinate and spinal function has improvement, complication such as no pressure ulcer and urinary system infection.
To the treatment of paraplegia, be 1 year the external course of treatment, and domestic is 3-6 month, can reach short treating period, eutherapeutic effect with Drug therapy of the present invention, and have no adverse reaction, and general one month can take effect.The functional training that just can sit within March, stand, walk with the above-mentioned 141 routine paralytic patients of Drug therapy of the present invention.
Medicine of the present invention all has excellent curative to multiple paraplegia, and for example, the paraplegia that myelitis causes particularly has extraordinary curative effect for traumatic paralysis.
Model case
Grandson, the man, 45 years old, married, Jiangsu nationality, kind cattle farm, Hutubi County workman.Readme is (1978) before 12 years, (1 tonnage) come off suddenly and pounded in the shoulder back when repairing harvester, causes fracture of thoracic vertebrae, dislocation, at that time the two numbnesss of lower limbs of i.e. sense, companion's gatism, be sent to Xinjiang Medical College the same day, be diagnosed as breast 12 waists 1 vertebral fracture, dislocation companion paraplegia, after the film making of X line is made a definite diagnosis, the row spinal cord is detected, the vertebral body internal fixation operation, and month cotangent mouth of being in hospital heals and leaves hospital.The hospital of inlanding seeks medical advice and does not all have obvious curative effects and stopped treatment.Sought medical advice in hospital in 29th in December in 1994.Having a medical check-up, growth is normal, nutrition is poor, and question and answer are definite, sanity, and the injury vertebral body is crooked to the left, no tenderness and percussion pain can not be stood, and two lower limb exercises are limited, the serious atrophy of muscle, the pain sensation weakens to disappearance below knee, hypomyotonia, muscular tension " 0 " level, hold up both feet to squat down by both hands over 12 years always and walk, the bilateral physiological reflex disappears, and pathologic reflex is not drawn, be diagnosed as breast 12 waists 1 vertebral body old fracture, companion's paraplegia, pulse condition is heavy thin, tongue fur is light white, and the food of receiving is relatively poor, and night, bedroom still could.Through using Drug therapy of the present invention, the patient can stand and take exercise 2 hours at present, and the training of can taking a step in parallel bars, and two lower limb muscles atrophys have begun to recover.Two just can control 2 hours, and the training that can take the crutches exercise to walk.
Embodiment:
Prescription:
Radix Angelicae Sinensis 500 grams
Rhizoma Gastrodiae 300 grams
Scorpio 500 grams
Olibanum 200 grams
Rhizoma Chuanxiong 350 grams
Radix Achyranthis Bidentatae 500 grams
Fructus Liquidambaris 200 grams
Herba speranskiae tuberculatae 200 grams
Radix Dipsaci 250 grams
Colla cornus cervi 500 grams
Agkistrodon 200 grams
Cornu Saigae Tataricae 300 grams
Radix Salviae Miltiorrhizae 1000 grams
Flos Carthami 100 grams
Sanguis Draxonis 500 grams
Squama Manis 350 grams
Radix Aconiti 200 grams
Cortex Moutan 500 grams
Lignum Sappan 450 grams
The Cortex Eucommiae 500 grams
Moschus 100 grams
Herba Saussureae Involueratae 1500 grams
Fructus Citri Sarcodactylis ginseng 1000 grams
Herba Lysimachiae 500 grams
Ligamentum cervi 1000 grams
Os pardi 1000 grams
Massa Medicata Fermentata 400 grams
The Radix Astragali 1200 grams
Rhizoma Corydalis 260 grams
Fructus Gardeniae 300 grams
It is superfine end that Radix Angelicae Sinensis, Rhizoma Gastrodiae, Rhizoma Chuanxiong, Fructus Liquidambaris, Herba speranskiae tuberculatae, Radix Dipsaci, Cortex Moutan, Radix Salviae Miltiorrhizae, the Radix Astragali, Herba Lysimachiae are pulverized, be ground into superfine end after Rhizoma Gastrodiae, Sanguis Draxonis, Squama Manis, Ligamentum cervi, Os pardi concocted respectively, Massa Medicata Fermentata bran system wherein, Squama Manis vinegar system, Ligamentum cervi sand system, Os pardi Oleum sesami system, Agkistrodon is used processed with wine.It is coarse powder that Rhizoma Corydalis, Fructus Citri Sarcodactylis ginseng are pulverized, it is an amount of to add red sand in copper vessel, a proof gold is put in the inside, to reach the purpose of gold system, the addition of red sand is not advisable can there not to be medical material, waits to fry to add Rhizoma Corydalis, Fructus Citri Sarcodactylis ginseng after red sand boils to the container, fries to yellow and burntly sieves when suitable, speed is put into urine of baby boys, waits to soak after 30 minutes that the oven dry back is stand-by again.
Above all medicines after concocting, pulverizing, are crossed 120 order copper ferrum sieve respectively, incapsulate, promptly.

Claims (4)

1, a kind of medicine for the treatment of paraplegia is characterized in that this medicine made by following component:
Radix Angelicae Sinensis 400-600 weight portion
Rhizoma Gastrodiae 200-400 weight portion
Scorpio 400-600 weight portion
Olibanum 100-300 weight portion
Rhizoma Chuanxiong 300-400 weight portion
Radix Achyranthis Bidentatae 400-600 weight portion
Fructus Liquidambaris 100-300 weight portion
Herba speranskiae tuberculatae 100-300 weight portion
Radix Dipsaci 200-300 weight portion
Colla cornus cervi 400-600 weight portion
Agkistrodon 100-300 weight portion
Cornu Saigae Tataricae 200-400 weight portion
Radix Salviae Miltiorrhizae 800-1200 weight portion
Flos Carthami 80-120 weight portion
Sanguis Draxonis 400-600 weight portion
Squama Manis 300-400 weight portion
Radix Aconiti 100-300 weight portion
Cortex Moutan 400-600 weight portion
Lignum Sappan 400-600 weight portion
Cortex Eucommiae 400-600 weight portion
Moschus 80-120 weight portion
Herba Saussureae Involueratae 1200-1800 weight portion
Fructus Citri Sarcodactylis ginseng 800-1200 weight portion
Herba Lysimachiae 400-600 weight portion
Ligamentum cervi 800-1200 weight portion
Os pardi 800-1200 weight portion
Massa Medicata Fermentata 300-500 weight portion
Radix Astragali 1000-1500 weight portion
Rhizoma Corydalis 200-300 weight portion
Fructus Gardeniae 200-400 weight portion
2, medicine according to claim 1 is characterized in that this medicine made by following component:
Radix Angelicae Sinensis 500 weight portions
Rhizoma Gastrodiae 300 weight portions
Scorpio 500 weight portions
Olibanum 200 weight portions
Rhizoma Chuanxiong 350 weight portions
Radix Achyranthis Bidentatae 500 weight portions
Fructus Liquidambaris 200 weight portions
Herba speranskiae tuberculatae 200 weight portions
Radix Dipsaci 250 weight portions
Colla cornus cervi 500 weight portions
Agkistrodon 200 weight portions
Cornu Saigae Tataricae 300 weight portions
Radix Salviae Miltiorrhizae 1000 weight portions
Flos Carthami 100 weight portions
Sanguis Draxonis 500 weight portions
Squama Manis 350 weight portions
Radix Aconiti 200 weight portions
Cortex Moutan 500 weight portions
Lignum Sappan 450 weight portions
The Cortex Eucommiae 500 weight portions
Moschus 100 weight portions
Herba Saussureae Involueratae 1500 weight portions
Fructus Citri Sarcodactylis is joined 1000 weight portions
Herba Lysimachiae 500 weight portions
Ligamentum cervi 1000 weight portions
Os pardi 1000 weight portions
Massa Medicata Fermentata 400 weight portions
The Radix Astragali 1200 weight portions
Rhizoma Corydalis 260 weight portions
Fructus Gardeniae 300 weight portions
3, medicine according to claim 1 and 2, the dosage form that it is characterized in that this medicine is a capsule.
4, a kind of preparation method for the treatment of the paraplegia medicine is characterized in that it is made by following component and technology:
Radix Angelicae Sinensis 400-600 weight portion
Rhizoma Gastrodiae 200-400 weight portion
Scorpio 400-600 weight portion
Olibanum 100-300 weight portion
Rhizoma Chuanxiong 300-400 weight portion
Radix Achyranthis Bidentatae 400-600 weight portion
Fructus Liquidambaris 100-300 weight portion
Herba speranskiae tuberculatae 100-300 weight portion
Radix Dipsaci 200-300 weight portion
Colla cornus cervi 400-600 weight portion
Agkistrodon 100-300 weight portion
Cornu Saigae Tataricae 200-400 weight portion
Radix Salviae Miltiorrhizae 800-1200 weight portion
Flos Carthami 80-120 weight portion
Sanguis Draxonis 400-600 weight portion
Squama Manis 300-400 weight portion
Radix Aconiti 100-300 weight portion
Cortex Moutan 400-600 weight portion
Lignum Sappan 400-600 weight portion
Cortex Eucommiae 400-600 weight portion
Moschus 80-120 weight portion
Herba Saussureae Involueratae 1200-1800 weight portion
Fructus Citri Sarcodactylis ginseng 800-1200 weight portion
Herba Lysimachiae 400-600 weight portion
Ligamentum cervi 800-1200 weight portion
Os pardi 800-1200 weight portion
Massa Medicata Fermentata 300-500 weight portion
Radix Astragali 1000-1500 weight portion
Rhizoma Corydalis 200-300 weight portion
Fructus Gardeniae 200-400 weight portion
With Radix Angelicae Sinensis, Rhizoma Gastrodiae, Rhizoma Chuanxiong, Fructus Liquidambaris, Herba speranskiae tuberculatae, Radix Dipsaci, Cortex Moutan, Radix Salviae Miltiorrhizae, the Radix Astragali, Herba Lysimachiae is pulverized and is superfine end, perhaps grind and be superfine end with ferrum, with Sanguis Draxonis, Squama Manis, Ligamentum cervi, Os pardi is concocted the back pulverizing respectively or is ground the poling smalls, with Rhizoma Corydalis, the Fructus Citri Sarcodactylis ginseng is pulverized and is coarse powder, it is an amount of to add red sand in copper vessel, and a proof gold is put in the inside, to reach the purpose of gold system, the addition of red sand is not advisable can there not to be medical material, wait to fry and add Rhizoma Corydalis after red sand boils to the container, the Fructus Citri Sarcodactylis ginseng is fried when extremely Huang Jiao is suitable and is sieved, and speed is put into urine of baby boys, wait to soak and dry back Qi Zhong Zhong song bran system of stand-by, Squama Manis vinegar system, Ligamentum cervi sand system after 30 minutes again, Os pardi Oleum sesami system, Agkistrodon is used processed with wine, with above all medicines through concocting, after the pulverizing, cross 60-120 order copper ferrum sieve respectively, incapsulate, promptly.
CN97100284A 1997-01-23 1997-01-23 Compound Chinese medicine preparation for curing traumatic paraplegia and its preparation technology Expired - Lifetime CN1063060C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN97100284A CN1063060C (en) 1997-01-23 1997-01-23 Compound Chinese medicine preparation for curing traumatic paraplegia and its preparation technology

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Application Number Priority Date Filing Date Title
CN97100284A CN1063060C (en) 1997-01-23 1997-01-23 Compound Chinese medicine preparation for curing traumatic paraplegia and its preparation technology

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CN1063060C true CN1063060C (en) 2001-03-14

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CN103083518A (en) * 2012-12-28 2013-05-08 青岛爱维互动信息技术有限公司 Tibetan medicine patch for treating wound

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1102588A (en) * 1994-08-18 1995-05-17 哈尔滨市卫健骨伤截瘫病研究所 Paraplegia medicinal capsule

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1102588A (en) * 1994-08-18 1995-05-17 哈尔滨市卫健骨伤截瘫病研究所 Paraplegia medicinal capsule

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
《上海中医药杂志》,1985年第11期 1985.1.1 谢文正:"加味健步丸治疗进行性肌萎缩脊髓侧索硬化症" *

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