CN1060649C - Medicine for curing vitiligo and preparation method thereof - Google Patents
Medicine for curing vitiligo and preparation method thereof Download PDFInfo
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- CN1060649C CN1060649C CN 93114696 CN93114696A CN1060649C CN 1060649 C CN1060649 C CN 1060649C CN 93114696 CN93114696 CN 93114696 CN 93114696 A CN93114696 A CN 93114696A CN 1060649 C CN1060649 C CN 1060649C
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- medicine
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- ethanol
- treatment vitiligo
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- 239000003814 drug Substances 0.000 title claims abstract description 37
- 206010047642 Vitiligo Diseases 0.000 title claims abstract description 18
- 238000002360 preparation method Methods 0.000 title abstract description 4
- 229940079593 drug Drugs 0.000 title description 5
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 claims abstract description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 28
- 239000007788 liquid Substances 0.000 claims description 19
- 239000006071 cream Substances 0.000 claims description 11
- 239000002994 raw material Substances 0.000 claims description 11
- 241000628997 Flos Species 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 7
- 238000007654 immersion Methods 0.000 claims description 6
- 229940040145 liniment Drugs 0.000 claims description 4
- 239000000865 liniment Substances 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 3
- 210000000582 semen Anatomy 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 2
- 241001446509 Psoralea Species 0.000 abstract description 3
- 230000015572 biosynthetic process Effects 0.000 abstract description 3
- 210000004204 blood vessel Anatomy 0.000 abstract description 3
- 231100000957 no side effect Toxicity 0.000 abstract description 3
- 206010037660 Pyrexia Diseases 0.000 abstract description 2
- 239000008280 blood Substances 0.000 abstract description 2
- 210000004369 blood Anatomy 0.000 abstract description 2
- 230000017531 blood circulation Effects 0.000 abstract description 2
- 230000027950 fever generation Effects 0.000 abstract description 2
- 238000001727 in vivo Methods 0.000 abstract description 2
- 208000017983 photosensitivity disease Diseases 0.000 abstract description 2
- 231100000434 photosensitization Toxicity 0.000 abstract description 2
- 230000004936 stimulating effect Effects 0.000 abstract description 2
- 235000006463 Brassica alba Nutrition 0.000 abstract 2
- 244000140786 Brassica hirta Species 0.000 abstract 2
- 235000011371 Brassica hirta Nutrition 0.000 abstract 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 abstract 2
- 235000016639 Syzygium aromaticum Nutrition 0.000 abstract 2
- 244000223014 Syzygium aromaticum Species 0.000 abstract 2
- 244000145469 Vernonia anthelmintica Species 0.000 abstract 2
- 235000013018 Vernonia anthelmintica Nutrition 0.000 abstract 2
- 235000013399 edible fruits Nutrition 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 102000003425 Tyrosinase Human genes 0.000 abstract 1
- 108060008724 Tyrosinase Proteins 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 235000007215 black sesame Nutrition 0.000 abstract 1
- 229960003639 laurocapram Drugs 0.000 abstract 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 23
- 230000000694 effects Effects 0.000 description 9
- 238000011084 recovery Methods 0.000 description 9
- 230000001815 facial effect Effects 0.000 description 5
- 239000000049 pigment Substances 0.000 description 5
- 206010025421 Macule Diseases 0.000 description 4
- 210000001217 buttock Anatomy 0.000 description 4
- 244000030166 artemisia Species 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 230000001788 irregular Effects 0.000 description 3
- 235000010894 Artemisia argyi Nutrition 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 206010024380 Leukoderma Diseases 0.000 description 2
- 210000000038 chest Anatomy 0.000 description 2
- 210000001061 forehead Anatomy 0.000 description 2
- 241000271039 Agkistrodon Species 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 235000003826 Artemisia Nutrition 0.000 description 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 244000286663 Ficus elastica Species 0.000 description 1
- 239000009636 Huang Qi Substances 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 235000009052 artemisia Nutrition 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 239000004568 cement Substances 0.000 description 1
- 238000002648 combination therapy Methods 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 230000000916 dilatatory effect Effects 0.000 description 1
- 235000013345 egg yolk Nutrition 0.000 description 1
- 210000002969 egg yolk Anatomy 0.000 description 1
- 210000004709 eyebrow Anatomy 0.000 description 1
- 238000009313 farming Methods 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 229940041290 mannose Drugs 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- HAWPXGHAZFHHAD-UHFFFAOYSA-N mechlorethamine Chemical compound ClCCN(C)CCCl HAWPXGHAZFHHAD-UHFFFAOYSA-N 0.000 description 1
- 229960004961 mechlorethamine Drugs 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- SQBBOVROCFXYBN-UHFFFAOYSA-N methoxypsoralen Natural products C1=C2OC(=O)C(OC)=CC2=CC2=C1OC=C2 SQBBOVROCFXYBN-UHFFFAOYSA-N 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000010137 moulding (plastic) Methods 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to a medicine for treating vitiligo and a preparation method thereof. The medicine contains vernonia anthelmintica, psoralea fruit, smoked plum, and one substance or several substances prepared from clove, white mustard seed, black sesame and laurocapram, wherein the vernonia anthelmintica, the psoralea fruit and the smoked plum can activate tyrosinase in vivo, accelerates the formation of melanin and strengthen photosensitization; the clove, the white mustard seed, etc. have the functions of stimulating local pyrexia, expanding the blood vessels, soothing the channels, quickening the network vessels, activating blood circulation to dissipate blood stasis, etc. Thus, the medicine has the advantages of high cure rate, low relapse rate, short course of treatment, no side effect, simple preparation process, low cost, etc.
Description
The present invention relates to the dermopathic medicine of a kind of treatment, more particularly, relate to the dermopathic Chinese medicine composition of a kind of treatment vitiligo.
" vitiligo " claims that again " leukoderma ", the traditional Chinese medical science claim " vitiligo ", is a kind of common metabolism of pigment obstacle dermatoses, generally adopts doctor trained in Western medicine, the traditional Chinese medical science or the combined therapy of Chinese and Western medicine.As in document (1), (2), (3), reported that dialectical opinion is controlled, dialectical compound recipe, folk prescription proved recipe, external therapy and adopt Methoxypsoralen, psoralea tincture, mustine hydrochlcride ethanol etc., but these method curative effects are not ideal enough, and have side effect.In CN1045033A, a kind of " process for preparing exterior use liquid medicine for leukoderma " disclosed, it is characterized in that grinding mixing with 16 kinds of Chinese herbal medicine such as the Radix Astragali, Rhizoma Chuanxiong, the Radix Polygoni Multiflori, Cortex Dictamni, Artemisia anethoicles Mattf, Radix Aconiti Kusnezoffii, Agkistrodon and Radix Ginseng Rubra, formed in 30 days with the ethanol of 1: 1.5 ratio and 60 degree soaking in Chinese liquor of 1: 0.75 ratio, its weak point is that the preparation time is long, careless Chinese medicine kind is many, the course of treatment long and contain some famous and precious or toxicity is big medicine, price comparison height.
The purpose of this invention is to provide that a kind of cure rate height, relapse rate are low, short treating period, have no side effect, preparing process is simple, price is low treatment vitiligo medicine and compound method thereof.
Chinese medicine composition of the present invention is characterized in that mainly making with the raw material of following consumption: Caulis Vernoniae andersonii 10～25g, Fructus Psoraleae 10～20g, Fructus Mume 8～20g.
Above-mentioned Chinese medicine composition, the optimum of its consumption is: Caulis Vernoniae andersonii 15～20g, Fructus Psoraleae 15～18g, Fructus Mume 10～15g.
Above-mentioned composition can also add one or more of raw material of following consumption:
Flos Caryophylli 5～15g, its optimum is 8～10g;
Semen Sinapis Albae 5～15g, its tight good value is 8～10g;
Semen Sesami Nigrum 5～15g, its optimum is 8～10g;
Azone 1～3ml, its optimum is 1.5～2.5ml.
The ethanol of above-mentioned Chinese medicine composition the most handy 30～75% adds ethanol to 100ml, makes liniment; Also can add to 100g, make cream with cream base (or adding 5～10g egg yolk).Its compound method is as follows:
I, Caulis Vernoniae andersonii and Fructus Psoraleae are pulverized, the ratio immersion 3～5 days of (gram: milliliter) by 1: 3～5 of the ethanol with 30～75% inclines to, to obtain I liquid stand-by.
II, Flos Caryophylli and other compositions are mixed, the ethanol with 30～75% is the ratio of (gram: milliliter) by 1: 3～5, soaks 3～5 days, inclines to, must II liquid stand-by.
III, the medicine in above-mentioned two steps is used mixedly 30～50% ethanol, (gram: ratio milliliter) after the immersion, is to reduce pressure back under 40～60 ℃ of conditions to heat up in a steamer 0.5～2 hour in temperature in 1: 3～5, incline to, get III liquid, at last, I liquid, II liquid, III liquid are merged, leave standstill, get full dose (being liniment) after the filtration, or above-mentioned filtrate is evaporated to 1: 1.5～2, and join again in the cream base of forming by cream oil phase and cream water, promptly get cream.
Caulis Vernoniae andersonii of the present invention, Fructus Psoraleae and Fructus Mume can swash in vivo tryrosinase, quicken melanic formation and strengthen photosensitization, Flos Caryophylli, Semen Sinapis Albae etc. then have effects such as stimulating local pyrexia, blood vessel dilating soothing the channels and quicking the network vessels, blood circulation promoting and blood stasis dispelling, thus make that the present invention has that cure rate height, relapse rate are low, short treating period, have no side effect, advantage such as preparing process is simple, price is low.Table one is relevant case.
Table 1:
| Sequence number | Name | Age | Sex | Affected part | Area (cm2) | Medical history | Begin treatment day | The course of treatment (my god) | The result | Remarks | |
| 1 | Breathe out * * | 47 | The man | Whole body looses and spends | 2-20 does not wait | 6 | 88.8 | 53 | Be almost recovered | My wood of Kazakhstan | As embodiment 5.6.7. |
| 2 | Health * * | 45 | The man | Right front breast, buttocks loose and spend | 6-10 does not wait | 5 | 88.9 | 60 | Be almost recovered | The Xinjiang people's air defense is done | As embodiment 5.6.7. |
| 3 | Buy * * | 30 | The man | Whole body looses and spends | 2-15 does not wait | 7 | 88.10 | 57 | Recovery from illness | Kashi carrier | |
| 4 | Leaf * * | 24 | The woman | Waistline portion | 4-9 does not wait | 5 | 89.5 | 40 | ＂ | The Wu Shi intermediate court | |
| 5 | Cattle * * | 55 | The man | Neck surface | 64 | 6 | 89.5 | 43 | ＂ | Electric substation is sent in Xinjiang | |
| 6 | The merchant * * | 36 | The man | Left front forehead | 4-5 | 1 | 89.7 | 15 | ＂ | The Xinjiang medicine grinds institute | As embodiment 5.7. |
| 7 | The summer * * | 3 | The man | En on the right arm | More than 30 | 2 | 89.8 | 30 | ＂ | Xinjiang four is built | As embodiment 5.6. |
| 8 | Recklessly * * | 34 | The woman | Face, forehead, head three places | 7-9 does not wait | 2 | 89.10 | 20 | ＂ | Three branch companies are built in Xinjiang three | |
| 9 | The king * | 9 | The woman | Right oxter | 6-9 | 2 | 89.11 | 32 | ＂ | 185 companies on duty of farming ten teachers | |
| 10 | Ah * * | 37 | The man | Facial irregular | 6-9 | 7 | 89.7 | 37 | Produce effects | Pakistan state Peshawar city | Do not follow up a case by regular visits to |
| 11 | According to * * | 30 | The man | The right arm many places are irregular | 13-17 | 5 | 89.11 | 54 | ＂ | Turfan second carrier | Continue medication not with |
| 12 | Xue * * | 28 | The woman | Left side chest, all the other whole bodies loose and spend | 7、2-4 | 2 | 90.6 | 25 | Recovery from illness | The Xinjiang emporium | |
| 13 | Horse * | 7 | The woman | Whole body looses and spends | 6-9 does not wait | 2 | 90.6 | 40 | ＂ | Crow city second institute of traditional Chinese medicine | |
| 14 | Liu * * | 30 | The woman | Whole body looses and spends | 10-13 does not wait | 90.7 | 75 | Be almost recovered | Wu Shi south gate institute of traditional Chinese medicine | ||
| 15 | Wu * * | 36 | The woman | Right shoulder long strip type | 4-6 | 4 | 90.8 | 20 | Recovery from illness | Crow city self-employed entrepreneurs |
Continuous table 1:
| Sequence number | Name | Age | Sex | Affected part | Area (cm2) | Medical history | Begin treatment day | The course of treatment (my god) | The result | Remarks | |
| 16 | Liu * * | 34 | The woman | Flower looses for the crown, face, left eye bight | 8-9 | 3 | 90.7 | 38 | ＂ | Dragon's fountain street, crow city | |
| 17 | Horse * * | 33 | The woman | Facial | 8 | 3 | 90.8 | 30 | ＂ | Tianshan Mountains plastic molding and processing plant | |
| 18 | The king * * | 50 | The man | Nose, two the back of the hand, right arm are irregular to loose | %15 does not wait | 4 | 90.9 | 45 | ＂ | Xinjiang Electrical Installing Company | |
| 19 | Tall * * | 19 | The woman | Lower back looses and spends | 8-14 does not wait | 4 | 90.10 | 65 | ＂ | Xi'an 35075 factories 6 workshops | |
| 20 | Song * * | 37 | The man | Whole body looses and spends | 10-20 does not wait | 91.6 | 56 | Be almost recovered | Xinjiang Yi Li hydroelectric board | ||
| 21 | Ah * * | 50 | The man | Flower looses at the palm back | 6-8 does not wait | 2 | 91.7 | 43 | Recovery from illness | Hotan Luopu County water conservancy | |
| 22 | Chinese mugwort * * | 40 | The man | Neck portion | 8-10 does not wait | 3 | 91.8 | 37 | Recovery from illness | Ku Che the second light industry bureau | |
| 23 | Du * * | 32 | The woman | Right side back portion | 6 | 3 | 91.8 | 25 | ＂ | Xinjiang Party school of formation | |
| 24 | 5 * * | 23 | The woman | Right back | 7-9 | 4 | 91.8 | 37 | ＂ | Xinjiang district five builds | |
| 25 | Chinese mugwort * * | 65 | The man | Two palm backs | 6-8 does not wait | 4 | 91.9 | 35 | ＂ | Xinjiang Federation of Literary and Art Circles | |
| 26 | Horse * * | 53 | The man | Two arms, the palm back of the body, two shanks | 2-15 does not wait | 6 | 91.9 | 69 | Produce effects | Changji law court | |
| 27 | Tell * * | 55 | The woman | The right eye upper eyebrow | 4-6 | 3 | 91.9 | 25 | Recovery from illness | Xinjiang film company | |
| 28 | The king * * | 40 | The woman | Buttocks looses and spends | 4-8 does not wait | 3 | 91.10 | 43 | Produce effects | Crow city first rubber plant | As embodiment 1.2. |
| 29 | Yellow * * | 65 | The man | Whole body looses and spends | 3-15 does not wait | 16 | 91.10 | 70 | ＂ | Xinjiang Comprehensive Electrical Motor Factory | |
| 30 | Open * * | 45 | The man | Whole body looses and spends | 2-18 does not wait | 7 | 91.11 | 47 | Effectively | Xinjiang oils and fats company | Do not adhere to medication |
Continuous table 1:
Annotate: 1, recovery from illness: white macula place pigment recovers normal fully.2, produce effects: white macula place pigment recovers more than 4/5.
| Sequence number | Name | Age | Sex | Affected part | Area (cm2) | Medical history | Begin treatment day | The course of treatment (my god) | The result | Remarks | |
| 31 | Grandson * * | 50 | The man | Facial | 6-9 | 5 | 91.6 | 42 | Be almost recovered | Chaoyang District Beijing shop township | |
| 32 | Open * | 17 | The woman | Buttocks | 13-18 does not wait | 6 | 91.10 | 64 | Produce effects | The comprehensive welfare country of Wu Shi | |
| 33 | Zhao * * | 27 | The woman | Chest | 8 | 3 | 91.10 | 30 | Recovery from illness | The cotton mill, Kuitun | |
| 34 | Yuan * * | 21 | The man | Buccal, the right side | 8-10 | 4 | 91.5 | 47 | Produce effects | Bayi Agricultural College, Xinjiang | |
| 35 | The king * * | 27 | The woman | Facial | 6 | 2 | 91.6 | 35 | Recovery from illness | Two in Fukang, Xinjiang county | |
| 36 | Cattle * * | 57 | The man | Whole body looses and spends | 10-20 does not wait | 7 | 91.7 | 46 | Effectively | Xinjiang Electrical Installing Company | Do not continue medication |
| 37 | Zhao * * | 23 | The woman | Two oxters | 5-13 does not wait | 4 | 91.7 | 45 | ＂ | The cement plant, Xinjiang | |
| 38 | Liu * * | 38 | The man | Facial | 8 | 3 | 91.8 | 27 | ＂ | Two in crow city bus department | Do not continue medication |
| 39 | Horse * * | 50 | The man | Whole body looses and spends | 10-15 does not wait | 10 | 91.8 | 57 | ＂ | Crow city Vegetable Company | |
| 40 | Tooth * * | 50 | The man | Two shanks | 12-14 does not wait | 8 | 91.9 | 68 | ＂ | Markit County, Xinjiang county Party committee | Do not continue to follow up a case by regular visits to as embodiment 1 |
| 41 | The king * * | 47 | The man | Buttocks | 8-12 does not wait | 6 | 89.7 | 87 | ＂ | The crow long-distance hotel self-employed entrepreneurs in city | Ceng Danyong prescription component DeGrain, after to use embodiment 5,6 instead effective |
3, effective: the white macula place has point-like pigment island to occur.4, invalid: use after one month, white macula place non-pigment recovers.
Be described further below in conjunction with table 2 pair embodiments of the invention.
In the table 2, embodiment 1～5 is a liniment, and embodiment 6～7 is a cream.
Claims (11)
1, a kind of treatment vitiligo medicine is characterized in that mainly making with the raw material of following consumption: Caulis Vernoniae andersonii 10～25g; Fructus Psoraleae 10～20g; Fructus Mume 8～20g.
2, treatment vitiligo medicine as claimed in claim 1 is characterized in that mainly making with the raw material of following consumption: Caulis Vernoniae andersonii 15～20g; Fructus Psoraleae 15～18g; Fructus Mume 10～15g.
3, treatment vitiligo medicine as claimed in claim 1 or 2 is characterized in that also having Flos Caryophylli 5～15g in the raw material.
4, treatment vitiligo medicine as claimed in claim 1 or 2 is characterized in that also having Semen Sinapis Albae 5～15g in the raw material.
5, treatment vitiligo medicine as claimed in claim 1 or 2 is characterized in that also having Semen Sesami Nigrum 5～15g in the raw material.
6, treatment vitiligo medicine as claimed in claim 1 or 2 is characterized in that also having azone 1～3ml in the raw material.
7, treatment vitiligo medicine as claimed in claim 1 or 2 is characterized in that also having Flos Caryophylli 8～10g in the raw material; Semen Sinapis Albae 8～10g; Semen Sesami Nigrum 8～10g; Azone 1.5～2.5ml.
8, treatment vitiligo medicine as claimed in claim 7 is characterized in that it is a kind of liniment.
9, treatment vitiligo medicine as claimed in claim 7 is characterized in that it is a kind of cream.
10, treatment vitiligo medicine as claimed in claim 8 is characterized in that with following method formulated:
I, Caulis Vernoniae andersonii Caulis Vernoniae andersonii, Fructus Psoraleae are pulverized, the ethanol with 30～75% is in 1: 3～5 ratio immersion 3～5 days, inclines to, to obtain I liquid stand-by;
II, Flos Caryophylli and other raw material are mixed, the ethanol with 30～75% soaked 3～5 days in 1: 3～5 ratio, inclined to, must II liquid stand-by;
III, the medicine in above-mentioned two steps is used mixedly 30～50% ethanol, ratio in 1: 3～5, after the immersion, in temperature is to reduce pressure back under 40～60 ℃ of conditions to heat up in a steamer 0.5～2 hour, incline to, get III liquid, last, I liquid, II liquid, III liquid are merged, leave standstill, add 30～75% ethanol after the filtration to 100ml.
11, treatment vitiligo medicine as claimed in claim 9 is characterized in that with following method formulated:
I, Caulis Vernoniae andersonii Caulis Vernoniae andersonii, Fructus Psoraleae are pulverized, the ethanol with 30～75% is in 1: 3～5 ratio immersion 3～5 days, inclines to, to obtain I liquid stand-by;
II, Flos Caryophylli and other raw material mix, and the ethanol with 30～75% soaked 3～5 days in 1: 3～5 ratio, incline to, must II liquid stand-by;
III, the medicine in above-mentioned two steps is used mixedly 30～50% ethanol, ratio in 1: 3～5, after the immersion, under temperature is 40～60 ℃ of 2 condition, reduce pressure back and heat up in a steamer 0.5～2 hour, incline to, III liquid, last, I liquid, II liquid, III liquid are merged, leave standstill, after the filtration filtrate is evaporated to 1: 1.5～2, join the cream base formed by cream oil phase and cream water again to 100g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93114696 CN1060649C (en) | 1992-12-12 | 1993-11-09 | Medicine for curing vitiligo and preparation method thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN92113881.4 | 1992-12-12 | ||
| CN92113881 | 1992-12-12 | ||
| CN 93114696 CN1060649C (en) | 1992-12-12 | 1993-11-09 | Medicine for curing vitiligo and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1089861A CN1089861A (en) | 1994-07-27 |
| CN1060649C true CN1060649C (en) | 2001-01-17 |
Family
ID=25742847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 93114696 Expired - Lifetime CN1060649C (en) | 1992-12-12 | 1993-11-09 | Medicine for curing vitiligo and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1060649C (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1049146C (en) * | 1995-07-21 | 2000-02-09 | 王琨宣 | Compound Vernonia anthelmintica tablet for treating vitiligo |
| CN1325068C (en) * | 2004-12-17 | 2007-07-11 | 斯拉甫·艾白 | Application of vernonia anthelmintica injection in treating cough and asthma in remission stage |
| FR2904555B1 (en) * | 2006-08-03 | 2013-12-27 | Soc Extraction Principes Actif | USE OF A COLZA EXTRACT AS AN ACTIVE AGENT TO INCREASE THE SYNTHESIS OF MELANIN IN MELANOCYTES |
| WO2008125237A2 (en) | 2007-04-17 | 2008-10-23 | Bayer Consumer Care Ag | Use of vernonia appendiculata extract for improving the skin status |
| CN101099822B (en) * | 2007-07-19 | 2010-06-09 | 中国科学院新疆理化技术研究所 | Vitiligo liniment |
| CN102688318B (en) * | 2012-04-19 | 2013-08-21 | 田杰 | Traditional Chinese medicine composition for treating segmental vitiligo |
-
1993
- 1993-11-09 CN CN 93114696 patent/CN1060649C/en not_active Expired - Lifetime
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| Publication number | Publication date |
|---|---|
| CN1089861A (en) | 1994-07-27 |
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