CN106138974A - A kind of pharmaceutical composition improving Qi deficiency physique and a kind of medicine brick and preparation method thereof - Google Patents
A kind of pharmaceutical composition improving Qi deficiency physique and a kind of medicine brick and preparation method thereof Download PDFInfo
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- CN106138974A CN106138974A CN201610757783.7A CN201610757783A CN106138974A CN 106138974 A CN106138974 A CN 106138974A CN 201610757783 A CN201610757783 A CN 201610757783A CN 106138974 A CN106138974 A CN 106138974A
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- radix
- parts
- rhizoma
- fructus
- concentrated solution
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Abstract
The invention provides a kind of pharmaceutical composition improving Qi deficiency physique, described compositions includes following components by weight: Radix Codonopsis 80 120 parts, 100 140 parts of Poria, the Rhizoma Atractylodis Macrocephalae 180 220 parts, Radix Glycyrrhizae Preparata 20 40 parts, the Radix Astragali 100 140 parts, Rhizoma Cimicifugae 50 70 parts, Radix Bupleuri 50 70 parts, Radix Angelicae Sinensis 80 120 parts, Fructus Aurantii Immaturus 40 60 parts, Pericarpium Citri Reticulatae 60 100 parts, Semen Lablab Album 50 70 parts, Semen Coicis 100 140 parts, Rhizoma dioscoreae 130 170 parts, Semen Nelumbinis 50 70 parts, Fructus Amomi 50 70 parts, 10 30 parts of the Radix Rehmanniae, Fructus Corni 20 40 parts, Rhizoma Alismatis 20 40 parts, Cortex Moutan 50 70 parts, Ramulus Cinnamomi 60 100 parts, Radix Aconiti Lateralis Preparata 5 15 parts, Herb Gynostemmae Pentaphylli 20 40 parts.Present invention also offers and use medicine brick of preparing of described compositions and preparation method thereof.
Description
Technical field
The present invention relates to the field of Chinese medicines, in particular to a kind of pharmaceutical composition improving Qi deficiency physique and a kind of medicine
Brick and preparation method thereof.
Background technology
For the people of Qi deficiency physique, the many titles of ancients " gas is weak ", " weakness of QI ", " people of the deficiency of vital energy ", " the Ling Shu Miraculous Pivot or Divine Axis longevity dies young hard and soft " cloud:
" it is hard crisp that shape has emergency, gas to have prosperity and decline, bone to have size, meat to have, and skin has thickness ... shape fill and small pulse with weak person's weakness of QI.”
Popular saying Qi deficiency physique precisely due to the QI-insufficiency of the whole body, function state low based on breath is lowly
Want the constitution status of feature.
Bright ZHANG Jie bin " Jing Yue's complete work miscellaneous card plan " cloud: " the how fertile anti-many deficiency of vital energys of people？The body of lid people, bone is monarch
Also ... and meat is with blood one-tenth, total the moon class that belongs to, therefore fertile people has the card of the deficiency of vital energy more." clear stone longevity Chinese bush cherry " curing former " says: " and be intended to examine its people it
Disease, must first distinguish the makings negative and positive of its people.The matter in Jinsui River, its people is fertile white, belongs to the deficiency of vital energy more." Qi deficiency physique sum up get up to have following 5
Feature.
Body characteristics: muscle is soft.
Psychological peculiarity: introverted, emotional instability, timidity do not like risk.
Common manifestation: major event, lazy speech of usually breathing hard, language is low timid, lassitude, and limbs are the most tired, easily perspire, light red tongue
There is indentation on tender, limit red, fat, and pulse condition void is delayed.Secondary item, shallow complexion or light white, the few god of sight, tastelessness, the few China of pure color, hair is not
Pool, dizzy, forgetful, stool is normal, though or constipation but do not tie hard, or it is shapeless to defecate, and the most still feels to the greatest extent, and urine is normal or partially
Many.
Adaptive capacity to environment to external world: do not tolerate cold-evil, ailment said due to cold or exposure, pathogenic summer-heat.
Morbidity tendency: usually having a delicate constitution, instability of surface is easily caught a cold；Or resistance against diseases is weak after being ill, easy protracted course of disease；Easily
Suffer from the disease such as visceroptosis, asthenia.
Treat the deficiency of vital energy, many employing herbal fomentation therapies by topical agent, utilize hot towel, hot water bag or there is heating
The therapeutic equipments of effect, by middle drug application at people's body surface, by the dual function of medicine Yu hot compress, alleviates, treats cold body constitution.
Herbal fomentation therapy is exactly the physiological property utilizing skin, makes medicine be turned by skin surface absorption, stratum corneum penetration and corium
Transport and play pharmacodynamics effect into blood circulation.Herbal fomentation has concentrated traditional Chinese medical science medication, thermotherapy, tcm herbal ion osmotic therapeutic therapy
Deng several functions, melt temperature, humidity, drug level in one, due to illness treat, medicine suit the medicine to the illness, can effectively treat multiple disease.Directly
Connect and Chinese medicine is heated, eliminate traditional that needs and first Chinese medicine decocting is cooked into liquid cumbersome process, by by the most not
Disconnected medicine of a warm nature molecule directly acts on human body, expansion blood vessel locally and systemically in the way of convection current and infiltration, promotes body surface group
The blood circulation knitted, improves the Absorption of skin, promotes a large amount of secretions of sweat gland, accelerates the metabolism of skin；Simultaneously by
In fomentation medicine effusion Chinese medicine particle (for molecule or ion) act on body surface directly produce acaricide, parasite killing, sterilization, antiinflammatory,
Antipruritic, control pain etc. effect, or transdermal absorption human body by excite histiocyte receptor Biochemical processes play medication make
With, and then eliminate focus.
But, the herbal fomentation therapy in correlation technique, owing to Chinese medicine needs and the dermal contact of patient, but also need
Medical personnel or patient hand-held towel, hot water bag or there is the therapeutic equipments of heat effect, to the position being covered with Chinese medicine
Heating, so, it is not easy to medical personnel or patient's operation.It is therefore desirable to have novel hot compress therapy solves the problems referred to above.
Reporting in prior art and use health-preserving heated brick bed as medical apparatus and instruments, in heated kang, the medicine group of medicine brick is made in heating
Compound, when being administered in this way, medicine brick meeting releasing Chinese medicine particle (for molecule or ion) after heating, thus inhale through transdermal
Take in human body, excite the effect of the Biochemical processes volatilization medication of histiocyte receptor, and then reach to treat affected part
Purpose.This way it is not necessary to the affected part of patient is carried out by medical personnel or the hand-held firing equipment of patient.
But, add the mode difference of medicine of a warm nature brick administration very owing to being conventionally used for herbal fomentation therapy with employing health-preserving heated brick bed
Greatly, in order to adapt to different administering modes, need one can prepare patent medicine brick, and be well adapted for heating this administration of administration
The compositions of mode, it the most also needs to have good drug effect concurrently.
In view of this, the present invention is proposed.
Summary of the invention
The first object of the present invention is to provide a kind of pharmaceutical composition improving Qi deficiency physique, described pharmaceutical composition
Can effectively improve Qi deficiency physique, and adapt to the administering mode of heating topical administration especially；
The second object of the present invention is to provide a kind of medicine brick, and described medicine brick is mixed system by described pharmaceutical composition with loess
Standby, it is possible to discharge pharmaceutically active substance by heating well, reach therapeutic effect；
The third object of the present invention is to provide the preparation method of described medicine brick, and described method process is clear and definite, it is easy to
Control, favorable reproducibility.
In order to realize the above-mentioned purpose of the present invention, spy by the following technical solutions:
One aspect of the present invention relates to a kind of pharmaceutical composition improving Qi deficiency physique, and described compositions includes by weight
The following components of part meter:
Radix Codonopsis 80-120 part, Poria 100-140 part, Rhizoma Atractylodis Macrocephalae 180-220 part, Radix Glycyrrhizae Preparata 20-40 part, Radix Astragali 100-140 part,
Rhizoma Cimicifugae 50-70 part, Radix Bupleuri 50-70 part, Radix Angelicae Sinensis 80-120 part, Fructus Aurantii Immaturus 40-60 part, Pericarpium Citri Reticulatae 60-100 part, Semen Lablab Album 50-70 part,
Semen Coicis 100-140 part, Rhizoma dioscoreae 130-170 part, Semen Nelumbinis 50-70 part, Fructus Amomi 50-70 part, Radix Rehmanniae 10-30 part, Fructus Corni
20-40 part, Rhizoma Alismatis 20-40 part, Cortex Moutan 50-70 part, Ramulus Cinnamomi 60-100 part, Radix Aconiti Lateralis Preparata 5-15 part, Herb Gynostemmae Pentaphylli 20-40 part.
Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata have a collaborative compatibility left side forever, and Radix Ginseng is monarch, sweet temperature QI invigorating, strengthening the spleen and nourishing the stomach.Minister with
The bitter using warming therapy Rhizoma Atractylodis Macrocephalae, the spleen strengthening and damp drying, strengthen QI invigorating and help the power of fortune；Assistant is with sweet light Poria, spleen invigorating eliminating dampness by diuresis, and Siberian cocklebur art matches, then spleen invigorating is dispelled
Wet merit benefit writes.Make with Radix Glycyrrhizae Preparata, QI invigorating and in, coordinating the actions of various ingredients in a prescription.Four medicine compatibilities, play the merit of replenishing QI to invigorate the spleen altogether.
The Radix Astragali, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata, Rhizoma Cimicifugae, Radix Bupleuri, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae have collaborative compatibility effect." name hospital at all times
Opinion " volume 1 record, " all taste one are empty, and lung qi the most absolutely, therefore closes pancreas reason with Radix Astragali sheath hair, does not make spontaneous perspiration；Insufficiency of primordial QI, lazy speech
Asthma, Radix Ginseng is to mend it；The sweet relieving restlessness with eliminating heart-fire of Radix Glycyrrhizae Preparata, tonifying the spleen and stomach and angry.This three taste, the panacea of heat clearing away and restlessness relieving is also.
The assistant Rhizoma Atractylodis Macrocephalae is with spleen invigorating；Radix Angelicae Sinensis with and blood；Disturbance of QI is in breast, and abnormal ascent-descent between clear YANG and turbid YIN, with Pericarpium Citri Reticulatae to manage it, and to dissipate the stagnant of all sweet medicines；In stomach
Clearing heat in QI system sinks, and with Rhizoma Cimicifugae, the gently thin person of taste of Radix Bupleuri gas, draws more than gastric qi and rises, its one's own department or unit multiple, just can rise floating to go growth
Order.The agent of invigorating middle warmer, the product that must deliver and in from peace；The agent of QI invigorating, relies the product of clearing heat in QI system and gas benefit times, and this medication has the wonderful of mutual reinforcement between
Also.
Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Semen Coicis, Rhizoma Dioscoreae, Semen Nelumbinis, Fructus Amomi, Radix Platycodonis, Radix Glycyrrhizae Preparata, Fructus Jujubae have association
Same compatibility effect, it cures mainly deficiency-weakness of spleen-QI, endogenous dampness, and disease sees distension and fullness in the abdomen, anorexia, diarrhea, limbs fatigue, shape
Body is become thin, shallow complexion, white and greasy fur, and pulse condition does not carefully delay person.Also controlling children's's infantile spleen malnutrition, shallow complexion, wan and sallow looking, hair is withered,
Lethargy, anorexia, doss peaceful, or edema due to deficiency of the spleen, or insufficiency of the spleen dai channel be solid, leukorrhagia, continuous constantly, such as tears such as
Saliva person.
Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Fructus Corni, Poria, Rhizoma Alismatis, Cortex Moutan and Ramulus Cinnamomi, Radix Aconiti Lateralis Preparata etc. eight taste Chinese medicine there is compatibility effect, use
In the disease caused by treatment insufficiency of kidney-YANG, as cold in waist knee joint acid, cough, sexual impotence, premature ejaculation, chronic nephritis, diabetes aldosteronism,
Renal edema, the institute such as hypocorticoidism disease, hypothyroidism, chronic bronchial asthma, climacteric syndrome
Performance lumbago lower limb is soft, health is afraid of cold, the disease such as lower abdomen contracture, clear urine in large amounts, light red tongue are fat, thready pulse without strength.
Preferably, described compositions includes following components by weight:
Radix Codonopsis 90-110 part, Poria 110-130 part, Rhizoma Atractylodis Macrocephalae 190-210 part, Radix Glycyrrhizae Preparata 25-35 part, Radix Astragali 110-130 part,
Rhizoma Cimicifugae 55-65 part, Radix Bupleuri 55-65 part, Radix Angelicae Sinensis 90-110 part, Fructus Aurantii Immaturus 45-55 part, Pericarpium Citri Reticulatae 70-90 part, Semen Lablab Album 55-65 part, the heart of a lotus seed
Semen Coicis 110-130 part, Rhizoma dioscoreae 140-160 part, Semen Nelumbinis 55-65 part, Fructus Amomi 55-65 part, Radix Rehmanniae 15-25 part, Fructus Corni 25-
35 parts, Rhizoma Alismatis 25-35 part, Cortex Moutan 55-65 part, Ramulus Cinnamomi 90-110 part, Radix Aconiti Lateralis Preparata 8-12 part, Herb Gynostemmae Pentaphylli 25-35 part.
Preferably, described compositions also includes accessory drugs, it is preferable that described accessory drugs includes following components by weight:
Radix Et Caulis Acanthopanacis Senticosi 20-40 part, Radix Rhodiolae 50-70 part, Fructus Hippophae 10-30 part, Radix Ranunculi Ternati 20-40 part, Oletum Trogopterori 20-40 part,
Flos Campsis 40-60 part, Herba Artemisiae Anomalae 60-100 part, Fructus Aurantii, the Radix Aucklandiae, Fructus Citri, Semen Canavaliae.
Radix Et Caulis Acanthopanacis Senticosi, sees Shennong's Herbal, is classified as top grade.Top grade be refer to nontoxic, for a long time clothes can make light of one's life by commiting suicide, life lengthening and
Harmless.Radix Et Caulis Acanthopanacis Senticosi is the most i.e. considered to have and adds essence and mend marrow and the good medicine of anti-aging effects.Trade name Radix Acanthopanacis Senticosi, former main product in
Mountain area, Heilongjiang Province, local popular name is practised and is claimed " tiger is hasty and careless ", is then referred to as the smooth slender acanthopanax of shrimp in Japan, and is also called western Berli in the former Soviet Union
Sub-Radix Ginseng.Ming Dynasty's Li Shizhen (1518-1593 A.D.) Compendium of Material Medica claims Radix Et Caulis Acanthopanacis Senticosi, good with the five leaf persons of accompanying each other, therefore named slender acanthopanax, has another name called five flowers.Slender acanthopanax controls wind
Wet, strengthening bone and muscle, its merit is good deeply, and Ning get Yi, slender acanthopanax, need not expire car by gold and jade, and " wine made in article, can become its taste, with Jin Maicao, no again
Yan Qigui " say, slender acanthopanax has been cooked the highest praise.
Herb Gynostemmae Pentaphylli, for the herb of cucurbitaceous plant Herb Gynostemmae Pentaphylli, 1986, State Scientific and Technological Commission was in Spark Program, strand
Indigo plant is classified as the first place of " rare Chinese medicine " leaved for development, and on March 5th, 2002, health ministry was listed in health product list.This
Plant and be used as medicine, have effect of eliminating inflammation and expelling toxin, eliminating phlegm and stopping cough.Arrange in pairs or groups to boil water with Herb Gynostemmae Pentaphylli and Ganoderma or brew up, can treat hypertension,
Hyperlipidemia, hyperglycemia, the disease such as fatty liver.There are protecting liver and detoxication, effect of lowering blood pressure and blood fat blood glucose.
Radix Rhodiolae, is grown in the high and cold pollution-free area of height above sea level 1,800 2500 meters, and its growing environment is severe, thus has very
Strong vitality and special adaptability.Can make medicinal, it is possible to QI invigorating lung heat clearing, Fructus Alpiniae Oxyphyllae is nourished heart, and is to act on Chinese medicine widely simply.
Also there is the biggest cosmetic result, skin care item can be made, it is possible to be edible.Nature and flavor: cold, sweet, puckery.Gui Jing: lung meridian.Function: have QI invigorating clear
Lung, Fructus Alpiniae Oxyphyllae nourish heart, effect of hemostasis with astringents, dissipating blood stasis for subsidence of swelling.Cure mainly deficiency of vital energy and physically weak, after being ill fear of cold, shortness of breath and fatigue, cough due to lung-heat,
Spitting of blood, leucorrhea diarrhoea, traumatic injury etc..
Fructus Hippophae, sea buckthorn fruit is used as medicine and has effect of relieving cough and resolving phlegm, invigorating the stomach and promoting digestion, promoting blood circulation to remove blood stasis.Modern medicine study, husky
Spine can reduce cholesterol, and allevating angina pectoris shows effect, and also prevents and treats the effect of coronary atherosclerotic heart disease.For coughing
Abundant expectoration, dyspepsia, abdominal pain due to retention of food, fall and flutter congestive edema, blood stasis amenorrhea.
Radix Ranunculi Ternati, modern pharmacology and clinical research show, Radix Ranunculi Ternati and preparation thereof are to pulmonary tuberculosis, lymphoid tuberculosis and multiple cancer
Disease and lymphoma are effective in cure.Its sweet, acrid, warm.Enter liver, lung two warp, can dissipating phlegm and resolving masses, removing toxic substances and promoting subsidence of swelling, treat Drug resistant pulmonary tubeculosis,
The patient of the most resistance to isoniazid, rifampicin and streptomycin.Cure mainly pulmonary tuberculosis, malaria, scrofula sucutaneous nodule, furuncle, worm venom, partially
Headache, malaria, toothache.Tuberculous lymphadenitis, lymphadenitis, pharyngolaryngitis.
Oletum Trogopterori, Oletum Trogopterori is the dry feces of trogopterus xanthipes Milne-Edwards, can be used for blood-stasis internal-depression, escape of blood from meridian hemorrhage, such as woman
Female's metrorrhagia through many, color purple polylith, stabbing pain of the lower abdomen.Both can single fry ground into powder, heat wine takes, again can with other drug with the use of.
Oletum Trogopterori is blood-activating and stasis-removing, and Compendium of Material Medica is said: " [promoting blood circulation to remove blood stasis, parch to black stops blooding Oletum Trogopterori.Have a pain for trusted subordinate's congestion,
Dysmenorrhea, blood stasis amenorrhea, curing postpartum bleeding is suffered from abdominal pain；Parch to black controls metrostaxis；Traumatic injury, Serpentis, insect bite wound are controlled in external.
Flos Campsis, " Book of Songs " as far back as the The Spring and Autumn Period of reaching the clouds is inner the most on the books, and people were referred to as mound sweet potato at that time, " China of sweet potato,
It is expensive for rue " reaching the clouds exactly of saying.The name of Flos Campsis is first appeared in Tang Materia Medica, and this book is said under " purple luxuriant " item: " this is Flos Campsis
Also, and stem, leaf tool use.Promoting the circulation of blood blood stasis removing, cooling blood, expelling wind.For amenorrhea, puerperal swelling of the breast, rubella is rubescent, skin pruritus, acne.
Herba Artemisiae Anomalae, bitter, temperature, GUIXIN, liver, spleen channel.Removing blood stasis stimulates the menstrual flow, healing up sore and subduing swelling.Control amenorrhea lump in the abdomen, chest and abdomen swelling and pain, puerperal
Blood stasis, traumatic injury, incised wound is hemorrhage, and carbuncle poison swells.It has hemostasis of curing the wound, and removing blood stasis stimulates the menstrual flow, promoting digestion and removing stagnation, the merit of appetizing of being amusing
Effect.It can be used for acute icterohepatitis, toothache, chronic tracheitis, stomatitis, pharyngolaryngitis, tonsillitis, nephritis, malaria；Outward
With controlling eye conjunctivitis, otitis media, skin infection, eczema, traumatic hemorrhage.
Another aspect of the present invention relates to improve the medicine brick of Qi deficiency physique, and described medicine brick is mainly by described medicine group
Compound and loess are made.
Loess can organically combine with Chinese herbal medicine and various mineral, containing useful to the person in the loess of selection
30 various trace elements such as boron, iodine, zinc, selenium, copper, magnesium, calcium, play defying age, anticancer change, the stability of maintenance cell membrane, carry
High immunologic function, then with the combination of Chinese herbal medicine and various mineral after, the health maintenance effect of product is greatly improved.
Preferably, the weight ratio of described loess and described pharmaceutical composition is: (0.5-2): 1.
Another aspect of the present invention relates to the preparation method of described medicine brick, said method comprising the steps of:
1) Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata boiling are obtained decoction of four noble drugs；By the Radix Astragali, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata,
Rhizoma Cimicifugae, Radix Bupleuri, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae boiling obtain BUZHONG YIQI TANG；
2) described decoction of four noble drugs and BUZHONG YIQI TANG are mixed and concentrating under reduced pressure obtains middle concentrated solution；
3) continue to concentrate by described middle concentrated solution, obtain final concentrated solution；
4) by Fructus Aurantii Immaturus, Semen Lablab Album, Semen Coicis, Rhizoma dioscoreae, Semen Nelumbinis, Fructus Corni, Fructus Amomi, the Radix Rehmanniae, Rhizoma Alismatis, Cortex Moutan, Ramulus Cinnamomi,
Radix Aconiti Lateralis Preparata, Herb Gynostemmae Pentaphylli are pulverized and mixed after being respectively prepared decoction pieces, and are mixed to prepare medicine brick mixture with described final concentrated solution；
5) by described mixture punch forming drying and shaping, finished medicines brick is prepared.
By by common for some specific components decocting, the effect of its collaborative compatibility can be given full play to, be formed and have well
The Synergistic between each component can be given full play to after the decoction of drug effect, the ground product of itself and other component and loess mixing make
With, and obtain being particularly suitable for the medicine brick of the heating administering mode of health-preserving heated brick bed.
Preferably, the step 4 of described method) in, by Radix Et Caulis Acanthopanacis Senticosi, Radix Rhodiolae, Fructus Hippophae, Radix Ranunculi Ternati, Oletum Trogopterori, Flos Campsis,
Herba Artemisiae Anomalae, Fructus Aurantii, the Radix Aucklandiae, Fructus Citri, Semen Canavaliae are pulverized after being also respectively prepared decoction pieces, mix with the decoction pieces ground product of other components, and
Together it is mixed to prepare mixture with described final concentrated solution.
Preferably, described middle concentrated solution, the relative density when 50 DEG C is 1.05-1.08g/cm3；Described final concentration
The liquid relative density when 50 DEG C is 1.30-1.35g/cm3。
By decoction is concentrated, can be so that the mixing of its other components with powder in subsequent step.
Preferably, described step 1) in, decocting and carry out twice, the weight every time adding water is to treat decocting herbs gross weight
8-12 times, each decocting time is 50-70min, and after decocting, filtrate crosses 300 mesh sieves every time.
Some components of decocting drug regimen species, can be beneficial to extract the effective ingredient in medical material, and it is had
Evil composition filters with medicinal residues.
Preferably, described step 5) in, the pressing time in punching course is 2-3min, dries temperature and is 40-45 DEG C, excellent
Selection of land, baking duration is 1.5-2.5h.
Compared with prior art, the invention have the benefit that
The pharmaceutical composition of the present invention can improve Qi deficiency physique effectively, and adapts to the administration of heating topical administration especially
Mode；
The medicine brick of the present invention is mixed with loess by described pharmaceutical composition, it is possible to well by heating release drug
Active substances, reaches therapeutic effect；
The preparation method that the present invention provides, process is clear and definite, it is easy to control, favorable reproducibility.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but those skilled in the art will
Understanding, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the present invention.In embodiment unreceipted specifically
Condition person, the condition advised according to normal condition or manufacturer is carried out.Agents useful for same or instrument unreceipted production firm person, be
Can be by the commercially available conventional products bought and obtain.
Embodiment 1
Prepare the medicine brick for treating yin-deficiency constitution in accordance with the following steps
1. prepare following raw material by weight and the loess of medical material gross weight 1 times amount
Radix Codonopsis 80 parts, 100 parts of Poria, the Rhizoma Atractylodis Macrocephalae 180 parts, Radix Glycyrrhizae Preparata 20 parts, the Radix Astragali 100 parts, Rhizoma Cimicifugae 50 parts, Radix Bupleuri 50 parts,
Radix Angelicae Sinensis 80 parts, Fructus Aurantii Immaturus 40 parts, Pericarpium Citri Reticulatae 60 parts, Semen Lablab Album 50 parts, Semen Coicis 100 parts, Rhizoma dioscoreae 130 parts, Semen Nelumbinis 50 parts, Fructus Amomi
50 parts, 10 parts of the Radix Rehmanniae, Fructus Corni 20 parts, Rhizoma Alismatis 20 parts, Cortex Moutan 50 parts, Ramulus Cinnamomi 60 parts, Radix Aconiti Lateralis Preparata 5 parts, Herb Gynostemmae Pentaphylli 20 parts.
2. Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata boiling are obtained decoction of four noble drugs；By the Radix Astragali, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata,
Rhizoma Cimicifugae, Radix Bupleuri, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae boiling obtain BUZHONG YIQI TANG；Decoction is carried out twice, adds the weight of water for waiting to decoct every time
Decocting medicinal herbs 8 times of material gross weight, each decocting time is 50min, and after decocting, filtrate crosses 300 mesh sieves every time.
3. described decoction of four noble drugs and BUZHONG YIQI TANG are mixed and concentrating under reduced pressure obtain concentrated solution in the middle of described in middle concentrated solution,
Relative density when 50 DEG C is 1.05g/cm3；
4. continuing to concentrate in described middle concentrated solution is placed in jacketed pan, obtain final concentrated solution, described final concentrated solution exists
Relative density when 50 DEG C is 1.30g/cm3；
5. by Fructus Aurantii Immaturus, Semen Lablab Album, Semen Coicis, Rhizoma dioscoreae, Semen Nelumbinis, Fructus Corni, Fructus Amomi, the Radix Rehmanniae, Rhizoma Alismatis, Cortex Moutan, Ramulus Cinnamomi,
Radix Aconiti Lateralis Preparata, Herb Gynostemmae Pentaphylli are pulverized and mixed after being respectively prepared decoction pieces, and are mixed to prepare medicine brick mixture with described final concentrated solution；
6., by described mixture punch forming drying and shaping, prepare finished medicines brick, wherein, during pressurization in punching course
Between be 2min, dry temperature be 40 DEG C, baking duration is 1.5h.
Embodiment 2
Prepare the medicine brick for treating yin-deficiency constitution in accordance with the following steps
1. prepare following raw material by weight and the loess of medical material gross weight 0.5 times amount
Radix Codonopsis 120 parts, 140 parts of Poria, the Rhizoma Atractylodis Macrocephalae 220 parts, Radix Glycyrrhizae Preparata 40 parts, the Radix Astragali 140 parts, Rhizoma Cimicifugae 70 parts, Radix Bupleuri 70 parts,
Radix Angelicae Sinensis 120 parts, Fructus Aurantii Immaturus 60 parts, Pericarpium Citri Reticulatae 100 parts, Semen Lablab Album 70 parts, Semen Coicis 140 parts, Rhizoma dioscoreae 170 parts, Semen Nelumbinis 70 parts, sand
Core 70 parts, 30 parts of the Radix Rehmanniae, Fructus Corni 40 parts, Rhizoma Alismatis 40 parts, Cortex Moutan 70 parts, Ramulus Cinnamomi 100 parts, Radix Aconiti Lateralis Preparata 15 parts, Herb Gynostemmae Pentaphylli 40 parts.
2. Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata boiling are obtained decoction of four noble drugs；By the Radix Astragali, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata,
Rhizoma Cimicifugae, Radix Bupleuri, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae boiling obtain BUZHONG YIQI TANG；Decoction is carried out twice, adds the weight of water for waiting to decoct every time
Decocting medicinal herbs 12 times of material gross weight, each decocting time is 70min, and after decocting, filtrate crosses 300 mesh sieves every time.
3. described decoction of four noble drugs and BUZHONG YIQI TANG are mixed and concentrating under reduced pressure obtain concentrated solution in the middle of described in middle concentrated solution,
Relative density when 50 DEG C is 1.08g/cm3；
4. continuing to concentrate in described middle concentrated solution is placed in jacketed pan, obtain final concentrated solution, described final concentrated solution exists
Relative density when 50 DEG C is 1.35g/cm3；
5. by Fructus Aurantii Immaturus, Semen Lablab Album, Semen Coicis, Rhizoma dioscoreae, Semen Nelumbinis, Fructus Corni, Fructus Amomi, the Radix Rehmanniae, Rhizoma Alismatis, Cortex Moutan, Ramulus Cinnamomi,
Radix Aconiti Lateralis Preparata, Herb Gynostemmae Pentaphylli are pulverized and mixed after being respectively prepared decoction pieces, and are mixed to prepare medicine brick mixture with described final concentrated solution；
6., by described mixture punch forming drying and shaping, prepare finished medicines brick, wherein, during pressurization in punching course
Between be 3min, dry temperature be 45 DEG C, baking duration is 2.5h.
Embodiment 3
Prepare the medicine brick for treating yin-deficiency constitution in accordance with the following steps
1. prepare following raw material by weight and the loess of medical material gross weight 2 times amount
Radix Codonopsis 90 parts, 110 parts of Poria, the Rhizoma Atractylodis Macrocephalae 190 parts, Radix Glycyrrhizae Preparata 25 parts, the Radix Astragali 110 parts, Rhizoma Cimicifugae 55 parts, Radix Bupleuri 55 parts,
Radix Angelicae Sinensis 90 parts, Fructus Aurantii Immaturus 45 parts, Pericarpium Citri Reticulatae 70 parts, Semen Lablab Album 55 parts, Semen Coicis 110 parts, Rhizoma dioscoreae 140 parts, Semen Nelumbinis 55 parts, Fructus Amomi
55 parts, 1525 parts of the Radix Rehmanniae, Fructus Corni 25 parts, Rhizoma Alismatis 25 parts, Cortex Moutan 55 parts, Ramulus Cinnamomi 90 parts, Radix Aconiti Lateralis Preparata 8 parts, Herb Gynostemmae Pentaphylli 25 parts, thorn five
Add 20 parts, Radix Rhodiolae 50 parts, Fructus Hippophae 10 parts, Radix Ranunculi Ternati 20 parts, Oletum Trogopterori 2040 parts, Flos Campsis 40 parts, Herba Artemisiae Anomalae 60 parts, trifoliate orange
Shell, the Radix Aucklandiae, Fructus Citri, Semen Canavaliae.
2. Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata boiling are obtained decoction of four noble drugs；By the Radix Astragali, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata,
Rhizoma Cimicifugae, Radix Bupleuri, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae boiling obtain BUZHONG YIQI TANG；Decoction is carried out twice, adds the weight of water for waiting to decoct every time
Decocting medicinal herbs 12 times of material gross weight, each decocting time is 70min, and after decocting, filtrate crosses 300 mesh sieves every time.
3. described decoction of four noble drugs and BUZHONG YIQI TANG are mixed and concentrating under reduced pressure obtain concentrated solution in the middle of described in middle concentrated solution,
Relative density when 50 DEG C is 1.08g/cm3；
4. continuing to concentrate in described middle concentrated solution is placed in jacketed pan, obtain final concentrated solution, described final concentrated solution exists
Relative density when 50 DEG C is 1.35g/cm3；
5. by Fructus Aurantii Immaturus, Semen Lablab Album, Semen Coicis, Rhizoma dioscoreae, Semen Nelumbinis, Fructus Corni, Fructus Amomi, the Radix Rehmanniae, Rhizoma Alismatis, Cortex Moutan, Ramulus Cinnamomi,
Radix Aconiti Lateralis Preparata, Herb Gynostemmae Pentaphylli, Radix Et Caulis Acanthopanacis Senticosi, Radix Rhodiolae, Fructus Hippophae, Radix Ranunculi Ternati, Oletum Trogopterori, Flos Campsis, Herba Artemisiae Anomalae, Fructus Aurantii, the Radix Aucklandiae, Fructus Citri, cutter
Bean is respectively prepared decoction pieces, after pulverizing and mixing, is mixed to prepare mixture with described final concentrated solution；
6., by described mixture punch forming drying and shaping, prepare finished medicines brick, wherein, during pressurization in punching course
Between be 3min, dry temperature be 45 DEG C, baking duration is 2.5h.
Embodiment 4
Prepare the medicine brick for treating yin-deficiency constitution in accordance with the following steps
1. prepare following raw material by weight and the loess of medical material gross weight 1.5 times amount
Radix Codonopsis 110 parts, 130 parts of Poria, the Rhizoma Atractylodis Macrocephalae 210 parts, Radix Glycyrrhizae Preparata 35 parts, the Radix Astragali 130 parts, Rhizoma Cimicifugae 65 parts, Radix Bupleuri 65 parts,
Radix Angelicae Sinensis 110 parts, Fructus Aurantii Immaturus 55 parts, Pericarpium Citri Reticulatae 90 parts, Semen Lablab Album 65 parts, Semen Coicis 130 parts, Rhizoma dioscoreae 160 parts, Semen Nelumbinis 65 parts, sand
Core 65 parts, 25 parts of the Radix Rehmanniae, Fructus Corni 35 parts, Rhizoma Alismatis 35 parts, Cortex Moutan 65 parts, Ramulus Cinnamomi 110 parts, Radix Aconiti Lateralis Preparata 12 parts, Herb Gynostemmae Pentaphylli 35 parts, thorn
Slender acanthopanax 40 parts, Radix Rhodiolae 70 parts, Fructus Hippophae 30 parts, Radix Ranunculi Ternati 40 parts, Oletum Trogopterori 40 parts, Flos Campsis 60 parts, Herba Artemisiae Anomalae 100 parts, trifoliate orange
Shell, the Radix Aucklandiae, Fructus Citri, Semen Canavaliae.
2. Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata boiling are obtained decoction of four noble drugs；By the Radix Astragali, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata,
Rhizoma Cimicifugae, Radix Bupleuri, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae boiling obtain BUZHONG YIQI TANG；Decoction is carried out twice, adds the weight of water for waiting to decoct every time
Decocting medicinal herbs 10 times of material gross weight, each decocting time is 65min, and after decocting, filtrate crosses 300 mesh sieves every time.
3. described decoction of four noble drugs and BUZHONG YIQI TANG are mixed and concentrating under reduced pressure obtain concentrated solution in the middle of described in middle concentrated solution,
Relative density when 50 DEG C is 1.07g/cm3；
4. continuing to concentrate in described middle concentrated solution is placed in jacketed pan, obtain final concentrated solution, described final concentrated solution exists
Relative density when 50 DEG C is 1.33g/cm3；
5. by Fructus Aurantii Immaturus, Semen Lablab Album, Semen Coicis, Rhizoma dioscoreae, Semen Nelumbinis, Fructus Corni, Fructus Amomi, the Radix Rehmanniae, Rhizoma Alismatis, Cortex Moutan, Ramulus Cinnamomi,
Radix Aconiti Lateralis Preparata, Herb Gynostemmae Pentaphylli, Radix Et Caulis Acanthopanacis Senticosi, Radix Rhodiolae, Fructus Hippophae, Radix Ranunculi Ternati, Oletum Trogopterori, Flos Campsis, Herba Artemisiae Anomalae, Fructus Aurantii, the Radix Aucklandiae, Fructus Citri, cutter
Bean is respectively prepared decoction pieces, after pulverizing and mixing, is mixed to prepare mixture with described final concentrated solution；
6., by described mixture punch forming drying and shaping, prepare finished medicines brick, wherein, during pressurization in punching course
Between be 2min, dry temperature be 42 DEG C, baking duration is 1.5h.
Embodiment 5
Prepare the medicine brick for treating yin-deficiency constitution in accordance with the following steps
1. prepare following raw material by weight and the loess of medical material gross weight 1 times amount
Radix Codonopsis 100 parts, 120 parts of Poria, the Rhizoma Atractylodis Macrocephalae 200 parts, Radix Glycyrrhizae Preparata 30 parts, the Radix Astragali 120 parts, Rhizoma Cimicifugae 60 parts, Radix Bupleuri 60 parts,
Radix Angelicae Sinensis 100 parts, Fructus Aurantii Immaturus 50 parts, Pericarpium Citri Reticulatae 80 parts, Semen Lablab Album 60 parts, Semen Coicis 120 parts, Rhizoma dioscoreae 150 parts, Semen Nelumbinis 60 parts, sand
Core 60 parts, 20 parts of the Radix Rehmanniae, Fructus Corni 30 parts, Rhizoma Alismatis 30 parts, Cortex Moutan 60 parts, Ramulus Cinnamomi 80 parts, Radix Aconiti Lateralis Preparata 10 parts, Herb Gynostemmae Pentaphylli 30 parts, thorn
Slender acanthopanax 30 parts, Radix Rhodiolae 60 parts, Fructus Hippophae 20 parts, Radix Ranunculi Ternati 30 parts, Oletum Trogopterori 30 parts, Flos Campsis 50 parts, Herba Artemisiae Anomalae 80 parts, trifoliate orange
Shell, the Radix Aucklandiae, Fructus Citri, Semen Canavaliae.
2. Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata boiling are obtained decoction of four noble drugs；By the Radix Astragali, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata,
Rhizoma Cimicifugae, Radix Bupleuri, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae boiling obtain BUZHONG YIQI TANG；Decoction is carried out twice, adds the weight of water for waiting to decoct every time
Decocting medicinal herbs 12 times of material gross weight, each decocting time is 70min, and after decocting, filtrate crosses 300 mesh sieves every time.
3. described decoction of four noble drugs and BUZHONG YIQI TANG are mixed and concentrating under reduced pressure obtain concentrated solution in the middle of described in middle concentrated solution,
Relative density when 50 DEG C is 1.06g/cm3；
4. continuing to concentrate in described middle concentrated solution is placed in jacketed pan, obtain final concentrated solution, described final concentrated solution exists
Relative density when 50 DEG C is 1.32g/cm3；
5. by Fructus Aurantii Immaturus, Semen Lablab Album, Semen Coicis, Rhizoma dioscoreae, Semen Nelumbinis, Fructus Corni, Fructus Amomi, the Radix Rehmanniae, Rhizoma Alismatis, Cortex Moutan, Ramulus Cinnamomi,
Radix Aconiti Lateralis Preparata, Herb Gynostemmae Pentaphylli, Radix Et Caulis Acanthopanacis Senticosi, Radix Rhodiolae, Fructus Hippophae, Radix Ranunculi Ternati, Oletum Trogopterori, Flos Campsis, Herba Artemisiae Anomalae, Fructus Aurantii, the Radix Aucklandiae, Fructus Citri, cutter
Bean is respectively prepared decoction pieces, after pulverizing and mixing, is mixed to prepare mixture with described final concentrated solution；
6., by described mixture punch forming drying and shaping, prepare finished medicines brick, wherein, during pressurization in punching course
Between be 3min, dry temperature be 42 DEG C, baking duration is 2h.
Experimental example
Enlisting the volunteer of 500 Qi deficiency physique, be equally divided into 5 groups, group 15 uses the medicine of preparation in embodiment 15 respectively
Brick coordinates health-preserving heated brick bed to carry out Experiment on therapy, after treating two weeks, tests and assesses the deficiency of vital energy situation of its body constitution, and is finally given and controls
The evaluation of therapeutic effect, evaluate be divided into, in, differ from three kinds；Wherein, Qi deficiency physique be improved significantly, deficiency of vital energy symptom is substantially completely
Disappear is chosen as；Qi deficiency physique is effectively improved, in being chosen as of deficiency of vital energy symptom partial disappearance；Qi deficiency physique is substantially without changing
Kind, being chosen as of the nearly no disappearance of symptom that the deficiency of vital energy causes is poor, obtains the volunteer's demographics result such as following table institute of each evaluation
Show.
| Group/effect assessment | Good | In | Difference |
| 1 | 79 | 8 | 13 |
| 2 | 84 | 15 | 1 |
| 3 | 89 | 11 | 0 |
| 4 | 92 | 5 | 3 |
| 5 | 99 | 1 | 0 |
As can be seen from the above table, the medicine brick of the present invention, the medicine brick especially prepared according to preferred ingredient proportioning of the present invention,
Treatment Qi deficiency physique aspect effective percentage is high.
Although illustrate and describing the present invention with specific embodiment, but it will be appreciated that without departing substantially from the present invention's
May be made that in the case of spirit and scope many other change and amendment.It is, therefore, intended that in the following claims
Including all such changes and modifications belonged in the scope of the invention.
Claims (10)
1. the pharmaceutical composition improving Qi deficiency physique, it is characterised in that described compositions includes below by weight
Component:
Radix Codonopsis 80-120 part, Poria 100-140 part, Rhizoma Atractylodis Macrocephalae 180-220 part, Radix Glycyrrhizae Preparata 20-40 part, Radix Astragali 100-140 part, Rhizoma Cimicifugae
50-70 part, Radix Bupleuri 50-70 part, Radix Angelicae Sinensis 80-120 part, Fructus Aurantii Immaturus 40-60 part, Pericarpium Citri Reticulatae 60-100 part, Semen Lablab Album 50-70 part, Semen Coicis
Core 100-140 part, Rhizoma dioscoreae 130-170 part, Semen Nelumbinis 50-70 part, Fructus Amomi 50-70 part, Radix Rehmanniae 10-30 part, Fructus Corni 20-40
Part, Rhizoma Alismatis 20-40 part, Cortex Moutan 50-70 part, Ramulus Cinnamomi 60-100 part, Radix Aconiti Lateralis Preparata 5-15 part, Herb Gynostemmae Pentaphylli 20-40 part.
Pharmaceutical composition the most according to claim 1, it is characterised in that described compositions includes below by weight
Component:
Radix Codonopsis 90-110 part, Poria 110-130 part, Rhizoma Atractylodis Macrocephalae 190-210 part, Radix Glycyrrhizae Preparata 25-35 part, Radix Astragali 110-130 part, Rhizoma Cimicifugae
55-65 part, Radix Bupleuri 55-65 part, Radix Angelicae Sinensis 90-110 part, Fructus Aurantii Immaturus 45-55 part, Pericarpium Citri Reticulatae 70-90 part, Semen Lablab Album 55-65 part, Semen Coicis
110-130 part, Rhizoma dioscoreae 140-160 part, Semen Nelumbinis 55-65 part, Fructus Amomi 55-65 part, Radix Rehmanniae 15-25 part, Fructus Corni 25-35
Part, Rhizoma Alismatis 25-35 part, Cortex Moutan 55-65 part, Ramulus Cinnamomi 90-110 part, Radix Aconiti Lateralis Preparata 8-12 part, Herb Gynostemmae Pentaphylli 25-35 part.
Pharmaceutical composition the most according to claim 1, it is characterised in that it is auxiliary that described compositions also includes by weight
Medicine, it is preferable that described accessory drugs includes following components by weight:
Radix Et Caulis Acanthopanacis Senticosi 20-40 part, Radix Rhodiolae 50-70 part, Fructus Hippophae 10-30 part, Radix Ranunculi Ternati 20-40 part, Oletum Trogopterori 20-40 part, reach the clouds
Flower 40-60 part, Herba Artemisiae Anomalae 60-100 part.
4. the medicine brick being used for improving Qi deficiency physique, it is characterised in that described medicine brick is mainly by any one in claim 1-3
Pharmaceutical composition and loess described in Xiang are made.
Medicine brick the most according to claim 4, it is characterised in that the weight ratio of described loess and described pharmaceutical composition is:
(0.5-2):1。
6. the preparation method of the medicine brick described in claim 4 or 5, it is characterised in that said method comprising the steps of:
1) Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata boiling are obtained decoction of four noble drugs；By the Radix Astragali, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata, Rhizoma Cimicifugae,
Radix Bupleuri, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae boiling obtain BUZHONG YIQI TANG；
2) described decoction of four noble drugs and BUZHONG YIQI TANG are mixed and concentrating under reduced pressure obtains middle concentrated solution；
3) continue to concentrate by described middle concentrated solution, obtain final concentrated solution；
4) by Fructus Aurantii Immaturus, Semen Lablab Album, Semen Coicis, Rhizoma dioscoreae, Semen Nelumbinis, Fructus Corni, Fructus Amomi, the Radix Rehmanniae, Rhizoma Alismatis, Cortex Moutan, Ramulus Cinnamomi, attached
Son, Herb Gynostemmae Pentaphylli are pulverized and mixed after being respectively prepared decoction pieces, and are mixed to prepare medicine brick mixture with described final concentrated solution；
5) by described mixture punch forming drying and shaping, finished medicines brick is prepared.
Method the most according to claim 6, it is characterised in that the step 4 of described method) in, by Radix Et Caulis Acanthopanacis Senticosi, Radix Rhodiolae,
Fructus Hippophae, Radix Ranunculi Ternati, Oletum Trogopterori, Flos Campsis, Herba Artemisiae Anomalae are pulverized after being also respectively prepared decoction pieces, mix with the decoction pieces ground product of other components
Close, and be together mixed to prepare mixture with described final concentrated solution.
Method the most according to claim 6, it is characterised in that described middle concentrated solution, the relative density when 50 DEG C is
1.05-1.08g/cm3；The described final concentrated solution relative density when 50 DEG C is 1.30-1.35g/cm3。
Method the most according to claim 6, it is characterised in that described step 1) in, decoct and carry out twice, add water every time
Weight be treat decocting herbs gross weight 8-12 times, each decocting time is 50-70min, and decoct every time after, filtrate crosses 300 mesh
Sieve.
Method the most according to claim 6, it is characterised in that described step 5) in, the pressing time in punching course is
2-3min, dries temperature and is 40-45 DEG C, it is preferable that baking duration is 1.5-2.5h.
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| CN201610757783.7A CN106138974A (en) | 2016-08-29 | 2016-08-29 | A kind of pharmaceutical composition improving Qi deficiency physique and a kind of medicine brick and preparation method thereof |
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| CN107261101A (en) * | 2017-08-15 | 2017-10-20 | 山东仲景健康服务有限公司 | One kind is for Qi deficiency physique massage Chinese medicine oil breast |
| CN107669887A (en) * | 2017-11-21 | 2018-02-09 | 四川新绿色药业科技发展有限公司 | A kind of medicine for improving Qi deficiency physique or health-care food composition and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107261101A (en) * | 2017-08-15 | 2017-10-20 | 山东仲景健康服务有限公司 | One kind is for Qi deficiency physique massage Chinese medicine oil breast |
| CN107669887A (en) * | 2017-11-21 | 2018-02-09 | 四川新绿色药业科技发展有限公司 | A kind of medicine for improving Qi deficiency physique or health-care food composition and preparation method thereof |
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Application publication date: 20161123 |