CN106036823A - Health-care product and preparation method thereof - Google Patents
Health-care product and preparation method thereof Download PDFInfo
- Publication number
- CN106036823A CN106036823A CN201610346151.1A CN201610346151A CN106036823A CN 106036823 A CN106036823 A CN 106036823A CN 201610346151 A CN201610346151 A CN 201610346151A CN 106036823 A CN106036823 A CN 106036823A
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- China
- Prior art keywords
- vitamin
- calcium
- health product
- soluble
- health
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 238000004519 manufacturing process Methods 0.000 title description 5
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 55
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims abstract description 27
- 229960000304 folic acid Drugs 0.000 claims abstract description 27
- 235000019152 folic acid Nutrition 0.000 claims abstract description 27
- 239000011724 folic acid Substances 0.000 claims abstract description 27
- 239000002994 raw material Substances 0.000 claims abstract description 23
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 20
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims abstract description 20
- 229960003237 betaine Drugs 0.000 claims abstract description 20
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims abstract description 15
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229960001231 choline Drugs 0.000 claims abstract description 15
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 claims abstract description 15
- 239000011669 selenium Substances 0.000 claims abstract description 15
- 229910052711 selenium Inorganic materials 0.000 claims abstract description 15
- 239000011701 zinc Substances 0.000 claims abstract description 15
- 229930003451 Vitamin B1 Natural products 0.000 claims abstract description 14
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims abstract description 14
- 229960003495 thiamine Drugs 0.000 claims abstract description 14
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims abstract description 14
- 235000010374 vitamin B1 Nutrition 0.000 claims abstract description 14
- 239000011691 vitamin B1 Substances 0.000 claims abstract description 14
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims abstract description 13
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000011575 calcium Substances 0.000 claims abstract description 13
- 229910052791 calcium Inorganic materials 0.000 claims abstract description 13
- 235000001465 calcium Nutrition 0.000 claims abstract description 13
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229960003512 nicotinic acid Drugs 0.000 claims abstract description 12
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000011777 magnesium Substances 0.000 claims abstract description 11
- 229910052749 magnesium Inorganic materials 0.000 claims abstract description 11
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 11
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims abstract description 10
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229930003779 Vitamin B12 Natural products 0.000 claims abstract description 10
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 10
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 claims abstract description 10
- 235000019163 vitamin B12 Nutrition 0.000 claims abstract description 10
- 239000011715 vitamin B12 Substances 0.000 claims abstract description 10
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 10
- 239000011718 vitamin C Substances 0.000 claims abstract description 10
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229940011671 vitamin b6 Drugs 0.000 claims abstract description 8
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 claims abstract description 7
- 235000019158 vitamin B6 Nutrition 0.000 claims abstract description 7
- 239000011726 vitamin B6 Substances 0.000 claims abstract description 7
- 229910052742 iron Inorganic materials 0.000 claims abstract description 5
- 230000036541 health Effects 0.000 claims description 53
- 239000000047 product Substances 0.000 claims description 45
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 26
- 239000000203 mixture Substances 0.000 claims description 20
- 239000000706 filtrate Substances 0.000 claims description 16
- 229940088594 vitamin Drugs 0.000 claims description 16
- 229930003231 vitamin Natural products 0.000 claims description 16
- 235000013343 vitamin Nutrition 0.000 claims description 16
- 239000011782 vitamin Substances 0.000 claims description 16
- 229940091258 selenium supplement Drugs 0.000 claims description 13
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 12
- 229960005069 calcium Drugs 0.000 claims description 11
- 238000004321 preservation Methods 0.000 claims description 11
- 238000003756 stirring Methods 0.000 claims description 11
- DFPAKSUCGFBDDF-UHFFFAOYSA-N nicotinic acid amide Natural products NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 9
- 230000001954 sterilising effect Effects 0.000 claims description 9
- 235000019160 vitamin B3 Nutrition 0.000 claims description 9
- 239000011708 vitamin B3 Substances 0.000 claims description 9
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 8
- 229930003537 Vitamin B3 Natural products 0.000 claims description 8
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 8
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 8
- 235000010755 mineral Nutrition 0.000 claims description 8
- 239000011707 mineral Substances 0.000 claims description 8
- 239000004744 fabric Substances 0.000 claims description 7
- 239000002904 solvent Substances 0.000 claims description 7
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical group [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 6
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 6
- 229930003571 Vitamin B5 Natural products 0.000 claims description 6
- 229930003756 Vitamin B7 Natural products 0.000 claims description 6
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 claims description 6
- 229960002079 calcium pantothenate Drugs 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 235000009492 vitamin B5 Nutrition 0.000 claims description 6
- 239000011675 vitamin B5 Substances 0.000 claims description 6
- 235000011912 vitamin B7 Nutrition 0.000 claims description 6
- 239000011735 vitamin B7 Substances 0.000 claims description 6
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 5
- 239000002253 acid Substances 0.000 claims description 5
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical compound [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 claims description 5
- 235000013925 ferrous lactate Nutrition 0.000 claims description 5
- 239000000395 magnesium oxide Substances 0.000 claims description 5
- CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 claims description 5
- AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 claims description 5
- 239000011781 sodium selenite Substances 0.000 claims description 5
- 235000015921 sodium selenite Nutrition 0.000 claims description 5
- 229960001471 sodium selenite Drugs 0.000 claims description 5
- PMVSDNDAUGGCCE-TYYBGVCCSA-L Ferrous fumarate Chemical compound [Fe+2].[O-]C(=O)\C=C\C([O-])=O PMVSDNDAUGGCCE-TYYBGVCCSA-L 0.000 claims description 4
- DKKCQDROTDCQOR-UHFFFAOYSA-L Ferrous lactate Chemical compound [Fe+2].CC(O)C([O-])=O.CC(O)C([O-])=O DKKCQDROTDCQOR-UHFFFAOYSA-L 0.000 claims description 4
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims description 4
- VSGNNIFQASZAOI-UHFFFAOYSA-L calcium acetate Chemical compound [Ca+2].CC([O-])=O.CC([O-])=O VSGNNIFQASZAOI-UHFFFAOYSA-L 0.000 claims description 4
- 239000001639 calcium acetate Substances 0.000 claims description 4
- 235000011092 calcium acetate Nutrition 0.000 claims description 4
- 229960005147 calcium acetate Drugs 0.000 claims description 4
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 claims description 4
- 239000001354 calcium citrate Substances 0.000 claims description 4
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 4
- 239000011773 ferrous fumarate Substances 0.000 claims description 4
- 235000002332 ferrous fumarate Nutrition 0.000 claims description 4
- 229960000225 ferrous fumarate Drugs 0.000 claims description 4
- 239000004225 ferrous lactate Substances 0.000 claims description 4
- 229940037907 ferrous lactate Drugs 0.000 claims description 4
- 229960001781 ferrous sulfate Drugs 0.000 claims description 4
- 239000011790 ferrous sulphate Substances 0.000 claims description 4
- 235000003891 ferrous sulphate Nutrition 0.000 claims description 4
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 claims description 4
- 229910000359 iron(II) sulfate Inorganic materials 0.000 claims description 4
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims description 4
- 235000019341 magnesium sulphate Nutrition 0.000 claims description 4
- 235000013337 tricalcium citrate Nutrition 0.000 claims description 4
- 239000011670 zinc gluconate Substances 0.000 claims description 4
- 235000011478 zinc gluconate Nutrition 0.000 claims description 4
- 229960000306 zinc gluconate Drugs 0.000 claims description 4
- 239000011787 zinc oxide Substances 0.000 claims description 4
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 3
- 235000002710 Ilex cornuta Nutrition 0.000 claims description 3
- 241001310146 Ilex cornuta Species 0.000 claims description 3
- 235000010326 Osmanthus heterophyllus Nutrition 0.000 claims description 3
- MDXRFOWKIZPNTA-UHFFFAOYSA-L butanedioate;iron(2+) Chemical compound [Fe+2].[O-]C(=O)CCC([O-])=O MDXRFOWKIZPNTA-UHFFFAOYSA-L 0.000 claims description 3
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 3
- 239000001110 calcium chloride Substances 0.000 claims description 3
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 3
- 235000011148 calcium chloride Nutrition 0.000 claims description 3
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims description 3
- 239000001506 calcium phosphate Substances 0.000 claims description 3
- MKJXYGKVIBWPFZ-CEOVSRFSSA-L calcium;(2s)-2-hydroxypropanoate Chemical compound [Ca+2].C[C@H](O)C([O-])=O.C[C@H](O)C([O-])=O MKJXYGKVIBWPFZ-CEOVSRFSSA-L 0.000 claims description 3
- QXDHJHQRJCJRAU-UHFFFAOYSA-N calcium;2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound [Ca].OC(=O)CC(O)(C(O)=O)CC(O)=O QXDHJHQRJCJRAU-UHFFFAOYSA-N 0.000 claims description 3
- 235000019700 dicalcium phosphate Nutrition 0.000 claims description 3
- 229960001604 ferrous succinate Drugs 0.000 claims description 3
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 claims description 3
- 239000001095 magnesium carbonate Substances 0.000 claims description 3
- 229910000021 magnesium carbonate Inorganic materials 0.000 claims description 3
- 229910001629 magnesium chloride Inorganic materials 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 3
- 229940078499 tricalcium phosphate Drugs 0.000 claims description 3
- 235000019731 tricalcium phosphate Nutrition 0.000 claims description 3
- 229910000391 tricalcium phosphate Inorganic materials 0.000 claims description 3
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims description 3
- 229960001763 zinc sulfate Drugs 0.000 claims description 3
- 229910000368 zinc sulfate Inorganic materials 0.000 claims description 3
- 241000196324 Embryophyta Species 0.000 claims description 2
- 235000011132 calcium sulphate Nutrition 0.000 claims description 2
- 239000002775 capsule Substances 0.000 claims description 2
- 239000004222 ferrous gluconate Substances 0.000 claims description 2
- 235000013924 ferrous gluconate Nutrition 0.000 claims description 2
- 229960001645 ferrous gluconate Drugs 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- VRIVJOXICYMTAG-IYEMJOQQSA-L iron(ii) gluconate Chemical compound [Fe+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O VRIVJOXICYMTAG-IYEMJOQQSA-L 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 claims 2
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 claims 1
- 239000000174 gluconic acid Substances 0.000 claims 1
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- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract description 25
- 230000000694 effects Effects 0.000 abstract description 18
- FFFHZYDWPBMWHY-VKHMYHEASA-N L-homocysteine Chemical compound OC(=O)[C@@H](N)CCS FFFHZYDWPBMWHY-VKHMYHEASA-N 0.000 abstract description 16
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 abstract description 15
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- ZNOVTXRBGFNYRX-ABLWVSNPSA-N levomefolic acid Chemical compound C1NC=2NC(N)=NC(=O)C=2N(C)C1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 ZNOVTXRBGFNYRX-ABLWVSNPSA-N 0.000 abstract description 4
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a health-care product and a preparation method thereof. The health-care product is prepared from the following raw materials of folic acid, betaine, choline, vitamin B1, vitamin B2, niacin, pantothenic acid, vitamin B6, vitamin B12, biotin, vitamin C, soluble zinc, soluble selenium, soluble magnesium, soluble calcium and soluble iron. The health-care product disclosed by the invention has the beneficial effects that the choline and the betaine provide methyl, the folic acid transfers the methyl, and the methyl is used for methylating DNA and protein; the vitamins B2 and Vc contribute to conversion of the folic acid into 5-methyltetrahydrofolic acid, so that the methyl transfer capacity is improved; B12 is used as a coenzyme to be used for promoting transformation of homocysteine, so that occurrence of vascular diseases is prevented; and selenium, zinc, magnesium and calcium can improve the activity of resultant-glutathione. The Vc and selenium glutathione form an oxidation resistant network, so that the self antioxidant ability of bodies is improved as a whole. The health-care product disclosed by the invention has the efficacies of promoting normal methylating level, reducing the homocysteine and improving the self antioxidant ability of the bodies.
Description
Technical field
The present invention relates to a kind of health product, be specifically related to a kind of health product and preparation method thereof.
Background technology
Present social goods and materials enrich, and material life is obviously improved, but still have substantial amounts of people to be faced with what nutrient lacked
State, especially rhythm of life are fast, diet works and rests irregular crowd and some patients with chronic diseases.
Some disease is that DNA mutation causes in more the thinking of people in the past, proves now with sufficient evidence
A lot of diseases are not that DNA mutation causes, but DNA modification there is a problem, the modification of DNA causes the ANOMALOUS VARIATIONS quilt of body
It is referred to as epigenetics.In epigenetics the most studied and it is found out that DNA's methylates, have the most again histone
Methylate, and acetylation, phosphorylation etc..And these are mostly important to methylate in modifying.
DNA methylation refers to the organism catalysis at dnmt rna (DNA methyltransferase, DMT)
Under, with s-S-adenosylmethionine (SAM) as methyl donor, methyl is transferred to the process in specific base.Undermethylation
Can cause kinds of tumors such as ovarian cancer, cervical cancer, pulmonary carcinoma, acute lymphoblastic leukemia, gastric cancer, the esophageal carcinoma, cancer of pancreas and
Cardiovascular and cerebrovascular disease and immune disease.
Methylating is a kind of important modification of protein and nucleic acid, the expression of regulator gene and closedown, with cancer, decline
Always, the numerous disease such as senile dementia closely related, be one of the important research content of epigenetics.Modal methylating is repaiied
It is decorated with DNA methylation and histone methylated.
DNA methylation can close the activity of some gene, can cause chromatin Structure, DNA conformation, DNA stability and DNA
With the change of protein interaction mode, thus control gene expression.Research confirms, the first of cytosine in CpG dinucleotide
Base result in the heredopathia that human body more than 1/3 causes due to base transition.Germ cell development period mammal
With the preimplantation embryo phase, the methylation patterns in its genome range pass through large-scale demethylation and ensuing methyl again
Change process reprograms, thus produces the cell with potentiality of development；During cell breaks up, the shape that methylates of gene
State will entail progeny cell.Due to DNA methylation and human developmental and the substantial connection of tumor disease, particularly CpG island first
Antioncogene transcriptional inactivation problem caused by base, DNA methylation has become as the important of epigenetics and epigenomics
Research contents.
There is methylating, by histone on H3 and H4 histone N end Arg or Lys residue in histone methylated referring to
Transmethylase mediation catalysis.Histone methylated function is mainly reflected in heterochromatin formation, Genomic Imprinting, X chromosome
Inactivation and transcriptional control aspect.
Currently for the medicine of DNA methylation less than 5 kinds, more useful for preventing various aberrant methylations to be difficult to play
Effect.DNA methylation, the histone methylated methyl having relied on SAM raising.SAM
Deficiency will cause methylated exception.SAM produces homocysteine after providing methyl, and homocysteine can
Generating methionine with one methyl of re-absorption, methionine combines ATP and produces SAM.Homocysteine be as in
Between a metabolite, its absorb methyl derive from two approach.Approach one is glycine betaine approach, and glycine betaine is also known as front three
Base glycine, first methyl wherein sloughed directly feeds homocysteine and produces methionine, and this process is only at liver, kidney
Carry out in dirty.Approach two is folic acid approach, and the glycine betaine sloughing a methyl is referred to as dimethylglycine, and dimethylglycine is again
Sloughing two methyl and generate glycine, the two methyl supply folic acid generates the 5-methyltetrahydrofolate of activity, then by 5-methyl
Tetrahydrofolic acid supply homocysteine generates methionine, and this process occurs at whole body.Therefore, glycine betaine is whole body methyl
Supplier is again the transporter in Liver and kidney, and folic acid is the transporter acting on whole body everywhere.Therefore a kind of methyl is invented
The health product that supplier and transporter combine are conducive to keeping the normal methyl group of body.
Choline produces glycine betaine through peroxidating in vivo, and therefore, choline is also a kind of good methyl group provider.
Homocysteine is the insalubrious aminoacid of one found recently, and it can injure vascular endothelial cell,
Cause the formation of the hardening of blood vessel, thrombosis.Therefore the level reducing homocysteine contributes to preventing the generation of body illness.
Have now found that high-caliber homocysteine with hypertension, apoplexy, osteoporosis, cardiovascular disease, nervous system disease,
Abnormal development etc. all have close relationship.Reduce homocysteine at present to be typically, with folic acid, B6, B12, to be rarely employed Radix Betae
Alkali or choline.Health product or medicine that a folic acid, B6, B12 combine more is not had with glycine betaine, choline on market.This
Invention combination contain supplier and the transporter being supplied to homocysteine methyl, be more provided that abundance methyl and
Effectively reduce the level of homocysteine.
In addition to the generation that aberrant methylation and homocysteine can cause disease, radical damage is often disease
The first step occurred.The body of people have self exist oxidation resistance, self produce antioxidant mainly have SOD,
CAT and glutathion.The most powerful anti-oxidation function of body is antioxidant network, and antioxidant network is by Vc, Ve, coenzyme Q10, sulfur
Octanoic acid forms with glutathion selenium, plays the mutual transformation of oxidation-reduction, collaborative antioxidation thus the overall body that improves
Intrinsic antioxidative ability, it is achieved free radical balances, and prevents radical damage cell.Glutathion is as main the resisting of health
One of oxide, its synthesis comes from glutamic acid, cysteine, glycine.Wherein cysteine comes from homocysteine
Conversion, glycine comes from glycine betaine provides the product after three methyl.Therefore at folic acid, B6, B12 and glycine betaine, choline
Combination reduces after homocysteine, and its product cysteine, glycine can more synthesizing glutathions.Selenium, zinc,
Magnesium, calcium can improve the activity of glutathion.Glutathion only combines selenium just can play antioxidation, zinc, calcium, magnesium energy
Improve the oxidation resistance of glutathion further.
Summary of the invention
It is an object of the invention to provide a kind of health product containing vitamin and mineral and preparation method thereof.
It is an object of the invention to be achieved through the following technical solutions:
A kind of health product, including the raw material of following weight parts, folic acid 0.12-0.4 part and glycine betaine 200-2000 part.
Further, described health product also include vitamin and mineral.
Described vitamin includes vitamin B1 0.4-2 part, vitamin B2 0.3-1.5 part, vitamin B3 3-14 part, dimension
Raw element B5 1-6 part, vitamin B6 0.6-3 part, vitamin B12 0.001-0.1 part, vitamin B7 0.02-0.04 part, dimension life
Element C 30-120 part.
Further, described mineral includes: soluble selenium 0.02-0.1 part, soluble Zn 8-30 part, soluble magnesium
600-2600 part, soluble iron 12-50 part, solubility calcium 1500-7500 part.
Further, described health product also include choline 100-500 part.
Further, the one during described soluble selenium is sodium selenite, selenium yeast or its mixture；Soluble Zn is sulfur
Acid zinc, Chinese holly edge acid zinc, zinc oxide and one or more mixture of zinc gluconate；Described soluble magnesium is chlorination
One or more mixture in magnesium, magnesium carbonate, magnesium sulfate and magnesium oxide；Soluble iron is ferrous fumarate, Fructus Vitis viniferae
A kind of in saccharic acid ferrous iron, ferrous sulfate, ferrous succinate and ferrous lactate or the mixture that they are two or more；Described solubility
Calcium is calcium carbonate, calcium acetate, Citric acid calcium, calcium chloride, calcium citrate, calcium gluconate, calcium hydrogen phosphate, calcium sulfate, tricresyl phosphate
A kind of in calcium and L-calcium lactate or the mixture that they are two or more.
The preparation method of health product described above comprises the following steps:
(1) each raw material is added to the water mixing and stirring and becomes mixed liquor；
(2) by step (1) gained mixed liquor cold preservation a period of time, filter to get filtrate；
(3) concentrated filtrate, is dried, and sterilize to obtain health product.
Further, step (1) described water is for being heated to 100 DEG C, then naturally cools to the water of 40-45 DEG C；Step (1) institute
The mixing speed stating stirring is 30-100r/min, and stirring to raw material is completely dissolved；Step (2) described cold preservation be subzero 10 DEG C-
Under conditions of 0 DEG C, cold preservation 12-16h；Described being filtered into is filtered with the filter cloth of 1000-2000 mesh.
Further, in step (3), concentrated filtrate removes solvent；Described be dried under conditions of 40-50 DEG C be dried 24-
36h, described sterilizing is sterilizing 30-40min under conditions of 80-90 DEG C.
Described health product are granule, tablet, capsule or oral liquid.
Folic acid is also FA, being a kind of water soluble vitamins, finding this biotic factor, so being ordered from Herba Spinaciae
Entitled folic acid, folic acid, rich in fresh water fruits and vegetables, meat product, has the effect promoting that in bone marrow, juvenile cell is ripe, people
Class can cause megaloblastic anemia and leukopenia as lacked folic acid, is even more important anemia of pregnant woman.Folic acid is that human body is in profit
By necessary material when sugar and aminoacid, being body cell growth and the necessary material of breeding, folic acid helps protein
Metabolism, and collectively promote erythrocytic generation and maturation with vitamin B12, it is to manufacture the indispensable material of erythrocyte.Additionally,
Folic acid is also the indispensable nutrient of embryo growth and development, and anemia of pregnant woman lacks folic acid and is likely to result in during fetal birth occurring low body
Weight, heart defect etc..
Glycine betaine is a kind of alkaline matter, has strong moisture pick-up properties, can be from the root of natural plants, stem, leaf and fruit
Middle extraction or employing trimethylamine and monoxone are raw material chemosynthesis.There is antitumor, blood pressure lowering, anti-peptic ulcer and gastrointestinal
Handicapped effect, in addition glycine betaine have provide somagenic need methyl, regulate internal osmotic pressure, relax stress, promote
Lipid metabolism and protein synthesis.
Vitamin in the prevention of vitamin B1 primary treatment Vitamin B1 deficiency and treatment, vitamin B1 and all B races
Equally, unnecessary vitamin B1 will not be stored in internal, and can be completely exhausted out external, therefore it is necessary to every day supplements.Vitamin B1
Participate in the metabolism of saccharide in vivo, between the vitamin of B race, have synergism, so the dimension once absorbing whole B race is raw
Element, more preferable than the effect absorbed respectively.Vitamin B1 is referred to as psychogenic vitamin, because vitamin B1 is to nervous tissue
Desirable influence is had with the mental status.
Vitamin B2 is again riboflavin, is slightly soluble in water, and in neutrality or alkaline solution, heating is stable.If internal shortage
Vitamin B2 can affect the biological oxidation of body, makes metabolism generation obstacle.During the storage of internal vitamin B2 the most limited, so
Every day will supplement.The major physiological functions of vitamin B2 is to promote metabolism, vitamin B2 and specific protein as coenzyme
In conjunction with producing yellow enzyme, yellow enzyme plays the effect of transmission hydrogen in substance metabolism, participates in the respiratory of tissue.
Vitamin B3 is also nicotinic acid or vitamin PP, is one of 13 kinds of vitamin of needed by human.Nicotinic acid turns in human body
Turn to nicotiamide, nicotiamide is cozymase and the ingredient of codehydrogenase Ⅱ, participates in HypercholesterolemicRats, the oxidation of Tissue respiration
Journey and the process of saccharide anaerobic decomposition.Nicotinic acid has the effect of stronger expansion peripheral vessels, is clinically used for treating headache, inclined head
Pain, the symptom such as tinnitus, there is the health of facilitating digestion system, alleviate gastrointestinal disorders, make that skin is more healthy, blood circulation promoting, make
Effect of blood pressure drops.
Vitamin B5 is again pantothenic acid, Nicotinicum Acidum, for white powder, has the function manufacturing antibody, is safeguarding hair, skin
Skin and blood health aspect play key player.
Vitamin B6 is also known as pyridoxin, in vivo presented in phosphate ester, is a kind of water soluble vitamins.Vitamin
The constituent of B6 behaviour some coenzyme internal, participates in multiple metabolic response, especially has substantial connection with amino acid metabolism.Dimension
Raw element B6 mainly acts on the blood of human body, muscle, nerve, skin etc., has and promotes the synthesis of antibody, maintains sodium, potassium balance
Effect.
Vitamin B7, also known as biotin, is water soluble vitamins, falls within vitamin B complex, and it is synthetic vitamin C
Necessary material, is fat and the indispensable material of protein homergy, is a kind of human body natural of maintenance growth, grows and just
The nutrient that ordinary person's body functional health is necessary.Having and maintain the complete and sound of epithelial structures, enhancing human body immunity reacts
The effect grown with resistance, maintenance normal growth.
Vitamin B12 is the class complex organic compound containing cobalt, has the erythrocytic growth of promotion and maturation, makes body
Hematopoietic function is in normal condition, prevents pernicious anemia, safeguards effect that nervous system is healthy, can increase the utilization of folic acid
Rate, promotes carbohydrate, fat and the metabolism of protein；Have elimination dysphoria, focus on, hypermnesis and flat
Effect of weighing apparatus sense.
Vitamin C is again L-AA, is a kind of water soluble vitamins, rich content in fruits and vegetables.Vitamin C
Contribute to consolidating the synthesis of cell tissue and collagen protein, the strong skeleton of energy and tooth, also can prevent gingival hemorrhage.Vitamin C
Other antioxidant can be protected, such as VitAVitE, unsaturated fatty acid, prevent the injury of radical pair human body；Make
The ferric iron back being difficult to absorb becomes ferrous iron, promotes the intestinal absorption to ferrum, improves the liver utilization rate to ferrum, helps
In treatment iron deficiency anemia.
Choline is a kind of strong organic base, is the constituent of lecithin, and choline has the energy promoting brain development with improving memory
Power, has the effect promoting liver function, the tissue of human body can be helped to get rid of toxin and medicine, contribute to treating senile dementia.
In health product of the present invention, vitamin B1, B6 and B12 contribute to protecting neural tissue cell, and vitamin B2 then has
Wheat Protein, vitamin B3 can maintain digestive system healthy, and FA can avoid half to pile up can protect with cystine
Protect cardiovascular, it is also possible to slow down the generation of senile dementia；Play synergism between multivitamin B, regulate new old generation
Thank, maintain skin and the health of muscle, increase immune system and neural function, promote cell growth and division.Dimension is raw
Element B contributes to ascorbic synthesis in body.
Zinc contributes to alleviating pressure, can promote the health of nervous system and brain；Selenium has non-oxidizability, can protect body
From free radical and carcinogenic infringement, the reaction that also can reduce inflammation, enhancing immunity thus resist infection, promote the strong of heart
Health；Magnesium can strengthen skeleton and tooth intensity, contributes to loosening all muscles thus promotes the health of muscle, premenstrual comprehensively for treatment
Levy, cardioprotection and nervous system health have important function；Ferrum is the constituent of hemoglobin, participates in oxygen and titanium dioxide
The delivery of carbon and exchange, be the composition material of enzyme, and it is also required for producing energy；Calcium be to maintain health of heart, neurological health,
Muscle contraction and the nutrient of skin, skeleton and dental health；Mineral organically mixes the acid that can maintain body
Soda balance and histiocyte osmotic pressure, maintenance neural muscle excitability and membrane passage.
The invention have the benefit that choline in health product of the present invention, glycine betaine provide methyl, folic acid transhipment first
Base, promotes DNA, the methylating of protein, and safeguards that body cell keeps normal and grows and differentiation, prevents to lead because of aberrant methylation
The tumor of cause, autoimmune disease etc.；Concurrently facilitate the level reducing homocysteine, sending out of prevention vascular conditions
Raw；Vitamin B2, B12, Vc contribute to folic acid and are converted into 5-methyltetrahydrofolate, improve methyl turn-over capacity；Promote homotype half
Cystine is converted into cysteine, improves the synthesis of glutathion, and the selenium added, zinc, magnesium, calcium can improve glutathion
Activity.The Vc added forms antioxidant network with glutathion selenium, plays the mutual transformation of oxidation-reduction, collaborative antioxygen
Change thus the overall intrinsic antioxidative ability improving body, it is achieved free radical balances, and prevents radical damage cell.Vitamin B
Play synergism between race, regulation metabolism, maintain skin and the health of muscle, increase immune system and neural
Function, promotes cell growth and division.Mineral organically mixes acid-base balance and the histiocyte that can maintain body
Osmotic pressure, maintenance neural muscle excitability and membrane passage.
Vitamin, mineral are organically mixed by the present invention has holding normal methyl group level, fall homotype half
Cystine and effect of raising body intrinsic antioxidative ability, can improve the immunity of body.
Detailed description of the invention
Embodiment one
A kind of health product, including the raw material of following weight parts: folic acid 120ug and glycine betaine 200mg.
The preparation method of health product described above, comprises the following steps:
(1) being added to the water by each raw material under conditions of low whipping speed is 30r/min, stirring is completely dissolved into mixed to raw material
Closing liquid, water used is for being heated to 100 DEG C, then naturally cools to the water of 40 DEG C；
(2) by step (1) gained mixed liquor under conditions of 0 DEG C, cold preservation 12h；Then carried out with the filter cloth of 1000 mesh
Filter to obtain filtrate；
(3) concentrated filtrate removes solvent, is dried 36h, sterilizing under conditions of 80 DEG C the most again under conditions of 40 DEG C
40min obtains health product.
Embodiment two
A kind of health product, including the raw material of following weight parts, folic acid 160ug, glycine betaine 800mg, vitamin B1 0.4mg,
Vitamin B2 0.3mg, vitamin B3 3mg, vitamin B5 1mg, vitamin B6 0.6mg, vitamin B12 1ug, vitamin
B7 20ug, vitamin C 30mg, choline 100mg, sodium selenite 20ug, zinc sulfate 8mg, magnesium chloride 600mg, ferrous fumarate
12mg, calcium carbonate 1500mg.
The preparation method of health product described above, comprises the following steps:
(1) being added to the water by each raw material under conditions of low whipping speed is 50r/min, stirring is completely dissolved into mixed to raw material
Closing liquid, water used is for being heated to 100 DEG C, then naturally cools to the water of 42 DEG C；
(2) by step (1) gained mixed liquor under conditions of subzero 3 DEG C, cold preservation 14h；Then enter with the filter cloth of 1200 mesh
Row filters to get filtrate；
(3) concentrated filtrate removes solvent, is dried 30h, sterilizing under conditions of 85 DEG C the most again under conditions of 45 DEG C
35min obtains health product.
Embodiment three
A kind of health product, including the raw material of following weight parts, folic acid 250ug, glycine betaine 1000mg, vitamin B1 1mg,
Vitamin B2 0.8mg, vitamin B3 10mg, vitamin B5 4mg, vitamin B6 2mg, vitamin B12 50ug, vitamin
B7 25ug, vitamin C 80mg, choline 300mg, selenium yeast 50ug, zinc oxide 12mg, magnesium oxide 1000mg, ferrous lactate
20mg, calcium acetate 3000mg.
The preparation method of health product described above, comprises the following steps:
(1) being added to the water by each raw material under conditions of low whipping speed is 70r/min, stirring is completely dissolved into mixed to raw material
Closing liquid, water used is for being heated to 100 DEG C, then naturally cools to the water of 43 DEG C；
(2) by step (1) gained mixed liquor under conditions of subzero 6 DEG C, cold preservation 15h；Then enter with the filter cloth of 1600 mesh
Row filters to get filtrate；
(3) concentrated filtrate removes solvent, is dried 24h, sterilizing under conditions of 90 DEG C the most again under conditions of 50 DEG C
30min obtains health product.
Embodiment four
A kind of health product, including the raw material of following weight parts, folic acid 300ug, glycine betaine 1500mg, vitamin B1
1.2mg, vitamin B2 1.2mg, vitamin B3 10mg, vitamin B5 4mg, vitamin B6 2mg, vitamin B12 80ug,
The mixture 80ug of quality, the oxidations such as vitamin B7 35ug, vitamin C 100mg, choline 400mg, sodium selenite and selenium yeast
The mixture 2000mg of quality, the ferrous sulfate such as mixture 25mg, magnesium sulfate and the magnesium oxide of the quality such as zinc and zinc gluconate
The mixture 4500mg of the quality such as mixture 45mg, tricalcium phosphate and the calcium citrate with quality such as ferrous lactates.
The preparation method of health product described above, comprises the following steps:
(1) being added to the water by each raw material under conditions of low whipping speed is 80r/min, stirring is completely dissolved into mixed to raw material
Closing liquid, water used is for being heated to 100 DEG C, then naturally cools to the water of 45 DEG C；
(2) by step (1) gained mixed liquor under conditions of subzero 8 DEG C, cold preservation 15h；Then enter with the filter cloth of 1800 mesh
Row filters to get filtrate；
(3) concentrated filtrate removes solvent, is dried 24h, sterilizing under conditions of 88 DEG C the most again under conditions of 50 DEG C
38min obtains health product.
Embodiment five
A kind of health product, including the raw material of following weight parts, folic acid 400ug, glycine betaine 2000mg, vitamin B1 2mg,
Vitamin B2 1.5mg, vitamin B3 14mg, vitamin B5 6mg, vitamin B6 3mg, vitamin B12 100ug, vitamin
The mixture 100mg of quality, zinc sulfate, the Chinese hollys such as B7 40ug, vitamin C 120mg, choline 500mg, sodium selenite and selenium yeast
The matter such as mixture 30mg, magnesium chloride, magnesium carbonate, magnesium sulfate and the magnesium oxide of the quality such as edge acid zinc, zinc oxide and zinc gluconate
The quality such as mixture 2600mg, ferrous fumarate, Ferrous gluconate, ferrous sulfate, ferrous succinate and the ferrous lactate of amount
Mixture 50mg, calcium carbonate, calcium acetate, Citric acid calcium, calcium chloride, calcium citrate, calcium gluconate, calcium hydrogen phosphate, sulphuric acid
The mixture 7500mg of the quality such as calcium, tricalcium phosphate and L-calcium lactate.
The preparation method of health product described above, comprises the following steps:
(1) each raw material is added to the water under conditions of low whipping speed is 100r/min, stirs to raw material and be completely dissolved into
Mixed liquor, water used is for being heated to 100 DEG C, then naturally cools to the water of 45 DEG C；
(2) by step (1) gained mixed liquor under conditions of subzero 10 DEG C, cold preservation 12h；Then enter with the filter cloth of 2000 mesh
Row filters to get filtrate；
(3) concentrated filtrate removes solvent, is dried 24h, sterilizing under conditions of 90 DEG C the most again under conditions of 50 DEG C
30min obtains health product.
The present invention is not limited to above-mentioned preferred forms, and anyone can show that under the enlightenment of the present invention other are various
The product of form, no matter but in its details, make any change, every have same as the present application or akin technical scheme,
Within all falling within protection scope of the present invention.
Claims (10)
1. health product, it is characterised in that include the raw material of following weight parts: folic acid 0.12-0.4 part and glycine betaine 200-
2000 parts.
Health product the most according to claim 1, it is characterised in that described health product also include vitamin and mineral.
Health product the most according to claim 2, it is characterised in that described vitamin includes: vitamin B1 0.4-2 part, dimension
Raw element B2 0.3-1.5 part, vitamin B3 3-14 part, vitamin B5 1-6 part, vitamin B6 0.6-3 part, vitamin B12
0.001-0.1 part, vitamin B7 0.02-0.04 part, vitamin C 30-120 part.
Health product the most according to claim 2, it is characterised in that described mineral includes: soluble selenium 0.02-0.1 part,
Soluble Zn 8-30 part, soluble magnesium 600-2600 part, soluble iron 12-50 part, solubility calcium 1500-7500 part.
Health product the most according to claim 1, it is characterised in that described health product also include choline 100-500 part.
Health product the most according to claim 4, it is characterised in that described soluble selenium is in sodium selenite, selenium yeast
One or its mixture；Soluble Zn is one or more of zinc sulfate, Chinese holly edge acid zinc, zinc oxide and zinc gluconate
Mixture；Described soluble magnesium is one or more the mixture in magnesium chloride, magnesium carbonate, magnesium sulfate and magnesium oxide；
Soluble iron be the one in ferrous fumarate, Ferrous gluconate, ferrous sulfate, ferrous succinate and ferrous lactate or its two
Plant above mixture；Described solubility calcium is calcium carbonate, calcium acetate, Citric acid calcium, calcium chloride, calcium citrate, gluconic acid
A kind of in calcium, calcium hydrogen phosphate, calcium sulfate, tricalcium phosphate and L-calcium lactate or the mixture that they are two or more.
7. the preparation method of the described health product of one of claim 1-6, it is characterised in that comprise the following steps:
(1) being added to the water by each raw material, stirring makes it fully dissolve, and obtains mixed liquor；
(2) by step (1) gained mixed liquor cold preservation a period of time, filter to get filtrate；
(3) concentrated filtrate, is dried, and sterilize to obtain health product.
The preparation method of health product the most according to claim 7, it is characterised in that step (1) described water is for being heated to 100
DEG C, then naturally cool to the water of 40-45 DEG C；The mixing speed of step (1) described stirring is 30-100r/min, and stirring is to raw material
It is completely dissolved；Step (2) described cold preservation is under conditions of subzero 10 DEG C-0 DEG C, cold preservation 12-16h；Described being filtered into uses 1000-
The filter cloth of 2000 mesh filters.
The preparation method of health product the most according to claim 7, it is characterised in that in step (3), concentrated filtrate removes solvent；
Described be dried under conditions of 40-50 DEG C be dried 24-36h, described sterilizing is sterilizing 30-under conditions of 80-90 DEG C
40min。
10. the described health product of one of claim 1-9 are granule, tablet, capsule or oral liquid.
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| CN115770255A (en) * | 2021-09-07 | 2023-03-10 | 深圳奥萨医药有限公司 | A composition for adjuvant treatment of cancerous fever |
| CN116746684A (en) * | 2023-07-26 | 2023-09-15 | 周宏� | A nutritional composition that improves the methylation level of the human body's entire genome |
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Application publication date: 20161026 |