CN1055023C - Wound nursing agent - Google Patents
Wound nursing agent Download PDFInfo
- Publication number
- CN1055023C CN1055023C CN93100548A CN93100548A CN1055023C CN 1055023 C CN1055023 C CN 1055023C CN 93100548 A CN93100548 A CN 93100548A CN 93100548 A CN93100548 A CN 93100548A CN 1055023 C CN1055023 C CN 1055023C
- Authority
- CN
- China
- Prior art keywords
- nursing agent
- wound
- epidermal growth
- growth factor
- wounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000000474 nursing effect Effects 0.000 title claims abstract description 20
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 19
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 18
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims abstract description 15
- 102000009024 Epidermal Growth Factor Human genes 0.000 claims abstract description 8
- 101800003838 Epidermal growth factor Proteins 0.000 claims abstract description 8
- 229940116977 epidermal growth factor Drugs 0.000 claims abstract description 8
- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 claims abstract description 8
- HHVIBTZHLRERCL-UHFFFAOYSA-N sulfonyldimethane Chemical compound CS(C)(=O)=O HHVIBTZHLRERCL-UHFFFAOYSA-N 0.000 claims 2
- 208000027418 Wounds and injury Diseases 0.000 abstract description 16
- 206010052428 Wound Diseases 0.000 abstract description 15
- 230000004220 muscle function Effects 0.000 abstract description 3
- 230000008467 tissue growth Effects 0.000 abstract description 3
- 238000005516 engineering process Methods 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 208000032544 Cicatrix Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000835 fiber Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 231100000241 scar Toxicity 0.000 abstract 1
- 230000037387 scars Effects 0.000 abstract 1
- 229960001760 dimethyl sulfoxide Drugs 0.000 description 6
- 102000018386 EGF Family of Proteins Human genes 0.000 description 4
- 108010066486 EGF Family of Proteins Proteins 0.000 description 4
- 210000000589 cicatrix Anatomy 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 230000006378 damage Effects 0.000 description 3
- 208000002847 Surgical Wound Diseases 0.000 description 2
- 239000003708 ampul Substances 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 150000003462 sulfoxides Chemical class 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention relates to a wound nursing agent, the weight percentage of dimethyl sulfoxide to medicinal ethanol in the nursing agent is 10 to 30:70 to 90, and in addition, a liquid epidermal growth factor of 1 to 50 mu G/ml is added. Utilizing an epidermal growth factor can restore most muscle functions, inhibit fiber tissue growth and avoid healed wound scars. The wound nursing agent has the advantages of good effect and simple manufacturing technology, and is suitable for small wounds or common wounds and operative wounds.
Description
The present invention relates to a kind of nursing agent, particularly a kind of Wound nursing agent.
Wound healing generally all stays cicatrix, and particularly after the operation, cicatrix is more obvious, makes perfect human body stay blemishes, and because operation can make the muscular tissue function damage.
The objective of the invention is to avoid above-mentioned the deficiencies in the prior art part and a kind of most recovery of muscle function that makes is provided, and suppress fibrous tissue growth, make recovery from illness back wound not stay the Wound nursing agent of cicatrix.
Purpose of the present invention can reach by following measure: the invention is characterized in that the percentage by weight of dimethyl sulfoxide and medical ethanol is 10～30: 70～90 in the nursing agent, add l～50 μ G/ml solution epidermal growth factors in addition again.
Purpose of the present invention can also reach by following measure: the percentage ratio of the weight of two basic first sulfoxides and medical ethanol is got 30: 70 for best in the nursing agent, and the epidermal growth factor of adding is got 50 μ G/ml solution for best.
During making, epidermal growth factor is dissolved in the dimethyl sulfoxide, again dimethyl sulphoxide solution is added in the ethanol, be loaded on ampoule, place zubzero temperature to preserve.
The present invention has following advantage compared to existing technology: utilize epidermal growth factor can make the most recovery of muscle function, and the inhibition fibrous tissue growth makes recovery from illness back wound not stay cicatrix, and is respond well, manufacturing process is simple, makes to close in general damage and surgical wound and uses.
The present invention will now be further detailed embodiment:
Embodiment one:
Get in the dimethyl sulfoxide that 5 μ G/ml solution epidermal growth factors are dissolved in 10% the ratio of accounting for, above-mentioned solution is added account in the medical ethanol of 90% ratio again, promptly can be made into Wound nursing agent of the present invention.At last it being loaded on ampoule places zubzero temperature to preserve (annotate: at finished product, the shared ratio of epidermal growth factor is minimum, can ignore not accounting example).The nursing agent of this kind proportioning is suitable for minor cut or wound to be used.
Embodiment two:
Getting 2 μ G/ml solution epidermal growth factors is dissolved in the dimethyl sulfoxide that accounts for 20% ratio, again above-mentioned solution is added and account in the medical ethanol of 80% ratio, promptly can be made into Wound nursing agent of the present invention, the nursing agent of this kind proportioning is suitable for general injury to be used.
Embodiment three:
Get 50 μ G/ml solution epidermal growth factors and be dissolved in the dimethyl sulfoxide that accounts for 30% ratio, more above-mentioned solution adding is accounted in the medical ethanol of 70% ratio, promptly can be made into Wound nursing agent of the present invention.The nursing agent of this kind proportioning is applicable to the surgical wound use.
Claims (2)
1, a kind of Wound nursing agent is characterized in that the percentage by weight of dimethyl sulfoxide and medical ethanol is 10～30: 70～90 in the nursing agent, adds 1～5 μ G/ml solution epidermal growth factor in addition again.
2, nursing agent according to claim 1 is characterized in that the percentage by weight of dimethyl sulfone and medical ethanol is got 30: 70 for best in the nursing agent, and the epidermal growth factor of adding is got 50 μ G/ml solution for best.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93100548A CN1055023C (en) | 1993-01-03 | 1993-01-03 | Wound nursing agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93100548A CN1055023C (en) | 1993-01-03 | 1993-01-03 | Wound nursing agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1083390A CN1083390A (en) | 1994-03-09 |
| CN1055023C true CN1055023C (en) | 2000-08-02 |
Family
ID=4983092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93100548A Expired - Fee Related CN1055023C (en) | 1993-01-03 | 1993-01-03 | Wound nursing agent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1055023C (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN85103719A (en) * | 1985-05-13 | 1986-05-10 | 晏明 | Produce the method for quick-acting antiinflammatory antianaphylaxis components from Corium elephatis |
| CN87101250A (en) * | 1986-11-14 | 1988-06-08 | 分子生物学研究有限公司 | wound treatment |
| CN1047449A (en) * | 1990-07-02 | 1990-12-05 | 南京化学厂 | The health nourishing tooth-paste that contains fibroin |
-
1993
- 1993-01-03 CN CN93100548A patent/CN1055023C/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN85103719A (en) * | 1985-05-13 | 1986-05-10 | 晏明 | Produce the method for quick-acting antiinflammatory antianaphylaxis components from Corium elephatis |
| CN87101250A (en) * | 1986-11-14 | 1988-06-08 | 分子生物学研究有限公司 | wound treatment |
| CN1047449A (en) * | 1990-07-02 | 1990-12-05 | 南京化学厂 | The health nourishing tooth-paste that contains fibroin |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1083390A (en) | 1994-03-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Singer et al. | Prospective, randomized, controlled trial of tissue adhesive (2‐octylcyanoacrylate) vs standard wound closure techniques for laceration repair | |
| Milburn et al. | Treatment of scleroderma skin ulcers with a hydrocolloid membrane | |
| DE59600683D1 (en) | Use of trospium chloride in the manufacture of a medicament for the treatment of bladder diseases | |
| CA2064039A1 (en) | Treatment to reduce edema for brain and musculature injuries | |
| CN1055023C (en) | Wound nursing agent | |
| Zöch et al. | Reduction of the mortality rate in aged burn patients | |
| US5789445A (en) | Method for topical treatment of scar tissue and related tissue reaction to trauma | |
| CN112354005B (en) | Dressing for promoting healing of burn and scald wound surfaces and preparation method thereof | |
| CN112933214A (en) | Composition for promoting wound healing | |
| Ikeda et al. | Successful surgical management and long‐term follow‐up of epidermolysis bullosa | |
| US5547672A (en) | Accelerated wound healing | |
| Bayley | Wound healing in the patient with burns | |
| AU3423493A (en) | Methods and compositions for reducing blood loss | |
| ES2182840T3 (en) | FACTOR XIII FOR THE TREATMENT OF SKIN WOUNDS. | |
| Dolezal et al. | Early treatment of rhinophyma—a neglected entity? | |
| Eastwood et al. | Bier's block—an improved technique | |
| CN115645476A (en) | Application method of medicine powder for removing toxin and promoting tissue regeneration after gun and knife trauma, medicine powder for removing toxin and promoting tissue regeneration after gun and knife trauma and preparation method | |
| Cooper et al. | Topical negative pressure in the treatment of pressure ulcers | |
| RU2003344C1 (en) | Method for burn disease treatment | |
| Loudon | Leg ulcers in the eighteenth and early nineteenth centuries. II. Treatment | |
| CN2321402Y (en) | Pressurized screw bolt by outer skin fixing | |
| RU1782597C (en) | Method for prevention of necrosis of the skin pedicle graft | |
| Azad et al. | Hypertrophie scars and keloids: an overview of the aetiology and management | |
| Grasso et al. | Keratinocyte growth factor 2 promotes wound healing | |
| Balakrishnan et al. | Burns of the lymphoedematous extremity |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |