CN105794814A - Insecticidal composition and agricultural insect control method - Google Patents

Abstract

The invention relates to an insecticidal composition. The insecticidal composition comprises pyrifluquinazon and flufenoxuron. The invention especially relates to an agricultural insect control method. A weight ratio of pyrifluquinazon to flufenoxuron is 1: 100 to 100: 1. The invention discloses a method for preventing or controlling agricultural insects. The method utilizes the insecticidal composition for a target useful plant, a target agricultural insect or its environment, and a target useful plant propagating material. The invention discloses a method for preventing agricultural insect attack. The method comprises utilizing the insecticidal composition for plants, a plant propagating material and an environment before and/or after insect attack.

Description

A kind of insecticidal composition and method for controlling agricultural pests

technical field

The invention relates to an insecticidal composition, which comprises flubizuron and flubenzuron; in particular, it relates to a method for controlling agricultural pests.

Background technique

Chemical control is an important means of preventing and controlling pests in agriculture. However, at present, due to the types of pests, their living characteristics, their living environment, etc., they may not be able to effectively control them due to poor effects, strong resistance, and the like. Especially for pests of Lepidoptera, Coleoptera, Diptera, Homoptera, Hemiptera, Hymenoptera, Thysanoptera, Arachnida and Nematodes, the use of conventional pesticides for prevention and control is positive. become increasingly difficult. Therefore, in order to effectively prevent and control impossible or difficult pests, it is necessary to seek a new means and method.

Rice borer, rice leaf roller, tea geometrid, beet armyworm, litura, diamondback moth, rice planthopper, aphid, spider mite, thrips, whitefly, greenhouse whitefly for rice, wheat, corn, cotton , vegetables, fruit trees, tea and other common pests on plants. If no corresponding measures are taken against pests, it will definitely affect the growth of agricultural plants.

Pyrifluquinazon, chemical name: (1-acetyl-1,2,3,4-tetrahydro-3-[(3-pyridylmethyl)amino]-6-[1,2, 2,2,-Tetrafluoro-1-(trifluoromethyl)ethyl]quinazolin-2-one; Fluramidine is known and described, for example, in EP1097932; its molecular structure is (formula I) :

Formula (I)

Fluramid, developed by Nippon Pesticide Company, belongs to a new class of quinazoline (diazoline) insecticides. Fluramiquin is generally used in water-dispersible granules, and its mechanism of action is to stop pests from feeding and starve to death, thereby preventing more damage to plant tissues and controlling the spread of some important diseases. At present, it is mainly used to control whiteflies, aphids and scale insects on vegetables, fruit trees and tea.

Flufenoxuron (Flufenoxuron), 1-[2-fluoro-4-(2-chloro-4-trifluoromethylphenoxy)phenyl]-3-(2,6-difluorobenzoyl)urea, Molecular formula: C ₂₁ H ₁₁ ClF ₆ N ₂ O ₃ , structural formula:

Formula (II)

Flubenzuron belongs to benzoylurea insecticides and is an inhibitor of chitin synthesis. Its insecticidal activity, insecticidal spectrum and action speed are all unique, and it has good leaf retention. It is especially active against mites and pests in the immature stage, and is widely used in citrus, cotton, grapes, soybeans, fruit trees, corn and coffee to prevent and control plant-eating mites (etrophic gall mites, short beard mites, panonychia mites) , rust mite, red spider mite, etc.) and many other pests, and has a good long-lasting effect, safe for predatory mites and insects. Flubenzuron is mainly used to control pests and mites on apples, citrus and other fruit trees, vegetables, cotton and other plants. Pests such as moths, borers, noctuids, and locusts all have good control effects. However, the killing effect of fiflubenzuron is relatively slow, so the application time should be 2-3 days earlier than that of general insecticides and acaricides. For the control of borer pests, it is advisable to apply pesticides from the peak of egg hatching to before the larvae enter the crops. When mites are infested, it is advisable to apply pesticides in the period when young mites and borrowed mites are in full bloom.

The activity of the individual compounds of Fflubendraquine or Fluflubenzuron is good; however, at low application rates or against specific pests, they sometimes do not meet the high requirements that insecticides must meet.

A typical objective arising in the field of pest control is the need to reduce the dosage rate of the control active ingredient and reduce or avoid adverse environmental or toxicological effects, while still allowing effective insecticides.

There is also a need in the field of pest control for pest control agents that combine fast-acting and long-lasting action, ie, insecticides that combine knockdown activity with long-lasting control.

Whereas repeated and single applications of individual pesticide compounds lead in many cases to a rapid selection of pests which have acquired natural or adapted resistance to the active ingredient in question. Accordingly, there is also a need in the field of pest control for insecticides that help control or overcome resistance.

Contents of the invention

The purpose of the present invention is to solve the above-mentioned technical problems, and to provide an insecticidal composition. By combining fiflubenzaquin and flubenzuron, the obtained composition has a gain effect on the control effect, and expands It improves the insecticidal spectrum, improves the rapid and long-term effects of pest control, and delays the emergence of drug resistance.

It has now been found that the combination of fiflubenzaquin and flubendron has a synergistic effect and is particularly suitable for controlling agricultural pests.

The technical scheme that the present invention solves its technical problem adopts is:

An insecticidal composition, comprising fluoripraquine and fluoridenuron, the ratio by weight of fluoridenil and fluoridenuron is 1:100-100:1.

As a further improvement of the present invention, the ratio by weight of the said fluoriprazine and flufenuron is 1:50-50:1.

As a further improvement of the present invention, the ratio by weight of the fluorinated pyriquine and flufenuron is 1:25-25:1.

As a further improvement of the present invention, the ratio by weight of the fluoride and fluoride is 1:10-10:1.

An insecticidal composition, comprising fluoriprazine and fiflubenzuron, the weight of said flubendraquine and fiflubenzuron together accounts for 1%-90% of the composition by weight.

An insecticidal composition, comprising fluoriprazine and fiflubenzuron, and the fluoriprazine and fiflubenzuron together account for 10%-80% of the composition by weight.

An insecticidal composition, comprising fluoriprazine and fiflubenzuron, and the total amount of the fluoriprazine and fiflubenzuron accounts for 20%-60% of the composition by weight.

According to the pesticidal composition of the present invention, a surfactant and/or an extender are also included.

According to the pesticidal composition of the present invention, the pesticidal composition can be formulated into any dosage form acceptable in agriculture.

According to the insecticidal composition of the present invention, the dosage form of the insecticidal composition is emulsifiable concentrate, suspension concentrate, seed treatment agent, water dispersible granule, wettable powder, suspoemulsion, aerosol, water emulsion, microcapsule suspension, Microcapsule suspension-suspension concentrate, ultra-low volume liquid, microemulsion.

On the other hand, the present invention also provides a use of the pesticidal composition of the present invention for preventing or controlling agricultural pests.

The present invention provides a use of the pesticidal composition of the present invention for preventing or controlling agricultural pests that attack plants or plant propagation materials.

The plant propagation materials are seedlings, rhizomes, nursery seedlings, cuttings or seeds.

The agricultural pests are scale insects, rice stem borers, rice leaf rollers, tea geometrids, beet armyworms, Spodoptera litura, diamondback moths, rice planthoppers, aphids, thrips, whitefly, greenhouse whitefly, tea small Green leafhopper, spider mite, cabbage caterpillar, cotton bollworm.

On the other hand, the present invention also provides a method for preventing or controlling agricultural pests, using the pesticidal composition of the present invention on the target agricultural pests and/or their environment.

A method for protecting plants from agricultural pests, comprising contacting a pesticidal composition containing sulfflubenzie and flubendron with target useful plants, target agricultural pests and/or their environment, and propagation material of target useful plants.

A method of protecting plants from attack by agricultural pests comprising the separate, sequential or simultaneous application of flubendraquine and flubendron.

A method of preventing or controlling agricultural pests, wherein each of flubendraquine and flubendron is in the form of a formulated composition.

A method of protecting plants from agricultural pests, comprising applying the pesticidal composition of the present invention before and/or after infestation of plants, plant propagation materials such as seeds, or environmental pests.

A method for protecting plant seeds, which comprises contacting the seeds with an effective amount of the pesticidal composition of the present invention before sowing and/or after accelerating germination.

Use of the pesticidal composition of the present invention for treating seeds.

The present invention has the following five points through the benefits of compounding the two:

A. The synergistic effect on pests is obvious. While reducing the dosage rate of active ingredients and reducing or avoiding adverse environmental or toxicological effects, it still exhibits excellent insecticidal activity.

B. Combining fast-acting and long-lasting effects;

C. Prevent or overcome drug resistance, delaying the emergence of resistance:

D. Expansion of the control spectrum: Fluramid and pyriquine have good control effects on whiteflies, aphids and scale insects. After being mixed with flufenuron, it can effectively control scale insects, rice stem borers, rice leaf rollers, and tea leaf rollers. Inchworm, beet armyworm, Spodoptera litura, diamondback moth, rice planthopper, aphids, thrips, whitefly, greenhouse whitefly, tea green leafhopper, red spider, cabbage caterpillar, cotton bollworm.

detailed description

The present invention finds that the combination of fiflubenzaquin and fiflubenzuron not only brings about an increase in the additivity of the insecticidal spectrum, but also achieves a surprising synergistic effect.

The term "synergy" used herein means that the insecticidal effect of the combination of active ingredients of the present invention is greater than the sum of the effects of each active ingredient, or that the effect is superadditive.

The invention provides an insecticidal composition comprising fluoripraquine and fluorfenuron.

The invention provides an insecticidal composition, wherein the weight ratio of flubendraquine and flubendron is 1:100-100:1, preferably 1:50-50:1, and more preferably 1:25-25:1 , more preferably 1:10-10:1.

The total amount of active ingredient in the compositions of the present invention may be selected according to particular factors to achieve the desired effect. Such factors are, for example, dosage form, subject to be administered, method of administration, and the like. Fflubendraquine and fiflubenzuron together represent 1% to 90%, preferably 10% to 80%, more preferably 20% to 60% by weight of the composition.

The compositions of the present invention may optionally contain agronomically acceptable surfactants or extenders.

According to the invention, the term "filler" refers to a natural or synthetic organic or inorganic compound which can be combined or associated with an active compound to make it easier to apply to a subject, such as a plant, crop or grass. Therefore, the carrier is preferably inert and at least should be agronomically acceptable. The filler can be solid or liquid.

Liquid fillers suitable for the preparation of the present invention include water, alcohols (e.g. methanol, ethanol), ketones (e.g. acetone, methyl ethyl ketone), aromatic hydrocarbons (e.g. benzene, toluene, xylene, ethylbenzene, toluene naphthalene), aliphatic hydrocarbons (such as n-hexane, cyclohexane, kerosene), esters (such as ethyl acetate, butyl acetate), nitriles (such as acetonitrile, isobutyronitrile), ethers (such as di Oxane, diisopropyl ether), acid amides (such as N,N-dimethylformamide, dimethylacetamide) and halogenated hydrocarbons (such as dichloroethane, trichloroethylene, carbon tetrachloride) Wait.

The solid filler suitable for the present invention can be diatomaceous earth, magnesium aluminum silicate, attapulgite, kaolin, clay, gypsum, bentonite, white carbon black, light calcium carbonate, limestone, wood chips, corn starch, soluble starch and the like.

In order to emulsify, disperse, solubilize, and/or moisten the active ingredient compound, surfactants such as fatty alcohol polyoxyethylene ether, polyoxyethylene alkyl aryl ether, polyoxyethylene higher fatty acid ester, polyoxyethylene Phosphate esters of oxyethylene alcohols or phenols, fatty acid esters of polyols, naphthalenesulfonic acid polymers, lignosulfonates, polymer comb-shaped branched copolymers, butylnaphthalenesulfonates, alkylarylsulfonates salt, sodium alkyl sulfosuccinate, oil, fatty alcohol and ethylene oxide condensate, polyacrylate salt of alkyl taurate, protein hydrolyzate. Suitable oligosaccharides or polymers are eg based on vinylic monomers, acrylic acid, polyoxyethylene and/or polyoxypropylene alone or in combination with eg (poly)alcohols or (poly)amines.

In order to disperse, stabilize and adhere the active ingredient compound, for example, xanthan gum, magnesium aluminum silicate, gelatin, starch, cellulose methyl ether, polyvinyl alcohol, polyvinyl acetate and natural phospholipids (such as cephalin and egg Phospholipids) and auxiliary agents such as synthetic phospholipids, bentonite, and sodium lignosulfonate.

Antifreeze can choose ethylene glycol, propylene glycol, glycerol, sorbitol.

As the deflocculating agent for suspension products, auxiliary agents such as naphthalenesulfonic acid polymers and polymeric phosphates can be used. Silicone defoamers can be used as defoamers.

To improve the fluidity of solid products, auxiliary agents such as paraffins, stearates, alkyl phosphates, etc. can be used.

Colorants that can be used, such as inorganic pigments such as iron oxide, titanium oxide and Prussian blue; and organic pigments/dyes: alizarin dyes, azo dyes and metal phthalocyanine dyes; and trace elements such as iron salts, manganese salts, Salts of boron, copper, cobalt, molybdenum and zinc.

Optionally, other additional components can also be included, such as protective colloids, adhesives, thickeners, thixotropes, penetrants, stabilizers, masking agents.

The dosage form of the insecticidal composition of the present invention is: aerosol, suspension, microcapsule, fine granule, flowable concentrate, ready-to-use solution, powder, water emulsion, oil emulsion, microparticle, oil dispersion powder , oil-miscible liquid concentrate, oil-miscible liquid, foam, paste, suspension concentrate, suspoemulsion, soluble concentrate, soluble powder, granule, water-soluble granule and/or tablet, water-soluble powder, Wettable powders, natural or synthetic materials impregnated with active compounds, microcapsules in polymeric materials and water-dispersible granules.

In a preferred embodiment, the pesticide insecticidal composition is a suspension, water dispersible granule, wettable powder, suspoemulsion, emulsifiable concentrate, seed coating, wettable powder, extruded granule, coated granule, Aerosol, water emulsion, microcapsule suspension.

The formulations according to the invention can be prepared by mixing the active compounds with customary additives in a known manner. The conventional additives such as conventional extenders as well as solvents or diluents, emulsifiers, dispersants, and/or adhesives or fixatives, wetting agents, water repellents, and if necessary, driers and colorants , stabilizers, pigments, defoamers, preservatives, thickeners, water and other processing aids.

These compositions include not only ready-to-apply to the subject to be treated by means of suitable equipment, such as spraying or dusting, but also concentrated commercial compositions which require dilution before application to the subject.

The pesticidal composition of the present invention may be used as it is, or may be used in its formulation form or a use form prepared therefrom according to its respective physical and/or chemical properties.

The pesticidal composition of the present invention can also be applied in combination with other active ingredients such as fungicides, bactericides, attractants, insecticides, acaricides, nematocides, growth regulators, herbicides, agents, safeners, fertilizers or semiochemicals, etc.

The insecticidal composition of the present invention has good phytocompatibility and favorable homeothermic animal toxicity, and is suitable for preventing and controlling harmful organisms encountered in agriculture, forestry, protection of stored products and materials, and hygiene fields, especially insects, spiders, etc. morpha and nematodes. They are preferably used as crop protection compositions for foliar treatment and soil treatment. The pesticidal compositions of the invention are active against normally sensitive and resistant species and against all or individual stages of development.

The term "pest" is used herein to mean any organism that can cause damage to the normal state of a plant. include:

Lepidoptera pests include, for example, chilosuppressalis (walker), tryporyzaincertulas (walker), rice leaf roller (cnaphalocrocismedinalis Guenee), cabbage borer (hellullaundalis), peach borer (conogethespunctiferlis), citrus Orange swallowtail (papilioxuthus), white white butterfly (pierisrapaecrucivora), straight-grained rice butterfly (parnaraguttata), canopy caterpillar (malacosoma Neutriestacea), gypsy moth (lymantriadispar), American white moth (hyphantriacuunea), eastern poisonous moth (euproctis subflava), black-spotted moth Moth (Scopelodes contracus), Cotton bollworm (Helicoverpa armigera), Pink bollworm (Pinkbollworm), Trichoplusiani, Cabbage armyworm (Mamestrabrassicae), Beet armyworm (Spodoptera exigua), Spodoptera litura, Tea small Leaf tortrix (adoxophyesoranafasciata), leaf tortrix (adoxophyeshonmai), apricot yellow tortrix (archips fuscocureanus), tea long tortrix (homona magnanima), diamondback moth (plutellaxylotella), cotton red bollworm (pectinophoragossypiella).

Coleopteran pests include, for example: rice weevil (sitophilus ryzaelinne), citrus leafminer (Podagricomelanigricollis Che), corn weevil (S. ), Fleabeetle, Alticachalybea, Phyllottretastriolata, Epitrixcucumeris, Ehirtipennis, E.fuscula, Aulacophoraindica ( Gemlin), mustard leaf beetle (Phaedoncochleariae), etc.

Pests of the order Diptera include, for example: agromyzaoryzae, barley waterfly (hydrellia griseola), gerbera leafminer (liriomyzatrifolii), pea leafminer (chromatomyia horticola), tomato leafminer (liriomyzabryoniae), gray field fly (deliaplatura), onion field fly (deliaantiqua), Mediterranean fruit fly (ceratitis scapiatawiedgman), apple fruit fly (Rhagoletis pomonella), cherry fruit fly (R. cingulata).

Hemiptera pests include, for example: megacoptapunctatissimum, eurydemarugosum, eysarcorislewisi, eysarcorisparvus, nezaraviridula, plautiastali, sycamore Halymorphamista, cletuspunctiger, leptocorisachinensis, stephantispyrioides, trigonotyluscoelestialium.

Pests of the order Homoptera include, for example, the black-tailed leafhopper (nephotettix cincticeps), the gray planthopper (laodelphax striatellus), the rice brown planthopper (nilaparvatalugens), the white-backed planthopper (sogatella furcifera), the pear psyllid (psyllapyrisuga), the citrus psyllid (diaphorinatabaci), tobacco powder Lice (bemisiatabaci), aphid (homoptera), apple cotton aphid (eriosomalanigerum).

In the order Hymenoptera, there are yellow-winged wasp (athaliarosaeruficornis), rose sawfly (argepagana), black mountain ant (formica japonica), chestnut gall wasp (dryocsmuskuriphilus) and the like.

Thysanoptera pests, such as thrips (Haplothrips Chinensis Priesner).

Pests of the class Arachnida. For example, citrus spider mite (panonychuscitri), cinnabar spider mite (Tetranychuscinnabarinus), apple spider mite (panonychusulmi), two-spotted spider mite (tetranychusurticae), hawthorn spider mite (tetranychusviennensis), small clawed mite (oligonychusununguis) citrus first leaf Eotetranychuskankitus, brevipalpusphoenicis, bryobia praetiosa, aceriatulipae, colomerus vitis, calacarus carinatus, polyphagotarsonemuslatus, long Hairy root mite (rhizoglyphus rostochiensis), etc.

From the order of Anoplura (Phthiraptera), for example Damalinias pp., Haematopinus spp., Linognathus spp., Pediculus spp., Trichodectesspp.

From the order of the Isopoda, for example, Oniscusasellus, Armadilliudium vulgare, Porcellioscaber.

From the order of the Diplopoda, for example, Blaniulus guttulatus.

From the order of the Chilopoda, for example, Geophilus carpophagus Scutigera spp.

From the order Symphyla, for example, white pine worms (Scutigerella immaculata).

From the order of the Thysanura, eg, Lepismasaccharina.

From the order of the Collembola, for example, Onychiurus armatus .

From the order of Orthoptera, for example, house crickets ( Acheta domesticus ), Gryllotal pas pp., Locustamigratoria migratioides , Melanoplus spp., Schistocerca gregaria .

From the order of the Blattaria, for example, Blatta orientalis, Periplaneta americana, Leucophaea maderae, Blattella germanica.

From the order of the Dermaptera, for example, Forficula auricularia.

From the order of the Isoptera, for example, Reticulitermesspp.

Representative organisms of the class Nematoda are nematodes selected from the group consisting of root-knot nematodes, cyst-forming nematodes, stalk nematodes and leaf nematodes. The following nematodes are preferably soybean cyst nematode (Heterodera), potato golden nematode (golboderarostochiensis), southern root-knot nematode (meloidogyneincognita), etc., which are found in the order dorylaimida, longidorus sp., and the like.

Preferably, the insecticidal composition is used for controlling scale insects, rice stem borers, rice leaf rollers, tea geometrids, beet armyworms, spodoptera litura, diamondback moths, rice planthoppers, aphids, thrips, whitefly , Greenhouse whitefly, tea leafhopper, spider mite, cabbage caterpillar, cotton bollworm.

Plants are to be understood here as meaning all plants and plant populations. Plants are plants obtainable by conventional breeding and preference methods or by biotechnological and genetic engineering methods or by combinations of these methods. The plants include transgenic plants and also plant varieties which may or may not be protected by plant breeders' rights. Plant parts are to be understood as meaning all aboveground and belowground parts and organs of said plants, such as shoots, leaves, flowers and roots, examples that may be mentioned are leaves, needles, leaves, stems, trunks, flowers, fruiting bodies, fruits and seeds, as well as roots, tubers and rhizomes. The plant parts also include harvested material and vegetative and generative propagation material, such as cuttings, tubers, rhizomes, shoots and seeds.

The useful plants that can be used for the protection of the present invention and the application of the pesticidal composition according to the present invention include: cereals such as wheat, oats, barley, triticale and rye, and corn, sorghum and chestnut, rice; sugar beet, such as sugar Beets or fodder beets; fruit such as apple fruit, stone fruit, tree nuts or soft fruit such as apples, pears, plums, peaches, bananas, almonds, walnuts, pistachios, cherries or berries such as strawberries, or blackberries; legumes Vegetables such as kidney beans, peas, or soybeans; oily plants such as canola, mustard, olive, sunflower, castor, cocoa, or peanuts; cucurbits such as watermelon, pumpkin, zucchini, cucumber, or melon; fibrous plants such as cotton, flax , hemp or jute; citrus fruits such as oranges, lemons, grapefruit or tangerines; vegetables such as spinach, lettuce, asparagus, cabbage, carrots, onions, tomatoes, red peppers, potatoes or bell peppers; lauraceae such as avocados, Cinnamon or camphor; and tobacco, nuts, coffee, eggplant, sugar cane, tea, pepper, vines, hops, plantain, gum plants, lawns, turf, forage grasses, and ornamental plants such as petunias, Pansies and impatiens.

The present invention also provides a method for preventing or controlling agricultural pests, using the pesticidal composition of the present invention on the target agricultural pests and/or their environment.

The present invention also provides a method for protecting plants from agricultural pests, comprising applying filfluben and flubenzuron separately, sequentially or simultaneously. In the case of separate applications, the sequence generally has no effect on the outcome of the control measures.

A method of preventing or controlling agricultural pests, wherein each of flubendraquine and flubendron is in the form of a formulated composition.

A method for protecting plants from agricultural pests, comprising contacting a pesticidal composition containing sulfflubenzie and flubendron with target useful plants, target agricultural pests and/or their environment, and propagation material of target useful plants.

A method for protecting plants from agricultural pests, comprising applying the pesticidal composition of the present invention before and/or after infestation of plants, plant propagation materials, and environmental pests.

The pesticidal composition of the present invention is used directly or in the form of a composition to treat agricultural pests or plants to be protected from pest attack, plant propagules such as seeds, the environment, by an insecticidally effective amount of the active compound. Application can be carried out before and after infestation of the plants, plant propagation material, environment by pests.

The treatment of plants and plant parts with the composition according to the invention is carried out directly or by acting on their environment, habitat or storage area by conventional treatment methods, such as dipping, watering, spraying, misting, broadcasting, spraying, etc. Powder, fogging, broadcasting, foaming, coating, coating, drip irrigation, etc. to the leaves of plants (foliar application). The frequency and rate of application can be adjusted to suit the level of infestation by the agricultural pest.

The pesticidal compositions according to the invention are also suitable for treating seeds. Most of the damage to crop plants caused by pests occurs as early as when the seeds are infested during storage, after they are planted in the soil, and during and immediately after emergence. This stage is especially critical because the roots and shoots of a growing plant are particularly sensitive, and even a small injury can lead to the death of the entire plant. Therefore, it is of crucial importance to protect the seed and the germinating plant by using a suitable composition.

The method for protecting seeds of the present invention does not need to additionally apply crop protection agent after planting or after plant emergence to protect seeds and germinating plants. At the same time, one aspect of the pesticidal compositions according to the invention is to provide seeds and germinating plants with optimal protection against attack by pests without causing damage to the plants themselves due to the active compounds used. Treating seeds with the pesticidal composition of the present invention not only protects the seeds themselves, but also protects the grown plants after emergence from pests. This saves the need for immediate crop treatment at sowing or shortly thereafter.

The method of seed treatment includes, for example, diluting liquid or solid medicaments or directly soaking seeds in a liquid state solution without dilution to make the medicaments permeate the seeds, mixing solid medicaments or liquid medicaments with seeds, and performing powdering. The method of coating the surface of the seed to attach the chemical agent, spraying near the seed while planting, etc. The seeds subjected to the seed treatment refer to plants at the initial stage of cultivation for plant propagation, for example, other than seeds, bulbs, tubers, potato seeds, plant buds, bulbs, or vegetative propagation for cutting cultivation. plant body. For the treatment of plant propagation material, especially seeds, the active ingredients can also be applied to the seeds by successively impregnating the tubers or grains with a liquid preparation of the respective active ingredient or by coating with a combined wet or dry preparation (coating ).

The term "plant propagation material" is understood to mean all reproductive plant parts, such as seeds, and vegetable material such as cuttings or tubers (eg potatoes). Thus, plant parts as used herein include plant propagation material. There may be mentioned, for example, seeds (in the narrow sense), roots, fruits, tubers, bulbs, rhizomes and plant parts. Also concerned are germinated plants and effective plants that are inhibited after germination from the soil or after emergence. Young plants can be protected by total or partial treatment by dipping before transplanting.

Plant parts and subsequently grown plant organs are any part of a plant produced from plant propagation material such as seeds. Plant parts, plant organs and plants may also benefit from the protection of plants from plant diseases by applying the compositions to plant propagation material. Certain plant parts and certain subsequently grown plant organs may also be considered as plant propagation material, which may itself be applied (or treated) with the composition; whereby plants produced from the treated plant parts and treated plant organs, Other plant parts and other plant organs may also benefit from protection of plants from plant pests by applying the compositions to certain plant parts and certain plant organs.

The pesticidal composition of the present invention is applied to seeds by itself or in a suitable dosage form. Preferably, the seeds are treated in a steady state such that the treatment does not cause any damage. Treatment of the seeds can generally be carried out at any time between harvesting and sowing. Care must generally be taken during seed treatment that the amount of the composition of the invention and/or the amount of other additives applied to the seed is chosen so as not to interfere with germination of the seed or to damage the resulting plant.

The pesticidal composition of the present invention is particularly advantageous for treating plant propagation material, especially the seeds of rice, rapeseed, cotton, wheat, barley, soybean, corn, peanut.

A method for protecting seeds, which comprises contacting the seeds with a synergistically effective amount of the pesticidal composition of the present invention before sowing and/or after accelerating germination.

Use of the insecticidal composition of the present invention for treating seeds.

The pesticidal composition of the present invention can be applied to the environment, habitat or storage area where the plants grow. The environment and habitat for plant growth refer to the support that can make agricultural plants take root and grow, such as: soil, water, etc. Specific raw materials can be used such as sand, pumice, vermiculite, diatomaceous earth, agar, gel , polymer substances, asbestos, sawdust, bark, etc. Soil is preferred.

The method of applying the medicament to the soil, such as diluting the liquid medicament in water or directly applying it to the root of the plant or the seedling field for raising seedlings without dilution, and spreading the granule to the root of the plant or the seedling field for raising seedlings. The method of spraying powder, water-dispersible granules, etc. in the soil before sowing and mixing them with the soil as a whole, before sowing or planting plants, dilute the powder and water-dispersible granules and spray them on the planting holes and sowing ditch. method of sowing, etc.

The soil or cultivation medium of said plant when implementing the use method of the present invention refers to the support body that can make agricultural plants take root, grow, for example: soil, water etc., concrete raw material can use for example sand, pumice, vermiculite Stone, diatomaceous earth, agar, gel, polymer, asbestos, sawdust, bark, etc.

On the other hand, the treatment according to the invention can also produce the following superadditive effects: improved plant growth, increased tolerance to high or low temperatures, increased tolerance to drought or to water or soil salinity, increased flowering quality, make harvesting easier, accelerate ripening, increase harvest yield, improve the quality and/or increase the nutritional value of the harvested product, improve the storage stability of the harvested product and/or its processing properties.

It is usual and advantageous to apply the pesticidal composition of the present invention in the following dosages:

- for foliar treatment: 0.1-10000 g/ha, preferably 10-1000 g/ha, more preferably 20-300 g/ha; for dipping or drip application, the dosage can even be lowered, especially when applying an inert substrate such as asbestos or perlite;

- for seed treatment: 2-200g/100kg seed, preferably 3-150g/100kg seed;

- For soil treatment: 0.1-10000 g/ha, preferably 1-5000 g/ha.

The above doses are only general exemplary doses, and those skilled in the art will adjust the application rate according to the actual situation and needs, especially according to the plants to be treated or the nature of the plants and the pest situation during actual application. ,

It should be noted that any embodiment of the present invention or any technical feature of an embodiment can be independently combined with any other embodiment of the present invention with each other. That is to say, one or more technical features of any embodiment of the present invention can be recombined with any other technical features. The technical features formed by the recombination of such technical features are disclosed herein as if they are specifically recorded in this document.

specific embodiment

The present invention will be further elaborated below in conjunction with embodiment.

Formulation example

Embodiment 1 emulsifiable concentrate

The above components are mixed and stirred until a uniform transparent liquid is obtained to obtain the emulsifiable concentrate preparation of the present invention.

Embodiment 2 wettable powder

The wettable powder of the present invention is obtained by mixing the active ingredients, various additives and fillers according to the ratio of the formula, and pulverizing them with an ultrafine pulverizer.

Embodiment 3 water emulsion

Add the original drug, solvent and emulsifier together to dissolve into a uniform oil phase; mix the water-soluble components with water to obtain a water phase; mix the oil phase with the water phase under high-speed stirring to obtain the present invention water emulsion.

Embodiment 4 water dispersible granules

The active ingredient, dispersant, wetting agent, disintegrating agent and filler are mixed evenly according to the ratio of the formula, crushed into a wettable powder by airflow, and then a certain amount of water is added to mix and extrude to granulate. The water-dispersible granules of the present invention are obtained after drying and sieving.

Embodiment 5 water dispersible granules

The active ingredient, dispersant, wetting agent, disintegrating agent and filler are mixed evenly according to the ratio of the formula, crushed into a wettable powder by airflow, and then a certain amount of water is added to mix and extrude to granulate. The water-dispersible granules of the present invention are obtained after drying and sieving.

Embodiment 6 wettable powder

The wettable powder of the present invention is obtained by mixing the active ingredients, various additives and fillers according to the ratio of the formula, and pulverizing them with an ultrafine pulverizer.

Embodiment 7 suspoemulsion

Dissolve fluoride praquin in SOLVESSO ^TM 100, add ethoxylated castor oil to obtain emulsifiable concentrate; mix fluoride, disodium fatty alcohol polyoxyethylene ether sulfosuccinate monoester, modified calcium lignosulfonate , Xanthan gum, bentonite, glycerin, water and other above-mentioned components are mixed uniformly in proportion, and are sand-milled to prepare a suspending agent containing flufenuron. Adding the oil phase containing flufenzuron into the suspending agent containing flufenzuron to obtain a suspoemulsion.

Embodiment 8 water emulsion

Oil phase:

water box:

Dissolving fiflubenzaquin and fiflubenzuron in methyl oleate, adding polystyrene to obtain an oil phase; mixing the components uniformly according to the formula to obtain a water phase; adding the oil phase to the water phase under stirring to obtain a water emulsion.

Embodiment 9 wettable powder

Fluproquine 70% Flubenzuron 20% Alkylnaphthalene formaldehyde condensate sulfonate 7% sodium lauryl sulfate 2% light calcium carbonate Top up to 100%

The above combinations are mixed in proportion, ground and pulverized to prepare wettable powder.

Embodiment 10 coated granules

In a mixer, the finely divided active ingredient is spread homogeneously onto a carrier moistened with polyethylene glycol. Dust-free coated granules can be obtained in this way.

Embodiment 11 wettable powder

Fluproquine 5% Flubenzuron 25% Sodium lignosulfonate 10% Sodium dodecyl sulfonate 3% Silica 5% Kaolin Top up to 100%

The above components are mixed in proportion, ground and pulverized to prepare wettable powder.

Example 12 extruded granules

The active ingredient is mixed with the auxiliaries and ground, and the mixture is moistened with water. The mixture is extruded and dried in a stream of air.

Embodiment 13 suspoemulsion

Dissolve flubendron in SOLVESSO ^TM 200, add ethoxylated castor oil to obtain emulsifiable concentrate; mix flubendraquine, disodium fatty alcohol polyoxyethylene ether sulfosuccinate monoester, modified calcium lignosulfonate , xanthan gum, bentonite, glycerol, water and other above-mentioned components are uniformly mixed in proportion, and sand-milled to prepare a suspension containing sulfamidine. The oil phase containing flubendron is added to the suspending agent containing flubendraquine to obtain a suspoemulsion.

Embodiment 14 suspoemulsion

Fluproquine 50% Flubenzuron 2% SOLVESSO ^™ 200 10% Ethoxylated castor oil 4% Modified Calcium Lignosulfonate 5% xanthan gum 0.5% Bentonite 1% Glycerol 5% Defoamer 0.6% water Top up to 100%

Dissolve flubendron in SOLVESSO ^TM 200, add ethoxylated castor oil to obtain flubendron-containing emulsifiable concentrate; mix flubendraquine, disodium fatty alcohol polyoxyethylene ether sulfosuccinate monoester, modified wood Calcium sulfonate, xanthan gum, bentonite, glycerin, water and other above-mentioned components are uniformly mixed in proportion, and sand-milled to prepare the sulfamidine suspension.

The oil phase containing flubendron is added to the suspending agent containing flubendraquine to obtain suspoemulsion.

Embodiment 15 emulsifiable concentrate

Fluproquine 5% Flubenzuron 15% N-Methylpyrrolidone 20% Ethoxylated castor oil 4% Calcium dodecylbenzenesulfonate 10% SOLVESSO ^™ 200 Top up to 100%

The above components are mixed and stirred until a uniform transparent liquid is obtained to obtain the emulsifiable concentrate of the present invention.

Example 16 Microcapsule Suspension-Suspension Concentrate

ATLOX ^™ 4913 1% citric acid 0.05% catalyst 0.1% water 10% Flubenzuron 5% PAPI 1.35% methyl oleate 10% ATLOX ^™ 4913 16% Defoamer 0.16% urea 8.4% Fluproquine 25% water Top up to 100%

The oil phase formed by polymethylene polyphenyl polyisocyanate (PAPI), fiflubenzuron and methyl oleate was added to the aqueous solution containing ATLOX ^TM 4913 to form an emulsion. Then heat and keep warm at 50 ^o C and add the catalyst to react for 2 hours. After cooling, microcapsules containing flufenuron are obtained.

ATLOX ^TM 4913, dispersant LFH, defoamer, urea, firfluraquine and water are mixed uniformly in proportion and sand milled to prepare a suspension.

The obtained microcapsules containing flubendron are added into the water suspension containing flufenizine, and stirred evenly to obtain the microcapsule suspension-suspension of the present invention.

Embodiment 17 suspension seed coating agent

Fluproquine 50% Flubenzuron 5% Cyclohexanone 20% Butanol PO/EO Copolymer 5% Tristyrene phenol (10-20EO) 5% xanthan gum 0.5% Glycerol 5% Polyvinylpyrrolidone (PVP-K30) 1% Defoamer 0.6% water Top up to 100%

Dissolve flubendron in cyclohexanone, add butanol PO/EO copolymer to obtain emulsifiable concentrate containing flubendron; mix flubendraquine, tristyrene phenol (10-20EO), xanthan gum, glycerine Alcohol, polyvinylpyrrolidone, water and other above-mentioned components are uniformly mixed in proportion, and sand-milled to prepare a suspending agent.

The oil phase containing flubendron is added to the suspending agent containing flubendraquine to obtain the suspension seed coating agent of the present invention.

Example 18 Aerosol

Fluproquine 5% Flubenzuron 5% Propylene Glycol 5% Phosphates 3.5% Ethoxylated castor oil 2.0% SOLVESSO ^™ 100 Top up to 100%

First, mix the antifreeze propylene glycol and diluent SOLVESSO ^TM 100, and add fiflubenzaquin and fiflubenzuron while stirring; add the surfactant, and crush it through a colloid mill of a crushing equipment under stirring, and pass through the colloid mill. The suspension is then passed through a micronizer. Cycle back and forth until the particle size of the solid particles is less than or equal to 2um.

Embodiment 19 wettable powder

Fluproquine 50% Flubenzuron 5% Sodium dodecyl sulfate 1% Sodium lignosulfonate 1% Silica 1% Kaolin Top up to 100%

The wettable powder of the present invention is obtained by mixing the active ingredients, various additives and fillers according to the ratio of the formula, and pulverizing them with an ultrafine pulverizer.

Embodiment 20 oil suspension

Fluramipriquine 10%

Flubenzuron 20%

Sodium methyl naphthalene sulfonate formaldehyde condensate 5%

Bentonite 5%

Glycerol 5%

Corn oil supplemented to 100%

The components of the active component, the dispersant and the wetting agent are uniformly mixed according to the ratio of the formula, and after grinding and/or high-speed shearing, corn oil is added to obtain an oil suspension.

Embodiment 21 wettable powder

Fluproquine 10% Flubenzuron 0.1% Sodium dodecyl sulfate 1% Sodium lignosulfonate 1% Silica 1% light calcium carbonate Top up to 100%

The wettable powder of the present invention is obtained by mixing the active ingredients, various additives and fillers according to the ratio of the formula, and pulverizing them with an ultrafine pulverizer.

Embodiment 22 emulsifiable concentrate

Fluproquine 0.1% Flubenzuron 10% N-Methylpyrrolidone 20% Ethoxylated castor oil 4% Calcium dodecylbenzenesulfonate 10 SOLVESSO ^™ 200 Top up to 100%

The above components are mixed and stirred until a uniform transparent liquid is obtained to obtain the emulsifiable concentrate of the present invention.

Embodiment 23 concentrated suspending agent

Concentrated suspensions are obtained by mixing with auxiliaries the finely divided active ingredient.

Embodiment 24 seed treatment dry powder

The active ingredient is thoroughly mixed with the adjuvant, and the mixture is thoroughly ground in a suitable mill to obtain a powder that can be directly used for seed treatment.

Example 25 Active ingredient composition

Mix fluoripraquine and flufenuron evenly in proportion.

Proportioning in above embodiment is weight percentage proportioning.

biological test case

Combining the active ingredients of different pesticides to make pesticides is an effective and fast way to develop and develop new pesticides and prevent and control resistant pests in agriculture. When pesticides of different varieties are mixed, they usually show three types of effects: additive effect, synergistic effect and antagonistic effect. However, it is impossible to predict the specific role, and it can only be known through a large number of experiments. The formula with good compounding and synergistic effects can significantly improve the actual control effect and reduce the use of pesticides, thereby greatly delaying the development of pest resistance, and is an important means of comprehensive pest control.

The inventor has carried out a large number of tests and effect analysis on the different proportions of flubendraquine and flubenzuron through a large number of screening tests, and found that within a certain proportion range, the obtained insecticidal composition has a gain effect, It is not just the simple addition of two medicines, but will be specifically described in the following embodiments.

In the embodiment of the present invention, the indoor toxicity measurement method is adopted. Through the indoor toxicity measurement, the co-toxicity coefficient (CTC) after the two drugs are compounded in a certain proportion is clarified. CTC<80 is an antagonistic effect, and 80≤CTC≤120 It is an additive effect, and CTC>120 is a synergistic effect.

Test method: During the test, the insecticidal composition reagents prepared in the above examples were diluted into five series of concentrations, and placed in beakers for subsequent use. Then adopt the method of soaking the leaves first and then inoculating them. Leaves of the same size that have not been exposed to any pesticides are soaked in the prepared medicinal solution for 5 seconds, taken out, dried naturally, put into the insect breeding box, and then connected with the larvae for testing. , reared under the condition of 25°C, each treatment was repeated 3 times, and the number of test insects used in each repetition was 20, and a blank control was set at the same time, the number of dead insects was checked at 72 hours, the mortality rate and the corrected mortality rate were calculated, and the regression equation of toxicity was obtained. And calculate the _LC50 value. If the control mortality rate was greater than 10%, the trial was considered invalid. Calculated as follows:

Mortality rate (%) = (number of live insects before treatment - number of live insects after treatment) / number of live insects before treatment * 100

Corrected mortality rate (%) = (death rate in treatment group - mortality rate in control group) / (100 - mortality rate in control group) * 100

Convert the corrected death rate of the tested insects into a probability value (y), and convert the treatment concentration (μg/ml) into a logarithmic value (x), and use the least square method to obtain the regression equation of toxicity, and thus calculate the toxicity of each agent. value. The co-toxicity coefficient CTC was calculated according to Sun Yunpei's formula. The calculation formula is as follows (taking filamipraquin as the standard agent, its toxicity index is 100):

Actual toxicity index (ATI) = (standard drug LC ₅₀ / test drug LC ₅₀ ) × 100

Theoretical toxicity index (TTI) = A drug ATI × the percentage of A in the mixture + B drug ATI × the percentage of B in the mixture

Co-toxicity coefficient (CTC) = (mixture ATI/mixture TTI) × 100

Experiment 1: Indoor Toxicity Determination of Cotton Aphids

Table 1

As can be seen from Table 1, when the ratio of fluorfenpyraquine and fiflubenzuron is in the range of 1:100-100:1 for the control of cotton aphids, the co-toxicity coefficients are all greater than 120, indicating that both of them are mixed in this range. Appears as a gain effect.

Experiment 2: Indoor toxicity test results for Bemisia tabaci

Table 2

It can be seen from Table 2 that, when the ratio of 1:100-100:1 is used for the prevention and treatment of Bemisia tabaci, the co-toxicity coefficients of the two are greater than 120, indicating that the two are mixed in this range. Both show a gain effect.

Experiment 3: Results of indoor toxicity test on citrus scale insects

table 3

It can be seen from Table 3 that when the ratio of citrus scale insects is controlled by flubendraquine and flubenzuron in the range of 1:100-100:1, the co-toxicity coefficients are all greater than 120, indicating that the two are mixed in this range. Both show a gain effect.

Experiment 4: Indoor toxicity test results for cotton bollworm

Table 4

As can be seen from Table 4, when fluoriprazine and fluoridenzuron prevent and control cotton bollworm, in the scope of proportioning 1:100-100:1, the co-toxicity coefficients are all greater than 120, indicating that both are mixed in this range. Appears as a gain effect.

Experiment 5: Indoor toxicity test results for citrus spider mite

table 5

It can be seen from Table 5 that when the ratio of 1:100-100:1 is used to prevent and control citrus red spider mites, the co-toxicity coefficients of the two are greater than 120, indicating that the two are mixed within this range. Both show a gain effect.

Experiment 6: Indoor toxicity test results for tea leafhoppers

Table 6

As can be seen from Table 6, when the ratio of 1:100-100:1 is used for the prevention and treatment of tea leafhoppers, the co-toxicity coefficients of fluoripraquine and fluoridenuron are all greater than 120, indicating that the two are mixed in this range. The distribution is expressed as a gain effect.

Experiment 7: Indoor toxicity test results for Plutella xylostella

Table 7

As can be seen from Table 7, when the ratio of 1:100-100:1 is used to prevent and control diamondback moth, the co-toxicity coefficients of fluoriprazine and fluoridenuron are all greater than 120, which shows that both of them are well mixed in this range. Appears as a gain effect.

In addition, according to the above method of virulence determination, the results of indoor virulence determination on apple claw mite, thrips, rice leaf roller, rice stem borer, greenhouse whitefly, tea geometrid, and beet armyworm also showed that sulfluramid Quinoquine and flubenzuron control apple claw mite, thrips, rice leaf roller, rice borer, greenhouse whitefly, tea looper, and beet armyworm. When the ratio is 1:100-100:1, co-toxicity The coefficients are all greater than 120, indicating that the mixing of the two in this range shows a gain effect.

Claims (17)

1. An insecticidal composition, characterized in that it comprises sulfamidine (formula I) Formula (I) and flufenuron (formula II), Formula (II) The weight ratio of the flubendraquine to flubenzuron is 1:100 to 100:1. 2. The insecticidal composition according to claim 1, characterized in that: the weight ratio of said fiflubenzaquin to flubenzuron is 1:50 to 50:1. 3. The insecticidal composition according to claim 1, characterized in that: the weight ratio of said fiflubenzaquin to flubendron is 1:25 to 25:1. 4. The insecticidal composition according to claim 1, characterized in that: the weight ratio of said fiflubenzaquin to flubenzuron is 1:10 to 10:1. 5 . The insecticidal composition according to claim 1 , characterized in that: said fiflubenzaquin and fiflubenzuron together account for 1%-90% of the composition by weight. 6 . The insecticidal composition according to claim 1 , characterized in that: said fiflubenzaquin and flubenzuron together account for 10%-80% of the composition by weight. 7 . The insecticidal composition according to claim 1 , characterized in that: said fiflubenzaquin and fiflubenzuron together account for 20%-60% of the composition by weight. 8. The insecticidal composition according to claim 1, further comprising a surfactant and/or an extender. 9. The insecticidal composition according to claim 1, characterized in that: said dosage form is emulsifiable concentrate, suspension concentrate, seed coating, water dispersible granule, wettable powder, suspoemulsion, extrusion granule, coating Granules, aerosols, water emulsions, microcapsule suspensions, ultra-low volume liquids. 10. Use of the pesticidal composition according to claim 1 for preventing or controlling agricultural pests. 11. A method for preventing or controlling agricultural pests, characterized in that: the pesticidal composition according to claim 1 is used for target agricultural pests and/or their environment. 12. A method for preventing or controlling agricultural pests according to claim 11, characterized in that: said agricultural pests are selected from the group consisting of scale insects, rice stem borers, rice leaf rollers, tea geometrids, beet armyworms, and Spodoptera litura Moth, diamondback moth, rice planthopper, aphids, thrips, whitefly, greenhouse whitefly, tea leafhopper, spider mite. 13. A method for preventing or controlling agricultural pests according to claim 11, characterized in that it comprises applying filfluben and flubenzuron separately, sequentially or simultaneously. 14. A method for preventing or controlling agricultural pests according to claim 11, wherein each of fiflubenzaquin and fiflubenzuron is in the form of a formulated composition. 15. A method for protecting plants from agricultural pests, characterized in that: the pesticidal composition according to claim 1 is contacted with target useful plants, target agricultural pests and/or their environment, and the propagation material of target useful plants . 16. A method for protecting plant seeds, characterized by comprising contacting the seeds with an effective amount of the insecticidal composition according to claim 1 before sowing and/or after accelerating germination. 17. A method for protecting plants from agricultural pests, comprising applying the pesticidal composition of claim 1 before and/or after plants, plant propagation materials, and environments are infested by agricultural pests.