CN106265277A - 儿童洗发露及其制备方法 - Google Patents
儿童洗发露及其制备方法 Download PDFInfo
- Publication number
- CN106265277A CN106265277A CN201610766224.2A CN201610766224A CN106265277A CN 106265277 A CN106265277 A CN 106265277A CN 201610766224 A CN201610766224 A CN 201610766224A CN 106265277 A CN106265277 A CN 106265277A
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- Prior art keywords
- extract
- sodium
- shampoo
- children
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- -1 oleoyl amine Chemical class 0.000 claims abstract description 77
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 49
- 239000000284 extract Substances 0.000 claims abstract description 45
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims abstract description 34
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 claims abstract description 34
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims abstract description 32
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 31
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- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 claims abstract description 18
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- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 15
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims abstract description 15
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- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 claims abstract 4
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Abstract
本发明公开了一种儿童洗发露及其制备方法，所述儿童洗发露由下述原料制备而成：水、月桂醇聚醚硫酸酯钠、乙二醇二硬脂酸、椰油酰胺MEA、甜菜碱类表面活性剂、氯化钠、聚二甲基硅氧烷醇、聚二甲基硅氧烷、卡波姆、水解丝胶蛋白、齿缘墨角藻提取物、泡叶藻提取物、刺海门冬提取物、山梨醇、香精、氨端聚二甲基硅氧烷、瓜尔胶羟丙基三甲基氯化铵、氢氧化钠、甲基氯异噻唑啉酮、甲基异噻唑啉酮、苯氧乙醇、EDTA四钠、柠檬酸。本发明儿童洗发露，蕴含多种天然成分，给予孩子三重爱护：舒柔、滋润、保护，帮助有效洁净头皮头发的同时，水润头皮，柔亮发丝，令孩子的头发柔润散发光泽。
Description
技术领域
本发明涉及日用化工技术领域，具体涉及一种儿童洗发露及其制备方法。
背景技术
随着人类工业化进程的加速，大气中污染成分变得越来越多，例如汽车尾气以及雾霾中所含有的化学成分非常复杂，从而对人体的头发、头皮也带来更多的威胁。
洗发露是家庭洗浴用品之一。目前市场上销售的洗发露用品品种繁多，品质差异也大。通常只具有洗涤效果，功能单一。并且，传统洗发露为了提高清洁力及去油能力，加入了大量碱性极强的表面活性剂，发泡剂，皂基等成分，而人体的皮肤却是弱酸性的，长时间使用会刺激皮肤。更严重的是，皮肤的皮脂膜也会被破坏。一旦失去皮脂膜，皮肤很容易受到外界伤害。
儿童洗发露需要专业研制，儿童皮肤娇嫩，不能使用成人的洗化用品，否则会伤害皮肤，而且成人洗化用品中含有的化学物质会影响儿童健康。
发明内容
针对现有技术中存在的上述不足，本发明所要解决的技术问题之一是提供一种儿童洗发露。
本发明的解决的技术问题之二是提供一种儿童洗发露的制备方法。
本发明目的是通过如下技术方案实现的：
一种儿童洗发露，由下述原料制备而成：水、月桂醇聚醚硫酸酯钠、乙二醇二硬脂酸、椰油酰胺MEA、甜菜碱类表面活性剂、氯化钠、聚二甲基硅氧烷醇、聚二甲基硅氧烷、卡波姆、水解丝胶蛋白、齿缘墨角藻提取物、泡叶藻提取物、刺海门冬提取物、山梨醇、香精、氨端聚二甲基硅氧烷、瓜尔胶羟丙基三甲基氯化铵、氢氧化钠、甲基氯异噻唑啉酮、甲基异噻唑啉酮、苯氧乙醇、EDTA四钠、柠檬酸。
一种儿童洗发露，由下述重量份的原料制备而成：月桂醇聚醚硫酸酯钠45-55份、乙二醇二硬脂酸15-25份、椰油酰胺MEA 35-45份、甜菜碱类表面活性剂45-55份、氯化钠1-10份、聚二甲基硅氧烷醇1-10份、聚二甲基硅氧烷1-10份、卡波姆5-15份、水解丝胶蛋白15-25份、齿缘墨角藻提取物1-10份、泡叶藻提取物1-10份、刺海门冬提取物1-10份、山梨醇5-15份、氨端聚二甲基硅氧烷1-10份、瓜尔胶羟丙基三甲基氯化铵5-15份、氢氧化钠1-10份、甲基氯异噻唑啉酮0.1-1份、甲基异噻唑啉酮0.1-1份、苯氧乙醇1-10份、EDTA四钠1-10份、柠檬酸1-10份、香精0.1-1份、水700-900份。
优选地，所述的香精为香兰素、柠檬香精、薄荷香精、薰衣草香精、玫瑰香精等。
优选地，所述的甜菜碱类表面活性剂为椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱中一种或多种的混合物。
更优选地，所述的甜菜碱类表面活性剂由椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱混合而成，所述椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱的质量比为(1-3)：(1-3)：(1-3)。
本发明还提供了上述儿童洗发露的制备方法，包括以下步骤：
将水加热至65-85℃，搅拌条件下依次加入月桂醇聚醚硫酸酯钠、乙二醇二硬脂酸、椰油酰胺MEA、甜菜碱类表面活性剂、聚二甲基硅氧烷醇、聚二甲基硅氧烷、卡波姆、氨端聚二甲基硅氧烷、瓜尔胶羟丙基三甲基氯化铵搅拌混合均匀，降温至45-55℃，再依次加入山梨醇、香精、甲基氯异噻唑啉酮、甲基异噻唑啉酮、苯氧乙醇、EDTA四钠、柠檬酸、氢氧化钠、氯化钠、水解丝胶蛋白、齿缘墨角藻提取物、泡叶藻提取物、刺海门冬提取物搅拌混合均匀即得。
具体的，在本发明中：
柠檬香精，本发明实施例中采用上海皓月日化有限公司提供的柠檬香精。
椰油酰胺丙基甜菜碱，CAS号：86438-79-1。
3-磺丙基十六烷基二甲甜菜碱，CAS号：2281-11-0。
油酰胺丙基甜菜碱，CAS号：25054-76-6。
乙二醇二硬脂酸，CAS号：627-83-8。
聚二甲基硅氧烷醇，CAS号：68938-54-5，本发明实施例中采用道康宁公司提供的型号为PMX-1403聚二甲基硅氧烷醇。
聚二甲基硅氧烷，CAS号：9016-00-6。
卡波姆，CAS号：76050-42-5。本发明实施例中采用美国路润博(原诺誉)公司提供的卡波姆940。
水解丝胶蛋白，本发明实施例中采用专利申请号201310511239.0中实施例二的方法制备。
氨端聚二甲基硅氧烷，CAS号：71750-80-6，本发明实施例中采用广州市馨雅化工有限公司提供的氨端聚二甲基硅氧烷TCN-620。
瓜尔胶羟丙基三甲基氯化铵，CAS号：65497-29-2，本发明实施例中采用鱼台县海纳环保科技有限公司提供的瓜尔胶羟丙基三甲基氯化铵C-14S。
苯氧乙醇，即乙二醇苯醚，CAS号：122-99-6。
月桂醇聚醚硫酸酯钠，CAS号：9004-82-4。本发明实施例中采用日本花王公司提供的型号为EMAL 270S的月桂醇聚醚硫酸酯钠。
椰油酰胺MEA，即椰油酸单乙醇酰胺，CAS号：68140-00-1。本发明实施例中采用四川花语精细化工有限公司提供的FS600-CMEA椰油酸单乙醇酰胺(不含甘油)。
EDTA四钠，即乙二胺四乙酸四钠，CAS号：64-02-8。
氯化钠，CAS号：7647-14-5。
柠檬酸，CAS号：77-92-9。
氢氧化钠，CAS号：1310-73-2。
甲基氯异噻唑啉酮，CAS号：26172-55-4。
甲基异噻唑啉酮，CAS号：2682-20-4。
山梨醇，又称D-山梨糖醇，CAS号：50-70-4。
齿缘墨角藻提取物，英文名称：Fucus Serratus Extrac，来源于布列坦尼地区的齿缘墨角藻，当地人称为“黄金海藻”。该藻提取物具有增强纤维原细胞活力，保护线粒体细胞，促进皮肤呼吸，为肌肤带来强大保湿功效，活化肌肤储水功能，亦可促进组织再生，增加细胞活力恢复皮肤生机，促进肌肤的新陈代谢，有效对抗自由基、对抗细胞老化，同时释放活性能量，改善干燥、预防细纹、皱纹产生，延缓皮肤衰老。齿缘墨角藻提取物可以制备或购买得到，制备方法可以为常规的水提法或醇提法，比如将齿缘墨角藻清洗粉碎后按照固液比(g/ml)1:10-1:30浸入质量分数为95％乙醇中，浸泡8-12h，加热回流4-6h，冷却，过滤，将滤液浓缩后，冻干成粉末。本发明中所使用的齿缘墨角藻提取物是购买自南京泽朗医药科技有限公司，规格为10:1，即10g齿缘墨角藻提取出的1g齿缘墨角藻提取物。
泡叶藻提取物，英文名称：Ascophyllum Nodosum Extract，具有抗肿瘤、抗病毒、抗菌、消除自由基、抗氧化功效。泡叶藻提取物可以制备或购买得到，制备方法可以为常规的水提法或醇提法，比如将泡叶藻清洗粉碎后按照固液比(g/ml)1:10-1:30浸入质量分数为95％乙醇中，浸泡8-12h，加热回流4-6h，冷却，过滤，将滤液浓缩后，冻干成粉末。本发明中所使用的泡叶藻提取物是购买自西安万方生物科技有限公司，规格为10:1，即10g泡叶藻提取出的1g泡叶藻提取物。
刺海门冬海藻提取物，英文名称：Asparagopsis Armata Extract，富含活性硅，能有效优化皮肤细胞新陈代谢，具有皮肤重建、脂肪分解、抵抗水肿、肤质保湿功效。刺海门冬海藻提取物可以制备或购买得到，制备方法可以为常规的水提法或醇提法，比如将刺海门冬海藻清洗粉碎后按照固液比(g/ml)1:10-1:30浸入质量分数为95％乙醇中，浸泡8-12h，加热回流4-6h，冷却，过滤，将滤液浓缩后，冻干成粉末。本发明中所使用的刺海门冬海藻提取物是购买自爱西美(EXSYMOL)公司，规格为10:1，即10g刺海门冬海藻提取物提取出的1g刺海门冬海藻提取物。
本发明儿童洗发露，蕴含多种天然成分，给予孩子三重爱护：舒柔、滋润、保护，帮助有效洁净头皮头发的同时，水润头皮，柔亮发丝，令孩子的头发柔润散发光泽。
具体实施方式
下面结合实施例对本发明做进一步的说明，以下所述，仅是对本发明的较佳实施例而已，并非对本发明做其他形式的限制，任何熟悉本专业的技术人员可能利用上述揭示的技术内容加以变更为同等变化的等效实施例。凡是未脱离本发明方案内容，依据本发明的技术实质对以下实施例所做的任何简单修改或等同变化，均落在本发明的保护范围内。
实施例1
儿童洗发露原料(重量份)：月桂醇聚醚硫酸酯钠50份、乙二醇二硬脂酸20份、椰油酰胺MEA 40份、甜菜碱类表面活性剂51份、氯化钠5份、聚二甲基硅氧烷醇3份、聚二甲基硅氧烷2份、卡波姆7份、水解丝胶蛋白20份、齿缘墨角藻提取物4份、泡叶藻提取物4份、刺海门冬提取物4份、山梨醇10份、氨端聚二甲基硅氧烷2份、瓜尔胶羟丙基三甲基氯化铵10份、氢氧化钠2份、甲基氯异噻唑啉酮0.15份、甲基异噻唑啉酮0.15份、苯氧乙醇3份、EDTA四钠1.2份、柠檬酸4份、柠檬香精0.18份、水800份。
所述的甜菜碱类表面活性剂由椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱按质量比为1：1：1搅拌混合均匀得到。
上述儿童洗发露的制备方法，包括以下步骤：
将水加热至75℃，500转/分搅拌条件下依次加入月桂醇聚醚硫酸酯钠、乙二醇二硬脂酸、椰油酰胺MEA、甜菜碱类表面活性剂、聚二甲基硅氧烷醇、聚二甲基硅氧烷、卡波姆、氨端聚二甲基硅氧烷、瓜尔胶羟丙基三甲基氯化铵搅拌混合均匀，降温至48℃，再依次加入山梨醇、柠檬香精、甲基氯异噻唑啉酮、甲基异噻唑啉酮、苯氧乙醇、EDTA四钠、柠檬酸、氢氧化钠、氯化钠、水解丝胶蛋白、齿缘墨角藻提取物、泡叶藻提取物、刺海门冬提取物搅拌混合均匀。得到实施例1的儿童洗发露。
实施例2
儿童洗发露原料(重量份)：月桂醇聚醚硫酸酯钠50份、乙二醇二硬脂酸20份、椰油酰胺MEA 40份、甜菜碱类表面活性剂51份、氯化钠5份、聚二甲基硅氧烷醇3份、聚二甲基硅氧烷2份、卡波姆7份、水解丝胶蛋白20份、齿缘墨角藻提取物6份、泡叶藻提取物6份、山梨醇10份、氨端聚二甲基硅氧烷2份、瓜尔胶羟丙基三甲基氯化铵10份、氢氧化钠2份、甲基氯异噻唑啉酮0.15份、甲基异噻唑啉酮0.15份、苯氧乙醇3份、EDTA四钠1.2份、柠檬酸4份、柠檬香精0.18份、水800份。
所述的甜菜碱类表面活性剂由椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱按质量比为1：1：1搅拌混合均匀得到。
上述儿童洗发露的制备方法，包括以下步骤：
将水加热至75℃，500转/分搅拌条件下依次加入月桂醇聚醚硫酸酯钠、乙二醇二硬脂酸、椰油酰胺MEA、甜菜碱类表面活性剂、聚二甲基硅氧烷醇、聚二甲基硅氧烷、卡波姆、氨端聚二甲基硅氧烷、瓜尔胶羟丙基三甲基氯化铵搅拌混合均匀，降温至48℃，再依次加入山梨醇、柠檬香精、甲基氯异噻唑啉酮、甲基异噻唑啉酮、苯氧乙醇、EDTA四钠、柠檬酸、氢氧化钠、氯化钠、水解丝胶蛋白、齿缘墨角藻提取物、泡叶藻提取物搅拌混合均匀。得到实施例2的儿童洗发露。
实施例3
儿童洗发露原料(重量份)：月桂醇聚醚硫酸酯钠50份、乙二醇二硬脂酸20份、椰油酰胺MEA 40份、甜菜碱类表面活性剂51份、氯化钠5份、聚二甲基硅氧烷醇3份、聚二甲基硅氧烷2份、卡波姆7份、水解丝胶蛋白20份、齿缘墨角藻提取物6份、刺海门冬提取物6份、山梨醇10份、氨端聚二甲基硅氧烷2份、瓜尔胶羟丙基三甲基氯化铵10份、氢氧化钠2份、甲基氯异噻唑啉酮0.15份、甲基异噻唑啉酮0.15份、苯氧乙醇3份、EDTA四钠1.2份、柠檬酸4份、柠檬香精0.18份、水800份。
所述的甜菜碱类表面活性剂由椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱按质量比为1：1：1搅拌混合均匀得到。
上述儿童洗发露的制备方法，包括以下步骤：
将水加热至75℃，500转/分搅拌条件下依次加入月桂醇聚醚硫酸酯钠、乙二醇二硬脂酸、椰油酰胺MEA、甜菜碱类表面活性剂、聚二甲基硅氧烷醇、聚二甲基硅氧烷、卡波姆、氨端聚二甲基硅氧烷、瓜尔胶羟丙基三甲基氯化铵搅拌混合均匀，降温至48℃，再依次加入山梨醇、柠檬香精、甲基氯异噻唑啉酮、甲基异噻唑啉酮、苯氧乙醇、EDTA四钠、柠檬酸、氢氧化钠、氯化钠、水解丝胶蛋白、齿缘墨角藻提取物、刺海门冬提取物搅拌混合均匀。得到实施例3的儿童洗发露。
实施例4
儿童洗发露原料(重量份)：月桂醇聚醚硫酸酯钠50份、乙二醇二硬脂酸20份、椰油酰胺MEA 40份、甜菜碱类表面活性剂51份、氯化钠5份、聚二甲基硅氧烷醇3份、聚二甲基硅氧烷2份、卡波姆7份、水解丝胶蛋白20份、泡叶藻提取物6份、刺海门冬提取物6份、山梨醇10份、氨端聚二甲基硅氧烷2份、瓜尔胶羟丙基三甲基氯化铵10份、氢氧化钠2份、甲基氯异噻唑啉酮0.15份、甲基异噻唑啉酮0.15份、苯氧乙醇3份、EDTA四钠1.2份、柠檬酸4份、柠檬香精0.18份、水800份。
所述的甜菜碱类表面活性剂由椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱按质量比为1：1：1搅拌混合均匀得到。
上述儿童洗发露的制备方法，包括以下步骤：
将水加热至75℃，500转/分搅拌条件下依次加入月桂醇聚醚硫酸酯钠、乙二醇二硬脂酸、椰油酰胺MEA、甜菜碱类表面活性剂、聚二甲基硅氧烷醇、聚二甲基硅氧烷、卡波姆、氨端聚二甲基硅氧烷、瓜尔胶羟丙基三甲基氯化铵搅拌混合均匀，降温至48℃，再依次加入山梨醇、柠檬香精、甲基氯异噻唑啉酮、甲基异噻唑啉酮、苯氧乙醇、EDTA四钠、柠檬酸、氢氧化钠、氯化钠、水解丝胶蛋白、泡叶藻提取物、刺海门冬提取物搅拌混合均匀。得到实施例4的儿童洗发露。
实施例5
与实施例1基本相同，区别仅仅在于：所述的甜菜碱类表面活性剂由3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱按质量比为1：1搅拌混合均匀得到。得到实施例5的儿童洗发露。
实施例6
与实施例1基本相同，区别仅仅在于：所述的甜菜碱类表面活性剂由椰油酰胺丙基甜菜碱、油酰胺丙基甜菜碱按质量比为1：1搅拌混合均匀得到。得到实施例6的儿童洗发露。
实施例7
与实施例1基本相同，区别仅仅在于：所述的甜菜碱类表面活性剂由椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱按质量比为1：1搅拌混合均匀得到。得到实施例7的儿童洗发露。
测试例1
按照《洗发露去屑效果检测评价方法的建立及应用研究》所公开的方法对实施例1-7制得的洗发露进行抑菌环直径测试，对洗发露产品的去屑功效进行评价。抑菌环直径越大，去屑效果越好。测试数据见表1。
其中，“洗发露去屑效果检测评价方法的建立及应用研究”，何方、王坦、贾泽宝、洪晓鹏、彭谨，丝宝日化有限公司研发部，日用化学品科学，2009年第11期。
表1：去屑功效测试数据表
| 抑菌环直径，mm | |
| 实施例1 | 23.5 |
| 实施例2 | 18.7 |
| 实施例3 | 19.5 |
| 实施例4 | 18.8 |
| 实施例5 | 20.2 |
| 实施例6 | 19.6 |
| 实施例7 | 20.1 |
比较实施例1与实施例2-4，实施例1(齿缘墨角藻提取物、泡叶藻提取物、刺海门冬提取物复配)去屑功效明显优于实施例2-4(齿缘墨角藻提取物、泡叶藻提取物、刺海门冬提取物中任意二者复配)；比较实施例1与实施例5-7，实施例1(椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱复配)去屑功效明显优于实施例5-7(椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱中任意二者复配)。
测试例2
将实施例1-7制得的儿童洗发露，分别用深褐色玻璃瓶进行灌装，敞开瓶盖，置于环境温度40℃、相对湿度85％环境下保藏90天，然后进行金黄色葡萄球菌(ATCC 6538)菌落总数测试，参照GBT 4789.2-2008食品卫生微生物学检验菌落总数测定。具体测试结果见表2。
表2：菌落总数测试表
| 金黄色葡萄球菌菌落总数，cfu/g | |
| 实施例1 | 253 |
| 实施例2 | 783 |
| 实施例3 | 767 |
| 实施例4 | 763 |
| 实施例5 | 572 |
| 实施例6 | 584 |
| 实施例7 | 559 |
比较实施例1与实施例2-4，实施例1(齿缘墨角藻提取物、泡叶藻提取物、刺海门冬提取物复配)防腐性能明显优于实施例2-4(齿缘墨角藻提取物、泡叶藻提取物、刺海门冬提取物中任意二者复配)；比较实施例1与实施例5-7，实施例1(椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱复配)防腐性能明显优于实施例5-7(椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱中任意二者复配)。
Claims (5)
1.一种儿童洗发露，其特征在于，由下述原料制备而成：水、月桂醇聚醚硫酸酯钠、乙二醇二硬脂酸、椰油酰胺MEA、甜菜碱类表面活性剂、氯化钠、聚二甲基硅氧烷醇、聚二甲基硅氧烷、卡波姆、水解丝胶蛋白、齿缘墨角藻提取物、泡叶藻提取物、刺海门冬提取物、山梨醇、香精、氨端聚二甲基硅氧烷、瓜尔胶羟丙基三甲基氯化铵、氢氧化钠、甲基氯异噻唑啉酮、甲基异噻唑啉酮、苯氧乙醇、EDTA四钠、柠檬酸。
2.一种儿童洗发露，其特征在于，由下述重量份的原料制备而成：月桂醇聚醚硫酸酯钠45-55份、乙二醇二硬脂酸15-25份、椰油酰胺MEA 35-45份、甜菜碱类表面活性剂45-55份、氯化钠1-10份、聚二甲基硅氧烷醇1-10份、聚二甲基硅氧烷1-10份、卡波姆5-15份、水解丝胶蛋白15-25份、齿缘墨角藻提取物1-10份、泡叶藻提取物1-10份、刺海门冬提取物1-10份、山梨醇5-15份、氨端聚二甲基硅氧烷1-10份、瓜尔胶羟丙基三甲基氯化铵5-15份、氢氧化钠1-10份、甲基氯异噻唑啉酮0.1-1份、甲基异噻唑啉酮0.1-1份、苯氧乙醇1-10份、EDTA四钠1-10份、柠檬酸1-10份、香精0.1-1份、水700-900份。
3.如权利要求1或2所述的儿童洗发露，其特征在于：所述的甜菜碱类表面活性剂为椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱中一种或多种的混合物。
4.如权利要求3所述的儿童洗发露，其特征在于：所述的甜菜碱类表面活性剂由椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱混合而成，所述椰油酰胺丙基甜菜碱、3-磺丙基十六烷基二甲甜菜碱、油酰胺丙基甜菜碱的质量比为(1-3)：(1-3)：(1-3)。
5.如权利要求1-4中任一项所述的儿童洗发露的制备方法，其特征在于，包括以下步骤：
将水加热至65-85℃，搅拌条件下依次加入月桂醇聚醚硫酸酯钠、乙二醇二硬脂酸、椰油酰胺MEA、甜菜碱类表面活性剂、聚二甲基硅氧烷醇、聚二甲基硅氧烷、卡波姆、氨端聚二甲基硅氧烷、瓜尔胶羟丙基三甲基氯化铵搅拌混合均匀，降温至45-55℃，再依次加入山梨醇、香精、甲基氯异噻唑啉酮、甲基异噻唑啉酮、苯氧乙醇、EDTA四钠、柠檬酸、氢氧化钠、氯化钠、水解丝胶蛋白、齿缘墨角藻提取物、泡叶藻提取物、刺海门冬提取物搅拌混合均匀即得。
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107669552A (zh) * | 2017-10-31 | 2018-02-09 | 思拓科（上海）生物科技股份有限公司 | 有机婴儿洗发露 |
| CN107822975A (zh) * | 2017-11-29 | 2018-03-23 | 桂林华诺威生物科技有限公司 | 一种草本胶原蛋白洗发水 |
| CN107913230A (zh) * | 2017-11-27 | 2018-04-17 | 曾万祥 | 一种姜汁蛋白养护洗发露 |
| CN108125804A (zh) * | 2018-01-29 | 2018-06-08 | 南阳师范学院 | 一种抑菌清爽型洗头膏及其制备方法 |
| CN115813819A (zh) * | 2022-12-03 | 2023-03-21 | 福建省梦娇兰日用化学品有限公司 | 一种不含硅油的儿童洗发露及其制备方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103720637A (zh) * | 2014-01-22 | 2014-04-16 | 云南龙润茶科技有限公司 | 一种天然植物洗发水和护发素及其制备方法 |
-
2016
- 2016-08-30 CN CN201610766224.2A patent/CN106265277B/zh not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103720637A (zh) * | 2014-01-22 | 2014-04-16 | 云南龙润茶科技有限公司 | 一种天然植物洗发水和护发素及其制备方法 |
Non-Patent Citations (2)
| Title |
|---|
| 如新: "《http://www.cosdna.com/chs/cosmetic_02ed243054.html》", 18 July 2016 * |
| 王建新: "《化妆品植物原料大全》", 30 June 2012 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107669552A (zh) * | 2017-10-31 | 2018-02-09 | 思拓科（上海）生物科技股份有限公司 | 有机婴儿洗发露 |
| CN107913230A (zh) * | 2017-11-27 | 2018-04-17 | 曾万祥 | 一种姜汁蛋白养护洗发露 |
| CN107822975A (zh) * | 2017-11-29 | 2018-03-23 | 桂林华诺威生物科技有限公司 | 一种草本胶原蛋白洗发水 |
| CN108125804A (zh) * | 2018-01-29 | 2018-06-08 | 南阳师范学院 | 一种抑菌清爽型洗头膏及其制备方法 |
| CN115813819A (zh) * | 2022-12-03 | 2023-03-21 | 福建省梦娇兰日用化学品有限公司 | 一种不含硅油的儿童洗发露及其制备方法 |
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