CN105832594A - Traditional Chinese medicinal lipid reducing toothpaste and preparation method thereof - Google Patents
Traditional Chinese medicinal lipid reducing toothpaste and preparation method thereof Download PDFInfo
- Publication number
- CN105832594A CN105832594A CN201610213253.6A CN201610213253A CN105832594A CN 105832594 A CN105832594 A CN 105832594A CN 201610213253 A CN201610213253 A CN 201610213253A CN 105832594 A CN105832594 A CN 105832594A
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- extract
- radix
- rhizoma
- toothpaste
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- 150000002632 lipids Chemical class 0.000 title abstract description 10
- 239000000284 extract Substances 0.000 claims abstract description 546
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- 241000180649 Panax notoginseng Species 0.000 claims abstract description 72
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- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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Abstract
The invention discloses traditional Chinese medicinal lipid reducing toothpaste and a preparation method of the toothpaste, and belongs to the technical field of daily chemical products, aiming at solving the technical problem that toothpaste which has a function of preventing and treating cardiovascular and cerebrovascular diseases fails to take a health care effect for a long time to treat hyperlipoidemia since the toothpaste is single in composition and is relatively weak in lipid-reducing effect. The toothpaste consists of a toothpaste substrate, a gynostemma pentaphyllum leaf extract, a polygonum cuspidatum extract, a fleece-flower root extract, an aloe extract and a radix notoginseng extract, and further consists of 1-3 of the following extracts: a rhizoma alismatis extract, a rhubarb extract, a radix curcumae longae extract, a lucid ganoderma extract, a semen raphani extract, a capillary wormwood herb extract, a rhizoma curcumae extract, a radix curcumae extract, a cassia twig extract, a langehead atractylodes rhizome extract, a fructus sophorae extract, a radix scrophulariae extract, an extract of radix paeoniae rubra, a rhizoma drynariae extract, a rhizoma ligustici wallichii extract, a rhodiola rosea extract, a rhizoma dibotryis extract and a radix bupleuri extract. The preparation method comprises the following steps: I, preparing the toothpaste substrate; II, preparing the extracts; III, preparing a paste and filling. The toothpaste disclosed by the invention is concrete in curative effect on reducing lipid and is excellent in health care and treatment functions; and the preparation process is simple.
Description
Technical field
The invention belongs to cosmetics of everyday use technical field, be specifically related to medicated toothpaste having Antilipemic health function and preparation method thereof.
Background technology
Along with the raising of national life level, hyperlipemia and fatty liver have become current epidemic diseases.Hyperlipemia may result in
Atherosclerosis, is the important risk factor of fatal disease such as coronary heart disease, myocardial infarction, apoplexy, also increases the weight of
The principal element of the diseases such as diabetes, hypertension, pancreatitis, fatty liver, liver cirrhosis.The hyperlipemia infringement to health
Being long-term, concealment, gradually and general, majority need prolonged administration of drugs to treat.If but long-term taking
Blood fat reducing Western medicine, can damage again the healthy of patient because of side effects of pharmaceutical drugs.And some Chinese herbal medicine has reducing blood fat
Significantly effect, its toxicity is low, few side effects, can long-term prescription, there is good Antilipemic health effect.
The main active ingredient of Herb Gynostemmae Pentaphylli is gypenoside, Herb Gynostemmae Pentaphylli glucoside (polysaccharide), water-soluble amino acid, flavonoid, many
Plant vitamin, trace element, mineral etc., have effect of eliminating inflammation and expelling toxin, eliminating phlegm and stopping cough, also can treat hypertension, height
Blood fat, hyperglycemia, the disease such as fatty liver.Rhizoma Polygoni Cuspidati has dampness removing jaundice eliminating, heat-clearing and toxic substances removing, eliminating stasis to stop pain, the merit of relieving cough and resolving phlegm
Effect, can be used for antitussive, Adjust-blood lipid, reduction cholesterol, shock.The Radix Polygoni Multiflori can reduce total plasma cholesterol, triglyceride,
Free cholesterol and cholesteryl ester, delay the atherosis formation and development that beats one's brains.Aloe can blood circulation promoting, reduction
Cholesterol level, treats hyperlipemia, hypercholesterolemia.Radix Notoginseng property hardship sweet, micro-, temperature, there is dissipating blood stasis hemostasis, disappear
Effect of swollen analgesic therapy, can hemostasia and dissipation blood stasis, expand blood vessel, reduce blood pressure, blood fat reducing, improve blood microcirculation, increase blood
Flow.Rhizoma Alismatis nature and flavor are sweet salty-cold, return kidney, bladder two warp, are mainly composed of volatile oil, and extract has blood fat reducing anti-fatty liver
Composition.Radix Et Rhizoma Rhei nature and flavor bitter cold, returns spleen, stomach, large intestine, liver, the pericardium Five Classics, this medical instrument have purging heat to relax the bowels, removing mass blood stasis expelling,
The functions such as clearing away damp-heat, Radix Et Rhizoma Rhei can cause intestinal contraction, secretion to increase and produce discharge function, and Radix Et Rhizoma Rhei has blood pressure lowering, fall gallbladder
Sterin effect.Rhizoma Curcumae Longae bitter in the mouth is pungent, warm in nature, returns liver, spleen two warp, and main component contains volatile oil, can declare the gas in logical blood,
Making gas row and blood is not stopped up stagnant, can increase bile is formed and secretion, makes the cholic acid of excretion in feces and cholesterol increase, Rhizoma Curcumae Longae
Fibrinous dissolving activity can also be increased, have antithrombotic effect.Ganoderma is warm in nature, slightly sweet flavor, Ganoderma containing sterol,
Alkaloid, protein, polysaccharide etc., have effect of beneficial vital essence, bone and muscle strengthening, cure mainly metal fatigue, palpitation and insomnia, height
Blood pressure, hypercholesterolemia, cerebrovascular sclerosis etc..Semen Raphani acrid-sweet flavor, can promoting the circulation of QI dissipating depression of QI, it is turbid to dispel expectorant, adjusts dirty
Internal organs function, improves organism metabolism, promotes lipid material to drain, and accelerates cholesterol in serum and the removing of triglyceride.Mattress
Old clearing away heat-damp and promoting diuresis, jaundice eliminating, cure mainly jaundice, dysuria, eczema pruritus, infectious jaundice type hepatitis etc., pharmacology grinds
Studying carefully and have function of gallbladder promoting, liver function protecting, antipyretic, antiinflammatory, blood fat reducing, blood pressure lowering, coronary dilating etc. acts on.Rhizoma Curcumae can control promoting the circulation of QI to relieve pain,
Long-pending eliminating stagnation, removing blood stasis, have heat clearing away, removing toxic substances, and turbid effect of dispelling hinders the hyperlipemia caused for phlegm-turbidity and blood stasis.Radix Curcumae
Having promoting blood circulation to relieve pain, promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood, and the effect of depressed liver-energy dispersing and function of gallbladder promoting also has regulation immunity, improves blood
Circulation, effect of free radical resisting damage, Radix Curcumae can reduce serum cholesterol and apolipoprotein B, prevents blood vessel wall lipid heap
Long-pending.Ramulus Cinnamomi belongs to pungent and warm medicine for relieving the exterior syndrome, has the effect of dispelling cold by warming the meridian, can improve blood microcirculation pipe, pre-anti-aging, blood pressure lowering,
Blood fat reducing, blood sugar lowering, anticancer.The Rhizoma Atractylodis Macrocephalae not only can damp eliminating dampness removing, moreover it is possible to spleen invigorating, blood fat reducing, blood sugar lowering.The Fructus Sophorae has softening blood
Pipe, blood pressure lowering, cholesterol reducing, dispelling wind heat, moisten large intestine, effect of removing heat from blood relieving constipation.Radix Scrophulariae can be used for treatment due to high fat
The blood that mass formed by blood stasis causes is obstructed, and blood viscosity is high.Radix Paeoniae Rubra can clots absorbing, pain relieving, removing heat from blood, detumescence, cure mainly the stagnant amenorrhea of the stasis of blood,
The accumulation of hernia abdominal mass, stomachache, have obvious blood fat reducing, anti peroxidation of lipid, the effect of degraded plasma fibrinogen.Osteomiosis
Benefit has prevention blood fat to raise and treatment hyperlipemia effect, and can prevent the formation of Aorta atheromatous plague.Rhizoma Chuanxiong has
There is the effect of blood circulation promoting competent silt, it is possible to decrease blood viscosity, cholesterol and triglyceride.Radix Rhodiolae can effectively facilitate cholesterol and
The metabolism of fat so that it is be not deposited on blood vessel, thus reduce blood fat and blood viscosity, reduces the formation of thrombosis.Gold
Semen Fagopyri Esculenti has the effects such as blood lipid-reducing blood sugar-decreasing, eliminating phlegm and relieving cough and suppression platelet aggregation.Radix Bupleuri has hepatic cholagogic, reduces blood gallbladder
Sterin and the effect of triglyceride, can treat hyperlipemia and atherosclerosis.Above Chinese herbal medicine Bloodlipid-lowering is definite,
Toxicity is low, few side effects, has good health-care treatment.
Toothpaste is as requisite dental care products ordinary person's every day, and along with science and technology development, all kinds of toothpaste are asked in succession
Generation.The purposes of toothpaste does not the most terminate in oral cavity cleaning, may also be combined with Chinese medicine and pharmacy, by scientific composition, reaches other health cares
Effect.During daily brushing teeth, active component contained in toothpaste can be through sublingual vein, oral cavity blood capillary and mucosa
Infiltration, absorbed into serum, it is to avoid the first of active substance is closed elimination effect by the organs such as Liver and kidney, can reduce Liver and kidney burden simultaneously.
Early, evening brushes teeth becomes the custom of people, absorbs active ingredient of Chinese herbs, have side effect little, easy by the way of brushing teeth
The advantages such as acceptance, and can achieve many things at one stroke, get twice the result with half the effort.
Have Chinese medicine ingredients toothpaste at present and include that mica filled polypropylene, shiny pricklyash toothpaste etc., effect are mainly oral disease
Prevention and treatment.Chinese patent literature CN103083212A discloses a kind of red sage root toothpaste, and prescription includes: Radix Salviae Miltiorrhizae extracts
Thing, Radix Codonopsis extract, Folium Ginkgo extract, Folium Nelumbinis extract, Radix Polygoni Multiflori extract, Radix Curcumae extract etc.；This prescription
Mostly being the Chinese medicine ingredients with cardioprotection, its blood fat reducing function is more weak, and application has certain limitation.Chinese patent literary composition
Offer CN101112376A and disclose a kind of toothpaste for nursing cardiac and cerebral blood vessel with Radix Notoginseng as main component；This toothpaste component is to anti-
Controlling cardiovascular and cerebrovascular disease and have certain effect, but effective ingredient is single, effect is limited.It is thus desirable to scientific composition, from China
In huge Chinese material medicine resource reasonably combined, develop effect more preferable and the most nontoxic there is blood fat reducing, prevent and treat heart and brain
The Chinese medicinal toothpaste with health therapy function of angiopathy.
Summary of the invention
The present invention seeks to solve current Chinese medicinal toothpaste purposes single, lack the Chinese medicinal toothpaste with blood fat reducing function, and have
Toothpaste composition with the presence of preventing and treating cardiovascular and cerebrovascular disease effect is single, and lipid-lowering effect is more weak, it is impossible to reach long-term care treatment
The technical problem of hyperlipemia, and Chinese medicine blood fat reducing toothpaste and preparation method thereof is provided.
Chinese medicine blood fat reducing toothpaste, by weight by the toothpaste substrate of 70-95 part, the Herb Gynostemmae Pentaphylli extract of 1-10 part, 1-5 part
Rhizoma Polygoni Cuspidati extract, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe extract of 1-5 part and 1-5 part Radix Notoginseng extract composition；Its
Described in toothpaste with substrate by weight by the abrasivus of 12-60 part, the wetting agent of 5-60 part, the thickening agent of 0.5-4 part,
The foaming agent of 1-5.5 part, the spice of 0-2 part, the sweeting agent of 0-1 part, the food coloring of 0-1 part, the preservative of 0-0.5 part
Form with the deionized water of 6-33.5 part.
The method preparing above-mentioned Chinese medicine blood fat reducing toothpaste, sequentially includes the following steps:
One, the abrasivus of 12-60 part, the wetting agent of 5-60 part, the thickening agent of 0.5-4 part, 1-5.5 part are weighed by weight
Foaming agent, the spice of 0-2 part, the sweeting agent of 0-1 part, the food coloring of 0-1 part, the preservative of 0-0.5 part, 6-33.5
The deionized water of part, then mixes, it is thus achieved that toothpaste substrate；
Two, Herb Gynostemmae Pentaphylli, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe and Radix Notoginseng are pulverized after over cleaning respectively, carry out active component the most respectively
Extraction, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, Radix Polygoni Multiflori extract, Aloe extract and Radix Notoginseng extract；
Three, weigh the toothpaste substrate of 70-95 part by weight, the Herb Gynostemmae Pentaphylli extract of 1-10 part, the Rhizoma Polygoni Cuspidati of 1-5 part carry
Taking thing, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe extract of 1-5 part and the Radix Notoginseng extract of 1-5 part, mix homogeneously is placed on
In vacuum Manufacturing medicine extract machine, keep vacuum at-0.09MPa～-0.096MPa, carry out fill after homogenizing process stirs, i.e.
Complete the preparation of Chinese medicine blood fat reducing toothpaste；
Wherein said abrasivus is calcium phosphate dibasic anhydrous, dicalcium phosphate dehydrate, anhydride silica, anhydrous calcium pyrophosphate, carbon
Any combination of one or more in acid calcium, clinochlore powder, calcite in powder, aluminium hydroxide；
Wetting agent is any combination of one or more in glycerol, propylene glycol, glycerol, Polyethylene Glycol, sorbitol；
Thickening agent is sodium carboxymethyl cellulose, carbomer, carboxyethyl cellulose, hydroxypropyl melon glue, carrageenan, thickening
Any combination of one or more in type silicon dioxide, colloidality aluminium-magnesium silicate, sodium alginate, yellow natural gum powder；
Foaming agent is sodium lauryl sulphate, acyl glutamic acid sodium, sodium lauroyl sarcosine, methyl cocoa aliphatic radical sodium taurocholate
In any combination of one or more；
Spice is purple lemon sesame oil, orange oil, mandarin oil, Soviet Union's oil, Oleum Menthae Rotundifoliae, wintergreen oil, Oleum Caryophylli, Oleum Cinnamomi, fennel
Appointing of one or more in Oleum sesami, Oleum menthae, Mentholum, Borneolum Syntheticum, lauryl aldehyde, citral, vanillin, pentyl acetate
Meaning is than combination；
Sweeting agent is sucrose, saccharin, cyclamate, xylitol, stevioside, disodium glycyrrhizinate, tripotassium glycyrrhetate and glycyrrhizic acid
Any combination of one or more in trisodium；
Food coloring is purple, pink colour, blue or green；
Preservative be one or more in p-Hydroxybenzoate, sodium benzoate, potassium sorbate, sorbitol arbitrarily than group
Close.
Chinese medicine blood fat reducing toothpaste, by weight by the toothpaste substrate of 70-95 part, the Herb Gynostemmae Pentaphylli extract of 1-10 part, 1-5 part
The Radix Notoginseng extract composition of Rhizoma Polygoni Cuspidati extract, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe extract of 1-5 part and 1-5 part, also
Extract including the Rhizoma Alismatis extract of 1-2 part, the Radix Et Rhizoma Rhei extract of 1-2 part, the Rhizoma Curcumae Longae extract of 1-2 part, the Ganoderma of 1-2 part
Thing, the Semen Raphani extract of 1-2 part, the Herba Artemisiae Scopariae extract of 1-2 part, the Rhizoma Curcumae extract of 1-2 part, the Radix Curcumae of 1-2 part carry
Take thing, the Ramulus Cinnamomi extract of 1-2 part, the Rhizoma Atractylodis Macrocephalae extract of 1-2 part, the Fructus Sophorae extract of 1-2 part, the Radix Scrophulariae of 1-2 part carry
Take the red scape of thing, the Radix Paeoniae Rubra extract of 1-2 part, the Rhizoma Drynariae extract of 1-2 part, the Rhizoma Chuanxiong extract of 1-2 part, 1-2 part
It extract, the Rhizoma Fagopyri Dibotryis extract of 1-2 part, 1-2 part Radix Bupleuri extract in 1-3 kind；Wherein said toothpaste substrate
By weight by the abrasivus of 12-60 part, the wetting agent of 5-60 part, the thickening agent of 0.5-4 part, the foaming agent of 1-5.5 part,
The spice of 0-2 part, the sweeting agent of 0-1 part, the food coloring of 0-1 part, the preservative of 0-0.5 part and 6-33.5 part go from
Sub-water forms.
The method preparing above-mentioned Chinese medicine blood fat reducing toothpaste, sequentially includes the following steps:
One, the abrasivus of 12-60 part, the wetting agent of 5-60 part, the thickening agent of 0.5-4 part, 1-5.5 part are weighed by weight
Foaming agent, the spice of 0-2 part, the sweeting agent of 0-1 part, the food coloring of 0-1 part, the preservative of 0-0.5 part, 6-33.5
The deionized water of part, then mixes, it is thus achieved that toothpaste substrate；
Two, Herb Gynostemmae Pentaphylli, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe, Radix Notoginseng, Rhizoma Alismatis, Radix Et Rhizoma Rhei, Rhizoma Curcumae Longae, Ganoderma, Semen Raphani, Herba Artemisiae Scopariae,
Rhizoma Curcumae, Radix Curcumae, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, the Fructus Sophorae, Radix Scrophulariae, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Chuanxiong, Radix Rhodiolae, Rhizoma Fagopyri Dibotryis and Radix Bupleuri warp
Pulverize respectively after over cleaning, carry out the extraction of active component the most respectively, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, head
Crow extract, Aloe extract, Radix Notoginseng extract, Rhizoma Alismatis extract, Radix Et Rhizoma Rhei extract, Rhizoma Curcumae Longae extract, Ganoderma are extracted
Thing, Semen Raphani extract, Herba Artemisiae Scopariae extract, Rhizoma Curcumae extract, Radix Curcumae extract, Ramulus Cinnamomi extract, Rhizoma Atractylodis Macrocephalae extract,
Fructus Sophorae extract, Radix Scrophulariae extract, Radix Paeoniae Rubra extract, Rhizoma Drynariae extract, Rhizoma Chuanxiong extract, Radix Rhodiolae extract, gold
Semen Fagopyri Esculenti extract and Radix Bupleuri extract；
Three, weigh by weight the Rhizoma Alismatis extract of 1-2 part, the Radix Et Rhizoma Rhei extract of 1-2 part, the Rhizoma Curcumae Longae extract of 1-2 part,
The Ganoderma extract of 1-2 part, the Semen Raphani extract of 1-2 part, the Herba Artemisiae Scopariae extract of 1-2 part, the Rhizoma Curcumae extract of 1-2 part,
The Radix Curcumae extract of 1-2 part, the Ramulus Cinnamomi extract of 1-2 part, the Rhizoma Atractylodis Macrocephalae extract of 1-2 part, the Fructus Sophorae extract of 1-2 part,
The Radix Scrophulariae extract of 1-2 part, the Radix Paeoniae Rubra extract of 1-2 part, the Rhizoma Drynariae extract of 1-2 part, the Rhizoma Chuanxiong extract of 1-2 part,
The Radix Rhodiolae extract of 1-2 part, the Rhizoma Fagopyri Dibotryis extract of 1-2 part, 1-2 part Radix Bupleuri extract in 1-3 kind, then add
Enter the Herb Gynostemmae Pentaphylli extract of 1-10 part, the Rhizoma Polygoni Cuspidati extract of 1-5 part, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe of 1-5 part carry
Taking the toothpaste substrate of thing, the Radix Notoginseng extract of 1-5 part and 70-95 part, mix homogeneously is placed in vacuum Manufacturing medicine extract machine, protects
Hold vacuum at-0.09MPa～-0.096MPa, carry out homogenizing process stir after fill, i.e. complete Chinese medicine blood fat reducing toothpaste
Preparation；
Wherein said abrasivus is calcium phosphate dibasic anhydrous, dicalcium phosphate dehydrate, anhydride silica, anhydrous calcium pyrophosphate, carbon
Any combination of one or more in acid calcium, clinochlore powder, calcite in powder, aluminium hydroxide；
Wetting agent is any combination of one or more in glycerol, propylene glycol, glycerol, Polyethylene Glycol, sorbitol；
Thickening agent is sodium carboxymethyl cellulose, carbomer, carboxyethyl cellulose, hydroxypropyl melon glue, carrageenan, thickening
Any combination of one or more in type silicon dioxide, colloidality aluminium-magnesium silicate, sodium alginate, yellow natural gum powder；
Foaming agent is sodium lauryl sulphate, acyl glutamic acid sodium, sodium lauroyl sarcosine, methyl cocoa aliphatic radical sodium taurocholate
In any combination of one or more；
Spice is purple lemon sesame oil, orange oil, mandarin oil, Soviet Union's oil, Oleum Menthae Rotundifoliae, wintergreen oil, Oleum Caryophylli, Oleum Cinnamomi, fennel
Appointing of one or more in Oleum sesami, Oleum menthae, Mentholum, Borneolum Syntheticum, lauryl aldehyde, citral, vanillin, pentyl acetate
Meaning is than combination；
Sweeting agent is sucrose, saccharin, cyclamate, xylitol, stevioside, disodium glycyrrhizinate, tripotassium glycyrrhetate and glycyrrhizic acid
Any combination of one or more in trisodium；
Food coloring is purple, pink colour, blue or green；
Preservative be one or more in p-Hydroxybenzoate, sodium benzoate, potassium sorbate, sorbitol arbitrarily than group
Close.
In the raw material of Chinese medicine blood fat reducing toothpaste of the present invention, the selected main active ingredient of Herb Gynostemmae Pentaphylli is gypenoside, Herb Gynostemmae Pentaphylli glucoside
(polysaccharide), water-soluble amino acid, flavonoid, multivitamin, trace element, mineral etc., have eliminating inflammation and expelling toxin, cough-relieving
The effect eliminated the phlegm, also can treat the diseases such as hypertension, hyperlipidemia, hyperglycemia, fatty liver.Rhizoma Polygoni Cuspidati has dampness removing jaundice eliminating, heat clearing away
Removing toxic substances, eliminating stasis to stop pain, effect of relieving cough and resolving phlegm, can be used for antitussive, Adjust-blood lipid, reduction cholesterol, shock.The Radix Polygoni Multiflori can
Reduce total plasma cholesterol, triglyceride, free cholesterol and cholesteryl ester, delay the atherosis formation and development that beats one's brains.
Aloe can blood circulation promoting, reduce cholesterol level, treat hyperlipemia, hypercholesterolemia.Radix Notoginseng property hardship sweet, micro-,
Temperature, have dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain, can hemostasia and dissipation blood stasis, expand blood vessel, reduce blood pressure, blood fat reducing, improve
Blood microcirculation, increases blood flow.Above five kinds of Chinese medicines are respectively provided with good Antilipemic health effect.
For increasing effect of above-mentioned herbaceous plant formula, Chinese medicinal toothpaste of the present invention is also alternative adds 1-3 kind Rhizoma Alismatis,
Radix Et Rhizoma Rhei, Rhizoma Curcumae Longae, Ganoderma, Semen Raphani, Herba Artemisiae Scopariae, Rhizoma Curcumae, Radix Curcumae, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, the Fructus Sophorae, Radix Scrophulariae, Radix Paeoniae Rubra, osteomiosis
Mend, Rhizoma Chuanxiong, Radix Rhodiolae, Rhizoma Fagopyri Dibotryis, Radix Bupleuri.
Rhizoma Alismatis nature and flavor are sweet salty-cold, return kidney, bladder two warp, are mainly composed of volatile oil, and extract has blood fat reducing anti-fatty liver to become
Point.Radix Et Rhizoma Rhei nature and flavor bitter cold, returns spleen, stomach, large intestine, liver, the pericardium Five Classics, and this medical instrument has purging heat to relax the bowels, removing mass blood stasis expelling, clear
The function such as damp and hot, Radix Et Rhizoma Rhei can cause intestinal contraction, secretion to increase and produce discharge function, and Radix Et Rhizoma Rhei has blood pressure lowering, cholesterol reducing
Effect.Rhizoma Curcumae Longae bitter in the mouth is pungent, warm in nature, returns liver, spleen two warp, and main component contains volatile oil, can declare the gas in logical blood, make gas row
And blood is not stopped up stagnant, can increase bile and be formed and secretion, make the cholic acid of excretion in feces and cholesterol increase, Rhizoma Curcumae Longae can also increase
Fibrinous dissolving activity, has antithrombotic effect.Ganoderma is warm in nature, slightly sweet flavor, Ganoderma containing sterol, alkaloid,
Protein, polysaccharide etc., have effect of beneficial vital essence, bone and muscle strengthening, cures mainly metal fatigue, palpitation and insomnia, hypertension, high gallbladder
Sterin mass formed by blood stasis, cerebrovascular sclerosis etc..Semen Raphani acrid-sweet flavor, can promoting the circulation of QI dissipating depression of QI, it is turbid to dispel expectorant, adjusts internal organs function, improves
Organism metabolism, promotes lipid material to drain, and accelerates cholesterol in serum and the removing of triglyceride.Herba Artemisiae Scopariae clearing away heat-damp and promoting diuresis, moves back
Huang, cures mainly jaundice, dysuria, eczema pruritus, infectious jaundice type hepatitis etc., and pharmaceutical research has function of gallbladder promoting, protects liver
Function, antipyretic, antiinflammatory, blood fat reducing, blood pressure lowering, coronary dilating etc. acts on.Rhizoma Curcumae can control promoting the circulation of QI to relieve pain, long-pending eliminating stagnation, removing blood stasis,
There is heat clearing away, removing toxic substances, turbid effect of dispelling, hinders the hyperlipemia caused for phlegm-turbidity and blood stasis.Radix Curcumae has promoting blood circulation to relieve pain, circulation of qi promoting solution
Strongly fragrant, clear away heart-fire removing heat from blood, and the effect of depressed liver-energy dispersing and function of gallbladder promoting also has regulation immunity, improves blood circulation, the merit of free radical resisting damage
Effect, Radix Curcumae can reduce serum cholesterol and apolipoprotein B, prevents blood vessel wall lipid accumulation.Ramulus Cinnamomi belongs to pungent and warm medicine for relieving the exterior syndrome,
There is the effect of dispelling cold by warming the meridian, blood microcirculation pipe, pre-anti-aging, blood pressure lowering, blood fat reducing, blood sugar lowering, anticancer can be improved.The Rhizoma Atractylodis Macrocephalae is not
Only can damp eliminating dampness removing, moreover it is possible to spleen invigorating, blood fat reducing, blood sugar lowering.The Fructus Sophorae has vessel softening, blood pressure lowering, cholesterol reducing, dispelling wind
Heat, moistens large intestine, effect of removing heat from blood relieving constipation.Radix Scrophulariae can be used for treating the blood caused due to hyperlipemia and is obstructed, and blood is sticky
Degree height.Radix Paeoniae Rubra can clots absorbing, pain relieving, removing heat from blood, detumescence, cure mainly the stagnant amenorrhea of the stasis of blood, the accumulation of hernia abdominal mass, stomachache, there is significantly fall
Fat, anti peroxidation of lipid, the effect of degraded plasma fibrinogen.Rhizoma Drynariae has prevention blood fat to raise and treatment hyperlipemia
Effect, and the formation of Aorta atheromatous plague can be prevented.Rhizoma Chuanxiong has the effect of blood circulation promoting competent silt, it is possible to decrease blood viscosity,
Cholesterol and triglyceride.Radix Rhodiolae can effectively facilitate cholesterol and the metabolism of fat so that it is is not deposited on blood vessel, from
And reduce blood fat and blood viscosity, reduce the formation of thrombosis.It is little that Rhizoma Fagopyri Dibotryis has blood lipid-reducing blood sugar-decreasing, eliminating phlegm and relieving cough and suppression blood
Plate gatherings etc. act on.Radix Bupleuri has a hepatic cholagogic, reduces cholesterolemia and the effect of triglyceride, can treat hyperlipemia and
Atherosclerosis.Above Chinese herbal medicine Bloodlipid-lowering is definite, and toxicity is low, few side effects, has good health-care treatment.
Above herbaceous plant is respectively provided with good Antilipemic health effect.
The herbaceous plant active component added in Chinese medicine blood fat reducing toothpaste of the present invention, is to form according to Chinese medical theory scientific compatibility,
There is heat clearing and damp drying, reducing weight and blood fat, reducing pressure and sugar, reduction serum cholesterol, effect of triglyceride, also can antihalitosis,
Treatment dental bed swells and ache, words raw skin ulcer, toothache due to dental caries.By morning every day, brushing teeth evening, active component is through sublingual vein, oral cavity
Blood capillary and mucosa penetration, absorbed into serum, it is to avoid the first pass elimination effect to active ingredient of Chinese herbs of the organs such as Liver and kidney, simultaneously
Liver and kidney burden can be alleviated.Chinese medicine blood fat reducing toothpaste of the present invention is in addition to having traditional oral cavity cleaning effect, and active component also can reduce
T-CHOL, triglyceride, low density lipoprotein, LDL, to the cardiovascular and cerebrovascular vessel such as hyperlipemia, hypercholesterolemia and metabolic disease
Disease has good health protection and therapeutic action.
The preparation method of Chinese medicine blood fat reducing toothpaste of the present invention, technique is simple, and raw material is easy to get, and is suitable for large-scale production.
Detailed description of the invention
Technical solution of the present invention is not limited to act detailed description of the invention set forth below, also includes appointing between each detailed description of the invention
Meaning combination.
Detailed description of the invention one: present embodiment Chinese medicine blood fat reducing toothpaste, by weight by the toothpaste substrate of 70-95 part, 1-10
Herb Gynostemmae Pentaphylli extract, the Rhizoma Polygoni Cuspidati extract of 1-5 part, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe extract of 1-5 part and the 1-5 of part
The Radix Notoginseng extract composition of part；Wherein said toothpaste substrate is by weight by the abrasivus of 12-60 part, the moisturizing of 5-60 part
Agent, the thickening agent of 0.5-4 part, the foaming agent of 1-5.5 part, the spice of 0-2 part, the sweeting agent of 0-1 part, 0-1 part edible
The deionized water composition of pigment, the preservative of 0-0.5 part and 6-33.5 part.
Detailed description of the invention two: present embodiment is unlike detailed description of the invention one: described Chinese medicine blood fat reducing toothpaste, presses
Weight portion is extracted by the toothpaste substrate of 80 parts, the Herb Gynostemmae Pentaphylli extract of 8 parts, the Rhizoma Polygoni Cuspidati extract of 3 parts, the Radix Polygoni Multiflori of 3 parts
The Radix Notoginseng extract composition of thing, the Aloe extract of 3 parts and 3 parts.Other is identical with detailed description of the invention one.
Detailed description of the invention three: present embodiment is unlike detailed description of the invention one: described toothpaste substrate is by weight
Part is by the deionized water group of the abrasivus of 50 parts, the wetting agent of 10 parts, the thickening agent of 3 parts, the foaming agent of 5 parts and 32 parts
Become.Other is identical with detailed description of the invention one.
Detailed description of the invention four: present embodiment is unlike detailed description of the invention one: described toothpaste substrate is by weight
Part by the abrasivus of 48 parts, the wetting agent of 20 parts, the thickening agent of 2 parts, the foaming agent of 4 parts, the spice of 1 part, 0.5 part
Sweeting agent, the food coloring of 0.2 part, the preservative of 0.1 part and 24.2 parts deionized water composition.Other is real with concrete
Execute mode one identical.
Detailed description of the invention five: the preparation method of present embodiment above-mentioned Chinese medicine blood fat reducing toothpaste, sequentially includes the following steps:
One, the abrasivus of 12-60 part, the wetting agent of 5-60 part, the thickening agent of 0.5-4 part, 1-5.5 part are weighed by weight
Foaming agent, the spice of 0-2 part, the sweeting agent of 0-1 part, the food coloring of 0-1 part, the preservative of 0-0.5 part, 6-33.5
The deionized water of part, then mixes, it is thus achieved that toothpaste substrate；
Two, Herb Gynostemmae Pentaphylli, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe and Radix Notoginseng are pulverized after over cleaning respectively, carry out active component the most respectively
Extraction, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, Radix Polygoni Multiflori extract, Aloe extract and Radix Notoginseng extract；
Three, weigh the toothpaste substrate of 70-95 part by weight, the Herb Gynostemmae Pentaphylli extract of 1-10 part, the Rhizoma Polygoni Cuspidati of 1-5 part carry
Taking thing, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe extract of 1-5 part and the Radix Notoginseng extract of 1-5 part, mix homogeneously is placed on
In vacuum Manufacturing medicine extract machine, keep vacuum at-0.09MPa～-0.096MPa, carry out fill after homogenizing process stirs, i.e.
Complete the preparation of Chinese medicine blood fat reducing toothpaste；
Wherein said abrasivus is calcium phosphate dibasic anhydrous, dicalcium phosphate dehydrate, anhydride silica, anhydrous calcium pyrophosphate, carbon
Any combination of one or more in acid calcium, clinochlore powder, calcite in powder, aluminium hydroxide；
Wetting agent is any combination of one or more in glycerol, propylene glycol, glycerol, Polyethylene Glycol, sorbitol；
Thickening agent is sodium carboxymethyl cellulose, carbomer, carboxyethyl cellulose, hydroxypropyl melon glue, carrageenan, thickening
Any combination of one or more in type silicon dioxide, colloidality aluminium-magnesium silicate, sodium alginate, yellow natural gum powder；
Foaming agent is sodium lauryl sulphate, acyl glutamic acid sodium, sodium lauroyl sarcosine, methyl cocoa aliphatic radical sodium taurocholate
In any combination of one or more；
Spice is purple lemon sesame oil, orange oil, mandarin oil, Soviet Union's oil, Oleum Menthae Rotundifoliae, wintergreen oil, Oleum Caryophylli, Oleum Cinnamomi, fennel
Appointing of one or more in Oleum sesami, Oleum menthae, Mentholum, Borneolum Syntheticum, lauryl aldehyde, citral, vanillin, pentyl acetate
Meaning is than combination；
Sweeting agent is sucrose, saccharin, cyclamate, xylitol, stevioside, disodium glycyrrhizinate, tripotassium glycyrrhetate and glycyrrhizic acid
Any combination of one or more in trisodium；
Food coloring is purple, pink colour, blue or green；
Preservative be one or more in p-Hydroxybenzoate, sodium benzoate, potassium sorbate, sorbitol arbitrarily than group
Close.
In present embodiment, the raw material of toothpaste substrate all can directly be bought from market.
Present embodiment Chinese medicine blood fat reducing toothpaste according to fragrance component can be prepared as mint aroma, Herba Menthae Rotundifoliae type, Ilicis Purpureae odor type,
Fruit flavouring, tea are felt well odor type, medicine odor type etc..
Detailed description of the invention six: present embodiment is unlike detailed description of the invention five: in step 2, active component carries
Take as follows: Herb Gynostemmae Pentaphylli, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe and the Radix Notoginseng after pulverizing, add 8 respectively～the deionized water of 16 times of volumes
Decoct 2 times, each 1h, the extracting solution every time decocting gained is filtered, and with activated carbon decolorizing, all concentrate as proportion
The extractum of 1.10-1.30, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, Radix Polygoni Multiflori extract, Aloe extract and Radix Notoginseng carry
Take thing.Other step and parameter are identical with detailed description of the invention five.
The relative density of the extractum of present embodiment proportion 1.10-1.30 be 40～60 DEG C under conditions of close relative to water of clear paste
Degree.
Detailed description of the invention seven: present embodiment is unlike detailed description of the invention five: in step 2, active component carries
Taking can also be as follows: Herb Gynostemmae Pentaphylli, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe and the Radix Notoginseng after pulverizing, adds 8 respectively～the matter of 16 times of volumes
Amount concentration is the alcohol reflux 3 times of 70%, each 2h, and the extracting solution that will every time decoct gained filters, and with active
Carbon decoloring, all concentrates as the extractum of proportion 1.10-1.30, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, Radix Polygoni Multiflori extract,
Aloe extract and Radix Notoginseng extract.Other step and parameter are identical with detailed description of the invention five.
Detailed description of the invention eight: present embodiment Chinese medicine blood fat reducing toothpaste, by weight by the toothpaste substrate of 70-95 part, 1-10
Herb Gynostemmae Pentaphylli extract, the Rhizoma Polygoni Cuspidati extract of 1-5 part, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe extract of 1-5 part and the 1-5 of part
The Radix Notoginseng extract composition of part, also includes that the Rhizoma Alismatis extract of 1-2 part, the Radix Et Rhizoma Rhei extract of 1-2 part, the Rhizoma Curcumae Longae of 1-2 part carry
Take thing, the Ganoderma extract of 1-2 part, the Semen Raphani extract of 1-2 part, the Herba Artemisiae Scopariae extract of 1-2 part, the Rhizoma Curcumae of 1-2 part
Extract, the Radix Curcumae extract of 1-2 part, the Ramulus Cinnamomi extract of 1-2 part, the Rhizoma Atractylodis Macrocephalae extract of 1-2 part, the Fructus Sophorae of 1-2 part
Extract, the Radix Scrophulariae extract of 1-2 part, the Radix Paeoniae Rubra extract of 1-2 part, the Rhizoma Drynariae extract of 1-2 part, the river of 1-2 part
Rhizome of chuanxiong extract, the Radix Rhodiolae extract of 1-2 part, the Rhizoma Fagopyri Dibotryis extract of 1-2 part, 1-2 part Radix Bupleuri extract in 1-3
Kind；Wherein said toothpaste substrate is by weight by the abrasivus of 12-60 part, the wetting agent of 5-60 part, the increasing of 0.5-4 part
Thick dose, the foaming agent of 1-5.5 part, the spice of 0-2 part, the sweeting agent of 0-1 part, the food coloring of 0-1 part, 0-0.5 part
The deionized water composition of preservative and 6-33.5 part.
Detailed description of the invention nine: present embodiment is unlike detailed description of the invention eight: described Chinese medicine blood fat reducing toothpaste, presses
Weight portion is extracted by the toothpaste substrate of 80 parts, the Herb Gynostemmae Pentaphylli extract of 2 parts, the Rhizoma Polygoni Cuspidati extract of 2 parts, the Radix Polygoni Multiflori of 2 parts
The Radix Notoginseng extract composition of thing, the Aloe extract of 2 parts and 2 parts, also includes the Rhizoma Alismatis extract of 1 part, the Radix Et Rhizoma Rhei of 1 part
Extract, the Rhizoma Curcumae Longae extract of 1 part.Other is identical with detailed description of the invention eight.
Detailed description of the invention ten: present embodiment is unlike detailed description of the invention eight: described Chinese medicine blood fat reducing toothpaste, presses
Weight portion is extracted by the toothpaste substrate of 85 parts, the Herb Gynostemmae Pentaphylli extract of 3 parts, the Rhizoma Polygoni Cuspidati extract of 3 parts, the Radix Polygoni Multiflori of 3 parts
The Radix Notoginseng extract composition of thing, the Aloe extract of 1 part and 1 part, also includes the Ganoderma extract of 2 parts, the Radix Raphani of 2 parts
Seed extract.Other step and parameter are identical with detailed description of the invention eight.
Detailed description of the invention 11: present embodiment is unlike detailed description of the invention eight: described Chinese medicine blood fat reducing toothpaste,
Carried by the toothpaste substrate of 90 parts, the Herb Gynostemmae Pentaphylli extract of 2 parts, the Rhizoma Polygoni Cuspidati extract of 2 parts, the Radix Polygoni Multiflori of 1 part by weight
Take the Radix Notoginseng extract composition of thing, the Aloe extract of 1 part and 2 parts, also include the Radix Scrophulariae extract of 2 parts.Other step
And parameter is identical with detailed description of the invention eight.
Detailed description of the invention 11: the preparation method of present embodiment above-mentioned Chinese medicine blood fat reducing toothpaste, sequentially includes the following steps:
One, the abrasivus of 12-60 part, the wetting agent of 5-60 part, the thickening agent of 0.5-4 part, 1-5.5 part are weighed by weight
Foaming agent, the spice of 0-2 part, the sweeting agent of 0-1 part, the food coloring of 0-1 part, the preservative of 0-0.5 part, 6-33.5
The deionized water of part, then mixes, it is thus achieved that toothpaste substrate；
Two, Herb Gynostemmae Pentaphylli, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe, Radix Notoginseng, Rhizoma Alismatis, Radix Et Rhizoma Rhei, Rhizoma Curcumae Longae, Ganoderma, Semen Raphani, Herba Artemisiae Scopariae,
Rhizoma Curcumae, Radix Curcumae, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, the Fructus Sophorae, Radix Scrophulariae, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Chuanxiong, Radix Rhodiolae, Rhizoma Fagopyri Dibotryis and Radix Bupleuri warp
Pulverize respectively after over cleaning, carry out the extraction of active component the most respectively, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, head
Crow extract, Aloe extract, Radix Notoginseng extract, Rhizoma Alismatis extract, Radix Et Rhizoma Rhei extract, Rhizoma Curcumae Longae extract, Ganoderma are extracted
Thing, Semen Raphani extract, Herba Artemisiae Scopariae extract, Rhizoma Curcumae extract, Radix Curcumae extract, Ramulus Cinnamomi extract, Rhizoma Atractylodis Macrocephalae extract,
Fructus Sophorae extract, Radix Scrophulariae extract, Radix Paeoniae Rubra extract, Rhizoma Drynariae extract, Rhizoma Chuanxiong extract, Radix Rhodiolae extract, gold
Semen Fagopyri Esculenti extract and Radix Bupleuri extract；
Three, weigh by weight the Rhizoma Alismatis extract of 1-2 part, the Radix Et Rhizoma Rhei extract of 1-2 part, the Rhizoma Curcumae Longae extract of 1-2 part,
The Ganoderma extract of 1-2 part, the Semen Raphani extract of 1-2 part, the Herba Artemisiae Scopariae extract of 1-2 part, the Rhizoma Curcumae extract of 1-2 part,
The Radix Curcumae extract of 1-2 part, the Ramulus Cinnamomi extract of 1-2 part, the Rhizoma Atractylodis Macrocephalae extract of 1-2 part, the Fructus Sophorae extract of 1-2 part,
The Radix Scrophulariae extract of 1-2 part, the Radix Paeoniae Rubra extract of 1-2 part, the Rhizoma Drynariae extract of 1-2 part, the Rhizoma Chuanxiong extract of 1-2 part,
The Radix Rhodiolae extract of 1-2 part, the Rhizoma Fagopyri Dibotryis extract of 1-2 part, 1-2 part Radix Bupleuri extract in 1-3 kind, then add
Enter the Herb Gynostemmae Pentaphylli extract of 1-10 part, the Rhizoma Polygoni Cuspidati extract of 1-5 part, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe of 1-5 part carry
Taking the toothpaste substrate of thing, the Radix Notoginseng extract of 1-5 part and 70-95 part, mix homogeneously is placed in vacuum Manufacturing medicine extract machine, protects
Hold vacuum at-0.09MPa～-0.096MPa, carry out homogenizing process stir after fill, i.e. complete Chinese medicine blood fat reducing toothpaste
Preparation；
Wherein said abrasivus is calcium phosphate dibasic anhydrous, dicalcium phosphate dehydrate, anhydride silica, anhydrous calcium pyrophosphate, carbon
Any combination of one or more in acid calcium, clinochlore powder, calcite in powder, aluminium hydroxide；
Wetting agent is any combination of one or more in glycerol, propylene glycol, glycerol, Polyethylene Glycol, sorbitol；
Thickening agent is sodium carboxymethyl cellulose, carbomer, carboxyethyl cellulose, hydroxypropyl melon glue, carrageenan, thickening
Any combination of one or more in type silicon dioxide, colloidality aluminium-magnesium silicate, sodium alginate, yellow natural gum powder；
Foaming agent is sodium lauryl sulphate, acyl glutamic acid sodium, sodium lauroyl sarcosine, methyl cocoa aliphatic radical sodium taurocholate
In any combination of one or more；
Spice is purple lemon sesame oil, orange oil, mandarin oil, Soviet Union's oil, Oleum Menthae Rotundifoliae, wintergreen oil, Oleum Caryophylli, Oleum Cinnamomi, fennel
Appointing of one or more in Oleum sesami, Oleum menthae, Mentholum, Borneolum Syntheticum, lauryl aldehyde, citral, vanillin, pentyl acetate
Meaning is than combination；
Sweeting agent is sucrose, saccharin, cyclamate, xylitol, stevioside, disodium glycyrrhizinate, tripotassium glycyrrhetate and glycyrrhizic acid
Any combination of one or more in trisodium；
Food coloring is purple, pink colour, blue or green；
Preservative be one or more in p-Hydroxybenzoate, sodium benzoate, potassium sorbate, sorbitol arbitrarily than
Combination.
Detailed description of the invention 12: present embodiment is unlike detailed description of the invention 11: active component in step 2
Extraction as follows: the Herb Gynostemmae Pentaphylli after pulverizing, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe, Radix Notoginseng, Rhizoma Alismatis, Radix Et Rhizoma Rhei, Rhizoma Curcumae Longae, Ganoderma, Lay
Fu, Herba Artemisiae Scopariae, Rhizoma Curcumae, Radix Curcumae, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, the Fructus Sophorae, Radix Scrophulariae, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Chuanxiong, Radix Rhodiolae, gold
Semen Fagopyri Esculenti and Radix Bupleuri, add 8 respectively～the deionized water of 16 times of volumes decocts 2 times, each 1h, will decoct carrying of gained every time
Take liquid to filter, and with activated carbon decolorizing, all concentrate the extractum for proportion 1.10-1.30, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati
Extract, Radix Polygoni Multiflori extract, Aloe extract, Radix Notoginseng extract, Rhizoma Alismatis extract, Radix Et Rhizoma Rhei extract, Rhizoma Curcumae Longae extract,
Ganoderma extract, Semen Raphani extract, Herba Artemisiae Scopariae extract, Rhizoma Curcumae extract, Radix Curcumae extract, Ramulus Cinnamomi extract, the Rhizoma Atractylodis Macrocephalae
Extract, Fructus Sophorae extract, Radix Scrophulariae extract, Radix Paeoniae Rubra extract, Rhizoma Drynariae extract, Rhizoma Chuanxiong extract, Radix Rhodiolae carry
Take thing, Rhizoma Fagopyri Dibotryis extract and Radix Bupleuri extract.Other step and parameter are identical with detailed description of the invention 11.
The relative density of the extractum of present embodiment proportion 1.10-1.30 be 40～60 DEG C under conditions of close relative to water of clear paste
Degree.
Detailed description of the invention 13: present embodiment is unlike detailed description of the invention 11: active component in step 2
Extraction can also be as follows: the Herb Gynostemmae Pentaphylli after pulverizing, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe, Radix Notoginseng, Rhizoma Alismatis, Radix Et Rhizoma Rhei, Rhizoma Curcumae Longae, spirit
Sesame, Semen Raphani, Herba Artemisiae Scopariae, Rhizoma Curcumae, Radix Curcumae, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, the Fructus Sophorae, Radix Scrophulariae, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Chuanxiong, red scape
My god, Rhizoma Fagopyri Dibotryis and Radix Bupleuri, add 8 respectively～alcohol reflux that the mass concentration of 16 times of volumes is 70% 3 times, every time
2h, filters the extracting solution decocting gained every time, and with activated carbon decolorizing, all concentrates the extractum for proportion 1.10-1.30,
Obtain Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, Radix Polygoni Multiflori extract, Aloe extract, Radix Notoginseng extract, Rhizoma Alismatis extract,
Radix Et Rhizoma Rhei extract, Rhizoma Curcumae Longae extract, Ganoderma extract, Semen Raphani extract, Herba Artemisiae Scopariae extract, Rhizoma Curcumae extract, Radix Curcumae
Extract, Ramulus Cinnamomi extract, Rhizoma Atractylodis Macrocephalae extract, Fructus Sophorae extract, Radix Scrophulariae extract, Radix Paeoniae Rubra extract, Rhizoma Drynariae extract
Thing, Rhizoma Chuanxiong extract, Radix Rhodiolae extract, Rhizoma Fagopyri Dibotryis extract and Radix Bupleuri extract.Other step and parameter are real with concrete
Execute mode 11 identical.
Employing following example checking beneficial effects of the present invention:
The preparation method of Chinese medicine blood fat reducing toothpaste, sequentially includes the following steps:
One, the abrasivus of 12-60 part, the wetting agent of 5-60 part, the thickening agent of 0.5-4 part, 1-5.5 part are weighed by weight
Foaming agent, the spice of 0-2 part, the sweeting agent of 0-1 part, the food coloring of 0-1 part, the preservative of 0-0.5 part, 6-33.5
The deionized water of part, then mixes, it is thus achieved that toothpaste substrate；
Two, Herb Gynostemmae Pentaphylli, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe, Radix Notoginseng, Rhizoma Alismatis, Radix Et Rhizoma Rhei, Rhizoma Curcumae Longae, Ganoderma, Semen Raphani, Herba Artemisiae Scopariae,
Rhizoma Curcumae, Radix Curcumae, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, the Fructus Sophorae, Radix Scrophulariae, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Chuanxiong, Radix Rhodiolae, Rhizoma Fagopyri Dibotryis and Radix Bupleuri warp
Pulverize respectively after over cleaning, carry out the extraction of active component the most respectively, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, head
Crow extract, Aloe extract, Radix Notoginseng extract, Rhizoma Alismatis extract, Radix Et Rhizoma Rhei extract, Rhizoma Curcumae Longae extract, Ganoderma are extracted
Thing, Semen Raphani extract, Herba Artemisiae Scopariae extract, Rhizoma Curcumae extract, Radix Curcumae extract, Ramulus Cinnamomi extract, Rhizoma Atractylodis Macrocephalae extract,
Fructus Sophorae extract, Radix Scrophulariae extract, Radix Paeoniae Rubra extract, Rhizoma Drynariae extract, Rhizoma Chuanxiong extract, Radix Rhodiolae extract, gold
Semen Fagopyri Esculenti extract and Radix Bupleuri extract；
Three, weigh by weight the Rhizoma Alismatis extract of 1-2 part, the Radix Et Rhizoma Rhei extract of 1-2 part, the Rhizoma Curcumae Longae extract of 1-2 part,
The Ganoderma extract of 1-2 part, the Semen Raphani extract of 1-2 part, the Herba Artemisiae Scopariae extract of 1-2 part, the Rhizoma Curcumae extract of 1-2 part,
The Radix Curcumae extract of 1-2 part, the Ramulus Cinnamomi extract of 1-2 part, the Rhizoma Atractylodis Macrocephalae extract of 1-2 part, the Fructus Sophorae extract of 1-2 part,
The Radix Scrophulariae extract of 1-2 part, the Radix Paeoniae Rubra extract of 1-2 part, the Rhizoma Drynariae extract of 1-2 part, the Rhizoma Chuanxiong extract of 1-2 part,
The Radix Rhodiolae extract of 1-2 part, the Rhizoma Fagopyri Dibotryis extract of 1-2 part, 1-2 part Radix Bupleuri extract in 1-3 kind, then add
Enter the Herb Gynostemmae Pentaphylli extract of 1-10 part, the Rhizoma Polygoni Cuspidati extract of 1-5 part, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe of 1-5 part carry
Taking the toothpaste substrate of thing, the Radix Notoginseng extract of 1-5 part and 70-95 part, mix homogeneously is placed in vacuum Manufacturing medicine extract machine, protects
Hold vacuum at-0.09MPa, carry out homogenizing process stir after fill, i.e. complete the preparation of Chinese medicine blood fat reducing toothpaste；
Wherein said abrasivus is calcium phosphate dibasic anhydrous, dicalcium phosphate dehydrate, anhydride silica, anhydrous calcium pyrophosphate, carbon
Any combination of one or more in acid calcium, clinochlore powder, calcite in powder, aluminium hydroxide；
Wetting agent is any combination of one or more in glycerol, propylene glycol, glycerol, Polyethylene Glycol, sorbitol；
Thickening agent is sodium carboxymethyl cellulose, carbomer, carboxyethyl cellulose, hydroxypropyl melon glue, carrageenan, thickening
Any combination of one or more in type silicon dioxide, colloidality aluminium-magnesium silicate, sodium alginate, yellow natural gum powder；
Foaming agent is sodium lauryl sulphate, acyl glutamic acid sodium, sodium lauroyl sarcosine, methyl cocoa aliphatic radical sodium taurocholate
In any combination of one or more；
Spice is purple lemon sesame oil, orange oil, mandarin oil, Soviet Union's oil, Oleum Menthae Rotundifoliae, wintergreen oil, Oleum Caryophylli, Oleum Cinnamomi, fennel
Appointing of one or more in Oleum sesami, Oleum menthae, Mentholum, Borneolum Syntheticum, lauryl aldehyde, citral, vanillin, pentyl acetate
Meaning is than combination；
Sweeting agent is sucrose, saccharin, cyclamate, xylitol, stevioside, disodium glycyrrhizinate, tripotassium glycyrrhetate and glycyrrhizic acid
Any combination of one or more in trisodium；
Food coloring is purple, pink colour, blue or green；
Preservative be one or more in p-Hydroxybenzoate, sodium benzoate, potassium sorbate, sorbitol arbitrarily than group
Close.
In the present embodiment step 2, the extraction of active component is as follows: Herb Gynostemmae Pentaphylli after pulverizing, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe, Radix Notoginseng,
Rhizoma Alismatis, Radix Et Rhizoma Rhei, Rhizoma Curcumae Longae, Ganoderma, Semen Raphani, Herba Artemisiae Scopariae, Rhizoma Curcumae, Radix Curcumae, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, the Fructus Sophorae, Radix Scrophulariae, Radix Paeoniae Rubra,
Rhizoma Drynariae, Rhizoma Chuanxiong, Radix Rhodiolae, Rhizoma Fagopyri Dibotryis and Radix Bupleuri, add respectively 10 times of volumes deionized water decoct 2 times, every time
1h, filters the extracting solution decocting gained every time, and with activated carbon decolorizing, all concentrates the extractum for proportion 1.10-1.30,
Obtain Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, Radix Polygoni Multiflori extract, Aloe extract, Radix Notoginseng extract, Rhizoma Alismatis extract,
Radix Et Rhizoma Rhei extract, Rhizoma Curcumae Longae extract, Ganoderma extract, Semen Raphani extract, Herba Artemisiae Scopariae extract, Rhizoma Curcumae extract, Radix Curcumae
Extract, Ramulus Cinnamomi extract, Rhizoma Atractylodis Macrocephalae extract, Fructus Sophorae extract, Radix Scrophulariae extract, Radix Paeoniae Rubra extract, Rhizoma Drynariae extract
Thing, Rhizoma Chuanxiong extract, Radix Rhodiolae extract, Rhizoma Fagopyri Dibotryis extract and Radix Bupleuri extract.
In the present embodiment step 2, the extraction of active component can also be as follows: Herb Gynostemmae Pentaphylli after pulverizing, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe,
Radix Notoginseng, Rhizoma Alismatis, Radix Et Rhizoma Rhei, Rhizoma Curcumae Longae, Ganoderma, Semen Raphani, Herba Artemisiae Scopariae, Rhizoma Curcumae, Radix Curcumae, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, the Fructus Sophorae, Radix Scrophulariae,
Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Chuanxiong, Radix Rhodiolae, Rhizoma Fagopyri Dibotryis and Radix Bupleuri, the mass concentration adding 12 times of volumes respectively is 70%
Alcohol reflux 3 times, each 2h, filters the extracting solution decocting gained every time, and with activated carbon decolorizing, all concentrates
Extractum for proportion 1.10-1.30, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, Radix Polygoni Multiflori extract, Aloe extract,
Radix Notoginseng extract, Rhizoma Alismatis extract, Radix Et Rhizoma Rhei extract, Rhizoma Curcumae Longae extract, Ganoderma extract, Semen Raphani extract, Herba Artemisiae Scopariae
Extract, Rhizoma Curcumae extract, Radix Curcumae extract, Ramulus Cinnamomi extract, Rhizoma Atractylodis Macrocephalae extract, Fructus Sophorae extract, Radix Scrophulariae extract,
Radix Paeoniae Rubra extract, Rhizoma Drynariae extract, Rhizoma Chuanxiong extract, Radix Rhodiolae extract, Rhizoma Fagopyri Dibotryis extract and Radix Bupleuri extract
Embodiment 1:
Using above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 80 parts toothpaste substrate,
The Herb Gynostemmae Pentaphylli extract of 4 parts, the Rhizoma Polygoni Cuspidati extract of 1 part, the Radix Polygoni Multiflori extract of 1 part, the Aloe extract of 1 part and 1 part
Radix Notoginseng extract forms；Wherein said toothpaste substrate by weight by the abrasivus of 45 parts, the wetting agent of 33 parts, 2 parts
Thickening agent, the foaming agent of 2.5 parts, the spice of 0.5 part, the sweeting agent of 0.2 part, the food coloring of 0.5 part, 0.3 part
Preservative and the deionized water composition of 8 parts.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
Detection uses the Chinese medicine blood fat reducing toothpaste of embodiment 1 to brush teeth triglyceride, serum total cholesterol and low-density after a course for the treatment of
Lipoprotein content.
Test result indicate that (being shown in Table 1), after using this toothpaste one course for the treatment of, hyperlipemia is substantially alleviated.Triglyceride water
Put down and be down to 4.31 ± 0.18mmol/L by 5.07 ± 0.17mmol/L.Serum total cholesterol level is by 6.30 ± 0.12mmol/L
It is down to 5.64 ± 0.13mmol/L.Low-density lipoprotein white level is down to 3.26 ± 0.03mmol/L by 3.78 ± 0.04mmol/L.
Table 1
| Before using | After using | |
| Triglyceride (mmol/L) | 5.07±0.17 | 4.31±0.18* |
| Serum total cholesterol (mmol/L) | 6.30±0.12 | 5.64±0.13* |
| Low density lipoprotein, LDL (mmol/L) | 3.78±0.04 | 3.26±0.03* |
In 20 example study subjects, 17 examples are had to suffer from angina pectoris.Disease is twisted with reference to " Angina evaluation criteria " heart
Shape efficacy assessment standard be divided into effective, effective, invalid, increase the weight of 4 grades.To above-mentioned 17 example hyperlipemias with patient with angina pectoris
Carry out the angina pectoris classification before and after the Chinese medicine blood fat reducing toothpaste use of embodiment 1.
Test result indicate that, after using this toothpaste one course for the treatment of, angina pectoris symptom substantially alleviates.Obvious effective rate reaches 88%, effectively
Rate reaches 12%, has no invalid or increases the weight of situation (being shown in Table 2).
Table 2
| Angina pectoris | |
| Effective/example | 15 |
| Effectively/example | 2 |
| Invalid/example | 0 |
| Increase the weight of/example | 0 |
From result above, Chinese medicine Antilipemic health toothpaste described in the present embodiment, there is good blood fat reducing function, the most right
The diseases of cardiovascular and cerebrovascular systems of hyperlipemia induction has obvious functions of prevention and health care.
Embodiment 2: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 80 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 8 parts, the Rhizoma Polygoni Cuspidati extract of 3 parts, the Radix Polygoni Multiflori extract of 3 parts, the Aloe of 3 parts carry
Take the Radix Notoginseng extract composition of thing and 3 parts；Wherein said toothpaste substrate by weight by 35 parts abrasivus, 25 parts
Wetting agent, the thickening agent of 1 part, the foaming agent of 2 parts, the spice of 0.5 part, the sweeting agent of 0.2 part, the food coloring of 0.5 part,
The preservative of 0.3 part and the deionized water composition of 9.5 parts.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 2 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 14.9%；The total gallbladder of serum
Sterin reduces by 10.5%；Low density lipoprotein, LDL content reduces by 13.7%.
Embodiment 3: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 82 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 14 parts, the Rhizoma Polygoni Cuspidati extract of 1 part, the Radix Polygoni Multiflori extract of 1 part, the Aloe of 1 part
Extract and the Radix Notoginseng extract composition of 1 part；Wherein said toothpaste substrate by weight by 35 parts abrasivus, 30 parts
Wetting agent, the thickening agent of 2 parts, the foaming agent of 2 parts, the spice of 0.5 part, the sweeting agent of 0.2 part, the edible color of 0.5 part
The deionized water composition of element, the preservative of 0.3 part and 11.5 parts.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 3 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 15.1%；The total gallbladder of serum
Sterin reduces by 11.2%；Low density lipoprotein, LDL content reduces by 13.9%.
Embodiment 4: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 79 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 15 parts, the Rhizoma Polygoni Cuspidati extract of 1 part, the Radix Polygoni Multiflori extract of 1 part, the Aloe of 1 part
The Ganoderma extract composition of extract, the Radix Notoginseng extract of 1 part, the Rhizoma Curcumae Longae extract of 1 part and 1 part；Wherein said toothpaste
With substrate by weight by the abrasivus of 35 parts, the wetting agent of 30 parts, the thickening agent of 1 part, the foaming agent of 2.5 parts, 0.5
The deionized water composition of spice, the sweeting agent of 0.2 part, the food coloring of 0.5 part, the preservative of 0.3 part and 9 parts of part.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 4 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 15.3%；The total gallbladder of serum
Sterin reduces by 11.5%；Low density lipoprotein, LDL content reduces by 14.1%.
Embodiment 5: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 78 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 12 parts, the Rhizoma Polygoni Cuspidati extract of 2 parts, the Radix Polygoni Multiflori extract of 2 parts, the Aloe of 2 parts
The Herba Artemisiae Scopariae extract composition of extract, the Radix Notoginseng extract of 2 parts, the Semen Raphani extract of 1 part and 1 part；Wherein said tooth
Cream with substrate by weight by the abrasivus of 25 parts, the wetting agent of 35 parts, the thickening agent of 2 parts, the foaming agent of 2 parts, 0.5
The deionized water composition of spice, the sweeting agent of 0.2 part, the food coloring of 0.5 part, the preservative of 0.3 part and 12.5 parts of part.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 5 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 15.1%；The total gallbladder of serum
Sterin reduces by 11.8%；Low density lipoprotein, LDL content reduces by 14.3%.
Embodiment 6: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 82 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 12 parts, the Rhizoma Polygoni Cuspidati extract of 1 part, the Radix Polygoni Multiflori extract of 1 part, the Aloe of 1 part
The Radix Curcumae extract composition of extract, the Radix Notoginseng extract of 1 part, the Rhizoma Curcumae extract of 1 part and 1 part；Wherein said toothpaste
With substrate by weight by the abrasivus of 30 parts, the wetting agent of 35 parts, the thickening agent of 2 parts, the foaming agent of 2 parts, 1.5 parts
Spice, the sweeting agent of 0.2 part, the food coloring of 0.5 part, the preservative of 0.3 part and 10.5 parts deionized water composition.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 6 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 15.5%；The total gallbladder of serum
Sterin reduces by 12.1%；Low density lipoprotein, LDL content reduces by 14.6%.
Embodiment 7: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 70 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 10 parts, the Rhizoma Polygoni Cuspidati extract of 4 parts, the Radix Polygoni Multiflori extract of 4 parts, the Aloe of 4 parts
The Rhizoma Atractylodis Macrocephalae extract composition of extract, the Radix Notoginseng extract of 4 parts, the Ramulus Cinnamomi extract of 2 parts and 2 parts；Wherein said toothpaste
With substrate by weight by the abrasivus of 20 parts, the wetting agent of 40 parts, the thickening agent of 1 part, the foaming agent of 1 part, 0.5 part
Spice, the sweeting agent of 0.2 part, the food coloring of 0.5 part, the preservative of 0.3 part and 6.5 parts deionized water composition.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 7 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 15.6%；The total gallbladder of serum
Sterin reduces by 12.2%；Low density lipoprotein, LDL content reduces by 14.5%.
Embodiment 8: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 70-95 part
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 10 parts, the Rhizoma Polygoni Cuspidati extract of 2 parts, the Radix Polygoni Multiflori extract of 2 parts, the reed of 2 parts
The Radix Scrophulariae extract composition of luxuriant growth extract, the Radix Notoginseng extract of 2 parts, the Fructus Sophorae extract of 1 part and 1 part；Wherein said tooth
Cream with substrate by weight by the abrasivus of 20 parts, the wetting agent of 40 parts, the thickening agent of 1 part, the foaming agent of 1 part, 0.5
The deionized water composition of spice, the sweeting agent of 0.2 part, the food coloring of 0.5 part, the preservative of 0.3 part and 6.5 parts of part.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 8 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 15.4%；The total gallbladder of serum
Sterin reduces by 12.8%；Low density lipoprotein, LDL content reduces by 14.9%.
Embodiment 9: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 85 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 8 parts, the Rhizoma Polygoni Cuspidati extract of 1 part, the Radix Polygoni Multiflori extract of 1 part, the Aloe of 1 part carry
Take the Rhizoma Drynariae extract composition of thing, the Radix Notoginseng extract of 1 part, the Radix Paeoniae Rubra extract of 1 part and 2 parts；Wherein said toothpaste
With substrate by weight by the abrasivus of 40 parts, the wetting agent of 30 parts, the thickening agent of 1 part, the foaming agent of 2 parts, 1 part
The deionized water composition of spice, the sweeting agent of 0.2 part, the food coloring of 0.5 part, the preservative of 0.3 part and 11 parts.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 9 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 15.5%；The total gallbladder of serum
Sterin reduces by 13.2%；Low density lipoprotein, LDL content reduces by 14.9%.
Embodiment 10: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 82 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 8 parts, the Rhizoma Polygoni Cuspidati extract of 2 parts, the Radix Polygoni Multiflori extract of 2 parts, the Aloe of 2 parts carry
Take the Rhizoma Chuanxiong extract composition of thing, the Radix Notoginseng extract of 2 parts, the Radix Rhodiolae extract of 1 part and 1 part；Wherein said toothpaste
With substrate by weight by the abrasivus of 30 parts, the wetting agent of 35 parts, the thickening agent of 2 parts, the foaming agent of 2 parts, 0.5 part
Spice, the sweeting agent of 0.2 part, the food coloring of 0.5 part, the preservative of 0.3 part and 11.5 parts deionized water composition.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 10 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 15.6%；Serum is total
Cholesterol reduces by 13.8%；Low density lipoprotein, LDL content reduces by 14.6%.
Embodiment 11: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 88 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 6 parts, the Rhizoma Polygoni Cuspidati extract of 1 part, the Radix Polygoni Multiflori extract of 1 part, the Aloe of 1 part carry
Take the Radix Bupleuri extract composition of thing, the Radix Notoginseng extract of 1 part, the Rhizoma Fagopyri Dibotryis extract of 1 part and 1 part；Wherein said toothpaste
With substrate by weight by the abrasivus of 40 parts, the wetting agent of 30 parts, the thickening agent of 1 part, the foaming agent of 3 parts, 1 part
The deionized water composition of spice, the sweeting agent of 0.2 part, the food coloring of 0.5 part, the preservative of 0.3 part and 12 parts.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 11 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 15.4%；Serum is total
Cholesterol reduces by 13.9%；Low density lipoprotein, LDL content reduces by 14.8%.
Embodiment 12: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 84 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 12 parts, the Rhizoma Polygoni Cuspidati extract of 1 part, the Radix Polygoni Multiflori extract of 1 part, the Aloe of 1 part
Extract and the Radix Notoginseng extract composition of 1 part；Wherein said toothpaste substrate by weight by 38 parts abrasivus, 30 parts
Wetting agent, the thickening agent of 2 parts, the foaming agent of 2 parts, the spice of 0.5 part, the sweeting agent of 0.2 part, the edible color of 0.5 part
The deionized water composition of element, the preservative of 0.3 part and 10.5 parts.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 12 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 14.8%；Serum is total
Cholesterol reduces by 10.6%；Low density lipoprotein, LDL content reduces by 14.1%.
Embodiment 13: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 78 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 10 parts, the Rhizoma Polygoni Cuspidati extract of 2 parts, the Radix Polygoni Multiflori extract of 2 parts, the Aloe of 2 parts
The Rhizoma Fagopyri Dibotryis extract composition of extract, the Radix Notoginseng extract of 2 parts, the Herba Artemisiae Scopariae extract of 2 parts and 2 parts；Wherein said tooth
Cream with substrate by weight by the abrasivus of 36 parts, the wetting agent of 28 parts, the thickening agent of 2 parts, the foaming agent of 3 parts, 0.5
The deionized water composition of spice, the sweeting agent of 0.2 part, the food coloring of 0.5 part, the preservative of 0.3 part and 8.5 parts of part.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 13 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 15.6%；Serum is total
Cholesterol reduces by 11.8%；Low density lipoprotein, LDL content reduces by 14.9%.
Embodiment 14: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 85 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 10 parts, the Rhizoma Polygoni Cuspidati extract of 1 part, the Radix Polygoni Multiflori extract of 1 part, the Aloe of 1 part
The Rhizoma Chuanxiong extract composition of extract, the Radix Notoginseng extract of 1 part and 1 part；Wherein said toothpaste substrate is by weight by 38
The abrasivus of part, the wetting agent of 28 parts, the thickening agent of 2 parts, the foaming agent of 3 parts, the spice of 0.5 part, the sweet taste of 0.2 part
The deionized water composition of agent, the food coloring of 0.5 part, the preservative of 0.3 part and 12.5 parts.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 14 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 14.8%；Serum is total
Cholesterol reduces by 11.2%；Low density lipoprotein, LDL content reduces by 14.8%.
Embodiment 15: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 88 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 8 parts, the Rhizoma Polygoni Cuspidati extract of 1 part, the Radix Polygoni Multiflori extract of 1 part, the Aloe of 1 part carry
Take the Radix Notoginseng extract composition of thing and 1 part；Wherein said toothpaste substrate by weight by 42 parts abrasivus, 32 parts
Wetting agent, the thickening agent of 1 part, the foaming agent of 3 parts, the spice of 0.5 part, the sweeting agent of 0.2 part, the food coloring of 0.5 part,
The preservative of 0.3 part and the deionized water composition of 8.5 parts.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 15 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 14.2%；Serum is total
Cholesterol reduces by 10.6%；Low density lipoprotein, LDL content reduces by 13.8%.
Embodiment 16: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 89 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 6 parts, the Rhizoma Polygoni Cuspidati extract of 1 part, the Radix Polygoni Multiflori extract of 1 part, the Aloe of 1 part carry
Take the Semen Raphani extract composition of thing, the Radix Notoginseng extract of 1 part and 1 part；Wherein said toothpaste substrate is by weight by 41
The abrasivus of part, the wetting agent of 31 parts, the thickening agent of 2 parts, the foaming agent of 3 parts, the spice of 0.5 part, the sweet taste of 0.2 part
The deionized water composition of agent, the food coloring of 0.5 part, the preservative of 0.3 part and 10.5 parts.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 16 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 14.9%；Serum is total
Cholesterol reduces by 11.3%；Low density lipoprotein, LDL content reduces by 14.2%.
Embodiment 17: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 89 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 5 parts, the Rhizoma Polygoni Cuspidati extract of 1 part, the Radix Polygoni Multiflori extract of 1 part, the Aloe of 1 part carry
Take the Radix Notoginseng extract composition of thing and 1 part；Wherein said toothpaste substrate by weight by 42 parts abrasivus, 30 parts
Wetting agent, the thickening agent of 2 parts, the foaming agent of 3 parts, the spice of 0.5 part, the sweeting agent of 0.2 part, the food coloring of 0.5 part,
The preservative of 0.3 part and the deionized water composition of 12.5 parts.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 17 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 14.1%；Serum is total
Cholesterol reduces by 10.6%；Low density lipoprotein, LDL content reduces by 13.9%.
Embodiment 18: use above-mentioned preparation method, Ingredient Amount is as follows: Chinese medicine blood fat reducing toothpaste, by weight by 83 parts
Toothpaste substrate, the Herb Gynostemmae Pentaphylli extract of 6 parts, the Rhizoma Polygoni Cuspidati extract of 2 parts, the Radix Polygoni Multiflori extract of 2 parts, the Aloe of 2 parts carry
Take thing, the Radix Notoginseng extract of 2 parts, the Radix Scrophulariae extract of 1 part, the Ganoderma extract of 1 part and the Radix Rhodiolae extract of 1 part
Composition；Wherein said toothpaste substrate by weight by the abrasivus of 40 parts, the wetting agent of 32 parts, the thickening agent of 2 parts, 3
The foaming agent of part, the spice of 0.5 part, the sweeting agent of 0.2 part, the food coloring of 0.5 part, the preservative of 0.3 part and 12.5
The deionized water composition of part.
Toothpaste using method is: patient every day early, respectively brush teeth once evening, brushing time 2-5min, consumption is each 2g.
The course for the treatment of: 30 days be a course for the treatment of.
The Chinese medicine blood fat reducing toothpaste using embodiment 18 is brushed teeth a course for the treatment of, after testing: triglyceride reduces by 15.2%；Serum is total
Cholesterol reduces by 12.3%；Low density lipoprotein, LDL content reduces by 14.6%.
Claims (10)
1. Chinese medicine blood fat reducing toothpaste, it is characterised in that it is by weight by the toothpaste substrate of 70-95 part, the Herb Gynostemmae Pentaphylli of 1-10 part
The Radix Notoginseng of extract, the Rhizoma Polygoni Cuspidati extract of 1-5 part, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe extract of 1-5 part and 1-5 part carries
Take thing composition；Wherein said toothpaste substrate is by weight by the abrasivus of 12-60 part, the wetting agent of 5-60 part, 0.5-4 part
Thickening agent, the foaming agent of 1-5.5 part, the spice of 0-2 part, the sweeting agent of 0-1 part, the food coloring of 0-1 part, 0-0.5 part
Preservative and 6-33.5 part deionized water composition.
Chinese medicine blood fat reducing toothpaste the most according to claim 1, it is characterised in that described Chinese medicine blood fat reducing toothpaste, by weight by
The toothpaste substrate of 80 parts, the Herb Gynostemmae Pentaphylli extract of 8 parts, the Rhizoma Polygoni Cuspidati extract of 3 parts, the Radix Polygoni Multiflori extract of 3 parts, 3 parts
Aloe extract and the Radix Notoginseng extract composition of 3 parts.
Chinese medicine blood fat reducing toothpaste the most according to claim 1, it is characterised in that described toothpaste substrate is by weight by 50
The deionized water composition of abrasivus, the wetting agent of 10 parts, the thickening agent of 3 parts, the foaming agent of 5 parts and 32 parts of part.
4. the method preparing Chinese medicine blood fat reducing toothpaste as claimed in claim 1, it is characterised in that it sequentially includes the following steps:
One, the abrasivus of 12-60 part, the wetting agent of 5-60 part, the thickening agent of 0.5-4 part, 1-5.5 part are weighed by weight
Foaming agent, the spice of 0-2 part, the sweeting agent of 0-1 part, the food coloring of 0-1 part, the preservative of 0-0.5 part, 6-33.5 part
Deionized water, then mix, it is thus achieved that toothpaste substrate；
Two, Herb Gynostemmae Pentaphylli, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe and Radix Notoginseng are pulverized after over cleaning respectively, carry out active component the most respectively
Extraction, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, Radix Polygoni Multiflori extract, Aloe extract and Radix Notoginseng extract；
Three, the Rhizoma Polygoni Cuspidati extraction of the toothpaste substrate of 70-95 part, the Herb Gynostemmae Pentaphylli extract of 1-10 part, 1-5 part is weighed by weight
Thing, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe extract of 1-5 part and the Radix Notoginseng extract of 1-5 part, mix homogeneously is placed on very
In empty Manufacturing medicine extract machine, keep vacuum at-0.09MPa～-0.096MPa, carry out fill after homogenizing process stirs, i.e. complete
The preparation of Chinese medicine blood fat reducing toothpaste；
Wherein said abrasivus is calcium phosphate dibasic anhydrous, dicalcium phosphate dehydrate, anhydride silica, anhydrous calcium pyrophosphate, carbon
Any combination of one or more in acid calcium, clinochlore powder, calcite in powder, aluminium hydroxide；
Wetting agent is any combination of one or more in glycerol, propylene glycol, glycerol, Polyethylene Glycol, sorbitol；
Thickening agent is sodium carboxymethyl cellulose, carbomer, carboxyethyl cellulose, hydroxypropyl melon glue, carrageenan, thickening
Any combination of one or more in type silicon dioxide, colloidality aluminium-magnesium silicate, sodium alginate, yellow natural gum powder；
Foaming agent is sodium lauryl sulphate, acyl glutamic acid sodium, sodium lauroyl sarcosine, methyl cocoa aliphatic radical sodium taurocholate
In any combination of one or more；
Spice is purple lemon sesame oil, orange oil, mandarin oil, Soviet Union's oil, Oleum Menthae Rotundifoliae, wintergreen oil, Oleum Caryophylli, Oleum Cinnamomi, fennel
Appointing of one or more in Oleum sesami, Oleum menthae, Mentholum, Borneolum Syntheticum, lauryl aldehyde, citral, vanillin, pentyl acetate
Meaning is than combination；
Sweeting agent is sucrose, saccharin, cyclamate, xylitol, stevioside, disodium glycyrrhizinate, tripotassium glycyrrhetate and glycyrrhizic acid
Any combination of one or more in trisodium；
Food coloring is purple, pink colour, blue or green；
Preservative be one or more in p-Hydroxybenzoate, sodium benzoate, potassium sorbate, sorbitol arbitrarily than group
Close.
The preparation method of Chinese medicine blood fat reducing toothpaste the most according to claim 4, it is characterised in that active component in step 2
Extract as follows: Herb Gynostemmae Pentaphylli, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe and the Radix Notoginseng after pulverizing, add 8 respectively～the deionized water of 16 times of volumes
Decoct 2 times, each 1h, the extracting solution every time decocting gained is filtered, and with activated carbon decolorizing, all concentrate as proportion 1.10-1.30
Extractum, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, Radix Polygoni Multiflori extract, Aloe extract and Radix Notoginseng extract.
The preparation method of Chinese medicine blood fat reducing toothpaste the most according to claim 4, it is characterised in that active component in step 2
Extracting can also be as follows: Herb Gynostemmae Pentaphylli, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe and the Radix Notoginseng after pulverizing, adds 8 respectively～the matter of 16 times of volumes
Amount concentration is the alcohol reflux 3 times of 70%, each 2h, and the extracting solution that will every time decoct gained filters, and uses activated carbon
Decolouring, all concentrates the extractum for proportion 1.10-1.30, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, Radix Polygoni Multiflori extract, reed
Luxuriant growth extract and Radix Notoginseng extract.
7. Chinese medicine blood fat reducing toothpaste, it is characterised in that it is by weight by the toothpaste substrate of 70-95 part, the Herb Gynostemmae Pentaphylli of 1-10 part
The Radix Notoginseng of extract, the Rhizoma Polygoni Cuspidati extract of 1-5 part, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe extract of 1-5 part and 1-5 part carries
Take thing composition, also include the Rhizoma Alismatis extract of 1-2 part, the Radix Et Rhizoma Rhei extract of 1-2 part, the Rhizoma Curcumae Longae extract of 1-2 part, 1-2 part
Ganoderma extract, the Semen Raphani extract of 1-2 part, the Herba Artemisiae Scopariae extract of 1-2 part, the Rhizoma Curcumae extract of 1-2 part, 1-2 part
Radix Curcumae extract, the Ramulus Cinnamomi extract of 1-2 part, the Rhizoma Atractylodis Macrocephalae extract of 1-2 part, the Fructus Sophorae extract of 1-2 part, 1-2 part
Radix Scrophulariae extract, the Radix Paeoniae Rubra extract of 1-2 part, the Rhizoma Drynariae extract of 1-2 part, the Rhizoma Chuanxiong extract of 1-2 part, 1-2 part
Radix Rhodiolae extract, the Rhizoma Fagopyri Dibotryis extract of 1-2 part, 1-2 part Radix Bupleuri extract in 1-3 kind；Wherein said toothpaste is used
Substrate by weight by the abrasivus of 12-60 part, the wetting agent of 5-60 part, the thickening agent of 0.5-4 part, the foaming agent of 1-5.5 part,
The spice of 0-2 part, the sweeting agent of 0-1 part, the food coloring of 0-1 part, the preservative of 0-0.5 part and the deionization of 6-33.5 part
Water forms.
Chinese medicine blood fat reducing toothpaste the most according to claim 7, it is characterised in that described Chinese medicine blood fat reducing toothpaste, by weight by
The toothpaste substrate of 85 parts, the Herb Gynostemmae Pentaphylli extract of 3 parts, the Rhizoma Polygoni Cuspidati extract of 3 parts, the Radix Polygoni Multiflori extract of 3 parts, 1 part
Aloe extract and the Radix Notoginseng extract composition of 1 part, also include the Ganoderma extract of 2 parts, the Semen Raphani extract of 2 parts.
Chinese medicine blood fat reducing toothpaste the most according to claim 7, it is characterised in that described Chinese medicine blood fat reducing toothpaste, by weight by
The toothpaste substrate of 90 parts, the Herb Gynostemmae Pentaphylli extract of 2 parts, the Rhizoma Polygoni Cuspidati extract of 2 parts, the Radix Polygoni Multiflori extract of 1 part, 1 part
Aloe extract and the Radix Notoginseng extract composition of 2 parts, also include the Radix Scrophulariae extract of 2 parts.
10. the method preparing Chinese medicine blood fat reducing toothpaste as claimed in claim 7, it is characterised in that it sequentially includes the following steps:
One, the abrasivus of 12-60 part, the wetting agent of 5-60 part, the thickening agent of 0.5-4 part, 1-5.5 part are weighed by weight
Foaming agent, the spice of 0-2 part, the sweeting agent of 0-1 part, the food coloring of 0-1 part, the preservative of 0-0.5 part, 6-33.5 part
Deionized water, then mix, it is thus achieved that toothpaste substrate；
Two, Herb Gynostemmae Pentaphylli, Rhizoma Polygoni Cuspidati, the Radix Polygoni Multiflori, Aloe, Radix Notoginseng, Rhizoma Alismatis, Radix Et Rhizoma Rhei, Rhizoma Curcumae Longae, Ganoderma, Semen Raphani, Herba Artemisiae Scopariae,
Rhizoma Curcumae, Radix Curcumae, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, the Fructus Sophorae, Radix Scrophulariae, Radix Paeoniae Rubra, Rhizoma Drynariae, Rhizoma Chuanxiong, Radix Rhodiolae, Rhizoma Fagopyri Dibotryis and Radix Bupleuri warp
Pulverize respectively after over cleaning, carry out the extraction of active component the most respectively, it is thus achieved that Herb Gynostemmae Pentaphylli extract, Rhizoma Polygoni Cuspidati extract, head
Crow extract, Aloe extract, Radix Notoginseng extract, Rhizoma Alismatis extract, Radix Et Rhizoma Rhei extract, Rhizoma Curcumae Longae extract, Ganoderma are extracted
Thing, Semen Raphani extract, Herba Artemisiae Scopariae extract, Rhizoma Curcumae extract, Radix Curcumae extract, Ramulus Cinnamomi extract, Rhizoma Atractylodis Macrocephalae extract,
Fructus Sophorae extract, Radix Scrophulariae extract, Radix Paeoniae Rubra extract, Rhizoma Drynariae extract, Rhizoma Chuanxiong extract, Radix Rhodiolae extract, gold
Semen Fagopyri Esculenti extract and Radix Bupleuri extract；
Three, weigh by weight the Rhizoma Alismatis extract of 1-2 part, the Radix Et Rhizoma Rhei extract of 1-2 part, the Rhizoma Curcumae Longae extract of 1-2 part,
The Ganoderma extract of 1-2 part, the Semen Raphani extract of 1-2 part, the Herba Artemisiae Scopariae extract of 1-2 part, the Rhizoma Curcumae extract of 1-2 part,
The Radix Curcumae extract of 1-2 part, the Ramulus Cinnamomi extract of 1-2 part, the Rhizoma Atractylodis Macrocephalae extract of 1-2 part, the Fructus Sophorae extract of 1-2 part, 1-2
The Radix Scrophulariae extract of part, the Radix Paeoniae Rubra extract of 1-2 part, the Rhizoma Drynariae extract of 1-2 part, the Rhizoma Chuanxiong extract of 1-2 part, 1-2
Part Radix Rhodiolae extract, the Rhizoma Fagopyri Dibotryis extract of 1-2 part, 1-2 part Radix Bupleuri extract in 1-3 kind, be subsequently adding 1-10
The Herb Gynostemmae Pentaphylli extract of part, the Rhizoma Polygoni Cuspidati extract of 1-5 part, the Radix Polygoni Multiflori extract of 1-5 part, the Aloe extract of 1-5 part, 1-5
The Radix Notoginseng extract of part and the toothpaste substrate of 70-95 part, mix homogeneously is placed in vacuum Manufacturing medicine extract machine, keeps vacuum to exist
-0.09MPa～-0.096MPa, carries out fill after homogenizing process stirs, i.e. completes the preparation of Chinese medicine blood fat reducing toothpaste；
Wherein said abrasivus is calcium phosphate dibasic anhydrous, dicalcium phosphate dehydrate, anhydride silica, anhydrous calcium pyrophosphate, carbon
Any combination of one or more in acid calcium, clinochlore powder, calcite in powder, aluminium hydroxide；
Wetting agent is any combination of one or more in glycerol, propylene glycol, glycerol, Polyethylene Glycol, sorbitol；
Thickening agent is sodium carboxymethyl cellulose, carbomer, carboxyethyl cellulose, hydroxypropyl melon glue, carrageenan, thickening
Any combination of one or more in type silicon dioxide, colloidality aluminium-magnesium silicate, sodium alginate, yellow natural gum powder；
Foaming agent is sodium lauryl sulphate, acyl glutamic acid sodium, sodium lauroyl sarcosine, methyl cocoa aliphatic radical sodium taurocholate
In any combination of one or more；
Spice is purple lemon sesame oil, orange oil, mandarin oil, Soviet Union's oil, Oleum Menthae Rotundifoliae, wintergreen oil, Oleum Caryophylli, Oleum Cinnamomi, fennel
Appointing of one or more in Oleum sesami, Oleum menthae, Mentholum, Borneolum Syntheticum, lauryl aldehyde, citral, vanillin, pentyl acetate
Meaning is than combination；
Sweeting agent is sucrose, saccharin, cyclamate, xylitol, stevioside, disodium glycyrrhizinate, tripotassium glycyrrhetate and glycyrrhizic acid
Any combination of one or more in trisodium；
Food coloring is purple, pink colour, blue or green；
Preservative be one or more in p-Hydroxybenzoate, sodium benzoate, potassium sorbate, sorbitol arbitrarily than group
Close.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107308098A (en) * | 2017-07-20 | 2017-11-03 | 何家平 | A kind of Li Lu children's toothpastes technique |
| CN107334683A (en) * | 2017-07-26 | 2017-11-10 | 何家平 | A kind of children's toothpaste containing Chinese herbal medicine |
| CN111084741A (en) * | 2019-12-30 | 2020-05-01 | 柳州两面针股份有限公司 | Application of red peony root extract in preparation of oral care products |
| CN112137938A (en) * | 2020-11-03 | 2020-12-29 | 广州市盛龙口腔清洁用品有限公司 | Gynostemma pentaphylla traditional Chinese medicine toothpaste |
| CN117205140A (en) * | 2023-09-03 | 2023-12-12 | 真臻(宿迁)生物科技有限公司 | A lipid-lowering toothpaste containing a biological enzyme-based composition and its preparation method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6485711B1 (en) * | 2002-03-21 | 2002-11-26 | Michael J. Olmstead | Organic toothpaste containing saponin |
| CN101112376A (en) * | 2007-08-27 | 2008-01-30 | 喜巍 | Toothpaste for nursing cardiac and cerebral blood vessel |
-
2016
- 2016-04-07 CN CN201610213253.6A patent/CN105832594A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6485711B1 (en) * | 2002-03-21 | 2002-11-26 | Michael J. Olmstead | Organic toothpaste containing saponin |
| CN101112376A (en) * | 2007-08-27 | 2008-01-30 | 喜巍 | Toothpaste for nursing cardiac and cerebral blood vessel |
Non-Patent Citations (2)
| Title |
|---|
| 庄瑞丰: "中药降血脂作用研究进展", 《河北医药》 * |
| 陈长勋: "《中药药理学》", 31 January 2015, 上海科学技术出版社 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107308098A (en) * | 2017-07-20 | 2017-11-03 | 何家平 | A kind of Li Lu children's toothpastes technique |
| CN107334683A (en) * | 2017-07-26 | 2017-11-10 | 何家平 | A kind of children's toothpaste containing Chinese herbal medicine |
| CN111084741A (en) * | 2019-12-30 | 2020-05-01 | 柳州两面针股份有限公司 | Application of red peony root extract in preparation of oral care products |
| CN112137938A (en) * | 2020-11-03 | 2020-12-29 | 广州市盛龙口腔清洁用品有限公司 | Gynostemma pentaphylla traditional Chinese medicine toothpaste |
| CN117205140A (en) * | 2023-09-03 | 2023-12-12 | 真臻(宿迁)生物科技有限公司 | A lipid-lowering toothpaste containing a biological enzyme-based composition and its preparation method |
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Application publication date: 20160810 |